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Search of human proteins with 239745974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ... 1107 0.0
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ... 571 e-163
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 64 3e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 60 7e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens] 60 7e-09
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 59 9e-09
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 59 9e-09
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ... 57 4e-08
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 56 7e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 56 7e-08
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 56 9e-08
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 56 9e-08
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 56 9e-08
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 55 1e-07
gi|119508426 alpha 3 type IX collagen [Homo sapiens] 55 1e-07
gi|33286446 opioid growth factor receptor [Homo sapiens] 54 4e-07
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 54 4e-07
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 54 5e-07
gi|48762934 alpha 2 type I collagen [Homo sapiens] 53 6e-07
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 53 6e-07
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 53 6e-07
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 53 6e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 53 8e-07
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 52 1e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 52 1e-06
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 52 1e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 52 1e-06
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 52 1e-06
>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
sapiens]
Length = 538
Score = 1107 bits (2864), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MVFLPEPGCLRPPPARASPAPGSSVLWLSQRPSLAVSSRMVSFWLRMVSFCCSTVSRSCS 60
MVFLPEPGCLRPPPARASPAPGSSVLWLSQRPSLAVSSRMVSFWLRMVSFCCSTVSRSCS
Sbjct: 1 MVFLPEPGCLRPPPARASPAPGSSVLWLSQRPSLAVSSRMVSFWLRMVSFCCSTVSRSCS 60
Query: 61 TLLRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAA 120
TLLRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAA
Sbjct: 61 TLLRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAA 120
Query: 121 GTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAF 180
GTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAF
Sbjct: 121 GTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAF 180
Query: 181 YAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPP 240
YAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPP
Sbjct: 181 YAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPP 240
Query: 241 PPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLA 300
PPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLA
Sbjct: 241 PPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLA 300
Query: 301 ALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG 360
ALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG
Sbjct: 301 ALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG 360
Query: 361 PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR 420
PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR
Sbjct: 361 PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR 420
Query: 421 EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG 480
EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG
Sbjct: 421 EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG 480
Query: 481 LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHLSF 538
LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHLSF
Sbjct: 481 LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHLSF 538
>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
sapiens]
Length = 870
Score = 571 bits (1472), Expect = e-163
Identities = 308/430 (71%), Positives = 317/430 (73%), Gaps = 36/430 (8%)
Query: 114 RPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSG-PHCR 172
RP +A +GR G AR G G PAR R G + G P R
Sbjct: 472 RPGRVAGASGRRGASQARGGTGRA--PARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPR 529
Query: 173 LRCGARAFYAAAGGASS----RRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPP 228
R A S R GR P + G R G +A PGL
Sbjct: 530 ARADLEVLQAGFERLQSLPELAERLGGRCPGQVAHGVLARAGLLAAAARPGLA------- 582
Query: 229 FWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHR 288
G + +R L ++G GWTTCVVSPNLRRGSRRAGNHR
Sbjct: 583 --------------GSGV--QRALALAAAQLG------GWTTCVVSPNLRRGSRRAGNHR 620
Query: 289 VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 348
VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG
Sbjct: 621 VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 680
Query: 349 RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 408
RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW
Sbjct: 681 RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 740
Query: 409 TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL 468
TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL
Sbjct: 741 TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL 800
Query: 469 CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 528
CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA
Sbjct: 801 CVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 860
Query: 529 PAVCVQHLSF 538
PAVCVQHLSF
Sbjct: 861 PAVCVQHLSF 870
Score = 32.0 bits (71), Expect = 1.5
Identities = 50/177 (28%), Positives = 59/177 (33%), Gaps = 39/177 (22%)
Query: 108 AQVRAARPAGMAAGTGRSGPGSA----------RLGLGSGWDPARAVAPRAARALGAALF 157
A + P AG G GP S+ GL + P R R A L
Sbjct: 632 AALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 691
Query: 158 GRAVHTAALSGPH-CRLRCGA--------RAF-YAAAGGASSRRRQRGRNPALIVRGPGP 207
G LS P C G RAF AG + RRR+RG A +R P
Sbjct: 692 GPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAP 751
Query: 208 RRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264
R P P ASP + PR P PR LRG+ + PR
Sbjct: 752 RE-------QPPASPAASP---CQAPRAPEKETE-----APR----LRGRATAVAPR 789
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 64.3 bits (155), Expect = 3e-10
Identities = 105/356 (29%), Positives = 119/356 (33%), Gaps = 41/356 (11%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPP---PPPPGPALLPRRLRELRGKEVGL 261
PGP+ G +P G P A P LP PP P PPGP+ P GK+
Sbjct: 854 PGPQGVKGERGSPGG-PGAAGFPGARGLPGPPGSNGNPGPPGPSGSP-------GKDG-- 903
Query: 262 RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-PGSFGA-GL----G 315
P G T SP + AG + A LG G GA GL G
Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963
Query: 316 AQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG 375
GPR S V S A LS ERG PG PGL G PG P G
Sbjct: 964 MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGL---PGLAGTAGEPGRDGNPGSDG 1020
Query: 376 RGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQA- 434
D S DR P A A + G E PA PA +P A
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 435 ------PRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL--------CVLQPFPARSRG 480
P+ P + RG A R P PG G + P PA RG
Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140
Query: 481 ----LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVC 532
G P + G +G PG E GS + G PP P AP C
Sbjct: 1141 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC 1196
Score = 51.6 bits (122), Expect = 2e-06
Identities = 104/420 (24%), Positives = 123/420 (29%), Gaps = 60/420 (14%)
Query: 117 GMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCG 176
G+ G G GP + G P A P L G L P + G
Sbjct: 693 GLRGGAGPPGPEGGKGAAGPPGPPGAAGTP--------GLQGMPGERGGLGSPGPKGDKG 744
Query: 177 ARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPP 236
A G + RG + GP + G PGLP +A P P
Sbjct: 745 EPGG-PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS---PGER 800
Query: 237 PPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGS 296
PPGPA P + G+ G +G R A + G
Sbjct: 801 GETGPPGPAGFPGAPGQ-NGEPGG------------------KGERGAPGEKGEGGPPGV 841
Query: 297 ALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP-ERGSPGRPAFLRS 355
A GP G GP+ E GS G A P RG PG P +
Sbjct: 842 A--------GPPGGSGPAGPPGPQGVKGE----RGSPGGPGAAGFPGARGLPGPPGSNGN 889
Query: 356 PGLCGPGPVPGGLSVPTPCGRGAGDFS---EADLADRAFPVRGAGPIA-GRRRRRGWTFA 411
PG GP PG P P G S D P P A G G
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949
Query: 412 AALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL 471
A + PP P P+ + E+ P G + P P G GL
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP---PGPQGLPGLAGT 1006
Query: 472 QPFPARSRGLGVPSQQGPTGSPGCR-DRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
P R G G GSPG + DR GA G PP P PA
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP--------GHPGPPGPVGPA 1058
Score = 51.2 bits (121), Expect = 2e-06
Identities = 100/359 (27%), Positives = 118/359 (32%), Gaps = 66/359 (18%)
Query: 205 PGPRRGGGLTSAP--PGLPPLASPP--PFWELPRPPPPPP----PPGPALLPRRL-RELR 255
PGP G + P PG P PP P P PP PP P GPA R R
Sbjct: 179 PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGR 238
Query: 256 GKEVGLR--PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAG 313
E GL P +G P ++ G R + E G+ L N L PG GA
Sbjct: 239 PGERGLPGPPGIKGPAGIPGFPGMK-GHRGFDGRNGEKGETGAPGLKGENGL-PGENGAP 296
Query: 314 LGAQGPRSST-----PECPVVNGSEWGLAAPLSPER----GSPGRPAFLRSPGLCG---- 360
G GPR + P P G+ A S + G PG F SPG G
Sbjct: 297 -GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGP 355
Query: 361 ---------------PGPV--PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRR 403
PGP G P P G + ++ P GA + G R
Sbjct: 356 AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIP--GAPGLMGAR 413
Query: 404 RR---RGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLP 460
G A LR GA P A PR E P + G P
Sbjct: 414 GPPGPAGANGAPGLRGGAGE---PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470
Query: 461 AAPGFSGLCVLQPFPARSRGL----------GVPSQQGPTGSPGCRDRASAPRAGAEAG 509
PG +GL P A RG G+P ++GP G G A A E G
Sbjct: 471 GEPGANGL----PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525
Score = 51.2 bits (121), Expect = 2e-06
Identities = 83/322 (25%), Positives = 99/322 (30%), Gaps = 73/322 (22%)
Query: 205 PGPRRGGGLT--SAPPG------LPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRG 256
PGP GG + PPG LP PP P P P G P G
Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG------G 673
Query: 257 KEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 316
K P RG +P LR G+ GP G GA
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGA------------------------GPPGPEGGKGA 709
Query: 317 QGP-----RSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
GP + TP + G GL +P ++G PG P PG GP G +
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------------RK 416
P P G+ GD E A + G G R G A +
Sbjct: 770 PGPAGQ-PGDKGEGG-APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827
Query: 417 GAPREQ----PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ 472
GAP E+ PP P P G R P PG +G +
Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPP---------GPQGVKGERGSPGGPGAAGFPGAR 878
Query: 473 PFPARSRGLGVPSQQGPTGSPG 494
P G P GP+GSPG
Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPG 900
Score = 50.4 bits (119), Expect = 4e-06
Identities = 87/308 (28%), Positives = 102/308 (33%), Gaps = 57/308 (18%)
Query: 205 PGPR--RGGGLTSAPPGLPPLASP---PPFWELPRPPPPPPPPGPALLPRRLRELRGKEV 259
PGP RG PGLP A P PP PPG A P
Sbjct: 296 PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGS--------- 346
Query: 260 GLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGP 319
P +G SP GS A R PG G GAQGP
Sbjct: 347 ---PGAKGEVGPAGSP----GSNGAPGQRGE----------------PGPQGHA-GAQGP 382
Query: 320 RSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS---PGLCGPGPVPG---GLSVPTP 373
P P +NGS G + P G PG P + + PG G PG G P
Sbjct: 383 ----PGPPGINGSPGG-KGEMGPA-GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436
Query: 374 CGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFA-----AALRKGAPREQPPASP 427
G + + P V GA G+ G A AA +GAP + PA P
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496
Query: 428 AASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQ 486
P + A E+ P RG A +P PG G+ P G P
Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556
Query: 487 QGPTGSPG 494
QG +G PG
Sbjct: 557 QGESGRPG 564
Score = 47.8 bits (112), Expect = 3e-05
Identities = 115/460 (25%), Positives = 133/460 (28%), Gaps = 61/460 (13%)
Query: 70 PAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPA--GMAAGTGRSGP 127
P A A + G++ Q GP A P A A P G G GP
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373
Query: 128 GSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGA 187
G P +P +G A A GP GA GGA
Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGP--AGANGAPGLRGGA 431
Query: 188 SSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALL 247
+ G+N A GP RG + PG+P P PG L
Sbjct: 432 G----EPGKNGAKGEPGPRGERG---EAGIPGVPGAKGEDG------KDGSPGEPGANGL 478
Query: 248 PRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 307
P E RG P P RG+ R E G + GP
Sbjct: 479 PGAAGE-RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPG----GP 533
Query: 308 GSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPER-----------------GSPGRP 350
G G GP S P + E G P P G+PG+
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 351 AFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF 410
PG GP PG P G D D P GP G + G T
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP----GP-QGLQGLPG-TG 647
Query: 411 AAALRKGAPREQPPASPAASP----------CQAPRAPEKETEAPRLRGRATAVAPRP-- 458
G P E P A +P R P AP LRG A P
Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707
Query: 459 ----LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
P PG +G LQ P GLG P +G G PG
Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG 747
Score = 45.8 bits (107), Expect = 1e-04
Identities = 123/491 (25%), Positives = 153/491 (31%), Gaps = 68/491 (13%)
Query: 63 LRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGT 122
L + PP A G + + G K P PR +R A G+
Sbjct: 409 LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG-EPGPRGERGE------AGIPGVPGAK 461
Query: 123 GRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYA 182
G G GS +P P AA GA F + G + G R
Sbjct: 462 GEDGKD------GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE--KGPAGERGAPG 513
Query: 183 AAG--GASSRRRQRGRNPALIVRGPGPRRGGGLTSAP--PGLPPLASPPPFWELPRPPPP 238
AG GA+ + G + GPG R G+ +P PG PP P P
Sbjct: 514 PAGPRGAAGEPGRDG-----VPGGPGMR---GMPGSPGGPGSDGKPGPPGSQGESGRPGP 565
Query: 239 PPPPGPALLPRRL--------------RELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRA 284
P P GP P + RG G P+ P G
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP 625
Query: 285 GNHRVREIEFGSALLAAL-NTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPE 343
G + G L L T GP G GP+ P G + AP
Sbjct: 626 GGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG-APGAPGGKGDAGAP---- 680
Query: 344 RGSPGRPAFLRSPGLCG----PGPVPG-GLSVPTPCGRGAGDFSEADLADRAFPVRGAGP 398
G G P +PGL G PGP G G + P AG + + GP
Sbjct: 681 -GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739
Query: 399 IAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPR 457
+ G K PR P P P A + +K E AP L G A PR
Sbjct: 740 KGDKGEPGGPGADGVPGKDGPRG--PTGPIGPPGPAGQPGDKGEGGAPGLPGIA---GPR 794
Query: 458 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPR-AGAEAGSMETFLR 516
P G +G FP G P +G G+PG + P AG GS
Sbjct: 795 GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGS------ 848
Query: 517 NGGLYPPPSPR 527
G PP P+
Sbjct: 849 --GPAGPPGPQ 857
Score = 42.0 bits (97), Expect = 0.001
Identities = 69/250 (27%), Positives = 80/250 (32%), Gaps = 48/250 (19%)
Query: 313 GLGAQGPRSST--PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPV---PGG 367
G G QGP+ P P NG P SP GSPG P S C GP P
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSP--GSPGPPGICES---CPTGPQNYSPQY 155
Query: 368 LSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR--KGAPREQPPA 425
S G G A A P GP G G + + G P + P+
Sbjct: 156 DSYDVKSGVAVGGL--AGYPGPAGPPGPPGP-PGTSGHPGSPGSPGYQGPPGEPGQAGPS 212
Query: 426 SPAASP-CQAPRAPE-KETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS--RGL 481
P P P P K+ E+ GR R LP PG G + FP RG
Sbjct: 213 GPPGPPGAIGPSGPAGKDGES----GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268
Query: 482 -------------------------GVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLR 516
G P GP G+PG R R P A G+
Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328
Query: 517 NGGLYPPPSP 526
+G PP P
Sbjct: 329 DGQPGPPGPP 338
Score = 41.2 bits (95), Expect = 0.002
Identities = 94/356 (26%), Positives = 105/356 (29%), Gaps = 45/356 (12%)
Query: 186 GASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPA 245
GA R + G A RG RG PPG P A P P GPA
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG------FPGSPGAKGEVGPA 356
Query: 246 LLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRA-GNHRVREIEFGSALLAALNT 304
P G+ P+ P GS G I L+ A
Sbjct: 357 GSPGS-NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415
Query: 305 LGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPG 362
GP GA GA G R E P NG++ G P E G PG P G G
Sbjct: 416 PGPA--GAN-GAPGLRGGAGE-PGKNGAK-GEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470
Query: 363 PVPGGLSVPTPCG-RGAGDFSEADLADRAFP-------VRGAGPIAGRRRRRGWTFAAAL 414
PG +P G RGA F P RGA AG R G +
Sbjct: 471 GEPGANGLPGAAGERGAPGF-RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGV 529
Query: 415 RKGAPREQPPASPAASPCQA-PRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQP 473
G P SP P P + E+ GR P PG G
Sbjct: 530 PGGPGMRGMPGSPGGPGSDGKPGPPGSQGES----GRPGPPGPSGPRGQPGVMG------ 579
Query: 474 FPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
FP G P + G G PG P E G PP P P
Sbjct: 580 FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ----------GPPGPTGP 625
Score = 33.5 bits (75), Expect = 0.50
Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 21/118 (17%)
Query: 419 PREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARS 478
P + P + C P+ P T P +G P+ P PG P R+
Sbjct: 75 PNPEIPFGECCAVC--PQPPTAPTRPPNGQGPQ---GPKGDPGPPGI---------PGRN 120
Query: 479 RGLGVPSQQGPTGSPG----CRDRASAPRAGA---EAGSMETFLRNGGLYPPPSPRAP 529
G+P Q G GSPG C + P+ + ++ +++ + GGL P P P
Sbjct: 121 GDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 18/86 (20%)
Query: 306 GPGSFGAGLGAQGPRSST----PECPVVNGSEWGLAAPLSP--------ERGSPGRPAFL 353
GP +G+ GP P P G P+ P ERGS G P
Sbjct: 1122 GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHP 1181
Query: 354 RSPGLCGPGPVPGGLSVPTPCGRGAG 379
PG GP PG PC G G
Sbjct: 1182 GQPGPPGPPGAPG------PCCGGVG 1201
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 59.7 bits (143), Expect = 7e-09
Identities = 91/339 (26%), Positives = 110/339 (32%), Gaps = 79/339 (23%)
Query: 202 VRGP----GPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGK 257
V GP GPR G + PPG + P LP PP PP PPGP L
Sbjct: 110 VEGPKGDTGPRGPRG-PAGPPGRDGIPGQPG---LPGPPGPPGPPGPPGLGGNF------ 159
Query: 258 EVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQ 317
+P L G G ++ + GP GA
Sbjct: 160 ----------------APQLSYGYDEKSTG-------GISVPGPMGPSGPRGLPGPPGAP 196
Query: 318 GPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRG 377
GP+ + P E G + P+ P RG PG P G G PG P P G
Sbjct: 197 GPQGF--QGPPGEPGEPGASGPMGP-RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGA- 252
Query: 378 AGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRA 437
R P G + G + RG++ GA + PA P P
Sbjct: 253 -----------RGLP--GTAGLPGMKGHRGFSGL----DGAKGDAGPAGPKGEP------ 289
Query: 438 PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG----LGVPSQQGPTGSP 493
+P G + PR LP G G P PA +RG G GPTG
Sbjct: 290 -----GSPGENGAPGQMGPRGLPGERGRPG----APGPAGARGNDGATGAAGPPGPTGPA 340
Query: 494 GCRDRASAPRAGAEAGSMETFLRNG--GLYPPPSPRAPA 530
G A A EAG G G+ P P PA
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379
Score = 53.9 bits (128), Expect = 4e-07
Identities = 125/498 (25%), Positives = 152/498 (30%), Gaps = 87/498 (17%)
Query: 64 RSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTG 123
R PP A G + GP P + A +P G G
Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKP-GRPGERG 245
Query: 124 RSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAA 183
GP AR GL P A P G + A A +GP + G+ A
Sbjct: 246 PPGPQGAR-GL-----PGTAGLPGMKGHRGFSGLDGAKGDAGPAGP--KGEPGSPGENGA 297
Query: 184 AG--GASSRRRQRGRNPALIVRGPGPRRGG-GLTSA--PPGLPPLASPPPFWELPRPPPP 238
G G +RGR A GP RG G T A PPG A PP F
Sbjct: 298 PGQMGPRGLPGERGRPGA---PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE 354
Query: 239 PPPPGPALLPRRLRELRGKE--VGLR-----PRTRGWTTCVVSPNLRRGSRRAGNHRVRE 291
P GP RG E G+R P G +P G +
Sbjct: 355 AGPQGP----------RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404
Query: 292 IEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPA 351
I A GP G G GP+ ++ E P GS+ A +G PG
Sbjct: 405 IAGAPGFPGARGPSGPQGPG---GPPGPKGNSGE-PGAPGSKGDTGA-----KGEPGPVG 455
Query: 352 FLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFA 411
PG G G P P G R FP GA +AG + G
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP--GADGVAGPKGPAG---- 509
Query: 412 AALRKGAPREQPPASPAASPCQAPR-------------------APEKETEAPRLRGRAT 452
+G+P PA P SP +A R P+ +T P G+
Sbjct: 510 ---ERGSP---GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563
Query: 453 AVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSME 512
P P PG G + FP G P + G G PG EAG+
Sbjct: 564 RPGP---PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ- 619
Query: 513 TFLRNGGLYPPPSPRAPA 530
PP P PA
Sbjct: 620 ---------GPPGPAGPA 628
Score = 53.9 bits (128), Expect = 4e-07
Identities = 129/507 (25%), Positives = 157/507 (30%), Gaps = 139/507 (27%)
Query: 63 LRSSSAPPAATDAAHMSASTGTEVQMKRVGPK-----SWAPAPRRQRASSAQVRAARPAG 117
+R PP AA + + G + Q G + AP R S P G
Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428
Query: 118 MAAGTGRSG-PGS----------ARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAAL 166
+G G PGS +G+ PA R AR G T
Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR-------GEPGPTGLP 481
Query: 167 SGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASP 226
P R G+R F A G A + GP RG + P G P A
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPK-------------GPAGERGSPGPAGPKGSPGEAGR 528
Query: 227 PPFWELP-------RPPPPPP-----PPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVS 274
P LP P P P PPGPA ++ R G P RG +
Sbjct: 529 PGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG-----QDGRPGPPG-PPGARGQAGVMGF 582
Query: 275 PNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEW 334
P + + G R + +GP GAQGP P E
Sbjct: 583 PGPKGAAGEPGKAGERGVP------GPPGAVGPAGKDGEAGAQGPPG-----PAGPAGER 631
Query: 335 GLAAPLSPERGSPGRPAFLRSPGLCGPGP---------VPGGLSVPTPCG-RGAGDFSEA 384
G E+G G P F PG GP VPG L P P G RG
Sbjct: 632 G-------EQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG------- 677
Query: 385 DLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEA 444
+R FP G R +G PP P P A
Sbjct: 678 ---ERGFP--------GERGVQG---------------PPG---------PAGPRGANGA 702
Query: 445 PRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR-DRASAPR 503
P G A P APG G LQ G+P ++G G PG + DR A
Sbjct: 703 P---GNDGAKGDAGAPGAPGSQGAPGLQ---------GMPGERGAAGLPGPKGDRGDAGP 750
Query: 504 AGAEAGSMETFLRNGGLYPPPSPRAPA 530
GA+ + +R GL P P PA
Sbjct: 751 KGADGSPGKDGVR--GLTGPIGPPGPA 775
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/251 (29%), Positives = 85/251 (33%), Gaps = 54/251 (21%)
Query: 315 GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPC 374
G +GP+ T G P P G PGR PGL GP PG P
Sbjct: 109 GVEGPKGDT-----------GPRGPRGPA-GPPGRDGIPGQPGLPGPPGPPGPPGPPGLG 156
Query: 375 GRGAGDFSEADLADRAFPVRGAGPI--AGRRRRRGWTFAAALR--KGAPREQPPASPAAS 430
G A S + GP+ +G R G A + +G P E P P AS
Sbjct: 157 GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGE--PGEPGAS 214
Query: 431 PCQAPRAPE-------KETEA-----PRLRGRATAVAPRPLPAAPGFSGLCVLQPF---- 474
PR P + EA P RG R LP G G+ + F
Sbjct: 215 GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274
Query: 475 -------PARSRGL-------GVPSQQGPTGSPGCRDRASAP-RAGAEAGSMETFLRNGG 519
PA +G G P Q GP G PG R R AP AGA T G
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT-----G 329
Query: 520 LYPPPSPRAPA 530
PP P PA
Sbjct: 330 AAGPPGPTGPA 340
Score = 48.9 bits (115), Expect = 1e-05
Identities = 122/470 (25%), Positives = 143/470 (30%), Gaps = 84/470 (17%)
