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Search of human proteins with 221316760
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316760 L1 cell adhesion molecule isoform 3 precursor
[Homo sapiens]
(1248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 2559 0.0
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 2551 0.0
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 2546 0.0
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 918 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 838 0.0
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 770 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 732 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 732 0.0
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 723 0.0
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 624 e-178
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 459 e-129
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 455 e-127
gi|75709184 contactin 3 [Homo sapiens] 409 e-114
gi|7657359 contactin 5 isoform long [Homo sapiens] 404 e-112
gi|28373129 contactin 5 isoform short [Homo sapiens] 404 e-112
gi|4827022 contactin 2 precursor [Homo sapiens] 386 e-107
gi|7657361 contactin 6 [Homo sapiens] 384 e-106
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 383 e-106
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 345 2e-94
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 344 3e-94
gi|119220552 sidekick 1 [Homo sapiens] 260 7e-69
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 259 1e-68
gi|222352127 sidekick 2 [Homo sapiens] 248 3e-65
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 243 1e-63
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 231 2e-60
gi|157311649 neogenin homolog 1 [Homo sapiens] 229 2e-59
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 205 3e-52
gi|4506569 roundabout 1 isoform a [Homo sapiens] 204 6e-52
gi|19743806 roundabout 1 isoform b [Homo sapiens] 203 7e-52
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 201 4e-51
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 2559 bits (6632), Expect = 0.0
Identities = 1248/1248 (100%), Positives = 1248/1248 (100%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEV 60
MVVALRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEV
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEV 60
Query: 61 QFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMS 120
QFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMS
Sbjct: 61 QFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMS 120
Query: 121 HEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERV 180
HEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERV
Sbjct: 121 HEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERV 180
Query: 181 TMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFP 240
TMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFP
Sbjct: 181 TMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFP 240
Query: 241 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 300
TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE
Sbjct: 241 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 300
Query: 301 DDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT 360
DDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT
Sbjct: 301 DDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT 360
Query: 361 WRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLP 420
WRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLP
Sbjct: 361 WRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLP 420
Query: 421 AKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIR 480
AKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIR
Sbjct: 421 AKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIR 480
Query: 481 DLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDP 540
DLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDP
Sbjct: 481 DLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDP 540
Query: 541 SLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQ 600
SLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQ
Sbjct: 541 SLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQ 600
Query: 601 LLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL 660
LLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL
Sbjct: 601 LLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL 660
Query: 661 GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEG 720
GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEG
Sbjct: 661 GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEG 720
Query: 721 NETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYE 780
NETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYE
Sbjct: 721 NETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYE 780
Query: 781 IKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHL 840
IKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHL
Sbjct: 781 IKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHL 840
Query: 841 RGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP 900
RGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP
Sbjct: 841 RGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP 900
Query: 901 ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQ 960
ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQ
Sbjct: 901 ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQ 960
Query: 961 LSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1020
LSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA
Sbjct: 961 LSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1020
Query: 1021 TAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTD 1080
TAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTD
Sbjct: 1021 TAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTD 1080
Query: 1081 YEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKR 1140
YEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKR
Sbjct: 1081 YEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKR 1140
Query: 1141 SKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGSDDSLA 1200
SKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGSDDSLA
Sbjct: 1141 SKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGSDDSLA 1200
Query: 1201 DYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1248
DYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1201 DYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1248
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 2551 bits (6613), Expect = 0.0
