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Search of human proteins with 239757964
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
(290 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 590 e-169
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 268 3e-72
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 233 1e-61
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 197 9e-51
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 185 5e-47
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 184 8e-47
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 182 4e-46
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 149 3e-36
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 149 3e-36
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 147 1e-35
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 141 8e-34
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 129 3e-30
gi|148746195 trichohyalin [Homo sapiens] 122 3e-28
gi|52426743 cisplatin resistance-associated overexpressed protei... 117 1e-26
gi|19923485 cisplatin resistance-associated overexpressed protei... 117 1e-26
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 115 6e-26
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 114 8e-26
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 110 1e-24
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 107 9e-24
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 104 8e-23
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 104 8e-23
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 103 1e-22
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 103 1e-22
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 103 2e-22
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 103 2e-22
gi|20070262 TNF receptor-associated factor 3 interacting protein... 102 5e-22
gi|213385278 TNF receptor-associated factor 3 interacting protei... 100 2e-21
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 100 2e-21
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 99 4e-21
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 99 4e-21
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 590 bits (1520), Expect = e-169
Identities = 290/290 (100%), Positives = 290/290 (100%)
Query: 1 MGCEWGGQSLGNSSPVKTSPLLVPSLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESP 60
MGCEWGGQSLGNSSPVKTSPLLVPSLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESP
Sbjct: 1 MGCEWGGQSLGNSSPVKTSPLLVPSLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESP 60
Query: 61 RSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTE 120
RSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTE
Sbjct: 61 RSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTE 120
Query: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ
Sbjct: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD 240
KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD
Sbjct: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD 240
Query: 241 RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP
Sbjct: 241 RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 268 bits (686), Expect = 3e-72
Identities = 157/344 (45%), Positives = 213/344 (61%), Gaps = 87/344 (25%)
Query: 30 PHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQR----ERDRVR 85
P LGTLWVEVTIPLDFSR R GSQESPR GLGQAHKDADGDDR+R ER+R R
Sbjct: 7 PATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRR 66
Query: 86 EKTEKERDRDRKRDRER---------RRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
EK + ER+ DRKR+R R R +E++ +R ++RE+QT+ ERDR+REK++ R++E
Sbjct: 67 EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126
Query: 137 RDRG----------------RERERDRDREKERERQTEKDRDGQRETETERERDRE---- 176
R+R RERER RD EKERERQT+++R Q E ++ER+RE
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ 186
Query: 177 ----REKQKERET-----------ERDRDRQRDTEKERERQTDRERDRQRKTQTERQ--- 218
RE+Q+E+E ER+R+R+ +TE ER+RQTDRERDRQRKT+ ER+
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 219 -------------------RETDR-------EGERETDRRR----------ERQRDRDRG 242
R+ DR E ER+TDR+R ER+R+R R
Sbjct: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+ER+RER+RK ER++ER++ER+++R+ ++ EK RE K+++ E
Sbjct: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Score = 207 bits (527), Expect = 9e-54
Identities = 104/235 (44%), Positives = 168/235 (71%), Gaps = 16/235 (6%)
Query: 67 QAHKDADGDDRQRERDRVREK-------TEKERDRDRKRDRERR-RKEKETNRNRDREKQ 118
Q K+ +DR ER R RE+ TE++R DR+RDR+R+ +E+E R+R +
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 119 TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
E ERD+ERE+++ R+R+RDR R++ER+R +++R+R+TE+DR+ +R+ E +RER+RERE
Sbjct: 254 RETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 179 K----QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
+ ++ERE ER+R+RQR+TE++RE++ +R+R RQ + ER R+T REG R+ +R RE
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 235 RQRDRDRGKER---DRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
R+R+RDR R +RERDR +R+KER+++ +K+R +++ EK+RE +K + E
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
Score = 197 bits (500), Expect = 1e-50
Identities = 97/211 (45%), Positives = 160/211 (75%), Gaps = 14/211 (6%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR--EKQTEIERDREREKQKGR 133
+R+ ERD+ RE+ ERDRDR RDR ++ +E++T+R R R E+ E ER RER++++ R
Sbjct: 253 ERETERDKERER---ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRE------TETERERDRE--REKQKERET 185
ERER+R RERER+R+RE+ER+R+TE+DR+ +RE TE +RER+R+ RE +++ E
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
Query: 186 ERDRDRQRDTEKERER-QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
ER+R+R+RD + RER + +R+RDR R+ + ERQ E DR+G+RET+++RER++DR+ +
Sbjct: 370 ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG 429
Query: 245 RDRERDRKEERKKERKKERKKERKEKKKEEK 275
R+R R+R++++ +ER +ER+ +R+ ++ ++
Sbjct: 430 RERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 191 bits (486), Expect = 5e-49
Identities = 92/223 (41%), Positives = 155/223 (69%), Gaps = 16/223 (7%)
Query: 76 DRQRERDRVREKTEKER-DRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+R R+++R REK +ER +R+R+R++E + +++ + R R+RE++ E E + ER++Q RE
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR-----EREKQ--------- 180
R+R R ERER++ E+ER + E +RD +RE E +R+RDR ERE+Q
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 181 -KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
++RETER R+RQR+ E+ERER RER+R+R+ + ERQRET+R+ E+E +R+R+RQ +
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
Query: 240 DRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
DR + R R+ + + ++ER++ER+++R+ ++ E+R D+ R
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
Score = 188 bits (478), Expect = 4e-48
Identities = 98/223 (43%), Positives = 160/223 (71%), Gaps = 21/223 (9%)
Query: 76 DRQRERDRVREK-------TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRERE 128
DRQR+ +R REK +E+E +RD++R+RER R R ++RE+QT+ R R+R
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD--RKRQRR 290
Query: 129 KQKGRERERDRGRERERDRDRE--KERERQTEKDRDGQRETETERERDREREKQKERETE 186
++ RE ER R R+RER+R+RE ++RER+ E++R+ +R+ ETER+R++ERE++++R+TE
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Query: 187 RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDRE-GERETDRRRERQRDRDRGKER 245
DR+R R T +E RQ +RER+R+R ER R++ RE ERE DR R+RQ++R+R E+
Sbjct: 351 MDRERNRQTGREGRRQAERERERER----ERDRQSAREREERERDRDRDRQKERERQTEK 406
Query: 246 DRERDRKEERKKERKKERKKER-----KEKKKEEKRREDKKRK 283
DR+ R+ E+++ER+K+R+ ER +E++K++ R D++R+
Sbjct: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Score = 169 bits (428), Expect = 3e-42
Identities = 100/239 (41%), Positives = 146/239 (61%), Gaps = 24/239 (10%)
Query: 76 DRQRERDRVREKTEK-ERDRDRKRDRERRR---KEKETNRNRDREKQTEIERDRER---- 127
+RQRER+R RE+ K ER+R+R+R+RER+R +++E R R R++QTE++R+R R
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
Query: 128 ------EKQKGRERERDRG-------RERERDRDREKERERQTEKDRDGQRETETERERD 174
E+++ RERERDR RER+RDRDR+KERERQTEKDRDGQRETE +RER+
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 175 REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT---ERQRETDREGERETDR 231
++RE ++ RE R+R++Q+ E++RERQTDR+ RQRK T T R G ++D
Sbjct: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
Query: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
R + R + D + K + +++ E R +K+ + GEG P
Sbjct: 482 NRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP 540
Score = 94.0 bits (232), Expect = 1e-19
Identities = 48/119 (40%), Positives = 74/119 (62%), Gaps = 1/119 (0%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110
R R + R+ G+ + +R+RER+R R+ + +R+R RDR+ R+KE+E
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD-RQKERERQ 403
Query: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
+DR+ Q E E+ REREK + ER R+RGRERE+ + RE++RERQT++ QR+ T
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 73.6 bits (179), Expect = 2e-13
Identities = 37/109 (33%), Positives = 70/109 (64%), Gaps = 3/109 (2%)
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER--QRD 238
+ R ++ R+R + + +R+R R+ + ER+RE R+ ERETDR+RER ++D
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERRREKD 86
Query: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
R R ++R RER R E+++ER+ +R+++R+ +K+ +++E ++ EG
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 233 bits (595), Expect = 1e-61
Identities = 116/216 (53%), Positives = 166/216 (76%), Gaps = 16/216 (7%)
Query: 76 DRQRERDRVREK-TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+RQRER R ++ E ER+RDR+R+RE + + + +R RDR + ERDR+ +++K RE
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHR----ERDRQTDREKERE 57
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
R+++R R+R+R+R+ E+E ERQ E+ R +R+ +T+RERD++R+++++RET+R+R+R R
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
+ER++QT+RERDR+R ERQR+ +RE +R+ +R+RE R+R R ER EE
Sbjct: 118 GGRERDKQTERERDRER----ERQRQRERERQRQRERKRETDRERQRWAER-------EE 166
Query: 255 RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP
Sbjct: 167 RKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 202
Score = 76.6 bits (187), Expect = 2e-14
Identities = 47/114 (41%), Positives = 76/114 (66%), Gaps = 16/114 (14%)
Query: 70 KDADGD-DRQRERDRVREKTEKE-RDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER 127
+D D D +R+RE DR RE+ K R+RD++ +RE R+R+RE+Q R RER
Sbjct: 96 RDKDRDRERKRETDRNRERNRKGGRERDKQTERE---------RDRERERQ----RQRER 142
Query: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
E+Q+ RER+R+ RER+R +RE ER+++ +K+R +R+ + + E+ RE +K+K
Sbjct: 143 ERQRQRERKRETDRERQRWAERE-ERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/91 (34%), Positives = 56/91 (61%), Gaps = 13/91 (14%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGD---DRQRERDRVREKTEKERDRDRKR----DRERR 103
R R G +E + Q ++ D + RQRER+R R++ E++R+ DR+R +RE R
Sbjct: 114 RNRKGGRERDK-----QTERERDRERERQRQRERERQRQR-ERKRETDRERQRWAEREER 167
Query: 104 RKEKETNRNRDREKQTEIERDREREKQKGRE 134
+KE++ R ++R+++ + E+ RE +K+K E
Sbjct: 168 KKERKKERKKERKEKKKEEKRREDKKRKWGE 198
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 197 bits (501), Expect = 9e-51
Identities = 111/213 (52%), Positives = 146/213 (68%), Gaps = 15/213 (7%)
Query: 69 HKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRERE 128
H + + DRQRER R +T++ERDR ++ E R E++ R RDRE+ E +RDRERE
Sbjct: 11 HTETETMDRQRER---RRETDRERDRAKESKTEDRHSERD--RQRDRERNRERDRDRERE 65
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
KQ RE ER R RER+RDR RE ERER D +RET+ E DRER+KQKERE ER
Sbjct: 66 KQTDREGERQRERERDRDRQRETERER------DKERETDRHTETDRERQKQKEREMERV 119
Query: 189 RDRQRDTEKE--RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
RDR+R+ +KE RERQTDRE DR+R+ Q ER+RET RE + E DR RER+R+R R +ER
Sbjct: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-DRHRERERERKRERERK 178
Query: 247 RE-RDRKEERKKERKKERKKERKEKKKEEKRRE 278
RE ++R+ ER+++R+ +RK ++ E RE
Sbjct: 179 RETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 172 bits (436), Expect = 3e-43
Identities = 89/201 (44%), Positives = 143/201 (71%), Gaps = 13/201 (6%)
Query: 95 DRKRDRERRRKEKET-NRNRDREKQTEIERDRERE-KQKGRERERDRGRERERDRDREKE 152
+ K + E ET +R R+R ++T+ ERDR +E K + R ERDR R+RER+R+R+++
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 153 RERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
RER+ + DR+G+R+ E ER+RDR+RE ++ER+ ER+ DR +T++ER++Q +RE +R R
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 213 TQTERQRETDREGE--RETDRRRERQ--RDRDRGKER---DRERDRKEERKKERKKERKK 265
+ E+Q+E RE + RETDR RERQ R+R+ G+ER DR R+R+ ERK+ER+++R+
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
Query: 266 ERKEK----KKEEKRREDKKR 282
+ +E+ ++E +R D+KR
Sbjct: 182 KERERHTDMERERQRETDRKR 202
Score = 166 bits (419), Expect = 3e-41
Identities = 88/198 (44%), Positives = 137/198 (69%), Gaps = 20/198 (10%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
K++ +DR ERDR R++ ER+R+R RDRER EK+T+R +R+++ E +RDR+RE
Sbjct: 35 KESKTEDRHSERDRQRDR---ERNRERDRDRER---EKQTDREGERQRERERDRDRQRET 88
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
++ R++ER+ R E DR+R+K++ER E ER RDREREKQKE ER
Sbjct: 89 ERERDKERETDRHTETDRERQKQKER------------EMERVRDREREKQKEMGRERQT 136
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER 249
DR+ D E+ER+ + +RE R+RKT+ +R RE +RE +RE +R+RE ++R+R + +RER
Sbjct: 137 DRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE-TKERERHTDMERER 194
Query: 250 DRKEERKKERKKERKKER 267
R+ +RK++R++E ++ER
Sbjct: 195 QRETDRKRDRQRESERER 212
Score = 154 bits (389), Expect = 9e-38
Identities = 82/184 (44%), Positives = 130/184 (70%), Gaps = 11/184 (5%)
Query: 110 NRNRDREKQTEIER-DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETE 168
++ R TE E DR+RE+++ +RERDR +E + + DR ER+RQ +++R+ +R+ +
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRD 61
Query: 169 TERERDREREKQKERETERDRDRQRDTEKER--ERQTDR--ERDRQRKTQTERQRE--TD 222
ERE+ +RE +++RE ERDRDRQR+TE+ER ER+TDR E DR+R+ Q ER+ E D
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 223 REGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKE---RKKERKEKKKEEKRRED 279
RE E++ + RERQ DR+ +ER+R+ +R+ E +ERK E R++ER+ K++ E++RE
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
Query: 280 KKRK 283
K+R+
Sbjct: 182 KERE 185
Score = 149 bits (376), Expect = 3e-36
Identities = 88/210 (41%), Positives = 137/210 (65%), Gaps = 17/210 (8%)
Query: 25 SLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDR 83
S T H H+ T+ + + R R ++ES + + D + +R+R+RDR
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 84 VREKT---------EKERDRDRKRDRERRR-KEKETNRNR--DREKQTEIERDREREKQK 131
REK E+ERDRDR+R+ ER R KE+ET+R+ DRE+Q + ER+ ER + +
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETE-RERDREREKQKERETERD-- 188
RE++++ GRER+ DR+ ++ERERQ E++R+ RE +TE R R+RERE+++ERE +R+
Sbjct: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182
Query: 189 -RDRQRDTEKERERQTDRERDRQRKTQTER 217
R+R D E+ER+R+TDR+RDRQR+++ ER
Sbjct: 183 ERERHTDMERERQRETDRKRDRQRESERER 212
Score = 69.7 bits (169), Expect = 3e-12
Identities = 39/100 (39%), Positives = 63/100 (63%), Gaps = 8/100 (8%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREK-TEKER---DRDRKRDRERRRKEKE 108
R+ +E + +G+ + DR+RER RE+ T +ER DR R+R+RER+R+ +
Sbjct: 118 RVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERER 177
Query: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD 148
++RE+ T++ER+R+RE +R+RDR RE ER+RD
Sbjct: 178 KRETKERERHTDMERERQRET----DRKRDRQRESERERD 213
Score = 52.0 bits (123), Expect = 6e-07
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Query: 48 DFSRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDRVREKTEKERDRDRKRDRERRRKE 106
D R +++ R G+ K D +R+RER R RE+ + ++R+R D ER R +
Sbjct: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERER-Q 195
Query: 107 KETNRNRDREKQTEIERD 124
+ET+R RDR++++E ERD
Sbjct: 196 RETDRKRDRQRESERERD 213
Score = 48.1 bits (113), Expect = 9e-06
Identities = 27/63 (42%), Positives = 42/63 (66%), Gaps = 4/63 (6%)
Query: 226 ERET-DRRRERQRDRDRGKERDRERDRK-EERKKERKKERKKERKEKKKEEKRREDKKRK 283
E ET DR+RER+R+ DR ERDR ++ K E+R ER ++R +ER ++ ++ RE + +
Sbjct: 13 ETETMDRQRERRRETDR--ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70
Query: 284 WGE 286
GE
Sbjct: 71 EGE 73
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 185 bits (469), Expect = 5e-47
Identities = 107/265 (40%), Positives = 159/265 (60%), Gaps = 26/265 (9%)
Query: 45 IPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRR 104
+P SRG GSQ S H + ERDR E+ +++ RD +R
Sbjct: 570 LPEKGSRGSRGSQIDSHSSN-SNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE 628
Query: 105 KEKETNRNRDRE---------KQTEIERDREREKQK---------GRERERDRGRERERD 146
+++ NR RD+ + E+ERD RE+++ R RERDR RER+R+
Sbjct: 629 RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE 688
Query: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206
R+RE+ERER +++R+ +RE E ER R+RERE++KER+ ERDRDR D E+ERER+ DRE
Sbjct: 689 RERERERER--DREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE 746
Query: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK----KERKKE 262
++R+R+ + ER+RE +RE ERE +R RER+R R+R KER+R+RD +++ K + K+E
Sbjct: 747 KERERERE-ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKRE 805
Query: 263 RKKERKEKKKEEKRREDKKRKWGEG 287
+E + + R+ KKR EG
Sbjct: 806 EIREDRNPRDGHDERKSKKRYRNEG 830
Score = 170 bits (430), Expect = 2e-42
Identities = 93/215 (43%), Positives = 145/215 (67%), Gaps = 13/215 (6%)
Query: 71 DADGDDRQRER--DRV---REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
+ + D+R+ ER DRV R++ +ERDR+R+RDRER R E+E R+R+REK+ E+ER+R
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERER-ERERERDREREKERELERER 711
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
RE+++ RE+ERDR R+R+RD DRE+ERER+ +++++ +RE E ERER+RERE+++ERE
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKERERERE-ERERERERERERERER 770
Query: 186 ERDRDRQRDTEKERERQTD-RERDRQRKTQTERQRE--TDREGERETDRRRERQRDRDRG 242
ER+R+R R+ +KERERQ D ++D+ R + E++ E DR D R+ ++R R+ G
Sbjct: 771 ERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG 830
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
R+ +R++E + K EK R
Sbjct: 831 SPSPRQ---SPKRRREHSPDSDAYNSGDDKNEKHR 862
Score = 168 bits (426), Expect = 4e-42
Identities = 87/201 (43%), Positives = 135/201 (67%), Gaps = 6/201 (2%)
Query: 74 GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
G + + ERD RE+ +R DR R+ R +E++ R RDRE++ E ER+R+RE++K R
Sbjct: 649 GRNDELERDERREERRVDRVDDR---RDERARERDRERERDRERERERERERDREREKER 705
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E ER+R RERER+ REKER+R+ ++DRD RE E ERERDRE+E+++ERE ER+R+R+R
Sbjct: 706 ELERERARERERE--REKERDRERDRDRDHDRERERERERDREKERERERE-ERERERER 762
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKE 253
+ E+ERER+ +RER R+R + ERQR+ + + + DRR +R+ R+ RD +RK
Sbjct: 763 ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKS 822
Query: 254 ERKKERKKERKKERKEKKKEE 274
+++ + + K++ E
Sbjct: 823 KKRYRNEGSPSPRQSPKRRRE 843
Score = 135 bits (340), Expect = 4e-32
Identities = 88/265 (33%), Positives = 144/265 (54%), Gaps = 42/265 (15%)
Query: 58 ESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDR-DRKRDRERRRKEKETNRNRDRE 116
E RS+G +++ + + E R ++E DR R R R EK + +R +
Sbjct: 524 EESRSYGRNHLREESSRTEIRNE-SRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQ 582
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR- 175
+ + + R +R R ERD +R++ R+ E+ R G+R+ RERD+
Sbjct: 583 IDSHSSNSNYHDSWETRSSYPERDRYPERD-NRDQARDSSFER-RHGERDRRDNRERDQR 640
Query: 176 --------------EREKQKE---------------RETERDRDRQRDTEKERERQTDRE 206
ER++++E RE +R+R+R R+ E+ERER+ DRE
Sbjct: 641 PSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRE 700
Query: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR-------KEERKKER 259
R+++R+ + ER RE +RE E+E DR R+R RD DR +ER+RERDR +EER++ER
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760
Query: 260 KKERKKER-KEKKKEEKRREDKKRK 283
++ER++ER +E+++E R DK+R+
Sbjct: 761 ERERERERERERERERARERDKERE 785
Score = 126 bits (316), Expect = 3e-29
Identities = 80/237 (33%), Positives = 139/237 (58%), Gaps = 29/237 (12%)
Query: 76 DRQRERDRVREKT---EKERDRDRKRDRERRR-KEKETNRNRDREKQTEIERDREREKQK 131
+R+RERDR REK E+ER R+R+R+RE+ R +E++ +R+ DRE++ E ERDRE+E+++
Sbjct: 692 ERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERER 751
Query: 132 GRE-------RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE-R 183
RE RER+R RERER+R+R +ER+++ E+ RD + + ++ RD REK++E R
Sbjct: 752 EREERERERERERERERERERERERARERDKERERQRDWE---DKDKGRDDRREKREEIR 808
Query: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR---DRD 240
E RD + + ++ + + ++ + R+ D + D + E+ R
Sbjct: 809 EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVV 868
Query: 241 RGKE----------RDRE-RDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
R +E DR+ R ++E+RK ERK+ ++ +++ KE+ DK+R+ E
Sbjct: 869 RPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTE 925
Score = 105 bits (263), Expect = 4e-23
Identities = 65/217 (29%), Positives = 114/217 (52%), Gaps = 9/217 (4%)
Query: 67 QAHKDADGD-DRQRERDRVREKT-EKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
+ K+ D + DR R+ DR RE+ E++R+++R+R+RE R +E+E R R+RE++ E ER
Sbjct: 718 EREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERA 777
Query: 125 REREKQKGRER---ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
RER+K++ R+R ++D+GR+ DR ++E R+ RDG E ++++ E
Sbjct: 778 RERDKERERQRDWEDKDKGRD---DRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSP 834
Query: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
+ +R R+ D++ E+ R Q T+ R+ R ++ DR
Sbjct: 835 RQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDR 894
Query: 242 GKERDRERDRKEERK-KERKKERKKERKEKKKEEKRR 277
ER R EE++ KE+ K+R++ + E R
Sbjct: 895 KPERKESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Score = 88.6 bits (218), Expect = 6e-18
Identities = 64/221 (28%), Positives = 106/221 (47%), Gaps = 9/221 (4%)
Query: 65 LGQAHKDADGDDRQ-RERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
+ Q + G +R R R ++ R D + RK + +RDREK +E
Sbjct: 1184 MDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEI 1243
Query: 124 DREREKQKGRERERDRGRERERDR-DREKERERQTEKDRDGQRETETERERDREREKQKE 182
ER+ + + + + R DR D R++ + D Q + + R+R ++++
Sbjct: 1244 TGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERD 1303
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR- 241
R E DR+R+R+ R+R+ DR+ D+ +R R +RE ERE D+RR+ R+R+R
Sbjct: 1304 RY-EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERL 1362
Query: 242 ---GKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
ERDR+RDR +R E + +R E K E + D
Sbjct: 1363 ISDSVERDRDRDR--DRTFESSQIESVKRCEAKLEGEHERD 1401
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/246 (30%), Positives = 115/246 (46%), Gaps = 21/246 (8%)
Query: 46 PLDFSRGR-LGSQESPRSWGLGQAHKDAD------GDDRQRERDRVREKTEKERDRDRKR 98
P+D R LGS S RS G+ ++ GDD Q R RV ++R++ +
Sbjct: 1183 PMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDD-QSGRKRVLHSGSRDREKTKSL 1241
Query: 99 DRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTE 158
+ RK + D+ K+ E R ++Q R R + DR+ +
Sbjct: 1242 EITGERKSRI-----DQLKRGEPSRSTSSDRQDSRSHS---SRRSSPESDRQVHSRSGSF 1293
Query: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
RD +E + E DRERE+++ +R+ DR D + R R DR R+R+R+ + +++
Sbjct: 1294 DSRDRLQERD-RYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKR 1352
Query: 219 RETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK-ERKKERKKERK-EKKKEEKR 276
R+ DRE ER ER RDRDR +R E + E K+ E K E + ER E +
Sbjct: 1353 RDLDRERERLISDSVERDRDRDR--DRTFESSQIESVKRCEAKLEGEHERDLESTSRDSL 1410
Query: 277 REDKKR 282
DK+R
Sbjct: 1411 ALDKER 1416
Score = 81.3 bits (199), Expect = 9e-16
Identities = 72/273 (26%), Positives = 116/273 (42%), Gaps = 70/273 (25%)
Query: 73 DGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKG 132
DG DR+ RD R++ E RD + RE R ++T +RD + ++G
Sbjct: 454 DGRDRRDARD-TRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREG 512
Query: 133 RE--RERDRGRERERD--RDREKERERQTEKDRDGQRETETERERDR------------- 175
R+ R+ D E R R+ +E +TE + + E+ +E DR
Sbjct: 513 RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572
Query: 176 ---------EREKQKERETERDRDRQRDTEKERERQTDRE-RDRQRKTQTERQRETDREG 225
+ + D R + ER+R +R+ RD+ R + ER R G
Sbjct: 573 KGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER-----RHG 627
Query: 226 ERETDRRRERQRDR----------------------------------DRGKERDRERDR 251
ER DRR R+RD+ +R +ERDRER+R
Sbjct: 628 ER--DRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Query: 252 KEERKKERKKERKKER-KEKKKEEKRREDKKRK 283
ER++ER++ER +ER KE++ E +R +++R+
Sbjct: 686 DRERERERERERDREREKERELERERARERERE 718
Score = 79.3 bits (194), Expect = 4e-15
Identities = 63/224 (28%), Positives = 104/224 (46%), Gaps = 16/224 (7%)
Query: 69 HKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER----- 123
H + ++ D+ R + +R R R + +R + Q+ +R
Sbjct: 1172 HVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSG 1231
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETER---ERDREREKQ 180
R+REK K E +R + D+ + E R T DR R + R E DR+ +
Sbjct: 1232 SRDREKTKSLEITGER--KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSR 1289
Query: 181 KERETERDRDRQRDT-EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
RDR ++RD E +RER+ +R RQR E R+ D++ R DR R R+R+R
Sbjct: 1290 SGSFDSRDRLQERDRYEHDRERERERRDTRQR----EWDRDADKDWPRNRDRDRLRERER 1345
Query: 240 DRGKERDRERDRKEERKKERKKERKKER-KEKKKEEKRREDKKR 282
+R +++ R+ DR+ ER ER ++R +++ E + E KR
Sbjct: 1346 ERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKR 1389
Score = 78.2 bits (191), Expect = 8e-15
Identities = 72/276 (26%), Positives = 117/276 (42%), Gaps = 74/276 (26%)
Query: 79 RERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERD 138
R R +REK + +R + R + ++T RDREK + ER+ E+++ R+ D
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 139 R----GRERERDRDREKERERQTEKD-------RDGQRETETERE-RD----REREKQKE 182
R GR+R RD RE + +D RD R+T+ R+ RD R+ ++
Sbjct: 450 REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERE--TDRR-RERQR-- 237
RE RD R+ DT E R R R+ ++TE + E+ E E DR R R R
Sbjct: 510 REG-RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVP 568
Query: 238 -----------------------------------DRDRGKERDR--------------E 248
+RDR ERD E
Sbjct: 569 ELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE 628
Query: 249 RDRKEERKKERKKE---RKKERKEKKKEEKRREDKK 281
RDR++ R+++++ R + R ++ + ++RRE+++
Sbjct: 629 RDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Score = 77.0 bits (188), Expect = 2e-14
Identities = 61/241 (25%), Positives = 111/241 (46%), Gaps = 28/241 (11%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
+R RERD+ RE+ D+D+ RD +RR K +E +R+ + + ++R + +G
Sbjct: 775 ERARERDKERERQRDWEDKDKGRD-DRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 136 ERD---RGRERERDRDREKERERQTEKDR---------DGQRETETERERDRE-REKQKE 182
R R RE D D + + EK R + + + + DR+ R K+++
Sbjct: 834 PRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED 893
Query: 183 RETERDRDRQRDTE---KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
R+ ER +R E KE+ D++R++ ++ R R D G +++ R R
Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953
Query: 240 DRGKERDRERDRKEERKK-----------ERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
D K++ + + + ++KK E E + KK ++K+ +KKRK +G
Sbjct: 954 DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGD 1013
Query: 289 S 289
S
Sbjct: 1014 S 1014
Score = 70.1 bits (170), Expect = 2e-12
Identities = 53/186 (28%), Positives = 85/186 (45%), Gaps = 9/186 (4%)
Query: 102 RRRKEKETNRNRDREKQTEIERDREREKQK-GRERERDRGRERERDRDREKERERQTEKD 160
+R++ +R+ REK D ER Q R ER +RDR+++ ER+ E+D
Sbjct: 383 QRKQSPPRHRSPMREKG---RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQD 439
Query: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE-RDRQRKTQTERQR 219
+ R+ +RE R+++ R+T RDR RD+ R+ + RE RD R T+ R
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDT-RDRRELRDS---RDMRDSREMRDYSRDTKESRDP 495
Query: 220 ETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
R D R RD R ++ E R R R++ + E + + + E R E
Sbjct: 496 RDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEI 555
Query: 280 KKRKWG 285
+ + G
Sbjct: 556 RNDRMG 561
Score = 69.3 bits (168), Expect = 4e-12
Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 23/211 (10%)
Query: 93 DRDRKRDRERRRKEK-ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
+ D R R R EK ET + Q D++R G R +R R R
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRS-NRSHTSGRLRSPSN 1211
Query: 152 ERERQTEKDRDGQRETETERERDREREKQKERETER----------------DRDRQRDT 195
+ ++ D+ G++ RDRE+ K E ER DRQ D+
Sbjct: 1212 DSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQ-DS 1270
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREGER---ETDRRRERQRDRDRGKERDRERDRK 252
R++ E DRQ +++ DR ER E DR RER+R R +E DR+ D+
Sbjct: 1271 RSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKD 1330
Query: 253 EERKKERKKERKKERKEKKKEEKRREDKKRK 283
R ++R + R++ER E++++++R D++R+
Sbjct: 1331 WPRNRDRDRLRERER-ERERDKRRDLDRERE 1360
Score = 54.7 bits (130), Expect = 9e-08
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 24/153 (15%)
Query: 75 DDRQRERDRVREKT-EKERDRDRKRDRERRR---KEKETNRNRDREKQTEIERDREREKQ 130
D RQRE DR +K + RDRDR R+RER R K ++ +R R+R +ERDR+
Sbjct: 1317 DTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRD---- 1372
Query: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR- 189
RDRDR E Q E + + + E E ERD E + +++R
Sbjct: 1373 --------------RDRDRTFE-SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERM 1417
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETD 222
D+ + + E ER + + + D
Sbjct: 1418 DKDLGSVQGFEETNKSERTESLEAGDDESKLDD 1450
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 13/171 (7%)
Query: 102 RRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR 161
RR E+ T R+R K + D E +K+ E +E R R REKE + T+
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITK--- 131
Query: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR-KTQTERQRE 220
+R E+E E+ E ET RD D + + E RQ+ + + + +
Sbjct: 132 --ERTPESE-------EENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQ 182
Query: 221 TDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271
+ E E ++E + R K RK + +RK K KK
Sbjct: 183 ENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKK 233
Score = 45.4 bits (106), Expect = 6e-05
Identities = 46/250 (18%), Positives = 108/250 (43%), Gaps = 25/250 (10%)
Query: 59 SPRSWGLGQAHKDAD----GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD 114
SPR G ++ + GD R+R +++ ++ + + R+ + RKE R+R+
Sbjct: 64 SPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE 123
Query: 115 RE--KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
+E K T+ E+ E RD + + D E + ++ + + + E+E
Sbjct: 124 KEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQE 183
Query: 173 RDRERE-----KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER 227
+RE K+ E R + + ++ + R+ + + +++ R+T
Sbjct: 184 NMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSP 243