Query: 92 GPKSWAPAPRRQ--RASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAA 149
GPK +P + R + + PAG G SGP G+ P P
Sbjct: 749 GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808
Query: 150 RALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRR 209
G A G A A P + G AG P V PG +
Sbjct: 809 ---GPA--GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863
Query: 210 GGGLTSAPPGLPPLASPPPFWELPRPPP-----PPPPPGPALLPRRLRELRGKEVGLRPR 264
G ++ PPG P + P P PP PPGPA GKE G PR
Sbjct: 864 ARG-SAGPPGATGF--PGAAGRVGPPGPSGNAGPPGPPGPA----------GKEGGKGPR 910
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSS-- 322
P R G + GP GA GP +
Sbjct: 911 GE------TGPAGRPGE-----------------VGPPGPPGPAGEKGSPGADGPAGAPG 947
Query: 323 TPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG----RG 377
TP + G + P ERG PG P PG GP G P P G G
Sbjct: 948 TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007
Query: 378 AGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--RKGAPREQPPASPAASPCQ-- 433
S + A A G G + RG T A GAP P PA
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG 1067
Query: 434 --APRAPEKETEAPRLRGRATAVAP------------RPLPAAPGFSGLCVLQPFPARSR 479
P P RG A P R + GFSGL P P
Sbjct: 1068 ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGL-QGPPGPP--- 1123
Query: 480 GLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNG--GLYPPPSPR 527
G P +QGP+G+ G P AG+ NG G PP PR
Sbjct: 1124 --GSPGEQGPSGASGPAGPRGPP---GSAGAPGKDGLNGLPGPIGPPGPR 1168
Score = 46.2 bits (108), Expect = 8e-05
Identities = 117/469 (24%), Positives = 145/469 (30%), Gaps = 90/469 (19%)
Query: 113 ARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGA-------------ALFGR 159
A P G A G GP + G P A P A G+ G+
Sbjct: 502 AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ 561
Query: 160 AVHTAALSGPHCRLRCGARAFYAAAGGASS--RRRQRGRNPALIVRGPGPRRGGGLTSAP 217
P R + G F G A + +RG GP + G P
Sbjct: 562 DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP 621
Query: 218 PG-LPPL--------ASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGW 268
PG P A P F LP P PP G + E G+ P G
Sbjct: 622 PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG-----------KPGEQGV-PGDLG- 668
Query: 269 TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE-CP 327
P+ RG R R + G A N PG+ GA A P + + P
Sbjct: 669 ---APGPSGARGERGFPGERGVQGPPGPAGPRGANG-APGNDGAKGDAGAPGAPGSQGAP 724
Query: 328 VVNG--SEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSE 383
+ G E G A P +RG G SPG G + G + P P G GD E
Sbjct: 725 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG-APGDKGE 783
Query: 384 ADLADRAFPVRGAGPIAGRRRRRGWTFAAALR-----------KGAPREQPPASPAASPC 432
+ + A P GA G R G A KG P + A P
Sbjct: 784 SGPSGPAGPT-GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG 842
Query: 433 QA----PRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRG------ 480
A P P AP +G + P P A GF G V P P+ + G
Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGP---PGATGFPGAAGRVGPPGPSGNAGPPGPPG 899
Query: 481 ----------------LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMET 513
G P + GP G PG +P A AG+ T
Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGT 948
Score = 44.3 bits (103), Expect = 3e-04
Identities = 74/246 (30%), Positives = 83/246 (33%), Gaps = 46/246 (18%)
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCG----P 361
PG GA A P + P P G + AP RGS G P PG G P
Sbjct: 829 PGDAGAKGDAGPPGPAGPAGPP--GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886
Query: 362 GPV--PGGLSVPTPCGR--GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKG 417
GP G P P G+ G G E A R V GP A KG
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG-----------PAGEKG 935
Query: 418 APREQPPASPAASPCQAPRAPEKETEA-PRLRGRATAVAPRPLPAAPGFSGLCVLQPFPA 476
+P PA +P A ++ P RG R P PG SG Q
Sbjct: 936 SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE------RGFPGLPGPSGEPGKQGPSG 989
Query: 477 RSRGLGVPSQQGP---TGSPGCRDRASAPRA----------GAEAGSMETFLRNGGLYPP 523
S G P GP G PG R AP A GA+ ET G PP
Sbjct: 990 ASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET----GPAGPP 1045
Query: 524 PSPRAP 529
+P AP
Sbjct: 1046 GAPGAP 1051
Score = 34.3 bits (77), Expect = 0.30
Identities = 85/328 (25%), Positives = 98/328 (29%), Gaps = 37/328 (11%)
Query: 64 RSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTG 123
R S+ PP AT + G GP P P + PAG G
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG-PPGPAGKEGGKGPRGETGPAGRPGEVG 923
Query: 124 RSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAA 183
GP GS A AP G A V L G G R F
Sbjct: 924 PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV---GLPGQR-----GERGFPGL 975
Query: 184 AGGASSRRRQRGRNPALIVRGP-GPRRGGGLTSAP-----PGLPPLASPPPFWELPR--- 234
G + +Q G + A RGP GP GL P G P P P
Sbjct: 976 PGPSGEPGKQ-GPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034
Query: 235 ------PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHR 288
P PP PG P + GK V P RG R
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPA-GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR 1093
Query: 289 VREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPG 348
+ E G + G F G GP P P G G + P P RG PG
Sbjct: 1094 GDKGETGEQGDRGIK--GHRGFSGLQGPPGP----PGSPGEQGPS-GASGPAGP-RGPPG 1145
Query: 349 RPAFLRSPGLCGPGPVPGGLSVPTPCGR 376
+PG G +PG + P P GR
Sbjct: 1146 SAG---APGKDGLNGLPGPIGPPGPRGR 1170
Score = 34.3 bits (77), Expect = 0.30
Identities = 47/191 (24%), Positives = 58/191 (30%), Gaps = 33/191 (17%)
Query: 70 PAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPG- 128
P A + S G + GP AP A PAG + G +GP
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP----VGPAGKSGDRGETGPAG 1073
Query: 129 -SARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGA 187
+ +G PA PR + R + G R F G
Sbjct: 1074 PAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK-------------GHRGFSGLQGPP 1120
Query: 188 SSRRRQRGRNPALIVRGPGPRRGGGLTSAPP-----GLP-PLASPPPFWEL--------P 233
+ P+ GPR G AP GLP P+ P P P
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180
Query: 234 RPPPPPPPPGP 244
PP PP PPGP
Sbjct: 1181 GPPGPPGPPGP 1191
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 59.7 bits (143), Expect = 7e-09
Identities = 85/317 (26%), Positives = 115/317 (36%), Gaps = 43/317 (13%)
Query: 62 LLRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAG 121
L+ + APPAA S G+ + + P P A A+PAG AA
Sbjct: 114 LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP-------APAGPAKPAGPAAL 166
Query: 122 TGRSGPGSAR-LGLGSGWDPARAVAPRAARAL-GAALFGRAVHTAALSGPHCRLRCGARA 179
R+GPG G G G P + P AA+ L G+A + H AA P L
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA---PAVSL------ 217
Query: 180 FYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPP 239
G A+ + P +++ P P G AP P A+P P P PPP
Sbjct: 218 --VNNGPAALLPLPKPAAPGTVIQTP-PFVGAAAPPAPAAPSPPAAPAP--AAPAAAPPP 272
Query: 240 PPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALL 299
PPP PA L R G V P + AG G
Sbjct: 273 PPPAPATLARPPGHPAGPPTA--------APAVPPPAAAQNGGSAGAAPAPAPAAGGP-A 323
Query: 300 AALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 359
GPG+ A A G ++ +P+ V AAP + + + PA + +
Sbjct: 324 GVSGQPGPGA-AAAAPAPGVKAESPKRVV-------QAAPPAAQTLAASGPASTAASMVI 375
Query: 360 GP---GPVPGGLSVPTP 373
GP G +P +VP P
Sbjct: 376 GPTMQGALPSPAAVPPP 392
Score = 52.4 bits (124), Expect = 1e-06
Identities = 103/357 (28%), Positives = 119/357 (33%), Gaps = 54/357 (15%)
Query: 164 AALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPL 223
AA + H L AAA GA G GP G +AP PP
Sbjct: 34 AASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEP-PPA 92
Query: 224 ASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWT-TCVVSPN---LRR 279
P P+ P PP P P L+P K LRP G +C P +
Sbjct: 93 GRARPGGGGPQRPGPPSPRRP-LVPAGPAPPAAK---LRPPPEGSAGSCAPVPAAAAVAA 148
Query: 280 GSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP 339
G A + G A LAA GPG G G G GP P P + G AA
Sbjct: 149 GPEPAPAGPAKPA--GPAALAARAGPGPGP-GPGPGP-GPGPGKPAGPGAAQTLNGSAAL 204
Query: 340 L-SPERGSPGRPAFLRSPGLCGPGPVPG--GLSVPTPCGRGAGDFSEADLADRAFPVRGA 396
L S +P P P P P G + TP GA A P A
Sbjct: 205 LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA-----------AAPPAPA 253
Query: 397 GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAP-RLRGRATAVA 455
P P PA+PAA+P P AP P G TA
Sbjct: 254 AP------------------SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295
Query: 456 PRPLPAAPGFSGLCVLQPFPARSRG--LGVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
P PAA G P PA + G GV Q GP + A+AP G +A S
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA------AAAPAPGVKAES 346
Score = 35.0 bits (79), Expect = 0.17
Identities = 54/200 (27%), Positives = 66/200 (33%), Gaps = 39/200 (19%)
Query: 70 PAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGS 129
PAA A+ GT +Q + PAP A+ + A PA AA P
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAP----AAPSPPAAPAPAAPAAAPPPPPPAP 277
Query: 130 ARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASS 189
A L G A A AA G + A P AAGG +
Sbjct: 278 ATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP-------------AAGGPAG 324
Query: 190 RRRQRGRNPALIVRGPG-----PRRGGGLTSAPPGLPPLASPPPF-------------WE 231
Q G A PG P+R + +APP LA+ P
Sbjct: 325 VSGQPGPGAAAAAPAPGVKAESPKRV--VQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Query: 232 LPRPP--PPPPPPGPALLPR 249
LP P PPP P P LP+
Sbjct: 383 LPSPAAVPPPAPGTPTGLPK 402
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 59.3 bits (142), Expect = 9e-09
Identities = 100/396 (25%), Positives = 120/396 (30%), Gaps = 69/396 (17%)
Query: 115 PAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
P G+ GR+GP A G+ P A P G F A +GP
Sbjct: 325 PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP----- 379
Query: 175 CGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPR 234
GAR A G RG GP G T PG A P P
Sbjct: 380 TGARGPEGAQG-------PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432
Query: 235 PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEF 294
P P PPGP +G L P+ + + +G + E
Sbjct: 433 FPGPRGPPGP----------QGATGPLGPKGQTGEPGIAGFKGEQGPKG---------EP 473
Query: 295 GSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAF 352
G A GP G +G R + E G P+ P ERG+PG F
Sbjct: 474 GPA--------GPQGAPGPAGEEGKRGAR--------GEPGGVGPIGPPGERGAPGNRGF 517
Query: 353 LRSPGLCGPGPVPG-----GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRG 407
GL GP PG GL+ P G E L GA + GR G
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-------GARGLTGRPGDAG 570
Query: 408 WTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAAPGFS 466
GAP E P + P+ G + LP APG
Sbjct: 571 -PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629
Query: 467 GLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAP 502
GL P + G GP G G R AP
Sbjct: 630 GL------PGKDGETGAAGPPGPAGPAGERGEQGAP 659
Score = 47.0 bits (110), Expect = 4e-05
Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 22/220 (10%)
Query: 327 PVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPG--GLSVPTPCGRGAGDFSE 383
P ++G++ AP + E GSPG SPG GP +PG G + P G+ +
Sbjct: 293 PGLDGAKGEAGAPGVKGESGSPGENG---SPGPMGPRGLPGERGRTGPAGAAGARGNDGQ 349
Query: 384 ADLADRAFPVRGAG----PIAGRRRRRGWTFAAALRKGA--PREQPPASPAASPCQAPRA 437
A PV AG P A + A +GA PR +P + P A
Sbjct: 350 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409
Query: 438 PEKE--------TEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGP 489
P + AP + G PR P G +G + G +QGP
Sbjct: 410 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 469
Query: 490 TGSPGCRDRASAPRAGAEAGSMETFLRNGGLYP--PPSPR 527
G PG AP E G GG+ P PP R
Sbjct: 470 KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509
Score = 47.0 bits (110), Expect = 4e-05
Identities = 68/239 (28%), Positives = 84/239 (35%), Gaps = 37/239 (15%)
Query: 315 GAQGPRSST--PEC------PVVNGSEWGLAAPLSPE--------RGSPGRPAFLRSPGL 358
GAQGP +T P P NG+ G P P RG G P PGL
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNP-GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946
Query: 359 CGPGPVPGGLSVPTPCGRGA--GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 416
GP PG P G G LA + RG + G+R RG+
Sbjct: 947 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ----RGIVGLPGQRGERGFPGLPG-PS 1001
Query: 417 GAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAA---PGFSGLCVLQP 473
G P +Q +P AS + P P P L G A P A PG G ++
Sbjct: 1002 GEPGKQ--GAPGASGDRGPPGP---VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056
Query: 474 FPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNG-----GLYPPPSPR 527
+ +G P GP GSPG EAG+ +G G+ P PR
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115
Score = 46.6 bits (109), Expect = 6e-05
Identities = 112/445 (25%), Positives = 141/445 (31%), Gaps = 52/445 (11%)
Query: 70 PAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGS 129
P AA ++ G + GP+ AP R + + PAG G GP
Sbjct: 752 PGERGAAGIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810
Query: 130 ARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAG--GA 187
G+ P G A P + GA+ AG G
Sbjct: 811 PAGSAGARGAPGERGETGPPGPAGFA-----------GPPGADGQPGAKGEQGEAGQKGD 859
Query: 188 SSRRRQRGRNPALIVRGP----GPRRGGGLTSAP-----PGLPPLASPPPFWELPRPPPP 238
+ +G + A +GP GP+ G P PG PP P PP P
Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919
Query: 239 PPPPGPALLPRRLRELRGKEVGL-RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSA 297
P P G P+ R G P +G P +G E G
Sbjct: 920 PGPSGKDG-PKGARGDSGPPGRAGEPGLQG----PAGPPGEKGEPGDDGPSGAEGPPGPQ 974
Query: 298 LLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSP 356
LA + GL Q P P +G AP S +RG PG + P
Sbjct: 975 GLAGQRGI------VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP---VGPP 1025
Query: 357 GLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR----AFPVRGAGPIAGRRRRRGWTFAA 412
GL GP PG P G D + DR A GA G G T
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085
Query: 413 ALRKGAPREQP--PASPA-ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
R A + P P+ PA A Q P+ P + +G A R L GF+GL
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGLQ 1139
Query: 470 VLQPFPARSRGLGVPSQQGPTGSPG 494
L P S G GP+G G
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRG 1164
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 46/221 (20%)
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVP 365
PG G G QGPR + E+G+PG PG G PGP P
Sbjct: 122 PGPQGPA-GEQGPRGDRGD---------------KGEKGAPGPRGRDGEPGTPGNPGP-P 164
Query: 366 GGLSVPTPCGRG-------AGDFSE----ADLADRAFPVRGAGPI-----AGRRRRRGWT 409
G P P G G AG F E A L P+ GP AG +G+
Sbjct: 165 GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF- 223
Query: 410 FAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
+G P E P P S PR P P G A PG G
Sbjct: 224 ------QGNPGE--PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA- 274
Query: 470 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
+ FP GV +G G G + A AP E+GS
Sbjct: 275 --RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/246 (28%), Positives = 84/246 (34%), Gaps = 45/246 (18%)
Query: 307 PGSFGA-GLGAQGPRSSTPECPVVNG-----SEWGLAAPLSP--------ERGSPGRPAF 352
PG GA G + P P + G E G A P P E+G+PG F
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 353 LRSPGLCGP---GPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGW 408
PG GP G PG VP G +R FP RG+ G + RG
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVP---GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 721
Query: 409 TFA--------AALRKGAPREQPPASPAASPCQAPRAP------------EKETE-APRL 447
A+ G P Q P P + A EK E AP
Sbjct: 722 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 781
Query: 448 RGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRA 504
G P P G +G V P PA S G G P ++G TG PG A P A
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841
Query: 505 GAEAGS 510
+ G+
Sbjct: 842 DGQPGA 847
Score = 41.6 bits (96), Expect = 0.002
Identities = 110/435 (25%), Positives = 146/435 (33%), Gaps = 63/435 (14%)
Query: 116 AGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRC 175
AG G GP G+ DP R P A G L GR +GP ++
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG--LTGRPGD----AGPQGKV-- 575
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAP-----PGLPPLASPPPFW 230
G G Q R ++ PGP+ G PG P L P
Sbjct: 576 GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635
Query: 231 ELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVR 290
PP P GPA RG++ P G+ P + G+ V
Sbjct: 636 GETGAAGPPGPAGPA-------GERGEQGA--PGPSGFQGLPGPPGPPGEGGKPGDQGVP 686
Query: 291 EIEFGSALLAALNTLG-PGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSP 347
L+ G PG G+ G QGPR P P +G + G + P P G+
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-LPGTPGTDGPK-GASGPAGPP-GAQ 743
Query: 348 GRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAF--PVRGAGPIAGRRRR 405
G P PG G + G G + + R P+ GP AG
Sbjct: 744 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP-AGANGE 802
Query: 406 RGWT-----FAAALRKGAPREQP---PASPA--ASPCQA---PRAPEKETEAPRLRGRAT 452
+G +A +GAP E+ P PA A P A P A ++ EA + +G A
Sbjct: 803 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ-KGDAG 861
Query: 453 AVAPRPLPAAPGFSGLC-VLQP--------------FPARSRGLGVPSQQG---PTGSPG 494
A P+ APG G V P FP + +G P G P G PG
Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921
Query: 495 CRDRASAPRAGAEAG 509
+ A ++G
Sbjct: 922 PSGKDGPKGARGDSG 936
Score = 40.4 bits (93), Expect = 0.004
Identities = 99/416 (23%), Positives = 129/416 (31%), Gaps = 57/416 (13%)
Query: 64 RSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTG 123
R + PP AT + G GP P P + + P G A G
Sbjct: 887 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG-PPGPSGKDGPKGARGDSGPPGRAGEPG 945
Query: 124 RSGPGSARLGLGSGWD--PARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFY 181
GP G D P+ A P + L R + L G G R F
Sbjct: 946 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ---RGI--VGLPGQR-----GERGFP 995
Query: 182 AAAGGASSRRRQRGRNPALIVRGP-GPRRGGGLTSAPPGLP-----PLASPPPFWE---- 231
G + +Q G A RGP GP GLT P G P P A PP +
Sbjct: 996 GLPGPSGEPGKQ-GAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPGADGPPGRDGAAG 1053
Query: 232 ------------LPRPPPPPPPPGPALLPRRL--RELRGKEVGLRPRTRGWTTCVVSPNL 277
P P PP PGPA + R G + + P + P
Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1113
Query: 278 RRGSR-RAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST-------PECPVV 329
RG + AG R ++ GP GA GP + P P
Sbjct: 1114 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173
Query: 330 NGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR 389
G+ P+ P PG G GP PG P P G G + A L R
Sbjct: 1174 KDGANGIPGPIGP----PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR 1229
Query: 390 AFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAP 445
+G P+ R + A LR+ + ++ R+PE + P
Sbjct: 1230 E---KGPDPLQYMRADQA---AGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1279
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 59.3 bits (142), Expect = 9e-09
Identities = 100/396 (25%), Positives = 120/396 (30%), Gaps = 69/396 (17%)
Query: 115 PAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
P G+ GR+GP A G+ P A P G F A +GP
Sbjct: 256 PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP----- 310
Query: 175 CGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPR 234
GAR A G RG GP G T PG A P P
Sbjct: 311 TGARGPEGAQG-------PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 363
Query: 235 PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEF 294
P P PPGP +G L P+ + + +G + E
Sbjct: 364 FPGPRGPPGP----------QGATGPLGPKGQTGEPGIAGFKGEQGPKG---------EP 404
Query: 295 GSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAF 352
G A GP G +G R + E G P+ P ERG+PG F
Sbjct: 405 GPA--------GPQGAPGPAGEEGKRGAR--------GEPGGVGPIGPPGERGAPGNRGF 448
Query: 353 LRSPGLCGPGPVPG-----GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRG 407
GL GP PG GL+ P G E L GA + GR G
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-------GARGLTGRPGDAG 501
Query: 408 WTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAAPGFS 466
GAP E P + P+ G + LP APG
Sbjct: 502 -PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560
Query: 467 GLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAP 502
GL P + G GP G G R AP
Sbjct: 561 GL------PGKDGETGAAGPPGPAGPAGERGEQGAP 590
Score = 47.0 bits (110), Expect = 4e-05
Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 22/220 (10%)
Query: 327 PVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPG--GLSVPTPCGRGAGDFSE 383
P ++G++ AP + E GSPG SPG GP +PG G + P G+ +
Sbjct: 224 PGLDGAKGEAGAPGVKGESGSPGENG---SPGPMGPRGLPGERGRTGPAGAAGARGNDGQ 280
Query: 384 ADLADRAFPVRGAG----PIAGRRRRRGWTFAAALRKGA--PREQPPASPAASPCQAPRA 437
A PV AG P A + A +GA PR +P + P A
Sbjct: 281 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340
Query: 438 PEKE--------TEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGP 489
P + AP + G PR P G +G + G +QGP
Sbjct: 341 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP 400
Query: 490 TGSPGCRDRASAPRAGAEAGSMETFLRNGGLYP--PPSPR 527
G PG AP E G GG+ P PP R
Sbjct: 401 KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440
Score = 47.0 bits (110), Expect = 4e-05
Identities = 68/239 (28%), Positives = 84/239 (35%), Gaps = 37/239 (15%)
Query: 315 GAQGPRSST--PEC------PVVNGSEWGLAAPLSPE--------RGSPGRPAFLRSPGL 358
GAQGP +T P P NG+ G P P RG G P PGL
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNP-GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877
Query: 359 CGPGPVPGGLSVPTPCGRGA--GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 416
GP PG P G G LA + RG + G+R RG+
Sbjct: 878 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ----RGIVGLPGQRGERGFPGLPG-PS 932
Query: 417 GAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAA---PGFSGLCVLQP 473
G P +Q +P AS + P P P L G A P A PG G ++
Sbjct: 933 GEPGKQ--GAPGASGDRGPPGP---VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987
Query: 474 FPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNG-----GLYPPPSPR 527
+ +G P GP GSPG EAG+ +G G+ P PR
Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046
Score = 46.6 bits (109), Expect = 6e-05
Identities = 112/445 (25%), Positives = 141/445 (31%), Gaps = 52/445 (11%)
Query: 70 PAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGS 129
P AA ++ G + GP+ AP R + + PAG G GP
Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741
Query: 130 ARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAG--GA 187
G+ P G A P + GA+ AG G
Sbjct: 742 PAGSAGARGAPGERGETGPPGPAGFA-----------GPPGADGQPGAKGEQGEAGQKGD 790
Query: 188 SSRRRQRGRNPALIVRGP----GPRRGGGLTSAP-----PGLPPLASPPPFWELPRPPPP 238
+ +G + A +GP GP+ G P PG PP P PP P
Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850
Query: 239 PPPPGPALLPRRLRELRGKEVGL-RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSA 297
P P G P+ R G P +G P +G E G
Sbjct: 851 PGPSGKDG-PKGARGDSGPPGRAGEPGLQG----PAGPPGEKGEPGDDGPSGAEGPPGPQ 905
Query: 298 LLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSP 356
LA + GL Q P P +G AP S +RG PG + P
Sbjct: 906 GLAGQRGI------VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP---VGPP 956
Query: 357 GLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR----AFPVRGAGPIAGRRRRRGWTFAA 412
GL GP PG P G D + DR A GA G G T
Sbjct: 957 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016
Query: 413 ALRKGAPREQP--PASPA-ASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
R A + P P+ PA A Q P+ P + +G A R L GF+GL
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGLQ 1070
Query: 470 VLQPFPARSRGLGVPSQQGPTGSPG 494
L P S G GP+G G
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRG 1095
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 46/221 (20%)
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVP 365
PG G G QGPR + E+G+PG PG G PGP P
Sbjct: 53 PGPQGPA-GEQGPRGDRGD---------------KGEKGAPGPRGRDGEPGTPGNPGP-P 95
Query: 366 GGLSVPTPCGRG-------AGDFSE----ADLADRAFPVRGAGPI-----AGRRRRRGWT 409
G P P G G AG F E A L P+ GP AG +G+
Sbjct: 96 GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGF- 154
Query: 410 FAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
+G P E P P S PR P P G A PG G
Sbjct: 155 ------QGNPGE--PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA- 205
Query: 470 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
+ FP GV +G G G + A AP E+GS
Sbjct: 206 --RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/246 (28%), Positives = 84/246 (34%), Gaps = 45/246 (18%)
Query: 307 PGSFGA-GLGAQGPRSSTPECPVVNG-----SEWGLAAPLSP--------ERGSPGRPAF 352
PG GA G + P P + G E G A P P E+G+PG F
