Search of human proteins with 116812644

Search of human proteins with 116812644

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                  946   0.0  
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]                   493   e-139
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]                  229   5e-60
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]                  229   5e-60
gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]                  229   5e-60
gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]                  229   5e-60
gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]                  229   5e-60
gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]                  229   5e-60
gi|4505151 Meis homeobox 1 [Homo sapiens]                             226   5e-59
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]                  204   2e-52
gi|57863281 Meis1, myeloid ecotropic viral integration site 1 ho...   200   2e-51
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...   182   6e-46
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ...    84   4e-16
gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo ...    82   1e-15
gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]              80   3e-15
gi|28178843 TG-interacting factor isoform a [Homo sapiens]             80   4e-15
gi|4507473 TG-interacting factor isoform c [Homo sapiens]              80   4e-15
gi|28178855 TG-interacting factor isoform d [Homo sapiens]             80   4e-15
gi|28178853 TG-interacting factor isoform d [Homo sapiens]             80   4e-15
gi|28178851 TG-interacting factor isoform d [Homo sapiens]             80   4e-15
gi|28178857 TG-interacting factor isoform d [Homo sapiens]             80   4e-15
gi|28178849 TG-interacting factor isoform c [Homo sapiens]             80   4e-15
gi|28178845 TG-interacting factor isoform b [Homo sapiens]             80   4e-15
gi|42544241 iroquois homeobox protein 6 [Homo sapiens]                 68   2e-11
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi...    66   8e-11
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]     66   8e-11
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]              61   3e-09
gi|197100900 iroquois homeobox 2 [Homo sapiens]                        60   3e-09
gi|39930475 iroquois homeobox 2 [Homo sapiens]                         60   3e-09
gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]              60   4e-09

>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score =  946 bits (2445), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP 60
           MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP
Sbjct: 1   MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP 60

Query: 61  IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH 120
           IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH
Sbjct: 61  IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH 120

Query: 121 KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL 180
           KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL
Sbjct: 121 KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL 180

Query: 181 GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG 240
           GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG
Sbjct: 181 GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG 240

Query: 241 GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHAT 300
           GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHAT
Sbjct: 241 GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHAT 300

Query: 301 NIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAP 360
           NIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAP
Sbjct: 301 NIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAP 360

Query: 361 KAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQA 420
           KAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQA
Sbjct: 361 KAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQA 420

Query: 421 MMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE 472
           MMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE
Sbjct: 421 MMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE 472


>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
          Length = 436

 Score =  493 bits (1269), Expect = e-139
 Identities = 271/471 (57%), Positives = 331/471 (70%), Gaps = 46/471 (9%)

Query: 13  MMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKR 72
           MMATQ +    YQD  QM    +  ++ Q  + S P A   +P    P++ Q  ++ DK+
Sbjct: 1   MMATQTLSIDSYQDGQQMQVVTELKTE-QDPNCSEPDAEGVSP---PPVESQTPMDVDKQ 56

Query: 73  AVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDN 132
           A+YRHPLFPLL LLFEKCEQ+TQGSE  TSASFDVDIENFV +QE+E KPFF +DPE DN
Sbjct: 57  AIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDN 116

Query: 133 LMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSIN 192
           LMVKAIQVLRIHLLELEKVNELCKDFC+RYI CLKTKM+S+ LL  + G PYSP Q    
Sbjct: 117 LMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQS--- 173

Query: 193 LHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTS 252
                  Q   ++++G + +PQGIVVPASALQQGN+AM T     V+GG +YQPVT+VT 
Sbjct: 174 -------QQIQSAITG-TISPQGIVVPASALQQGNVAMAT-----VAGGTVYQPVTVVTP 220

Query: 253 QGQVVTQAIPQGAIQIQNTQVNLDLT---SLLDNEDKKSKNKRGVLPKHATNIMRSWLFQ 309
           QGQVVTQ +  G I+IQN+Q+ L L    S+L  +D  SKNKRGVLPKHATN+MRSWLFQ
Sbjct: 221 QGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQ 280

Query: 310 HLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQH 369
           H+ HPYPTEDEK+QIAAQTNLTLLQVNNWFINARRRILQPMLD+S  +  PK KK  +Q+
Sbjct: 281 HIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSE-TPKTKKKTAQN 339