Query: 228 ETDRRRERQRDRDRGK-----------ERDRERDRKEERK---KERKKERKKERKEKKKE 273
D++R + ++ + K D +K + K K+R +E+ ++ K++ ++
Sbjct: 244 LLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRD 303
Query: 274 EKRREDKKRK 283
+R+ +K+ K
Sbjct: 304 FERQREKRDK 313
Score = 43.5 bits (101), Expect = 2e-04
Identities = 42/194 (21%), Positives = 78/194 (40%), Gaps = 7/194 (3%)
Query: 62 SWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI 121
S L +H D R +E DR E+ E R R E+ KEK ++ ++ RE+ +
Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSR-----RYEEQELKEKVSSVDKQREQTEIL 927
Query: 122 ERDREREKQ-KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
E R R + G + DR +R D K++ + +K ++E + ER
Sbjct: 928 ESSRMRAQDIIGHHQSEDR-ETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTS 986
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD 240
++ + + Q+ E++R+ + + +Q + R +E +
Sbjct: 987 EDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMC 1046
Query: 241 RGKERDRERDRKEE 254
GK E +K+E
Sbjct: 1047 NGKNGILEDSQKKE 1060
Score = 32.3 bits (72), Expect = 0.50
Identities = 26/149 (17%), Positives = 67/149 (44%), Gaps = 16/149 (10%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
+ES R + + + D+QRE+ + E + R R + ++ +
Sbjct: 899 KESSRRYEEQELKEKVSSVDKQREQTEILESS-------------RMRAQDIIGHHQSED 945
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRD--GQRETETERERD 174
++T +R + K+K + +++ +++E D E+ T +D ++ + ++ +
Sbjct: 946 RETS-DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIE 1004
Query: 175 REREKQKERETERDRDRQRDTEKERERQT 203
++R+K K D + + ++K+R +T
Sbjct: 1005 KKRKKSKGDSDISDEEAAQQSKKKRGPRT 1033
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 184 bits (467), Expect = 8e-47
Identities = 115/248 (46%), Positives = 152/248 (61%), Gaps = 51/248 (20%)
Query: 44 TIPLDFSRGRLGSQESPRSWGLGQAHKDADGD-----------------DRQRERDRVRE 86
TI FS+ L Q P SW L + D D +RQRER+R R+
Sbjct: 14 TITESFSQLLL--QTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRK 71
Query: 87 KT-----------EKERDRDRKRDRERRR-KEKETNRNR--DREKQTEIERDREREKQKG 132
+ EK+RDR RKRDRER+R ++++ R R DR+++TE ER ERE+Q+
Sbjct: 72 RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRD 131
Query: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRET-ETERERDREREKQKERETERDRDR 191
R+RE+DR R+R+R+ +K+RE +TEKDRD +RE ETER RDRERE+QK+RET RDRDR
Sbjct: 132 RKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDR 191
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
+R EKE DRERDR DR+ ERE DR RER+ RDR KERDRER R
Sbjct: 192 ERQREKE-----DRERDR------------DRQKEREKDRYRERETGRDRDKERDRERQR 234
Query: 252 KEERKKER 259
+++R +++
Sbjct: 235 EKDRDRQK 242
Score = 140 bits (353), Expect = 1e-33
Identities = 67/171 (39%), Positives = 121/171 (70%), Gaps = 7/171 (4%)
Query: 115 REKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD 174
RE++ + ER+R+R++ K R RE+DR E++RDR R+++RERQ +DRD +RE +R+R+
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 175 REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
E E+Q+ERE +RDR R++D E++R+R+ ++DR+ +T+ +R RE + GE E
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM-GETE------ 170
Query: 235 RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWG 285
R RDR+R +++ RE R +R+++R+KE ++ ++++KE ++ ++R+ G
Sbjct: 171 RYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
Score = 53.9 bits (128), Expect = 2e-07
Identities = 20/56 (35%), Positives = 43/56 (76%)
Query: 231 RRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
R RERQR+R+R ++R +ER R+++R+ E+ ++R+++R +++ + R+ K+ +WG+
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 182 bits (461), Expect = 4e-46
Identities = 89/216 (41%), Positives = 148/216 (68%), Gaps = 7/216 (3%)
Query: 69 HKDADGDDRQRERDRVR-EKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER 127
HK + + ++E++R EK +ER+R+R+R+RERR +E+E R R+REK+ E ER+RER
Sbjct: 288 HKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER 187
++ + R +ERDR R+RERDRD ++RER +++++D R E R+R+RERE+++ERE ER
Sbjct: 348 DRDRDRTKERDRDRDRERDRD--RDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Query: 188 DRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
+R+R+R+ E+ERER+ +RER++ +K R RE D E E + + R+++ +
Sbjct: 406 EREREREREREREREREREREKDKK----RDREEDEEDAYERRKLERKLREKEAAYQERL 461
Query: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
+ ERKK R+ E++ ER+E+++ E +E K+ K
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497
Score = 172 bits (436), Expect = 3e-43
Identities = 88/221 (39%), Positives = 145/221 (65%), Gaps = 7/221 (3%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
++ + + R+RER+R RE+ +ER+R+R+R+RER EKE R R+RE+ + +R +ER++
Sbjct: 303 QEIEKERRERERERERERERRERERERERERER---EKEKERERERERDRDRDRTKERDR 359
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
+ RER+RD R+RER DR K+R R EK RD +RE E ERER+RERE+++ERE ER+R
Sbjct: 360 DRDRERDRD--RDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERER 417
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ--RDRDRGKERDR 247
+R+R+ E+E++++ DRE D + + + RE E R + R+R + +E ++
Sbjct: 418 EREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEK 477
Query: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
E +R+EER++E KE K+ ++ + + R+D K G +
Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518
Score = 169 bits (427), Expect = 3e-42
Identities = 91/244 (37%), Positives = 158/244 (64%), Gaps = 32/244 (13%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRER---RRKEKETNRNRDREKQTEIERDREREKQKG 132
+R+RER+R RE+ E+ER+R+R+R+RE+ R +E+E +R+RDR K+ + +RDRER++ +
Sbjct: 311 ERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRD 370
Query: 133 RER------ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186
RER +R R RE+ RDR+RE+ERER+ E++R+ +RE E ERER+RERE+++E++ +
Sbjct: 371 RERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Query: 187 RDRDRQRDTEKERERQTDRERDRQRKTQ----------TERQRETDREGERETDRRRERQ 236
RDR+ + ER + + R+++ Q ++ RE ++E ERE +RRRE
Sbjct: 431 RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490
Query: 237 RDRDRGKE--RDRERDRK----------EERKKERKKERKKERKEKKKEEKRRED-KKRK 283
++ R KE D + DR ++R ++R+KE + + +++K+E++ E+ ++R
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRL 550
Query: 284 WGEG 287
EG
Sbjct: 551 LAEG 554
Score = 161 bits (408), Expect = 5e-40
Identities = 83/193 (43%), Positives = 129/193 (66%), Gaps = 14/193 (7%)
Query: 88 TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDR 147
T+++ + + +R +E ++ RD K+ E E+ ++ ++++ E+ER RER+R
Sbjct: 260 TKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-----RERER 314
Query: 148 DREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRER 207
+RE+ERER RE E ERER+REREK+KERE ER+RDR RD KER+R DRER
Sbjct: 315 ERERERER---------REREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Query: 208 DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER 267
DR R + R DR RE R RER+R+R+R +ER+RER+R+ ER++ER++ER++ER
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425
Query: 268 KEKKKEEKRREDK 280
++ KK ++ +++
Sbjct: 426 EKDKKRDREEDEE 438
Score = 143 bits (361), Expect = 2e-34
Identities = 79/238 (33%), Positives = 145/238 (60%), Gaps = 33/238 (13%)
Query: 75 DDRQRERDR---------VREKTEKERDRDRKRDRERRRKEKETNRNRDR---------- 115
D+ + RD+ +RE + + ++ D R+K+KE + R
Sbjct: 197 DEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPY 256
Query: 116 -----EKQTEIERDREREKQKGRE--RERDRGRERERDRDREKERERQTEKDRDGQRETE 168
E IE + ++ RE + RD ++ E ++ ++++ ++ EK+R RE E
Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER---RERE 313
Query: 169 TERERDRER-EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER 227
ERER+RER E+++ERE ER+R+++++ E+ERER DR+R ++R +R+R+ DR+ ER
Sbjct: 314 RERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRER 373
Query: 228 ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER---KEKKKEEKRREDKKR 282
+DR ++R R R++ ++R+RER+R+ ER++ER++ER++ER +E+++E +R +DKKR
Sbjct: 374 SSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Score = 133 bits (334), Expect = 2e-31
Identities = 81/244 (33%), Positives = 140/244 (57%), Gaps = 32/244 (13%)
Query: 70 KDADGD-DRQRERDRVREKT-----EKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
K+ D D DR+R+RDR RE++ ++ R R++ RDRER R E+E R R+RE++ E ER
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER-ERERERERERERERERER 413
Query: 124 DREREKQKGRERERDRGRERERDR----DREKERERQTEKDRDGQRETETERERDREREK 179
+RERE+++ RERE+D+ R+RE D +R K + EK+ Q + R+R++ +
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTR 473
Query: 180 QKERETERDRDRQRDTEKERER--------QTDRERDRQRKTQTERQRETDREGERETDR 231
+ E+E ER+ +R+R+ KE +R DR+ + + ++R DRE E E D
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD- 532
Query: 232 RRERQRDRDRGKE------------RDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
R+R+R+++ +E D E R E+ + R++ + K+ E ++EE+ +++
Sbjct: 533 ERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592
Query: 280 KKRK 283
K+ K
Sbjct: 593 KEEK 596
Score = 116 bits (290), Expect = 3e-26
Identities = 75/245 (30%), Positives = 137/245 (55%), Gaps = 20/245 (8%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRER---RRKEK 107
R R + S R+ ++ + + +R+RER+R RE+ E+ER+R+R+R+RER R +E+
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERER-ERERERERERERERERERERER 425
Query: 108 ETNRNRDREKQTEIERDREREKQKGRERE------------RDRGRERERDRDREKERER 155
E ++ RDRE+ E +R + ++K RE+E R+R + RE +++ E+E ER
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 156 QTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT 215
+ E ++ +R E + D +R+ K + R RD EKE E +R+R R+++
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD-ERDRKREKEELE 544
Query: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEK 275
E ++ EG + D +R ++ ER R+ K+E + E ++E K+E++EK++E
Sbjct: 545 EIRQRLLAEGHPDPDAELQRM---EQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPM 601
Query: 276 RREDK 280
E++
Sbjct: 602 EEEEE 606
Score = 55.1 bits (131), Expect = 7e-08
Identities = 61/230 (26%), Positives = 91/230 (39%), Gaps = 90/230 (39%)
Query: 48 DFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKT-EKERDRDRKRDRE----- 101
D SR R S++ R + + +R+RER+R RE+ E+ER++D+KRDRE
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 102 --------RRRKEKETNRN--------RDREKQTEIERDREREKQKGRE----------- 134
R+ +EKE R+R+K E E++ ERE+++ RE
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEF 499
Query: 135 ---------------------RERDRGRERE---RDRDREKER----------------- 153
R RDR +E E RDR REKE
Sbjct: 500 LEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPD 559
Query: 154 ------ERQTEKDRDGQ----------RETETERERDREREKQKERETER 187
E++ E+ R Q E + E+E RE ++E E E+
Sbjct: 560 AELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Score = 45.4 bits (106), Expect = 6e-05
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 23/129 (17%)
Query: 71 DADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQ 130
D D DD + R +K + RDR+++ + + ERDR+REK+
Sbjct: 504 DDDRDDPKYYRGSALQK--RLRDREKEMEAD--------------------ERDRKREKE 541
Query: 131 KGRERERDRGRERERDRDREKER-ERQTEKDRDGQRETETERERDREREKQKERETERDR 189
+ E + E D D E +R E++ E+ R Q + E E E + E +++KE + E
Sbjct: 542 ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPM 601
Query: 190 DRQRDTEKE 198
+ + + E++
Sbjct: 602 EEEEEPEQK 610
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 149 bits (376), Expect = 3e-36
Identities = 84/264 (31%), Positives = 147/264 (55%), Gaps = 30/264 (11%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDRVREKT-----EKERDRDRKRDRERR 103
S+ R S+ R H+ + R R++DR R K+ K R+R + R R
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373
Query: 104 RKEKETNRNRDREKQTEIERDRE--REKQKGRERERDRGRERERDRDREKERERQTEKDR 161
R +++ R + +EK+ E+DRE RE++K RE+E++RG+ ++RD++REK+RE+ EKDR
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 433
Query: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERE------------------RQT 203
+ +RE E E++RD+E+EK++++E ER++DR ++ +++R+ R +
Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Query: 204 DRERDRQRKTQTERQRETDREGERETDR----RRERQRDRDRGKERDRERDRKEERKKER 259
RER R+R + R T + +R++ R R ++D+ R KERD +R+E +
Sbjct: 494 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 553
Query: 260 KKERKKERKEKKKEEKRREDKKRK 283
++ +R K+K EK K K
Sbjct: 554 MRKSSNDRDGKEKLEKNSTSLKEK 577
Score = 149 bits (376), Expect = 3e-36
Identities = 81/259 (31%), Positives = 143/259 (55%), Gaps = 20/259 (7%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
S+ R S RS + + R + R+R R+ + RD+++D + KEKE
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIKEKER 389
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
+ +DREK+ E E++RE+EK++G+ ++RD+ RE++R++D+EK+RER+ EK+ + R+ E
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 170 ERERDREREKQKERETERDRDRQRDTEKE----------RERQTDRERDRQRKTQTERQR 219
E+E+D+E+E++K+R E D R++D + R R + RER R+R + R
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 220 ETDREGERETDR----RRERQRDRDRGKERD-----RERDRKEERKKERKKERKKERKEK 270
T + +R++ R R ++D+ R KERD RER+R +K KE+ EK
Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569
Query: 271 KKEEKRREDKKRKWGEGIS 289
+ ++ ++ +S
Sbjct: 570 NSTSLKEKEHNKEPDSSVS 588
Score = 140 bits (353), Expect = 1e-33
Identities = 64/214 (29%), Positives = 125/214 (58%), Gaps = 2/214 (0%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTE-KERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
+ A + G +R+ R R T K R + R +R + K +R+ +R + + +R
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 348
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
R + K R + R+R + R R R+K ++ + EK ++ +R E +RE++REREK++E+
Sbjct: 349 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR-EKIKEKERVKEKDREKEREREKEREK 407
Query: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243
E ER +++ RD E+E++R+ D+E+DR+R+ + E +++ D+E E+E D+ +ER++DR +
Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467
Query: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
+ R++D+K ++ R ++ +RR
Sbjct: 468 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Score = 140 bits (352), Expect = 2e-33
Identities = 79/247 (31%), Positives = 130/247 (52%), Gaps = 36/247 (14%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
G++++ G R R + R ++ R R + + R R NR+R R+K +
Sbjct: 298 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH---NRSRSRQKDRRRSKSP 354
Query: 126 EREKQKGRERERDRGRERERD-----RDREKERERQTEKDRDGQRETETERERDREREKQ 180
+++ K RER + R R RD R++ KE+ER EKDR+ +RE E ERE+++ER K
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE------ 234
K+R+ ER++DR++D EK+RER+ ++E ++ R E+++E D+E ERE DR +E
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDR--DKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 235 --------------RQRDRDRGKERDRERDRKEERKK------ERKKERKKERKEKKKEE 274
+R R +ER R R R R +RK R + + K++
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Query: 275 KRREDKK 281
K+RE ++
Sbjct: 533 KKREKER 539
Score = 133 bits (335), Expect = 2e-31
Identities = 72/242 (29%), Positives = 129/242 (53%), Gaps = 20/242 (8%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRER-----RRKEKETNR 111
+ + R G ++H + + R + K R R R R R R K R
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 112 NRDREKQTEIERDREREKQKG-RERERDRGRERERDRDREKER--ERQTEKDRDGQRETE 168
++ RE++ R R+K+K RE+ +++ R +E+DR++E+ER ER+ EK+R ++ +
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Query: 169 TERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ--RKTQTERQRETDRE-- 224
ERE+DRE++K+K+RE ER+++ ++D +KE+E++ D+E++R+ R + + +R+ D++
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
Query: 225 --------GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
R RER+R R R R + +RK R + K+ KK EK
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Query: 277 RE 278
R+
Sbjct: 539 RD 540
Score = 132 bits (332), Expect = 4e-31
Identities = 65/199 (32%), Positives = 125/199 (62%), Gaps = 13/199 (6%)
Query: 89 EKERDRDRKRDRER---RRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER 145
E + +RK R R R K + ++++ R K+++ + R R + R R++DR R +
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQ-SKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 146 DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR 205
+ R K RER+ + R R+ +R+ RE+ K+KER E+DR EKERER+ +R
Sbjct: 355 HKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKERVKEKDR------EKEREREKER 405
Query: 206 ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKK 265
E++++R +R +E +++ E++ ++ RER+R+++ K+RD+E++++++++KER+K+R K
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Query: 266 ERKEKKKEEKRREDKKRKW 284
E EK+K++K+ R +
Sbjct: 466 EIDEKRKKDKKSRTPPRSY 484
Score = 121 bits (304), Expect = 6e-28
Identities = 68/222 (30%), Positives = 123/222 (55%), Gaps = 14/222 (6%)
Query: 70 KDADGDDRQRERDRVREKT-EKERDRDRKRDRERRR-------KEKETNRNRDREKQTEI 121
K D ++ +E++RV+EK EKER+R+++R++E+ R KE+E +R +D+EK E
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435
Query: 122 ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
ER++E EK + +E+E+++ +E+ER++DR KE + + +KD+ + + R R +
Sbjct: 436 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 495
Query: 182 ERETERDRDRQRD--TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
ER R R R T K +R++ R + + + +++RE +R+ RRER+R
Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD---HISERRERERST 552
Query: 240 D-RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
R DR+ K E+ KE++ ++ K +DK
Sbjct: 553 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594
Score = 118 bits (296), Expect = 5e-27
Identities = 60/203 (29%), Positives = 121/203 (59%), Gaps = 12/203 (5%)
Query: 90 KERDRDRKRDRERRRK-----EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
KE + KR RE + E E+ ++ +R+ R + + + R R R +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 331
Query: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE---KERER 201
+ R R R R +KDR +R ++R + RE++K R RD+++DT KE+ER
Sbjct: 332 KHRSRSHNRSRSRQKDR--RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKK 261
+++R+++R+ + ER++E +R ++ D+ RE+ R++D+ K+R+RER+++ E+ ++++K
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 262 ERKKER-KEKKKEEKRREDKKRK 283
E+++++ KE++K+ + D+KRK
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRK 472
Score = 94.7 bits (234), Expect = 8e-20
Identities = 58/193 (30%), Positives = 106/193 (54%), Gaps = 10/193 (5%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRR---KEKETNRNRDREKQTEIERDREREKQKG 132
D++RE+DR ++K EK+R+R+R+++ E+ R KEKE ++ ++REK E D +R+K K
Sbjct: 418 DKEREKDREKDK-EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK- 475
Query: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
+ R R R R R RER+ + R R T + R+ + + +D++
Sbjct: 476 KSRTPPRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 534
Query: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
R EKER+ ++R R+R+R T + R+ DR+G+ + ++ ++++ KE D ++
Sbjct: 535 R--EKERDHISER-RERERST-SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 253 EERKKERKKERKK 265
+ K + E K
Sbjct: 591 VDDKDAPRTEENK 603
Score = 67.4 bits (163), Expect = 1e-11
Identities = 39/141 (27%), Positives = 73/141 (51%), Gaps = 5/141 (3%)
Query: 151 KERERQTEKDRDGQR--ETETERERDREREKQKERETERDRDRQRDTEKERERQT-DRER 207
KE E ++ R+ Q E E + E++ R R + R + K R+ + +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 208 DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD-RKEERKKERKKERKKE 266
R R R R+ DR + ++R + R+R + + R RD RK+ R+K ++KER KE
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 267 R-KEKKKEEKRREDKKRKWGE 286
+ +EK++E ++ +K+++ G+
Sbjct: 393 KDREKEREREKEREKEKERGK 413
Score = 67.4 bits (163), Expect = 1e-11
Identities = 48/206 (23%), Positives = 94/206 (45%), Gaps = 25/206 (12%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110
+ R +E R + H+ ++++E+D+ EKER++DR ++ + +RK+ + +
Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEKEKEQDK-----EKEREKDRSKEIDEKRKKDKKS 477
Query: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170
R R R + RER R R R R K +R++ + + + +
Sbjct: 478 RTPPRSYNAS-----RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Query: 171 RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETD 230
++R++ER+ ER R+R+R T R++ +RD + K + ++E +E D
Sbjct: 533 KKREKERDHISER-----RERERSTSM---RKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Query: 231 RRRERQRDRDRGKERDRERDRKEERK 256
++ D D++ R EE K
Sbjct: 585 SSVSKEVD-------DKDAPRTEENK 603
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 9/153 (5%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
KD R + R R+R R+R R R + + + + ++ R R + K
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-K 531
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE--- 186
K RE+ERD ER R+R+R R++ DRDG+ + E +E+E KE ++
Sbjct: 532 DKKREKERDHISER-RERERSTSM-RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589
Query: 187 --RDRDRQRDTEKERERQTDRERDRQR-KTQTE 216
D+D R E + + + + + + T+TE
Sbjct: 590 EVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 622
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 149 bits (376), Expect = 3e-36
Identities = 84/264 (31%), Positives = 147/264 (55%), Gaps = 30/264 (11%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDRVREKT-----EKERDRDRKRDRERR 103
S+ R S+ R H+ + R R++DR R K+ K R+R + R R
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257
Query: 104 RKEKETNRNRDREKQTEIERDRE--REKQKGRERERDRGRERERDRDREKERERQTEKDR 161
R +++ R + +EK+ E+DRE RE++K RE+E++RG+ ++RD++REK+RE+ EKDR
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 317
Query: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERE------------------RQT 203
+ +RE E E++RD+E+EK++++E ER++DR ++ +++R+ R +
Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Query: 204 DRERDRQRKTQTERQRETDREGERETDR----RRERQRDRDRGKERDRERDRKEERKKER 259
RER R+R + R T + +R++ R R ++D+ R KERD +R+E +
Sbjct: 378 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 437
Query: 260 KKERKKERKEKKKEEKRREDKKRK 283
++ +R K+K EK K K
Sbjct: 438 MRKSSNDRDGKEKLEKNSTSLKEK 461
Score = 149 bits (376), Expect = 3e-36
Identities = 81/259 (31%), Positives = 143/259 (55%), Gaps = 20/259 (7%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
S+ R S RS + + R + R+R R+ + RD+++D + KEKE
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIKEKER 273
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
+ +DREK+ E E++RE+EK++G+ ++RD+ RE++R++D+EK+RER+ EK+ + R+ E
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 170 ERERDREREKQKERETERDRDRQRDTEKE----------RERQTDRERDRQRKTQTERQR 219
E+E+D+E+E++K+R E D R++D + R R + RER R+R + R
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393
Query: 220 ETDREGERETDR----RRERQRDRDRGKERD-----RERDRKEERKKERKKERKKERKEK 270
T + +R++ R R ++D+ R KERD RER+R +K KE+ EK
Sbjct: 394 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453
Query: 271 KKEEKRREDKKRKWGEGIS 289
+ ++ ++ +S
Sbjct: 454 NSTSLKEKEHNKEPDSSVS 472
Score = 140 bits (353), Expect = 1e-33
Identities = 64/214 (29%), Positives = 125/214 (58%), Gaps = 2/214 (0%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTE-KERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
+ A + G +R+ R R T K R + R +R + K +R+ +R + + +R
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 232
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
R + K R + R+R + R R R+K ++ + EK ++ +R E +RE++REREK++E+
Sbjct: 233 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR-EKIKEKERVKEKDREKEREREKEREK 291
Query: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243
E ER +++ RD E+E++R+ D+E+DR+R+ + E +++ D+E E+E D+ +ER++DR +
Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351
Query: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
+ R++D+K ++ R ++ +RR
Sbjct: 352 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Score = 140 bits (352), Expect = 2e-33
Identities = 79/247 (31%), Positives = 130/247 (52%), Gaps = 36/247 (14%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
G++++ G R R + R ++ R R + + R R NR+R R+K +
Sbjct: 182 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH---NRSRSRQKDRRRSKSP 238
Query: 126 EREKQKGRERERDRGRERERD-----RDREKERERQTEKDRDGQRETETERERDREREKQ 180
+++ K RER + R R RD R++ KE+ER EKDR+ +RE E ERE+++ER K
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE------ 234
K+R+ ER++DR++D EK+RER+ ++E ++ R E+++E D+E ERE DR +E
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDR--DKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 235 --------------RQRDRDRGKERDRERDRKEERKK------ERKKERKKERKEKKKEE 274
+R R +ER R R R R +RK R + + K++
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Query: 275 KRREDKK 281
K+RE ++
Sbjct: 417 KKREKER 423
Score = 133 bits (335), Expect = 2e-31
Identities = 72/242 (29%), Positives = 129/242 (53%), Gaps = 20/242 (8%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRER-----RRKEKETNR 111
+ + R G ++H + + R + K R R R R R R K R
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 112 NRDREKQTEIERDREREKQKG-RERERDRGRERERDRDREKER--ERQTEKDRDGQRETE 168
++ RE++ R R+K+K RE+ +++ R +E+DR++E+ER ER+ EK+R ++ +
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Query: 169 TERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ--RKTQTERQRETDRE-- 224
ERE+DRE++K+K+RE ER+++ ++D +KE+E++ D+E++R+ R + + +R+ D++
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
Query: 225 --------GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
R RER+R R R R + +RK R + K+ KK EK
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Query: 277 RE 278
R+
Sbjct: 423 RD 424
Score = 132 bits (332), Expect = 4e-31
Identities = 65/199 (32%), Positives = 125/199 (62%), Gaps = 13/199 (6%)
Query: 89 EKERDRDRKRDRER---RRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER 145
E + +RK R R R K + ++++ R K+++ + R R + R R++DR R +
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQ-SKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 146 DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR 205
+ R K RER+ + R R+ +R+ RE+ K+KER E+DR EKERER+ +R
Sbjct: 239 HKKRSKSRERRKSRSRSHSRD---KRKDTREKIKEKERVKEKDR------EKEREREKER 289
Query: 206 ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKK 265
E++++R +R +E +++ E++ ++ RER+R+++ K+RD+E++++++++KER+K+R K
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Query: 266 ERKEKKKEEKRREDKKRKW 284
E EK+K++K+ R +
Sbjct: 350 EIDEKRKKDKKSRTPPRSY 368
Score = 121 bits (304), Expect = 6e-28
Identities = 68/222 (30%), Positives = 123/222 (55%), Gaps = 14/222 (6%)
Query: 70 KDADGDDRQRERDRVREKT-EKERDRDRKRDRERRR-------KEKETNRNRDREKQTEI 121
K D ++ +E++RV+EK EKER+R+++R++E+ R KE+E +R +D+EK E
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319
Query: 122 ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
ER++E EK + +E+E+++ +E+ER++DR KE + + +KD+ + + R R +
Sbjct: 320 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 379
Query: 182 ERETERDRDRQRD--TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
ER R R R T K +R++ R + + + +++RE +R+ RRER+R
Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD---HISERRERERST 436
Query: 240 D-RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
R DR+ K E+ KE++ ++ K +DK
Sbjct: 437 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478
Score = 118 bits (296), Expect = 5e-27
Identities = 60/203 (29%), Positives = 121/203 (59%), Gaps = 12/203 (5%)
Query: 90 KERDRDRKRDRERRRK-----EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
KE + KR RE + E E+ ++ +R+ R + + + R R R +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 215
Query: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE---KERER 201
+ R R R R +KDR +R ++R + RE++K R RD+++DT KE+ER
Sbjct: 216 KHRSRSHNRSRSRQKDR--RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKK 261
+++R+++R+ + ER++E +R ++ D+ RE+ R++D+ K+R+RER+++ E+ ++++K
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 262 ERKKER-KEKKKEEKRREDKKRK 283
E+++++ KE++K+ + D+KRK
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRK 356
Score = 94.7 bits (234), Expect = 8e-20
Identities = 58/193 (30%), Positives = 106/193 (54%), Gaps = 10/193 (5%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRR---KEKETNRNRDREKQTEIERDREREKQKG 132
D++RE+DR ++K EK+R+R+R+++ E+ R KEKE ++ ++REK E D +R+K K
Sbjct: 302 DKEREKDREKDK-EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK- 359
Query: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
+ R R R R R RER+ + R R T + R+ + + +D++
Sbjct: 360 KSRTPPRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 418
Query: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
R EKER+ ++R R+R+R T + R+ DR+G+ + ++ ++++ KE D ++
Sbjct: 419 R--EKERDHISER-RERERST-SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 253 EERKKERKKERKK 265
+ K + E K
Sbjct: 475 VDDKDAPRTEENK 487
Score = 67.4 bits (163), Expect = 1e-11
Identities = 39/141 (27%), Positives = 73/141 (51%), Gaps = 5/141 (3%)
Query: 151 KERERQTEKDRDGQR--ETETERERDREREKQKERETERDRDRQRDTEKERERQT-DRER 207
KE E ++ R+ Q E E + E++ R R + R + K R+ + +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 208 DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD-RKEERKKERKKERKKE 266
R R R R+ DR + ++R + R+R + + R RD RK+ R+K ++KER KE
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 267 R-KEKKKEEKRREDKKRKWGE 286
+ +EK++E ++ +K+++ G+
Sbjct: 277 KDREKEREREKEREKEKERGK 297
Score = 67.4 bits (163), Expect = 1e-11
Identities = 48/206 (23%), Positives = 94/206 (45%), Gaps = 25/206 (12%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110
+ R +E R + H+ ++++E+D+ EKER++DR ++ + +RK+ + +
Sbjct: 307 KDREKDKEKDREREREKEHEKDRDKEKEKEQDK-----EKEREKDRSKEIDEKRKKDKKS 361
Query: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170
R R R + RER R R R R K +R++ + + + +
Sbjct: 362 RTPPRSYNAS-----RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Query: 171 RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETD 230
++R++ER+ ER R+R+R T R++ +RD + K + ++E +E D
Sbjct: 417 KKREKERDHISER-----RERERSTSM---RKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Query: 231 RRRERQRDRDRGKERDRERDRKEERK 256
++ D D++ R EE K
Sbjct: 469 SSVSKEVD-------DKDAPRTEENK 487
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 9/153 (5%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
KD R + R R+R R+R R R + + + + ++ R R + K
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-K 415
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE--- 186
K RE+ERD ER R+R+R R++ DRDG+ + E +E+E KE ++
Sbjct: 416 DKKREKERDHISER-RERERSTSM-RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473
Query: 187 --RDRDRQRDTEKERERQTDRERDRQR-KTQTE 216
D+D R E + + + + + + T+TE
Sbjct: 474 EVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 506
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 147 bits (371), Expect = 1e-35
Identities = 80/214 (37%), Positives = 146/214 (68%), Gaps = 15/214 (7%)
Query: 77 RQRERD-RVREKTEKERDRDRK---RDRERRRKEKETNRNRDR---EKQTEIERDREREK 129
R+RER+ R++ +KER+ +RK R+RE+R++E+E R R+R EK+ E +++ K
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 130 QKGRERERDRGRERERDRDRE-KERERQTEKDRDGQRETETERERDREREKQKERETERD 188
++ RE+E G E+E+ + +E KER R +++ ++ +R+ E +RE +ERE++KE ER+
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE---ERE 155