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 353 LRSPGLCGP---GPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGW 408
PG GP G PG VP G +R FP RG+ G + RG
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVP---GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 652
Query: 409 TFA--------AALRKGAPREQPPASPAASPCQAPRAP------------EKETE-APRL 447
A+ G P Q P P + A EK E AP
Sbjct: 653 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 712
Query: 448 RGRATAVAPRPLPAAPGFSGLC--VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRA 504
G P P G +G V P PA S G G P ++G TG PG A P A
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772
Query: 505 GAEAGS 510
+ G+
Sbjct: 773 DGQPGA 778
Score = 41.6 bits (96), Expect = 0.002
Identities = 110/435 (25%), Positives = 146/435 (33%), Gaps = 63/435 (14%)
Query: 116 AGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRC 175
AG G GP G+ DP R P A G L GR +GP ++
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG--LTGRPGD----AGPQGKV-- 506
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAP-----PGLPPLASPPPFW 230
G G Q R ++ PGP+ G PG P L P
Sbjct: 507 GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566
Query: 231 ELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVR 290
PP P GPA RG++ P G+ P + G+ V
Sbjct: 567 GETGAAGPPGPAGPA-------GERGEQGA--PGPSGFQGLPGPPGPPGEGGKPGDQGVP 617
Query: 291 EIEFGSALLAALNTLG-PGSFGA--GLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSP 347
L+ G PG G+ G QGPR P P +G + G + P P G+
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-LPGTPGTDGPK-GASGPAGPP-GAQ 674
Query: 348 GRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAF--PVRGAGPIAGRRRR 405
G P PG G + G G + + R P+ GP AG
Sbjct: 675 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP-AGANGE 733
Query: 406 RGWT-----FAAALRKGAPREQP---PASPA--ASPCQA---PRAPEKETEAPRLRGRAT 452
+G +A +GAP E+ P PA A P A P A ++ EA + +G A
Sbjct: 734 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ-KGDAG 792
Query: 453 AVAPRPLPAAPGFSGLC-VLQP--------------FPARSRGLGVPSQQG---PTGSPG 494
A P+ APG G V P FP + +G P G P G PG
Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852
Query: 495 CRDRASAPRAGAEAG 509
+ A ++G
Sbjct: 853 PSGKDGPKGARGDSG 867
Score = 40.4 bits (93), Expect = 0.004
Identities = 99/416 (23%), Positives = 129/416 (31%), Gaps = 57/416 (13%)
Query: 64 RSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTG 123
R + PP AT + G GP P P + + P G A G
Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG-PPGPSGKDGPKGARGDSGPPGRAGEPG 876
Query: 124 RSGPGSARLGLGSGWD--PARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFY 181
GP G D P+ A P + L R + L G G R F
Sbjct: 877 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ---RGI--VGLPGQR-----GERGFP 926
Query: 182 AAAGGASSRRRQRGRNPALIVRGP-GPRRGGGLTSAPPGLP-----PLASPPPFWE---- 231
G + +Q G A RGP GP GLT P G P P A PP +
Sbjct: 927 GLPGPSGEPGKQ-GAPGASGDRGPPGPVGPPGLTG-PAGEPGREGSPGADGPPGRDGAAG 984
Query: 232 ------------LPRPPPPPPPPGPALLPRRL--RELRGKEVGLRPRTRGWTTCVVSPNL 277
P P PP PGPA + R G + + P + P
Sbjct: 985 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1044
Query: 278 RRGSR-RAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSST-------PECPVV 329
RG + AG R ++ GP GA GP + P P
Sbjct: 1045 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104
Query: 330 NGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADR 389
G+ P+ P PG G GP PG P P G G + A L R
Sbjct: 1105 KDGANGIPGPIGP----PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR 1160
Query: 390 AFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAP 445
+G P+ R + A LR+ + ++ R+PE + P
Sbjct: 1161 E---KGPDPLQYMRADQA---AGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1210
>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
sapiens]
Length = 398
Score = 57.0 bits (136), Expect = 4e-08
Identities = 107/362 (29%), Positives = 136/362 (37%), Gaps = 87/362 (24%)
Query: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSG-----PGSAR-LGLGSGWDPARAVAPRAAR 150
AP ++ R S A++ R AG GR PGS R LG PARA R
Sbjct: 72 APGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGF---PARAGQGRVQG 128
Query: 151 AL-GAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRR 209
A G L G SGP +R GA AAA Q G + + GPGP
Sbjct: 129 AAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAA------EHQLGAGFS-VRNGPGPP- 180
Query: 210 GGGLTSAPPG--LPPLASPPPFWELPRPPPPPPPPGPALLPR----RLRELRGKEVGLRP 263
L APPG L P P P++ PR PP PP L P R R + +RP
Sbjct: 181 -ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRP 239
Query: 264 RTRGWTTCVVSPNL-------RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 316
R R V++P L RGSR SA+L+ AGLG
Sbjct: 240 RLR-----VLTPPLALRCALPERGSRTPSTR--------SAVLSGR--------VAGLGT 278
Query: 317 QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGR 376
+ + TP +GS LS ER + AF + L P P S+P+P +
Sbjct: 279 E--LTLTPSSRRAHGSH-----ALSSERQAAPTRAFCSADPL--PRPPSFVPSLPSPQAQ 329
Query: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA-SPAASPCQAP 435
G+ R+ AAL +GAPR + P+ P +P P
Sbjct: 330 ------------------------GQAVRQPRLLRAALARGAPRGRTPSPRPGPAPALQP 365
Query: 436 RA 437
A
Sbjct: 366 YA 367
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 56.2 bits (134), Expect = 7e-08
Identities = 106/411 (25%), Positives = 132/411 (32%), Gaps = 102/411 (24%)
Query: 193 QRGRNPALIVRG----PGPRRGGGLTSA-------PPGLPPLASPPPFWELPRPPPPPPP 241
QRGR + RG PG G +A PPG+P P P P PP P
Sbjct: 622 QRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGP 681
Query: 242 PGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLR-----RGSRR-AGNHRVREIEFG 295
G L+ LRG EVGL P +G + P + +G R G +R +
Sbjct: 682 VG-------LQGLRG-EVGL-PGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGA 732
Query: 296 SALLAALNTLGPGSFGAGLGAQGPRSST-------PECPVVNGSEWGLAAPLSPER--GS 346
A +GP G +G + T P P + + GL P P+ G+
Sbjct: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT 792
Query: 347 PGRPAFLRSPGLCG----------------PGPVPGGLSVPTPCGRGAGDFSEADLADRA 390
PGRP PG G PGP PG + P P G G A L
Sbjct: 793 PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP-PGAMGPPGPPG-APGPAGPAGLPGHQ 850
Query: 391 FPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKE-------TE 443
+ GP G P + P P+ PR P E
Sbjct: 851 EVLNLQGP-----------------PGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPP 893
Query: 444 APRLRGRATAVAPRPLPAAP----------------GFSGLCVLQPFPARSRGL------ 481
L T ++ P P P G GL + S GL
Sbjct: 894 GSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPP 953
Query: 482 GVPSQQGP---TGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
G P QGP G PG P +E GS T +G PP P P
Sbjct: 954 GPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPP 1004
Score = 37.7 bits (86), Expect = 0.027
Identities = 40/151 (26%), Positives = 52/151 (34%), Gaps = 9/151 (5%)
Query: 344 RGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRR 403
RGSPG + SPG G PG +P P G + P GP+ G+R
Sbjct: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM-EGPM-GQR 623
Query: 404 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP 463
R G G P A+ P P + +G + + P+ P
Sbjct: 624 GREG-PMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPV 682
Query: 464 GFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
G GL P GV +GP G PG
Sbjct: 683 GLQGLRGEVGLP------GVKGDKGPMGPPG 707
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 56.2 bits (134), Expect = 7e-08
Identities = 114/483 (23%), Positives = 161/483 (33%), Gaps = 72/483 (14%)
Query: 69 PPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPG 128
PPAAT + + P + P+P+ A+ + A P + + + P
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 129 SARLGLGSGWDPARAV-APRAARAL-----GAALFGRAVHTAALSGPHCRLRCGARAFYA 182
+ G+ PA +P+ + A GA A + GP GA A
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Query: 183 AAG----GASSRRRQRGRNPALIVRGPGPRRGGGLTSAP----PGLPPLASPPPFWELPR 234
A G + +G P P+ GGL + P P P P P L
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPK--GGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 235 PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEF 294
PPP P PA P + + P TT +P +G + +
Sbjct: 1143 PPPKGAPTTPAATPPSPKG----GLATPPPKGAPTTPAATPPSPKGGLATPSPK------ 1192
Query: 295 GSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN--GSEWGLAAPLSPERGSPGRPAF 352
G+ A P S GL P+ + P P + GLA P SP +G+P PA
Sbjct: 1193 GAPTTPAAT---PPSPKGGLATPSPKGA-PTTPAATPPSPKGGLATP-SP-KGAPTTPA- 1245
Query: 353 LRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAA 412
P GG + P P G A A P G +A + A
Sbjct: 1246 ------ATPPSPKGGPATPPPKG--------APTPPAATPPSLKGGLATPPHKGAPNPAV 1291
Query: 413 ALR---KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
KG P PP P P +P+ P +G T A P P+ G L
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP-PSPKGTPTL- 1349
Query: 470 VLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP-RA 528
PA + PS +G +P ++ + P A + G PPSP R
Sbjct: 1350 -----PATT-----PSSKGGPTTPSSKEGPTPPAATPSH-------KGGPAMTPPSPKRG 1392
Query: 529 PAV 531
PA+
Sbjct: 1393 PAI 1395
Score = 52.8 bits (125), Expect = 8e-07
Identities = 88/368 (23%), Positives = 122/368 (33%), Gaps = 55/368 (14%)
Query: 198 PALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPAL-------LPRR 250
PAL + P++ T AP G+P SP P PP P GPA P
Sbjct: 909 PALSMTSSSPKKARA-TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 251 LRELRGKEVGLRPRTRGW-TTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGS 309
K P +G T +P +G + + G+ A+ P
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK------GAPTPPAVTPPSPKG 1021
Query: 310 FGAGL----GAQGPRSSTP--------ECPVVNGSEWGLAAPLSPERGSPGRPAF--LRS 355
A GA P ++TP P+ G+ AA L +G P P+ +
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 356 PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL- 414
P P GG + P+P G A + A P G +A + T AA
Sbjct: 1082 PPAATPPSPKGGPATPSPKG--------APMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133
Query: 415 --RKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ 472
KG PP +P P +P+ P +G T A P P+ G GL
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKG--GLATPS 1190
Query: 473 PF----------PARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYP 522
P P+ GL PS +G +P +P+ G S + P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 523 PPSPRAPA 530
P PA
Sbjct: 1249 PSPKGGPA 1256
Score = 48.1 bits (113), Expect = 2e-05
Identities = 88/325 (27%), Positives = 114/325 (35%), Gaps = 40/325 (12%)
Query: 237 PPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEF-G 295
P PP P A P + L K V L P+ + V P + G + +
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 296 SALLAALNTLGPGSFGAG---LGAQGPRSSTPEC----PVVNGSEWG----LAAPLSPER 344
S+ A T P A GA P ++TP P +W A P SP +
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP-K 974
Query: 345 GSPGRPA--FLRSPGLCGPGPVPGGLSVPTPCGRG-----AGDFSEADLADRAFPVRGAG 397
G P P+ +P P GG + P+P G + A FP +GA
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP-KGAS 1033
Query: 398 --PIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPE-KETEAPRLRGRATAV 454
P A +G A L KGAP PA+ SP P P K P AT
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAP--TTPAATLPSPKGGPATPSLKGAPTP---PAATPP 1088
Query: 455 APRPLPAAPGFSGLCVLQPF---PARSRGLGVPSQQGPTGSPGCR------DRASAPRAG 505
+P+ PA P G + P P+ GL P +G +P A+ P G
Sbjct: 1089 SPKGGPATPSPKG-APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG 1147
Query: 506 AEAGSMET-FLRNGGLYPPPSPRAP 529
A T GGL PP AP
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAP 1172
Score = 35.8 bits (81), Expect = 0.10
Identities = 81/365 (22%), Positives = 114/365 (31%), Gaps = 97/365 (26%)
Query: 209 RGGGLTSAPPGLP--PLASPPPFWELPRP------------PPPPPPPGPALLPRRLREL 254
+GG T + G P P +PP E P P P P P G LP +
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS- 1511
Query: 255 RGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGL 314
KEV P +R ++P S++ A LA L P +
Sbjct: 1512 SPKEVPATPSSR---RDPIAPTATLLSKKT-----------PATLAPKEALIPPAMTVPS 1557
Query: 315 GAQGPRSSTP-ECPVVNGSEWGLAAPL---SPERGSPGRPAFLRSPGLCGPGP----VPG 366
+ P TP E P S+ + P S +G+P L P + P P P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 367 GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPAS 426
++ P+P GP A KG P S
Sbjct: 1618 AVTPPSP---------------------EKGP------------ATPAPKGTP-----TS 1639
Query: 427 PAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGL--CVLQPFPARSRGLGVP 484
P +P +P G A + LPA G + L ++ P P + + P
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699
Query: 485 SQQGP-------TGSPGCRDR-------------ASAPRAGAEAGSMETFLRNGGLYPPP 524
+++GP T P C D A AP + S +T + P
Sbjct: 1700 TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK 1759
Query: 525 SPRAP 529
P AP
Sbjct: 1760 GPLAP 1764
Score = 31.2 bits (69), Expect = 2.5
Identities = 36/125 (28%), Positives = 45/125 (36%), Gaps = 23/125 (18%)
Query: 412 AALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL 471
AAL + P PP SPA C A + +P P P+ + L V
Sbjct: 36 AALGQPGPTLPPPCSPAPQQCPLSAANQ--------------ASPFPSPSTIASTPLEV- 80
Query: 472 QPFPARSRGLGVP---SQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 528
PFP S G +P + + PT P +P A A A M G PS A
Sbjct: 81 -PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG----TPSSSA 135
Query: 529 PAVCV 533
P V
Sbjct: 136 PLALV 140
Score = 30.0 bits (66), Expect = 5.6
Identities = 82/351 (23%), Positives = 118/351 (33%), Gaps = 76/351 (21%)
Query: 198 PALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPP------------PPGPA 245
P L P + G S+ G P A+ P P PP P P PA
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 246 LLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL 305
++P L K+ P TR +L + V + A +
Sbjct: 1407 VIP-----LSPKKAPATPVTREGAATPSKGDLTPPA-------VTPVSLKKAPATSAPKG 1454
Query: 306 GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVP 365
GP + + G + TP P + +A SP++ +P PA + +P L P +P
Sbjct: 1455 GPAT-PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK-APATPAPMGAPTL--PAVIP 1510
Query: 366 GG-LSVP-TPCGRGAGDFSEADLADR--------------------------AFPVRGAG 397
VP TP R A L + A P
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 398 PIAGRRRRRGWTFAA--ALRKGAPREQ----PPASPAASPCQAPR-------APEKETEA 444
P + A + KGAP + PPA + SP +AP +PEK
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 445 PRLRGRATA--VAPRPL---PAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 490
P +G T+ V P L P +P + P S+GL P+++GPT
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL--PAKKGPT 1679
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 55.8 bits (133), Expect = 9e-08
Identities = 102/402 (25%), Positives = 116/402 (28%), Gaps = 101/402 (25%)
Query: 115 PAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
P G A TG GP G P P G+ F P
Sbjct: 827 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP--------GFPGANGE 878
Query: 175 CGARAFYAAAG-----GASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPF 229
GAR G G + R RG GP GG PPG P
Sbjct: 879 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 938
Query: 230 WELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRV 289
P P PP PPG LP + RG E G + +T
Sbjct: 939 VGFPGPKGPPGPPGKDGLPGHPGQ-RG-ETGFQGKT------------------------ 972
Query: 290 REIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR 349
GP G +G QGP T P+ ERG PG
Sbjct: 973 ----------------GPPGPGGVVGPQGPTGET--------------GPIG-ERGHPGP 1001
Query: 350 PAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWT 409
P GL G G P P G D GP AG R G
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD----------------GP-AGLRGFPG-- 1042
Query: 410 FAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
+G P Q +P + P+ P +P RG A P LP PG G
Sbjct: 1043 -----ERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG-- 1093
Query: 470 VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
P PA +G G QGP G G + P AGS
Sbjct: 1094 --PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133
Score = 49.3 bits (116), Expect = 9e-06
Identities = 98/376 (26%), Positives = 122/376 (32%), Gaps = 72/376 (19%)
Query: 186 GASSRRRQRGR----NPALIVRGP-GPRRGGGLT--------SAPPGLPPLASPPPFWEL 232
GA + Q+G P ++V GP GP G+ + PPG P PP L
Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 491
Query: 233 PRPPPPPPPPGPAL-LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLR-RGSRRAGNHRVR 290
P P PPG L LP R K + + + + RG R
Sbjct: 492 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 551
Query: 291 EIEFGSALLAALNTLGPGSFGA-----GLGAQGPRS-STPECPVVN-------GSEWGLA 337
G GPGS GA G QGPR P P G++ G
Sbjct: 552 PGPVG----------GPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 601
Query: 338 APLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAG 397
P P G+ G F PGL G G P G D + D RG
Sbjct: 602 MPGEP--GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE--DGEIGPRGLP 657
Query: 398 PIAGRRRRRGWTFAAALRKGAPREQP--PASPAASPCQAPRAPEKETEAPRLRGRATAVA 455
AG R G PR P P P + P P+ +
Sbjct: 658 GEAGPRGLLG-----------PRGTPGAPGQPGMAGVDGPPGPKGN------------MG 694
Query: 456 PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFL 515
P+ P PG G Q P +G P ++GP G PG A P A G
Sbjct: 695 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL---AGLPGADGPPGHPGKEG 751
Query: 516 RNG--GLYPPPSPRAP 529
++G G PP P+ P
Sbjct: 752 QSGEKGALGPPGPQGP 767
Score = 44.3 bits (103), Expect = 3e-04
Identities = 85/299 (28%), Positives = 98/299 (32%), Gaps = 40/299 (13%)
Query: 206 GPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRT 265
GP GG+ P G P P E P PP PP E GL P
Sbjct: 973 GPPGPGGVVG-PQG--PTGETGPIGERGHPGPPGPPG---------------EQGL-PGA 1013
Query: 266 RGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSST 323
G P + S + G +R L PG+ GA GL G +GP+
Sbjct: 1014 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG-- 1063
Query: 324 PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSE 383
P PV + E G A P G PGRP PG G PG P GR G
Sbjct: 1064 PPGPVGSPGERGSAGTAGPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGP 1121
Query: 384 ADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKET 442
L A P G G + G + PP P P AP +
Sbjct: 1122 VGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180
Query: 443 E-APR----LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
E PR + G+ R P PG GL L P G GP G PG R
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239
Score = 40.0 bits (92), Expect = 0.005
Identities = 112/473 (23%), Positives = 149/473 (31%), Gaps = 90/473 (19%)
Query: 117 GMAAGTGRSGPGSARLGLGS--GWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
G+ G GP L L G D ++ A A A+ +A AL GP +
Sbjct: 490 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA--RIALRGPPGPMG 547
Query: 175 CGARAFYAAAGGASSRRRQRG----RNPALIVRGPGPRRGGGLTSAP--------PGLPP 222
R G+S + + G + P + PGP G P PG P
Sbjct: 548 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 607
Query: 223 LASPPPFWELPR------------PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTT 270
F LP P PP PPG +RG++ + PR
Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-------GMRGEDGEIGPRGLPGEA 660
Query: 271 CVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN 330
G R R G +A ++ GP +G QG P N
Sbjct: 661 ---------GPRGLLGPRGTPGAPGQPGMAGVD--GPPGPKGNMGPQGEPG--PPGQQGN 707
Query: 331 GSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGPVPGG------------------ 367
GL P P E+G G+P PG GP PG
Sbjct: 708 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 767
Query: 368 LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPR 420
+ P P G D S+ + + FP +G + G R G G
Sbjct: 768 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-QIGPRGEDGPEG 826
Query: 421 EQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSR 479
+ A P P + +A EK + P L G P+ PGF G + +
Sbjct: 827 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 886
Query: 480 GLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLRNGGLYP--PPSPRAP 529
G Q+GPTG G R R + G + S GG P PP R P
Sbjct: 887 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS-------GGDGPPGPPGERGP 932
Score = 35.8 bits (81), Expect = 0.10
Identities = 51/187 (27%), Positives = 61/187 (32%), Gaps = 29/187 (15%)
Query: 314 LGAQGPRSST-PECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
+G GPR PE P G P E+G G P PG GP G
Sbjct: 813 VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 872
Query: 371 PTPCGRGA-GDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAALRKGAPREQPPASP 427
P GA G+ +A + P GP G R RG T + + + PP P
Sbjct: 873 P-----GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 927
Query: 428 AASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQ 487
Q P+ P P+ P PG GL P G Q
Sbjct: 928 GERGPQGPQGP------------VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQ 969
Query: 488 GPTGSPG 494
G TG PG
Sbjct: 970 GKTGPPG 976
Score = 35.4 bits (80), Expect = 0.13
Identities = 118/458 (25%), Positives = 148/458 (32%), Gaps = 70/458 (15%)
Query: 117 GMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPH-CRLRC 175
G TG +GP R G P P AA GA + GP R
Sbjct: 982 GPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1041
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLP----PLASPPPFWE 231
G R A G + + + P V PG R G T+ P GLP P P P E
Sbjct: 1042 GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGPQGPPGPAGE 1100
Query: 232 LPRPPPPPP-----------------PPGPALLPRRLRELRGK--EVGLR---------- 262
P P P GPA P + +G+ E G +
Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-KGEIGEPGQKGSKGDKGENG 1159
Query: 263 -PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRS 321
P G V +P + G G R ++ FG PG G +G QG
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGP-RGQQGMFGQKGDEGARGF-PGPPGP-IGLQG--- 1213
Query: 322 STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDF 381
P P G E G P+ P G PG G GP PG + G G+
Sbjct: 1214 -LPGPPGEKG-ENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVG----GVGEK 1266
Query: 382 SEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASPCQ 433
E A P AG + G + RG A KG P + P P
Sbjct: 1267 GEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-PVG 1324
Query: 434 APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGS 492
P P E P G+ + PG G P P+ G G P ++GP G+
Sbjct: 1325 FPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGA 1379
Query: 493 PGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G R A EAG+ + G P P+ PA
Sbjct: 1380 AGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1413
Score = 34.7 bits (78), Expect = 0.23
Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)
Query: 343 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 394
E G PG+P G GP PG P G +GA G+ + PV
Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1408
Query: 395 GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 446
GP G R G L A ++ PP P + + E P
Sbjct: 1409 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1468
Query: 447 LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 506
L G + P G GL Q P G+P GP G PG
Sbjct: 1469 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1525
Query: 507 EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 536
GS + G GL PP SP P +Q L
Sbjct: 1526 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1558
Score = 32.0 bits (71), Expect = 1.5
Identities = 86/343 (25%), Positives = 108/343 (31%), Gaps = 73/343 (21%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264
PGP+ G PG P P LP P P PPG + +GK P
Sbjct: 687 PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-------KGPQGK-----PG 733
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTP 324
G G+ H +E + G LGP +G GPR
Sbjct: 734 LAGLP----------GADGPPGHPGKEGQSGEK-----GALGPPGPQGPIGYPGPRG--- 775
Query: 325 ECPVVNGSEW--GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 382
V G++ GL E+G G P F GL G G + P G +
Sbjct: 776 ----VKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGDRGEVGQIG---PRGEDGPEGP 827
Query: 383 EADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP------PASPAASPCQAPR 436
+ RA P GP +G+ +G L R+ P P P A+ + R
Sbjct: 828 KG----RAGPTGDPGP-SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882
Query: 437 A------PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------LGV 483
P + RG A P P G SG P P RG +G
Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG-PPGPPGERGPQGPQGPVGF 941
Query: 484 PSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 526
P +GP G PG P E G G PP P
Sbjct: 942 PGPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 977
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 55.8 bits (133), Expect = 9e-08
Identities = 102/402 (25%), Positives = 116/402 (28%), Gaps = 101/402 (25%)
Query: 115 PAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