Identities = 1247/1253 (99%), Positives = 1248/1253 (99%), Gaps = 5/1253 (0%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEE-----LMEPPVITEQSPRRLVVFPTDDISLKCEAS 55
MVVALRYVWPLLLCSPCLLIQIPEE +MEPPVITEQSPRRLVVFPTDDISLKCEAS
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
Query: 56 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 115
GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 116 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 175
GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
Query: 176 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 235
QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP
Sbjct: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
Query: 236 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 295
RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL
Sbjct: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
Query: 296 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 355
KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP
Sbjct: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
Query: 356 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 415
QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY
Sbjct: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 416 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 475
VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG
Sbjct: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
Query: 476 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 535
TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
Query: 536 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 595
ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV
Sbjct: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
Query: 596 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 655
ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE
Sbjct: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
Query: 656 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 715
KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD
Sbjct: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
Query: 716 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 775
VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST
Sbjct: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
Query: 776 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 835
FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 836 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 895
VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 896 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE
Sbjct: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1015
GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1016 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1075
GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL
Sbjct: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1076 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1135
QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL
Sbjct: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
Query: 1136 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGS 1195
CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGS
Sbjct: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGS 1200
Query: 1196 DDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1248
DDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1201 DDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1253
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 2546 bits (6598), Expect = 0.0
Identities = 1247/1257 (99%), Positives = 1248/1257 (99%), Gaps = 9/1257 (0%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEE-----LMEPPVITEQSPRRLVVFPTDDISLKCEAS 55
MVVALRYVWPLLLCSPCLLIQIPEE +MEPPVITEQSPRRLVVFPTDDISLKCEAS
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
Query: 56 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 115
GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 116 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 175
GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
Query: 176 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 235
QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP
Sbjct: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
Query: 236 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 295
RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL
Sbjct: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
Query: 296 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 355
KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP
Sbjct: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
Query: 356 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 415
QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY
Sbjct: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 416 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 475
VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG
Sbjct: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
Query: 476 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 535
TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
Query: 536 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 595
ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV
Sbjct: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
Query: 596 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 655
ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE
Sbjct: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
Query: 656 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 715
KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD
Sbjct: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
Query: 716 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 775
VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST
Sbjct: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
Query: 776 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 835
FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 836 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 895
VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 896 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE
Sbjct: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1015
GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1016 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1075
GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL
Sbjct: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1076 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1135
QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL
Sbjct: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