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
++R+R K+RER+ E++ +RK + ER+ RE R + R+++R+R +ER +E
Sbjct: 156 KERERKERKKRERKQVGEKEEERK-EKERKERKKRERNR---KERKKERERKERRERKKE 211
Query: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
R +KEERKKER+K+R+ +EK++ ++ R+++K+
Sbjct: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 134 bits (336), Expect = 1e-31
Identities = 70/188 (37%), Positives = 130/188 (69%), Gaps = 8/188 (4%)
Query: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD 160
E R +E+E ++ +K+ E ER +ER +++ R+RER++ R+RER + +EK+ ER+ E+
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK-KEKKGERKKEER 95
Query: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
+R E E + E+EK+K++E +++R R KERER+ +R+R+ +RK + ++ E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKE-KKERGRTSKEGKERERKEERKRE-ERKERERKKEE 153
Query: 221 TDREGERETDRRRER----QRDRDRGKERDRERDRKEERKKERKKER-KKERKEKKKEEK 275
++E ER+ ++RER +++ +R ++ +ER ++E +KERKKER +KER+E+KKE K
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 276 RREDKKRK 283
++E++K++
Sbjct: 214 KKEERKKE 221
Score = 79.0 bits (193), Expect = 5e-15
Identities = 38/121 (31%), Positives = 80/121 (66%), Gaps = 6/121 (4%)
Query: 64 GLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
G + K+ + ++ER+R +E+ EKER+R ++ RER++ ++ +++E++ +R
Sbjct: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
+R R+++K +ERER RER+++R +++ER+++ +KDR RE++R + ++KER
Sbjct: 190 ERNRKERK-KERERKERRERKKERKKKEERKKERQKDRQ-----TNWREKERGKRERKER 243
Query: 184 E 184
+
Sbjct: 244 K 244
Score = 68.2 bits (165), Expect = 8e-12
Identities = 33/101 (32%), Positives = 67/101 (66%), Gaps = 9/101 (8%)
Query: 187 RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
R+R+R+ +T KE +++ + ER ++R+ + +R+RE RE +R+RER + +G+ +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKRE------REKERKRERGKKEKKGERKK 92
Query: 247 RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
ER+RK K+ R+KE K+ +++K+++K ++++ R EG
Sbjct: 93 EERERK---KRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
Score = 48.9 bits (115), Expect = 5e-06
Identities = 23/76 (30%), Positives = 50/76 (65%), Gaps = 4/76 (5%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRER---RRKEKETNRNRDREKQTEI 121
+G+ ++ +R+ + R R + E++++R+RK RER R+K++E + R +++QT
Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN- 229
Query: 122 ERDREREKQKGRERER 137
R++ER K++ +ER++
Sbjct: 230 WREKERGKRERKERKK 245
Score = 31.6 bits (70), Expect = 0.85
Identities = 14/37 (37%), Positives = 27/37 (72%), Gaps = 4/37 (10%)
Query: 251 RKEERKKERK----KERKKERKEKKKEEKRREDKKRK 283
+ E R++ER+ KE KKER+ ++K+E+R +K+++
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKR 71
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 141 bits (355), Expect = 8e-34
Identities = 84/196 (42%), Positives = 141/196 (71%), Gaps = 20/196 (10%)
Query: 94 RDRKRDRERRRKEKETNRNRDREKQTEIERDRER-EKQKGRERERDRGRERERDR-DREK 151
R+ +R +ERR +EK R R+REK ER RER +K+K + ++R+RG+ERER R +REK
Sbjct: 32 RESERKKERREREK---RKREREK----ERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 152 ERERQTEKDRDGQRETETERERD----REREKQKERETERDRDRQRDTEKERERQTDRER 207
+R+ + EK+R +++ + +RER RER+K+KER+ ER+R+ ++ E++R+++ ++R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKR 143
Query: 208 DRQRKTQTER-QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
++RK + ER +RE R+ ++ +R ++R+R+R KER +ER+RKE R ERKKERKKE
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKERR--ERKKERKKE 198
Query: 267 RKEKKKEEKRREDKKR 282
R++KK+ +K R+ ++
Sbjct: 199 RRKKKERKKDRKTDRQ 214
Score = 140 bits (354), Expect = 1e-33
Identities = 78/195 (40%), Positives = 133/195 (68%), Gaps = 15/195 (7%)
Query: 78 QRERDRVREKTEKE---RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
QRE +R +E+ E+E R+R+++R RER +KEK+ + R+R K ER+R+R +E
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK----ERERKR-----KE 81
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQR 193
RE+ R RE++R + K+ +++ E+ + G+RE + ++ER +RERE ++ RE +R + R++
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 194 DTEKERERQTDR-ERDRQRKTQTERQRETDREGER-ETDRRRERQRDRDRGKERDRERDR 251
KER+R+ +R +R+R+RK + + +RE RE R E + RER+ R+R KER +ER +
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 252 KEERKKERKKERKKE 266
K+ERKK+RK +R+ +
Sbjct: 202 KKERKKDRKTDRQTD 216
Score = 130 bits (327), Expect = 1e-30
Identities = 69/170 (40%), Positives = 127/170 (74%), Gaps = 10/170 (5%)
Query: 115 REKQTEIERDREREKQKGRERERDRGRER-ERDRDREKERERQTEKDRDGQRETETERER 173
RE + + ER REREK+K RERE++R RER ++++ + K+RER E++R ++E E +R+
Sbjct: 32 RESERKKER-REREKRK-REREKERKRERGKKEKKKRKKRERGKERERK-RKEREKQRKE 88
Query: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR 233
RE+E++K ++ ++ R+R++ +ER+++ +R ++R+ + +++RE R+ R+ RR+
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKRRKKKRRK 145
Query: 234 ERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
ER+R+++RGK RER RK+ +K+ER+K+R++ RKE+KKE +R+E ++RK
Sbjct: 146 ERKREKERGK---RERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Score = 116 bits (290), Expect = 3e-26
Identities = 67/163 (41%), Positives = 114/163 (69%), Gaps = 14/163 (8%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRER-RRKEKETNRNRDREKQTEIERDREREKQKGRER 135
++RER + RE+ KER++ RK RE+ RRK K+ + R+R+++ ER +++E+ K RER
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERER 125
Query: 136 ERDRGRERERDRDREKER--ERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E + RER+R + R+K+R ER+ EK+R +RER R++ K++ERE +R+R+R +
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERG-------KRERKRKKRKKEEREKKRERNR-K 177
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
+ +KERER+ RER ++RK ER+++ +R+ +R+TDR+ + Q
Sbjct: 178 ERKKERERKERRERKKERK--KERRKKKERKKDRKTDRQTDSQ 218
Score = 100 bits (248), Expect = 2e-21
Identities = 56/131 (42%), Positives = 94/131 (71%), Gaps = 13/131 (9%)
Query: 164 QRETETERERDREREKQK-ERETERDRDR---------QRDTEKERERQTDRERDRQRKT 213
QRE+E ++ER REREK+K ERE ER R+R +R+ KERER+ +ER++QRK
Sbjct: 31 QRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKE 88
Query: 214 QTERQRETDREGERETDRRRERQRDRDRGKER-DRERDRKEERKKERKKERKKERKEKKK 272
+ E++R ++ +++ +R++ +R+R + KER +RER+ K+ R+++RKK RKK+R++++K
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 273 EEKRREDKKRK 283
EK R ++RK
Sbjct: 149 REKERGKRERK 159
Score = 93.2 bits (230), Expect = 2e-19
Identities = 47/133 (35%), Positives = 96/133 (72%), Gaps = 5/133 (3%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQ--KGRE 134
R++ER R R+K +K+R+R ++ RER++K++ R R+ +++ E +R + R+K+ K R+
Sbjct: 90 REKER-RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 135 RERDRG-RERERDRDREKERERQTEKDR-DGQRETETERERDREREKQKERETERDRDRQ 192
RE++RG RER+R + +++ERE++ E++R + ++E E + R+R++E++KER +++R +
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 193 RDTEKERERQTDR 205
R T+++ + Q R
Sbjct: 209 RKTDRQTDSQVFR 221
Score = 77.0 bits (188), Expect = 2e-14
Identities = 38/110 (34%), Positives = 74/110 (67%), Gaps = 2/110 (1%)
Query: 64 GLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
G + K + +R+RE + RE+ K+R R +KR +ER+R+++ R R R+K+ + ER
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKR-RKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 124 DREREK-QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
+++RE+ +K R++ER+R RER ++R+KER ++ E+ +D + + +T+ +
Sbjct: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 42.4 bits (98), Expect = 5e-04
Identities = 21/46 (45%), Positives = 32/46 (69%), Gaps = 3/46 (6%)
Query: 241 RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
R ER +ER +E+RK+ER+KERK+ER K+EK++ K+ + E
Sbjct: 32 RESERKKERREREKRKREREKERKRERG---KKEKKKRKKRERGKE 74
Score = 40.8 bits (94), Expect = 0.001
Identities = 15/43 (34%), Positives = 34/43 (79%)
Query: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+R+ ER ++ +++RK+ER+KERK ++ ++++++ KKR+ G+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK 73
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 129 bits (324), Expect = 3e-30
Identities = 79/263 (30%), Positives = 141/263 (53%), Gaps = 31/263 (11%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGD---DRQRERDRVREKTE---KERDRDRKRDRE-RR 103
R L + SPR H++ G DR+ ER++ R++ E KER+++R+R R R
Sbjct: 264 RRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDR 323
Query: 104 RKEKETNRNRDREKQTEIERDRE---REKQKGRERERDRGRERERDRDREKERERQTEKD 160
E+ +R+R+R + RDR+ R++ + RE+E +RGR R+RD D+E+ ER+ E++
Sbjct: 324 GLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERE 383
Query: 161 RDGQRETETERERDREREKQKE-RETERDRDRQRDTEKERERQTDRERDRQRKTQT---- 215
R +R E + E +K KE ++ R RD +RD++KE++ R R+R+ ++++
Sbjct: 384 RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRN 443
Query: 216 --ERQRETDRE---------GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERK 264
+R R +E E+ R R + R E+ ++R+ ++K RK+ R
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRS 503
Query: 265 KERKEKK-----KEEKRREDKKR 282
KER K+ K++ + D++R
Sbjct: 504 KERSHKRDHSDSKDQSDKHDRRR 526
Score = 125 bits (314), Expect = 4e-29
Identities = 78/231 (33%), Positives = 119/231 (51%), Gaps = 28/231 (12%)
Query: 72 ADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
A+ DR ER R R R R R +E + + +++ E E++R+R +++
Sbjct: 248 AEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLERE 307
Query: 132 GRERERD--------RGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
+ERE++ RG ER R R RE+ R R +DR G R R+RDREREK+ ER
Sbjct: 308 AKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDR-----RDRDREREKENER 362
Query: 184 ETERDR--DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
RDR D++R E+E+ER+ RER ++++++ E + + +E + D RR R RD
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE---DKDDRRHRDDKRDS 419
Query: 242 GKERDRERDRKEERKK----------ERKKERKKERKEKKKEEKRREDKKR 282
KE+ R R ERK +R + R KE+ K K E + + KR
Sbjct: 420 KKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470
Score = 117 bits (292), Expect = 2e-26
Identities = 72/221 (32%), Positives = 121/221 (54%), Gaps = 16/221 (7%)
Query: 74 GDDRQRERDRVREKTEKERDRDRK---RDRERRR-KEKETNRNRDREKQTEIERDREREK 129
G +R+R R R R ++ + R RDRK RDR+R R KE E R RDR+ E +RE+E+
Sbjct: 324 GLERRRSRSRERHRS-RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKER 382
Query: 130 QKGRER---ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186
++ RER +R RG E+ +K+ R + RD ++E + R R RER K + R
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER-KHRSRSRS 441
Query: 187 RD---RDRQRDTEKERERQTDRERDRQRKTQTERQRETD---REGERETDRRRERQRDRD 240
R+ R R R EK + + + + +++++ Q TD + +RE +E+ R R
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRS 501
Query: 241 RGKERDRERDRKEERKKERKKERKKERK-EKKKEEKRREDK 280
R KER +RD + + + K +R++ + E++ +EK+ ++K
Sbjct: 502 RSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNK 542
Score = 116 bits (290), Expect = 3e-26
Identities = 73/225 (32%), Positives = 119/225 (52%), Gaps = 13/225 (5%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET---NRNRDREKQTEIERDRE 126
K+ D + R R ++ E + DR +R R R + + R+ R + R+
Sbjct: 227 KNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGH 286
Query: 127 REKQKGRERERDRGRER-ERD-RDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
RE ER++ R+R ER+ ++REKER R DR +R RER R R + ++R+
Sbjct: 287 GSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRK 346
Query: 185 TE-RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR-----RERQRD 238
+ RDRDR+R+ E ER R+ DR+ D++R + E++RE RE +E R ++ + D
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED 406
Query: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
+D + RD +RD K+E+K R R +ERK + + R K+ +
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSR--SRSRERKHRSRSRSRNAGKRSR 449
Score = 113 bits (282), Expect = 2e-25
Identities = 67/207 (32%), Positives = 107/207 (51%), Gaps = 18/207 (8%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
Q+ D+ + ++ +D K E + E R+R + R R + + RE
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK 197
+R+ +REKER+R +RE + ERE++R R + +R ER R R R+ +
Sbjct: 286 HGSSSFDRELEREKERQRL-------EREAK-EREKERRRSRSIDRGLERRRSRSRERHR 337
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
R R DR+ DR R R+ +RE E E RRR+R D++RG ER++ER+R ER K
Sbjct: 338 SRSRSRDRKGDR-------RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390
Query: 258 ERKKE---RKKERKEKKKEEKRREDKK 281
E++ +K+ KE K + + R+DK+
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKR 417
Score = 85.9 bits (211), Expect = 4e-17
Identities = 49/165 (29%), Positives = 86/165 (52%), Gaps = 8/165 (4%)
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
K + R+ ++D G+E + DR ER R R R R R ++ + D
Sbjct: 234 KTRPRKIKKD-GKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFD 292
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR-GKERDR 247
R+ +R+ E++R + +ER+++R+ R +R R +R R R R RDR G RDR
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 248 ERDRKEERKKERK------KERKKERKEKKKEEKRREDKKRKWGE 286
+R+R++E ++ R+ KER ER+++++ + R ++R GE
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGE 397
Score = 77.4 bits (189), Expect = 1e-14
Identities = 51/204 (25%), Positives = 99/204 (48%), Gaps = 28/204 (13%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKER------------DRDRKR 98
R R +E+ R + + G++R++ER+R RE+++++R D+D +R
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRR 411
Query: 99 DRERRR---KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERER 155
R+ +R KEK+ +R+R RE+ K + R R R+ G+ R R R +EK +
Sbjct: 412 HRDDKRDSKKEKKHSRSRSRER-----------KHRSRSRSRNAGK-RSRSRSKEKSSKH 459
Query: 156 QTE-KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
+ E K++ +R + R EK K+RE +++ R + +ER R+ +
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519
Query: 215 TERQRETDREGERETDRRRERQRD 238
+ R + E+E+ ++ + +D
Sbjct: 520 DKHDRRRSQSIEQESQEKQHKNKD 543
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 122 bits (307), Expect = 3e-28
Identities = 65/220 (29%), Positives = 136/220 (61%), Gaps = 12/220 (5%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE---REKQKGR 133
R+++ + RE+ E+ R++ +R+++ R+E++ R ++ ++ ++ R++E RE+Q R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E+E +R RE++ R+++ RE+Q +++ +RE + RE+ RE+Q RE + R++Q
Sbjct: 367 EQEEER-REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDR-------EGERETDRRRERQRDRDRGKERD 246
E+E ER + +R+ + +R++E R E ER RR++Q RD+ +ER
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER- 484
Query: 247 RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
RER K E ++ R+++ ++E++ ++++E+RRE + ++ E
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Score = 121 bits (304), Expect = 6e-28
Identities = 75/248 (30%), Positives = 146/248 (58%), Gaps = 20/248 (8%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDR-KRDRERRRKEKETNR 111
+L +E R L + + +RQ R RE+ E+E+ + R +R+++ RRK++E R
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELR---RERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 112 NRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR----DGQRET 167
+ E++ + ER ++E+++ ++ R++ RE+ RE+E ER+ ++ R + +RE
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 168 ETERERDREREKQKERETERDRDRQ--RDTEKERERQTDRERDRQRKTQTERQRETDREG 225
+ RE+ RE+Q RE + R++Q R+ + RE+Q RE+ +R+ Q R++E +R
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 226 ERETDRRRERQRDRDRGKERD-------RERDRKEERKKERKKERKKERKE---KKKEEK 275
++ RRE++ R++ + RD ER +E RK++ K+++++ER+E K +EE+
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 276 RREDKKRK 283
RRE ++R+
Sbjct: 496 RREQQERR 503
Score = 120 bits (300), Expect = 2e-27
Identities = 73/246 (29%), Positives = 143/246 (58%), Gaps = 15/246 (6%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKE-- 108
R R QE R L + + ++ +R +RDR R E R R ++RE RR E+E
Sbjct: 136 RRRQKRQEQERE--LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193
Query: 109 -TNRNRDREKQTEIERDRERE----KQKGRERERDRGRERER---DRDREKE-RERQT-- 157
+ + + E+ + E+ R RE ++KGRE ++ + RER+ + EKE R+R+T
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 158 EKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217
K+ + +E E +R+R+ + E+++ R+ ER R+ E+E+++Q R + R+ Q E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
+RE E + +RR +++ R++ R++E R+++ ++E+++ER++++ +++EE+RR
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 278 EDKKRK 283
E + R+
Sbjct: 374 EQQLRR 379
Score = 119 bits (298), Expect = 3e-27
Identities = 62/236 (26%), Positives = 140/236 (59%), Gaps = 10/236 (4%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
+E R + ++ +++Q++R R ++ ++++ +R+ +E RR+++E ++
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 117 KQTEIERDRE--REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD 174
++ ++ R++E RE+Q RE+E +R ++ R E+ RE+Q +++ +RE + RE+
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 175 REREKQKERETERDRDRQ--RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR 232
RE+Q RE + R++Q R+ + RE+Q RE++ +R Q Q ++ +RE + R
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 233 RERQRDRDRGKERDRERDRKEERKKERKKERKK-----ERKEKKKEEKRREDKKRK 283
R+ + R+ ER + RK++ K+++++ER++ E +E++++++RRE + R+
Sbjct: 455 RDWLK-REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Score = 117 bits (294), Expect = 9e-27
Identities = 68/239 (28%), Positives = 143/239 (59%), Gaps = 10/239 (4%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
R+ +E + W + + + Q E + + + ++E ++ RK +R+ R+E++
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 113 RDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
+ + + E + R++E+++ RE++ +R ++ER +E+ RE+Q ++++ +RE + RE
Sbjct: 296 QQQRLRREQQLRRKQEEER-REQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 173 RDRE-REKQKERETERDRDRQ---RDTEKERERQTDRERDRQRKTQTERQRETDREGE-- 226
++ E RE+Q RE E +R Q R+ + RE+Q RE+ +R+ Q R+++ RE +
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 227 RETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKE--KKKEEKRREDKKRK 283
RE RRE+Q R++ +ER E+ ++ER+++R K ++ER++ K++EE R +++R+
Sbjct: 415 REQQLRREQQLRREQEEER-HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Score = 117 bits (293), Expect = 1e-26
Identities = 62/238 (26%), Positives = 143/238 (60%), Gaps = 12/238 (5%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRER--DRVREKTEKERDRDRKRDRERRRKEKETNRNRD 114
QE R + + + ++Q ER ++R + E+ R++ +R++E R+E++ R ++
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 115 REK-QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
E+ + ++ R+++ +++ RE+ RE++ R+++ RE+Q +++ +RE + RE+
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
Query: 174 DREREKQKERETERDRDRQRDTEK-----ERERQTDRERDRQRKTQTERQRETDREG--- 225
+ ER +QK + R++ +R+ E+ +RE +T+R +RK Q +R +E +R
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
+ E + RRE+Q R++ R++E +R+E+R K +++E + +++ + +++ RRE ++R+
Sbjct: 490 KLEEEERREQQERREQQLRREQE-ERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Score = 115 bits (289), Expect = 3e-26
Identities = 69/237 (29%), Positives = 139/237 (58%), Gaps = 28/237 (11%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRR-----------KEKETNRNRD--REKQTEI 121
++ +RE+ RE+ E+ R++ +R+++ RR +E++ R + RE+Q
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 122 ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG-QRETETERERDREREKQ 180
E+ RE+Q RE+E +R ++ RE+ +R+ E+ RD +RE ETER R++Q
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 181 KERETERDR---------DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER---E 228
+R+ E +R + +R+ ++ RE+Q RE++ +R+ + +RQ E +R +R E
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 229 TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEK--KKEEKRREDKKRK 283
RRE++ R++ +R+ E+ ++ER+++R K ++ER+++ K+EE+RR+ + ++
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Score = 112 bits (279), Expect = 5e-25
Identities = 63/220 (28%), Positives = 138/220 (62%), Gaps = 13/220 (5%)
Query: 77 RQRERDRVREKTEKERDRDRK---RDRERRRKEKETNRNRDREKQTE----IERDREREK 129
R+ +DRV ++ E++ R R+ R E + +E+E R R+ +++ E +ER R +
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
++ E+++ R R ++ R +++E R+ +++R Q+E ++E RE++ ++E+E R++
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 190 DRQRDTEKER-ERQTDRERDRQRKTQT---ERQRETDREGERETDRRRERQRDRDRGKER 245
+R+ E+ER E+Q RE++ +R+ Q E+Q +++ RE RRE+Q R++ R
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409
Query: 246 DRERDRKEERKKER--KKERKKERKEKKKEEKRREDKKRK 283
+++ R+++ ++E+ ++E+++ER E+K E++RRE + ++
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 110 bits (274), Expect = 2e-24
Identities = 67/229 (29%), Positives = 137/229 (59%), Gaps = 22/229 (9%)
Query: 77 RQRERDRVREKTEKERDRDR-KRDRERRR----KEKETNRNRDREKQTEIERDREREK-- 129
R++E +R +K E+ER R KR++E RR +E+ET R+ ++ +++RD+E E+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 130 -----QKGRERERDRGRERERDRDREKERE----RQTEKDRDGQR---ETETERERDRER 177
++ RE+ RE++ R++E+ RE RQ E++R QR E + RE++ R
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237
E+ +RE E+ +++R ++ + Q +R ++ + RQ+ RE E ++R +R+
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 238 -DRDRGKERDRERDRKEERKKERKKE--RKKERKEKKKEEKRREDKKRK 283
+R +ER +R ++EE ++ER+++ + +E++E+++++ RRE ++R+
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Score = 110 bits (274), Expect = 2e-24
Identities = 62/236 (26%), Positives = 136/236 (57%), Gaps = 14/236 (5%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L Q + G++ ++ R + REK +E + ++ + + R+E+E R ++ E+Q + +
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
++E+++ ER++ R +ER+R +E E Q E+++ E ET R ++ ER+ +KE E
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
+++ ++ E E+ R+ +RER + + + +++ E ERE RR+E +R +E
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 245 RDRERDR--KEERKKERKKERKKERKE------------KKKEEKRREDKKRKWGE 286
+E ++ +EE +K R++E +++ +E ++++EKRR++++R++ E
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Score = 107 bits (266), Expect = 2e-23
Identities = 58/222 (26%), Positives = 129/222 (58%), Gaps = 12/222 (5%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
++R++ R + E+ +++D ++ + + R+E+E R ++RE+Q E + ++E+++
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
ER+ R +E +R KE E Q E+++ + E E R ++RER+ ++E E +++ ++
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE-----R 249
E+E+ R+ + ER + + + +++ E E E RR+E +R +E +E R
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 250 DRKEERKKERKKERKKE-------RKEKKKEEKRREDKKRKW 284
+ +E+R++ER+++ ++E RK++ ++E +R D K +W
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQW 1227
Score = 105 bits (262), Expect = 5e-23
Identities = 60/209 (28%), Positives = 127/209 (60%), Gaps = 6/209 (2%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
R+RE +R K +E+ + R+ ++R +E+E R RE E ++ +E++ R+RE
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 137 RDRGRERERDRDREK-ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
E+ R +R++ RERQ E+ + + E + R +E E+++++E R++ +R+
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 196 EKER-ERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
++ER E+Q RE++ +R+ Q R++E +R RE RRE++ +R R ++ RE+ + E
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEER---REQQLRREQEEER-REQQLRREQQLRRE 386
Query: 255 RKKERKKERKKERKEKKKEEKRREDKKRK 283
++ R+++ ++E++ +++++ RRE + R+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRR 415
Score = 105 bits (261), Expect = 6e-23
Identities = 56/237 (23%), Positives = 140/237 (59%), Gaps = 15/237 (6%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L + ++ ++R++ R + +E+ +E ++ ++ + + R+E+E R ++RE+Q ++
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
++++++ E ++ R +ER++ +E E Q E+++ + E E R ++ ER+ +K+ E
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
+++ ++ E+E+ R +RER + + + +++ E ERET RR+E +R + +E
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 245 RDRERDR--KEERKKERKKERKKERKE-------------KKKEEKRREDKKRKWGE 286
+E ++ +EE +K R++ER+++ +E +++E++RR++ +R++ E
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Score = 105 bits (261), Expect = 6e-23
Identities = 60/218 (27%), Positives = 134/218 (61%), Gaps = 15/218 (6%)
Query: 77 RQRERDRVREKTEK----ERDRDRKRDRERRRKEK-------ETNRNRDREKQTEIERDR 125
+Q E +RE+ EK ER+R ++D++ ++KE+ E R ++REK+ E +
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
++E+++ ER++ R +E +R K+ E Q E+++ + E E R ++RER+ ++E E
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
+++ ++ E+E R+ +E +RQ + + E Q+E ++ E ++RR ++R+R +E
Sbjct: 1057 QQEEEQLLGEERETRRR--QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 246 DRERDRKEERKKERKKERKK--ERKEKKKEEKRREDKK 281
+ +++ ++ ++ER+K R++ ER+ +++EE ++E+++
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Score = 104 bits (260), Expect = 8e-23
Identities = 61/213 (28%), Positives = 123/213 (57%), Gaps = 8/213 (3%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD---REKQTEIERDREREKQKGRE 134
+RE+ RE+ E+ ++ +++R +R ++E RD RE++TE R++Q R+
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ-- 192
+E +R RER + E+ RE+Q +++ +RE E RE+ +R++++ER +R R Q
Sbjct: 480 QEEER-RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
R ++ER Q + + +R Q R++ RE E D+ +R+ +R + + + + +R
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 253 EERKKERKKER--KKERKEKKKEEKRREDKKRK 283
E+R K + ER ++ER+E++ + + E+++R+
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Score = 103 bits (258), Expect = 1e-22
Identities = 68/240 (28%), Positives = 136/240 (56%), Gaps = 22/240 (9%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
QE R W L + + + +R++ R++ E+ R+R K + E RR+++E RE
Sbjct: 451 QEERRDW-LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER-----RE 504
Query: 117 KQTEIERDREREKQKGRERERDRGRERERD-----RDREKERERQTEKDRD-----GQRE 166
+Q E++ RE++ R+ E +R ++R R R++E+ RE+ +++ + +RE
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 167 TETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226
+RE++ R++ +RE ER + R + ++ER Q + + +R Q ER+ + + E
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 227 RETDRRR-----ERQRDRDRGKERDRERDRKEER-KKERKKERKKERKEKKKEEKRREDK 280
E +RR+ E Q +R + + R +++R+E+R K+E ++ER ++R +++ EE+RRE +
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Score = 103 bits (258), Expect = 1e-22
Identities = 62/222 (27%), Positives = 127/222 (57%), Gaps = 13/222 (5%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER---EKQK 131
D + R+R + E+ER ++R ++ R+E+E R + ++Q E ER ++R E+Q
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 132 GRERERDRGRERERDRDREKERERQTEK---DRDGQRETETERERDREREKQKERETERD 188
RE+E R + +R+ ++ E+ER+ ++ +++ +R+ +RE +R +++ K + ER
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRET------DREGERETDRRRERQRDRDRG 242
R + E ER Q +R R ++ + E +R ++E R+ RRE+Q R++
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658
Query: 243 KERDRERDRKEER-KKERKKERKKERKEKKKEEKRREDKKRK 283
+R+ E +R E+R K+E ++ER+++ ++++E+ RE K +
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700
Score = 103 bits (258), Expect = 1e-22
Identities = 61/215 (28%), Positives = 122/215 (56%), Gaps = 3/215 (1%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD-REREKQKGR 133
++R++ R + E+ +E + ++ + + R+E E R ++ E+Q E + ++ E+Q R
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E + R +ERER E+E +RQ K R + ++ + E EK+ + + R
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER-DRK 252
+ E+ R+ + + RDRQ + + +E +RE +RRR +QRDR +E ER ++K
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 253 EERKKERKKERKKE-RKEKKKEEKRREDKKRKWGE 286
E ++++RK + +K+ +E+++E++RR++ RK+ E
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Score = 103 bits (257), Expect = 2e-22
Identities = 53/213 (24%), Positives = 127/213 (59%), Gaps = 6/213 (2%)
Query: 75 DDRQRERDRV------REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRERE 128
++R+R R + +E+ KE+ ++ + E +R+E+E R +++E+Q E ++E
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
+++ ER++ R +ER+R K+++ Q ++++ E E R ++RE++ ++E E +++
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
++ E+E+ R+ + ER ++K + +++ E ERE R +ER+R +E +E
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
++ ++E ++ ++ ER+ +K+EE ++E+++
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092
Score = 103 bits (256), Expect = 2e-22
Identities = 60/215 (27%), Positives = 120/215 (55%), Gaps = 16/215 (7%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRR---KEKETNRNRDREKQTEIER----DRERE 128
+++R R++ + E+ RD+ KR+ ERR+ K ++ R R K+ E+ER +R +
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER-EKQKERETER 187
+ K E E +R ++ + ++E+ R++Q +++ +RE +RE + ER E++ +RE E
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Query: 188 DRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
+R Q E+E+E+ +R + R K Q + E E D R+ + R R +E R
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQL--------ESEADARQSKVYSRPRKQEGQR 730
Query: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
R +EE+++ R+ E + + +E+ +++ E+++R
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Score = 103 bits (256), Expect = 2e-22
Identities = 55/214 (25%), Positives = 131/214 (61%), Gaps = 9/214 (4%)
Query: 79 RERDRVREKTEK----ERDRDRKRDRERR-RKEKETNRNRDREKQTEIERDREREKQKGR 133
RE ++++++ E+ ER++ R+++RER+ RK+K+ + ++ E E+ R +E++K
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR----EREKQKERETERDR 189
E + +E E+ E+E+ R+ E +R +++ E ++E ++ EREK++ +E ER
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER 249
+ + ++E E+ ER+ +R+ + ERQ + E ++E ++ + ++ R +ER+R+
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 250 DRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
+EE ++E ++ ++ER++++++E R+ ++ +
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Score = 102 bits (255), Expect = 3e-22
Identities = 60/218 (27%), Positives = 129/218 (59%), Gaps = 10/218 (4%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
+++ RD ++ + E ER +R ++ +R ++E R R + + E R+++ +++ R
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 136 ERDRGRERERDRDREKER-ERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
E++ RE+ R E+ER +++ ++ +RE E RE+ +RE++K E ER R +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 195 TEKER-----ERQTDRERDRQRKTQTER--QRETDREGER-ETDRRRERQRDRDRGKERD 246
++ER +R+ +R + R ++ Q ER QR E ER E + RRE++ R+ +E
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 247 RERDRKEERKKERKKER-KKERKEKKKEEKRREDKKRK 283
R++ K E ++ER++++ ++E++E++++ +RE+++ +
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Score = 102 bits (253), Expect = 5e-22
Identities = 75/248 (30%), Positives = 141/248 (56%), Gaps = 21/248 (8%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKE-KET 109
R R +ES L Q + + R RDR E+ +R R +++++ER E +E
Sbjct: 100 RARCDGKES-----LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 110 NRNRDREKQTEIERDRE---REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRE 166
+ ++R +Q + +R E R++Q+ +ERE R E + + E E ++++ +RE
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 167 TETERERDREREKQKERETERDRDRQRDTEKE-RERQT--DRERDRQRKTQTERQRETDR 223
R + RE EKQ++R +DR Q + EKE R+R+T +E ++ ++ + +RQRE
Sbjct: 215 LLELRRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 224 EGE--RETDR---RRERQRDRDRGKERDRE---RDRKEERKKERKKERKKERKEKKKEEK 275
