Guide to the Human Genome
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Name: LPA Sequence: fasta or formatted (2040aa) NCBI GI: 116292750
Description:

lipoprotein Lp(a) precursor

Referenced in:

Coagulation
Lipoproteins
Polymorphism
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5        133           2
 C cysteine            5.3        109           1
 D aspartate           3.2         66           1
 E glutamate           6.1        124           2
 F phenylalanine       0.9         19           2
 G glycine             6.8        138           2
 H histidine           2.8         57           1
 I isoleucine          1.8         37           1
 K lysine              1.2         25           2
 L leucine             4.0         82           5
 M methionine          1.9         38           2
 N asparagine          4.4         89           2
 P proline            10.0        203           2
 Q glutamine           4.9        100           1
 R arginine            5.9        120           2
 S serine              8.2        167           3
 T threonine          11.1        227           2
 V valine              6.1        124           2
 W tryptophan          2.5         51           1
 Y tyrosine            6.4        131           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lipoprotein Lp(a) precursor 
PLG                   0.238   plasminogen 
MST1                  0.099   macrophage stimulating 1 (hepatocyte growth factor-...
HGF                   0.096   hepatocyte growth factor isoform 1 preproprotein [Ho...
HGF                   0.094   hepatocyte growth factor isoform 3 precursor 
LOC100289195          0.061   PREDICTED: hypothetical protein XP_002342719 
F2                    0.048   coagulation factor II preproprotein 
PLAT                  0.048   plasminogen activator, tissue isoform 1 preproprotein...
PLAT                  0.048   plasminogen activator, tissue isoform 3 preproprotei...
LPAL2                 0.042   lipoprotein, Lp(a)-like 2 precursor 
LPAL2                 0.042   lipoprotein, Lp(a)-like 2 precursor 
HABP2                 0.037   hyaluronan binding protein 2 preproprotein 
HGFAC                 0.036   HGF activator preproprotein 
HGF                   0.036   hepatocyte growth factor isoform 2 precursor 
OVCH1                 0.035   ovochymase 1 
TMPRSS13              0.034   transmembrane protease, serine 13 
HGF                   0.034   hepatocyte growth factor isoform 4 precursor 
TPSG1                 0.034   transmembrane tryptase preproprotein 
PRSS27                0.033   marapsin 
PRSS33                0.033   protease, serine, 33 
TMPRSS3               0.033   transmembrane protease, serine 3 isoform 1 
HPN                   0.033   hepsin 
HPN                   0.033   hepsin 
PLAU                  0.033   plasminogen activator, urokinase isoform 2 
PLAU                  0.033   plasminogen activator, urokinase isoform 1 preproprot...
TMPRSS2               0.032   transmembrane protease, serine 2 isoform 1 
TMPRSS2               0.032   transmembrane protease, serine 2 isoform 2 
CTRB1                 0.032   chymotrypsin B1 
PRSS21                0.032   testisin isoform 2 
PRSS21                0.032   testisin isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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