Query: 1136 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY----SDNEEKAFGSSQPSLNGDIK 1191
CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY SDNEEKAFGSSQPSLNGDIK
Sbjct: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK 1200
Query: 1192 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1248
PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1201 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1257
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 918 bits (2373), Expect = 0.0
Identities = 510/1290 (39%), Positives = 733/1290 (56%), Gaps = 70/1290 (5%)
Query: 11 LLLCSPCLLIQIP------EELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 64
L LC +++P E+L++PP IT+QSP+ ++ P ++I ++CEA GKP F W
Sbjct: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
Query: 65 TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIR 124
TR+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I
Sbjct: 81 TRNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIV 138
Query: 125 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 184
+ +P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G
Sbjct: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
Query: 185 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------ 232
NG+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 199 NGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY 258
Query: 233 -------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY 285
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y
Sbjct: 259 GAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318
Query: 286 QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETA 345
+N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
Query: 346 RLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRH 405
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +
Sbjct: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
Query: 406 GLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQ 465
G LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L
Sbjct: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
Query: 466 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 525
++ + + NGTL I Q + TG Y C+A N +L++KD T I + P + +
Sbjct: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
Query: 526 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYS 585
+GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+
Sbjct: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYT 615
Query: 586 CVASTELDVVESRAQLLVVGSPGPVPRLVLS------DLHLLTQ--SQVRVSWSPAEDHN 637
CVA+T LD V + A L VV +P P P V DL L Q V++SW+P +D+N
Sbjct: 616 CVANTTLDSVSASAVLSVV-APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
Query: 638 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 697
+PI K+ IE+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS
Sbjct: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
Query: 698 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 757
SE +T + P+KNP V+G G+E N+VITWKPL + N P +QY+V WR +
Sbjct: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
Query: 758 WQEQIVSD-PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 816
W +V++ +VS T TFVPY IKVQA+N G PEP V +G+SGED P P +
Sbjct: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
Query: 817 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 876
++NS+ V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +
Sbjct: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
Query: 877 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQP 935
L GL P+S Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W P
Sbjct: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
Query: 936 PLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKE 994
P NG+LT Y L Y P++ + +L+ P +T L +L+ RY+F A T
Sbjct: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
Query: 995 GPGEAIVREG-GTMALSGI--SDFG------------NISATAGENYSVVSWVPKEGQCN 1039
G G I E T+ +GI D G N++A A E Y+ +SW EG +
Sbjct: 1035 GSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW-EYEGPEH 1093
Query: 1040 FRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHL--FKERMFRHQMAV 1097
F++ + G ++ + V+ ++S + L P T Y++ + + F V
Sbjct: 1094 VNFYVEYGVAGSKE---EWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
Query: 1098 KTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVD 1157
G + AT+GWFIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D
Sbjct: 1151 FETGPA-MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHAD 1209
Query: 1158 SEARPMK--DETFGEYSDNEEK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNE 1212
E +PMK D TFGEYSD E+ GS PS + +K SDDSL DYG V+ QFNE
Sbjct: 1210 PEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNE 1268
Query: 1213 DGSFIGQYSGKKEKEAAGGNDSSGATSPIN 1242
DGSFIGQYSGKKEKE A GN+SS A SP+N
Sbjct: 1269 DGSFIGQYSGKKEKEPAEGNESSEAPSPVN 1298
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 838 bits (2165), Expect = 0.0
Identities = 478/1254 (38%), Positives = 680/1254 (54%), Gaps = 88/1254 (7%)
Query: 20 IQIPEELMEPPVITEQSPRRLVVFPTDD-ISLKCEASGKPEVQFRWTRDGVHFKPKEELG 78
I+IP + + P I +QS + V FP D+ ++CEA G PE F WT+DG F +
Sbjct: 25 IEIPSSVQQVPTIIKQSKVQ-VAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDH-- 81
Query: 79 VTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETV 138
+ S +SG+F I N FQG YRCFASNKLG AMS EI + PK+PKE +
Sbjct: 82 -RIIPSNNSGTFRIP--NEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKI 138
Query: 139 KPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDN 198
P+EVEEG+ +VLPCNPP PL IYWMN ++ HI+QDERV M Q G+LYFANV D+
Sbjct: 139 DPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDS 198
Query: 199 HSDYICHAHFPGTRTIIQKEPIDLRVKA----------------TNSMIDRKPRLLFP-- 240
+DY C A FP RTI+QK P+ L V + NS+ RKP+LL P
Sbjct: 199 RNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPT 258
Query: 241 -TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE 299
+ S S + L+G+ L+LEC AEG PTP + W + G +P R T +N+ KTL++ V
Sbjct: 259 ESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVSY 318
Query: 300 EDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEV 359
+D G YRC A N LG+A H ++V VE P W KPQS +Y G L C+ +G PQP +
Sbjct: 319 QDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTI 378
Query: 360 TWRINGIPVEE--LAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV 417
WR+NG PV+ A D + + + +N+QP+ T V QCEA N HG +LANA I VV
Sbjct: 379 KWRVNGSPVDNHPFAGDVVFPRE---ISFTNLQPNHTAVYQCEASNVHGTILANANIDVV 435
Query: 418 QLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTL 477
+ I T D + Y V G +A+L C+ F +P V W + L+ R+ Y NGTL
Sbjct: 436 DVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTL 495