E E R+ +R RRERQ + + + RE R ++EE ++E+++ER+++++ ++++E+
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 276 RREDKKRK 283
RRE + R+
Sbjct: 334 RREQQLRR 341
Score = 101 bits (252), Expect = 7e-22
Identities = 64/255 (25%), Positives = 132/255 (51%), Gaps = 37/255 (14%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L Q + G++R+ R + E+ ++ + ++ + + R+E E R ++RE+Q E +
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
++E+++ ER++ R +E +R +E E Q E+++ + E E R ++ ER+ ++E E
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 185 TERD-----RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG-------------- 225
+++ R+ Q +ERERQ E + QR+ + +R R+ D+
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 226 ----------ERETDRRRERQRDRDRGKERD--------RERDRKEERKKERKKERKKER 267
E E R+ E + RDR ++D +ERDR++ER++ ++++R
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 268 KEKKKEEKRREDKKR 282
+E+ + E+++E K+R
Sbjct: 1296 EEQLEREEQKEAKRR 1310
Score = 101 bits (251), Expect = 9e-22
Identities = 72/258 (27%), Positives = 142/258 (55%), Gaps = 28/258 (10%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKE------ 106
R +E R L + ++ + + R ++R + + R++ +R+++ RR++
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
Query: 107 ---KETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD---REKERERQTEKD 160
+E R+++ + E E +R +K + RE+ RE+E RD RE+E ER ++
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 161 RDGQRETETERER--------DREREKQKERETERDRDRQRDTEKER-ERQTDRERDRQR 211
R Q + + E ER + ER +Q+ER ++ R Q + ++R +RQ + ER +QR
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 212 ---KTQTERQRETDREG--ERETDRRRERQRDRDRGK-ERDRERDRKEERKKERKKER-K 264
+ Q R++E RE +RE ++R E++R R K E++ RD+ +R++ER+++R K
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 265 KERKEKKKEEKRREDKKR 282
+E++E+ ++ +RE+ +R
Sbjct: 592 REQEERLEQRLKREEVER 609
Score = 100 bits (250), Expect = 1e-21
Identities = 61/230 (26%), Positives = 137/230 (59%), Gaps = 26/230 (11%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRK---EKETNRNRDREKQTEIERD---REREKQ 130
+QRE+ + E+ EKE+ R ++R+RE+ + E+E + R+R +Q + E D ++E++
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 131 KGRERERDRGRERERDRDREKER---------ERQTEKDRDGQRETETERERDREREKQK 181
+ +E+ RD+ + + +R++ R + Q K++ +E E E +R+ EREK++
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE-EREKRR 922
Query: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER--------ETDRRR 233
+E ER + ++E E+ ER+++R+ + ERQ D++ ++ E ++RR
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 234 ERQRDRDRGKERDRERDRKEERKKERKKERKK--ERKEKKKEEKRREDKK 281
++R++ +E + +++ ++ ++ER+K R++ ER+ +KK+E ++E+++
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
Score = 100 bits (250), Expect = 1e-21
Identities = 68/230 (29%), Positives = 133/230 (57%), Gaps = 23/230 (10%)
Query: 78 QRERDRV---REKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
++ERDR E+ + ++RDRK R++E R +E E + ++ +R R+ +++ +
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR---- 189
R ++RG++R +DRDR+ E Q ++R+ Q+ + ER+R E+QK R E++R
Sbjct: 1540 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 190 DRQRDTEKERERQTDRERDR----------QRKTQTERQRETDREGERETDRRRERQRDR 239
D Q+ +E ++Q +ERDR +R+ Q ++E DR+ E + R ++R++
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Query: 240 DRGKERDRERDRKEE--RKKERKKERKKERKEKKKEEK---RREDKKRKW 284
+RDR+ +E+ ++ E ++ R++ER K +EE+ RR++++RK+
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Score = 100 bits (248), Expect = 2e-21
Identities = 66/236 (27%), Positives = 126/236 (53%), Gaps = 15/236 (6%)
Query: 62 SWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERR----RKEKETNRNRDREK 117
+W K G R R +RE+ E++ + ++ RE+R +EKE R + RE+
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177
+ E++ E E+ + RER + +E E ++ER R E+ RD + + E ER R R
Sbjct: 828 EKELQFLEEEEQLQRRERAQQL-QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 178 EK--QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR--RR 233
K E+ R Q+ ++E E ER+++R+ + ERQ + + ++E ++ R
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 234 ERQRDRDRGKERDRERDRKEERKKER------KKERKKERKEKKKEEKRREDKKRK 283
ER++ R + +ER +D+K ++K+E+ +K R++ER++K +EE+ + ++ +
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Score = 99.8 bits (247), Expect = 3e-21
Identities = 72/247 (29%), Positives = 135/247 (54%), Gaps = 42/247 (17%)
Query: 77 RQRERDRVREKTEKER-DRDRK-RDRERRRKEKETNRNRDREKQTEIERDREREKQ---- 130
+Q E +RE+ EK R +R+R+ R+ E +++K R RD +++++++ E EK+
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 131 ------KGRERE----------RDRGRERE--------RDRDREKERERQTEKDRDGQRE 166
KGRE E RDR +++ ++RDRE+ER R ++DR E
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 167 TETERERDRE-----REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
+ ERE +E R+ Q+E++ R+ EK R ++TDR+ + + ER+ +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 222 DREGERETDRRRERQRDRDRGKE--RDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
R ER+ R E R +++G++ + +R R++ER+++ KE ++ R + ++E++ R+D
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ-EREQQLRQD 1411
Query: 280 KKRKWGE 286
+ RK+ E
Sbjct: 1412 RDRKFRE 1418
Score = 99.0 bits (245), Expect = 4e-21
Identities = 71/247 (28%), Positives = 131/247 (53%), Gaps = 31/247 (12%)
Query: 63 WGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIE 122
+ LGQA D + R R + ++ ++ D++R R R+ +E R R+K+ E E
Sbjct: 87 YALGQA-TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE 145
Query: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET----------ETERE 172
R+ +++ ++ER R+R+R RD E R+RQ ++R+ +R ETE
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQR-RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 173 RDRER---------------EKQKERETERDRDRQRDTEKE-RERQTDRERDRQRKTQTE 216
D E+ EKQ++R +DR Q + EKE R+R+T ++ ++ + E
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 217 RQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
QR+ + + E E R+ ERQ R +ER E +++ ++E++ RK+E + ++++E+R
Sbjct: 265 PQRQRELQEEEEQLRKLERQELR---RERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 277 REDKKRK 283
RE ++R+
Sbjct: 322 REQQERR 328
Score = 99.0 bits (245), Expect = 4e-21
Identities = 54/214 (25%), Positives = 119/214 (55%), Gaps = 7/214 (3%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
++R++ R + RE+ +E + ++ + + +E+ET R ++ E+Q E + ++E+++
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
E ++ R +ER+R +E E Q E+++ + E E R ++ ER+ ++E E +++ ++
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 195 TEKERERQTDRERD-------RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
E E+ R+ + ER +Q + Q R+ + R ERE R E + R + K+R R
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
+ D++ + K + + E++ ++ K K RE+++
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Score = 99.0 bits (245), Expect = 4e-21
Identities = 81/271 (29%), Positives = 149/271 (54%), Gaps = 43/271 (15%)
Query: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKER----DRDRK---RDRERRRKE 106
L ++ R GQ + D D + RE +++R++ E+++ +RDRK +++ RR+E
Sbjct: 1534 LQEEQQLRRQERGQQRRQ-DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 107 KETN--------RNRDREKQTEIERDR----------EREKQKGRERERDRGRERERDRD 148
+E R ++ ++Q ERDR ERE+Q+ +ERDR E +
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208
R +ERE+Q DRD R+ E + +E E+Q+ R ERDR + R+ E++ RQ +RER
Sbjct: 1653 RRQEREQQLRHDRD--RKFREEEQLLQEGEEQQLRRQERDR-KFREEEQQLRRQ-ERERK 1708
Query: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR----------ERDRKEERKKE 258
++ Q R++E +R+ E R+E ++++ R +ER R ER+ ++ R++E
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 259 RKKERKKE---RKEKKKEEKRREDKKRKWGE 286
R ++ ++E R+E+++++ R ++ RK+ E
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Score = 98.6 bits (244), Expect = 6e-21
Identities = 65/232 (28%), Positives = 124/232 (53%), Gaps = 22/232 (9%)
Query: 77 RQRERDRVREKTEKERDRD---RKRDRERRRKEKETNRNRDREKQTEIERD-REREKQKG 132
RQ + RE+ E +++ + R+ +RRR+E E + E Q E E+ RE ++++
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Query: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERE------------RDREREKQ 180
+ERER E E R + K+R R ++ D + + E E+E R+ E+ +Q
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE-RQRDR 239
E RDR Q+D + Q +R+R+++R+ +R R E + E + ++E ++RDR
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 240 DRGKERDRERDRKEERKKERKKERKKERKEKKKEEK-----RREDKKRKWGE 286
+E+ R+ +EE+++ ++ +RK +E+ +E+ RR+++ RK+ E
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Score = 98.2 bits (243), Expect = 7e-21
Identities = 56/216 (25%), Positives = 125/216 (57%), Gaps = 8/216 (3%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
++ +RE+ RE+ + +R+ R +R++E+E + R R +Q ++ R++E +++ +
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ-QLRREQEERREQLLK 551
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQR 193
RE ++ E+ER R++ +RE++ +D+ +RE E ++R RE+E++ E+ +R+ +
Sbjct: 552 REEEKRLEQER-REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 194 DTEKERERQTDRERDRQRKTQT-----ERQRETDREGERETDRRRERQRDRDRGKERDRE 248
+ E+ RE++ RE + + Q E++ ++ RE RRE++ R+ +ER +
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
R ++E ++ R++E +E +E+ +E + K +W
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Score = 98.2 bits (243), Expect = 7e-21
Identities = 61/242 (25%), Positives = 126/242 (52%), Gaps = 31/242 (12%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN----RDREKQTEIERDREREKQ 130
+ +R R++ + E+ER + R R ++ R+E+E R R+ EK+ E ER +R K+
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190
+ ER RD+ +RE +R +++ + Q E+ + E ER ER +Q+ + E + +
Sbjct: 570 EQEER-RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERE-TDRRRERQRDRDRGKER--DR 247
R++ K E++ R++ +R+ Q R++ RE E E ++R +R+ + +R ++ +
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Query: 248 ERDRKEERKKER-----------------------KKERKKERKEKKKEEKRREDKKRKW 284
E+++ ER K R +K+ + R+++++E++RR + + +W
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW 748
Query: 285 GE 286
E
Sbjct: 749 QE 750
Score = 97.8 bits (242), Expect = 1e-20
Identities = 54/206 (26%), Positives = 128/206 (62%), Gaps = 16/206 (7%)
Query: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDR 139
+ +++R + E R + +++++R+E++ DR Q E E+++ R+RE
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQ-----DRVFQ-------EEEEKEWRKRETVL 253
Query: 140 GRERERDRDREKERERQTEKDRDGQRETE-TERERDREREKQKERETERDRD-RQRDTEK 197
+E E+ ++ E +R+R+ +++ + R+ E E R+R+ E+Q+++ R++ R++ E+
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
RE+Q +R ++R+ Q E +RE ++ RE + RRE+Q R++ +ER ++ R+E+ ++
Sbjct: 314 RREQQEERREQQERREQQEERRE--QQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 258 ERKKERKKERKEKKKEEKRREDKKRK 283
R+++ ++E++ +++++ RRE + R+
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRR 397
Score = 97.8 bits (242), Expect = 1e-20
Identities = 58/213 (27%), Positives = 125/213 (58%), Gaps = 9/213 (4%)
Query: 78 QRERDRVREKTE-KERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Q+ERDR +E+ ++RDR + + R+E++ + RDR+ Q E + RE ++K R +E
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 137 RDRGRERERD--RDREKERERQTEKDRDGQRETETERERDRE--REKQKERETERDRDRQ 192
DR E ++RE++ R+ E+DR + E +E+ R+ E+Q+ R ER+R
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFL 1393
Query: 193 RDTEK----ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
++ ++ ERE+Q ++RDR+ + + ++ +R+ + + ++ R+++R+R + +
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
+ R+E +K R++E+ + +E+++ ++ D+K
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Score = 97.4 bits (241), Expect = 1e-20
Identities = 68/243 (27%), Positives = 136/243 (55%), Gaps = 23/243 (9%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERD-RDRK---RDRERRR-KEKETNRNRDREKQTEI 121
Q K D+ QR + + + EKE RD K + RE + ++ E ++ RDR+ Q ++
Sbjct: 1208 QKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL 1267
Query: 122 ERDREREKQKGRERERDRGRERERDRDREKERERQTEKD---RDGQRETETERERDRERE 178
+ ++++ RE+ER R ++R+R E++ ER+ +K+ RD + + E + R+ E
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327
Query: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTE--RQRETDREGERETDRRRERQ 236
K++ +ET+R + +ERE Q R ++R RK + E R +E R+ E R R ++
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE 1387
Query: 237 RDR------------DRGKERDRERDRKEERKKERKKERKKERKEKKKEEK-RREDKKRK 283
R+R +R ++ ++RDRK ++++ ++++RK +++E++ RR++++RK
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Query: 284 WGE 286
+ E
Sbjct: 1448 FLE 1450
Score = 97.4 bits (241), Expect = 1e-20
Identities = 72/246 (29%), Positives = 135/246 (54%), Gaps = 36/246 (14%)
Query: 77 RQRERDRVREKTE-----------KERDRDRKRDRERR-RKEKETNRNRDREKQTEIERD 124
R++ERDR + E +E R R+++RER+ KE++ R ++RE+Q +RD
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 125 RE--REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
R+ E+Q+ +ERDR E + R +ERER+ ++ R+ + R+ E+ Q+
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 183 RETERDR-DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR-- 239
E + R +R R +E ++ +ERDR+ + Q R +E +R+ E + +QR R
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 240 ----------DRGKERDRERDRK--------EERKKERKKERKKERKEKKKEEK-RREDK 280
+RG++R ++RDRK +ER++++ ++++RK + +E+K RR+++
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 281 KRKWGE 286
+RK+ E
Sbjct: 1594 ERKFME 1599
Score = 97.1 bits (240), Expect = 2e-20
Identities = 68/227 (29%), Positives = 127/227 (55%), Gaps = 21/227 (9%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR---DREKQTEIERDREREKQKGRE 134
+ + +R +K K RDR + +++ R+E+E R R DR+ + E + +ERE+Q R
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
+ERDR E R +E+ R+ E+ R ++E E + ++ ++ + +ERE + +DR R
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 195 TEKERERQTDRERDRQRKTQTERQRETDREG---ERETDRRRERQR----------DRDR 241
+E ++ + +ERDR+ + + ++ R +RE E E R+ER R +R+
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 242 GKERDRERDRK--EERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+ +ERDRK EE ++ R++ER ++ +E +E R ++ +RK+ E
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFRE---QELRSQEPERKFLE 1519
Score = 95.9 bits (237), Expect = 4e-20
Identities = 70/245 (28%), Positives = 139/245 (56%), Gaps = 18/245 (7%)
Query: 49 FSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTE---KERDRDRKRDRERR-R 104
F L SQE R + ++ +QR+R ++E+ + +ER + R++DR+R+ R
Sbjct: 1503 FREQELRSQEPERKF----LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 105 KEKETNRNRDREKQTEIERDRE--REKQKGRERERDRGRERERDRDREKERERQTEKDRD 162
+E++ + R+ ++ + ERDR+ E+QK R +E++R + + R +E ++Q ++RD
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 163 GQRETETERERDREREKQKERETERDRD--RQRDTEKERERQTDRERDRQRKTQTERQRE 220
R+ + + +ERE+Q+ ERDR + + +ER+ DR RK + E Q
Sbjct: 1619 --RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ-- 1674
Query: 221 TDREGERETDRRRERQRD--RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
+EGE + RR+ER R + + R +ER+RK +++++ + ++ ERK +++E+ R+E
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
Query: 279 DKKRK 283
++ +
Sbjct: 1735 TEQEQ 1739
Score = 95.1 bits (235), Expect = 6e-20
Identities = 75/274 (27%), Positives = 140/274 (51%), Gaps = 53/274 (19%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE---------RRRKEKETNRNRDRE 116
GQ + D + RE +++ ++ E+++ ++RDR+ R+ +E++ +RDR+
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
+ E + +E E+Q+ R +ERDR E + R +ERER+ ++ R E ER+ E
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 177 REKQKERETERDRDRQR--------DTEKERERQTDRERDRQRKTQTE------------ 216
+ ++E E E+ R ++R ERE Q R ++R RK + E
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 217 RQRETDREGERETDRRRERQRDRDRGKERD--------------------RERDRK---E 253
R +E+DR+ E R+ER+ + R ++RD +ERDR+ E
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
Query: 254 ERKKERKKERKKERK-EKKKEEKRREDKKRKWGE 286
E+ ++K R++E++ +++E+KRR++++RK E
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Score = 94.4 bits (233), Expect = 1e-19
Identities = 63/229 (27%), Positives = 129/229 (56%), Gaps = 18/229 (7%)
Query: 73 DGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN-RDRE--------KQTEIER 123
D D + RE +++ ++ E+++ R ++RDR+ R +E++ R R+R+ ++ E+ER
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
E+Q +E E+++ R +ER R +E + + E++ R E +R+ E + ++ER
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER 1783
Query: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER----ETDRRRERQRDR 239
E ++ R ++ D + E Q +ER+ Q+ +R + E E+ E ++R ++RDR
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 240 DRGKERD---RERDRKEERK--KERKKERKKERKEKKKEEKRREDKKRK 283
E +E+ R+EE++ +E +++R++ER+ K +EE R +K +
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 93.2 bits (230), Expect = 2e-19
Identities = 62/239 (25%), Positives = 125/239 (52%), Gaps = 29/239 (12%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREK------QTEIERDRERE 128
+ +R + ++R + ++ R++ KR+ E R E+ R + E+ + E E+ RER
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Query: 129 K--------QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE-RERDREREK 179
K Q E + + + R R +E +R RQ ++++ +RE+E + +E +R +
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 180 QKERETERDRDRQRDTEKERERQTDR---------ERDRQRKTQTERQRE---TDREGER 227
Q+E E RD Q E++ ER R +R+RQ + + +QRE E E+
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 228 ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERK--KERKEKKKEEKRREDKKRKW 284
E RR+ R+R+++ + E+ ++ ER ++ ++E +E +E+++ +++R D+K +W
Sbjct: 818 EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Score = 92.8 bits (229), Expect = 3e-19
Identities = 59/223 (26%), Positives = 125/223 (56%), Gaps = 19/223 (8%)
Query: 77 RQRERDR-VREKTEKERDRDRKR-----DRERRRKEKETNRNRDREKQTEIERDREREKQ 130
R++ERDR RE+ ++ R ++R+R +++ RR+E E + + + E E+++ R ++
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Query: 131 KGR----------ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
+ R ERE + R +ERDR +E + + E++ R E++R+ E + +
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 181 KERETERDRDRQRDTE---KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237
+ERE ++ R +QRD + +E + Q + + R R+ + + R ++ +E RR E++
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
Query: 238 DRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
++ ++R +ER+RK + R+++++++R + E K +E K
Sbjct: 1865 WQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 92.4 bits (228), Expect = 4e-19
Identities = 64/286 (22%), Positives = 141/286 (49%), Gaps = 52/286 (18%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
+L S+ R + + +G R++E++ R + E E + R+++E+E R+
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 113 -------------------------RDREKQTEIERDREREKQ---KGRERERDRGRERE 144
RE+Q E ++RE++ + E+E+ R + RE
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 145 RDRD----------REKERERQTEKDRDGQRETETERERDREREKQKER-ETERDRDRQR 193
R+++ + +ER +Q +++ DG +E + R +R QK R + E +R R+R
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 194 DT--------EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
T E+ R+ Q + + + + ER++ +E ER+ + Q++ ++
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 246 DRERDRKEERKKERKKERKKERKE-----KKKEEKRREDKKRKWGE 286
+RE+ R++ER+++ +K++K ++KE ++ E++RR+++++K+ E
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Score = 92.4 bits (228), Expect = 4e-19
Identities = 59/236 (25%), Positives = 137/236 (58%), Gaps = 28/236 (11%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER------- 127
++ ++ + R R + +E + + D+ERRR +++ RD++ + ++E +R+R
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ---RRDQKWRWQLEEERKRRRHTLYA 891
Query: 128 ----------EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETE--TERERDR 175
E+Q +E E + RE ER++ R +E+ERQ ++ Q+E E ER++
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQRE-EREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 176 EREKQKERETERDRDRQRDTE----KERERQTDRERDRQRKTQTERQRETDREGERETDR 231
R +++ER+ +D+ Q+ E +E E++ +ER+++ + + E Q+E ++ E ++
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREK 1010
Query: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKER-KEKKKEEKRREDKKRKWGE 286
RR ++ +R K+ + +++ ++ ++ER+K R +ER ++ ++EE+ ++++++ GE
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Score = 92.0 bits (227), Expect = 5e-19
Identities = 78/258 (30%), Positives = 145/258 (56%), Gaps = 38/258 (14%)
Query: 67 QAHKDADGDDR--QRERDRVREKTEKERDR---DRK-RDRERRRKEKETNRNRDREKQTE 120
+ K+A DR Q E+ +RE+ E++R R DRK R+ E+ +E+E R +E+ +
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 121 IERDREREKQKGR----ERERDRGRERERDRDRE------KERERQTEKDRDGQ-RETE- 168
+ R +++GR E +R R +ERER +E +ERE+Q +DRD + RE E
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 169 --TERERDRE--REKQKERETERDR-----DRQRDTEKERERQTDRERDRQRKTQTERQR 219
+ +ERDR+ E+Q+ R ER+R ++Q E+ R+ + + + ++R+ Q ++
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 220 ETDREGERETDRRRERQRDRD------RGKERDRERDRKEERKKERKKERK--KERKEKK 271
E DR+ E + R ++RDR R +E +R+ +E++ ++++RK +E ++ +
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR 1541
Query: 272 KEEK---RREDKKRKWGE 286
++E+ RR+D+ RK+ E
Sbjct: 1542 RQERGQQRRQDRDRKFRE 1559
Score = 90.5 bits (223), Expect = 2e-18
Identities = 55/236 (23%), Positives = 129/236 (54%), Gaps = 27/236 (11%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+ +R R++ + + +++ +R++ +R+E E R + K E E R+++ ++ ++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 135 RERDRGRERERDRDREKER-ERQTEKDRDGQRETETERERDREREK------QKERETER 187
R++ +RE + +R ++R +R+ E++R Q E E+E+ RER K Q + E+E
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 188 D--------RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR------- 232
D R R+++ ++ R+ Q ++ R R+ + Q + + R+ + E RR
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 233 --RERQRDRDRGKERDRERDRKEERKKERKKERKKER---KEKKKEEKRREDKKRK 283
+ +R R R R R+++E + + +++++++R +E++KE++RR+ ++R+
Sbjct: 773 AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Score = 89.7 bits (221), Expect = 3e-18
Identities = 58/220 (26%), Positives = 121/220 (55%), Gaps = 10/220 (4%)
Query: 67 QAHKDADGDDRQRERDRVREKTEK----ERDRDRKRDRERRRKEKETNRNRDREKQTEIE 122
Q +D D R+ E+ R++ ++ E + R+++RER+ E+E ++R ++ E
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 123 RD--REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE--RERDRERE 178
+ERE+Q+ +ERDR E + R +ER+R+ + +E E + E +
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR--RRERQ 236
+Q++R+ ++ + R E+ ++R+ DR+R + + Q ++RE + +E DR R E Q
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 237 RDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
+ R + +ER D ++ R++E +++ ++ER K +E+++
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
Score = 89.7 bits (221), Expect = 3e-18
Identities = 60/238 (25%), Positives = 133/238 (55%), Gaps = 26/238 (10%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERR-RKEKETNRNRDREKQTEIERDRE--REKQK 131
++ Q+ R + RE+ E ++ +++R R+ R+E++ + R+ ++ ERDR+ E+Q+
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 132 GRERERDRGRERERDRDREKER------------ERQT----EKDRDGQRETETERERDR 175
R +ERDR + R +E ER +RQ E+ + ++E +R +DR
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 176 EREKQKERETERDRDRQRDTEKERER------QTDRERDRQRKTQTERQRETDREGERET 229
+R+ ++E + ++R+ Q+ + +ER+R Q R ++++RK + Q+ +EG+++
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 230 DRRRERQRDRDRGKERDRERDRKEERKKERK-KERKKERKEKKKEEKRREDKKRKWGE 286
+ R+R+ D ++RE + ++++RK E + + + +++E++ R D+ RK+ E
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Score = 88.6 bits (218), Expect = 6e-18
Identities = 63/227 (27%), Positives = 128/227 (56%), Gaps = 16/227 (7%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRE--RRRKEKETNRN-RDR---EKQTEIERDRERE 128
D++Q R +++ +ERDR + D + + R+E++ +R RDR E++ ++ R +ERE
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR-QERE 1658
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET----ERERDREREKQ--KE 182
+Q +R+R E + ++ E+++ R+ E+DR + E + ERER +E+Q +
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE--RETDRRRERQRDRD 240
+E ER + +E E++ R ++R RK E Q +RE + R +R R+ + +
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 241 RGKERDRERDRKEER-KKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+ER+ ++ R +E +K R++E+ ++ +E+++ ++ D K +W E
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Score = 88.2 bits (217), Expect = 8e-18
Identities = 65/239 (27%), Positives = 133/239 (55%), Gaps = 19/239 (7%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQ-TEIERDR 125
Q K + + R R ++R R K KE + R ++RE++ ++ + R+ E+Q + ERDR
Sbjct: 1372 QGRKFLEEEQRLRRQERER-KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 126 E--REKQKGRERERDRG-----RERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
+ E+Q+ R +ER+R ++ ++R R+ E Q ++R+ Q+ ER+R E
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 179 KQKERETERDRD------RQRDTEK---ERERQTDRERDRQRKTQTERQ-RETDREGERE 228
+Q+ R ERDR R ++ E+ E E+Q R++ +++ Q E+Q R +R +R
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 229 TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
DR R+ + + +ER+ ++ ++ER ++ + E +K R+++++ + ++++ + EG
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Score = 87.8 bits (216), Expect = 1e-17
Identities = 52/223 (23%), Positives = 117/223 (52%), Gaps = 8/223 (3%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Q K + ++ +R++ E+ E+ R + +R+++ RR+++ + + ++R+ E
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE----REKQKE 182
E+++ E ++ + RER + R + + Q E + D ++ R R +E R++Q+E
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
+ R+ + Q E+ RQ E R+ T + E G + R + R+R
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER- 796
Query: 243 KERDRERDRKEER---KKERKKERKKERKEKKKEEKRREDKKR 282
+ R ER ++E+R ++E K++R+++R+E++KE + E++++
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Score = 84.7 bits (208), Expect = 8e-17
Identities = 64/245 (26%), Positives = 129/245 (52%), Gaps = 42/245 (17%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREK------QTEIERDREREKQ 130
R+ E +R+ ++ ++E + +R R++E +E+E R R + + Q E E D + K
Sbjct: 661 REEEEERLEQRLKREHEEER-REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 131 KGRERERDRGRERERDRDREKERERQT---EKDRDGQRETETERERDREREKQKERETER 187
R R+++ R R+ ++ + RE + E++R +++ E E+ RD + Q E ++ER
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Query: 188 DRDR---------QRDTE---KERERQTDR------ERDRQRKTQTERQRETD-REGERE 228
R R QR+ + +ER+++ R E++++R+ + ER++E E E +
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 229 TDRRRERQ--RDRDRGKERDRERDRKEERKKERK------KERKKER-----KEKKKEEK 275
RR Q ++ + G + D+ER R +E+++++K +ERK+ R K +E+
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 276 RREDK 280
R+E +
Sbjct: 900 RKEQQ 904
Score = 84.3 bits (207), Expect = 1e-16
Identities = 59/232 (25%), Positives = 125/232 (53%), Gaps = 29/232 (12%)
Query: 76 DRQRERDRVREKTEKER--------DRDRKRDRERRRKEKETNRNRDREKQTE--IERDR 125
+ +RE+ RE+ E+ER +++ +R ++ RR+++E R + ++ E +E+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 126 EREKQKGRERERDRGRERERDRDREKER----ERQTEKDRDGQ--------RETETERER 173
+RE ++ R + E+E+ R+R K R + Q E + D + R+ E +R R
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 174 DREREKQKERET-----ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERE 228
+ EK++ RE+ E +R ++ E+E+ R + + K++ RQR + R RE
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Query: 229 TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERK--EKKKEEKRRE 278
R+ R +R + ++R + ++E+++ +++ER+KE + E++++ +RRE
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Score = 79.3 bits (194), Expect = 4e-15
Identities = 57/181 (31%), Positives = 99/181 (54%), Gaps = 14/181 (7%)
Query: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
D EK+ D + + R +E D+ R RDR E+E ++ R ++E E E
Sbjct: 96 DEEKRARC--DGKESLLQDRRQEEDQRRFEPRDRQLEEE---PGQRRRQKRQEQERELAE 150
Query: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ----RETDREGERET 229
E+ +++ER +RDR R RD E R+RQ +ER+ +R + + Q ET+ + E
Sbjct: 151 GEEQSEKQERLEQRDRQR-RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 230 DRRRE----RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWG 285
RRRE R++ R+ +++ RER + +++E K+ RK+E +K+EEK +E++ ++
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 286 E 286
E
Sbjct: 270 E 270
Score = 67.4 bits (163), Expect = 1e-11
Identities = 39/153 (25%), Positives = 83/153 (54%), Gaps = 5/153 (3%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
+RE ++R + + R+ ++ R+ R +++ ++ DR+ + E + +ERE+Q+ R ++R
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETET-----ERERDREREKQKERETERDRDRQ 192
D E ++ + +E+E++ ++RD Q E E+ R E+E +E E +R ++R+
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Query: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREG 225
R +E R+ +E R R+ + +E G
Sbjct: 1878 RKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHG 1910
Score = 51.2 bits (121), Expect = 1e-06
Identities = 30/113 (26%), Positives = 65/113 (57%), Gaps = 8/113 (7%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Q + + D + RE +++R++ E+++ R ++RD + R +E++ ++E++ ERDR+
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE-EQEQRLRQERDRQ 1844
Query: 127 -------REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
++K R E++ +E E+ R +E+ER+ + E R Q+E + R+
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 117 bits (293), Expect = 1e-26
Identities = 72/210 (34%), Positives = 108/210 (51%), Gaps = 13/210 (6%)
Query: 74 GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
GD + R D + K + + E + K ++ DR+++ + E+ E++K R
Sbjct: 202 GDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
ERER+ ERER R RE+E ER+ E+ RD +R R+R R R + R ++R R R
Sbjct: 262 ERERE---ERERKRRREEE-EREKERARDRER-----RKRSRSRSRHSSRTSDRRCSRSR 312
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR----DRGKERDRER 249
D ++ R R+ R R R R+ R + R DRRR + RDR R K RDRE+
Sbjct: 313 DHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQ 372
Query: 250 DRKEERKKERKKERKKERKEKKKEEKRRED 279
DRK + K++R + KK + EK+ ED
Sbjct: 373 DRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Score = 111 bits (278), Expect = 6e-25
Identities = 63/176 (35%), Positives = 98/176 (55%), Gaps = 17/176 (9%)
Query: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
E + + R++ E +RD +K+K ER++ RERER+ E+ER+R+ E++ E
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEE-----ER 279
Query: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD--RQRKTQTERQRETDREG 225
E ER RDRER K R R R R + + +R+ R RD R R + R R DR
Sbjct: 280 EKERARDRERRK-------RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
Query: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
R DR + R R R + R + RDRK + + + ++R+++RK K+KE++ +DKK
Sbjct: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
Score = 105 bits (263), Expect = 4e-23
Identities = 55/182 (30%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDR-KRDRERRRKEKETNRNRDREKQTEIERDRERE 128
++ D D+R ++ + RE+ EKER+R+R +R+R+RRR+E+E + R R+++ R R R
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE---RRKRSRS 295
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
