Guide to the Human Genome
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Search of human proteins with 239754606

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]          606   e-174
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]          502   e-142
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]          502   e-142
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi...   390   e-108
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap...   350   7e-97
gi|14670354 general transcription factor II, i isoform 3 [Homo s...   131   6e-31
gi|14670352 general transcription factor II, i isoform 2 [Homo s...   131   6e-31
gi|14670350 general transcription factor II, i isoform 1 [Homo s...   131   6e-31
gi|169881252 general transcription factor II, i isoform 4 [Homo ...   131   6e-31
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]            88   1e-17
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]           88   1e-17
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti...    38   0.012
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ...    38   0.012
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap...    36   0.047
gi|217416392 pleckstrin homology domain containing, family H (wi...    32   0.88 
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      30   2.6  
gi|34577118 dopey family member 1 [Homo sapiens]                       29   5.7  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                   28   7.5  

>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 298

 Score =  606 bits (1562), Expect = e-174
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
           MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60

Query: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
           GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120

Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180
           TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180

Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240
           TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC
Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240

Query: 241 NDAKVPGESEARKPPFCPVGTRLFLLKKREPEVSMNKDRYPQEAPRNLQVPYRGKALP 298
           NDAKVPGESEARKPPFCPVGTRLFLLKKREPEVSMNKDRYPQEAPRNLQVPYRGKALP
Sbjct: 241 NDAKVPGESEARKPPFCPVGTRLFLLKKREPEVSMNKDRYPQEAPRNLQVPYRGKALP 298


>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  502 bits (1293), Expect = e-142
 Identities = 248/250 (99%), Positives = 249/250 (99%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
           MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60

Query: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
           GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120

Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180
           TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180

Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240
           TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC
Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240

Query: 241 NDAKVPGESE 250
           NDAKVPG +E
Sbjct: 241 NDAKVPGYTE 250


>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  502 bits (1293), Expect = e-142
 Identities = 248/250 (99%), Positives = 249/250 (99%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
           MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60

Query: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
           GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120

Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180
           TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180

Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240
           TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC
Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240

Query: 241 NDAKVPGESE 250
           NDAKVPG +E
Sbjct: 241 NDAKVPGYTE 250


>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 959

 Score =  390 bits (1001), Expect = e-108
 Identities = 215/301 (71%), Positives = 231/301 (76%), Gaps = 50/301 (16%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
           MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPI+DSQ
Sbjct: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQ 655

Query: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
           GTASSLGFSPPALPPERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK
Sbjct: 656 GTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 715

Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178
            YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP  FGSQNLERILA+A+KI F
Sbjct: 716 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 775

Query: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222
           TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L               
Sbjct: 776 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 835

Query: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVPGESE 250
                                       L+ ++H     I++ +PFAEICNDAKVP +  
Sbjct: 836 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDS 895

Query: 251 A 251
           +
Sbjct: 896 S 896



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 61/218 (27%), Positives = 88/218 (40%), Gaps = 49/218 (22%)

Query: 52  VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108
           ++  + D   T+  +  S P   P  DS    + L  + L      E         D+  
Sbjct: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
            LR+QV+ LFN  Y +A+GI  PV+VPY     +P  + +  LP GI  R+P  FG   L
Sbjct: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623

Query: 167 ERILAMANKITFTVTRP-------------FQGLIRK--------PDEDDTN-------- 197
            +IL  +N I F + RP              QG            P E D+         
Sbjct: 624 RKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL 683

Query: 198 -----------RLGEV----ILQEQVKELFNEKYSQCL 220
                      RL  +     L+EQV++LFN+KY + L
Sbjct: 684 KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEAL 721



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)

Query: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
           E +DA +   +  NTLRE VQ LFN  Y EALG+ + V VPY+ I  +P ++ I  +P  
Sbjct: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395

Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184
           I F++P  +G   L+RIL   + I F + R F
Sbjct: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 70  PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129
           P A  P++  R    G SL R   +   D  LLR        + V+E+F+  Y EALG  
Sbjct: 96  PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147

Query: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185
             V +PY+ +   PG + ++ LP G+ FR+P  +  + L  IL  +++I F + RP +
Sbjct: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE + +VG+P+ I  +RP  +G+ KL +ILE  +SI F+IKR         E I      
Sbjct: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437