Query: 370 RPTQRFWPNSIAAGVLQ--------QQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQAM 421
           RP QRFWP+SIA+GV Q         +G         ++N+D+LQSLSSD AT+A+QQ M
Sbjct: 340 RPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVM 399

Query: 422 MAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE 472
           MA               + E+E  +  EE+   L   ++S L LE+SDSL+
Sbjct: 400 MAG--------------QSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ 436


>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
          Length = 388

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 16  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 66

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 67  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 125

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 126 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 184

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 185 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 226

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 227 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 276

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 277 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 330


>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
          Length = 401

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 29  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 79

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 80  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 138

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 139 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 197

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 198 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 239

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 240 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 289

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 290 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 343


>gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]
          Length = 470

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 29  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 79

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 80  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 138

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 139 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 197

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 198 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 239

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 240 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 289

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 290 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 343


>gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]
          Length = 477

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 29  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 79

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 80  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 138

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 139 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 197

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 198 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 239

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 240 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 289

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 290 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 343


>gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]
          Length = 394

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 29  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 79

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 80  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 138

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 139 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 197

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 198 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 239

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 240 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 289

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 290 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 343


>gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]
          Length = 381

 Score =  229 bits (583), Expect = 5e-60
 Identities = 146/354 (41%), Positives = 197/354 (55%), Gaps = 52/354 (14%)

Query: 15  ATQNVPPPPYQD-SPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRA 73
           A + +PP  + +  P + AT      A A H +   A+  + V  A       L+ DK A
Sbjct: 16  APRPIPPVHHLNHGPPLHATQH--YGAHAPHPNVMPASMGSAVNDA-------LKRDKDA 66

Query: 74  VYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFS 125
           +Y HPLFPLL L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS
Sbjct: 67  IYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFS 125

Query: 126 DDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYS 185
            +PELDNLM++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G   
Sbjct: 126 SNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSK 184

Query: 186 PNQPSINLHSQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
            +   ++  S +L  ++P+S        S +  G   P+                  SGG
Sbjct: 185 SDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPS------------------SGG 226

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
              Q     + QG  +  ++        +            ++DKK + KRG+ PK ATN
Sbjct: 227 HASQSGDNSSEQGDGLDNSVASPGTGDDDD----------PDKDKKRQKKRGIFPKVATN 276

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 277 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 330


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score =  226 bits (575), Expect = 5e-59
 Identities = 138/318 (43%), Positives = 182/318 (57%), Gaps = 42/318 (13%)

Query: 49  SAAASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQAT--------QGSECI 100
           +A  +   PS        L+ DK A+Y HPLFPLL L+FEKCE AT         G +  
Sbjct: 53  TAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVC 112

Query: 101 TSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCN 160
           +S SF+ DI  F  Q   E KP FS +PELDNLM++AIQVLR HLLELEKV+ELC +FC+
Sbjct: 113 SSESFNEDIAVFAKQIRAE-KPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH 171

Query: 161 RYITCLKTKMHSDNLLRNDLGGPYSPNQP---SINLHSQDLLQNSPNSMSGVSNNPQGIV 217
           RYI+CLK KM  D ++ +  GG  S ++    S NL  Q       +  +  S    G  
Sbjct: 172 RYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTA--STRSGGTP 229

Query: 218 VPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDL 277
            P+S    G+ + +  NS               + QG  +  ++   +    +       
Sbjct: 230 GPSSG---GHTSHSGDNS---------------SEQGDGLDNSVASPSTGDDDD------ 265

Query: 278 TSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNN 337
                ++DKK   KRG+ PK ATNIMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNN
Sbjct: 266 ----PDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNN 321

Query: 338 WFINARRRILQPMLDASN 355
           WFINARRRI+QPM+D SN
Sbjct: 322 WFINARRRIVQPMIDQSN 339


>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
          Length = 306

 Score =  204 bits (518), Expect = 2e-52
 Identities = 122/285 (42%), Positives = 164/285 (57%), Gaps = 42/285 (14%)