Query: 478 GIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQAS 537
I D G Y C N + ANL +++AT++ P++ K + C++
Sbjct: 496 QINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESK 555
Query: 538 FDPSLQPSI--TWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQGNYSCVASTELDV 594
D L+ S+ +W DG + G D I DG L I ++ DQG Y C A T LD
Sbjct: 556 CDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDS 615
Query: 595 VESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP 654
Q+ V+ P P L LS+ VR++W DHN+ I +Y +EFE + P
Sbjct: 616 AADITQVTVLDVPDPPENLHLSERQ---NRSVRLTWEAGADHNSNISEYIVEFEGNKEEP 672
Query: 655 EKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPV 714
+W L +V G +T+ L L+P+V Y FRV A+N+ G +PS S+ TP AAP++NP
Sbjct: 673 GRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQ 732
Query: 715 DVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTS 774
+++ + ++ M+I W+PL+ M+ N P ++YRV W+PQG W+E+ V++ L V +
Sbjct: 733 NIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMTPA 792
Query: 775 TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA 834
+ PY++KVQA+N G GP+PQ YSGEDYP P + G++++NS+ V V W V
Sbjct: 793 VYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKD 852
Query: 835 QVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN 894
+V G L+GY + +W+ S + + S ++ L +S +HL V A+N
Sbjct: 853 RVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYN 912
Query: 895 GRGSGPASE-FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 953
+G+GP SE + F TPEGVP P L + + L W P NG LTGY+L Y +
Sbjct: 913 SKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQII 972
Query: 954 DEGGK-GQLS-FNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSG 1011
++ + G+L+ N+ P + +L++L+ +Y+F L+A T +G G+ I E T+ G
Sbjct: 973 NDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESSTLG-EG 1031
Query: 1012 ISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYT 1071
G IS V+ Q ++
Sbjct: 1032 SKGIGKISG------------------------------------------VNLTQKTHP 1049
Query: 1072 QWDLQPDTDYEIHLFKERMFRH----QMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIIL 1127
+P ++ + L + + Q ++T G L +T+GWFIG + AI L
Sbjct: 1050 IEVFEPGAEHIVRLMTKNWGDNDSIFQDVIETRGREYAGLYD-DISTQGWFIGLMCAIAL 1108
Query: 1128 LLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLN 1187
L L+LL +CF+KR++GGKYSVK+KED D E + +KDETFGEYSD++EK S SLN
Sbjct: 1109 LTLLLLTVCFVKRNRGGKYSVKEKEDLHPDPEIQSVKDETFGEYSDSDEKPLKGSLRSLN 1168
Query: 1188 GDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPI 1241
D++P S DSL +YG F+EDGSFIG Y+G KEK + N SS AT P+
Sbjct: 1169 RDMQPTESADSLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPL 1222
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 770 bits (1988), Expect = 0.0
Identities = 398/1018 (39%), Positives = 583/1018 (57%), Gaps = 30/1018 (2%)
Query: 11 LLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVH 70
L LC +++P +L++PP IT+QSP+ ++ P ++I ++CEA GKP F WTR+G H
Sbjct: 21 LFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTH 80
Query: 71 FKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGA 130
F ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I + +
Sbjct: 81 FDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRS 138
Query: 131 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 190
P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G NG+LYF
Sbjct: 139 PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYF 198
Query: 191 ANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------------ 232
+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 199 SNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSR 258
Query: 233 -RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 291
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y+N KT
Sbjct: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
Query: 292 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQV 351
LQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE L C+
Sbjct: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRA 378
Query: 352 QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLAN 411
G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +G LLAN
Sbjct: 379 NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLAN 438
Query: 412 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP 471
A++ V+ P +ILT N Y + A L C FG+P+P+++W + L ++ +
Sbjct: 439 AFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 498
Query: 472 YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVT 531
+ NGTL I Q + TG Y C+A N +L++KD T I + P + ++GS V+
Sbjct: 499 HENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVS 558
Query: 532 FTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTE 591
F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+CVA+T
Sbjct: 559 FECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTT 615
Query: 592 LDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKE 651
LD V + A L VV P P L L+D V++SW+P +D+N+PI K+ IE+ED
Sbjct: 616 LDSVSASAVLSVVDVPNPPFDLELTD---QLDKSVQLSWTPGDDNNSPITKFIIEYEDAM 672
Query: 652 MAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEK 711
P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS SE +T + P+K
Sbjct: 673 HKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
Query: 712 NPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD-PFLVV 770
NP V+G G+E N+VITWKPL + N P +QY+V WR + W +V++ +V
Sbjct: 733 NPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIV 792
Query: 771 SNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRP 830
S T TFVPY IKVQA+N G PEP V +G+SGED P P + ++NS+ V W P
Sbjct: 793 SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDP 852
Query: 831 VDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEV 890
V L ++GHL+GY + YW+ S K ++RHI K + + T +L GL P+S Y L V
Sbjct: 853 VPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNV 912
Query: 891 QAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS 949
+ NG+G GPAS + F+TPEGVP P +L + + SL L W PP NG+LT Y L
Sbjct: 913 RVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLK 972
Query: 950 YHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKEGPGEAIVREGGT 1006
Y P++ + +L+ P +T L +L+ RY+F A T G G I E T
Sbjct: 973 YQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVT 1030
Score = 238 bits (608), Expect = 2e-62
Identities = 307/1210 (25%), Positives = 482/1210 (39%), Gaps = 152/1210 (12%)
Query: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
E+ L P +++ K ++ E++V+ C P + N I +D VT
Sbjct: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
Query: 182 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA-TNSMIDRKPRLLFP 240
M N+++ Y + Q + R A +N+++ R R