Query: 63  ASSLGFSPPALPPERDSRD 81
                   PA PPE  S +
Sbjct: 438 TKDTTKLEPASPPEDTSAE 456



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54
           P  L V GLPEG++ RRP  +    L  ILE S+ I+F +KRP        K L E    
Sbjct: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220

Query: 55  PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114
            ++        L    P +PP+     P    S     F   Y   L      + +RE  
Sbjct: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271

Query: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171
           QE  +     + LG+  P+  P K   +   S    + P G     P G   QN+     
Sbjct: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325

Query: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222
           +   I    +  +   I++ ++ +T       L+E V+ LFN +Y++ L L
Sbjct: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369


>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score =  350 bits (899), Expect = 7e-97
 Identities = 201/301 (66%), Positives = 216/301 (71%), Gaps = 65/301 (21%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
           MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPIVDSQ
Sbjct: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ 655

Query: 61  GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
                          ERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK
Sbjct: 656 ---------------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 700

Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178
            YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP  FGSQNLERILA+A+KI F
Sbjct: 701 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 760

Query: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222
           TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L               
Sbjct: 761 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 820

Query: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVPGESE 250
                                       L+ ++H     I++ +PFAEICNDAKVP +  
Sbjct: 821 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDS 880

Query: 251 A 251
           +
Sbjct: 881 S 881



 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 34/203 (16%)

Query: 52  VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108
           ++  + D   T+  +  S P   P  DS    + L  + L      E         D+  
Sbjct: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
            LR+QV+ LFN  Y +A+GI  PV+VPY     +P  + +  LP GI  R+P  FG   L
Sbjct: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623

Query: 167 ERILAMANKITFTVTRP--FQGLIRKP-----------------------DEDDTNRLGE 201
            +IL  +N I F + RP      +++P                        E+   RL  
Sbjct: 624 RKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSR 683

Query: 202 V----ILQEQVKELFNEKYSQCL 220
           +     L+EQV++LFN+KY + L
Sbjct: 684 IDIANTLREQVQDLFNKKYGEAL 706



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)

Query: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
           E +DA +   +  NTLRE VQ LFN  Y EALG+ + V VPY+ I  +P ++ I  +P  
Sbjct: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395

Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184
           I F++P  +G   L+RIL   + I F + R F
Sbjct: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 70  PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129
           P A  P++  R    G SL R   +   D  LLR        + V+E+F+  Y EALG  
Sbjct: 96  PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147

Query: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185
             V +PY+ +   PG + ++ LP G+ FR+P  +  + L  IL  +++I F + RP +
Sbjct: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE + +VG+P+ I  +RP  +G+ KL +ILE  +SI F+IKR         E I      
Sbjct: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437

Query: 63  ASSLGFSPPALPPERDSRD 81
                   PA PPE  S +
Sbjct: 438 TKDTTKLEPASPPEDTSAE 456



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54
           P  L V GLPEG++ RRP  +    L  ILE S+ I+F +KRP        K L E    
Sbjct: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220

Query: 55  PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114
            ++        L    P +PP+     P    S     F   Y   L      + +RE  
Sbjct: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271

Query: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171
           QE  +     + LG+  P+  P K   +   S    + P G     P G   QN+     
Sbjct: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325

Query: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222
           +   I    +  +   I++ ++ +T       L+E V+ LFN +Y++ L L
Sbjct: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369


>gi|14670354 general transcription factor II, i isoform 3 [Homo
           sapiens]
          Length = 977

 Score =  131 bits (330), Expect = 6e-31
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 745 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 796

Query: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 797 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 855

Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 856 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 915

Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
            FTV RPF GL+      D +     ++QE  +
Sbjct: 916 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 948



 Score =  111 bits (278), Expect = 7e-25
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 477 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 529

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 530 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 561

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 562 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 621

Query: 180 VTRP 183
           V +P
Sbjct: 622 VKKP 625



 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 372 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 420

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 421 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 456

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 457 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 516

Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 517 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 570



 Score =  101 bits (251), Expect = 9e-22
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 582 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 640

Query: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 641 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 700

Query: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 701 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 757

Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 758 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 817

Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 818 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 863



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 297 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 353

Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 354 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 413

Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 414 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 461



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170

Query: 167 ERILAMANKITFTVTRPF 184
           + IL     I+F + RPF
Sbjct: 171 KWILENKAGISFIIKRPF 188



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 878 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 922


>gi|14670352 general transcription factor II, i isoform 2 [Homo
           sapiens]
          Length = 978

 Score =  131 bits (330), Expect = 6e-31
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 797