Query: 83  LTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLM 134
           + L+FEKCE AT         G +  +S SF+ DI  F  Q   E KP FS +PELDNLM
Sbjct: 1   MALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAE-KPLFSSNPELDNLM 59

Query: 135 VKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLH 194
           ++AIQVLR HLLELEKV+ELC +FC+RYI+CLK KM  D L+ ++  G    +   ++  
Sbjct: 60  IQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPID-LVIDERDGSSKSDHEELSGS 118

Query: 195 SQDLLQNSPNSM----SGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMV 250
           S +L  ++P+S        S +  G   P+S                  GG   Q     
Sbjct: 119 STNLADHNPSSWRDHDDATSTHSAGTPGPSS------------------GGHASQSGDNS 160

Query: 251 TSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQH 310
           + QG  +  ++        +            ++DKK + KRG+ PK ATNIMR+WLFQH
Sbjct: 161 SEQGDGLDNSVASPGTGDDDDP----------DKDKKRQKKRGIFPKVATNIMRAWLFQH 210

Query: 311 LMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           L HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 211 LTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 255


>gi|57863281 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 1 [Homo sapiens]
          Length = 421

 Score =  200 bits (509), Expect = 2e-51
 Identities = 146/400 (36%), Positives = 191/400 (47%), Gaps = 102/400 (25%)

Query: 22  PPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRAVYRHPLFP 81
           P   D P   A A  P    AV    P      P P  P      L+ +K  +Y HPLFP
Sbjct: 12  PGIVDGP--AALASFPETVPAV--PGPYGPHRPPQPLPPGLDSDGLKREKDEIYGHPLFP 67

Query: 82  LLTLLFEKCEQAT--------------QGSECITSASFDVDIENFVHQQEQEHKPFFSDD 127
           LL L+FEKCE AT               G +  +S SF+ DI  F  Q   E +P FS +
Sbjct: 68  LLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSE-RPLFSSN 126

Query: 128 PELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGG----- 182
           PELDNLM++AIQVLR HLLELEKV++LC +FC+RYITCLK KM  D ++ +  GG     
Sbjct: 127 PELDNLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDGGCREDF 186

Query: 183 -PYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
             Y  + PS+   +   +++  +S S     P     P+S    G +A  + ++    G 
Sbjct: 187 EDYPASCPSLPDQNNMWIRDHEDSGSVHLGTPG----PSS----GGLASQSGDNSSDQGD 238

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
            L   V   +S G+                         LD E +++K KRG+ PK ATN
Sbjct: 239 GLDTSVASPSSGGE----------------------DEDLDQERRRNK-KRGIFPKVATN 275

Query: 302 IMRSWLFQH----------------------------------------------LMHPY 315
           IMR+WLFQH                                              L HPY
Sbjct: 276 IMRAWLFQHLSRRSEAPVLPDVCLGLGSPSPGPRWARPWGSDCGRPGRQSDSCWWLQHPY 335

Query: 316 PTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           P+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 336 PSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 375


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score =  182 bits (462), Expect = 6e-46
 Identities = 134/354 (37%), Positives = 175/354 (49%), Gaps = 73/354 (20%)

Query: 22  PPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRAVYRHPLFP 81
           P   D P   A A  P    AV    P      P P  P      L+ +K  +Y HPLFP
Sbjct: 12  PGIVDGP--AALASFPETVPAV--PGPYGPHRPPQPLPPGLDSDGLKREKDEIYGHPLFP 67

Query: 82  LLTLLFEKCEQAT--------------QGSECITSASFDVDIENFVHQQEQEHKPFFSDD 127
           LL L+FEKCE AT               G +  +S SF+ DI  F  Q   E +P FS +
Sbjct: 68  LLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSE-RPLFSSN 126

Query: 128 PELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGG----- 182
           PELDNLM++AIQVLR HLLELEK                  KM  D ++ +  GG     
Sbjct: 127 PELDNLMIQAIQVLRFHLLELEK-----------------GKMPIDLVIEDRDGGCREDF 169

Query: 183 -PYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGG 241
             Y  + PS+   +   +++  +S S     P     P+S    G +A  + ++    G 
Sbjct: 170 EDYPASCPSLPDQNNMWIRDHEDSGSVHLGTPG----PSS----GGLASQSGDNSSDQGD 221