+ + R DR R RD R + RER+ + RD +R +R + R + ++R +
Sbjct: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
RDR+ + K R + DRE+DR+ K + +R + + + R ++ + KE D +
Sbjct: 356 RDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
Query: 249 RD 250
+
Sbjct: 414 NE 415
Score = 104 bits (259), Expect = 1e-22
Identities = 69/207 (33%), Positives = 99/207 (47%), Gaps = 36/207 (17%)
Query: 77 RQRERDR-VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
R E DR R K EK+ +R+++RER R+E+E R R+ E EREK++ R+R
Sbjct: 237 RTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE---------EREKERARDR 287
Query: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
ER R+R R R R R DR R + +R R RER + + R+ R R R
Sbjct: 288 ER---RKRSRSRSRHSSR----TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEER 255
K R R DR R + R DR+ + R + R +E+DR+ KE+R
Sbjct: 341 RKHRSRSRDRRRSKSR------------------DRKSYKHRSKSRDREQDRKSKEKEKR 382
Query: 256 KKERKKER-KKERKEKKKEEKRREDKK 281
+ KK K +EK+ E+ E K+
Sbjct: 383 GSDDKKSSVKSGSREKQSEDTNTESKE 409
Score = 95.9 bits (237), Expect = 4e-20
Identities = 47/150 (31%), Positives = 81/150 (54%), Gaps = 10/150 (6%)
Query: 141 RERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERE 200
+E+ R R E +R+ + +K++ + E E ERER+RE ++K R E +R+++R ++ER
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 201 RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
+ R R R R + R R + + R RER+R R R + R R DR E + + R
Sbjct: 291 K---RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
Query: 261 KERKKER-------KEKKKEEKRREDKKRK 283
++R++ + K + K R +D+K K
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Score = 60.8 bits (146), Expect = 1e-09
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
SR R S+ S R + HK + +R+R R R R ++ + DR ++ R R R ++
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS-RSHDRSERKHRSRSR-DRRR 352
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
+++RDR+ + R+RE+ + + + RG + ++ + RE+Q+E +E++T
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 170 ERE 172
+ E
Sbjct: 413 KNE 415
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 19/133 (14%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
DR+ R R K + R+R R R R+RRR +R+ DR ++ R R+R + K R+R
Sbjct: 305 DRRCSRSR-DHKRSRSRERRRSRSRDRRR-----SRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 136 E----RDRGRERERDRDREKERERQTEKD-----RDGQRETETERERDREREKQKERE-- 184
+ R + R+RE+DR + KE+E++ D + G RE ++E +E + E
Sbjct: 359 KSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 185 -TERDRDRQRDTE 196
T D + DT+
Sbjct: 418 GTSEDIKSEGDTQ 430
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 117 bits (293), Expect = 1e-26
Identities = 72/210 (34%), Positives = 108/210 (51%), Gaps = 13/210 (6%)
Query: 74 GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
GD + R D + K + + E + K ++ DR+++ + E+ E++K R
Sbjct: 202 GDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKER 261
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
ERER+ ERER R RE+E ER+ E+ RD +R R+R R R + R ++R R R
Sbjct: 262 ERERE---ERERKRRREEE-EREKERARDRER-----RKRSRSRSRHSSRTSDRRCSRSR 312
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR----DRGKERDRER 249
D ++ R R+ R R R R+ R + R DRRR + RDR R K RDRE+
Sbjct: 313 DHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQ 372
Query: 250 DRKEERKKERKKERKKERKEKKKEEKRRED 279
DRK + K++R + KK + EK+ ED
Sbjct: 373 DRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Score = 111 bits (278), Expect = 6e-25
Identities = 63/176 (35%), Positives = 98/176 (55%), Gaps = 17/176 (9%)
Query: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
E + + R++ E +RD +K+K ER++ RERER+ E+ER+R+ E++ E
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEE-----ER 279
Query: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD--RQRKTQTERQRETDREG 225
E ER RDRER K R R R R + + +R+ R RD R R + R R DR
Sbjct: 280 EKERARDRERRK-------RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
Query: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
R DR + R R R + R + RDRK + + + ++R+++RK K+KE++ +DKK
Sbjct: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKK 388
Score = 105 bits (263), Expect = 4e-23
Identities = 55/182 (30%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDR-KRDRERRRKEKETNRNRDREKQTEIERDRERE 128
++ D D+R ++ + RE+ EKER+R+R +R+R+RRR+E+E + R R+++ R R R
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE---RRKRSRS 295
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
+ + R DR R RD R + RER+ + RD +R +R + R + ++R +
Sbjct: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
RDR+ + K R + DRE+DR+ K + +R + + + R ++ + KE D +
Sbjct: 356 RDRK--SYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTK 413
Query: 249 RD 250
+
Sbjct: 414 NE 415
Score = 104 bits (259), Expect = 1e-22
Identities = 69/207 (33%), Positives = 99/207 (47%), Gaps = 36/207 (17%)
Query: 77 RQRERDR-VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
R E DR R K EK+ +R+++RER R+E+E R R+ E EREK++ R+R
Sbjct: 237 RTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEE---------EREKERARDR 287
Query: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
ER R+R R R R R DR R + +R R RER + + R+ R R R
Sbjct: 288 ER---RKRSRSRSRHSSR----TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEER 255
K R R DR R + R DR+ + R + R +E+DR+ KE+R
Sbjct: 341 RKHRSRSRDRRRSKSR------------------DRKSYKHRSKSRDREQDRKSKEKEKR 382
Query: 256 KKERKKER-KKERKEKKKEEKRREDKK 281
+ KK K +EK+ E+ E K+
Sbjct: 383 GSDDKKSSVKSGSREKQSEDTNTESKE 409
Score = 95.9 bits (237), Expect = 4e-20
Identities = 47/150 (31%), Positives = 81/150 (54%), Gaps = 10/150 (6%)
Query: 141 RERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERE 200
+E+ R R E +R+ + +K++ + E E ERER+RE ++K R E +R+++R ++ER
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 201 RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
+ R R R R + R R + + R RER+R R R + R R DR E + + R
Sbjct: 291 K---RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRS 347
Query: 261 KERKKER-------KEKKKEEKRREDKKRK 283
++R++ + K + K R +D+K K
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Score = 60.8 bits (146), Expect = 1e-09
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
SR R S+ S R + HK + +R+R R R R ++ + DR ++ R R R ++
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS-RSHDRSERKHRSRSR-DRRR 352
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETET 169
+++RDR+ + R+RE+ + + + RG + ++ + RE+Q+E +E++T
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 170 ERE 172
+ E
Sbjct: 413 KNE 415
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 19/133 (14%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
DR+ R R K + R+R R R R+RRR +R+ DR ++ R R+R + K R+R
Sbjct: 305 DRRCSRSR-DHKRSRSRERRRSRSRDRRR-----SRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 136 E----RDRGRERERDRDREKERERQTEKD-----RDGQRETETERERDREREKQKERE-- 184
+ R + R+RE+DR + KE+E++ D + G RE ++E +E + E
Sbjct: 359 KSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 185 -TERDRDRQRDTE 196
T D + DT+
Sbjct: 418 GTSEDIKSEGDTQ 430
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 115 bits (287), Expect = 6e-26
Identities = 63/207 (30%), Positives = 122/207 (58%), Gaps = 10/207 (4%)
Query: 72 ADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
AD D+ ++R R + + +R RKR E R+ +E + EK ++ +K
Sbjct: 439 ADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLD-------EK 491
Query: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
E+ E R+R+REKERER+ E +++ ++E E ERE+DRER+++KE+E E+++++
Sbjct: 492 LGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE--- 248
QR+ EKER+++ ++E +RQ++ + E Q+ ++E E E ++ RE+ ++ +E + E
Sbjct: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMV 611
Query: 249 RDRKEERKKERKKERKKERKEKKKEEK 275
++ E +++E R++ + EK
Sbjct: 612 EKQESENSCNKEEEPVFTRQDSNRSEK 638
Score = 105 bits (261), Expect = 6e-23
Identities = 58/192 (30%), Positives = 112/192 (58%), Gaps = 3/192 (1%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
Q+S S + +A K + ++R+ E R EK + D K ++ E R R+RE
Sbjct: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE 510
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
K+ E E++ E+E+++ RE+ER+ ++RER +++EKE E++ EK R+ ++E + E+E++ E
Sbjct: 511 KEREREKELEKEQEQEREKERE--KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE 568
Query: 177 REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
R+K+KE+E ++ ++++++ E E+ER+ E+ R+ E E +E E ++ E
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE-KQESENSCNKEEEPV 627
Query: 237 RDRDRGKERDRE 248
R ++E
Sbjct: 628 FTRQDSNRSEKE 639
Score = 102 bits (253), Expect = 5e-22
Identities = 59/214 (27%), Positives = 120/214 (56%), Gaps = 8/214 (3%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
DRQ R K++ D ++RR+++ E +ER R+R +++ R
Sbjct: 421 DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQS-------EISAAVERARKRREEEERRM 473
Query: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
E R R E+ EK + E ERE++REREK+ E+E E++R+++R+
Sbjct: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK 533
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEER 255
++ER+++ ++E +++++ Q E ++E +E E+E +R++E++++ + KE+++E + ++ER
Sbjct: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Query: 256 KK-ERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
+K E K E ++ E E++ E+ K E +
Sbjct: 594 EKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Score = 93.6 bits (231), Expect = 2e-19
Identities = 50/154 (32%), Positives = 97/154 (62%), Gaps = 14/154 (9%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
R+RER++ RE+ EKE +++++++RE+ R+ +DRE+Q E E++ E+E++K RE E
Sbjct: 505 REREREKERER-EKELEKEQEQEREKERE-------KDRERQQEKEKELEKEQEKQREME 556
Query: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE------TERDRD 190
++R +E+E++ +R+KE+E++ +K ++ ++E E E+ER++ EK + RE E+
Sbjct: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQES 616
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDRE 224
++E T ++ +R K T ET+ E
Sbjct: 617 ENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
Score = 90.9 bits (224), Expect = 1e-18
Identities = 43/167 (25%), Positives = 105/167 (62%), Gaps = 4/167 (2%)
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
D + ++ R ++ + ER R R +E ER+ E+ R + +R ++ +K+
Sbjct: 440 DEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQP 499
Query: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243
E R+R+R+ E+ERE++ ++E++++R E++RE DRE ++E ++ E+++++ R
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQER----EKEREKDRERQQEKEKELEKEQEKQREM 555
Query: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
E++R++++++E +++++KE++ ++ +++++E E ++ K E I P
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602
Score = 78.6 bits (192), Expect = 6e-15
Identities = 51/155 (32%), Positives = 91/155 (58%), Gaps = 6/155 (3%)
Query: 47 LDFSRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDRVREKTEKERDRDRKRDRERRRK 105
LD G L Q SP + K+ + + + ++E+++ REK E+E+DR+R++++E +
Sbjct: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREK-EREKDRERQQEKE-KEL 545
Query: 106 EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK--DRDG 163
EKE + R+ EK+ + E+++E E+QK +E+E + +E+E++ + EKERE+ EK R+
Sbjct: 546 EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREP 605
Query: 164 QRETETERERDREREKQKERETERDRDRQRDTEKE 198
E E++ + E KE E R +EKE
Sbjct: 606 NLEPMVEKQ-ESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 41.6 bits (96), Expect = 8e-04
Identities = 45/206 (21%), Positives = 79/206 (38%), Gaps = 14/206 (6%)
Query: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
D +RE +E + + R E R + D Q+ +++ + ER
Sbjct: 861 DFIRESSEAQVQKFLSRSVEDVRPH-----HTDANNQSACFEAPDQKTLSAPQEERISAV 915
Query: 142 ERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERER 201
E + R R + D QR E K R + +R EK ++
Sbjct: 916 ESQPSRKRSVSHGSNHTQKPDEQRS-----EPSAGIPKVTSRCIDSKEPIERPEEKPKKE 970
Query: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK----ERDRERDRKEERKK 257
R + + + + + R G R + RRE DR + ++ RD KEER++
Sbjct: 971 GFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQ 1030
Query: 258 ERKKERKKERKEKKKEEKRREDKKRK 283
++KE +K K +K + E ++K
Sbjct: 1031 RKEKEGEKAEKVTEKVVVKPEKTEKK 1056
Score = 32.7 bits (73), Expect = 0.38
Identities = 47/213 (22%), Positives = 83/213 (38%), Gaps = 26/213 (12%)
Query: 92 RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
RD + RD + R + + R RE+ R + + +R R RG E + D +
Sbjct: 1216 RDYPQYRDNKPRAEHIPSGPLRQREESE--TRSESSDFEVVPKRRRQRGSETDTD---SE 1270
Query: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
E ++KD + + ER ++ K + + + R + E+ R+ D+ +
Sbjct: 1271 IHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAK 1330
Query: 212 K------TQTERQR-ETDREGERETDRRRERQRDRDRGKERDR-------ERDRKEERKK 257
T R R T R G R+ R R R RD E + E+ +
Sbjct: 1331 PGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEP 1390
Query: 258 ERKKER-------KKERKEKKKEEKRREDKKRK 283
R+ E+ K+ K ++K + RE +R+
Sbjct: 1391 PRRHEQFIPIAADKRPPKFERKFDPARERPRRQ 1423
Score = 30.4 bits (67), Expect = 1.9
Identities = 41/171 (23%), Positives = 63/171 (36%), Gaps = 24/171 (14%)
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD---------RE 176
+ EKQ + +D ER R R ++ T R +E RERD R
Sbjct: 1133 KEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEA---RERDWFPDQGYRGRG 1189
Query: 177 REKQKERETE-------RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERET 229
R + R R R + T + + ++ R + RQRE +
Sbjct: 1190 RGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESS 1249
Query: 230 DRRRERQRDRDRGKERDRERDRKE-----ERKKERKKERKKERKEKKKEEK 275
D +R R RG E D + + E + + K +++ER E KK K
Sbjct: 1250 DFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVK 1300
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 114 bits (286), Expect = 8e-26
Identities = 71/213 (33%), Positives = 115/213 (53%), Gaps = 21/213 (9%)
Query: 91 ERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDR-DR 149
+ R +R++ER +E+ R R+ E++ +RE ++ K RE R R R R+R R +R
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKER 1188
Query: 150 EKERERQTEKDRDGQRETETERERDREREK-----------------QKERE-TERDRDR 191
K +E+++EK Q E + D R+ QKE E ER ++R
Sbjct: 1189 AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKER 1248
Query: 192 Q-RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG-KERDRER 249
+ R E+E E Q +RE++ +R+ + +RE RE RE DR RER+R+RDRG ++RDRER
Sbjct: 1249 EKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRER 1308
Query: 250 DRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
DR+ R+++R+ ++ R + R +R
Sbjct: 1309 DRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 112 bits (281), Expect = 3e-25
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 32/205 (15%)
Query: 78 QRERDR-VREK-TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
QRE++R VRE+ E+ER+ +R RER R E+E +R++ RE R R+R R +
Sbjct: 1135 QREQERAVREQWAEREREMER---RERTRSEREWDRDKVREGPRSRSRSRDR-----RRK 1186
Query: 136 ERDRGRERERDRDREKERERQTEKDRDGQRET-------------------ETER-ERDR 175
ER + +E++ ++ + + E + D R+T E ER ER +
Sbjct: 1187 ERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAK 1246
Query: 176 EREK-QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
EREK +KE+E E ++R+++ E+ER RQ +RE+ R+ + +R+RE +RE +R DR R+
Sbjct: 1247 EREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDR-GDRDRD 1305
Query: 235 RQRDRDRGKERDRERDRKEERKKER 259
R+RDR+RG+ERDR ++ R + R
Sbjct: 1306 RERDRERGRERDRRDTKRHSRSRSR 1330
Score = 104 bits (259), Expect = 1e-22
Identities = 73/202 (36%), Positives = 110/202 (54%), Gaps = 40/202 (19%)
Query: 76 DRQRERDRVREKTEKERD----------RDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
+R+RE +R RE+T ER+ R R R R+RRRKE+ ++ + EK+ + + +
Sbjct: 1148 EREREMER-RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEP 1206
Query: 126 ERE-------KQKGR--------------ERERDRGRERERDRDREKERERQTEKDRDGQ 164
+ K K ++E +R ER ++REK R+ Q E+++ +
Sbjct: 1207 PAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERA---ERAKEREKRRKEQEEEEQK-E 1262
Query: 165 RETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDRE 224
RE E ERER+R+ E++K RE R+RDR+R+ E+ER+R DR+RDR+R ER RE DR
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDR-GDRDRDRER--DRERGRERDRR 1319
Query: 225 GERETDRRRERQRD-RDRGKER 245
+ R R R RDRG R
Sbjct: 1320 DTKRHSRSRSRSTPVRDRGGRR 1341
Score = 81.6 bits (200), Expect = 7e-16
Identities = 58/183 (31%), Positives = 90/183 (49%), Gaps = 32/183 (17%)
Query: 59 SPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKR------------DRERRRK- 105
S R W + + R R+R R KE+ ++K D R+ K
Sbjct: 1161 SEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKA 1220
Query: 106 ---------------EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE 150
+KE R +R K+ E +R +E+E+++ +ERE++ RER R +RE
Sbjct: 1221 APCIYWLPLTDSQIVQKEAER-AERAKERE-KRRKEQEEEEQKEREKEAERERNRQLERE 1278
Query: 151 KERERQTEKDRDGQRETETER-ERDREREKQKERETERDRDRQRDTEKERERQTD-RERD 208
K RE E+DR+ +RE E +R +RDR+RE+ +ER ERDR + + R R T R+R
Sbjct: 1279 KRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRG 1338
Query: 209 RQR 211
+R
Sbjct: 1339 GRR 1341
Score = 57.0 bits (136), Expect = 2e-08
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 35/135 (25%)
Query: 186 ERDRDRQRDTEKE-RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
+ R QR+ E+ RE+ +RER+ +R+ +T +RE DR+ RE R R R RDR R KE
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRR-KE 1187
Query: 245 RDRERDRKEERKKERK---------------------------------KERKKERKEKK 271
R + +++K E+K++ + KE ++ + K+
Sbjct: 1188 RAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKE 1247
Query: 272 KEEKRREDKKRKWGE 286
+E++R+E ++ + E
Sbjct: 1248 REKRRKEQEEEEQKE 1262
Score = 55.1 bits (131), Expect = 7e-08
Identities = 44/206 (21%), Positives = 88/206 (42%), Gaps = 27/206 (13%)
Query: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163
R E E +R+ R+ + E + + +K R+ ER R R+ + E + E++ D
Sbjct: 193 RPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQ 252
Query: 164 QRETETERER-DR-----EREKQKERETERDRDRQRDTEKERERQT-------------- 203
+ + R R DR E E+++E E E D + + D E ++ R+
Sbjct: 253 ETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIP 312
Query: 204 ----DRERDRQRKTQTERQRETDREG---ERETDRRRERQRDRDRGKERDRERDRKEERK 256
+ D + KT+++ Q +R G + + R+ + + KE +EE +
Sbjct: 313 RVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEER 372
Query: 257 KERKKERKKERKEKKKEEKRREDKKR 282
+ + + KE+ + + ED+K+
Sbjct: 373 EIKSSQGLKEKSKSPSPPRLTEDRKK 398
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Query: 58 ESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE--RRRKEKETNR-NRD 114
E R+ L + + +R RER+R RE+ +RDRDR+RDRE R R ++T R +R
Sbjct: 1268 ERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRS 1327
Query: 115 REKQTEIERDR 125
R + T + RDR
Sbjct: 1328 RSRSTPV-RDR 1337
Score = 42.0 bits (97), Expect = 6e-04
Identities = 36/165 (21%), Positives = 71/165 (43%), Gaps = 9/165 (5%)
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
Q G E ++ ++ ++ +E R+R + R+ E E + E + +
Sbjct: 126 QIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPP 185
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER 249
D Q E+ E + R R+ + +E + ++D E R+ +RR R R K + +
Sbjct: 186 DFQSSLERP-ELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQ 244
Query: 250 DRKEERKKE--------RKKERKKERKEKKKEEKRREDKKRKWGE 286
+EE +E R K +E+++EE+ ED + + G+
Sbjct: 245 PAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGD 289
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 14/186 (7%)
Query: 48 DFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEK 107
D + R G + S R A + E D+ DR E +E+
Sbjct: 217 DDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEE 276
Query: 108 ETNRNRDREKQTEIERDRERE-------KQKGRERERDRGRER--ERDRDREKERERQTE 158
E D E++ + E + RE K++G E R + E ER + R +E+E
Sbjct: 277 EEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER 336
Query: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
R + + E + ++++KE +T + E+ERE ++ + + K+ + +
Sbjct: 337 GGRFTRSQEEARKSHLARQQQEKEMKTTSPLE-----EEEREIKSSQGLKEKSKSPSPPR 391
Query: 219 RETDRE 224
DR+
Sbjct: 392 LTEDRK 397
Score = 37.7 bits (86), Expect = 0.012
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 25/101 (24%)
Query: 208 DRQRKTQTERQR----------------ETDREGERETDRR-RERQRDRDRGKER-DRER 249
DR +T+TE Q + R +RE +R RE+ +R+R ER +R R
Sbjct: 1101 DRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTR 1160
Query: 250 DRKE-------ERKKERKKERKKERKEKKKEEKRREDKKRK 283
+E E + R + R + RKE+ K ++++ +KK K
Sbjct: 1161 SEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEK 1201
Score = 35.8 bits (81), Expect = 0.045
Identities = 34/186 (18%), Positives = 62/186 (33%), Gaps = 3/186 (1%)
Query: 86 EKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER 145
E+ E R R ++ +++ +R + R R R R R ++R
Sbjct: 553 EQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQR 612
Query: 146 DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR--QRDTEKERERQT 203
D + + + + G R T R R R R + + + RD+
Sbjct: 613 DVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETK 672
Query: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263
D ++ T Q + ER T + R + E+ + + ER +
Sbjct: 673 DPSSGQEVATPPVPQLQVCEPKER-TSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPK 731
Query: 264 KKERKE 269
K E +E
Sbjct: 732 KCEAEE 737
Score = 32.0 bits (71), Expect = 0.65
Identities = 29/144 (20%), Positives = 46/144 (31%), Gaps = 20/144 (13%)
Query: 148 DREKERERQTEKDRDGQ------RETETERERDREREKQKERETERDRDRQRDT------ 195
D +++ + E DR Q E + E KQ E + R
Sbjct: 511 DYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRL 570
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD--------RDRGKERDR 247
++ + + R + R R D G R R +QRD RG+ +
Sbjct: 571 KQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMG 630
Query: 248 ERDRKEERKKERKKERKKERKEKK 271
R E R + R + R +K
Sbjct: 631 SRSTSESRSRSRSRSRSASSNSRK 654
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 110 bits (275), Expect = 1e-24
Identities = 63/162 (38%), Positives = 94/162 (58%), Gaps = 4/162 (2%)
Query: 64 GLGQAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIE 122
G G +++ + RQRER V K + + D + R E RR+E+E RN RE+ +
Sbjct: 2073 GKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
Query: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
R+ +R + K R+ DR RER +RDRE+E +R E DR +R ERERDR R++ +
Sbjct: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQ--RKTQTERQRETD 222
R ERDRD+ RD E+ R+R+ DR + ++ R + E R +D
Sbjct: 2193 RSRERDRDKARDRERGRDRK-DRSKSKESARDPKPEASRASD 2233
Score = 104 bits (260), Expect = 8e-23
Identities = 63/173 (36%), Positives = 91/173 (52%), Gaps = 17/173 (9%)
Query: 111 RNRDREKQTEIERDRER----EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRE 166
+ + QT R RER K+K E +GR E DR RE+ER R ++RD R
Sbjct: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRERDWDRP 2132
Query: 167 TETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226
E +R RD++ + +R ER +R R+ E +R ++ DR R+R R + ER R DR
Sbjct: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR--- 2189
Query: 227 RETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
DR R R+RDRD+ ++R+R RDRK+ K K+ ++ K E R D
Sbjct: 2190 ---DRSRSRERDRDKARDRERGRDRKDRSKS------KESARDPKPEASRASD 2233
Score = 104 bits (259), Expect = 1e-22
Identities = 54/153 (35%), Positives = 88/153 (57%), Gaps = 3/153 (1%)
Query: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190
KG E R+R+R +E+ E+ D Q +R R+RER + RE + DR
Sbjct: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEP-DAQGRASEDRRRERERGRNWSRERDWDRP 2132
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDR--EGERETDRRRERQRDRDRGKERDRE 248
R+ D ++++ D +R+R+R +R+RE DR E +R +R R R+R+RDR ++RDR
Sbjct: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
Query: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
R R+ +R K R +ER ++RK++ K ++ D K
Sbjct: 2193 RSRERDRDKARDRERGRDRKDRSKSKESARDPK 2225
Score = 100 bits (249), Expect = 1e-21
Identities = 66/186 (35%), Positives = 94/186 (50%), Gaps = 21/186 (11%)
Query: 72 ADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
A D R+ + R +T + R R+R + + +E + Q DR RE
Sbjct: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEP------DAQGRASEDRRRE--- 2116
Query: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
RER R+ RER+ DR RE +R R + RD R E RDRERE + +E +R R+R
Sbjct: 2117 -RERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRER 2175
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
R+ E+ER+R+ DR+R R R ER R+ R+ ER DR +DR K ++ RD
Sbjct: 2176 SRNRERERDRRRDRDRSRSR----ERDRDKARDRERGRDR-------KDRSKSKESARDP 2224
Query: 252 KEERKK 257
K E +
Sbjct: 2225 KPEASR 2230
Score = 68.9 bits (167), Expect = 5e-12
Identities = 35/125 (28%), Positives = 70/125 (56%), Gaps = 1/125 (0%)
Query: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
K + + +T R+R+R KE+ E + D Q ++R R+ +R R+ R+ +R
Sbjct: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
Query: 219 RETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
RE DR ++++ R +R R+R ++R+RE DR +E + R++ R +ER+ ++ ++ R
Sbjct: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
Query: 279 DKKRK 283
+ +
Sbjct: 2193 RSRER 2197
Score = 61.6 bits (148), Expect = 8e-10
Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 31/127 (24%)
Query: 51 RGRLGSQES----PRSWGLGQAHKDADGD-------------DRQRERDRVRE-KTEKER 92
RGR S+E PR W H+D D DR+RE DR +E +ER
Sbjct: 2119 RGRNWSRERDWDRPREW---DRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRER 2175
Query: 93 DRDRKRDRERRR-KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
R+R+R+R+RRR +++ +R RDR+K RDRER GR+R +DR + +E RD +
Sbjct: 2176 SRNRERERDRRRDRDRSRSRERDRDK----ARDRER----GRDR-KDRSKSKESARDPKP 2226
Query: 152 ERERQTE 158
E R ++
Sbjct: 2227 EASRASD 2233
Score = 39.3 bits (90), Expect = 0.004
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 22/90 (24%)
Query: 198 ERERQTDRERDRQRKTQTERQR---ETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
E QT R R+R +++ E D +G DRRRER+R R+ +ERD +R R+ +
Sbjct: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
Query: 255 RKKERKKERKKERKEKKKEEKRREDKKRKW 284
R +++ D R W
Sbjct: 2137 RHRDK-------------------DSSRDW 2147
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 107 bits (268), Expect = 9e-24
Identities = 67/249 (26%), Positives = 119/249 (47%), Gaps = 28/249 (11%)
Query: 70 KDADGDDRQRERDRVREKTE---KERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
++++ DD+ + + + R K++ K +++ + ++R+ + E R R R K + E +E
Sbjct: 440 RNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499
Query: 127 REKQ---KGRERERDRGRERERD---RDREKERERQTEKDRDGQ-RETETE--------- 170
+EKQ KG+++ER R +E+ + + E + + EKDR Q R E +
Sbjct: 500 KEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN 559
Query: 171 ---RERDREREKQKE-RETERDRDRQRDTEKERERQTD-----RERDRQRKTQTERQRET 221
RER R R++ + R DRDR R E R R+ + R R R+R+T R R
Sbjct: 560 SRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK 619
Query: 222 DREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
DR R R ER+ + R K++ R ++ K +KE + K+ + + ++
Sbjct: 620 DRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSRE 679
Query: 282 RKWGEGISP 290
+K SP
Sbjct: 680 KKADRDQSP 688
Score = 105 bits (261), Expect = 6e-23
Identities = 71/229 (31%), Positives = 125/229 (54%), Gaps = 22/229 (9%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRR-KEKETNRNRDRE-KQTEIERDRER 127
KD + ++R+ R EK +K +++ +KR + + R K KE +++++R+ K E R R
Sbjct: 427 KDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMR 486
Query: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER 187
+ KGR+ E + +E++ D + K++ER K++ Q E+++ E D + K+K+R +
Sbjct: 487 SRSKGRDHENVKEKEKQSD-SKGKDQERSRSKEKSKQLESKSN-EHDHSKSKEKDRRAQ- 543
Query: 188 DRDRQRDTEK------ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
R R+ D K R R+ R RDR R+ ++ R + DR +E R RE Q R R
Sbjct: 544 SRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS-RTHDRDRSRSKEYHRYRE-QEYRRR 601
Query: 242 GKERDRE------RDRKEERKKERKKERKKERKE---KKKEEKRREDKK 281
G+ R RE R R ++R++ R+ R ER+E + K++ R ++ K
Sbjct: 602 GRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESK 650
Score = 94.7 bits (234), Expect = 8e-20
Identities = 61/245 (24%), Positives = 126/245 (51%), Gaps = 18/245 (7%)
Query: 59 SPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQ 118
S W G + + + QR RV+E+ + + + KEK+ ++ K+
Sbjct: 376 SGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKE 435
Query: 119 TEIERDRERE-KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE-RDRE 176
+I R+ E++ K K + ++R + + R + +++ K +ER ++ +R+ ++ + + RD E
Sbjct: 436 RDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHE 495
Query: 177 REKQKERETE-RDRDRQRDTEKERERQTD---------RERDRQRKTQTERQRETD-REG 225
K+KE++++ + +D++R KE+ +Q + + +++ R+ Q+ R RE D +G
Sbjct: 496 NVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQS-RSRECDITKG 554
Query: 226 ERE-TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
+ R RER R RDR + R R R +R + R KE + R+++ + R ++R+
Sbjct: 555 KHSYNSRTRERSRSRDRSR---RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRT 611
Query: 285 GEGIS 289
G S
Sbjct: 612 PPGRS 616
Score = 93.6 bits (231), Expect = 2e-19
Identities = 65/236 (27%), Positives = 117/236 (49%), Gaps = 39/236 (16%)
Query: 84 VREKTEKERDRDRK-RDRERRRKEKETNRNRDRE-------KQTEIERDREREKQKGRER 135
V E ++ ++++K +D + KE++ RN +++ K+ + R + K+K + +
Sbjct: 412 VSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSK 471
Query: 136 ERD-----------RGRERERDRDREKERERQTE-KDRDGQRETETER---------ERD 174
ERD R R + RD + KE+E+Q++ K +D +R E+ E D
Sbjct: 472 ERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHD 531
Query: 175 REREKQKERETERDRDRQRDTEK------ERERQTDRERDRQRKTQTERQRETDREGERE 228
+ K+K+R + R R+ D K R R+ R RDR R+ ++ R + DR +E
Sbjct: 532 HSKSKEKDRRAQ-SRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS-RTHDRDRSRSKE 589
Query: 229 TDRRRERQ-RDRDRGKERDRERDRKEERKKERKKERKKER-KEKKKEEKRREDKKR 282
R RE++ R R R + R+R R K+R++ R+ R E+++ + R +DK R
Sbjct: 590 YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYR 645
Score = 91.7 bits (226), Expect = 7e-19
Identities = 66/257 (25%), Positives = 118/257 (45%), Gaps = 41/257 (15%)
Query: 74 GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER-----DRERE 128
G D + +++ ++ K +D++R R +E+ ++ + + D K E +R RE +
Sbjct: 491 GRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECD 550
Query: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE-----REKQKER 183
KG+ R RER R RDR + R R DRD R E R R++E R + +ER
Sbjct: 551 ITKGKHSYNSRTRERSRSRDRSR-RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRER 609
Query: 184 ETERDRDRQRDTEKER--ERQTDRERDRQR---KTQTERQRETDREGERETDRR------ 232
T R R +D + R R ++RE + R K + + + + R+ E+++R
Sbjct: 610 RTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSR 669
Query: 233 --------RERQRDRDRG-----KERDRERDRKEERKKERKKER------KKERKEKKKE 273
RE++ DRD+ K+ ++ + K K ++ E+ K+ +K K +E
Sbjct: 670 DHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQE 729
Query: 274 EKRREDKKRKWGEGISP 290
+K +K+ SP
Sbjct: 730 NDHVHEKNKKFDHESSP 746
Score = 85.5 bits (210), Expect = 5e-17
