Guide to the Human Genome
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Name: PLCG2 Sequence: fasta or formatted (1265aa) NCBI GI: 117320537
Description:

phospholipase C, gamma 2

Referenced in:

Inositol Pathways
Lipid Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.6         58           2
 C cysteine            1.7         21           2
 D aspartate           6.4         81           2
 E glutamate           8.5        108           3
 F phenylalanine       5.1         64           1
 G glycine             3.9         49           2
 H histidine           2.3         29           1
 I isoleucine          5.2         66           3
 K lysine              7.4         94           2
 L leucine             8.8        111           3
 M methionine          2.5         32           1
 N asparagine          4.2         53           2
 P proline             4.3         55           2
 Q glutamine           4.4         56           2
 R arginine            6.5         82           3
 S serine              7.5         95           3
 T threonine           5.3         67           2
 V valine              5.6         71           2
 W tryptophan          1.6         20           2
 Y tyrosine            4.2         53           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phospholipase C, gamma 2 
PLCG1                 0.474   phospholipase C, gamma 1 isoform b 
PLCG1                 0.473   phospholipase C, gamma 1 isoform a 
PLCD1                 0.085   phospholipase C, delta 1 isoform 2 
PLCD1                 0.085   phospholipase C, delta 1 isoform 1 
PLCH1                 0.082   phospholipase C eta 1 isoform c 
PLCH1                 0.082   phospholipase C eta 1 isoform a 
PLCH1                 0.082   phospholipase C eta 1 isoform b 
PLCH2                 0.081   phospholipase C, eta 2 
PLCD3                 0.080   phospholipase C delta 3 
PLCD4                 0.076   phospholipase C, delta 4 
PLCL2                 0.074   phospholipase C-like 2 isoform 1 
PLCL2                 0.074   phospholipase C-like 2 isoform 2 
PLCL1                 0.068   phospholipase C-like 1 isoform a 
PLCL1                 0.068   phospholipase C-like 1 isoform b 
PLCE1                 0.064   phospholipase C, epsilon 1 
PLCB4                 0.058   phospholipase C beta 4 isoform a 
PLCB4                 0.058   phospholipase C beta 4 isoform b 
PLCZ1                 0.058   phospholipase C, zeta 1 
PLCB1                 0.052   phosphoinositide-specific phospholipase C beta 1 iso...
PLCB1                 0.052   phosphoinositide-specific phospholipase C beta 1 iso...
PLCB3                 0.050   phospholipase C beta 3 
PLCB2                 0.049   phospholipase C, beta 2 
PTPN11                0.024   protein tyrosine phosphatase, non-receptor type 11 [...
VAV3                  0.022   vav 3 guanine nucleotide exchange factor isoform 2 ...
VAV3                  0.022   vav 3 guanine nucleotide exchange factor isoform 1 ...
GRB2                  0.020   growth factor receptor-bound protein 2 isoform 1 [Hom...
VAV2                  0.020   vav 2 guanine nucleotide exchange factor isoform 2 [...
VAV2                  0.019   vav 2 guanine nucleotide exchange factor isoform 1 ...
RASA1                 0.018   RAS p21 protein activator 1 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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