Sbjct: 91 MKPGTGTLIINIMSEGKAETY---------EGVYQCTARNERGAAVSNNIVVRPSRSPLW 141
Query: 241 TNSSSHLVALQ-GQPLVLECIAE-GFPTPTIKWLRPSGP-MPADRVTYQNHNKTLQLLKV 297
T + LQ GQ LVL C G P P I W+ S +P Q N L V
Sbjct: 142 TKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNV 201
Query: 298 GEEDDGE-YRCLAE-NSLGSARHAYYVTVEA---------------------APYWLHKP 334
ED E Y C A N + + ++V+ A +P
Sbjct: 202 LPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERP 261
Query: 335 QSHLYGPGETAR----------LDCQVQGRPQPEVTW-RINGIPVEELAKDQK-YRIQRG 382
+ L G + L+C +G P P + W + +G+ L K++ Y+
Sbjct: 262 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEK 317
Query: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
L + +V +D+ QC A+N G + + V P I N + G L+
Sbjct: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN--LVLSPGEDGTLI 375
Query: 443 CKAFGAPVPSVQWLDED-GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 501
C+A G P P + WL + D+ T+ ++Q + Y C A+N+ +
Sbjct: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
Query: 502 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG 559
A + V P +T+ + + +F S P+I W G L E
Sbjct: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-- 493
Query: 560 DSDKYFI-EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 618
D Y + E+G L I G Y+CVA +L + ++ L + +V
Sbjct: 494 --DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW----IVKQPE 547
Query: 619 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFED-KEMAPEKWYSLGKVPGNQTSTTLKLSPY 677
+ + Q VS+ H+ + + +D +E+ ++ +++ K +S
Sbjct: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK----DHLVVADVSDD 603
Query: 678 VHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD 737
T+ A S V V P P D++ ++ ++W P D
Sbjct: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNP-----PFDLELTDQLDKSVQLSWTP--GDD 656
Query: 738 WNAPQVQYRVQWRPQGTR-GPW--QEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG-- 792
N+P ++ +++ + G W Q ++ S +V Y +V AVNS GK
Sbjct: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
Query: 793 ---PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 849
E +T + P A+ L G E N +++ W+P++ + G Y V++ +
Sbjct: 717 SEASEQYLTKASEPDKNPTAVEGL-GSEPDN---LVITWKPLNGFESNGPGLQYKVSWRQ 772
Query: 850 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 909
+ + + VV AN + I+SG + Y ++VQA N G P P
Sbjct: 773 KDGDDEWTS--------VVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE-------P 817
Query: 910 EGVPGH---------PEALHLECQSNTSLLLRWQP-PL-SHNGVLTGYVLSYHPLDEGGK 958
V GH P + + ++T + W P PL S G L GY + Y K
Sbjct: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
Query: 959 GQLSFNLRDPELR--------THN-LTDLSPHLRYRFQLQATTKEGPGEAI------VRE 1003
N R E + TH L L P Y ++ +G G A E
Sbjct: 878 R----NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 933
Query: 1004 GGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNF--RFHILFKALGEEKGGASLSPQ 1061
G A S + ++ T + W P + + ++ + L
Sbjct: 934 GVPSAPSSLKI---VNPTLDS--LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
Query: 1062 YVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAG----FATEGW 1117
+ N++ +T +L T Y+ + + + + V A AT+GW
Sbjct: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
Query: 1118 FIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMK--DETFGEYSDNE 1175
FIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D E +PMK D TFGEYSD E
Sbjct: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
Query: 1176 EK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGN 1232
+ GS PS + +K SDDSL DYG V+ QFNEDGSFIGQYSGKKEKE A GN
Sbjct: 1109 DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGN 1167
Query: 1233 DSSGATSPIN 1242
+SS A SP+N
Sbjct: 1168 ESSEAPSPVN 1177
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 732 bits (1889), Expect = 0.0
Identities = 392/1010 (38%), Positives = 556/1010 (55%), Gaps = 31/1010 (3%)
Query: 17 CLL-----IQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHF 71
CLL I+IP +L +PP IT+QS + +V P D+I ++CEA G P F WTR+ F
Sbjct: 17 CLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF 76
Query: 72 KPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P
Sbjct: 77 NIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 132 KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFA 191
WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 192 NVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------SMIDRK 234
NV+ D +DY C+A F T TI QK P L+V + + +R
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 235 PRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQL 294
P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++
Sbjct: 255 PSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRI 314
Query: 295 LKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGR 354
V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G
Sbjct: 315 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGN 374
Query: 355 PQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
P+P V W +NG P++ + + +I + Q S V QC N HG LLANA++
Sbjct: 375 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 434
Query: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYAN 474
V+ +P ++L+ NQ + + L C FG+P+P+++W + L + Y N
Sbjct: 435 SVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
Query: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
G+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+ V C
Sbjct: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLEC 554
Query: 535 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDV 594
+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVASTELD
Sbjct: 555 RVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 595 VESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP 654
++A L V+G P L L+D L + VR++W P + +N+PI Y ++FE+ + P
Sbjct: 612 DLAKAYLTVLGRPDRPRDLELTD---LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQP 668
Query: 655 EKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPV 714
W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A PE NP
Sbjct: 669 GVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPG 728
Query: 715 DVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTS 774
DVKGEG NM ITW P+ P ++Y V+WR + TR W V VV T
Sbjct: 729 DVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTP 788
Query: 775 TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA 834
+VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+A+ ++W V
Sbjct: 789 VYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSD 848
Query: 835 QVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN 894
V+G LR Y YWRE S K+ + P + ++S L PYS+Y LE+ N
Sbjct: 849 TVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVN 908
Query: 895 GRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 953