Identities = 71/272 (26%), Positives = 121/272 (44%), Gaps = 46/272 (16%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
SR R E+P W ++E R + +R K D+ + KE
Sbjct: 349 SRDRFRRSETPPHW--------------RQEMQRAQRMRVSSGERWIKGDKSELNEIKEN 394
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD-----RDGQ 164
R+ R K+ +I R + R+ E+++ + + +E++ R +EKD + +
Sbjct: 395 QRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKK 454
Query: 165 RETETERERDREREKQKERETE---------RDRDRQRDTE--KERERQTD-------RE 206
R R + +E+ K KER+++ R R + RD E KE+E+Q+D R
Sbjct: 455 RAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERS 514
Query: 207 RDRQRKTQTE-RQRETDREGERETDRR---RERQRDRDRGK----ERDRERDRKEER-KK 257
R +++ Q E + E D +E DRR R R+ D +GK R RER R +R ++
Sbjct: 515 RSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRR 574
Query: 258 ERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
R + ++R K+ + RE + R+ G S
Sbjct: 575 VRSRTHDRDRSRSKEYHRYREQEYRRRGRSRS 606
Score = 82.0 bits (201), Expect = 6e-16
Identities = 55/198 (27%), Positives = 88/198 (44%), Gaps = 11/198 (5%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
+R R RDR R + DRDR R +E R ++ R R R R RER GR R
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRS------RSRERRTPPGRSR 617
Query: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
+DR R R RD R ERE +++D R E++ +E + ++R + RD +
Sbjct: 618 SKDR-RRRRRD-SRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRD-HNSS 674
Query: 196 EKERERQTDRERDRQRKTQTERQRETDREG--ERETDRRRERQRDRDRGKERDRERDRKE 253
RE++ DR++ K + Q + + + D + +++ K + +E D
Sbjct: 675 NNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVH 734
Query: 254 ERKKERKKERKKERKEKK 271
E+ K+ E E K
Sbjct: 735 EKNKKFDHESSPGTDEDK 752
Score = 72.4 bits (176), Expect = 4e-13
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 7/205 (3%)
Query: 84 VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER 143
+R+ K +++RK R +E ++ Q + R K KGR R R R
Sbjct: 287 MRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346
Query: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQT 203
R RDR + E ++ QR K + E ++ QR + +ER+
Sbjct: 347 SRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKI 406
Query: 204 DRERD----RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKER 259
R+ RK + E++ + + +E D RR ++D D+ K + ++R + + R K +
Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD-DKYKNKVKKRAKSKSRSKSK 465
Query: 260 KKERKKER--KEKKKEEKRREDKKR 282
+K + KER K + EEKR + +
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSK 490
Score = 72.0 bits (175), Expect = 6e-13
Identities = 55/240 (22%), Positives = 110/240 (45%), Gaps = 35/240 (14%)
Query: 76 DRQRERDRV------------REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
+R+RER+R R R K RR + +R+RDR +++E
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP 360
Query: 124 DREREKQ--------------KGRERERDRGRERERDRDREKERERQTEK------DRDG 163
+E Q KG + E + +E +R R KER+ + +R
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
++E + + + +E+ R +E+D D+ ++ K+R + R + +++ ER + +R
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKD-DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 224 EGERETDRRRERQRDRDRGKERDRERDRK-EERKKERKKERKKERKEKKKEEKRREDKKR 282
E+ R R + RD + KE++++ D K +++++ R KE+ K+ + K E + K++
Sbjct: 480 NEEKRM-RSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538
Score = 53.1 bits (126), Expect = 3e-07
Identities = 37/207 (17%), Positives = 90/207 (43%), Gaps = 7/207 (3%)
Query: 85 REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
+ K +KE + K +++ + D + ++ ++K ++R++ + R+
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK-KHRKNS 238
Query: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERET---ERDRDRQRDTEKERER 201
R +EK++ ++++K + E E + + + +E R R+ + + +
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKK 261
+ +RER+R+R+ + +R R ++ + RG R R R R + R+
Sbjct: 299 RKNRERERERECNPPNSQPASY--QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS 356
Query: 262 ERKKE-RKEKKKEEKRREDKKRKWGEG 287
E R+E ++ ++ R +W +G
Sbjct: 357 ETPPHWRQEMQRAQRMRVSSGERWIKG 383
Score = 53.1 bits (126), Expect = 3e-07
Identities = 38/183 (20%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKT-------EKERDRDRKRDRERR 103
R R ++ RS + H+ + + R+R R R RE+ K+R R R+ R
Sbjct: 576 RSRTHDRDRSRS---KEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSE 632
Query: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163
R+E + +RN+D+ + E + +E + +R + R+ + RE++ ++D+
Sbjct: 633 REESQ-SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNN---SREKKADRDQSP 688
Query: 164 -QRETETERERDREREKQKERETERDRDR-QRDTEKERERQTDRERDRQRKTQTERQRET 221
+ ++ ++ + + K +E E+ R +++ +K + ++ D ++ +K E T
Sbjct: 689 FSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGT 748
Query: 222 DRE 224
D +
Sbjct: 749 DED 751
Score = 43.1 bits (100), Expect = 3e-04
Identities = 24/133 (18%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
Query: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
I + + ++++K R + D D + + ++ D + TE + ++ +++ ++
Sbjct: 178 IPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSS-DSESATEEKSKKRKKKHRK 236
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE-RETDRRRERQRDR 239
R+ ++++ +++ ++K +++ E + T R E E R R+ + D
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 240 DRGKERDRERDRK 252
K R+RER+R+
Sbjct: 297 KERKNRERERERE 309
Score = 42.0 bits (97), Expect = 6e-04
Identities = 20/103 (19%), Positives = 54/103 (52%), Gaps = 7/103 (6%)
Query: 68 AHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER 127
+H+ + + +R + R+ R++K DR++ K ++D E ++ + +++E
Sbjct: 652 SHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKED 711
Query: 128 EKQKG---RERERDRGRERERDRDREKERERQ----TEKDRDG 163
EK + +E ++ +G+E + ++ K+ + + T++D+ G
Sbjct: 712 EKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG 754
Score = 35.0 bits (79), Expect = 0.077
Identities = 25/112 (22%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
K K ++ E+ R + + +D D Q + + + E T+ + ++++
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSS-------DSESATEEKSKKRKK 232
Query: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
K R R K+E+KK RKK +K E + E + + E I P
Sbjct: 233 ----KHRKNSRKHKKEKKK-RKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 104 bits (260), Expect = 8e-23
Identities = 66/255 (25%), Positives = 133/255 (52%), Gaps = 13/255 (5%)
Query: 42 EVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE 101
E T+ + G++ S+E + Q + ++ E D+ R + E+ R +R+R
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280
Query: 102 RRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE--RDRDREKERERQTEK 159
+ ++K+ R R + E +ERE+++ ERER R E+ +R R KE E++ +
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 160 DRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQR 219
+R +E E +R+R K++E+ +R R R E+E+ + +++R++Q + + +
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQ 400
Query: 220 ETDREGERETDR-------RRERQRDRDRG---KERDRERDRKEERKKERKKERKKE-RK 268
ET +GE+ + ++ Q D+ + K++ E+ K + K+E+ +E K +K
Sbjct: 401 ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK 460
Query: 269 EKKKEEKRREDKKRK 283
E+ K+EK ++DK+ K
Sbjct: 461 EEIKDEKIKKDKEPK 475
Score = 85.5 bits (210), Expect = 5e-17
Identities = 58/247 (23%), Positives = 120/247 (48%), Gaps = 6/247 (2%)
Query: 42 EVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRK---- 97
E T + S R E + + ++++ D D + + +EK E+E ++ ++
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204
Query: 98 RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQT 157
++ E++T +++ ++ + ++ +E ER++G + ++ +E +++
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264
Query: 158 EKDRDGQRETETERERDR-EREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTE 216
+ + E E ERER + E++K+ E R ++ +ERER+ ER+R R+ +
Sbjct: 265 AEAERARLEAE-ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR 323
Query: 217 RQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
E R E E ERQR ++ K ER R +E +K +ER++ R E++++ K
Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV 383
Query: 277 REDKKRK 283
E K+ K
Sbjct: 384 EEQKRNK 390
Score = 85.1 bits (209), Expect = 7e-17
Identities = 58/245 (23%), Positives = 115/245 (46%), Gaps = 16/245 (6%)
Query: 57 QESPRSWGLGQAHKDADGDDR----QRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
+E P+ +G+ + +++ Q E + K + + K++ ER + E + +
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 113 RDREKQTEIERDREREKQKGRERER-----------DRGRERERDRDREKERERQTEKDR 161
E++ + + ER + + ERER +R R ++ +ERER+ ++R
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
+ RE E +R+R K++E+ +R R ++ EK + R ++ +++ ERQR
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374
Query: 222 DREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
E E+ ++R + + K +E K E K E+K E K ++K +E+K +
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE-KVEQKIEGKWVNEKKAQEDKLQTAVL 433
Query: 282 RKWGE 286
+K GE
Sbjct: 434 KKQGE 438
Score = 75.9 bits (185), Expect = 4e-14
Identities = 64/261 (24%), Positives = 119/261 (45%), Gaps = 56/261 (21%)
Query: 78 QRERDRVREKTEKERD-----RDRKRDRERRRKEKETNRNRDREKQTEIERDREREK--- 129
+R + R++E E++++ D RR + +T N EK+ + E +ER +
Sbjct: 105 ERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEE 164
Query: 130 ----QKGRERERDRGRERERDRDREKERERQ-----------------TEKDRDGQRET- 167
K ++ R E + D+EKE E + EK + Q ET
Sbjct: 165 TETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETV 224
Query: 168 ------------ETERERDRER--------EKQKERETER-DRDRQRDTEKERER---QT 203
E ++E +RE+ EK +E + ER + +R R +ERER +
Sbjct: 225 VMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQ 284
Query: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263
D++ +R ++ +E ER RER R+ ++ +R+R ++EE++ +++R
Sbjct: 285 DKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQR 344
Query: 264 KKERKEKKKEEKRR--EDKKR 282
KE +++ EE++R E++KR
Sbjct: 345 IKEEEKRAAEERQRIKEEEKR 365
Score = 73.2 bits (178), Expect = 3e-13
Identities = 48/213 (22%), Positives = 107/213 (50%), Gaps = 6/213 (2%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
D + E EK+E ++R + E K + N RD E+ + ++++E E+++ +
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK 199
Query: 135 RERDRGRERE---RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
R + E ++ E + E ++GQ +E E +++ ERE+ + + ++
Sbjct: 200 RGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE-EPKQEEEREQGSDEISHHEKME 258
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
+ D E+ + E + + + + E+ ++ E R + ++R+R + +RER R
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 252 KEERKKERKKER-KKERKEKKKEEKR-REDKKR 282
+EE++ +++R K+E K +E +R +E++KR
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Score = 67.4 bits (163), Expect = 1e-11
Identities = 70/296 (23%), Positives = 134/296 (45%), Gaps = 82/296 (27%)
Query: 67 QAHKDADGDDRQR----ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIE 122
+A + A +R+R ER+R+RE+ ++ + ++ E +R +E R ++ EK+ E
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355
Query: 123 RDR--EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER------- 173
R R E EK+ ER+R R E E+ + E++R +Q E+ + +ET+ + E+
Sbjct: 356 RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEG 415
Query: 174 -----------------------------DREREKQKE------RETERDRDRQRDTEKE 198
+REK +E +E +D ++D E +
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 475
Query: 199 RERQTDRERDR---QRKTQ-----TERQRETD----REGER--------------ETDRR 232
E ++ +R + + K+Q T + + T+ R G R E +R
Sbjct: 476 EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR 535
Query: 233 RERQRDRDRGKERDRERDRKEERKKERK---KERKKERKEKKK----EEKRREDKK 281
E R R RG+ E ++ +++++E +E KK+R+E++K EE+RR+ ++
Sbjct: 536 LEELRRR-RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590
Score = 62.8 bits (151), Expect = 3e-10
Identities = 44/203 (21%), Positives = 103/203 (50%), Gaps = 7/203 (3%)
Query: 84 VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER 143
V +K +E+ + RE+ +++K T + ++ K +I++D+E +++ +R +G
Sbjct: 432 VLKKQGEEKGTKVQAKREKLQEDKPTFK-KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 490
Query: 144 ERDRDRE----KERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKER 199
+ ++ E K + + R G R + +E + + + + E R R+ +TE E
Sbjct: 491 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 550
Query: 200 -ERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKE 258
E+ ++++ + + +++ +R E + +R +Q + DR K R+ E R+ + + E
Sbjct: 551 FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR-KLREEEEKRRLKEEIE 609
Query: 259 RKKERKKERKEKKKEEKRREDKK 281
R++ E+++K E+ +DKK
Sbjct: 610 RRRAEAAEKRQKMPEDGLSDDKK 632
Score = 62.0 bits (149), Expect = 6e-10
Identities = 48/241 (19%), Positives = 114/241 (47%), Gaps = 27/241 (11%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN------------------RNRDRE 116
++RQR R EK + E + K+ E++ +ET + ++ +
Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDK 427
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
QT + + + EK + +R++ +E + +E+ ++ + +KD++ + E ++ +R +
Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKG 487
Query: 177 REKQKERETERDRDRQRDTEKERERQTDRE----RDRQRKTQTERQRETD----REGERE 228
+ K + E + + TE R R ++ + Q E + + R GE E
Sbjct: 488 FTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETE 547
Query: 229 TDR-RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
++ + +Q+ ++ E + + ++EER+K ++E ++ ++E+ + R E++KR+ E
Sbjct: 548 SEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEE 607
Query: 288 I 288
I
Sbjct: 608 I 608
Score = 59.7 bits (143), Expect = 3e-09
Identities = 41/200 (20%), Positives = 98/200 (49%), Gaps = 4/200 (2%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
DD +R R+ R+K E+ R + +R +R + E R+R ++ ER R++++++
Sbjct: 2 DDFERRRELRRQKREEMR-LEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
+ D+ ++ ++E + T + + ER RE+++++ + +RQ++
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR---ERQRDRDRGKERDRERDR 251
+ + R+ + T T++E + E+ + R E + +++ RD
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 252 KEERKKERKKERKKERKEKK 271
+E +K++++KE ++E K K+
Sbjct: 181 EENKKEDKEKEEEEEEKPKR 200
Score = 57.4 bits (137), Expect = 1e-08
Identities = 54/208 (25%), Positives = 91/208 (43%), Gaps = 30/208 (14%)
Query: 95 DRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERE 154
D +R RE RR+++E R ++ +R+ + E++ RER R +ER R + E+
Sbjct: 3 DFERRRELRRQKREEMRLE--AERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 155 RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
+ T+ Q E + E K T+ + D D ER RE RQ++ Q
Sbjct: 61 QVTD-----QVEVNAQNSVPDEEAKTTTTNTQVEGD---DEAAFLERLARREERRQKRLQ 112
Query: 215 T--ERQRETDRE-----------------GERETDRRRERQRDR-DRGKERDRERDRKEE 254
ERQ+E D E ET + E+ R +R + + E K
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 255 RKKERKKERKKERKEKKKEEKRREDKKR 282
+K + + + ++++K+KEE+ E KR
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Score = 55.8 bits (133), Expect = 4e-08
Identities = 43/208 (20%), Positives = 97/208 (46%), Gaps = 8/208 (3%)
Query: 73 DGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKG 132
+GDD +R+ + E R +KR +E ++KE + + R + + +
Sbjct: 89 EGDDEAAFLERLARREE----RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN 144
Query: 133 RERERDRGRERERDRDREKERERQTEK-DRDGQRETETERERDREREKQKERETERDRDR 191
E++ E ++R +E E T+ ++ R+ E ++ D+E+E+++E + +R
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR--ERQRDRDRGKERDRER 249
+ E E +T ++ + + + E ++E +R + + ++ +E D+ER
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264
Query: 250 DRKEERKKE-RKKERKKERKEKKKEEKR 276
E + E ++ER K ++KK ++R
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADER 292
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 6/147 (4%)
Query: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
DR + TE + + + E +R R E + + + G+ E R
Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR-- 540
Query: 142 ERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT---EKE 198
R R +E E+ +K ++ E E +++ ER K E E +R + + D E+E
Sbjct: 541 -RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 599
Query: 199 RERQTDRERDRQRKTQTERQRETDREG 225
+R+ E +R+R E++++ +G
Sbjct: 600 EKRRLKEEIERRRAEAAEKRQKMPEDG 626
Score = 28.9 bits (63), Expect = 5.5
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 12/107 (11%)
Query: 37 GTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDA-----DGDDRQRERDRVREKTEKE 91
G VE L+ R R G ES L Q ++A + ++ ER +V E+ E+
Sbjct: 526 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQR 585
Query: 92 RDRD------RKRDRERRRKEK-ETNRNRDREKQTEIERDREREKQK 131
R ++ R+ + +RR KE+ E R EK+ ++ D + +K
Sbjct: 586 RKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 104 bits (260), Expect = 8e-23
Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Query: 80 ERDRVR-EKTEKERDRDRKRDR---ERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
ERD + EKT +RD+ +++ R + +R+R R ++ + + D E K + R R
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 136 ERDRGRERERDRDREK---ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
++ R +D+ +K E E D RE E +R K+KER++ R R
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
R +ER R R R+RK R RE + R +R++ R R R+R K R R R R
Sbjct: 127 RSRSRERRH---RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-KRRIRSRSRS 182
Query: 253 EERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
R + R + R + R + ++ K+R +K R++ +S
Sbjct: 183 RSRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLS 218
Score = 104 bits (260), Expect = 8e-23
Identities = 73/252 (28%), Positives = 117/252 (46%), Gaps = 47/252 (18%)
Query: 70 KDADGDDRQRERDRVREKTEKER---DRDRKRDRERRRK-----EKETNRNRDREKQTEI 121
K + D+++E+ V + R R R RER+RK K +R+R +E +
Sbjct: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
Query: 122 ERDREREKQKG-----RERERDRGRER----ERDRDREKERERQTEKDRDGQRETETE-R 171
+D+ +K K +E D+GRER E DR K +ER++ + R R E R
Sbjct: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
Query: 172 ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR 231
R R RE++K R R+R + R +ER++ R R+R+R+ ++ R R R R R
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS-RSRSRSRHRHRTRSR 193
Query: 232 RRERQRDRDRGKERDRER----------------------------DRKEERKKERKKER 263
R R R RDR K ++ R R+ ER K+ +++R
Sbjct: 194 SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR 253
Query: 264 KKERKEKKKEEK 275
+KE EK+K+++
Sbjct: 254 EKEMVEKQKQQE 265
Score = 92.0 bits (227), Expect = 5e-19
Identities = 51/182 (28%), Positives = 88/182 (48%), Gaps = 8/182 (4%)
Query: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETE 168
++ RD + DR+++K++ R + R R + RER+ + D +G++
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
Query: 169 TERERDREREKQKER-----ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
R ++ R + K++ ++E D++ ++K RER E R + ER+ R
Sbjct: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
Query: 224 EGERETDR-RRERQRDRDRGKERDRERDRKE--ERKKERKKERKKERKEKKKEEKRREDK 280
R R RR R R R+R K R R R+RK+ R +ERKK R + R+ K++ R +
Sbjct: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
Query: 281 KR 282
R
Sbjct: 184 SR 185
Score = 76.6 bits (187), Expect = 2e-14
Identities = 53/173 (30%), Positives = 77/173 (44%), Gaps = 12/173 (6%)
Query: 48 DFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEK 107
D R RL S E+ + K + G R R R R + R+R + R R R RK+
Sbjct: 96 DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK- 154
Query: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
+R+R RE++ R RER K R R R R R R R R R + R R +DR
Sbjct: 155 --SRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR------ 203
Query: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
+ E+ R + R R R+T + + R +R +K Q +R++E
Sbjct: 204 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
Score = 54.7 bits (130), Expect = 9e-08
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Query: 174 DREREKQKERETERDRDRQRDTEKER--ERQTDRERDRQRKTQTERQRETDREGERETDR 231
D ER+ +T DRD++++ + R + R R ER+R++D EG + R
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 232 RRERQRDRDRGKERDRERDRKEERK-KERKKERKKER-KEKKKEEKRREDKKRKWGEGIS 289
R ++ R K++ ++ + EE KE ++ +ER + E R + K+RK G S
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 103 bits (258), Expect = 1e-22
Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 10/235 (4%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRR---KEK 107
R GS + G Q+ ++QR+ R R K RDR R R + R + +
Sbjct: 375 RDHRGSSSPRKESGRSQS----GSPNKQRDHSRSRSPN-KARDRSRSRSPYKARDRSRSR 429
Query: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
N+ RD + + R+R + + + RD R R ++ R++ R R K+RD +
Sbjct: 430 SPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489
Query: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER 227
+ERD R + +E + + R E++ R ++RQR+ +E DR R
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 228 ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
RE ++ R KERDR R R +++ER++ R E++ + R K+
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSS--SEERDHSRSRSPNKQ 602
Score = 101 bits (251), Expect = 9e-22
Identities = 70/266 (26%), Positives = 115/266 (43%), Gaps = 36/266 (13%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDR--------------- 94
S+G+ SQ R+ G++H + ++R R + KERD
Sbjct: 336 SKGK--SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS-KERDHRGSSSPRKESGRSQS 392
Query: 95 ---DRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
+++RD R R + R+R R + RDR R + + R+ R R + RDR +
Sbjct: 393 GSPNKQRDHSRSRSPNKA-RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451
Query: 152 ERERQTEKDRDGQRETETERERDREREKQKERE--------TERDRDRQRDTEKERE--- 200
R +D R R+R R R KER+ ERD R R KER+
Sbjct: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
Query: 201 -RQTDRERD--RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
R + +ERD R R ERQR R +E DR + R +R + R ++ +R++
Sbjct: 512 SRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
Query: 258 ERKKERKKERKEKKKEEKRREDKKRK 283
R +++ER++ + + R+ + +
Sbjct: 572 WRSPSKERERRQSRSSSEERDHSRSR 597
Score = 94.7 bits (234), Expect = 8e-20
Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 10/241 (4%)
Query: 48 DFSRGRLGSQESPRSWGLG--QAHKDADGDDRQRERDRVREKTE-KERDRDRKRDRERRR 104
D SR R ++ RS +A + + RD R ++ K RDR R R + R
Sbjct: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
Query: 105 ---KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR 161
+ + N+ RDR + ++R+ + +ERD R R ++R+ + R + K+R
Sbjct: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
Query: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKE--RERQTDRERDRQ--RKTQTER 217
D +R +ER R + + +E +R + R E+E + R +ERDR+ R ER
Sbjct: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
Query: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
+R R E D R R ++ G R R +++ + R ++ + + K
Sbjct: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
Query: 278 E 278
+
Sbjct: 640 D 640
Score = 89.7 bits (221), Expect = 3e-18
Identities = 60/248 (24%), Positives = 104/248 (41%), Gaps = 19/248 (7%)
Query: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
++G RS G++ + R R + R + KER R + R + ++
Sbjct: 325 QMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS-KERSHSHSRSSSKERDHRGSSSP 383
Query: 113 RDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
R E R + ++R+ R R + RDR + R +DR R R+
Sbjct: 384 RK-------ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Query: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE--RETD 230
R R K R+ R R + + R R ++ RDR R ++R+ + G +E D
Sbjct: 437 CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496
Query: 231 RRRERQRDRDR--------GKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
RR R ++R KERD R R ++++R++ R KE+ + + R ++R
Sbjct: 497 HRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR-SPNKERDRSQSRSPSEER 555
Query: 283 KWGEGISP 290
+ + SP
Sbjct: 556 EHRQSRSP 563
Score = 87.0 bits (214), Expect = 2e-17
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 6/239 (2%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKT-EKERDRDRKRDRERRR---K 105
SR +++ RS +A + + RDR R ++ K RD R R + R +
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 106 EKETNRNRDREK--QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163
+ ++ RD + ERD R + +ER+ + R ++RD + R E+ R
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
Query: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
R ER+R + R +ERE + R ++ ++ R R +ER+R++ + +R+ R
Sbjct: 536 SRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSR 595
Query: 224 EGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
R R + K R R +E + + KE + R D KR
Sbjct: 596 SRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
Score = 80.1 bits (196), Expect = 2e-15
Identities = 52/246 (21%), Positives = 99/246 (40%), Gaps = 16/246 (6%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTE-----KERDRDRKRDRERRR- 104
R R S R ++ A R R ++ R+ + K RDR R R + R
Sbjct: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
Query: 105 --------KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE--KERE 154
KE++ R+R K+ + + R K++ R R +ER+R + R KER+
Sbjct: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
Query: 155 RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
R + +RE R +ER++++ R ++R+R++ ER R R +++
Sbjct: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
Query: 215 TERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEE 274
R R + +E R ++ + + + +E D + ++ + +
Sbjct: 605 YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQ 664
Query: 275 KRREDK 280
R K
Sbjct: 665 NRTPSK 670
Score = 57.8 bits (138), Expect = 1e-08
Identities = 53/237 (22%), Positives = 83/237 (35%), Gaps = 50/237 (21%)
Query: 94 RDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERD--------------- 138
R R + + R + + + + + R ++ R R R
Sbjct: 275 RSRPQSHSQSRSPRRSRSGSQKRTHSRV-RSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333
Query: 139 ---------------RGRERERDRDREKER----ERQTEKDRD--GQRETETERERDRER 177
RGR R+ KER R + K+RD G E R +
Sbjct: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
Query: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237
K+R+ R R + ++ R R + RDR R + R+ R R + R+R R
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSR--SRSPYKARDRSR 451
Query: 238 DRDRGKERDRERDRKEERKKERKKER--KKER---------KEKKKEEKRREDKKRK 283
R K RD R R + ++R + R KER KE+ R K+R+
Sbjct: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
Score = 53.1 bits (126), Expect = 3e-07
Identities = 38/181 (20%), Positives = 63/181 (34%), Gaps = 6/181 (3%)
Query: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD 160
E + K N+ R + + R + + ++R R R R R R +
Sbjct: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARS--RT 318
Query: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
R G + R K K + R R R R +R R + ER
Sbjct: 319 RKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR 378
Query: 221 TDREGERETDRRRE----RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
+E+ R + +QRD R + ++ RDR R + ++R + R K +
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 277 R 277
R
Sbjct: 439 R 439
Score = 52.4 bits (124), Expect = 5e-07
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 15/187 (8%)
Query: 33 HSSLGTLWVEVTIPLDFSRGRLGSQE----SPRSWGLGQAHKDADGDDRQRERDRVREKT 88
HS LG+ E D R R S+E RS + H+ + ++R+R + R
Sbjct: 485 HSQLGSPSKE----RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
Query: 89 EKERDRDRKRDRERRRKEKETN-----RNRDREKQTEIERDREREKQKGRERERDRGRER 143
KERDR + R R+ +++ R+R R + ER+R + + ER+ R R
Sbjct: 541 -KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
Query: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR-DRQRDTEKERERQ 202
+ + R EK R E + R KE + + R D ++ R
Sbjct: 600 NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRT 659
Query: 203 TDRERDR 209
+ ++R
Sbjct: 660 SSLSQNR 666
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/172 (20%), Positives = 62/172 (36%), Gaps = 9/172 (5%)
Query: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
R++ + R + + R R + + R + R G ++ R R R +
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQK----RTHSRVRSHSWK 308
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR---RERQRDR 239
R R R R R + + + R K +++ Q T R G R +ER
Sbjct: 309 RNHSRARSRTRKGILSQMGRHSQSRSHS-KGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
Query: 240 DRGKERDRE-RDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
R ++R+ R RK+ + + K++ R +K R SP
Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 103 bits (258), Expect = 1e-22
Identities = 63/215 (29%), Positives = 128/215 (59%), Gaps = 15/215 (6%)
Query: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK-----QKGRE 134
+ +++RE EK ++++ R++E +R+E+E R +++ ++ E + R+ EK +K RE
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE-----REKQKERETERDR 189
+E+ R+ E+ ++EK RE E+ R Q E + E+ RE R+K+K E E+ R
Sbjct: 435 QEKKMWRQEEKIHEQEKIRE---EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 190 DRQRDTEKERERQTDRERD-RQRKTQTERQRETDREGERETDRRRERQRDRDR-GKERDR 247
++ ++ E+ D+E R+++ + RQ E RE E + + E+ R+++ +E++
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
+ +EE+ +E++K R++E K +++EEK RE K++
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
Score = 95.9 bits (237), Expect = 4e-20
Identities = 69/269 (25%), Positives = 145/269 (53%), Gaps = 12/269 (4%)
Query: 29 APHLHSSLGTLWVEVTIPLDFSR--GRLGSQESPRSWGLGQAHKDADGDDR-QRERDRVR 85
A HL L ++ ++ ++ + RL Q+ + W Q K + +++ Q + +++R
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIR 324
Query: 86 EKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
E+ EK R+++ K R +E EKE R E E E R ++ E+E E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ-RDTEKERERQT 203
+ ++EK RE Q EK ++ ++ E E+ +++E + ++ E R+++ + R+ EK+ RQ
Sbjct: 385 KMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263
++ ++++ + E+++E + +E R + + R + K ++E+ RK+E K R++E+
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 264 KKERKEKKKEEK----RREDKKRKWGEGI 288
+++EK +E++ R+E+K R+ E I
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Score = 95.9 bits (237), Expect = 4e-20
Identities = 59/231 (25%), Positives = 131/231 (56%), Gaps = 15/231 (6%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKE-------RDRDRKRDRERRRKEKETNRNRDREKQT 119
+ K + +++++E +++RE+ +++ R ++ R++E + +E+E R EK
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 120 EIERDREREKQKGRE---RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
E E+ RE EK++ +E R+ ++ RE+E + R+KE+ + EK R + + + E+ +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 177 REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
+E +K RE E RQ + +E+E + + ++ R+ + Q + ++ GE+E + + +
Sbjct: 507 QE-EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 237 RDRDRGKERDRERDRKEERKKERKKERK---KERKEKKKEEKRREDKKRKW 284
R K R++E +E+++K R++E K +E K +++EE +E +++ W
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Score = 95.9 bits (237), Expect = 4e-20
Identities = 57/230 (24%), Positives = 125/230 (54%), Gaps = 21/230 (9%)
Query: 79 RERDRVREKTEKERDRDRK--RDRERRRKEKETNRNRDREKQTEIERDRE---------R 127
R+ +++RE+ EK R++++K R E+ ++++ R++Q E+ R E R
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER 187
+K+K E+E+ R +E + R EK + Q EK R+ + + + E+ RE+E++ + E+