P G A TG GP G P P G+ F P
Sbjct: 776 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP--------GFPGANGE 827
Query: 175 CGARAFYAAAG-----GASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPF 229
GAR G G + R RG GP GG PPG P
Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887
Query: 230 WELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRV 289
P P PP PPG LP + RG E G + +T
Sbjct: 888 VGFPGPKGPPGPPGKDGLPGHPGQ-RG-ETGFQGKT------------------------ 921
Query: 290 REIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR 349
GP G +G QGP T P+ ERG PG
Sbjct: 922 ----------------GPPGPGGVVGPQGPTGET--------------GPIG-ERGHPGP 950
Query: 350 PAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWT 409
P GL G G P P G D GP AG R G
Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD----------------GP-AGLRGFPG-- 991
Query: 410 FAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
+G P Q +P + P+ P +P RG A P LP PG G
Sbjct: 992 -----ERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG-- 1042
Query: 470 VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
P PA +G G QGP G G + P AGS
Sbjct: 1043 --PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082
Score = 49.3 bits (116), Expect = 9e-06
Identities = 98/376 (26%), Positives = 122/376 (32%), Gaps = 72/376 (19%)
Query: 186 GASSRRRQRGR----NPALIVRGP-GPRRGGGLT--------SAPPGLPPLASPPPFWEL 232
GA + Q+G P ++V GP GP G+ + PPG P PP L
Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
Query: 233 PRPPPPPPPPGPAL-LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLR-RGSRRAGNHRVR 290
P P PPG L LP R K + + + + RG R
Sbjct: 441 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 500
Query: 291 EIEFGSALLAALNTLGPGSFGA-----GLGAQGPRS-STPECPVVN-------GSEWGLA 337
G GPGS GA G QGPR P P G++ G
Sbjct: 501 PGPVG----------GPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 550
Query: 338 APLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAG 397
P P G+ G F PGL G G P G D + D RG
Sbjct: 551 MPGEP--GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE--DGEIGPRGLP 606
Query: 398 PIAGRRRRRGWTFAAALRKGAPREQP--PASPAASPCQAPRAPEKETEAPRLRGRATAVA 455
AG R G PR P P P + P P+ +
Sbjct: 607 GEAGPRGLLG-----------PRGTPGAPGQPGMAGVDGPPGPKGN------------MG 643
Query: 456 PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFL 515
P+ P PG G Q P +G P ++GP G PG A P A G
Sbjct: 644 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL---AGLPGADGPPGHPGKEG 700
Query: 516 RNG--GLYPPPSPRAP 529
++G G PP P+ P
Sbjct: 701 QSGEKGALGPPGPQGP 716
Score = 44.3 bits (103), Expect = 3e-04
Identities = 85/299 (28%), Positives = 98/299 (32%), Gaps = 40/299 (13%)
Query: 206 GPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRT 265
GP GG+ P G P P E P PP PP E GL P
Sbjct: 922 GPPGPGGVVG-PQG--PTGETGPIGERGHPGPPGPPG---------------EQGL-PGA 962
Query: 266 RGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSST 323
G P + S + G +R L PG+ GA GL G +GP+
Sbjct: 963 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG-- 1012
Query: 324 PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSE 383
P PV + E G A P G PGRP PG G PG P GR G
Sbjct: 1013 PPGPVGSPGERGSAGTAGPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGP 1070
Query: 384 ADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKET 442
L A P G G + G + PP P P AP +
Sbjct: 1071 VGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129
Query: 443 E-APR----LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
E PR + G+ R P PG GL L P G GP G PG R
Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188
Score = 40.0 bits (92), Expect = 0.005
Identities = 112/473 (23%), Positives = 149/473 (31%), Gaps = 90/473 (19%)
Query: 117 GMAAGTGRSGPGSARLGLGS--GWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
G+ G GP L L G D ++ A A A+ +A AL GP +
Sbjct: 439 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA--RIALRGPPGPMG 496
Query: 175 CGARAFYAAAGGASSRRRQRG----RNPALIVRGPGPRRGGGLTSAP--------PGLPP 222
R G+S + + G + P + PGP G P PG P
Sbjct: 497 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 556
Query: 223 LASPPPFWELPR------------PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTT 270
F LP P PP PPG +RG++ + PR
Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-------GMRGEDGEIGPRGLPGEA 609
Query: 271 CVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN 330
G R R G +A ++ GP +G QG P N
Sbjct: 610 ---------GPRGLLGPRGTPGAPGQPGMAGVD--GPPGPKGNMGPQGEPG--PPGQQGN 656
Query: 331 GSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGPVPGG------------------ 367
GL P P E+G G+P PG GP PG
Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 716
Query: 368 LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPR 420
+ P P G D S+ + + FP +G + G R G G
Sbjct: 717 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-QIGPRGEDGPEG 775
Query: 421 EQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSR 479
+ A P P + +A EK + P L G P+ PGF G + +
Sbjct: 776 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 835
Query: 480 GLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLRNGGLYP--PPSPRAP 529
G Q+GPTG G R R + G + S GG P PP R P
Sbjct: 836 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS-------GGDGPPGPPGERGP 881
Score = 35.8 bits (81), Expect = 0.10
Identities = 51/187 (27%), Positives = 61/187 (32%), Gaps = 29/187 (15%)
Query: 314 LGAQGPRSST-PECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
+G GPR PE P G P E+G G P PG GP G
Sbjct: 762 VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 821
Query: 371 PTPCGRGA-GDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAALRKGAPREQPPASP 427
P GA G+ +A + P GP G R RG T + + + PP P
Sbjct: 822 P-----GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 876
Query: 428 AASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQ 487
Q P+ P P+ P PG GL P G Q
Sbjct: 877 GERGPQGPQGP------------VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQ 918
Query: 488 GPTGSPG 494
G TG PG
Sbjct: 919 GKTGPPG 925
Score = 35.4 bits (80), Expect = 0.13
Identities = 118/458 (25%), Positives = 148/458 (32%), Gaps = 70/458 (15%)
Query: 117 GMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPH-CRLRC 175
G TG +GP R G P P AA GA + GP R
Sbjct: 931 GPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFP 990
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLP----PLASPPPFWE 231
G R A G + + + P V PG R G T+ P GLP P P P E
Sbjct: 991 GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGPQGPPGPAGE 1049
Query: 232 LPRPPPPPP-----------------PPGPALLPRRLRELRGK--EVGLR---------- 262
P P P GPA P + +G+ E G +
Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-KGEIGEPGQKGSKGDKGENG 1108
Query: 263 -PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRS 321
P G V +P + G G R ++ FG PG G +G QG
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGP-RGQQGMFGQKGDEGARGF-PGPPGP-IGLQG--- 1162
Query: 322 STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDF 381
P P G E G P+ P G PG G GP PG + G G+
Sbjct: 1163 -LPGPPGEKG-ENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVG----GVGEK 1215
Query: 382 SEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASPCQ 433
E A P AG + G + RG A KG P + P P
Sbjct: 1216 GEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-PVG 1273
Query: 434 APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGS 492
P P E P G+ + PG G P P+ G G P ++GP G+
Sbjct: 1274 FPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGA 1328
Query: 493 PGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G R A EAG+ + G P P+ PA
Sbjct: 1329 AGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1362
Score = 34.7 bits (78), Expect = 0.23
Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)
Query: 343 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 394
E G PG+P G GP PG P G +GA G+ + PV
Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1357
Query: 395 GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 446
GP G R G L A ++ PP P + + E P
Sbjct: 1358 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1417
Query: 447 LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 506
L G + P G GL Q P G+P GP G PG
Sbjct: 1418 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1474
Query: 507 EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 536
GS + G GL PP SP P +Q L
Sbjct: 1475 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1507
Score = 32.0 bits (71), Expect = 1.5
Identities = 86/343 (25%), Positives = 108/343 (31%), Gaps = 73/343 (21%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264
PGP+ G PG P P LP P P PPG + +GK P
Sbjct: 636 PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-------KGPQGK-----PG 682
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTP 324
G G+ H +E + G LGP +G GPR
Sbjct: 683 LAGLP----------GADGPPGHPGKEGQSGEK-----GALGPPGPQGPIGYPGPRG--- 724
Query: 325 ECPVVNGSEW--GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 382
V G++ GL E+G G P F GL G G + P G +
Sbjct: 725 ----VKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGDRGEVGQIG---PRGEDGPEGP 776
Query: 383 EADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP------PASPAASPCQAPR 436
+ RA P GP +G+ +G L R+ P P P A+ + R
Sbjct: 777 KG----RAGPTGDPGP-SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831
Query: 437 A------PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------LGV 483
P + RG A P P G SG P P RG +G
Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG-PPGPPGERGPQGPQGPVGF 890
Query: 484 PSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 526
P +GP G PG P E G G PP P
Sbjct: 891 PGPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 926
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 55.8 bits (133), Expect = 9e-08
Identities = 102/402 (25%), Positives = 116/402 (28%), Gaps = 101/402 (25%)
Query: 115 PAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
P G A TG GP G P P G+ F P
Sbjct: 815 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP--------GFPGANGE 866
Query: 175 CGARAFYAAAG-----GASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPF 229
GAR G G + R RG GP GG PPG P
Sbjct: 867 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 926
Query: 230 WELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRV 289
P P PP PPG LP + RG E G + +T
Sbjct: 927 VGFPGPKGPPGPPGKDGLPGHPGQ-RG-ETGFQGKT------------------------ 960
Query: 290 REIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR 349
GP G +G QGP T P+ ERG PG
Sbjct: 961 ----------------GPPGPGGVVGPQGPTGET--------------GPIG-ERGHPGP 989
Query: 350 PAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWT 409
P GL G G P P G D GP AG R G
Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD----------------GP-AGLRGFPG-- 1030
Query: 410 FAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLC 469
+G P Q +P + P+ P +P RG A P LP PG G
Sbjct: 1031 -----ERGLPGAQ--GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG-- 1081
Query: 470 VLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
P PA +G G QGP G G + P AGS
Sbjct: 1082 --PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121
Score = 49.3 bits (116), Expect = 9e-06
Identities = 98/376 (26%), Positives = 122/376 (32%), Gaps = 72/376 (19%)
Query: 186 GASSRRRQRGR----NPALIVRGP-GPRRGGGLT--------SAPPGLPPLASPPPFWEL 232
GA + Q+G P ++V GP GP G+ + PPG P PP L
Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
Query: 233 PRPPPPPPPPGPAL-LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLR-RGSRRAGNHRVR 290
P P PPG L LP R K + + + + RG R
Sbjct: 480 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR 539
Query: 291 EIEFGSALLAALNTLGPGSFGA-----GLGAQGPRS-STPECPVVN-------GSEWGLA 337
G GPGS GA G QGPR P P G++ G
Sbjct: 540 PGPVG----------GPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 589
Query: 338 APLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAG 397
P P G+ G F PGL G G P G D + D RG
Sbjct: 590 MPGEP--GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE--DGEIGPRGLP 645
Query: 398 PIAGRRRRRGWTFAAALRKGAPREQP--PASPAASPCQAPRAPEKETEAPRLRGRATAVA 455
AG R G PR P P P + P P+ +
Sbjct: 646 GEAGPRGLLG-----------PRGTPGAPGQPGMAGVDGPPGPKGN------------MG 682
Query: 456 PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFL 515
P+ P PG G Q P +G P ++GP G PG A P A G
Sbjct: 683 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL---AGLPGADGPPGHPGKEG 739
Query: 516 RNG--GLYPPPSPRAP 529
++G G PP P+ P
Sbjct: 740 QSGEKGALGPPGPQGP 755
Score = 44.3 bits (103), Expect = 3e-04
Identities = 85/299 (28%), Positives = 98/299 (32%), Gaps = 40/299 (13%)
Query: 206 GPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRT 265
GP GG+ P G P P E P PP PP E GL P
Sbjct: 961 GPPGPGGVVG-PQG--PTGETGPIGERGHPGPPGPPG---------------EQGL-PGA 1001
Query: 266 RGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA-GL-GAQGPRSST 323
G P + S + G +R L PG+ GA GL G +GP+
Sbjct: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL--------PGAQGAPGLKGGEGPQG-- 1051
Query: 324 PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSE 383
P PV + E G A P G PGRP PG G PG P GR G
Sbjct: 1052 PPGPVGSPGERGSAGTAGPI-GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-GVQGP 1109
Query: 384 ADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS-PCQAPRAPEKET 442
L A P G G + G + PP P P AP +
Sbjct: 1110 VGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168
Query: 443 E-APR----LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
E PR + G+ R P PG GL L P G GP G PG R
Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227
Score = 40.0 bits (92), Expect = 0.005
Identities = 112/473 (23%), Positives = 149/473 (31%), Gaps = 90/473 (19%)
Query: 117 GMAAGTGRSGPGSARLGLGS--GWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLR 174
G+ G GP L L G D ++ A A A+ +A AL GP +
Sbjct: 478 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA--RIALRGPPGPMG 535
Query: 175 CGARAFYAAAGGASSRRRQRG----RNPALIVRGPGPRRGGGLTSAP--------PGLPP 222
R G+S + + G + P + PGP G P PG P
Sbjct: 536 LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 595
Query: 223 LASPPPFWELPR------------PPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTT 270
F LP P PP PPG +RG++ + PR
Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-------GMRGEDGEIGPRGLPGEA 648
Query: 271 CVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVN 330
G R R G +A ++ GP +G QG P N
Sbjct: 649 ---------GPRGLLGPRGTPGAPGQPGMAGVD--GPPGPKGNMGPQGEPG--PPGQQGN 695
Query: 331 GSEWGLAAPLSP-----ERGSPGRPAFLRSPGLCGPGPVPGG------------------ 367
GL P P E+G G+P PG GP PG
Sbjct: 696 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 755
Query: 368 LSVPTPCGRGAGD------FSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPR 420
+ P P G D S+ + + FP +G + G R G G
Sbjct: 756 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-QIGPRGEDGPEG 814
Query: 421 EQPPASPAASPCQAPRAPEK-ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSR 479
+ A P P + +A EK + P L G P+ PGF G + +
Sbjct: 815 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874
Query: 480 GLGVPSQQGPTGSPGCRD-RASAPRAGAEAGSMETFLRNGGLYP--PPSPRAP 529
G Q+GPTG G R R + G + S GG P PP R P
Sbjct: 875 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS-------GGDGPPGPPGERGP 920
Score = 35.8 bits (81), Expect = 0.10
Identities = 51/187 (27%), Positives = 61/187 (32%), Gaps = 29/187 (15%)
Query: 314 LGAQGPRSST-PECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
+G GPR PE P G P E+G G P PG GP G
Sbjct: 801 VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 860
Query: 371 PTPCGRGA-GDFSEADLADRAFPVRGAGPIA--GRRRRRGWTFAAALRKGAPREQPPASP 427
P GA G+ +A + P GP G R RG T + + + PP P
Sbjct: 861 P-----GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 915
Query: 428 AASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQ 487
Q P+ P P+ P PG GL P G Q
Sbjct: 916 GERGPQGPQGP------------VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQ 957
Query: 488 GPTGSPG 494
G TG PG
Sbjct: 958 GKTGPPG 964
Score = 35.4 bits (80), Expect = 0.13
Identities = 118/458 (25%), Positives = 148/458 (32%), Gaps = 70/458 (15%)
Query: 117 GMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPH-CRLRC 175
G TG +GP R G P P AA GA + GP R
Sbjct: 970 GPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1029
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLP----PLASPPPFWE 231
G R A G + + + P V PG R G T+ P GLP P P P E
Sbjct: 1030 GERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGPQGPPGPAGE 1088
Query: 232 LPRPPPPPP-----------------PPGPALLPRRLRELRGK--EVGLR---------- 262
P P P GPA P + +G+ E G +
Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD-KGEIGEPGQKGSKGDKGENG 1147
Query: 263 -PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRS 321
P G V +P + G G R ++ FG PG G +G QG
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGP-RGQQGMFGQKGDEGARGF-PGPPGP-IGLQG--- 1201
Query: 322 STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDF 381
P P G E G P+ P G PG G GP PG + G G+
Sbjct: 1202 -LPGPPGEKG-ENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVG----GVGEK 1254
Query: 382 SEADLADRAFPVRGAGPIAGRRRRRGWTFAAAL--------RKGAPREQPPASPAASPCQ 433
E A P AG + G + RG A KG P + P P
Sbjct: 1255 GEPGEAGNPGPPGEAG-VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG-PVG 1312
Query: 434 APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL-GVPSQQGPTGS 492
P P E P G+ + PG G P P+ G G P ++GP G+
Sbjct: 1313 FPGDPGPPGE-PGPAGQDGVGGDKGEDGDPGQPG----PPGPSGEAGPPGPPGKRGPPGA 1367
Query: 493 PGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G R A EAG+ + G P P+ PA
Sbjct: 1368 AGAEGRQGEKGAKGEAGAEGPPGKTG----PVGPQGPA 1401
Score = 34.7 bits (78), Expect = 0.23
Identities = 56/213 (26%), Positives = 68/213 (31%), Gaps = 22/213 (10%)
Query: 343 ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGA-GDFSEADLADRAFPVR 394
E G PG+P G GP PG P G +GA G+ + PV
Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1396
Query: 395 GAGPIA-----GRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPR 446
GP G R G L A ++ PP P + + E P
Sbjct: 1397 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1456
Query: 447 LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGA 506
L G + P G GL Q P G+P GP G PG
Sbjct: 1457 LIG---LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1513
Query: 507 EAGSMETFLRNG--GL-YPPPSPRAPAVCVQHL 536
GS + G GL PP SP P +Q L
Sbjct: 1514 NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1546
Score = 32.0 bits (71), Expect = 1.5
Identities = 86/343 (25%), Positives = 108/343 (31%), Gaps = 73/343 (21%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264
PGP+ G PG P P LP P P PPG + +GK P
Sbjct: 675 PGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-------KGPQGK-----PG 721
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTP 324
G G+ H +E + G LGP +G GPR
Sbjct: 722 LAGLP----------GADGPPGHPGKEGQSGEK-----GALGPPGPQGPIGYPGPRG--- 763
Query: 325 ECPVVNGSEW--GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 382
V G++ GL E+G G P F GL G G + P G +
Sbjct: 764 ----VKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGDRGEVGQIG---PRGEDGPEGP 815
Query: 383 EADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP------PASPAASPCQAPR 436
+ RA P GP +G+ +G L R+ P P P A+ + R
Sbjct: 816 KG----RAGPTGDPGP-SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 870
Query: 437 A------PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------LGV 483
P + RG A P P G SG P P RG +G
Sbjct: 871 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG-PPGPPGERGPQGPQGPVGF 929
Query: 484 PSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSP 526
P +GP G PG P E G G PP P
Sbjct: 930 PGPKGPPGPPGKDGLPGHPGQRGETGFQ-------GKTGPPGP 965
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 55.5 bits (132), Expect = 1e-07
Identities = 112/377 (29%), Positives = 126/377 (33%), Gaps = 63/377 (16%)
Query: 186 GASSRRRQRG-------RNPALIVRGPGPR--RGGGLTSAPPGLPPLASPPPFWELPRPP 236
G R QRG R P I PGP+ GG + PPG P P P
Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963
Query: 237 PPPPPPGPALLPRRLRELRGKEVGLRPRT-RGWTTCVVSPNLRRGSRRAGNHRVREIEFG 295
PP PPG LP + RG E G + +T VV P G R G
Sbjct: 964 GPPGPPGKDGLPGHPGQ-RG-ETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPG 1021
Query: 296 -------SALLAALNTLG-PGSFGAGLGAQGPRSSTPECPVVNG--SEWGLAAP-----L 340
L T G PG G G GP P + G + GL P L
Sbjct: 1022 PPGEQGLPGLAGKEGTKGDPGPAGLP-GKDGP-------PGLRGFPGDRGLPGPVGALGL 1073
Query: 341 SPERGSPGRPAFLRSPGLCGP----GPV-----PGGLSVPTPCG-RGA----GDFSEADL 386
G PG P SPG GP GP+ PG P P G +GA G A
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133
Query: 387 ADRAFPVRGAGPIA-----GRRRRRGWTFAAALR--KGAPREQPPASPAA--SPCQAPRA 437
PV GP G +G + KG EQ P P P P
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193
Query: 438 PEKETE-APR----LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGS 492
+ E PR L G+ PR P PG GL L P G Q GP G
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253
Query: 493 PGCRDRASAPRAGAEAG 509
PG R + AP A G
Sbjct: 1254 PGPRGPSGAPGADGPQG 1270
Score = 51.6 bits (122), Expect = 2e-06
Identities = 98/374 (26%), Positives = 115/374 (30%), Gaps = 55/374 (14%)
Query: 181 YAAAGGASSRRRQRGR----NPALIVRGP-GPRRGGGLTSAPPGLPPLAS--------PP 227
Y GG + Q+G P +++ GP GP GL P + P PP
Sbjct: 442 YEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPP 501
Query: 228 PFWELPRPPPPPPPPGPAL-LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGN 286
LP P PPG L LP R G + G +G +
Sbjct: 502 GRPGLPGADGLPGPPGTMLMLPFRFGG--GGDAG-----------------SKGPMVSAQ 542
Query: 287 HRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 346
+ A LA GP G GP P + G E G P P RG
Sbjct: 543 ESQAQAILQQARLALRGPAGPMGLTGRPGPVGP----PGSGGLKG-EPGDVGPQGP-RGV 596
Query: 347 PGRPAFLRSPGLCGPGPVPGGLSVPTPCG----RG----AGDFSEADLADRAFPVRGAGP 398
G P PG G G +P G RG AG E P GP
Sbjct: 597 QGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP 656
Query: 399 IAGRRRRRGWTFAAALRKGAPREQPPAS---PAASPCQAPRAPEKETEAPRLRGRATAVA 455
G RG R G P E P P P P P T G V
Sbjct: 657 -PGDDGERGDDGEVGPR-GLPGEPGPRGLLGPKGPP--GPPGPPGVTGMDGQPGPKGNVG 712
Query: 456 PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFL 515
P+ P PG G Q P +G P ++GP G PG A G
Sbjct: 713 PQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPG 772
Query: 516 RNGGLYPPPSPRAP 529
GG PP P+ P
Sbjct: 773 EKGG-QGPPGPQGP 785
Score = 50.1 bits (118), Expect = 5e-06
Identities = 93/341 (27%), Positives = 116/341 (34%), Gaps = 50/341 (14%)
Query: 197 NPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRG 256
N I G G RG G P + P E PP P GPA LP
Sbjct: 437 NQDTIYEGIGGPRG---EKGQKGEPAIIEPGMLIE-----GPPGPEGPAGLPG------- 481
Query: 257 KEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAG--L 314
P T G T V P R R G + + L P FG G
Sbjct: 482 -----PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLML----PFRFGGGGDA 532
Query: 315 GAQGPRSSTPEC---PVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVP 371
G++GP S E ++ + L P P G GRP + PG G PG +
Sbjct: 533 GSKGPMVSAQESQAQAILQQARLALRGPAGP-MGLTGRPGPVGPPGSGGLKGEPGDVGPQ 591
Query: 372 TPCG--RGAGDFSEADLADRAFP--VRGAGPIAGRRRRRGWTFAAAL--RKGAPREQPPA 425
P G G + RA RG G + RG+ A L KG + P+
Sbjct: 592 GPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPS 651
Query: 426 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ--PFPARSRGL-G 482
P P P + E RG V PR LP PG GL + P P G+ G
Sbjct: 652 GP-------PGPPGDDGE----RGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700
Query: 483 VPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPP 523
+ Q GP G+ G + P G+ G + PP
Sbjct: 701 MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741
Score = 47.8 bits (112), Expect = 3e-05
Identities = 85/328 (25%), Positives = 101/328 (30%), Gaps = 73/328 (22%)
Query: 205 PGPRRGGGL-----TSAPPGLPPLASPPPFWELPRPPP------------PPPPPGPALL 247
PGPR GL P G P P LP PP PP PPGP
Sbjct: 1200 PGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP--- 1256
Query: 248 PRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP 307
RG P P G+ A + E G P
Sbjct: 1257 -------RG------PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE----------P 1293
Query: 308 GSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGG 367
G G G G GP+ E S G A P P +G PG SPG G PG
Sbjct: 1294 GLPGEG-GPPGPKGERGEKGESGPS--GAAGPPGP-KGPPGDDGPKGSPGPVGFPGDPGP 1349
Query: 368 LSVPTPCGRGA-----GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ 422
P P G+ GD E P GP G P ++
Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP-----------------SGPPGKR 1392
Query: 423 PPASPAASPC-QAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGL 481