Query: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 798 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 856

Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 857 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 916

Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
            FTV RPF GL+      D +     ++QE  +
Sbjct: 917 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 949



 Score =  111 bits (278), Expect = 7e-25
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 478 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 530

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 531 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 562

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 563 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 622

Query: 180 VTRP 183
           V +P
Sbjct: 623 VKKP 626



 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 373 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 421

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 422 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 457

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 458 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 517

Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 518 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 571



 Score =  101 bits (251), Expect = 9e-22
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 583 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 641

Query: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 642 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701

Query: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 702 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 758

Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 759 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 818

Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 819 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 864



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 298 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 354

Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 355 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 414

Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 415 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 462



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170

Query: 167 ERILAMANKITFTVTRPF 184
           + IL     I+F + RPF
Sbjct: 171 KWILENKAGISFIIKRPF 188



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 879 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 923


>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score =  131 bits (330), Expect = 6e-31
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 766 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 817

Query: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 818 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 876

Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 877 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 936

Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
            FTV RPF GL+      D +     ++QE  +
Sbjct: 937 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 969



 Score =  111 bits (278), Expect = 7e-25
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 498 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 550

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 551 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 582

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 583 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 642

Query: 180 VTRP 183
           V +P
Sbjct: 643 VKKP 646



 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 393 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 441

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 442 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 477

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 478 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 537

Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 538 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 591



 Score =  101 bits (251), Expect = 9e-22
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 603 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 661

Query: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 662 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721

Query: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 722 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 778

Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 779 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 838

Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 839 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 884



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 318 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 374

Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 375 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 434

Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 435 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 482



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170

Query: 167 ERILAMANKITFTVTRPF 184
           + IL     I+F + RPF
Sbjct: 171 KWILENKAGISFIIKRPF 188



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 899 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 943


>gi|169881252 general transcription factor II, i isoform 4 [Homo
           sapiens]
          Length = 957

 Score =  131 bits (330), Expect = 6e-31
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 725 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 776

Query: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 777 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 835

Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 836 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 895

Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
            FTV RPF GL+      D +     ++QE  +
Sbjct: 896 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 928



 Score =  111 bits (278), Expect = 7e-25
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 457 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 509

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 510 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 541

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 542 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 601

Query: 180 VTRP 183
           V +P
Sbjct: 602 VKKP 605



 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 352 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 400

Query: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 401 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 436

Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 437 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 496

Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 497 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 550



 Score =  101 bits (251), Expect = 9e-22
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 562 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 620

Query: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 621 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680

Query: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 681 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 737

Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 738 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 797

Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 798 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 843



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 277 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 333

Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 334 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 393

Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 394 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 441



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170

Query: 167 ERILAMANKITFTVTRPF 184
           + IL     I+F + RPF
Sbjct: 171 KWILENKAGISFIIKRPF 188



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 858 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 902


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%)

Query: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
           +N   RL  I+    LREQV +LF++ +GEA+G+ +PV+VPY+ I  NPG ++I+ +PPG
Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376

Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212
           ++F+ P      ++ RIL  A  I FTV RP  GL       + + +G+  + +Q   +F
Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428

Query: 213 NEKYSQCLWLLQQQ 226
            EK+ +  + ++ Q
Sbjct: 429 QEKWERAYFFVEVQ 442



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167
           LR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 168 RILAMANKITFTVTRPFQG 186
            IL     I+F + RPF G
Sbjct: 167 WILENKAGISFIINRPFLG 185



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60
           V GLPEG++ + P  + +A L  ILE    I F+I RP L  E   G    + D++    
Sbjct: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204

Query: 61  GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97
             + S G       P  DS   L  E  S+K++    NY
Sbjct: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 14/44 (31%), Positives = 26/44 (59%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           +P  + + G+P G+  + P    I+ + +ILEA+  I+F + RP
Sbjct: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%)

Query: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
           +N   RL  I+    LREQV +LF++ +GEA+G+ +PV+VPY+ I  NPG ++I+ +PPG
Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376

Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212
           ++F+ P      ++ RIL  A  I FTV RP  GL       + + +G+  + +Q   +F
Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428

Query: 213 NEKYSQCLWLLQQQ 226
            EK+ +  + ++ Q
Sbjct: 429 QEKWERAYFFVEVQ 442



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167
           LR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 168 RILAMANKITFTVTRPFQG 186
            IL     I+F + RPF G
Sbjct: 167 WILENKAGISFIINRPFLG 185