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHD-QEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 188 DRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
R+++ +++ E+ ++E Q + + RQ E RE E + ++E+ R+++
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 248 ERDRKEERKKERKKERKKERKEK---------KKEEKRREDKKRKWGEGI 288
E+ R++E + ++E+ E++EK ++EEK R +++ W + +
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Score = 89.0 bits (219), Expect = 5e-18
Identities = 56/220 (25%), Positives = 127/220 (57%), Gaps = 11/220 (5%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+++ E++++RE+ +++ + R E+ R+++E R + EK E E+ R++E++ R+
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK--EKMHEQEKIRKQEEKVWRQ 500
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK----QKERETERDRD 190
E+ +E E+ R++E++ RQ EK R+ + + + E+ RE+E+ Q+E+ E++
Sbjct: 501 EEKMHDQE-EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD 250
Q + R+ + RE++ + + Q E+ RE + + + ++ RE++ +E+ E++
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 251 RK--EERKKERKKERKKERKEKK--KEEKRREDKKRKWGE 286
K E+ +K +++E K R+E+K ++E R ++ K E
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 86.7 bits (213), Expect = 2e-17
Identities = 50/213 (23%), Positives = 122/213 (57%), Gaps = 7/213 (3%)
Query: 76 DRQRERDRVREKTEKERDRDRKRDRER--RRKEKETNRNRDREKQTEIERDRER---EKQ 130
++ RE ++ +E+ E R ++ R++E R+KEK + + R+++ ++ R E+ +++
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
Query: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190
K RE+E R+ E+ R++E++ Q EK R+ + + + E+ E+E++ + + + R
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD 250
++ E+E + + +E+ R+++ + Q E RE E + E+ +++ E+
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 251 RKEERKKERKKER--KKERKEKKKEEKRREDKK 281
+++E K R++E+ ++E + +++EEK +E ++
Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 86.3 bits (212), Expect = 3e-17
Identities = 45/213 (21%), Positives = 119/213 (55%), Gaps = 9/213 (4%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
+ K + ++ R+ +++RE+ E R +++ ++E+ RK++E ++ + + E+ RE
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 127 REKQKGRERERDRGRER----ERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
+E++ R+ E+ R +E + ++ RE+E Q ++++ G++E + + + R+++K
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
RE E Q++ +E+E + + ++ R+ + Q + ++ E+E E+ +++
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-----EKMCEQEEK 628
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEK 275
+ E+ R++E K ++ R ++++EK +E +
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 80.9 bits (198), Expect = 1e-15
Identities = 58/226 (25%), Positives = 125/226 (55%), Gaps = 11/226 (4%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L Q A+ D +E V K + + + + +R +++E++ R EK E E
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEK 315
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
+ +++K RE+E + RE++ ++ E EK+ +R+ E E++ + + +E
Sbjct: 316 IQEQEEKIREQEE---KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
E++ + EK E++ RE++ +R+ + E+ RE ++ E+E R+ ++ R++ +E
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKIREQ-EE 430
Query: 245 RDRERDRKEERKKERKKERKKERKEKKKEEK----RREDKKRKWGE 286
+ RE+++K R++E+ E++K R+E+K++E+ R+E+K R+ E
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Score = 50.8 bits (120), Expect = 1e-06
Identities = 27/119 (22%), Positives = 65/119 (54%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
Q + +++ E+ EK +++++ R +E + +E+E +EK E E +++K RE+E
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196
+ E+ ++E++ Q EK ++ + + + E+ E+E + ++ E+ ++ Q E
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 48.1 bits (113), Expect = 9e-06
Identities = 52/224 (23%), Positives = 101/224 (45%), Gaps = 25/224 (11%)
Query: 77 RQRERDRVREKTEKERDR---DRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
++++ DR E+ KERD + R+ + KE N + Q E EK + +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV-----ESEKSEIQ 241
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK-----ERETERD 188
++ R+ ER + +++ Q E D G+ + + E+ + ++ E
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
RQ + +E E + + ++ R+ Q E+ RE + + R+ + E++ R +E E
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 249 RDRKEERKKER--KKERKKERKEKK---------KEEKRREDKK 281
++ K R +E +KE K E+K +EEKR+E++K
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/117 (24%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDR 125
Q K + + +R+ +++RE+ EK R++ K R++E + E+E EK E E
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE-------EKIREQEEMM 608
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
+ +++K E+E + E+ +++E++ RQ EK + + + E+ +E ++ E
Sbjct: 609 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/159 (21%), Positives = 72/159 (45%), Gaps = 23/159 (14%)
Query: 149 REKERERQTE---KDRDG-----QRETETERERDREREKQKERETERDRDRQRDTEKERE 200
++K+ +R E K+RD R T T+ E + K +E+ + ++ +E
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 201 RQTDRERDRQRKTQTERQRETDREG---------------ERETDRRRERQRDRDRGKER 245
+ ER + Q + Q E D G E E R +Q++ ++
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
Query: 246 DRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
++ ++ +E+ +++ +K R++E K +++EEK R ++ W
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 103 bits (257), Expect = 2e-22
Identities = 66/244 (27%), Positives = 141/244 (57%), Gaps = 18/244 (7%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERR-RKEKETNRNRDR 115
+E + W Q K + Q + + R++ EK ++ +R R+RE++ R+E+ET R ++
Sbjct: 414 REQEKMWE--QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 116 EKQTEIERDREREKQKGRER----ERDRGRERERDRDREKERERQTEKDRD-----GQRE 166
+ Q + E E+E+++ +++ ++++ E+E+ +++E++ Q EK RD GQ +
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 531
Query: 167 TETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT--QTERQRETDRE 224
+E+ RE+E Q + E+ RD+++ + ER + +++++KT Q E+ RE +R
Sbjct: 532 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Query: 225 GERETDRRRERQ--RDRDRGKERDRERDRKEERKKERKKERKKERKEK--KKEEKRREDK 280
ERE R E + R+++ + E+ +++E K ++E+ +E++EK ++EEK E +
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
Query: 281 KRKW 284
++ W
Sbjct: 652 EKMW 655
Score = 102 bits (255), Expect = 3e-22
Identities = 72/254 (28%), Positives = 144/254 (56%), Gaps = 36/254 (14%)
Query: 67 QAHKDADGDDRQRERD-RVREKTEKERDRDR-----KRDRERRRKEKETNRNRDRE-KQT 119
Q K D ++R E+D R+REK E+ R++++ ++ RE ++ +++ + RD+E K
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 120 EIERDREREKQKGRERERDRGRERERDRDRE---KERERQTEKDR-DGQRETETERERDR 175
E ER REREK+ E E R +E + + E ++ E++ ++ R Q+E E+E+ +
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 176 EREKQKERETERDRDRQ---------------RDTEKERERQTDRERDRQRKT--QTERQ 218
E+E++ + E+ RD++ R+ E + Q ++ RD+++K Q ER
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 219 RETDREGERETDRRRERQRDRDRGKERDR------ERDRKEERKKERKKERKKERKEK-- 270
+ +E E++T + E+ R+ +R +ER++ E R++E K + ++E+ +E++EK
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Query: 271 KKEEKRREDKKRKW 284
++EEK +E +++ W
Sbjct: 628 EQEEKMQEQEEKMW 641
Score = 100 bits (250), Expect = 1e-21
Identities = 62/243 (25%), Positives = 133/243 (54%), Gaps = 29/243 (11%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
GQ K + + + D++ E+ EK RD+++K + R EK+T +++EK+T + ++
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT---QEQEKKTWDQEEK 584
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE------- 178
RE+++ RERE+ E E R++E++ + Q EK ++ + + + E+ +E+E
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 179 -----------------KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
+QKE+ E ++ ++++ +E+E + + ++KTQ + ++
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 222 DREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
D+E RE + RER++ +E RE++ K + ++E+ +E+++E E +EEK E ++
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE--QEEKMWEQEE 762
Query: 282 RKW 284
+ W
Sbjct: 763 KMW 765
Score = 100 bits (248), Expect = 2e-21
Identities = 62/232 (26%), Positives = 133/232 (57%), Gaps = 21/232 (9%)
Query: 75 DDRQRERD-RVREKTEK---ERDRDRKRDRERRRKEKETNRNRD-REKQTEIERDRER-- 127
++R RE++ ++RE+ EK + R R++++E R +EKE ++ RE++ +++ E+
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 128 -EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK------- 179
+++K RE+E R+ ER ++EK+ Q +K RD + + ER RE+E+
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 180 -----QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
+K RE ++ +++++ T + E+ + ER R+R+ + + ET RE E + ++ E
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 235 RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+++ + + + ++E+ E++K +++E K ++EEK R D++ WG+
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR-DQEEMWGQ 529
Score = 97.1 bits (240), Expect = 2e-20
Identities = 66/237 (27%), Positives = 131/237 (55%), Gaps = 21/237 (8%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD-R 115
++ + W + ++ +G R++E EK ++ R R++++E R +EKE ++ R
Sbjct: 290 KQEEKMWRQEERLREQEGKMREQE-----EKMWRQEKRLREQEKELREQEKELREQKELR 344
Query: 116 EKQTEIERDRER---EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
E++ +++ E+ +++K RE+E R+ ER ++EK+ Q +K RD + + E
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 173 RDREREKQ-KERETERDRDRQRDTEKERERQTDRERDRQRKTQTE---RQRETDREGERE 228
R RE+E++ +E+E ++ + EK+ + Q + RD++ K Q E R+RE E E
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 229 TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK-KEEKRREDKKRKW 284
T R +E K + +E + E+ +KE +++R E+KEK ++EK +E +++ W
Sbjct: 465 TMREQEE-------KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Score = 96.7 bits (239), Expect = 2e-20
Identities = 61/232 (26%), Positives = 121/232 (52%), Gaps = 17/232 (7%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L Q + ++ R+ + +RE+ +K R ++ K R+ R ++ + R++E++ +
Sbjct: 262 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEK 321
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEK---DRDGQRETETERERDREREKQK 181
R RE++K + RE++ R++E++ + Q EK + RE E + R ER ++
Sbjct: 322 RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
E++ + RD E+ Q +R R+++ ER RE ++ E+ R E++
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKE-----ERMREQEKMWEQVEKMREEKKMQEQE 436
Query: 242 GKERDRERD-RKEERKKERKKE--------RKKERKEKKKEEKRREDKKRKW 284
K RD+E ++EER +ER+K+ R++E K +K+EE E ++++W
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Score = 95.5 bits (236), Expect = 5e-20
Identities = 59/235 (25%), Positives = 132/235 (56%), Gaps = 15/235 (6%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDR 125
Q K D +++ +E +R+RE+ +K R+ + R++E + +++E N EK+ + +R
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 126 ER-----EKQKGRERERDRGRERERDRDRE------KERERQTE-KDRDGQRETETERER 173
E+ E++K +E+E + E+ RD+E K+ RQ + ++++ Q + E+ R
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 174 DREREK--QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR 231
D+E++ Q+ER ++ +++++ T + E+ + ER R+R+ + + E RE E +
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+ E+ ++++ E+ +++E K ++E+ E++EK E++R ++K K E
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Score = 94.0 bits (232), Expect = 1e-19
Identities = 51/222 (22%), Positives = 123/222 (55%), Gaps = 9/222 (4%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDR 125
Q K D +++ RE +R+RE+ +K R+ + R++E + +E+E EK E E
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 126 EREKQKGRERERDRGRERERDRDREK---ERERQTEKDRDGQRETETERERDREREKQKE 182
+ +++K E+E + E+ ++++ ++E+ E ++ ++E E+E +++ E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
++T+ + D EK RE ++ RER+++ + + E RE + + + + ++ +E++ +
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM--- 750
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
++E E+ +K +++R E+KEK E ++ +++++ W
Sbjct: 751 --WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Score = 90.1 bits (222), Expect = 2e-18
Identities = 68/276 (24%), Positives = 142/276 (51%), Gaps = 42/276 (15%)
Query: 52 GRLGSQESPRSWGLGQAHKDADGDDRQRERD-----RVREKTEKERDRDRKR-DRERRRK 105
G++ QE + W + ++ + + R++E++ +RE+ E+ ++++ K ++E + +
Sbjct: 307 GKMREQEE-KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 106 EKETNRNRDREKQTEIERDREREKQKGRERE-------------RDRGRERER-----DR 147
E+E R E+ E E+ ++QK R++E +R RE+E+ ++
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425
Query: 148 DREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERE---RQTD 204
RE+++ ++ EK Q E E ER REREK+ E E R+++ +K+ E Q +
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 205 RERDRQRKTQTER---QRETDREGERETDRRRERQRDRD-----------RGKERDRERD 250
+E +QR + + ++E +E E + + E+ RD++ + K R++E
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 545
Query: 251 RKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
E+ +K R +E+K +E++ E+K +E +K+ W +
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Score = 84.7 bits (208), Expect = 8e-17
Identities = 56/210 (26%), Positives = 124/210 (59%), Gaps = 13/210 (6%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
Q + + ++E+ ++ + R+++++ R++E++ R +R ++ E + RE+E++ R+ +R
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE-GKMREQEEKMWRQEKR 322
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK 197
R +E+E RE+E+E + +K+ Q E E+E +++K RE E RQ +
Sbjct: 323 LREQEKEL---REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
E+E+Q RE++++ + Q ER E D + +R RE+++ + + ++ E KK
Sbjct: 380 EQEKQM-REQEQKMRDQEERMWEQDERLREKEERMREQEKMWE-------QVEKMREEKK 431
Query: 258 ERKKERK-KERKEKKKEEKRREDKKRKWGE 286
+++E+K ++++EK +EE+R ++++K E
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Score = 81.6 bits (200), Expect = 7e-16
Identities = 49/208 (23%), Positives = 120/208 (57%), Gaps = 10/208 (4%)
Query: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDR 139
+ ++++E+ EK +++ K + + ++ +EK E E+ +E+EK + +E ++
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE---EK 685
Query: 140 GRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKER 199
E+E+ + +E+E++T D++ RE E+ RER+++ +++E E++ Q EK +
Sbjct: 686 IWEQEKMEKKTQEQEKKT-WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 200 ERQTDR-ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKE 258
E++ + E++ + Q E+ E R E ++E+ + ++ +E+++ +++E+ + +
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWEQQRLPE-----QKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 259 RKKERKKERKEKKKEEKRREDKKRKWGE 286
+K R +E K + +EEK R +++ WG+
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827
Score = 80.9 bits (198), Expect = 1e-15
Identities = 62/214 (28%), Positives = 120/214 (56%), Gaps = 18/214 (8%)
Query: 86 EKTEKERD-RDRKRDRERRR---KEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
EK+E + + ++ KR ER + + +TN ++ + E E RE+EK K R++E R
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE-EELREQEK-KIRKQEEKMWR 297
Query: 142 ERERDRDREKERERQTEKDRDGQRETETERERDRE-REKQKERETERDRDRQRDTEKERE 200
+ ER R++E + Q EK R+ + RE+++E RE++KE +++ Q + +E+E
Sbjct: 298 QEERLREQEGKMREQEEKM---WRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Query: 201 RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK---ERDRERDRKEERKK 257
+ + ++ R+ + + R+ +R E+E R + Q+ RD+ + E+D KEER +
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 258 ERKK-----ERKKERKEKKKEEKRREDKKRKWGE 286
E++K E+ +E K+ +++EK+ D++ K E
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448
Score = 80.5 bits (197), Expect = 2e-15
Identities = 57/220 (25%), Positives = 130/220 (59%), Gaps = 13/220 (5%)
Query: 75 DDRQRERDRVREK---TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
++ +++ ++EK E E+ + +E +RK + + + ++ + R++++
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 132 GRERERDRGRERERDRDREKERERQTE-KDRDGQRETETERERDREREKQ-KERETE-RD 188
RE+E+ + R++E R++ER R+ E K R+ + + + +R RE+EK+ +E+E E R+
Sbjct: 281 LREQEK-KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 189 RDRQRDTEKERERQTDR---ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
+ R+ E++ + Q ++ + ++ R+ + + R+ +R E+E R + Q+ RD+ +ER
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ-EER 398
Query: 246 DRERDRKEERKKERKKERKK--ERKEKKKEEKRREDKKRK 283
E+D + K+ER +E++K E+ EK +EEK+ +++++K
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Score = 80.1 bits (196), Expect = 2e-15
Identities = 47/217 (21%), Positives = 117/217 (53%), Gaps = 6/217 (2%)
Query: 76 DRQRERDRVREKTEK--ERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
++ +E+++++E+ EK E+++ K+ +E+ +K + + R+ E E E+ E++ R
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E+E + E+ +++E+E Q EK + + + ++ ++EK E E +++++
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 194 DTEKERERQTDRERDRQRKTQTERQRETDRE----GERETDRRRERQRDRDRGKERDRER 249
+ E++ Q ++ R ++ K + + ++ +E G+ E +E + K +E
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 250 DRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+E+ + + +K R++E K + +EEK RE +++ G+
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Score = 79.7 bits (195), Expect = 3e-15
Identities = 54/232 (23%), Positives = 125/232 (53%), Gaps = 13/232 (5%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET--------NRNRDREKQ 118
Q K + +++ E+ R+ E+ EK + ++ +++E+ ++++E + +++EK+
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 119 TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
T ++++ RE++ RERE+ E E R++E++ + Q EK ++ + E + E+ E+E
Sbjct: 703 TW-DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 179 KQ--KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQR--ETDREGERETDRRRE 234
++ +++ +++ + EK +E++ E++ + + Q E+ R E G+ E R +E
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 235 RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+ K +E + +K +E K E K + +EEK RE +++ G+
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Score = 71.2 bits (173), Expect = 1e-12
Identities = 48/220 (21%), Positives = 112/220 (50%), Gaps = 18/220 (8%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+ + +E+++ EK R+ + R+RE++ +E+E EK E E + ++++ E
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
+E + E+ ++++ E Q+E E E+ +E+EK E+E ++ RD
Sbjct: 753 QEEKMWEQEEKMWEQQRLPE---------QKEKLWEHEKMQEQEKIWEQE-----EKMRD 798
Query: 195 TEKERERQTDRERDRQRKTQTERQRETDRE----GERETDRRRERQRDRDRGKERDRERD 250
E++ Q ++ R ++ K + + ++ +E G+ E +E + K ++ +
Sbjct: 799 QEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQG 858
Query: 251 RKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
++E+ +++ +K R +E K +++EEK R +++ + G P
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGSPP 898
Score = 58.5 bits (140), Expect = 7e-09
Identities = 54/218 (24%), Positives = 113/218 (51%), Gaps = 18/218 (8%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
R ++ DR E+ KERD + R E + ++ E Q ++ E EK + +
Sbjct: 191 RHKKADRYIEELTKERDA-LSLELYRNTITNEELKKKNAELQEKLPL-AESEKSEIQLNV 248
Query: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196
++ R+ ER + + + T ++ ++E E RE++++ KQ+E+ R +R R+ E
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL-REQEKKIRKQEEKMW-RQEERLREQE 306
Query: 197 KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256
+ R+ + + RQ K E+++E RE E+E ++E + ++ +E++ + +EE
Sbjct: 307 GKM-REQEEKMWRQEKRLREQEKEL-REQEKELREQKELREQEEQMQEQEEKMWEQEE-- 362
Query: 257 KERKKERK----------KERKEKKKEEKRREDKKRKW 284
K R++E K +E++ +++E+K R+ ++R W
Sbjct: 363 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/159 (18%), Positives = 82/159 (51%), Gaps = 6/159 (3%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Q K + +++ +E++ + E++ ++ E++R ++ + + EK E E+ E
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 127 REKQKGRERERDRGRE------RERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
+E++ + E+ RG+E E+ R +E++ Q EK + + + E+ +E++
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQR 219
E + + ++ R+ E++ Q ++ R+++ K + + ++
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/155 (25%), Positives = 76/155 (49%), Gaps = 20/155 (12%)
Query: 149 REKERERQTE---KDRDG-----QRETETERERDREREKQKERE--TERDRDRQRDTEKE 198
R K+ +R E K+RD R T T E ++ + +E+ E ++ + KE
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 199 RERQTDRERDRQRKTQTE-------RQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
+R+ +R + + QT RQ E RE E++ ++ E+ R +ER RE++
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW---RQEERLREQEG 307
Query: 252 KEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
K ++E+ ++K +E++KE + +E + R+ E
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 103 bits (257), Expect = 2e-22
Identities = 58/221 (26%), Positives = 134/221 (60%), Gaps = 5/221 (2%)
Query: 67 QAHKDADGDDRQRERD-RVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
Q K D ++R E+D R+REK +ER R++K+ ++ K +E + +++EK+T + ++
Sbjct: 498 QEQKMWDQEERMWEQDERLREK--EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
RE+++ RERE+ E E R++E++ + Q EK R+ + + + E+ +E+E++ +
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
E+ +++ + + + + + E++ + + Q E+ E + E RE + + Q ++ +G+E
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQGQE- 673
Query: 246 DRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
++ R+++E+ + + +K R++E K + +EEK +++ WG+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Score = 100 bits (248), Expect = 2e-21
Identities = 70/247 (28%), Positives = 142/247 (57%), Gaps = 25/247 (10%)
Query: 58 ESPRSWGLGQAHKDADGDDRQRERDRVREKTEK--ERDRDRKRDRERRRKEKETNRNRDR 115
+ R W Q + + ++R RE++++ E+ EK E +R R+R+++ R+E+ET R ++
Sbjct: 357 QEERMWE--QDERLREKEERMREQEKMWEQEEKMQEEERIREREKK-MREEEETMREQEE 413
Query: 116 EKQTEIERDREREKQKGRER----ERDRGRERERDRDREKERERQTEKDRD-----GQRE 166
+ Q + E E+E+++ +++ ++++ E+E+ +++E++ Q EK RD GQ +
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 167 TETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226
+E+ RE+E Q + E+ RD+++ + ER E+D + + + ER RE + +
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW--EQDERLREKEERMREQKKMWQ 531
Query: 227 RETDRRRERQRDRDRGKERDR-ERDRKEERKKERKKE--------RKKERKEKKKEEKRR 277
+E R E++ K D+ E+ R+EER +ER+K+ R++E K +++EEK R
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 278 EDKKRKW 284
E +++ W
Sbjct: 592 EQEEKMW 598
Score = 96.3 bits (238), Expect = 3e-20
Identities = 52/214 (24%), Positives = 124/214 (57%), Gaps = 7/214 (3%)
Query: 79 RERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERD 138
R+ +R+RE+ K R+++ K R+ +R ++ R++EK+ ++ ++++ +E+E
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318
Query: 139 RGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR---DRQRDT 195
+ E+ R++E++ RQ E+ + +++ + ++ R++E++ + ER R +R R+
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Query: 196 EK---ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
EK + E+ + ER R+R+ + + ET RE E + ++ E +++ + + + +
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 253 EERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
+E+ E++K +++E K ++EEK R D++ WG+
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIR-DQEEMWGQ 471
Score = 94.0 bits (232), Expect = 1e-19
Identities = 56/210 (26%), Positives = 124/210 (59%), Gaps = 8/210 (3%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
Q + + ++E+ ++ + R+++++ R++E++ R +R ++ E + RE+++ R+
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE---GKMREQEEKMRRQE 282
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK 197
R RE+E++ RE+E+E + +K Q E E+E +++K RE E RQ +
Sbjct: 283 KRLREQEKEL-REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 341
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR---DRDRGKERDRERDRKEE 254
E+E+Q RE++++ + Q ER E D + +R RE+++ ++ +E +R R+R+++
Sbjct: 342 EQEKQM-REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 255 RKKERKKERKKERKEKKKEEKRREDKKRKW 284
++E + R++E K +K+EE E ++++W
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEW 430
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/224 (24%), Positives = 129/224 (57%), Gaps = 6/224 (2%)
Query: 67 QAHKDADGDDRQRERD-RVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
Q K D ++R E+D R+REK E+ R++++ ++E + +E+E R R+REK+ E +
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE--RIREREKKMREEEET 407
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
RE+++ +++ + E+E +++ Q EK + ++ E E + + EK +++E
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Query: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG---ERETDRRRERQRDRDRG 242
++++ +++ Q D+ +++ K + + Q+ D+E E++ R + +R R++
Sbjct: 468 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
K +E +EE+K + ++++ +++EK +EE+R ++++K E
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Score = 92.4 bits (228), Expect = 4e-19
Identities = 62/210 (29%), Positives = 118/210 (56%), Gaps = 6/210 (2%)
Query: 79 RERDRVREKTEKERDRDRKR-DRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
RE+ ++RE+ E+ ++++ K ++E + +E+E R E+ E E+ ++QK R++E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK 197
+ ER R++E ER R+ EK + Q E E ER REREK+ E E R+++ +K
Sbjct: 360 RMWEQDERLREKE-ERMREQEKMWE-QEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
+ E ++E ++ + Q+E + E+E + +E + K RD+E +E+K
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 258 ER-KKERKKERKEKKKEEKRREDKKRKWGE 286
R +K R++E + ++EEK R+ +++ W +
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Score = 91.7 bits (226), Expect = 7e-19
Identities = 63/234 (26%), Positives = 128/234 (54%), Gaps = 15/234 (6%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
L Q + ++ R+ + +RE+ +K R ++ K R+ R ++ + R++E++ +
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK 283
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEK---DRDGQRETET----ERERDRER 177
R RE++K + RE+++ R++E++ + Q EK + RE E + ER E+
Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRK-----TQTERQRETDREGERETDRR 232
EKQ + ++ RD++ ++ ER ++E +R R+ Q E+ +E +R ERE R
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 233 RERQRDRDR-GKERDRERDRKEERKKERKKERKKERKEKK-KEEKRREDKKRKW 284
E + R++ K + +E + E+ +KE +++R E+KEK ++EK +E +++ W
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Score = 91.7 bits (226), Expect = 7e-19
Identities = 54/238 (22%), Positives = 127/238 (53%), Gaps = 17/238 (7%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
GQ K + + + D++ E+ EK RD+++K + R ++ R R++E++ ++
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Query: 126 EREKQKGRERERDRGRERERDRDREK--ERERQTEKDRDGQRETETERERDREREKQKER 183
++++K RE ++ + +E++ EK E ER E+++ + E E RE++ + ++Q+E+
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 184 ETERDRDRQRDTEKERER------QTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237
E++ EK +E+ Q ++ +++ + + + Q E E E + + E+
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 238 DRDRGKERDRERDRKEERKKERKKERKKERKEK---------KKEEKRREDKKRKWGE 286
+++ E+ R++E K + ++E+ +E++EK ++EEK R +++ WG+
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Score = 90.5 bits (223), Expect = 2e-18
Identities = 71/232 (30%), Positives = 127/232 (54%), Gaps = 28/232 (12%)
Query: 77 RQRER-----DRVREKTEKERDRD--------RKRDRERRRKEKETNRNRDREKQTEIER 123
RQ ER ++RE+ +K RD++ R R++E R +E+E ++ EK E ER
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE-EKMQEEER 393
Query: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
REREK K RE E + E+ + +E+ Q EK+ QR E ++E+ E+EK +E+
Sbjct: 394 IREREK-KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE-QKEKLWEQEKMQEQ 451
Query: 184 ETE--------RDRDRQRDTEKERERQTD-RERDRQRKTQTERQRETDREGERETDR--- 231
E + RD++ EK+ RQ RE++ Q Q E+ R+ +++ + +R
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
+ ER R+++ ++ ++EE+ +E KK +++E+K +EEK RE+++ +
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/227 (30%), Positives = 134/227 (59%), Gaps = 28/227 (12%)
Query: 79 RERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDREREK---QKGRE 134
R+ +R+ E+ ++ R++++K RD+E R E++ R REK+ ER RE+EK Q+ +
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQD---ERLREKE---ERMREQEKMWEQEEKM 388
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER-----DR 189
+E +R RERE+ E+E R+ E+ Q E E+E E+E Q++R E+ ++
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE---EKEWQQQRLPEQKEKLWEQ 445
Query: 190 DRQRDTEKERERQTDRERDRQRKTQTER---QRETDREGERETDRRRERQRDRDR----G 242
++ ++ E++ Q ++ RD++ E+ ++E RE E + + E+ RD+++
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 243 KERDRERDRKEERKKERKKERKK--ERKEKKKEEKR-REDKKRKWGE 286
+ER E+D + K+ER +E+KK +++EK +EEK+ +E +K+ W +
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Score = 89.7 bits (221), Expect = 3e-18
Identities = 60/244 (24%), Positives = 135/244 (55%), Gaps = 22/244 (9%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD-R 115
++ + W + ++ +G R++E EK ++ R R++++E R +EKE + R
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQE-----EKMRRQEKRLREQEKELREQEKELREQKKLR 306
Query: 116 EKQTEIERDRER---EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET----- 167
E++ +++ E+ +++K RE+E R+ ER ++EK+ Q +K RD +
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 168 --ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225
+ ER RE+EK E+E E+ ++ +R E+E++ + + E R+++ + ++Q E E
Sbjct: 367 RLREKEERMREQEKMWEQE-EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER---KEKK--KEEKRREDK 280
E + +++ +++ E+++ ++++E+ ++ +K R +E +EKK ++EK RE +
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 281 KRKW 284
+ W
Sbjct: 486 DQMW 489
Score = 89.0 bits (219), Expect = 5e-18
Identities = 52/235 (22%), Positives = 131/235 (55%), Gaps = 15/235 (6%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Q K + + Q + +++ E+ EK RD++ +E++ +E R ++ + + E+ R+
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 127 REKQKGRERER-----DRGRERERDRDREKERERQTEKDRDGQRETETERE--------R 173
+E++ + ER +R RE+E +K+ +Q EK R+ ++ E E++ R
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER-ETDRR 232
+ ER +++E++ + + R+ E++ + Q ++ R+++ K + ++ ++E + E + +
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 233 RERQRDRDRGKERDRERDRKEERKKERKKER-KKERKEKKKEEKRREDKKRKWGE 286
Q + D+ +E++ +EE+ +E++++ ++E K +++EEK RE +++ G+
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Score = 89.0 bits (219), Expect = 5e-18
Identities = 55/213 (25%), Positives = 117/213 (54%), Gaps = 6/213 (2%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+++ RE + +E+ +K D++ K E R +E+E + E E E + +++K RE
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
+E + E+ +++E++ Q EK + Q E + +E++ +Q+E+ E++
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWE-QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 195 TEKERERQTD-RERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKE 253
EK RE++ RE++ + + Q E+ RE + + + + ++ RE Q ++ RG+E E+ +
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE-QEEKMRGQE---EKMWGQ 707
Query: 254 ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
E K ++E+ ++E +++E+R D+K K E
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Score = 88.6 bits (218), Expect = 6e-18
Identities = 52/208 (25%), Positives = 106/208 (50%), Gaps = 2/208 (0%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKERDRDR-KRDRERRRKEKETNRNRDREKQTEIERDR 125
Q K D +++ RE +R+RE+ +K R+ + R++E + +E+E EK E E
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