P PA Q + + E G+ + P+ P PG GL + P P +GL
Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI-PGPVGEQGL 1451
Query: 482 GVPSQQGPTGSPGCRDRASAPRAGAEAG 509
P GP G PG P ++G
Sbjct: 1452 --PGSPGPDGPPGPMGPPGLPGLKGDSG 1477
Score = 39.7 bits (91), Expect = 0.007
Identities = 66/253 (26%), Positives = 83/253 (32%), Gaps = 55/253 (21%)
Query: 315 GAQGPRSST--PECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSV-- 370
G QGP+ S P P NG + G RG+PG+P G GP G +
Sbjct: 877 GRQGPKGSIGFPGFPGANGEKGG--------RGTPGKPGPRGQRGPTGPRGERGPRGITG 928
Query: 371 -PTPCGRGAGDFSEADLADRA---------FPVRGAGP-------IAGRRRRRGWTFAAA 413
P P G GD +R FP P + G +RG T
Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 988
Query: 414 LR-----------KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGR-ATAVAPRP--L 459
+G E P P P P E P L G+ T P P L
Sbjct: 989 KTGPPGPPGVVGPQGPTGETGPMGERGHP--GPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046
Query: 460 PAA---PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLR 516
P PG G + P LG+ +GP G PG A +P AG+
Sbjct: 1047 PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG---PAGSPGERGPAGAAGPI-- 1101
Query: 517 NGGLYPPPSPRAP 529
G+ P P+ P
Sbjct: 1102 --GIPGRPGPQGP 1112
Score = 38.9 bits (89), Expect = 0.012
Identities = 111/438 (25%), Positives = 137/438 (31%), Gaps = 90/438 (20%)
Query: 108 AQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGA--------ALFGR 159
A++ PAG TGR GP G +P V P+ R + GR
Sbjct: 553 ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD-VGPQGPRGVQGPPGPAGKPGRRGR 611
Query: 160 AVHTAALSGPHCRLRCGARAFYAAAG--GASSRRRQRGRNPALIVRGPGPRRGGGLTSAP 217
A A P G R F AG G R G + G RG P
Sbjct: 612 AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGP 671
Query: 218 PGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNL 277
GLP P PP PP PPG + G + P+ P
Sbjct: 672 RGLPGEPGPRGLLGPKGPPGPPGPPG----------VTGMDGQPGPKGNVGPQGEPGPPG 721
Query: 278 RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLA 337
++G+ A L +GP G +GP P P + G++
Sbjct: 722 QQGNPGA-----------QGLPGPQGAIGPP------GEKGPLGK-PGLPGMPGAD---- 759
Query: 338 APLSPERGSPGRPAFLRSPGLCG----PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPV 393
G PG P PG G PGP G + P P G D +
Sbjct: 760 -------GPPGHPGKEGPPGEKGGQGPPGP-QGPIGYPGPRGVKGAD-----------GI 800
Query: 394 RGAGPIAGRRRRRGWT-FAAALR-KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRA 451
RG G + G+ F + KG E P P E E P+ RG
Sbjct: 801 RGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRG---------EDGPEGPKGRGGP 851
Query: 452 TAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSM 511
P PL PG G + P G P +QGP GS G P A E G
Sbjct: 852 NG-DPGPL-GPPGEKGKLGVPGLP------GYPGRQGPKGSIGF---PGFPGANGEKGGR 900
Query: 512 ETFLRNG--GLYPPPSPR 527
T + G G P PR
Sbjct: 901 GTPGKPGPRGQRGPTGPR 918
Score = 38.9 bits (89), Expect = 0.012
Identities = 63/229 (27%), Positives = 80/229 (34%), Gaps = 15/229 (6%)
Query: 306 GPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVP 365
GP F G G + P P G E G + P G PG +PG GP P
Sbjct: 1216 GPRGFPGPPGPVGLQG-LPGPPGEKG-ETGDVGQMGPP-GPPGPRGPSGAPGADGPQGPP 1272
Query: 366 GGLSVPTPCGRGA--GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR--KGAPRE 421
GG+ P G G+ E L P G G + G + AA KG P +
Sbjct: 1273 GGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE-RGEKGESGPSGAAGPPGPKGPPGD 1331
Query: 422 QPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG- 480
P + P P P E P G+ + PG +G P P G
Sbjct: 1332 DGPKG-SPGPVGFPGDPGPPGE-PGPAGQDGPPGDKGDDGEPGQTG----SPGPTGEPGP 1385
Query: 481 LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
G P ++GP G G R A EAG + G + P +P P
Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434
Score = 37.0 bits (84), Expect = 0.046
Identities = 50/186 (26%), Positives = 58/186 (31%), Gaps = 38/186 (20%)
Query: 314 LGAQGPRSST-PECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
+G GPR PE P G G PL P E+G G P PG GP G
Sbjct: 831 IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS 430
P G G RG G R +RG P P
Sbjct: 891 PGANGEKGG--------------RGTPGKPGPRGQRG----------------PTGP--- 917
Query: 431 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 490
+ R P T P +G + P P G +G FP G P + G
Sbjct: 918 --RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975
Query: 491 GSPGCR 496
G PG R
Sbjct: 976 GHPGQR 981
Score = 37.0 bits (84), Expect = 0.046
Identities = 83/326 (25%), Positives = 103/326 (31%), Gaps = 63/326 (19%)
Query: 205 PGPRRGGGLTSAP-----PGLPPLASPPPFWELPRPPPPPPPPGPALLP-RRLRELRGKE 258
PGP G P PG L P L PP PPGPA P R
Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100
Query: 259 VGL--RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGA 316
+G+ RP +G P G + A + + G L GP G
Sbjct: 1101 IGIPGRPGPQG-------PPGPAGEKGAPGEKGPQGPAGRDGLQ-----GPVGLPGPAGP 1148
Query: 317 QGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPV-----PGGLSV 370
GP P +G + + P ++GS G PG GP GP+ G
Sbjct: 1149 VGP-------PGEDGDKGEIGEP--GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGE 1199
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIA-----GRRRRRGWTFAAALRKGAPREQPPA 425
P P G+ + D R FP GP+ G +G T + G P P
Sbjct: 1200 PGPRGQQGLFGQKGDEGPRGFP-GPPGPVGLQGLPGPPGEKGETGDVG-QMGPPGPPGPR 1257
Query: 426 SPAASP-CQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG---- 480
P+ +P P+ P P G P PG G P P RG
Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG----PPGPKGERGEKGE 1313
Query: 481 ------------LGVPSQQGPTGSPG 494
G P GP GSPG
Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGPKGSPG 1339
Score = 35.4 bits (80), Expect = 0.13
Identities = 60/215 (27%), Positives = 72/215 (33%), Gaps = 38/215 (17%)
Query: 343 ERGSPGRPAFLRSPGLCG-PGPV--PGGLSVPTPCGRGA--GDFSEADLADRAFPVRGAG 397
++G G P SPG G PGP PG P P G G+ A P G
Sbjct: 1364 DKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG 1423
Query: 398 PIAGRRRRRGWTFAAALR-----------KGAPREQPPASPAASP----CQAPRAPEKET 442
PI G + G LR G+P P P P + P+ E
Sbjct: 1424 PI-GPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK 1482
Query: 443 EAPRL------RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
P L G R LP G SG P +G+ PS GP G PG
Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSG-------PKGEQGITGPS--GPIGPPGPP 1533
Query: 497 DRASAP-RAGAEAGSMETFLRNGGLYP-PPSPRAP 529
P GA+ S T + +P PP P P
Sbjct: 1534 GLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP 1568
Score = 34.3 bits (77), Expect = 0.30
Identities = 73/298 (24%), Positives = 99/298 (33%), Gaps = 39/298 (13%)
Query: 92 GPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARA 151
GPK R ++ S AA P G G GP + +G DP P A
Sbjct: 1303 GPKG----ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358
Query: 152 LGA-------ALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRG 204
G G+ P G R A G R+ ++G + G
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA-GPEGRQGEKGAKGEAGLEG 1417
Query: 205 P-------GPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGK 257
P GP+ G P GL + P LP P P PPGP + P L L+G
Sbjct: 1418 PPGKTGPIGPQGAPG-KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGP-MGPPGLPGLKGD 1475
Query: 258 EVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQ 317
+ ++ P +G + G+ + + S GP +G
Sbjct: 1476 SGPKGEKGHPGLIGLIGPPGEQGEK--GDRGLPGPQGSSGPKGEQGITGP---SGPIGPP 1530
Query: 318 GPRSSTPECPVVNGSEWGLAAPLSP--ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTP 373
GP P P G++ G + P P E G PG P GP PG + P P
Sbjct: 1531 GP-PGLPGPPGPKGAK-GSSGPTGPKGEAGHPGPP---------GPPGPPGEVIQPLP 1577
Score = 31.6 bits (70), Expect = 1.9
Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 20/70 (28%)
Query: 206 GPRRGGGLTS-----APPGLPPLASPP-------------PFWEL--PRPPPPPPPPGPA 245
GP+ G+T PPG P L PP P E P PP PP PPG
Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572
Query: 246 LLPRRLRELR 255
+ P ++ R
Sbjct: 1573 IQPLPIQASR 1582
>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
Length = 684
Score = 55.5 bits (132), Expect = 1e-07
Identities = 87/334 (26%), Positives = 114/334 (34%), Gaps = 50/334 (14%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFW--ELPRPPPPPPPPG-PALLPRRLRELRGKEVGL 261
PGP G++ P G+ P P LP PP PP PPG P +LP +L+ +
Sbjct: 120 PGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSI-C 178
Query: 262 RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGS-ALLAALNTLGPGSFGAGLGAQGPR 320
P G P G + ++ + E G GP +G QGPR
Sbjct: 179 PPGPPG-------PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPR 231
Query: 321 S--------------------STPECPVVNGSEWGLAAPLSPE-----RGSPGRPAFLRS 355
P P G G PE +G GRP +
Sbjct: 232 GLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA-GDRGERGPEGFRGPKGDLGRPGPKGT 290
Query: 356 PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAAL 414
PG+ GP PG G D + + P +G + G R G +
Sbjct: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAG-SKGEKG 349
Query: 415 RKGAPREQPPASPAASPCQAPRA--PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQ 472
+G E A P+ P A P + EA RG A A+ P+ P APG G
Sbjct: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH-RGSAGALGPQGPPGAPGVRG----- 403
Query: 473 PFPARSRGLGVPSQQGPTGSPG-CRDRASAPRAG 505
F + +G P GP G G DR AG
Sbjct: 404 -FQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAG 436
Score = 54.3 bits (129), Expect = 3e-07
Identities = 92/338 (27%), Positives = 117/338 (34%), Gaps = 72/338 (21%)
Query: 195 GRNPALIVRGPGPRRGGGLTSAPPGLPPLASPP------------PFWELPRPPPPPPPP 242
G +L GP P GG PPG ++ PP LP PP PP PP
Sbjct: 101 GERGSLGPPGP-PGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPP 159
Query: 243 G-PALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFG-SALLA 300
G P +LP +L+ + P G P G + ++ + E G
Sbjct: 160 GHPGVLPEGATDLQCPSI-CPPGPPG-------PPGMPGFKGPTGYKGEQGEVGKDGEKG 211
Query: 301 ALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPE--------RGSPGRPAF 352
GP +G QGPR GL PL P RG PG P
Sbjct: 212 DPGPPGPAGLPGSVGLQGPRGLR-----------GLPGPLGPPGDRGPIGFRGPPGIPG- 259
Query: 353 LRSPGLCGP----GP-----VPGGLSVPTPCGRG--AGDFSEADLADRAFPVRGAGPIAG 401
+PG G GP G L P P G AG E + + G + G
Sbjct: 260 --APGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGK----DGQNGVPG 313
Query: 402 RRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAV---APRP 458
++G A R GAP E+ P P +A EK RGRA + P
Sbjct: 314 LDGQKG----EAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE-----RGRAGELGEAGPSG 364
Query: 459 LPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
P PG +G+ + G QGP G+PG R
Sbjct: 365 EPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVR 402
Score = 42.7 bits (99), Expect = 8e-04
Identities = 108/392 (27%), Positives = 128/392 (32%), Gaps = 86/392 (21%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGK--EVGL- 261
PGP PPG P PP P PPGP P + GK E GL
Sbjct: 31 PGP-------PGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK----PGKPGEAGLP 79
Query: 262 -RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG-PGSFG-----AGL 314
P G T P G + A R G L G PG G G+
Sbjct: 80 GLPGVDGLTGRDGPP----GPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
Query: 315 GAQGP--RSSTPECPVVNGSEWGLAAP-LSPE---------------RGSPGRPAF---- 352
G +GP S P P G P + PE G PG P F
Sbjct: 136 GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPT 195
Query: 353 --------------LRSPGLCGPGPVPGGLSVPTPCG-RG-------AGDFSEADLADRA 390
PG GP +PG + + P G RG GD + R
Sbjct: 196 GYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGD--RGPIGFRG 253
Query: 391 FP-VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASP-AASPCQAPRAPEKETE--APR 446
P + GA AG R RG + R P +P A P P P K+ + P
Sbjct: 254 PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG 313
Query: 447 LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------LGVPSQQGPTGSPGCRDRA 499
L G+ P G +GL L P A S+G G + GP+G PG A
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGL-PGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDA 372
Query: 500 SAPRAGAEAGSMETFLRNGGLYPPPSPRAPAV 531
P EAG + G L P P AP V
Sbjct: 373 GMPGERGEAGHRGS---AGALGPQGPPGAPGV 401
Score = 32.0 bits (71), Expect = 1.5
Identities = 28/92 (30%), Positives = 31/92 (33%), Gaps = 5/92 (5%)
Query: 411 AAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCV 470
A A R G P P P P Q + E P L G P+ P PG G
Sbjct: 23 AGAQRVGLPGPPGPPGPPGKPGQD--GIDGEAGPPGLPGPP---GPKGAPGKPGKPGEAG 77
Query: 471 LQPFPARSRGLGVPSQQGPTGSPGCRDRASAP 502
L P G GP G+PG R P
Sbjct: 78 LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPP 109
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 53.9 bits (128), Expect = 4e-07
Identities = 83/327 (25%), Positives = 106/327 (32%), Gaps = 35/327 (10%)
Query: 203 RGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGP----------------AL 246
R G GG P L P S EL R PP PGP AL
Sbjct: 360 RSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCAL 419
Query: 247 LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG 306
LR +EVG + C R + +V E SA +A+ G
Sbjct: 420 SQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS----G 474
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPVP 365
A G+ P NG E P+ G+PG P+ P GP G P
Sbjct: 475 GAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEP 534
Query: 366 GGLSVPTPCGRGAGDFSE--ADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQP 423
TP R AG + A+ R AGP G R++P
Sbjct: 535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594
Query: 424 PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGV 483
SP+ +P P P + A + + P P PA P +P + S G
Sbjct: 595 AESPSETPGPRPAGPAGDEPA-----ESPSETPGPRPAGPAGD-----EPAESPSETPG- 643
Query: 484 PSQQGPTGSPGCRDRASAPRAGAEAGS 510
PS GPT + +A AE S
Sbjct: 644 PSPAGPTRDEPAKAGEAAELQDAEVES 670
>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
Length = 1712
Score = 53.9 bits (128), Expect = 4e-07
Identities = 107/385 (27%), Positives = 137/385 (35%), Gaps = 75/385 (19%)
Query: 169 PHCRLRCGARA---FYAAAGGASSRRRQRGRN----PALIVRGPGPRRGGGLTSAP---- 217
PH L GAR F A G S+ P L + RRG P
Sbjct: 353 PHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFI 412
Query: 218 --PGLPPLASPPPFWELPRPPPPPP----PPGPALLPRRLRELRGKEVGLRPRTRGWTTC 271
PG+P L PP + R PP PP PPGP L+ +G+ G+
Sbjct: 413 GDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR--------AGFPGL 464
Query: 272 VVSPNLRRGSRRAGNHRVREIEFGSALLAALNTL-GPGSFGAGL----GAQGPRS----- 321
SP R G+ G + L L GP F AG+ G +G R
Sbjct: 465 PGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGF-AGINGEPGRKGDRGDPGQH 523
Query: 322 STPECPVVNGSEWGLAAP-------------LSPERGSPGRPAFLRSPGLCGPGPVPG-- 366
P P + G + AP ERG PG P PG+ G PG
Sbjct: 524 GLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGV---PGMKGDDGSPGRD 580
Query: 367 GL----SVPTPCGRG----AGDFSEADLADRAFPVRGAGP----IAGRRRRRGWTFAAAL 414
GL +P P G G GD + GP + G + +RG+ A L
Sbjct: 581 GLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGL 640
Query: 415 RKGAPREQPPASPAASPCQAPRAPEKETEAPRLRG--RATAVAPRPLPAAPGFSGLCVLQ 472
G P P PA +P Q + +T+ R G R A+ P + G GL
Sbjct: 641 -PGPPGFLGPPGPAGTPGQI----DCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGL-PGP 694
Query: 473 PFPARSRGL-GVPSQQGPTGSPGCR 496
P P ++GL G+P G G PG R
Sbjct: 695 PGPTGAKGLRGIPGFAGADGGPGPR 719
Score = 46.6 bits (109), Expect = 6e-05
Identities = 55/203 (27%), Positives = 68/203 (33%), Gaps = 30/203 (14%)
Query: 311 GAGLGAQ-GPR--SSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCGPGPVPG 366
G LGAQ GPR + P P + G P +G PG P PGL GP PG
Sbjct: 774 GEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPG 833
Query: 367 GLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPAS 426
P G E L G I GR +G P ++
Sbjct: 834 LYGPPGLHGFPGAPGQEGPL--------GLPGIPGR-------------EGLPGDRGDPG 872
Query: 427 PAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQ 486
+P P RG A + P +PGF G+ + P G P
Sbjct: 873 DTGAP-----GPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGM 927
Query: 487 QGPTGSPGCRDRASAPRAGAEAG 509
G G PG + R P + EAG
Sbjct: 928 DGFQGMPGLKGRPGFPGSKGEAG 950
Score = 44.7 bits (104), Expect = 2e-04
Identities = 87/319 (27%), Positives = 111/319 (34%), Gaps = 52/319 (16%)
Query: 193 QRGRNPALIVRGPGPRRGGGLTSAP--PGLPPLASPPPFWE------LPRPPPPPPPPGP 244
+RG ++ PGPR G+ P GLP PP F +P P PGP
Sbjct: 769 ERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGP 828
Query: 245 ALLPRRLRELRGKEVGLR--PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAAL 302
+ P L G GL P G + P + G R + G+ +
Sbjct: 829 SGQPG----LYGPP-GLHGFPGAPGQEGPLGLPGIP-GREGLPGDRGDPGDTGAPGPVGM 882
Query: 303 NTLGPGSFGAGL-GAQGPRSSTPECPVVNGSEWGLAAP-LSPERGSPGRPAFLRSPGLCG 360
L AG G QG P P G + P L +RGSPG F PGL G
Sbjct: 883 KGLSGDRGDAGFTGEQGH----PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKG 938
Query: 361 PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR 420
PG +G F F + G +AG +G +G P
Sbjct: 939 RPGFPGS--------KGEAGF---------FGIPGLKGLAGEPGFKG-------SRGDPG 974
Query: 421 EQPPASPAASPCQAPRAPEKETEAPR-LRGRATAVAPRPLPAAPGFSGLCVLQPFPARSR 479
P P P EK E P L+G A + +P PG SG+ L P +
Sbjct: 975 PPGPP-PVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIK 1033
Query: 480 G----LGVPSQQGPTGSPG 494
G +GVP G G PG
Sbjct: 1034 GVKGDIGVPGIPGLPGFPG 1052
Score = 41.6 bits (96), Expect = 0.002
Identities = 79/313 (25%), Positives = 100/313 (31%), Gaps = 57/313 (18%)
Query: 205 PGPRRGGGLTSAP----PGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVG 260
PG + G P PGL P LP PP PPGPA P ++ +
Sbjct: 609 PGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQI----DCDTD 664
Query: 261 LRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPR 320
++ G + P G + G+ L + PG GA G GPR
Sbjct: 665 VKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGI----PGFAGAD-GGPGPR 719
Query: 321 SSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGD 380
GL G GR F PG GP G + +P P G G
Sbjct: 720 --------------GLP-------GDAGREGFPGPPGFIGPRGSKGAVGLPGPDG-SPGP 757
Query: 381 FS----EADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPR 436
+ +R P G G R G L KG P ++ P R
Sbjct: 758 IGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGL-KGLPGDRGP--------PGFR 808
Query: 437 APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
+ P L+G+ P PG G L FP G P Q+GP G PG
Sbjct: 809 GSQGMPGMPGLKGQPGLPGP---SGQPGLYGPPGLHGFP------GAPGQEGPLGLPGIP 859
Query: 497 DRASAPRAGAEAG 509
R P + G
Sbjct: 860 GREGLPGDRGDPG 872
Score = 41.2 bits (95), Expect = 0.002
Identities = 52/214 (24%), Positives = 67/214 (31%), Gaps = 31/214 (14%)
Query: 344 RGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEAD-----------LADRAFP 392
RG PG P PG G PG +P P G GD + + D P
Sbjct: 362 RGDPGFPGAQGEPGSQGE---PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIP 418
Query: 393 VRGAGPIA--GRRRRRGWT----------FAAALRKGAPREQPPASPAASPCQAPRAPEK 440
GP G+R G F L+ R P P + + P+ +
Sbjct: 419 ALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKG 478
Query: 441 ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR---D 497
+ R A+ + LP PG G + P R G P Q G G PG +
Sbjct: 479 DAGECRCTEGDEAI--KGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPG 536
Query: 498 RASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAV 531
AP G T G P P P +
Sbjct: 537 NIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGM 570
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/207 (25%), Positives = 68/207 (32%), Gaps = 27/207 (13%)
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP----------ERGSPGRPAFLRSP 356
PG FG G +GP P + GS+ P +P + G GRP P
Sbjct: 1286 PGIFGLK-GYRGP-PGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLP 1343
Query: 357 GLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 416
G GP G + P G + D FP GA G G A++
Sbjct: 1344 GEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFP--GAPGTVGAPGIAGIPQKIAVQP 1401
Query: 417 GAPREQPPASPAASPCQ-APRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFP 475
G Q P +P + P+ P E G+A + A PGF G
Sbjct: 1402 GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRG-------- 1453
Query: 476 ARSRGLGVPSQQGPTGSPGCRDRASAP 502
G QGP G G R +P
Sbjct: 1454 ----DEGPIGHQGPIGQEGAPGRPGSP 1476
Score = 37.7 bits (86), Expect = 0.027
Identities = 59/222 (26%), Positives = 78/222 (35%), Gaps = 39/222 (17%)
Query: 315 GAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPG-------- 366
G G ++ P V G + AP ERG PG P PG+ P + G
Sbjct: 1229 GDPGEANTLPGPVGVPGQKGDQGAP--GERGPPGSPGLQGFPGITPPSNISGAPGDKGAP 1286
Query: 367 ---GL----SVPTPCGRGAGDFSEADLADRAFP----VRGAGPIAGRRRRRGWTFAAALR 415
GL P P G A S+ D + P +G +G + R G F
Sbjct: 1287 GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPG-VFGLPGE 1345
Query: 416 KGAPREQ----PPASPAASPCQAPRAPEKETEAPRLRGRATAVA----PRPLPAAPGFSG 467
KG EQ A + P+ P+ + P G A P+ + PG G
Sbjct: 1346 KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVG 1405
Query: 468 LCVLQPFPARSRG-LGVPSQQGPTGSPGCRDRASAP-RAGAE 507
P RG G P + GP G PG AP +AG +
Sbjct: 1406 -------PQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ 1440
Score = 37.4 bits (85), Expect = 0.035
Identities = 44/167 (26%), Positives = 58/167 (34%), Gaps = 20/167 (11%)
Query: 335 GLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------RGAGDFSEADLA 387
G P+ P+ G G P PGL G G P G RG F AD
Sbjct: 61 GQPGPVGPQ-GYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGAD-- 117
Query: 388 DRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRL 447
+ G G R R G+ + + + PP S + P+ P+ + P
Sbjct: 118 ----GIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYA 173
Query: 448 RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
+ R P PG G Q P R +G Q GP G+PG
Sbjct: 174 LPKEERDRYRGEPGEPGLVG---FQGPPGRPGHVG---QMGPVGAPG 214
Score = 35.4 bits (80), Expect = 0.13
Identities = 64/266 (24%), Positives = 83/266 (31%), Gaps = 37/266 (13%)
Query: 193 QRGRNPALIVRGP--GPRRGGGLTSAPP----GLPPLASPPPFWELPRPPPPPPPPGPAL 246
Q+G A RGP P G PP G P P + L PP PPG A
Sbjct: 1246 QKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAA 1305
Query: 247 LPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLG 306
LP + P T+GW P R G + E G + G
Sbjct: 1306 LPGSKGDTGNPGAPGTPGTKGWAGDS-GPQGRPGVFGLPGEKGPRGEQGF-----MGNTG 1359
Query: 307 PGSFGAGLGAQGPRSS--------TPECPVVNGSEWGLAA-------------PLSP--- 342
P G +GP+ T P + G +A P +P
Sbjct: 1360 PTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEM 1419
Query: 343 -ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAG 401
+G PG P F +PG GP G +VP G + + P R P
Sbjct: 1420 GPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLP 1479
Query: 402 RRRRRGWTFAAALRKGAPREQPPASP 427
R + L K + +Q P P
Sbjct: 1480 GMPGRSVSIGYLLVKHSQTDQEPMCP 1505
Score = 33.1 bits (74), Expect = 0.66
Identities = 40/158 (25%), Positives = 55/158 (34%), Gaps = 30/158 (18%)
Query: 345 GSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRG-------AGDFSEADLADRAFPVRGAG 397
G+PG P F G+ G +PG P G G E A + G
Sbjct: 1182 GAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPV 1241
Query: 398 PIAGRRRRRGWTFAAALRKGAPREQ-PPASPAASPCQAPRAPEKETEAPRLRGRATAVAP 456
+ G++ +GAP E+ PP SP P + AP +G
Sbjct: 1242 GVPGQKG----------DQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKG------- 1284
Query: 457 RPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
APG GL + P +P +G TG+PG
Sbjct: 1285 -----APGIFGLKGYRGPPGPPGSAALPGSKGDTGNPG 1317
Score = 32.0 bits (71), Expect = 1.5
Identities = 56/194 (28%), Positives = 67/194 (34%), Gaps = 26/194 (13%)
Query: 315 GAQGPRSSTPECPVVNGSEWGLAAP----LSPERGSPGRPAFLRSPGLCGPGPVPGGLSV 370
G QG TP + +G+ AP L RG PG P PG G PG
Sbjct: 1263 GLQGFPGITPPSNI-SGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGT 1321
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAAS 430
P G AGD S F + G G + G T GA ++ P P
Sbjct: 1322 PGTKG-WAGD-SGPQGRPGVFGLPGEKGPRGEQGFMGNTGPT----GAVGDRGPKGPKGD 1375
Query: 431 PCQAPRAPEKETEAPRLRGRATAVAPRP----------LPAAPGFSGLCVLQPFPARSRG 480
P P AP AP + G +A +P P APG G Q P
Sbjct: 1376 P-GFPGAPGT-VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGP---QGPPGEPGF 1430
Query: 481 LGVPSQQGPTGSPG 494
G P + GP G G
Sbjct: 1431 RGAPGKAGPQGRGG 1444
Score = 29.6 bits (65), Expect = 7.3
Identities = 57/219 (26%), Positives = 71/219 (32%), Gaps = 43/219 (19%)
Query: 307 PGS--FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPV 364
PGS F G QGP+ E + E RG PG P + G GP
Sbjct: 150 PGSEGFTGPPGPQGPKGQKGEPYALPKEE------RDRYRGEPGEPGLV---GFQGPPGR 200
Query: 365 PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK----GAPR 420
PG + P G R P GP G++ RG F + G P
Sbjct: 201 PGHVGQMGPVGAPG----------RPGPPGPPGP-KGQQGNRGLGFYGVKGEKGDVGQPG 249
Query: 421 EQPPASPAASPCQAPRAP---------EKETEA-PRLRGRATAVAPRPLPAAPGFSGLCV 470
S P AP EK +E P +RG + L G G
Sbjct: 250 PNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGIS-------LKGEEGIMGFPG 302