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60
           V GLPEG++ + P  + +A L  ILE    I F+I RP L  E   G    + D++    
Sbjct: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204

Query: 61  GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97
             + S G       P  DS   L  E  S+K++    NY
Sbjct: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 14/44 (31%), Positives = 26/44 (59%)

Query: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
           +P  + + G+P G+  + P    I+ + +ILEA+  I+F + RP
Sbjct: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407


>gi|239752592 PREDICTED: hypothetical protein XP_002348308,
          partial [Homo sapiens]
          Length = 94

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 18/39 (46%), Positives = 25/39 (64%)

Query: 6  LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKR 44
          L V GLPEG++ + P  + +A L  ILE +  I F+IKR
Sbjct: 56 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165
           NT ++ V++ F     + L     V VPY+ +  +  ++I++ LP G+ F+ P  +    
Sbjct: 18  NTRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77

Query: 166 LERILAMANKITFTVTR 182
           LE IL     I+F + R
Sbjct: 78  LEWILEYTAGISFIIKR 94


>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
           sapiens]
          Length = 145

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 18/39 (46%), Positives = 25/39 (64%)

Query: 6   LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKR 44
           L V GLPEG++ + P  + +A L  ILE +  I F+IKR
Sbjct: 107 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 145



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)

Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165
           NT ++ V++ F     +AL     V VPY+ +  +  ++I++ LP G+ F+ P  +    
Sbjct: 69  NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 128

Query: 166 LERILAMANKITFTVTR 182
           LE IL     I+F + R
Sbjct: 129 LEWILEYTAGISFIIKR 145


>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
          sapiens]
          Length = 304

 Score = 35.8 bits (81), Expect = 0.047
 Identities = 17/38 (44%), Positives = 24/38 (63%)

Query: 6  LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIK 43
          L V GLPEG++ + P  + +A L  ILE +  I F+IK
Sbjct: 56 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIK 93



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165
           NT ++ V++ F     +AL     V VPY+ +  +  ++I++ LP G+ F+ P  +    
Sbjct: 18  NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77

Query: 166 LERILAMANKITFTV 180
           LE IL     I+F +
Sbjct: 78  LEWILEYTAGISFII 92


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 31.6 bits (70), Expect = 0.88
 Identities = 30/133 (22%), Positives = 52/133 (39%), Gaps = 12/133 (9%)

Query: 164 QNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLL 223
           QNLE  L    +I     +  +    K  E  T +L E+ L+ Q   L N+  ++ +  +
Sbjct: 103 QNLELQLEEQKQIRIQEAKIIEEKAAKIKEWVTVKLNELELENQNLRLINQNQTEEIRTM 162

Query: 224 QQQQHHISEGRPFAEICNDAKVPGE-----------SEARKPPFCPVGTRLFLLKKREPE 272
           Q +   + +G+  + +       G+           S AR PP       +  +  +EPE
Sbjct: 163 QSKLQEV-QGKKSSTVSTLKLSEGQRLSSLTFGCFLSRARSPPQVVKSEEMSKISSKEPE 221

Query: 273 VSMNKDRYPQEAP 285
            +  KD    E P
Sbjct: 222 FTEGKDMEEMEIP 234


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)

Query: 47  LLTEGVKEPIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDI 106
           +L +  K PI   +    +L   P A PPE  S   L  E +KR   QE    R LRI +
Sbjct: 937 ILKQAAKPPISKKKAVLQALEVLPVAPPPEPRS---LTAEEVKRLEEQEEDTFRELRIFL 993

Query: 107 AN 108
            N
Sbjct: 994 RN 995


>gi|34577118 dopey family member 1 [Homo sapiens]
          Length = 2465

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 3/38 (7%)

Query: 182 RPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQC 219
           +PF+ LI   D+ +   LG VIL++ + E+F   YSQC
Sbjct: 352 KPFRILISLLDKPE---LGPVILEDVLIEVFRTLYSQC 386


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 13/41 (31%), Positives = 21/41 (51%)

Query: 257 CPVGTRLFLLKKREPEVSMNKDRYPQEAPRNLQVPYRGKAL 297
           C     L L  K+  ++++N  R+P+  PR L VP  G  +
Sbjct: 184 CMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVPVAGSCV 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,773,507
Number of Sequences: 37866
Number of extensions: 593647
Number of successful extensions: 1671
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1543
Number of HSP's gapped (non-prelim): 79
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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