+ +++K E+E + E D+ +E+E E E++ Q + E E++ + +Q+E+
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQE-EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
Query: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
E++ Q EK RE++ + ++ + E + E + + Q ++ G+E
Sbjct: 664 EQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 723
Query: 246 DRERDRKEERKKERKKERKKERKEKKKE 273
RE++ + +KE+ +ER E +E+ E
Sbjct: 724 MREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 87.8 bits (216), Expect = 1e-17
Identities = 57/226 (25%), Positives = 131/226 (57%), Gaps = 18/226 (7%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
++++ ++ R+ E+ EK ++++ +++E + E+E + RD+E+ E+ R+ +K RE
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQ-EKMRE 483
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK-----QKERETERDR 189
+E + E+ RD+E++ Q E+ + + ER RE++K +K RE ++ +
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 190 DRQRDT----EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
++++ T EK RE + RER+++ + + E RE + + + + ++ RE++ +E+
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 246 DRERDRK----EERKKERKKERKKERKEK---KKEEKRREDKKRKW 284
+E++ K EE+ E+++E K + +E+ ++EEK +E +++ W
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Score = 84.0 bits (206), Expect = 1e-16
Identities = 55/215 (25%), Positives = 129/215 (60%), Gaps = 10/215 (4%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRER-EKQKGRERE 136
+R+ +R + + + + + R+ +E + R+++ ++ R ER +Q+G+ RE
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 137 RDRGRERERDRDREKERE-RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
++ R+ R RE+E+E R+ EK+ RE + RE++ + ++Q+E+ E++ ++ R+
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKEL---REQKKLREQEEQMQEQEEKMWEQE-EKMREQ 329
Query: 196 EKERERQTDR--ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKE 253
E++ RQ +R E+++Q + Q ++ R+ + + +R RE++ +R R +E+ E++ K
Sbjct: 330 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKM 388
Query: 254 ERKKERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
+ ++ER +ER+K+ +E+++ + +E+K +K E +
Sbjct: 389 Q-EEERIREREKKMREEEETMREQEEKMQKQEENM 422
Score = 82.4 bits (202), Expect = 4e-16
Identities = 58/223 (26%), Positives = 132/223 (59%), Gaps = 13/223 (5%)
Query: 75 DDRQRERDRVREK---TEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQK 131
++ +++ ++EK E E+ + +E +RK + + + ++ + R++++
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 132 GRERERDRGRERERDRDREKERERQTE-KDRDGQRETETERERDREREKQ-KERETE-RD 188
RE+E+ + R++E R++ER R+ E K R+ + + + +R RE+EK+ +E+E E R+
Sbjct: 243 LREQEK-KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 189 RDRQRDTEKERERQTDR---ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245
+ + R+ E++ + Q ++ + ++ R+ + + R+ +R E+E R + Q+ RD+ +ER
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ-EER 360
Query: 246 DRERDRKEERKKERKKERKK--ERKEKKKEEKRREDKKRKWGE 286
E+D + K+ER +E++K E++EK +EE+R ++++K E
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Score = 71.2 bits (173), Expect = 1e-12
Identities = 58/241 (24%), Positives = 125/241 (51%), Gaps = 21/241 (8%)
Query: 69 HKDADG--DDRQRERDRV-----REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI 121
HK AD ++ +ERD + R E + + + + + + E+ ++ + E+
Sbjct: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
Query: 122 ERDREREK-----QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
+R ER K + + + R+ E R++EK+ +Q EK + + + RE
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 177 REKQKERETERDRDRQ---RDTEKE-RERQTDRERDRQRKTQTER---QRETDREGERET 229
+E++ R+ +R R+++ R+ EKE RE++ RE++ Q + Q E+ Q E RE E +
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 230 DRRRER--QRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
R+ ER ++++ ++ + RD++E ++ ++ R+KE + +++E+ +++K + E
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 288 I 288
I
Sbjct: 394 I 394
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 102 bits (253), Expect = 5e-22
Identities = 66/227 (29%), Positives = 116/227 (51%), Gaps = 14/227 (6%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
G+ A R +E D + E+ R DR + KE + +RDR+++ E++ DR
Sbjct: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDA-EIKERSTSRDRKQKEELKEDR 192
Query: 126 E-REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
+ REK K +E+ ++ G R R+ +RE+ + R + + ER+RD ER+K+ ER+
Sbjct: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
Query: 185 TE--RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR-------ER 235
+E ++++R RD ++ER+R ++RDR+R E + DRE RE D+ E
Sbjct: 253 SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
Query: 236 QRDRDRGKERDRERDRKEE---RKKERKKERKKERKEKKKEEKRRED 279
+ G +D + + + E R + + +R+ K E R+ED
Sbjct: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
Score = 101 bits (251), Expect = 9e-22
Identities = 63/201 (31%), Positives = 107/201 (53%), Gaps = 25/201 (12%)
Query: 88 TEKERDRDRKRDRERRRKEKETNRNRDREKQTEI-ERDREREKQKGRERERDRGRERERD 146
T + ++ D K RE +E ++N + EI ER R++++ E + DR + RE+D
Sbjct: 143 TSRSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKD 198
Query: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206
+D+EK +E + R+G+RE R R + E+QK+R +R+
Sbjct: 199 KDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-----------------ERD 240
Query: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
RD +RK +TER+ E +E ER DR +R+RDRD+GK+RDR R + E + +E+ +E
Sbjct: 241 RDSERKKETERKSEGGKEKERLRDR--DRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
Query: 267 RKEKKKEEKRREDKKRKWGEG 287
+ +K+ + +K +G
Sbjct: 299 HDKPEKKSASSGEMSKKLSDG 319
Score = 80.5 bits (197), Expect = 2e-15
Identities = 45/176 (25%), Positives = 91/176 (51%), Gaps = 6/176 (3%)
Query: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR 113
L PR + +G +R RE +R R K D +R++DR R +++++ R +
Sbjct: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
Query: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
+ E+++E +++ER + + RER+RD+G ++RDR R K E + DR+ RE + ++
Sbjct: 248 ETERKSEGGKEKERLRDRDRERDRDKG--KDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
Query: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR-EGERE 228
+ ++ ++ +D++ E E + + T+T ++R + EG +E
Sbjct: 306 SASSGEMSKKLSD---GTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
Score = 60.8 bits (146), Expect = 1e-09
Identities = 40/156 (25%), Positives = 81/156 (51%), Gaps = 13/156 (8%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
+R R G +E ++ + D +R+R+RD +E++++ +RK + KEKE
Sbjct: 210 NRHREGERERAKARARPDNERQKDRGNRERDRD-----SERKKETERKSE---GGKEKER 261
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERE----RQTEKDRDGQ- 164
R+RDRE+ + +DR+R + K E D RE+ R+ D+ +++ ++K DG
Sbjct: 262 LRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTF 321
Query: 165 RETETERERDREREKQKERETERDRDRQRDTEKERE 200
++++ E E + K T+ + R +++ + R+
Sbjct: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRK 357
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 100 bits (248), Expect = 2e-21
Identities = 61/227 (26%), Positives = 114/227 (50%), Gaps = 4/227 (1%)
Query: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
G+ A R +E D + E+ R DR + KE + +RDR+++ E++ DR
Sbjct: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDA-EIKERSTSRDRKQKEELKEDR 192
Query: 126 E-REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
+ REK K +E+ ++ G R R+ +RE+ + R + + ER+RD ER+K+ ER+
Sbjct: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
Query: 185 TE--RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
+E ++++R RD ++ER+R ++RDR+R E + DRE RE D+ ++
Sbjct: 253 SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
Query: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
++ + K+ + + + + K + +R K G+ S
Sbjct: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTS 359
Score = 99.0 bits (245), Expect = 4e-21
Identities = 61/206 (29%), Positives = 107/206 (51%), Gaps = 9/206 (4%)
Query: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
D VR E+ + R R ++ N+N E+ + +R + +ER R R
Sbjct: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
Query: 142 ERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERER 201
++++ +E + R+ +KD++ +E R R+ ERE+ K R D +RQ+D
Sbjct: 183 -KQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKAR-ARPDNERQKD-----RG 235
Query: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKK 261
+R+RD +RK +TER+ E +E ER D R+R+RDRD+GK+RDR R + E + +
Sbjct: 236 NRERDRDSERKKETERKSEGGKEKERLRD--RDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
Query: 262 ERKKERKEKKKEEKRREDKKRKWGEG 287
E+ +E + +K+ + +K +G
Sbjct: 294 EKNREHDKPEKKSASSGEMSKKLSDG 319
Score = 82.8 bits (203), Expect = 3e-16
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Query: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR 113
L PR + +G +R RE +R R K D +R++DR R +++++ R +
Sbjct: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
Query: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
+ E+++E +++ER + + RER+RD+G ++RDR R K E + DR+ RE + ++
Sbjct: 248 ETERKSEGGKEKERLRDRDRERDRDKG--KDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
Query: 174 DR---EREKQKERETERDRDRQRDTE---KERERQTDRERDRQRKTQTERQRETDREGE 226
E K+ T +D + +TE + + T + R+ K E +D EG+
Sbjct: 306 SASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 100 bits (248), Expect = 2e-21
Identities = 65/242 (26%), Positives = 123/242 (50%), Gaps = 8/242 (3%)
Query: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
SRGR GS+ RS ++ + D R R+RDR RE++ R RD++R R R RK
Sbjct: 14 SRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERS---RSRDKRRSRSRDRKRLRR 70
Query: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKE---RERQTEKDRDGQRE 166
+R+R+R++ E R R R++++ R R R R ++ K+ R R EK G+
Sbjct: 71 SRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESS 130
Query: 167 TETERERDREREKQKERETER-DRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225
E ++++D ++E +KE++ D+++ + ++R+ + ++ R+ QRK E E +E
Sbjct: 131 KEKKKDKD-DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEI 189
Query: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWG 285
E ++ D D ++ E +++ + + + E+ KEE ++ + + G
Sbjct: 190 EEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKG 249
Query: 286 EG 287
G
Sbjct: 250 GG 251
Score = 95.9 bits (237), Expect = 4e-20
Identities = 53/176 (30%), Positives = 91/176 (51%), Gaps = 3/176 (1%)
Query: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQ 164
+E R R + R R R R + D R R RDRDR +ER R +K R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 165 RETE-TERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTE-RQRETD 222
R+ + R R RER++ +ER R RDR+R + R R++ + +TE R R +
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 223 REGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
+ E+ + +++ +D D+ E++++ ++ K E + ++KER EK +EE+R++
Sbjct: 123 KTDGGESSKEKKKDKD-DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
Score = 92.0 bits (227), Expect = 5e-19
Identities = 58/200 (29%), Positives = 96/200 (48%), Gaps = 13/200 (6%)
Query: 87 KTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERD 146
K R R R R R +K + R DR R R R++ + RER R R + R R
Sbjct: 10 KRSASRGRSGSRSRSRSPSDKRSKRGDDR-------RSRSRDRDRRRERSRSRDKRRSRS 62
Query: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206
RDR++ R R ++RD RE R RDR R + + R R R + ++ +R
Sbjct: 63 RDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRSRGR---RSRSSSPGNKSKKTENRS 118
Query: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
R +++ E +E ++ + + D + + + D+ K + R RKE +K R+++RKK
Sbjct: 119 RSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKA 178
Query: 267 RKEKKKEEKRREDKK--RKW 284
+ + +K E+ K +KW
Sbjct: 179 MENIGELKKEIEEMKQGKKW 198
Score = 89.0 bits (219), Expect = 5e-18
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 12/175 (6%)
Query: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
R+R +GR R R R R + + R +DRD +RE R++ R R + ++R
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKR- 67
Query: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG--ERETDRRRERQRDRDRG 242
R R R+RD +ER R R+R R R R+ + G ++T+ R + D G
Sbjct: 68 LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGG 127
Query: 243 ---KERDRERDRKEERKK------ERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
KE+ +++D KE+ K+ ++ K ++ RK K++ EK RE++++K E I
Sbjct: 128 ESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENI 182
Score = 83.2 bits (204), Expect = 2e-16
Identities = 54/159 (33%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
GRE R R R R + R R R + + R RDR+R +++ R ++ R R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
RD ++ R R RERDR R+ + R R DRRR R R R R R R
Sbjct: 62 SRDRKRLR-RSRSRERDRSRERRRSRSR----------DRRRSRSRSRGR---RSRSSSP 107
Query: 252 KEERKKERKKERKKER-------KEKKKEEKRREDKKRK 283
+ KK + R KE+ KEKKK++ +ED+K K
Sbjct: 108 GNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK 146
Score = 60.1 bits (144), Expect = 2e-09
Identities = 40/132 (30%), Positives = 56/132 (42%), Gaps = 22/132 (16%)
Query: 171 RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETD 230
RE R++ R R R R +R ++ D R R R R+ RE R D
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSR------DRDRRRERSRSRD 56
Query: 231 RRRERQRDRDR---GKERDRERDRKEERKKERKKERKKER-------------KEKKKEE 274
+RR R RDR R + R+R+R R+ R + R + R + R K KK E
Sbjct: 57 KRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTEN 116
Query: 275 KRREDKKRKWGE 286
+ R +K GE
Sbjct: 117 RSRSKEKTDGGE 128
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 99.0 bits (245), Expect = 4e-21
Identities = 56/225 (24%), Positives = 139/225 (61%), Gaps = 11/225 (4%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+++ E++++RE+ EK ++ ++ R++E+R++++ ++ + + + E+ RE+EK+ R+
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 135 RERDRGRERERDRDREKERE---RQTEKDRDGQ---RETETERERDREREKQKE---RET 185
E+ +E+ R+ ++ +E+E RQ EK + + R+ E E++ + KQ+E R+
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER--ETDRRRERQRDRDRGK 243
E+ R+++ ++ E+ +E + + + R+ E E E+ E ++R+E++ R +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
E+ RE++ K R++E+ +E++++R+E++++ ++E+K R+ E I
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Score = 98.2 bits (243), Expect = 7e-21
Identities = 70/271 (25%), Positives = 144/271 (53%), Gaps = 18/271 (6%)
Query: 29 APHLHSSLGTLWVEVTIPLDFSR--GRLGSQESPRSWGLGQAHKDADGDDR-QRERDRVR 85
A HL L ++ ++ ++ + RL Q+ + W Q K + +++ Q + +++R
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIR 324
Query: 86 EKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
E+ EK R+++ K R +E EKE R E E E R+++ E+E R+ E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 145 RDRDREK------ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKE 198
++E+ E+ + EK R+ Q E E E+ RE+EK++E+E + R ++ E+E
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443
Query: 199 ---RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ--RDRDRGKERDRERDRKE 253
RE++ R ++ + E+ RE ++ E+E R+E + + +++++ +++E
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 254 ERKKERKKERKKERKEKKKEEKRREDKKRKW 284
+ +K+ +K ++E K +++EEK RE +++ W
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Score = 97.8 bits (242), Expect = 1e-20
Identities = 59/220 (26%), Positives = 129/220 (58%), Gaps = 15/220 (6%)
Query: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK-----QKGRE 134
+ +++RE EK ++++ R++E +R+E+E R +++ ++ E + R+ EK +K RE
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQ-RETETERERD---REREKQKERETERDRD 190
+E+ R+ E+ ++EK RE + ++++ R+ E E++ R++EK E+E + +
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGE---RETDRRRERQRDRDRGKERDR 247
++ +E + + E+ R+++ + RQ E RE E RE ++ E+++ + K +++
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 248 ERDRKEERKKERKKERKKERKEKK---KEEKRREDKKRKW 284
E + +K R++E K R+E+K +EEKR+E +++ W
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Score = 95.5 bits (236), Expect = 5e-20
Identities = 63/213 (29%), Positives = 123/213 (57%), Gaps = 11/213 (5%)
Query: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERER 137
+R+ + + EK EK R+ + K + + +E+E R ++ EK E E+ +E+E + R+ E+
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 138 DRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK 197
R +E E+ R++EK+ RQ EK + ++ E E+ +++E ++E + + R EK
Sbjct: 439 IREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
Query: 198 ERERQTDRERDRQRKTQTERQRETDREGE---RETDRRRERQRDRDRGKE---RDRERDR 251
E++ E+ R+++ + RQ E RE E RE + + RQ ++ R +E R+ E+
Sbjct: 498 MHEQE---EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 252 KEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
++E+ E +K +++E K ++EEK RE +++ W
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Score = 94.7 bits (234), Expect = 8e-20
Identities = 59/206 (28%), Positives = 118/206 (57%), Gaps = 13/206 (6%)
Query: 79 RERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERD 138
R+ +++RE+ EK R+++ K R+ + ++ R+ EK E E+ E EK++ E+E
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ--EQEDK 571
Query: 139 RGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKE 198
R+ E+ R++E++ RQ EK R+ + E +E++ + KQ+E+ E++ Q EK
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIRE---QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 199 RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKE 258
RE++ E+ R+++ T+ Q E E E + + E+ ++++ R E+ R++E
Sbjct: 629 REQE---EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE---- 681
Query: 259 RKKERKKERKEKKKEEKRREDKKRKW 284
KK R++E K +++EE +E +++ W
Sbjct: 682 -KKIREQEEKIREQEEMMQEQEEKMW 706
Score = 93.6 bits (231), Expect = 2e-19
Identities = 60/239 (25%), Positives = 137/239 (57%), Gaps = 24/239 (10%)
Query: 67 QAHKDADGDDRQRERDRVREKTEKE-------RDRDRKRDRERRRKEKETNRNRDREKQT 119
+ K + +++++E +++RE+ +++ R ++ R++E + +E+E R EK
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
Query: 120 EIERDREREKQKGRER----------ERDRGRERERDRDREKERERQTEKDRDGQRETET 169
E E+ RE EK++ +E + + R++E+ ++E++ +Q EK + +
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
Query: 170 ERERDREREKQKERETERDRDRQ---RDTEK--ERERQTDRERDRQRKTQTERQRETDRE 224
+ E+ RE+E++ R+ E+ R+++ R+ EK E+E+ + E+ ++++ + RQ E RE
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 225 GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEK--KKEEKRREDKK 281
E + R+ E+ R+++ ++ E+ K+E K ++E+ +E++EK ++EEK RE ++
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 92.0 bits (227), Expect = 5e-19
Identities = 56/218 (25%), Positives = 133/218 (61%), Gaps = 11/218 (5%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
+++ E++++RE+ +++ + R E+ +++E R +++ + E E+ R++E++ R+
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQ 515
Query: 135 RERDRGRERERDRDREKERERQTEKDRDGQ---RETETERERDREREKQKERETERDRDR 191
E+ R +E E+ R++E++ RQ EK R+ + RE E E+++ E++K +E E R
Sbjct: 516 EEKIREQE-EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD- 250
Q + +E+E + R+ ++ R+ + +RQ + ++ ++E ++ RE++ +E+ RE++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE-EKIREQEEKIQEQEEKIREQEE 633
Query: 251 --RKEERKKERKKERKKERKEK--KKEEKRREDKKRKW 284
R++E + ++E+ E++EK ++EEK +E ++ W
Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Score = 91.7 bits (226), Expect = 7e-19
Identities = 60/220 (27%), Positives = 131/220 (59%), Gaps = 14/220 (6%)
Query: 79 RERDRVREKTEKERDRDRK--RDRERRRKEKETNRNRDREKQTEIERDRER---EKQKGR 133
R+ +++RE+ EK R++++K R E+ ++++ R++Q E+ R E+ +++ R
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE---RDRD 190
++E+ +E E+ R +E++ RQ EK R+ Q E E+E R+++K RE E R+ +
Sbjct: 494 QKEKMHEQE-EKIRKQEEKVWRQEEKIRE-QEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE---RDR 247
+ + EK E + +E++ + Q E+ RE + + R+ ++ RE++ R +E +
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 248 ERDRKEERKKERKKERKKERKEK-KKEEKRREDKKRKWGE 286
E+ R++E K + ++E+ +E++EK +++E+ ++++ K GE
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Score = 90.1 bits (222), Expect = 2e-18
Identities = 54/225 (24%), Positives = 122/225 (54%), Gaps = 13/225 (5%)
Query: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR----------EKQTEIERDRE 126
RQ E+ R +E+ +E++ R E+ R+++E R ++ EK+ E E
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Query: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186
R+++K RE+E R+ E+ R++E++R+ Q EK + + + E+ +E+E++ + E
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Query: 187 RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
+ R+++ T+++ E+ ++E + + +++E + E R +E++ K R+
Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Query: 247 RERDRKEERKKERKKERK---KERKEKKKEEKRREDKKRKWGEGI 288
+E +E+ +K ++E K +E K +++EEK R +++ W + +
Sbjct: 694 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 86.7 bits (213), Expect = 2e-17
Identities = 55/212 (25%), Positives = 120/212 (56%), Gaps = 13/212 (6%)
Query: 77 RQRERDRVREKTEKERDRDRKRDR---ERRRKEKETNRNRDREKQTEIERDREREKQKGR 133
RQ E+ R +E+ +E ++ ++++ E +R+E+E R EK E E R+++K R
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
E+E E+ +++E++ +Q EK R+ + + + + E+ RE+E++ + E ++++
Sbjct: 595 EQE-------EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Query: 194 DTEKERERQTDRERDRQRKTQTE-RQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
++ E+ ++E Q + +T RQ E RE E++ + E+ R+++ + E+ +
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Query: 253 EERKKERKKERKKERKEK--KKEEKRREDKKR 282
+E K ++E+ +E++EK ++EEK E + R
Sbjct: 708 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 82.0 bits (201), Expect = 6e-16
Identities = 52/235 (22%), Positives = 123/235 (52%), Gaps = 15/235 (6%)
Query: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR-----EKQT 119
L Q A+ D +E V K + + + + +R +++E++ R ++ EK
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTE----KDRDGQRETETERERDR 175
E E +++K RE+E R+ E ++E++ RQ E K+ +R+ E E++
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 176 EREKQKERETERDR------DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERET 229
+ +Q+E E++ ++ + EK RE++ R+ + + + Q +RQ + + +E
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Query: 230 DRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
R + ++ R++ K+ R+ ++ E++K R++E+++E++E ++E++ +++ W
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Score = 77.0 bits (188), Expect = 2e-14
Identities = 52/225 (23%), Positives = 117/225 (52%), Gaps = 6/225 (2%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
++ + W + ++ + R+ E+ +EK +E R + D+ R++EK +
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
+Q E R++E EK++ E+E ++ E+ R++E++ + Q EK R+ + + + E +E
Sbjct: 588 RQEEKIREQE-EKRQ--EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 177 R-EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER 235
+ EK E+E + ++ E+E E+ R+++ + Q E RE E + E+
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704
Query: 236 QRDRDRGKERDRERDRKEERKKERKKER--KKERKEKKKEEKRRE 278
+++ E+ +++E K R++E+ ++E + +++EEK +E
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 63.5 bits (153), Expect = 2e-10
Identities = 60/269 (22%), Positives = 126/269 (46%), Gaps = 62/269 (23%)
Query: 77 RQRERDRVREKTEKERD-------RDRKRDRERRRKEK---------ETNRNRDREKQTE 120
++++ DR E+ KERD R+ D E + K E+ ++ + E
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 121 IERDREREK----QKGRERERDR-GRERER------------------DRDREKERERQT 157
++R ER K Q+ + E D G+E + ++ +E++ RQ
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
Query: 158 EKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217
EK ++ + + + + E+ RE+E +K RE E RQ + E+E + R+ + + + +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 218 QRETDREGERETDRRRERQRDRDRGK----------ERDRERDRKEERKKERKKERKKER 267
+R+ + E+E RR+ + ++ + E+++ R+++E+R++E K +++R
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 268 KE------------KKKEEKRREDKKRKW 284
+E +++EEK RE +K+ W
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMW 454
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 99.0 bits (245), Expect = 4e-21
Identities = 67/252 (26%), Positives = 128/252 (50%), Gaps = 43/252 (17%)
Query: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKE---KETNRNRDREKQTEIERDREREKQK 131
D + R+ +E+ ++ R DR+RDR+R RK K+ R+R R+++ R R R + K
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
ERER R +ERERD++R++ + + ++D+DG R + + + K+ ++ +DRD
Sbjct: 67 SAERER-RHKERERDKERDRNK-KDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDS 124
Query: 192 QRDTEKER-----------------ERQTDRERD----------RQRKTQTERQRETDRE 224
++D E E +++ + E + R+ + RQ+E +
Sbjct: 125 KKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEER 184
Query: 225 GERETDRRRERQRDRDRGK---ERDRERDRKEERKK--------ERKKERKKERKEKKKE 273
+ R++R++ +D G+ E +ER+R+E R++ E ++ R+K R+EK K
Sbjct: 185 QRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKS 244
Query: 274 EKRREDKKRKWG 285
++ K+R G
Sbjct: 245 KELHAIKERYLG 256
Score = 97.1 bits (240), Expect = 2e-20
Identities = 63/244 (25%), Positives = 123/244 (50%), Gaps = 36/244 (14%)
Query: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
KD D + ER R R +R+RDR RDR + K+ R+R R+++ R R R +
Sbjct: 9 KDRDASPSKEERKRSRTP---DRERDRDRDR-KSSPSKDRKRHRSRDRRRGGSRSRSRSR 64
Query: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
K ERER R +ERERD++R++ + + ++D+DG R + + + K+ ++ +DR
Sbjct: 65 SKSAERER-RHKERERDKERDRNK-KDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDR 122
Query: 190 DRQRDTEKER-----------------ERQTDRE----------RDRQRKTQTERQRETD 222
D ++D E E +++ + E +R+ + RQ+E +
Sbjct: 123 DSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVE 182
Query: 223 REGERETDRRRERQRDRDRGK---ERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
+ R++R++ +D G+ E +ER+R+E R++ ++ E +E +++ + +D
Sbjct: 183 ERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKD 242
Query: 280 KKRK 283
K ++
Sbjct: 243 KSKE 246
Score = 97.1 bits (240), Expect = 2e-20
Identities = 73/247 (29%), Positives = 130/247 (52%), Gaps = 43/247 (17%)
Query: 76 DRQRERDRVREKT-EKERDRDRKRDRER---RRKEKETNRNRDREKQ-TEIERDREREKQ 130
DR+R+RDR R+ + K+R R R RDR R R + + +++ +RE++ E ERD+ER++
Sbjct: 27 DRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRN 86
Query: 131 KGRERERDR-GRERERDRDRE-----KERERQTEKDRDGQRETETE-------------- 170
K ++R+RD+ G R++DR R + ++ ++ KDRD +++ E E
Sbjct: 87 K-KDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLE 145
Query: 171 -----RERDRERE------KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQR 219
++ + E E + ERE E + RQ++ E ER+R + ER ++++ Q ++
Sbjct: 146 ELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVE-ERQRMLEEERKKRKQFQDLGRK 204
Query: 220 ETDREGERETDRRRERQRDRDRGKERDRERDR-KEERKKERKKERKKERK----EKKKEE 274
+ ERE RRER G E + R + +EE+ K ++ KER +K++
Sbjct: 205 MLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRT 264
Query: 275 KRREDKK 281
+ D+K
Sbjct: 265 RHLNDRK 271
Score = 80.1 bits (196), Expect = 2e-15
Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 21/143 (14%)
Query: 154 ERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT 213
E +KDRD E +R+R + +RE +RDRDR+ K+R+R R RDR+R
Sbjct: 4 ELADKKDRDASPSKE-----ERKRSRTPDRERDRDRDRKSSPSKDRKRH--RSRDRRRGG 56
Query: 214 QTERQRETDREGERETDRRRERQRDRDRGK-ERDRERDRKEERK-KERKK---------- 261
R R + ERE R +ER+RD++R + ++DR+RD+ R+ K+RK+
Sbjct: 57 SRSRSRSRSKSAERER-RHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKD 115
Query: 262 -ERKKERKEKKKEEKRREDKKRK 283
+ +K+R KK EE DKK K
Sbjct: 116 FKSRKDRDSKKDEEDEHGDKKPK 138
Score = 79.3 bits (194), Expect = 4e-15
Identities = 55/175 (31%), Positives = 88/175 (50%), Gaps = 14/175 (8%)
Query: 122 ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
+RD K++ R+R R RER+RDRDR+ + ++ R R R R R R K
Sbjct: 10 DRDASPSKEE-RKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSA 68
Query: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
ERE R ++R+RD E++R ++ DR+RD+ + + ++ + R D + + RD +
Sbjct: 69 ERE-RRHKERERDKERDRNKK-DRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKK 126
Query: 242 GKERDRERDRK--------EERKKERKKERKKERKEK--KKEEKRREDKKRKWGE 286
+E D D+K EE ++K E + E K K K E+ E KR+ E
Sbjct: 127 DEE-DEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQE 180
Score = 79.0 bits (193), Expect = 5e-15
Identities = 49/172 (28%), Positives = 91/172 (52%), Gaps = 22/172 (12%)
Query: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK 179
E+ ++R+ +E +R R R DR+R+++R+R++ +D +R +R R R +
Sbjct: 4 ELADKKDRDASPSKE---ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSR 60
Query: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG-ERETDRRRE---- 234
+ R +R+R + +ER+ D+ERDR +K R+ D++G R+ DR+R
Sbjct: 61 SRSRSKSAERER-----RHKERERDKERDRNKK-----DRDRDKDGHRRDKDRKRSSLSP 110
Query: 235 -RQRDRDRGKERDRERDRKEERKKERKKERKKERKE---KKKEEKRREDKKR 282
R +D K+RD ++D ++E ++ K + +E KKK E+ E K +
Sbjct: 111 GRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPK 162
Score = 73.2 bits (178), Expect = 3e-13
Identities = 78/314 (24%), Positives = 140/314 (44%), Gaps = 84/314 (26%)
Query: 51 RGRLGSQESPRSWGLGQAHKDADGDDR--QRERDRVREKTEKERDRDR---KRDRERRRK 105
R R GS+ RS K A+ + R +RERD+ R++ +K+RDRD+ +RD++R+R
Sbjct: 52 RRRGGSRSRSRS-----RSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRS 106
Query: 106 EKETNRNRDREKQTEIERDREREKQKG--------------------------------- 132
R +D + + + + ++ E + G
Sbjct: 107 SLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSK 166
Query: 133 --RERERDRGRERE---RDRDREKERERQTEKDRDGQRETETERERDR-EREKQKERETE 186
RE E + R++E R R E+ER+++ + G++ E +ER+R ER ++ ERET
Sbjct: 167 AEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETN 226
Query: 187 RDRDRQ------RDTEKERERQTDRER-----DRQRKTQTERQRETDREGERETD----- 230
+ D + + +K +E +ER ++R+T+ R+ E + D
Sbjct: 227 GNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDY 286
Query: 231 ----RRRERQRDRDRG-------KERDRERDR-------KEERKKERKKERKKERKEKKK 272
+ R + + RG K++ RE+ R K +E+++E + RK +KK
Sbjct: 287 NPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKK 346
Query: 273 EEKRREDKKRKWGE 286
E K+R D R W +
Sbjct: 347 EAKQRWD-DRHWSQ 359
Score = 35.8 bits (81), Expect = 0.045
Identities = 36/161 (22%), Positives = 75/161 (46%), Gaps = 30/161 (18%)
Query: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDR-----ERRRKEKETNR 111
QE R + ++ +G++ + R ++RE+ +K ++ ++R ++RR+ + N
Sbjct: 210 QERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLND 269
Query: 112 NR-----DREKQTEIERD---RERE---------------KQKGRERERDRGRERERDRD 148
+ D + T I+ + +ER KQ+ RE+ R G E+ R
Sbjct: 270 RKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRT 329
Query: 149 REKERERQTEKDRDGQRETETERERDRE-REKQKERETERD 188
E E+E++ + R +++ +R DR +K+ + T+RD
Sbjct: 330 LE-EKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRD 369
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.128 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,315,566
Number of Sequences: 37866
Number of extensions: 758904
Number of successful extensions: 92186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1564
Number of HSP's successfully gapped in prelim test: 788
Number of HSP's that attempted gapping in prelim test: 9666
Number of HSP's gapped (non-prelim): 26774
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.