Query: 471 LQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 509
L+ +P S G P Q+G G G + EAG
Sbjct: 303 LRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAG 341
Score = 29.3 bits (64), Expect = 9.5
Identities = 19/62 (30%), Positives = 22/62 (35%)
Query: 448 RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAE 507
RG+ V P+ PG G LQ G P GP G G R + P A
Sbjct: 60 RGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGI 119
Query: 508 AG 509
G
Sbjct: 120 PG 121
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 53.5 bits (127), Expect = 5e-07
Identities = 126/453 (27%), Positives = 165/453 (36%), Gaps = 76/453 (16%)
Query: 139 DPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFY--AAAGGASSRRRQRGR 196
D A A RA+ AL G L P C ARA + AA G A ++GR
Sbjct: 110 DQATRTAGRAS-ALAQRHVGLKPGPQRLRQPSCVHLGAARASHRLAAGGHAVKIGGKKGR 168
Query: 197 NPALIVRGPGPRR-----GGGLTSAP------PGLPPLASPPP----FWE-LPRPPPPPP 240
A +G P + G TSAP P L AS P W+ L RPPPP P
Sbjct: 169 KEARGTQGWWPPQSLTCDGRERTSAPLRRDLPPRLAHDASYPEVKGSLWQILTRPPPPRP 228
Query: 241 PPGPALLPR---RLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSA 297
P P L R R R G + G RPR + P++ GS + + R + F +
Sbjct: 229 SPAPGLTGRGQGRARGAVGLDCGCRPRPCSFG----QPDV--GSAPSRSLRGCSLRFRNT 282
Query: 298 LLAALNTLGPGSFG------AGLGAQGP--RSST-PECPVVNGSEWGLAAPLSPERGSPG 348
+ P S G G P R+ T P+ P SEW P+R SPG
Sbjct: 283 PPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWP-----GPQR-SPG 336
Query: 349 ----------RPAFL--RSPG--LCGPGPVPGGLSVPT-PCGRGAGDFSEADLADRAFPV 393
RPA L + PG P PGG+S +G ++ A P
Sbjct: 337 TGPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPT 396
Query: 394 RGAGPIA---GRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRL--- 447
+ GP A GR + +G A +PR PA P R P+ + P
Sbjct: 397 QVRGPDALGGGRLQGKGREGKAPGEGVSPR---PAPPRLGKPPRSRPPQGLAQPPETFFF 453
Query: 448 -RGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGV-PSQQG--PTGSPGCRDRASAPR 503
R R V+ A GFSG ARS LG P+ + P+ + A R
Sbjct: 454 ERSRLVPVSAELERAGHGFSG-----DAEARSGDLGARPASRSSLPSAPAPPAQQPQAAR 508
Query: 504 AGAEAGSMETFLRNGGLYPPPSPRAPAVCVQHL 536
GA L+ P + +P Q +
Sbjct: 509 HGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQV 541
Score = 37.4 bits (85), Expect = 0.035
Identities = 63/251 (25%), Positives = 84/251 (33%), Gaps = 49/251 (19%)
Query: 11 RPPPARASPAPGSSVLWLSQ-RPSLAVS----SRMVSFWLRMVSFCCSTVSRSCSTLLRS 65
RPPP R SPAPG + + R ++ + R SF V S R CS R+
Sbjct: 222 RPPPPRPSPAPGLTGRGQGRARGAVGLDCGCRPRPCSFGQPDVGSAPSRSLRGCSLRFRN 281
Query: 66 SSAPPAATDAAHMSA----------------STGTEVQMKRVGPKSWAPAPRRQRASSAQ 109
+ P +D GT Q W P P+R + +
Sbjct: 282 TPPPIPGSDQPSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEW-PGPQRSPGTGPR 340
Query: 110 VRA--ARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALS 167
A RPA + A P S R G G P P+ L ++ +
Sbjct: 341 WTAPLPRPAPLPAKRPGDSPASKRPRPG-GVSPEARDPPKGENPLCSSEAAGETGPTQVR 399
Query: 168 GPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPP--GLPPLAS 225
GP A GG + + G+ P G PR APP G PP +
Sbjct: 400 GPD-----------ALGGGRLQGKGREGKAPG---EGVSPR------PAPPRLGKPPRSR 439
Query: 226 PPPFWELPRPP 236
PP L +PP
Sbjct: 440 PPQ--GLAQPP 448
Score = 31.2 bits (69), Expect = 2.5
Identities = 46/162 (28%), Positives = 57/162 (35%), Gaps = 36/162 (22%)
Query: 226 PPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVS---PNLRRGSR 282
P FWE RP PPPP E K G + + T CV+S P RG
Sbjct: 764 PEQFWEKYRPELPPPP-----------EAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 812
Query: 283 RAG--NHRVREIE--FGSALLAALNTL---GPGSFG----------AGLGAQGPRSSTPE 325
G +H VR + A+ T+ P S G A A+GP++ E
Sbjct: 813 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQ-EE 871
Query: 326 CPVVNGSEWGLAA--PLSPERGSP--GRPAFLRSPGLCGPGP 363
V + G GSP G P L S G P P
Sbjct: 872 DEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAP 913
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 53.1 bits (126), Expect = 6e-07
Identities = 123/466 (26%), Positives = 146/466 (31%), Gaps = 67/466 (14%)
Query: 116 AGMAAGTGRSGPGSARLGLGS-GWDPARAV-----APRAARALGAALFGRAVHTAALSGP 169
AG+ G G G R +G+ G D AR AP A A G A A +GP
Sbjct: 648 AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707
Query: 170 HCRLR-------CGARAFYAAAGGASS--------RRRQRGRNPALIVRGPGPRRGGGLT 214
G F AG A + +G N + GP G
Sbjct: 708 RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP 767
Query: 215 SAPPGLPPLAS-----PPPFWELP----RPPPPPP-----PPGPALLPRRLRELRGKEVG 260
+ PPG P S PP P R PP P PPGP P LRG
Sbjct: 768 NGPPG--PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG-PAGKEGLRGPRGD 824
Query: 261 LRPRTRGWTTCVVSPNLRRGSR----RAGNHRVREIEFGSALLAALNTLG-PGSFGAGLG 315
P R V P G + AG LL A LG PGS G G
Sbjct: 825 QGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGER-G 883
Query: 316 AQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCG 375
G + E G+A P G+ G P + SPG+ G G P G
Sbjct: 884 LPGVAGAVGE-----PGPLGIAGP----PGARGPPGAVGSPGVNGAPGEAGRDGNPGNDG 934
Query: 376 RGAGDFSEADLADRAFPVRGAGPI--AGRRRRRGWTFAAALRKGAPREQPPASPAA-SPC 432
D +R +P GP+ AG G A + G E P+ P +
Sbjct: 935 PPGRDGQPGHKGERGYP-GNIGPVGAAGAPGPHG-PVGPAGKHGNRGETGPSGPVGPAGA 992
Query: 433 QAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTG- 491
PR P +G PR LP G +GL L G P GP G
Sbjct: 993 VGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP 1052
Query: 492 -------SPGCRD-RASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
P +D R P AG G PP P P
Sbjct: 1053 RGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/282 (26%), Positives = 97/282 (34%), Gaps = 64/282 (22%)
Query: 299 LAALNTLGPGSFGAGLGAQG-PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPG 357
+ A+ GP G G P S P P N GL +G+ G P +PG
Sbjct: 267 IGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGA----KGAAGLPGVAGAPG 322
Query: 358 LCGPGPVPGGLSV------------PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRR 405
L GP +PG + P P G G+ A P GP +G +
Sbjct: 323 LPGPRGIPGPVGAAGATGARGLVGEPGPAG-SKGESGNKGEPGSAGPQGPPGP-SGEEGK 380
Query: 406 RGWTFAAALR--------KGAPREQ-------------PPASPAASPCQAPRAPEKETEA 444
RG A +G+P + PP S AS R P +
Sbjct: 381 RGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGR 440
Query: 445 PRLRGRATAVAPRPLPAAPGFSGLCVLQ-------------PF-PARSRG----LGVPSQ 486
P G + PR LP +PG G + P PA +RG +G P
Sbjct: 441 P---GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGP 497
Query: 487 QGPTGSPGCR-DRASAPRAGAEAGSMETFLRNGGLYPPPSPR 527
+GPTG PG D+ A AGA N G PP P+
Sbjct: 498 KGPTGDPGKNGDKGHAGLAGARGAPGPD--GNNGAQGPPGPQ 537
Score = 50.4 bits (119), Expect = 4e-06
Identities = 127/537 (23%), Positives = 156/537 (29%), Gaps = 119/537 (22%)
Query: 63 LRSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGT 122
++ P + + G + RVG AP P R S V PAG
Sbjct: 197 VKGEPGAPGENGTPGQTGARGLPGERGRVG----APGPAGARGSDGSVGPVGPAGPIGSA 252
Query: 123 GRSG-PGS----ARLGLGSGWDPARAVAPRAARAL----------------------GAA 155
G G PG+ +G PA PR L GAA
Sbjct: 253 GPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAA 312
Query: 156 LFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTS 215
L GP G AAG +R PA G + G
Sbjct: 313 GLPGVAGAPGLPGPR-----GIPGPVGAAGATGARGLVGEPGPA------GSKGESGNKG 361
Query: 216 APPGLPPLASPPPFWELPRPPP--------PPPPPGPALLPRRLRELRGKEVGLR--PRT 265
P P P P E + P PP PPG LRG G R P
Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPG----------LRGSP-GSRGLPGA 410
Query: 266 RGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE 325
G + P R S AG VR + +GP G GP E
Sbjct: 411 DGRAGVMGPPGSRGASGPAG---VRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGK--E 465
Query: 326 CPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEAD 385
PV G P+ P G+ G P + PG GP PG GD A
Sbjct: 466 GPVGLPGIDGRPGPIGPA-GARGEPGNIGFPGPKGPTGDPGK----------NGDKGHAG 514
Query: 386 LADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAP 445
LA RGA G +G ++ G + PP P P P E P
Sbjct: 515 LAG----ARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKP 570
Query: 446 RLRGR------ATAVAPRPLPAAPGFSGLCVLQ-----------PFPARSRG-------- 480
RG PR PG SG P P ++G
Sbjct: 571 GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV 630
Query: 481 --------LGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
G+P ++G G PG + P E G+ R+G P + AP
Sbjct: 631 GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG---RDGARGAPGAVGAP 684
Score = 49.3 bits (116), Expect = 9e-06
Identities = 95/365 (26%), Positives = 120/365 (32%), Gaps = 64/365 (17%)
Query: 203 RGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLR 262
+GP RG PPG PP P P PP PP P L + GK VGL
Sbjct: 32 KGPAGDRGPRGERGPPG-PPGRDGEDGPTGP-PGPPGPPGPPGLGGNFAAQYDGKGVGLG 89
Query: 263 PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFG-------SALLAALNTLG-PGSFGAG- 313
P G ++ P G+ A + + G + A G PG G
Sbjct: 90 PGPMG----LMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145
Query: 314 -------------LGAQGPRS--STPECPVV------NGSEWGLAAPLSP-ERGSPGRPA 351
+G QG R TP P NG + P +P +G PG P
Sbjct: 146 HPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG 205
Query: 352 FLRSPGLCGPGPVP---GGLSVPTPCGRGAGDFSEADLADRAFPVRGAGP--IAGRRRRR 406
+PG G +P G + P P G D S + A P+ AGP G +
Sbjct: 206 ENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGP-AGPIGSAGPPGFPGAPGPK 264
Query: 407 GWTFAAAL-----------RKGAPREQPPASPAASP-CQAPRAPEKETEAPRLRGRATAV 454
G A G P P P +P + P + G
Sbjct: 265 GEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLP 324
Query: 455 APRPLPAAPGFSGL-----CVLQPFPARSRG----LGVPSQQGPTGSPGCRDRASAPRAG 505
PR +P G +G V +P PA S+G G P GP G PG
Sbjct: 325 GPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPN 384
Query: 506 AEAGS 510
EAGS
Sbjct: 385 GEAGS 389
Score = 44.3 bits (103), Expect = 3e-04
Identities = 113/445 (25%), Positives = 140/445 (31%), Gaps = 69/445 (15%)
Query: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGA-- 154
AP R V AA G G GP ++ G+ +P A G
Sbjct: 320 APGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEG 379
Query: 155 --ALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGG 212
G A P R G+R A G A R + GP RG
Sbjct: 380 KRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGAS----GPAGVRGPN 435
Query: 213 LTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR-TRGWTTC 271
+ PG P L P P P GP LP + G+ + P RG
Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPG----IDGRPGPIGPAGARGEPGN 491
Query: 272 VVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNG 331
+ P + + G + + G A LA PG G GAQGP P G
Sbjct: 492 IGFPGPKGPTGDPGKNGDK----GHAGLAGARG-APGPDGNN-GAQGP-------PGPQG 538
Query: 332 SEWGLAAPLSPERGSPGRPAFLRSPGLCGPG---------PVPGGLSVPTPCG-RG-AGD 380
+ G E+G PG P F PG GP + G +P P G RG G
Sbjct: 539 VQGGKG-----EQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP 593
Query: 381 FSEADLADRAFPVRGAGPIA-----GRRRRRGWTFAAALRKGAPREQPPASPAASPCQAP 435
E+ A P+ GP G + G GA P+ P+ P +
Sbjct: 594 PGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV-------GAVGTAGPSGPSGLPGERG 646
Query: 436 RA----PEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRG-------LGVP 484
A + E P LRG APG G P PA + G G
Sbjct: 647 AAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVG----APGPAGATGDRGEAGAAGPA 702
Query: 485 SQQGPTGSPGCRDRASAPRAGAEAG 509
GP GSPG R AG
Sbjct: 703 GPAGPRGSPGERGEVGPAGPNGFAG 727
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 53.1 bits (126), Expect = 6e-07
Identities = 108/403 (26%), Positives = 126/403 (31%), Gaps = 71/403 (17%)
Query: 185 GGASSRRRQRGRNPALIVRGPGPRRG---GGLTSAPPGLPPLASP-----PPFWELPRPP 236
GG +G+ V GP R G PPGLP SP P +P P
Sbjct: 745 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 804
Query: 237 PPPPPPGPALLPRRLRE-----LRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVRE 291
PP PPG P R E GK P+ T V P +G G
Sbjct: 805 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 864
Query: 292 IE---------FGSALLAALNTLGPGSFGAGLGA-QGPRS--------STPECP------ 327
+ F L ++ G G FG L A +GPR P P
Sbjct: 865 PQGPPGPPGPSFRHDKLTFIDMEGSG-FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF 923
Query: 328 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLA 387
VN S+ A L G G P F PGL GP PG P G+ G EA
Sbjct: 924 GVNSSDVPGPAGLPGVPGREGPPGF---PGLPGPPGPPGREGPPGRTGQ-KGSLGEAGAP 979
Query: 388 DRAFPVRGAGPIAGRRRRRGWTFAAALR-----KGAPREQPPASPAA------------S 430
GP AG R G A G P P PA S
Sbjct: 980 GHKGSKGAPGP-AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 1038
Query: 431 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 490
++ P+ P L+G LP A G G + FP G+ QGP
Sbjct: 1039 TARSADGPQGPPGLPGLKGDPGVPG---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 1095
Query: 491 GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCV 533
G G R P + GL PP P P V V
Sbjct: 1096 GDRGSRGEKGDPGKDG--------VGQPGLPGPPGPPGPVVYV 1130
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/347 (27%), Positives = 122/347 (35%), Gaps = 77/347 (22%)
Query: 174 RCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELP 233
R G + AG + + PA G R GL AP P P
Sbjct: 966 RTGQKGSLGEAGAPGHKGSKGAPGPA------GARGESGLAGAPGPAGP----------P 1009
Query: 234 RPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIE 293
PP PP PPGP LP ++ G W+T R G + ++
Sbjct: 1010 GPPGPPGPPGPG-LPAGFDDMEGSGGPF------WSTA------RSADGPQGPPGLPGLK 1056
Query: 294 FGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--------ERG 345
G + L PG+ G +GA G P P + G E G+A P P E+G
Sbjct: 1057 -GDPGVPGL----PGAKGE-VGADG----VPGFPGLPGRE-GIAGPQGPKGDRGSRGEKG 1105
Query: 346 SPGRPAFLRSPGLCGPGPVPGG-----------LSVPTPCGR-GAGDF-----SEADLAD 388
PG+ + PGL GP PG LSVP P GR G F + +L
Sbjct: 1106 DPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS 1164
Query: 389 RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR 448
+ RG+ G + G F+ GA PA A R P P +
Sbjct: 1165 KG--ERGSPGPKGEKGEPGSIFSP--DGGA---LGPAQKGAKGEPGFRGPPGPYGRPGYK 1217
Query: 449 GRATAVAPRPLPAAPGFSGLCVLQPFPA-RSRGLGVPSQQGPTGSPG 494
G + P PG +GL + P S G G+ GP G PG
Sbjct: 1218 GE---IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPG 1261
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/283 (27%), Positives = 100/283 (35%), Gaps = 40/283 (14%)
Query: 233 PRPPPPPPPPGPALL-PRRLRELRGKEVGLRP--RTRGWTTCVVSPNLRR--GSRRAGNH 287
PR P PPP P L + R +EV + + G T S ++ GS R
Sbjct: 687 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 746
Query: 288 RVREIEFGSALLAALNTLG-PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 346
RV+E L G PG G R+ P P + G GL P+SP
Sbjct: 747 RVKE----GGLKGQKGEPGVPGPPG--------RAGPPGSPCLPGPP-GLPCPVSPL--G 791
Query: 347 PGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG---DFSEADLADRAFPVRGAGPIAGRR 403
P PA PG GP PG P G D D + FP G G +
Sbjct: 792 PAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP--GTPGDVGPK 849
Query: 404 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAV-APRPLPAA 462
+G +G P Q P P + + + E G A+ PR P
Sbjct: 850 GDKG--DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 907
Query: 463 PGFSGLCVLQPFPAR----------SRGL-GVPSQQGPTGSPG 494
PG G+ L P R GL GVP ++GP G PG
Sbjct: 908 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 950
Score = 40.4 bits (93), Expect = 0.004
Identities = 122/465 (26%), Positives = 154/465 (33%), Gaps = 73/465 (15%)
Query: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVA-PRAARALGAA 155
AP P R S A PAG G GP GL +G+D P + A A
Sbjct: 987 APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP--GLPAGFDDMEGSGGPFWSTARSAD 1044
Query: 156 LFGRAVHTAALSG-PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLT 214
L G P GA+ A G GR +GP RG
Sbjct: 1045 GPQGPPGLPGLKGDPGVPGLPGAKG-EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 1103
Query: 215 SAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGL-----RPRTRGWT 269
PG + P P PP PPGP + + E G + + RP G+
Sbjct: 1104 KGDPGKDGVGQPGL-------PGPPGPPGPVVY---VSEQDGSVLSVPGPEGRPGFAGFP 1153
Query: 270 -TCVVSPNL-RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA--GLGAQGPRS---- 321
NL +G R + + + E GS LGP GA G +GP
Sbjct: 1154 GPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR 1213
Query: 322 ----------STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVPGGLSV 370
P P +NG L E+G PG + G+ G PGP PG
Sbjct: 1214 PGYKGEIGFPGRPGRPGMNG--------LKGEKGEPGDASL--GFGMRGMPGP-PGPPGP 1262
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPRE-QPPASPAA 429
P P G D + A+ + P G + G + G KGA E PP P
Sbjct: 1263 PGPPGTPVYDSNV--FAESSRP--GPPGLPGNQGPPG-------PKGAKGEVGPPGPPGQ 1311
Query: 430 SPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL-QPFPARSRGL-GVPSQQ 487
P + + RG A R P GF G + P P RG G+P +
Sbjct: 1312 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 1371
Query: 488 GPT--GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G + G PG P G E R G PP P P+
Sbjct: 1372 GESIRGQPGPPGPQGPPGIGYEG-------RQGPPGPPGPPGPPS 1409
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 205 PGPRRGGGL----TSAPPGLPPLASPPPF-------WELPRPPPPPPPPGP 244
PGP+ G+ PPG P PP F +P PP PP PPGP
Sbjct: 1382 PGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1432
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 4/46 (8%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPR--PPPPPPPPGPALLP 248
PGP+ G PG P PP R PP PP PPGP P
Sbjct: 1368 PGPK--GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 1411
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 53.1 bits (126), Expect = 6e-07
Identities = 108/403 (26%), Positives = 126/403 (31%), Gaps = 71/403 (17%)
Query: 185 GGASSRRRQRGRNPALIVRGPGPRRG---GGLTSAPPGLPPLASP-----PPFWELPRPP 236
GG +G+ V GP R G PPGLP SP P +P P
Sbjct: 330 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 389
Query: 237 PPPPPPGPALLPRRLRE-----LRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVRE 291
PP PPG P R E GK P+ T V P +G G
Sbjct: 390 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 449
Query: 292 IE---------FGSALLAALNTLGPGSFGAGLGA-QGPRS--------STPECP------ 327
+ F L ++ G G FG L A +GPR P P
Sbjct: 450 PQGPPGPPGPSFRHDKLTFIDMEGSG-FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF 508
Query: 328 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLA 387
VN S+ A L G G P F PGL GP PG P G+ G EA
Sbjct: 509 GVNSSDVPGPAGLPGVPGREGPPGF---PGLPGPPGPPGREGPPGRTGQ-KGSLGEAGAP 564
Query: 388 DRAFPVRGAGPIAGRRRRRGWTFAAALR-----KGAPREQPPASPAA------------S 430
GP AG R G A G P P PA S
Sbjct: 565 GHKGSKGAPGP-AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 623
Query: 431 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 490
++ P+ P L+G LP A G G + FP G+ QGP
Sbjct: 624 TARSADGPQGPPGLPGLKGDPGVPG---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 680
Query: 491 GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCV 533
G G R P + GL PP P P V V
Sbjct: 681 GDRGSRGEKGDPGKDG--------VGQPGLPGPPGPPGPVVYV 715
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/347 (27%), Positives = 122/347 (35%), Gaps = 77/347 (22%)
Query: 174 RCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELP 233
R G + AG + + PA G R GL AP P P
Sbjct: 551 RTGQKGSLGEAGAPGHKGSKGAPGPA------GARGESGLAGAPGPAGP----------P 594
Query: 234 RPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIE 293
PP PP PPGP LP ++ G W+T R G + ++
Sbjct: 595 GPPGPPGPPGPG-LPAGFDDMEGSGGPF------WSTA------RSADGPQGPPGLPGLK 641
Query: 294 FGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--------ERG 345
G + L PG+ G +GA G P P + G E G+A P P E+G
Sbjct: 642 -GDPGVPGL----PGAKGE-VGADG----VPGFPGLPGRE-GIAGPQGPKGDRGSRGEKG 690
Query: 346 SPGRPAFLRSPGLCGPGPVPGG-----------LSVPTPCGR-GAGDF-----SEADLAD 388
PG+ + PGL GP PG LSVP P GR G F + +L
Sbjct: 691 DPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS 749
Query: 389 RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR 448
+ RG+ G + G F+ GA PA A R P P +
Sbjct: 750 KG--ERGSPGPKGEKGEPGSIFSP--DGGA---LGPAQKGAKGEPGFRGPPGPYGRPGYK 802
Query: 449 GRATAVAPRPLPAAPGFSGLCVLQPFPA-RSRGLGVPSQQGPTGSPG 494
G + P PG +GL + P S G G+ GP G PG
Sbjct: 803 GE---IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPG 846
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/283 (27%), Positives = 100/283 (35%), Gaps = 40/283 (14%)
Query: 233 PRPPPPPPPPGPALL-PRRLRELRGKEVGLRP--RTRGWTTCVVSPNLRR--GSRRAGNH 287
PR P PPP P L + R +EV + + G T S ++ GS R
Sbjct: 272 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331
Query: 288 RVREIEFGSALLAALNTLG-PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 346
RV+E L G PG G R+ P P + G GL P+SP
Sbjct: 332 RVKE----GGLKGQKGEPGVPGPPG--------RAGPPGSPCLPGPP-GLPCPVSPL--G 376
Query: 347 PGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG---DFSEADLADRAFPVRGAGPIAGRR 403
P PA PG GP PG P G D D + FP G G +
Sbjct: 377 PAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP--GTPGDVGPK 434
Query: 404 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAV-APRPLPAA 462
+G +G P Q P P + + + E G A+ PR P
Sbjct: 435 GDKG--DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492
Query: 463 PGFSGLCVLQPFPAR----------SRGL-GVPSQQGPTGSPG 494
PG G+ L P R GL GVP ++GP G PG
Sbjct: 493 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 535
Score = 40.4 bits (93), Expect = 0.004
Identities = 122/465 (26%), Positives = 154/465 (33%), Gaps = 73/465 (15%)
Query: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVA-PRAARALGAA 155
AP P R S A PAG G GP GL +G+D P + A A
Sbjct: 572 APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP--GLPAGFDDMEGSGGPFWSTARSAD 629
Query: 156 LFGRAVHTAALSG-PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLT 214
L G P GA+ A G GR +GP RG
Sbjct: 630 GPQGPPGLPGLKGDPGVPGLPGAKG-EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 688
Query: 215 SAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGL-----RPRTRGWT 269
PG + P P PP PPGP + + E G + + RP G+
Sbjct: 689 KGDPGKDGVGQPGL-------PGPPGPPGPVVY---VSEQDGSVLSVPGPEGRPGFAGFP 738
Query: 270 -TCVVSPNL-RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA--GLGAQGPRS---- 321
NL +G R + + + E GS LGP GA G +GP
Sbjct: 739 GPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR 798
Query: 322 ----------STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVPGGLSV 370
P P +NG L E+G PG + G+ G PGP PG
Sbjct: 799 PGYKGEIGFPGRPGRPGMNG--------LKGEKGEPGDASL--GFGMRGMPGP-PGPPGP 847
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPRE-QPPASPAA 429
P P G D + A+ + P G + G + G KGA E PP P
Sbjct: 848 PGPPGTPVYDSNV--FAESSRP--GPPGLPGNQGPPG-------PKGAKGEVGPPGPPGQ 896
Query: 430 SPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL-QPFPARSRGL-GVPSQQ 487
P + + RG A R P GF G + P P RG G+P +
Sbjct: 897 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 956
Query: 488 GPT--GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G + G PG P G E R G PP P P+
Sbjct: 957 GESIRGQPGPPGPQGPPGIGYEG-------RQGPPGPPGPPGPPS 994
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 205 PGPRRGGGL----TSAPPGLPPLASPPPF-------WELPRPPPPPPPPGP 244
PGP+ G+ PPG P PP F +P PP PP PPGP
Sbjct: 967 PGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1017
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 4/46 (8%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPR--PPPPPPPPGPALLP 248
PGP+ G PG P PP R PP PP PPGP P
Sbjct: 953 PGPK--GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 53.1 bits (126), Expect = 6e-07
Identities = 108/403 (26%), Positives = 126/403 (31%), Gaps = 71/403 (17%)
Query: 185 GGASSRRRQRGRNPALIVRGPGPRRG---GGLTSAPPGLPPLASP-----PPFWELPRPP 236
GG +G+ V GP R G PPGLP SP P +P P
Sbjct: 510 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQ 569
Query: 237 PPPPPPGPALLPRRLRE-----LRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVRE 291
PP PPG P R E GK P+ T V P +G G
Sbjct: 570 GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPG 629
Query: 292 IE---------FGSALLAALNTLGPGSFGAGLGA-QGPRS--------STPECP------ 327
+ F L ++ G G FG L A +GPR P P
Sbjct: 630 PQGPPGPPGPSFRHDKLTFIDMEGSG-FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF 688
Query: 328 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLA 387
VN S+ A L G G P F PGL GP PG P G+ G EA
Sbjct: 689 GVNSSDVPGPAGLPGVPGREGPPGF---PGLPGPPGPPGREGPPGRTGQ-KGSLGEAGAP 744
Query: 388 DRAFPVRGAGPIAGRRRRRGWTFAAALR-----KGAPREQPPASPAA------------S 430
GP AG R G A G P P PA S
Sbjct: 745 GHKGSKGAPGP-AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 803
Query: 431 PCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPT 490
++ P+ P L+G LP A G G + FP G+ QGP
Sbjct: 804 TARSADGPQGPPGLPGLKGDPGVPG---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 860
Query: 491 GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPAVCV 533
G G R P + GL PP P P V V
Sbjct: 861 GDRGSRGEKGDPGKDG--------VGQPGLPGPPGPPGPVVYV 895