Query: 242 ALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATN 301
            L   V   +S G+                         LD E +++K KRG+ PK ATN
Sbjct: 222 GLDTSVASPSSGGE----------------------DEDLDQERRRNK-KRGIFPKVATN 258

Query: 302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASN 355
           IMR+WLFQHL HPYP+E++K+Q+A  T LT+LQVNNWFINARRRI+QPM+D SN
Sbjct: 259 IMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSN 312


>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
           sapiens]
          Length = 241

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)

Query: 274 NLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLL 333
           N D   +L   + K K K G LP  +  I+R W+++H    YP+E+EK+ ++ +TNL+LL
Sbjct: 37  NADTGRVLALPEHKKKRK-GNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLL 95

Query: 334 QVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQH 369
           Q++NWFINARRRIL  ML     DP    K  K  H
Sbjct: 96  QISNWFINARRRILPDMLQQRRNDPIIGHKTGKDAH 131


>gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo
           sapiens]
          Length = 185

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 1/96 (1%)

Query: 274 NLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLL 333
           N D   +L   + K K K G LP  +  I+R W+++H    YP+E+EK+ ++ +TNL+LL
Sbjct: 37  NADTGRVLALPEHKKKRK-GNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLL 95

Query: 334 QVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQH 369
           +++NWFINARRRIL  ML     DP    K  K  H
Sbjct: 96  RISNWFINARRRILPDMLQQRRNDPIIGHKTGKDAH 131


>gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]
          Length = 237

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 35/70 (50%), Positives = 48/70 (68%)

Query: 289 KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQ 348
           + +RG LPK +  I+R WL+ H  + YP+E EK  ++ QTNL++LQ+ NWFINARRR+L 
Sbjct: 19  RKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLP 78

Query: 349 PMLDASNPDP 358
            ML     DP
Sbjct: 79  DMLRKDGKDP 88


>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
          Length = 401

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 152 IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 208

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 209 LQVCNWFINARRRLLPDMLRKDGKDP 234


>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 23  IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 79

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 80  LQVCNWFINARRRLLPDMLRKDGKDP 105


>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 3   IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 59

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 60  LQVCNWFINARRRLLPDMLRKDGKDP 85


>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 3   IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 59

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 60  LQVCNWFINARRRLLPDMLRKDGKDP 85


>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 3   IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 59

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 60  LQVCNWFINARRRLLPDMLRKDGKDP 85


>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 3   IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 59

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 60  LQVCNWFINARRRLLPDMLRKDGKDP 85


>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 23  IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 79

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 80  LQVCNWFINARRRLLPDMLRKDGKDP 105


>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
          Length = 286

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 39/86 (45%), Positives = 55/86 (63%), Gaps = 3/86 (3%)

Query: 273 VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTL 332
           + LDL+S   +     + +RG LPK +  I+R WL++H  + YP+E EK  ++ QT+L+ 
Sbjct: 37  IPLDLSS---SAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 93

Query: 333 LQVNNWFINARRRILQPMLDASNPDP 358
           LQV NWFINARRR+L  ML     DP
Sbjct: 94  LQVCNWFINARRRLLPDMLRKDGKDP 119


>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
          Length = 446

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 33/160 (20%)

Query: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356
           +  T+ +++WL +H  +PYPT+ EK  +A  T +TL QV+ WF NARRR+          
Sbjct: 155 RETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL---------- 204

Query: 357 DPAPKAKKIKSQHRPTQRFW-PNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATM 415
                    K +++ T   W P +      + +GG            D+L  L++D+  +
Sbjct: 205 ---------KKENKMT---WAPKNKGGEERKAEGGEE----------DSLGCLTADTKEV 242

Query: 416 AMQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDEL 455
              Q         L+  EEE+E+E E E+EE +    D L
Sbjct: 243 TASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRL 282


>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
           sapiens]
          Length = 359

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 18/175 (10%)

Query: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324
           +IQ+Q  Q   +   +L +    ++ KR    K AT I+  + + HL +PYP+E+ K ++
Sbjct: 137 SIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEEL 196