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/347 (27%), Positives = 122/347 (35%), Gaps = 77/347 (22%)
Query: 174 RCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELP 233
R G + AG + + PA G R GL AP P P
Sbjct: 731 RTGQKGSLGEAGAPGHKGSKGAPGPA------GARGESGLAGAPGPAGP----------P 774
Query: 234 RPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIE 293
PP PP PPGP LP ++ G W+T R G + ++
Sbjct: 775 GPPGPPGPPGPG-LPAGFDDMEGSGGPF------WSTA------RSADGPQGPPGLPGLK 821
Query: 294 FGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--------ERG 345
G + L PG+ G +GA G P P + G E G+A P P E+G
Sbjct: 822 -GDPGVPGL----PGAKGE-VGADG----VPGFPGLPGRE-GIAGPQGPKGDRGSRGEKG 870
Query: 346 SPGRPAFLRSPGLCGPGPVPGG-----------LSVPTPCGR-GAGDF-----SEADLAD 388
PG+ + PGL GP PG LSVP P GR G F + +L
Sbjct: 871 DPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS 929
Query: 389 RAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLR 448
+ RG+ G + G F+ GA PA A R P P +
Sbjct: 930 KG--ERGSPGPKGEKGEPGSIFSP--DGGA---LGPAQKGAKGEPGFRGPPGPYGRPGYK 982
Query: 449 GRATAVAPRPLPAAPGFSGLCVLQPFPA-RSRGLGVPSQQGPTGSPG 494
G + P PG +GL + P S G G+ GP G PG
Sbjct: 983 GE---IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPG 1026
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/283 (27%), Positives = 100/283 (35%), Gaps = 40/283 (14%)
Query: 233 PRPPPPPPPPGPALL-PRRLRELRGKEVGLRP--RTRGWTTCVVSPNLRR--GSRRAGNH 287
PR P PPP P L + R +EV + + G T S ++ GS R
Sbjct: 452 PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 511
Query: 288 RVREIEFGSALLAALNTLG-PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 346
RV+E L G PG G R+ P P + G GL P+SP
Sbjct: 512 RVKE----GGLKGQKGEPGVPGPPG--------RAGPPGSPCLPGPP-GLPCPVSPL--G 556
Query: 347 PGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAG---DFSEADLADRAFPVRGAGPIAGRR 403
P PA PG GP PG P G D D + FP G G +
Sbjct: 557 PAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP--GTPGDVGPK 614
Query: 404 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAV-APRPLPAA 462
+G +G P Q P P + + + E G A+ PR P
Sbjct: 615 GDKG--DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 672
Query: 463 PGFSGLCVLQPFPAR----------SRGL-GVPSQQGPTGSPG 494
PG G+ L P R GL GVP ++GP G PG
Sbjct: 673 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 715
Score = 40.4 bits (93), Expect = 0.004
Identities = 122/465 (26%), Positives = 154/465 (33%), Gaps = 73/465 (15%)
Query: 97 APAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVA-PRAARALGAA 155
AP P R S A PAG G GP GL +G+D P + A A
Sbjct: 752 APGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP--GLPAGFDDMEGSGGPFWSTARSAD 809
Query: 156 LFGRAVHTAALSG-PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLT 214
L G P GA+ A G GR +GP RG
Sbjct: 810 GPQGPPGLPGLKGDPGVPGLPGAKG-EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 868
Query: 215 SAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGL-----RPRTRGWT 269
PG + P P PP PPGP + + E G + + RP G+
Sbjct: 869 KGDPGKDGVGQPGL-------PGPPGPPGPVVY---VSEQDGSVLSVPGPEGRPGFAGFP 918
Query: 270 -TCVVSPNL-RRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGA--GLGAQGPRS---- 321
NL +G R + + + E GS LGP GA G +GP
Sbjct: 919 GPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR 978
Query: 322 ----------STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVPGGLSV 370
P P +NG L E+G PG + G+ G PGP PG
Sbjct: 979 PGYKGEIGFPGRPGRPGMNG--------LKGEKGEPGDASL--GFGMRGMPGP-PGPPGP 1027
Query: 371 PTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPRE-QPPASPAA 429
P P G D + A+ + P G + G + G KGA E PP P
Sbjct: 1028 PGPPGTPVYDSNV--FAESSRP--GPPGLPGNQGPPG-------PKGAKGEVGPPGPPGQ 1076
Query: 430 SPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL-QPFPARSRGL-GVPSQQ 487
P + + RG A R P GF G + P P RG G+P +
Sbjct: 1077 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 1136
Query: 488 GPT--GSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
G + G PG P G E R G PP P P+
Sbjct: 1137 GESIRGQPGPPGPQGPPGIGYEG-------RQGPPGPPGPPGPPS 1174
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 205 PGPRRGGGL----TSAPPGLPPLASPPPF-------WELPRPPPPPPPPGP 244
PGP+ G+ PPG P PP F +P PP PP PPGP
Sbjct: 1147 PGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1197
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 4/46 (8%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPR--PPPPPPPPGPALLP 248
PGP+ G PG P PP R PP PP PPGP P
Sbjct: 1133 PGPK--GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 1176
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 52.8 bits (125), Expect = 8e-07
Identities = 53/152 (34%), Positives = 56/152 (36%), Gaps = 21/152 (13%)
Query: 379 GDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAP 438
G S + A P RGA P A R RG AAA PP +PA P AP A
Sbjct: 89 GSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA------PPPTPAPPPPPAPVAA 142
Query: 439 EKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDR 498
APR A P P PA PG P R+ L P P P
Sbjct: 143 AAPARAPRAAAAAATAPPSPGPAQPG--------PRAQRAAPLAAP-PPAPAAPP----- 188
Query: 499 ASAPRAG-AEAGSMETFLRNGGLYPPPSPRAP 529
A AP AG A R L PPP P AP
Sbjct: 189 AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP 220
Score = 46.2 bits (108), Expect = 8e-05
Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 12/127 (9%)
Query: 337 AAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGA 396
A P +P R G PA + P P P P P A + A A
Sbjct: 106 ATPPAPPRAPRGAPA---AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162
Query: 397 GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAP 456
GP R + + AP PP +PAA P AP A + P + R + P
Sbjct: 163 GPAQPGPRAQ---------RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
Query: 457 RPLPAAP 463
P P AP
Sbjct: 214 PPQPPAP 220
Score = 42.7 bits (99), Expect = 8e-04
Identities = 47/148 (31%), Positives = 54/148 (36%), Gaps = 17/148 (11%)
Query: 100 PRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGWDPARAVAP-RAARALGAALFG 158
PRR A RA R A AA P A + P A AP RA RA AA
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA---PVAAAAPARAPRAAAAAATA 158
Query: 159 RAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGG--GLTSA 216
A GP + R A A A P + GPRR + +
Sbjct: 159 PPSPGPAQPGPRAQ-RAAPLAAPPPAPAA----------PPAVAPPAGPRRAPPPAVAAR 207
Query: 217 PPGLPPLASPPPFWELPRPPPPPPPPGP 244
P LPP PP + +PPPP P P P
Sbjct: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPP 235
Score = 40.4 bits (93), Expect = 0.004
Identities = 100/399 (25%), Positives = 122/399 (30%), Gaps = 107/399 (26%)
Query: 68 APPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGP 127
APP A A +A+ P P P A++A RA R A AA T P
Sbjct: 110 APPRAPRGAPAAAAAAAPP------PTPAPPPPPAPVAAAAPARAPRAAA-AAATAPPSP 162
Query: 128 GSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGA 187
G A+ G PRA RA A A A + P G R
Sbjct: 163 GPAQPG------------PRAQRAAPLA----APPPAPAAPPAVAPPAGPR--------- 197
Query: 188 SSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPP----- 242
R PA+ R P PP PP PP + P PP P PPP
Sbjct: 198 ------RAPPPAVAAREP---------PLPP--PPQPPAPPQQQQPPPPQPQPPPEGGAV 240
Query: 243 --GPALLPRRLREL---RGKEVGLRPR-TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGS 296
G A P LRE+ G G R TRG ++ A R+ G+
Sbjct: 241 RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLE------EEAAARGRLERTRLGA 294
Query: 297 ALLAALNTLGPGSFGAGLGAQGPRS--------------------STPECPVVNGSEWGL 336
LA PG A+ RS E V GSE
Sbjct: 295 --LALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSE--- 349
Query: 337 AAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGA 396
PE P + G GP + TPCG G G
Sbjct: 350 ----VPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQ------------DEGR 393
Query: 397 GPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAP 435
GP G R+ ++ AA ++G + SP P
Sbjct: 394 GPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLP 432
Score = 37.4 bits (85), Expect = 0.035
Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 15/116 (12%)
Query: 140 PARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPA 199
PA APR A A AA ARA AAA A++ P
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP- 167
Query: 200 LIVRGPGPRRGGGLTS------APPGLPPLA----SPPPFWELPRPPPPPPPPGPA 245
GP +R L + APP + P A +PPP PP PPPP PA
Sbjct: 168 ----GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219
Score = 35.0 bits (79), Expect = 0.17
Identities = 65/253 (25%), Positives = 81/253 (32%), Gaps = 49/253 (19%)
Query: 207 PRRGGGLTSAPPGLPPLASPPPFWELPRPPP-PPPPPGPALLPRRLRELRGKEVGLRPRT 265
P R G APP P A P P P PPPPP P R R
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA----- 155
Query: 266 RGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE 325
T SP + RA +A LAA P + A GPR + P
Sbjct: 156 ---ATAPPSPGPAQPGPRAQR---------AAPLAA-PPPAPAAPPAVAPPAGPRRAPP- 201
Query: 326 CPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEAD 385
P V E P P P P + P P P P G +V R G
Sbjct: 202 -PAVAARE-----PPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV-----RAGGAARPVS 250
Query: 386 LADRAFPVRGAGPIAGR------------------RRRRGWTFAAALRKGAPREQPPASP 427
L + + G+G GR R R A AL +G + P +
Sbjct: 251 LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAA 310
Query: 428 AASPCQAPRAPEK 440
+A P ++ R E+
Sbjct: 311 SARPSRSKRGGEE 323
>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
Length = 564
Score = 52.4 bits (124), Expect = 1e-06
Identities = 115/430 (26%), Positives = 144/430 (33%), Gaps = 71/430 (16%)
Query: 92 GPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGW------DPARAVA 145
GP+ A P R+S A R P + R G GLGS W P RA+
Sbjct: 162 GPR--AGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALW 219
Query: 146 PRAARALGAALFGRAVHTAALSG---PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIV 202
R A GA R A G P + G A G +RQR P+
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVG--TRARGHGGVQRQRFSAPSSHS 277
Query: 203 RGPGPRRGGGLTSAPPGLPP----LASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKE 258
G R G +S P L P AS P + P P+L + R GK
Sbjct: 278 TS-GGRPTGERSSREPLLDPSKAARASALPTARVAHASP------PSLAAAQWRLGGGKR 330
Query: 259 VGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG 318
P + +G+ R E + S L P G+ L A+
Sbjct: 331 ---------------KPTVLKGAVRTDLSTAEEEDPRSG-----RALEPAQ-GSELWARA 369
Query: 319 PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS--PGLCGPGPVPGGLSVPTPCGR 376
R +G G +P R PG+PA S P G GL+ GR
Sbjct: 370 ER---------HGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
Query: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPR 436
G+G G +A RR R LR G P +P +SPA P PR
Sbjct: 421 GSGVTHSV----------GTHALATRRGSRAPRPVGVLR-GVPHFRPLSSPA--PQSPPR 467
Query: 437 APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
+P PRL G P+ P A G+ VL P PA G G P
Sbjct: 468 SPSVRAFGPRL-GAGRLSCPQ-APRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAG 525
Query: 497 DRASAPRAGA 506
RA + GA
Sbjct: 526 RRAERGKRGA 535
>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
Length = 564
Score = 52.4 bits (124), Expect = 1e-06
Identities = 115/430 (26%), Positives = 144/430 (33%), Gaps = 71/430 (16%)
Query: 92 GPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGW------DPARAVA 145
GP+ A P R+S A R P + R G GLGS W P RA+
Sbjct: 162 GPR--AGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALW 219
Query: 146 PRAARALGAALFGRAVHTAALSG---PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIV 202
R A GA R A G P + G A G +RQR P+
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVG--TRARGHGGVQRQRFSAPSSHS 277
Query: 203 RGPGPRRGGGLTSAPPGLPP----LASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKE 258
G R G +S P L P AS P + P P+L + R GK
Sbjct: 278 TS-GGRPTGERSSREPLLDPSKAARASALPTARVAHASP------PSLAAAQWRLGGGKR 330
Query: 259 VGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG 318
P + +G+ R E + S L P G+ L A+
Sbjct: 331 ---------------KPTVLKGAVRTDLSTAEEEDPRSG-----RALEPAQ-GSELWARA 369
Query: 319 PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS--PGLCGPGPVPGGLSVPTPCGR 376
R +G G +P R PG+PA S P G GL+ GR
Sbjct: 370 ER---------HGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
Query: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPR 436
G+G G +A RR R LR G P +P +SPA P PR
Sbjct: 421 GSGVTHSV----------GTHALATRRGSRAPRPVGVLR-GVPHFRPLSSPA--PQSPPR 467
Query: 437 APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496
+P PRL G P+ P A G+ VL P PA G G P
Sbjct: 468 SPSVRAFGPRL-GAGRLSCPQ-APRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAG 525
Query: 497 DRASAPRAGA 506
RA + GA
Sbjct: 526 RRAERGKRGA 535
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 52.4 bits (124), Expect = 1e-06
Identities = 94/351 (26%), Positives = 124/351 (35%), Gaps = 43/351 (12%)
Query: 186 GASSRRRQRGRNPALIVRGPGPRRGGGLTSAP--PGLPPLASP--PPFWELPRPPPPPPP 241
G R Q+G + PGP G AP PG P A P PP E+ P PP PP
Sbjct: 400 GFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP 459
Query: 242 PGPALLPRRLRELRGKEVGLRPRTRGWTTCVVS-----------PNLRR--GSRRAGNHR 288
P + L+G++ + C+ + P L GS +
Sbjct: 460 GSPGD-----KGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514
Query: 289 VREIEFGSALLAALNTLGPGSFGAG--LGAQGPRSSTPECPVVNGSEWGLAAPLSPER-G 345
+ + G+ L + PG+ GA G++G P + G + L +P +P G
Sbjct: 515 GEKGQAGATGPKGLPGI-PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573
Query: 346 SPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVR--GAGPIAGRR 403
PG P PGL GP PGG++ G G+ L P+ G GP G
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGITFKGERGP-PGNPGLPGLPGNIGPMGPPGFGP-PGPV 631
Query: 404 RRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAP 463
+G A G P + P P Q P K P L G LP P
Sbjct: 632 GEKGIQGVA----GNPGQPGIPGPKGDPGQTITQPGK----PGLPGNPGRDGDVGLPGDP 683
Query: 464 GFSGLCVLQPFPARSR-----GLGVPSQQGPTGSPGCRDRASAPRAGAEAG 509
G G L P G+G+P GP G PG AP G
Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734
Score = 45.8 bits (107), Expect = 1e-04
Identities = 61/243 (25%), Positives = 78/243 (32%), Gaps = 22/243 (9%)
Query: 306 GPGSFGAGLGAQGP--RSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG--- 360
GP G G GP P + G P P G+PG P PGL G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL---PGLSGQKG 1205
Query: 361 ----PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRK 416
PG +PG +P P G G + P GP + R
Sbjct: 1206 DGGLPG-IPGNPGLPGPKGE-PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263
Query: 417 GAPR-EQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFP 475
G P E PP P + + + P L G P L PG GL ++ P
Sbjct: 1264 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1323
Query: 476 ARSRGLGVPSQQGPTGSPGCRDRASAP-------RAGAEAGSMETFLRNGGLYPPPSPRA 528
G P +GP+G PG P G S ++ + G PP P
Sbjct: 1324 GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1383
Query: 529 PAV 531
P +
Sbjct: 1384 PGL 1386
Score = 45.4 bits (106), Expect = 1e-04
Identities = 83/329 (25%), Positives = 108/329 (32%), Gaps = 76/329 (23%)
Query: 205 PGPRRGGGLTS-----APPGLPPLASPP--PFWELPRPPPPPPPPG--PALLPRRLRELR 255
PGP G PPG P P P + LP PP PP PG AL P+ R
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780
Query: 256 GK-----EVGLR--PRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPG 308
G GL P +G V PN + G +GP
Sbjct: 781 GPPGPPGRTGLDGLPGPKG----DVGPNGQPGP-----------------------MGPP 813
Query: 309 SFGAGLGAQGPRSSTP-----ECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG-PG 362
G+G QGP P ++G P P PG P SPG+ G PG
Sbjct: 814 GL-PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872
Query: 363 PV--PGGLSVPTPCGRGAGDFSEADLADRAFP-------VRGAGPIAGRRRRRGWTFAAA 413
P+ PG +P G ++ ++ P + G + G + G
Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932
Query: 414 L--------RKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGF 465
L KG P P P + + E P + G + + LP PG
Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992
Query: 466 SGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
GL S G+P GP G+PG
Sbjct: 993 PGL---------SGQPGLPGPPGPKGNPG 1012
Score = 44.3 bits (103), Expect = 3e-04
Identities = 69/234 (29%), Positives = 75/234 (32%), Gaps = 36/234 (15%)
Query: 307 PGSFGAGL-GAQGPRS-----STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG 360
PG G GL G GP+ P P G GL P P PG P PG
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG-RIGLEGPPGP----PGFPGPKGEPGFAL 755
Query: 361 PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR 420
PGP P P G + DR FP P GR G P
Sbjct: 756 PGP-------PGPPGLPGFKGALGPKGDRGFPGPPGPP--GRTGLDG--LPGPKGDVGPN 804
Query: 421 EQP-PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSR 479
QP P P P + P P G+ PG GL V P P R
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV--PGPPGER 862
Query: 480 GL----GVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
G G P GP GSPG +A A G M G+ PP P P
Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM-------GMMGPPGPPGP 909
Score = 43.5 bits (101), Expect = 5e-04
Identities = 88/347 (25%), Positives = 115/347 (33%), Gaps = 50/347 (14%)
Query: 198 PALIVRGPGPRRGG-GLTSAP--------PGLPPLASPPPFWELPRPPP---PPPPPGPA 245
P L V GP RG G+ AP PGLP A F PP PPGP
Sbjct: 851 PGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910
Query: 246 LLPRR--LRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALN 303
+P R + L+G + GL+ + + P +GS+ LL +
Sbjct: 911 GIPGRSGVPGLKGDD-GLQGQPG-----LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKG 964
Query: 304 TLGPGSFGAGLGAQGPRS-----STPECPVVNGSEWGLAAPLSPER--GSPGRPAFLRSP 356
G G GP+ P P ++G GL P P+ G PG+P + P
Sbjct: 965 EKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP-GLPGPPGPKGNPGLPGQPGLIGPP 1023
Query: 357 GLCG-------PGPV-----PGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRR 404
GL G PGP PG VP G + D D G + G +
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083
Query: 405 RRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEA--PRLRGRATAVAPRPLPAA 462
G G P + P P P + + P G P+ +
Sbjct: 1084 EPGLPGYP----GNPGIKGSVGDPGLP-GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138
Query: 463 PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAG 509
PG GL P G G P Q GP G G + P + G
Sbjct: 1139 PGNPGL---PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182
Score = 43.1 bits (100), Expect = 6e-04
Identities = 82/303 (27%), Positives = 108/303 (35%), Gaps = 43/303 (14%)
Query: 205 PGPR--RGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPG--PALLPRRLRELRGKEVG 260
PGPR +G PPG + PP P P P PG A P+ + G +
Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTK-- 128
Query: 261 LRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPR 320
RG+ P L+ G ++ E GS ++++L PG G G GP
Sbjct: 129 ---GERGFPGSPGFPGLQGPPGPPGIPGMKG-EPGSIIMSSL----PGPKG-NPGYPGP- 178
Query: 321 SSTPECPVVNG--SEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVPG-GLSVPTPCGR 376
P + G G+ P+ P PG P + PG G PGP GL+ P
Sbjct: 179 ------PGIQGLPGPTGIPGPIGP----PGPPGLMGPPGPPGLPGPKGNMGLNFQGP--- 225
Query: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ-PPASPAASPCQAP 435
G+ E L P G I+ ++R F +G P ++ PP P P
Sbjct: 226 -KGEKGEQGLQG---PPGPPGQISEQKRPIDVEFQKG-DQGLPGDRGPPGPPGIRGPPGP 280
Query: 436 RAPEK----ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTG 491
EK E P RG+ P PG G P R G GP G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340
Query: 492 SPG 494
PG
Sbjct: 341 PPG 343
Score = 43.1 bits (100), Expect = 6e-04
Identities = 63/249 (25%), Positives = 80/249 (32%), Gaps = 43/249 (17%)
Query: 300 AALNTLGPGSFGAGLGAQG----PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS 355
A + GP F G +G P S P P ++G AP P P P S
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP---GAPGLPGPPGPAGPHIPPS 447
Query: 356 PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALR 415
+C PGP PG P G + D D F G G I+G
Sbjct: 448 DEICEPGP-PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-ISG-------------- 491
Query: 416 KGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPL------PAAPGFSG-- 467
P QP P + P ++ E +G+A A P+ L P APGF G
Sbjct: 492 ---PPGQPGLPGLPGPPGSLGFPGQKGE----KGQAGATGPKGLPGIPGAPGAPGFPGSK 544
Query: 468 -----LCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYP 522
+ LG P G G PG + P G G P
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP 604
Query: 523 PPSPRAPAV 531
P +P P +
Sbjct: 605 PGNPGLPGL 613
Score = 43.1 bits (100), Expect = 6e-04
Identities = 65/234 (27%), Positives = 82/234 (35%), Gaps = 44/234 (18%)
Query: 307 PGSFGAGL-------GAQGPRSSTPECPVVNGSEWGLAAP----LSPERGSPGRPAFLRS 355
PGS G L G QGP P P + G E P + E+G+PG+P
Sbjct: 1240 PGSPGPALEGPKGNPGPQGP----PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1295
Query: 356 PGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFP-VRGAGPIAGRRRRRGWTFAAAL 414
PGL G PG P G FP ++G + G +A
Sbjct: 1296 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG----------SAG 1345
Query: 415 RKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPF 474
+G P P P P P ++ ++G A P +P PG GL P
Sbjct: 1346 PEGEPGLIGPPGP-------PGLPGPSGQSIIIKGDA---GPPGIPGQPGLKGL----PG 1391
Query: 475 PARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNG--GLYPPPSP 526
P +GL P GP G PG AG G + G GL PP P
Sbjct: 1392 PQGPQGL--PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGP 1443
Score = 42.4 bits (98), Expect = 0.001
Identities = 91/342 (26%), Positives = 112/342 (32%), Gaps = 50/342 (14%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPP---PFWELPRPPPPPPPPGPALLPRRLRELRGKEVGL 261
PGP+ G T PG P L P LP P P PG +P E +GL
Sbjct: 649 PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL 708
Query: 262 --RPRTRGWTTCVVSPNLRRGSRRAG--------NHRVREIEFGSALLAALNTLGPGSFG 311
P +G+ P R G + E G AL G F
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768
Query: 312 AGLGAQGPRS--STPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPG--PVPGG 367
LG +G R P P G + GL P + G G+P + PGL G G PG
Sbjct: 769 GALGPKGDRGFPGPPGPPGRTGLD-GLPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGP 826
Query: 368 LSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASP 427
+P P G+ + D P + G RG G P P P
Sbjct: 827 PGIPGPIGQPGLHGIPGEKGDPGPP---GLDVPGPPGERG-------SPGIPGAPGPIGP 876
Query: 428 AASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQ 487
SP +A + P +G + P P PG G+ P RS G+
Sbjct: 877 PGSPGLPGKA--GASGFPGTKGEMGMMGP---PGPPGPLGI------PGRSGVPGLKGDD 925
Query: 488 GPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRAP 529
G G PG P E GS GL PP P P
Sbjct: 926 GLQGQPG------LPGPTGEKGSK----GEPGLPGPPGPMDP 957
Score = 40.0 bits (92), Expect = 0.005
Identities = 50/197 (25%), Positives = 65/197 (32%), Gaps = 36/197 (18%)
Query: 335 GLAAPLSPE--RGSPGRPAFLRSPGLCG-------PGP-----VPGGLSVPTPCGR---- 376
G P P+ G PG P PG G PGP PG +P P G+
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184
Query: 377 ---GAGDFSEADL-------ADRAFP-VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPA 425
G G+ L D P + G + G + G+ G P Q P
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF-------HGFPGVQGPP 1237
Query: 426 SPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPS 485
P SP A P+ GR P P PG G+ + P + G+P
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297
Query: 486 QQGPTGSPGCRDRASAP 502
+G G PG + P
Sbjct: 1298 LKGDQGPPGLQGNPGRP 1314
Score = 36.6 bits (83), Expect = 0.060
Identities = 61/263 (23%), Positives = 84/263 (31%), Gaps = 48/263 (18%)
Query: 288 RVREIEFGSAL-LAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS 346
++R + + L L AL+ G + A P S +C + G + P G
Sbjct: 2 KLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKC-DCSGIKGEKGERGFP--GLEGH 58
Query: 347 PGRPAFLRSPGLCGPGPVPGGLSVPTPCG-------------RGAGDFSEADLADRAFPV 393
PG P F G GP G +P P G G D A
Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118
Query: 394 RGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATA 453
+G G + RG+ P SP Q P P P ++G +
Sbjct: 119 QGIPGCNGTKGERGF---------------PGSPGFPGLQGPPGP---PGIPGMKGEPGS 160
Query: 454 VAPRPLPAA---PGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGS 510
+ LP PG+ G +Q P + G+P GP G PG P G+
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPT---GIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217
Query: 511 METFLR-------NGGLYPPPSP 526
M + GL PP P
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGP 240
Score = 33.9 bits (76), Expect = 0.39
Identities = 87/337 (25%), Positives = 111/337 (32%), Gaps = 80/337 (23%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPR 264
PGP G+ PPGLP P LP P PGP +P +G+
Sbjct: 83 PGPPGPKGIRG-PPGLPGFPGTPG---LPGMPGHDGAPGPQGIPG-CNGTKGE------- 130
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTP 324
RG+ P L+ G ++ E GS ++++L PG G G GP
Sbjct: 131 -RGFPGSPGFPGLQGPPGPPGIPGMKG-EPGSIIMSSL----PGPKG-NPGYPGP----- 178
Query: 325 ECPVVNG--SEWGLAAPLSPERGSPGRPAFLRSPGLCG-PGPVPG-GLSVPTPCGRGA-- 378
P + G G+ P+ P PG P + PG G PGP GL+ P G
Sbjct: 179 --PGIQGLPGPTGIPGPIGP----PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ 232
Query: 379 ---------GDFSEA--------DLADRAFP----------VRGA-GPIAGRRRRRGWTF 410
G SE D+ P +RG GP G + +G
Sbjct: 233 GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292
Query: 411 AAALR----KGAPREQP--------PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRP 458
R K QP P P + + +T P G V PRP
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP---GPPGLVIPRP 349
Query: 459 LPAAP-GFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
G G L P G P QGP G PG
Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386
Score = 32.7 bits (73), Expect = 0.86
Identities = 53/229 (23%), Positives = 72/229 (31%), Gaps = 24/229 (10%)
Query: 324 PECPVVNGSEWGLAAPLSP-ERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFS 382
P + G + + P P E+G G P PGL GP P + P P G
Sbjct: 349 PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP-PGAAVMGPPGPPGFPGERGQ 407
Query: 383 EADLADRAFPVRGAGPIAGRRRRRGWTFAAA------------LRKGAPREQPPASPAAS 430
+ D + G + G+ G G P PP SP
Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP--GPPGSPGDK 465
Query: 431 PCQAPRAPEKETEAPRLRGRATAVA-PRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGP 489
Q + + + T ++ P P PG G FP + G GP
Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525
Query: 490 TGSPGCRDRASA---PRAGAEAGSMETFL----RNGGLYPPPSPRAPAV 531
G PG A P + E G + TF G L P +P P +
Sbjct: 526 KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574
Score = 31.2 bits (69), Expect = 2.5
Identities = 85/337 (25%), Positives = 113/337 (33%), Gaps = 70/337 (20%)
Query: 181 YAAAGGASSRRRQRGRN-----PALIVRGPGPRRGGGLTSAP------PGLPPLASPPPF 229
Y G + Q+G P L++ PR G G+T PGLP F
Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVI----PRPGTGITIGEKGNIGLPGLPGEKGERGF 375
Query: 230 WELPRPPPPPPPPGPALL----PRRLRELRGKE-----VGLR-PRTRGWTTCVVSPNLRR 279
+ PP P PPG A++ P RG++ G+ P G +P L
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435
Query: 280 GSRRAGNHRVREIEFGSALLAALNTLGPGSFG-AGL-GAQGPRSSTPECPVVNGSEWGLA 337
AG H I + PGS G GL G QG + + N G++
Sbjct: 436 PPGPAGPH----IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD-TCFNCIGTGIS 490
Query: 338 APLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAG 397
P PG+P PGL GP PG L P G E A P +G
Sbjct: 491 GP-------PGQPGL---PGLPGP---PGSLGFP-------GQKGEKGQAGATGP-KGLP 529
Query: 398 PIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPR 457
I G G+ + +P + + AP L G
Sbjct: 530 GIPGAPGAPGFP--------GSKGEPGDILTFPGMKGDKGELGSPGAPGLPG-------- 573
Query: 458 PLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPG 494
LP PG GL L G+ ++GP G+PG
Sbjct: 574 -LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 52.4 bits (124), Expect = 1e-06
Identities = 92/327 (28%), Positives = 108/327 (33%), Gaps = 69/327 (21%)
Query: 202 VRGPGPRRG--GGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEV 259
VRGP +G G S P PP F PP P PGP P L G +
Sbjct: 652 VRGPDGLKGQKGDTISCNVTYPGRHGPPGF---DGPPGPKGFPGPQGAPG----LSGSDG 704
Query: 260 GL-RPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQ- 317
RP T G P R +G FG G+
Sbjct: 705 HKGRPGTPGTAEIPGPPGFR------------------------GDMGDPGFGGEKGSSP 740
Query: 318 -GPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP----------GP--V 364
GP P P VNG + P G PG+ PG+ GP GP +
Sbjct: 741 VGP-PGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGI 799
Query: 365 PGGLSVPTPCGR-GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFA--AALRKGAPRE 421
PG L + P GR G F RGA I G+ G+ + A KG P +
Sbjct: 800 PGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGD 859
Query: 422 QPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL--QPFPARSR 479
P PA P L GR A P LP PG G L P P R
Sbjct: 860 VGPPGPAGMK-----------GLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPR 908
Query: 480 GL----GVPSQQGPTGSPGCRDRASAP 502
GL G P ++G G+ GC P
Sbjct: 909 GLPGFPGFPGERGKPGAEGCPGAKGEP 935
Score = 50.8 bits (120), Expect = 3e-06
Identities = 101/368 (27%), Positives = 125/368 (33%), Gaps = 57/368 (15%)
Query: 181 YAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAP--------PGLPPLASPPPFWEL 232
++ GA + +G +PA PGP+ G P GLP + P
Sbjct: 1061 FSGIDGARGPKGNKG-DPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGR 1119
Query: 233 PRPPP---PPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRV 289
P PP PP PG +P LR G+ PR + P +G
Sbjct: 1120 PGPPGSSGPPGCPGDHGMPG-LRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPS------- 1171
Query: 290 REIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGR 349
GS L L+ L G G GA G P PV G+ L ERG PG
Sbjct: 1172 -----GSPGLNGLHGL-KGQKGTK-GASGLHDVGPPGPV------GIPG-LKGERGDPGS 1217
Query: 350 PAFLRSPGLCG----PGPVPGGLSVPTPCG---RGAGDFSEADLADRAFPVRGAGPIAGR 402
P + PG G PGP PG P P G R D + P GP G
Sbjct: 1218 PG-ISPPGPRGKKGPPGP-PGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGP-RGA 1274
Query: 403 RRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAA 462
G + L +G P + P P P P P G+ P P
Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPP--GPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332
Query: 463 PGFSGLCVLQPFPARSRGL-GVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLY 521
G G P P +GL G P ++GPTG PG R P ++ R GL
Sbjct: 1333 QGPHGF----PGPPGEKGLPGPPGRKGPTGLPGPRGEPGPP------ADVDDCPRIPGLP 1382
Query: 522 PPPSPRAP 529
P R P
Sbjct: 1383 GAPGMRGP 1390
Score = 45.4 bits (106), Expect = 1e-04
Identities = 87/339 (25%), Positives = 110/339 (32%), Gaps = 60/339 (17%)
Query: 210 GGGLTSAPPGLPPLASP--PPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRG 267
GG P G P A P PP P PP PG P +RG + GL+ +
Sbjct: 610 GGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPG----VRGPD-GLKGQKGD 664
Query: 268 WTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRS--STPE 325
+C V+ G H GP F G GP+
Sbjct: 665 TISCNVT--------YPGRH------------------GPPGFD---GPPGPKGFPGPQG 695
Query: 326 CPVVNGSEWGLAAPLSPERGS-PGRPAFLRSPGLCGPGPVPGGLSV--PTPCGRGAGDFS 382
P ++GS+ P +P PG P F G G G G V P P G +
Sbjct: 696 APGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQ 755
Query: 383 EADLADRAFP------VRGAGPIAGRRRRRGWTFAAALRKGAPREQPPAS-PAASPCQAP 435
+ D AF RG + G + RG G P + PA P + P
Sbjct: 756 KGIPGDPAFGHLGPPGKRGLSGVPGIKGPRG-------DPGCPGAEGPAGIPGFLGLKGP 808
Query: 436 RAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGC 495
+ E P + G R P PG GL P G G P GP G G
Sbjct: 809 KGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 868
Query: 496 RDRASAP-RAGAEA----GSMETFLRNGGLYPPPSPRAP 529
+ P R GA + + GL PP P+ P
Sbjct: 869 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGP 907
Score = 45.1 bits (105), Expect = 2e-04
Identities = 93/371 (25%), Positives = 117/371 (31%), Gaps = 64/371 (17%)
Query: 181 YAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTS--------APPGLPPLASPPPFWE- 231
Y + GA + Q G V PGP GL PPGLP + P PF +
Sbjct: 844 YPGSPGAPGGKGQPGD-----VGPPGPAGMKGLPGLPGRPGAHGPPGLPGI--PGPFGDD 896
Query: 232 -LPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVR 290
LP PP P P G P E RGK P G P + S G+ +R
Sbjct: 897 GLPGPPGPKGPRGLPGFPGFPGE-RGK-----PGAEGCPGAKGEPGEKGMSGLPGDRGLR 950
Query: 291 EIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSP--ERGSPG 348
+ GA GP E ++ S+ G P + G PG
Sbjct: 951 GAK---------------------GAIGPPGDEGEMAII--SQKGTPGEPGPPGDDGFPG 987
Query: 349 RPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGW 408
+PG+ G PG P G G+ E + P GP G RG+
Sbjct: 988 ERGDKGTPGMQGRRGEPGRYGPP---GFHRGEPGEKG---QPGPPGPPGP-PGSTGLRGF 1040
Query: 409 TFAAALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRP-LPAAPGFSG 467
L P P S R P+ P P P PG G
Sbjct: 1041 IGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFG 1100
Query: 468 LCVLQPFPARSRGLGVPSQQGPTGS---PGCRDRASAPRAGAEAGSM-----ETFLRNGG 519
Q P G P + GP GS PGC P + G M + G
Sbjct: 1101 ASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPG 1160
Query: 520 LYPPPSPRAPA 530
+ PP + P+
Sbjct: 1161 IPGPPGIKGPS 1171
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/242 (26%), Positives = 74/242 (30%), Gaps = 37/242 (15%)
Query: 204 GP-GPRRGGGLTSAPPGLPP----LASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKE 258
GP GPR G PPGLP L P LP PP PP PPGP
Sbjct: 1267 GPDGPRGAPG----PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP-------------- 1308
Query: 259 VGLRPRTRGWTTCVVSPNLRRG---SRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLG 315
P +G+ C + G H L GP G
Sbjct: 1309 ----PGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRG 1364
Query: 316 AQGPRSSTPECPVVNGSEW--GLAAPLS----PERGSPGRPAFLRSPGLCGPGPVPGGLS 369
GP + +CP + G G+ P P P P PGL G V G
Sbjct: 1365 EPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPG 1424
Query: 370 VPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAA 429
P P GR GD E P G + G+ L + +Q P P
Sbjct: 1425 SPGPPGR-KGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLG 1483
Query: 430 SP 431
P
Sbjct: 1484 MP 1485
Score = 37.4 bits (85), Expect = 0.035
Identities = 94/385 (24%), Positives = 117/385 (30%), Gaps = 113/385 (29%)
Query: 186 GASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPA 245
G S + RG RGP G P G+P F L P P PPGP
Sbjct: 86 GLSGEKGMRGD------RGPPGAAGDKGDKGPTGVPG------FPGLDGIPGHPGPPGP- 132
Query: 246 LLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAG-----NHRVREIEFGSALLA 300
RGK P G P G G H + E G+++
Sbjct: 133 ---------RGK-----PGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFI 178
Query: 301 ALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPER-----------GSPGR 349
GA G QG R P P + GS WG P P G PGR
Sbjct: 179 ---------LGAVKGIQGDRGD-PGLPGLPGS-WGAGGPAGPTGYPGEPGLVGPPGQPGR 227
Query: 350 PAFLRSPGLC---------------GPGP--------------------VPGGLSVPTPC 374
P +PG+ PGP +PG + +P P
Sbjct: 228 PGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPP 287
Query: 375 GRG--AGDFSEADLADRAFPVRGAGP-------IAGRRRRRGWT-----FAAALRKGAP- 419
GR +G ++ + FP P G + G F KG P
Sbjct: 288 GRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPG 347
Query: 420 -REQP-PASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPAR 477
R P P +P + P + P G V P P PG G +P A
Sbjct: 348 NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP---PGPPGLLG----RPGEAC 400
Query: 478 SRGLGVPSQQGPTGSPGCRDRASAP 502
+ +G P QG G PG A P
Sbjct: 401 AGMIGPPGPQGFPGLPGLPGEAGIP 425
Score = 31.2 bits (69), Expect = 2.5
Identities = 80/314 (25%), Positives = 103/314 (32%), Gaps = 60/314 (19%)
Query: 198 PALIVRGPG-----PRRGGGLTSA-PPGLPPLASPP--PFWELPRPPPP------PPPPG 243
P L ++GP P R G PPG P L P + PP P P PG
Sbjct: 361 PPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPG 420
Query: 244 PALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALN 303
A +P R GK P G SP L G ++ + S + ++
Sbjct: 421 EAGIPGRPDSAPGK-----PGKPG------SPGL------PGAPGLQGLPGSSVIYCSVG 463
Query: 304 TLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGP 363
GP +G G R E G+E GL A G PG P G G
Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGE----KGNE-GLCACEPGPMGPPGPPGLPGRQGSKGDLG 518
Query: 364 VPGGLSVPTPCGRGAGDFSEADLADRAFPVR-GAGPIAGRRRRRGWTFAAALRKGAPREQ 422
+PG L G + P + GA G + +G + + KG E+
Sbjct: 519 LPGWLGTKGDPGPPGAE------GPPGLPGKHGASGPPGNKGAKGDMVVSRV-KGHKGER 571
Query: 423 PPASPAASPCQAPRAPEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVL--QPFPARSRG 480
P P P Q P GR + P PG + FP
Sbjct: 572 GPDGPPGFPGQ-----------PGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP--- 617
Query: 481 LGVPSQQGPTGSPG 494
LG P + GP G PG
Sbjct: 618 LGPPGKAGPVGPPG 631
Score = 30.4 bits (67), Expect = 4.3
Identities = 53/195 (27%), Positives = 61/195 (31%), Gaps = 28/195 (14%)
Query: 342 PERGSPGRPAFLRSPGLCGP-GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIA 400
PE+GS G PG GP GP+ G L P P G D RG A
Sbjct: 59 PEKGSRG------PPGPPGPQGPI-GPLGAPGPIGLSGEKGMRGD--------RGPPGAA 103
Query: 401 GRRRRRGWTFAAAL--RKGAPREQPPASPAASP-CQAPRAPEKETEAPRLRGRATAVAPR 457
G + +G T G P P P P + P RG P
Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163
Query: 458 PLPAAPGFSGLCVLQPFPARSRGLG-VPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLR 516
P G G V LG V QG G PG + AG AG
Sbjct: 164 GHPGEKGEKGNSVFI--------LGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGE 215
Query: 517 NGGLYPPPSPRAPAV 531
G + PP P P +
Sbjct: 216 PGLVGPPGQPGRPGL 230
Score = 30.0 bits (66), Expect = 5.6
Identities = 53/197 (26%), Positives = 66/197 (33%), Gaps = 21/197 (10%)
Query: 307 PGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCG----PG 362
PG FG +G +G + G L P P +G PG P F G G PG
Sbjct: 334 PGLFGL-IGPKGDPGNRGH----PGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPG 388
Query: 363 PVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQ 422
P PG L P G + FP G + G G +A + G P
Sbjct: 389 P-PGLLGRPGEACAG----MIGPPGPQGFP--GLPGLPGEAGIPGRPDSAPGKPGKPGSP 441
Query: 423 P-PASPAASPCQAPRAPEKETEAPRLRGRATAVAP---RPLPAAPGFSGLCVLQPFPARS 478
P +P P +G V P R G GLC +P P
Sbjct: 442 GLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGP 501
Query: 479 RG-LGVPSQQGPTGSPG 494
G G+P +QG G G
Sbjct: 502 PGPPGLPGRQGSKGDLG 518
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/280 (28%), Positives = 100/280 (35%), Gaps = 65/280 (23%)
Query: 205 PGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPP-----------GPALLPRRLRE 253
PGP G L P PPL PPP + PPPPPPPP P LP
Sbjct: 687 PGPPVVGAL-QPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPP 745
Query: 254 LRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGP----GS 309
V + P T + PNL G+R +GSA+ A T P
Sbjct: 746 PITPPVSIPP---PHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802
Query: 310 FGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGS-PGRPAFLRSPGL---------- 358
+ LG QG V G GL AP + G+ PG R PG+
Sbjct: 803 PVSLLGTQG---------VAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPL 853
Query: 359 ------------CGPGPVPGGLSVPTPCG-RGAGDFSEADLADRAFP-VRGAGPIAGRRR 404
GP P PGG ++P P G +G + P + G GP G
Sbjct: 854 MPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPE 913
Query: 405 RRGWTFAAALRKGAPREQPPASPAASP-CQAPRAPEKETE 443
R R+QPP P P QAP+ P+++ +
Sbjct: 914 DRD-----------GRQQPPQQPQQQPQPQAPQQPQQQQQ 942
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 52.4 bits (124), Expect = 1e-06
Identities = 86/357 (24%), Positives = 117/357 (32%), Gaps = 72/357 (20%)
Query: 217 PPGLPPLASPPPFWELPRPPPP-PPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSP 275
PP PPL PPP P PPPP PP R + +G+ L +G V+
Sbjct: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
Query: 276 NLRRGSRRAGNHRVREIEFGSAL------------------LAALNTLGPGSFGAGLGAQ 317
R + + + + E G + L G G Q
Sbjct: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQ 124
Query: 318 GPRSSTPECPVVNGSEWG-LAAPLSPERG-----------SPGRPAFLRSPGLCG----- 360
GP S P + N + G L P SP G +P RP P
Sbjct: 125 GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP 184
Query: 361 --PGPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGA 418
P P+P + TP G ++ +L A PV A P
Sbjct: 185 PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP-------------------- 224
Query: 419 PREQPPASPAASPCQAPRAPEKETEA--PRLRGRATAVAPRPLPAAP--GFSGLCVLQPF 474
PP P +P P A +A P+L P PLP P G+ GL
Sbjct: 225 ---PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS 281
Query: 475 PARSRGLGVPSQQGPTGSPGCRDRAS-APRAGAEAGSMETFLRNGGLYPPPSPRAPA 530
PA+ +Q+ P P AS +PRA A + + PP P++P+
Sbjct: 282 PAQD------AQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPS 332
Score = 43.9 bits (102), Expect = 4e-04
Identities = 113/478 (23%), Positives = 150/478 (31%), Gaps = 139/478 (29%)
Query: 67 SAPPAATDAAHMSASTGTEVQMKRVGPKSWAP-------APRRQRASSAQVRAARPAGMA 119
SAPP +TD + ++R PK + R ++ + R+A +
Sbjct: 27 SAPPVSTDTS----------SLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESS 76
Query: 120 AGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRCGARA 179
GT + G GSA G+ P LG LF +G R G +
Sbjct: 77 KGTNKEGGGSANTR-GASTPPT----------LGD-LFAGGFPVLRPAGQ--RDVAGGKT 122
Query: 180 FYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPP 239
A S R ++ PR G TS G A P P +P PPPP
Sbjct: 123 GQGPGSRAPSPRLPNKTISGPLIPPASPRLGN--TSEAHGAARTAPPRP--NVPAPPPPT 178
Query: 240 PPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALL 299
PPP P LP L P + T +VSP G GN
Sbjct: 179 PPPPPPPLPPPL-----------PSSSPIKTPLVSP---PGPLTKGN------------- 211
Query: 300 AALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLC 359
L + P P P P P P P PA + S
Sbjct: 212 --LPVVAP-----------PVPCAPPPP----------PPPPPPTPPPLPPASVLSDKAV 248
Query: 360 GP-------GPVPGGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAA 412
P P+P L + PCG +P A P +
Sbjct: 249 KPQLAPLHLPPIPPPLPLLPPCG---------------YPGLKAEPA-----------SP 282
Query: 413 ALRKGAPREQPPASPAASPCQAPRAPEKETEAPRLRG-RATAVAPRPL-PAAPGFSGLCV 470
A P PP P + C +P AP L G +++ P PL P +P F
Sbjct: 283 AQDAQEPPAPPPPLPPYASC----SPRASLPAPPLPGVNSSSETPPPLPPKSPSF----- 333
Query: 471 LQPFPARSRGLGVPSQQGPTGSPGCRDRASAPRAGAEAGSMETFLRNGGLYPPPSPRA 528
Q P ++ +P+ P GS + R GA G L PPP+P A
Sbjct: 334 -QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK---------LNPPPAPPA 381
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 52.4 bits (124), Expect = 1e-06
Identities = 129/546 (23%), Positives = 169/546 (30%), Gaps = 134/546 (24%)
Query: 66 SSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRS 125
S P A + + H SA G G S PA R + AA +G GR
Sbjct: 1056 SPTPGAPSPSHHGSAGGG--------GGSSQGPALRYFQLPPRAASAAMYVPARSGRGRK 1107
Query: 126 GPGSARL----------GLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPHCRLRC 175
GP + GL P +P+ A+ A ++ +
Sbjct: 1108 GPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTI--------- 1158
Query: 176 GARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPPGLPPLASPPPFWELPRP 235
A + +S R Q A P P GGG + P P SP P P P
Sbjct: 1159 ---IIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP--PSPSP 1213
Query: 236 -PPPPPPPGPALLPRRLRELRGKEVGLRPRTRGW-------TTCVVSPN----------- 276
P P P GPA L + VG R GW +T +S +
Sbjct: 1214 VPTPASPSGPATLD-FTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGL 1272
Query: 277 ---LRRGSRRAGNHRVREIEFGSALLAALNTLGPG-----------SFGAGLGAQGPRSS 322
G R + + E F + L + G G ++G G G+ S
Sbjct: 1273 GTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSF 1332
Query: 323 TPECPVVN---GSEWGLAAPL--------------SPERGSPGRPAFLRSPGLCGPGPVP 365
P P+V+ G A+PL S G+P P SP P P P
Sbjct: 1333 LPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTP 1392
Query: 366 ---------------GGLSVPTPCGRGAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTF 410
G S P P R G + +++ P A P A RR
Sbjct: 1393 HHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLP---ASPPAARR------- 1442
Query: 411 AAALRKGAPREQPPASPAASPC-----QAPRAPEKETEAPRLRGRATAVAPRPLPAAPGF 465
PP +P P P AP P A P LP F
Sbjct: 1443 ------SLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKP--WRSAAPEEPERLPLHVRF 1494
Query: 466 SGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRA-----SAPRAGAEAGSMETFLRNGGL 520
C QP + G G PS+ GP P R+ ++PRA E G L
Sbjct: 1495 LENC--QPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVL----- 1547
Query: 521 YPPPSP 526
PPP+P
Sbjct: 1548 -PPPAP 1552
Score = 41.2 bits (95), Expect = 0.002
Identities = 71/249 (28%), Positives = 98/249 (39%), Gaps = 63/249 (25%)
Query: 217 PPGLPPLASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKEVGLRPRTRGWTTCVVSPN 276
PPG P A+P P P+P P PPP G + G+
Sbjct: 1647 PPGPPAPAAPAP--AAPQPGPDPPP--------------GTDSGIE-------------- 1676
Query: 277 LRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPE-----CPVVNG 331
SR + +H + I S L ++L+ G GS G G GA +S PE ++G
Sbjct: 1677 -EVDSRSSSDHPLETISSASTL-SSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDG 1734
Query: 332 SEWGLAA----PLSPERGSPG--RPAFLRSPGLCGPGPVPGGL------SVPTPCGRGAG 379
+G ++ P P+ +P R L + G PGP GGL + PT GAG
Sbjct: 1735 QAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP-SGGLRDPVTPTSPTVSVTGAG 1793
Query: 380 DFSEADLADRAF---PVRG--AGPIAGRRRRRGW---TFAAALRKGAPREQ---PPASPA 428
++ LA RA P G GP+A T ++ RK P E+ PP P
Sbjct: 1794 --TDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPL 1851
Query: 429 ASPCQAPRA 437
P P+A
Sbjct: 1852 PGPLAQPQA 1860
Score = 38.5 bits (88), Expect = 0.016
Identities = 56/219 (25%), Positives = 79/219 (36%), Gaps = 49/219 (22%)
Query: 67 SAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSG 126
+AP A GT+ ++ V +S + P +S++ + + G G G
Sbjct: 1654 AAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEG---GGSAGG 1710
Query: 127 PGSARLGLGSGWDPARAVAPRAARALGAALFGRAVHTAALSGPH--------CRLRCGAR 178
G A G+ SG P A L G+A ++ GP +LR R
Sbjct: 1711 GGGAGAGVASG--------PELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLR--GR 1760
Query: 179 AFYAAAG---GASSRRRQ--RGRNPALIVRGPG-------------PRRG--GGLTSAPP 218
A A+ G G S R +P + V G G P G GG + P
Sbjct: 1761 ALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEP 1820
Query: 219 GLPPLASPPPF--------WELPRPPPPPPPPGPALLPR 249
+PP+ P WE PPPPP PGP P+
Sbjct: 1821 EVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQ 1859
Score = 38.1 bits (87), Expect = 0.020
Identities = 136/573 (23%), Positives = 179/573 (31%), Gaps = 99/573 (17%)
Query: 7 PGCLRPPPARASPAPGSSV---LWLSQRPSLAVSSRMVSFWLRMVSFCCSTVSRSCSTLL 63
P +PPPA A+P+ +S+ + + PS + S R S+ ST
Sbjct: 1135 PASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRS---------------SQGSSTEA 1179
Query: 64 RSSSAPPAATDAAHMSASTGTEVQMKRVGPKSWAPAPRRQRAS------------SAQVR 111
+ P +S M V P S +P P S +A V
Sbjct: 1180 EPPTQPEPTGGGGGGGSSPSPAPAMSPV-PPSPSPVPTPASPSGPATLDFTSQFGAALVG 1238
Query: 112 AARPAG-------------MAAGTGRSGPGSARLGLGSGWDPARAVAPRAARALGAALFG 158
AAR G ++ G G LG G+ P + + +A
Sbjct: 1239 AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPY 1298
Query: 159 RAVHTAALSGPHCRLRCGARAFYAAAGGASSRRRQRGRNPALIVRGPGPRRGGGLTSAPP 218
+ +A + G+RA Y GG+S+ P + P G L A P
Sbjct: 1299 LRLESAGSGAGYGGYGAGSRA-YGGGGGSSAFTSFLPPRPLV-----HPLTGKALDPASP 1352
Query: 219 -GLPPLASPPPFWELPR----PPPPPPPPGPAL-LPRRLRELRGKEVGLRPRTRGWTTCV 272
GL A E P PPP PP P P P R W
Sbjct: 1353 LGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASP 1412
Query: 273 VSPNLRRGSRRAG---NHRVREIEFGSALLAALNTLGPGSFGAG--LGAQGPRSSTPECP 327
P R RAG + +A + L+ L P + G G L G P
Sbjct: 1413 PDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPG 1472
Query: 328 VVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGP-GPVPGGLSVPTPCGRGAGDFSEADL 386
V W AAP PER P +R C P PV G P+ G G S
Sbjct: 1473 V--SKPWRSAAPEEPER----LPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPR-- 1524
Query: 387 ADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPR------EQPPASPAASPCQAPRAPEK 440
R+ P P + R L AP E P P + + EK
Sbjct: 1525 --RSVP---PSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEK 1579
Query: 441 ETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCRDRAS 500
E+P G + P PA P L P P + P+ S D
Sbjct: 1580 -PESPLTPGPPHPLPDTPAPATP-------LPPVPPPAVAAAPPTLDSTASSLTSYDSEV 1631
Query: 501 AP-RAGAEAGSMETFLRNGGLYP--PPSPRAPA 530
A GA A G +P PP+P APA
Sbjct: 1632 ATLTQGASAAP-------GDPHPPGPPAPAAPA 1657
Score = 29.3 bits (64), Expect = 9.5
Identities = 58/259 (22%), Positives = 86/259 (33%), Gaps = 46/259 (17%)
Query: 220 LPPLASPPPFWELPRPPPPPP------PPGPALL---------PRRLRELRGKEVGLRPR 264
LPP PP PPP P PP P + P RL +G +P
Sbjct: 993 LPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRL------ALGPQPS 1046
Query: 265 TRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTP 324
RGW SP G+ +H GSA ++ GP L PR+++
Sbjct: 1047 LRGWRGGGPSPT--PGAPSPSHH-------GSAGGGGGSSQGPALRYFQL---PPRAASA 1094
Query: 325 ECPVVNGSEWGLAAPLSPERGSPGRPAFLRSPGLCGPGPVPGGLSVPTPCGRGAGDFSEA 384
V S G PL + G P + G P P P + P P A +
Sbjct: 1095 AMYVPARSGRGRKGPLVKQTKVEGEP---QKGGGLPPAPSPTSPASPQPPPAVAAPSEKN 1151
Query: 385 DLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPRAPEKETEA 444
+ ++ + R +G ++ P + P +P + A
Sbjct: 1152 SIPIPTIIIKAPSTSSSGRSSQG----SSTEAEPPTQPEPTGGGGGGGSSP------SPA 1201
Query: 445 PRLRGRATAVAPRPLPAAP 463
P + + +P P PA+P
Sbjct: 1202 PAMSPVPPSPSPVPTPASP 1220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,687,528
Number of Sequences: 37866
Number of extensions: 2362175
Number of successful extensions: 41495
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 573
Number of HSP's successfully gapped in prelim test: 1466
Number of HSP's that attempted gapping in prelim test: 18109
Number of HSP's gapped (non-prelim): 13697
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.