Query: 325 AAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGV 384
           A + ++T+ QV+NWF N R R  + +           AK        T     +++AA V
Sbjct: 197 AKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAK--------TAVTAAHAVAAAV 248

Query: 385 LQQQGGAPGT---NPDGSINLD-------NLQSLSSDSATMAMQQAMMAAHDDSL 429
              Q  +P T      GS NL        N+QSL+ DS   +   A + +  D+L
Sbjct: 249 QNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTL 303


>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
          Length = 434

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 18/175 (10%)

Query: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324
           +IQ+Q  Q   +   +L +    ++ KR    K AT I+  + + HL +PYP+E+ K ++
Sbjct: 212 SIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEEL 271

Query: 325 AAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGV 384
           A + ++T+ QV+NWF N R R  + +           AK        T     +++AA V
Sbjct: 272 AKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAK--------TAVTAAHAVAAAV 323

Query: 385 LQQQGGAPGT---NPDGSINLD-------NLQSLSSDSATMAMQQAMMAAHDDSL 429
              Q  +P T      GS NL        N+QSL+ DS   +   A + +  D+L
Sbjct: 324 QNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTL 378


>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
          Length = 430

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 28/81 (34%), Positives = 47/81 (58%)

Query: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324
           AIQ+Q  Q   +   +L +    ++ KR    K AT ++  + + HL +PYP+E+ K ++
Sbjct: 221 AIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEEL 280

Query: 325 AAQTNLTLLQVNNWFINARRR 345
           A +  +T+ QV+NWF N R R
Sbjct: 281 AKKCGITVSQVSNWFGNKRIR 301


>gi|197100900 iroquois homeobox 2 [Homo sapiens]
          Length = 471

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 44/157 (28%), Positives = 78/157 (49%), Gaps = 7/157 (4%)

Query: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356
           + AT  +++WL +H  +PYPT+ EK  +A  T +TL QV+ WF NARRR+ +   +    
Sbjct: 123 RDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKE--NKMTW 180

Query: 357 DPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDG-SINLDNLQSLSSDSATM 415
            P  K++          R    S       Q+G       +G S+++D+L   S  + + 
Sbjct: 181 APRNKSEDEDEDEGDATRSKDESPDKA---QEGTETSAEDEGISLHVDSLTDHSCSAESD 237

Query: 416 AMQQAMMAAHDDSLDGTEEEDE-DEMEEEEEEELEEE 451
             +    A       G+E +D+ D++E++E+++ E E
Sbjct: 238 GEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGE 274


>gi|39930475 iroquois homeobox 2 [Homo sapiens]
          Length = 471

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 44/157 (28%), Positives = 78/157 (49%), Gaps = 7/157 (4%)

Query: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356
           + AT  +++WL +H  +PYPT+ EK  +A  T +TL QV+ WF NARRR+ +   +    
Sbjct: 123 RDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKE--NKMTW 180

Query: 357 DPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDG-SINLDNLQSLSSDSATM 415
            P  K++          R    S       Q+G       +G S+++D+L   S  + + 
Sbjct: 181 APRNKSEDEDEDEGDATRSKDESPDKA---QEGTETSAEDEGISLHVDSLTDHSCSAESD 237

Query: 416 AMQQAMMAAHDDSLDGTEEEDE-DEMEEEEEEELEEE 451
             +    A       G+E +D+ D++E++E+++ E E
Sbjct: 238 GEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGE 274


>gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
          Length = 374

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 30/86 (34%), Positives = 48/86 (55%)

Query: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324
           AIQ+Q  Q   +    L +    ++ KR    K AT ++  + + HL +PYP+E+ K ++
Sbjct: 187 AIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEEL 246

Query: 325 AAQTNLTLLQVNNWFINARRRILQPM 350
           A +  LT+ QV+NWF N R R  + M
Sbjct: 247 ARKGGLTISQVSNWFGNKRIRYKKNM 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,129,521
Number of Sequences: 37866
Number of extensions: 1041355
Number of successful extensions: 20092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 444
Number of HSP's successfully gapped in prelim test: 209
Number of HSP's that attempted gapping in prelim test: 11667
Number of HSP's gapped (non-prelim): 4540
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.