GRG GP SE F+TPEGVP P + + ++ L W P NG++ GY L Y
Sbjct: 909 GRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAF 968
Query: 954 DEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1003
+ G+ P + P RYRF L A T+ G GEA+ E
Sbjct: 969 NGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEE 1018
Score = 234 bits (596), Expect = 5e-61
Identities = 299/1200 (24%), Positives = 477/1200 (39%), Gaps = 126/1200 (10%)
Query: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 182 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 237
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 238 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 295
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 296 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 327
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 328 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 382
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 443 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 499
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 500 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 559
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 560 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 619
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 620 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-KLS 675
Q + RV P+ K D E Y ++ S T+ ++
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDD----------EPLYIGNRMKKEDDSLTIFGVA 594
Query: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
++ A + +++ +T P++ P D++ ++ +TW P
Sbjct: 595 ERDQGSYTCVASTELD----QDLAKAYLTVLGRPDR-PRDLELTDLAERSVRLTWIPGDA 649
Query: 736 MDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG 792
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 650 N--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSS 707
Query: 793 PE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWRE 850
P SG P++ P E + + + W P++ G Y V + R
Sbjct: 708 HPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRR 766
Query: 851 GSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFTFS 907
++ + + VV G P Y Y + VQA N G+G P S +S
Sbjct: 767 ETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIGYS 816
Query: 908 TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSFNL 965
+ P + + ++T++ L+W S G L Y Y K
Sbjct: 817 GEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQK 876
Query: 966 RD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1020
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 877 RQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRRFR 935
Query: 1021 TAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQ 1076
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQRTD 994
Query: 1077 PDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAIIL 1127
P + Y L AV + T A AT+GWFIG + AI L
Sbjct: 995 PVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIAL 1054
Query: 1128 LLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLN 1187
L+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +YSD + K SQ SL+
Sbjct: 1055 LVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTSLD 1113
Query: 1188 GDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVAL 1247
G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N +L
Sbjct: 1114 GTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSL 1173
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 732 bits (1889), Expect = 0.0
Identities = 392/1010 (38%), Positives = 556/1010 (55%), Gaps = 31/1010 (3%)
Query: 17 CLL-----IQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHF 71
CLL I+IP +L +PP IT+QS + +V P D+I ++CEA G P F WTR+ F
Sbjct: 17 CLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF 76
Query: 72 KPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P
Sbjct: 77 NIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 132 KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFA 191
WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 192 NVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------SMIDRK 234
NV+ D +DY C+A F T TI QK P L+V + + +R
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 235 PRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQL 294
P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++
Sbjct: 255 PSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRI 314
Query: 295 LKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGR 354
V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G
Sbjct: 315 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGN 374
Query: 355 PQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
P+P V W +NG P++ + + +I + Q S V QC N HG LLANA++
Sbjct: 375 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 434
Query: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYAN 474
V+ +P ++L+ NQ + + L C FG+P+P+++W + L + Y N
Sbjct: 435 SVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
Query: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
G+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+ V C
Sbjct: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLEC 554
Query: 535 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDV 594
+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVASTELD
Sbjct: 555 RVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 595 VESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP 654
++A L V+G P L L+D L + VR++W P + +N+PI Y ++FE+ + P
Sbjct: 612 DLAKAYLTVLGRPDRPRDLELTD---LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQP 668
Query: 655 EKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPV 714
W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A PE NP
Sbjct: 669 GVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPG 728
Query: 715 DVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTS 774
DVKGEG NM ITW P+ P ++Y V+WR + TR W V VV T
Sbjct: 729 DVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTP 788
Query: 775 TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA 834
+VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+A+ ++W V
Sbjct: 789 VYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSD 848
Query: 835 QVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN 894
V+G LR Y YWRE S K+ + P + ++S L PYS+Y LE+ N
Sbjct: 849 TVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVN 908
Query: 895 GRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 953
GRG GP SE F+TPEGVP P + + ++ L W P NG++ GY L Y
Sbjct: 909 GRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAF 968
Query: 954 DEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1003
+ G+ P + P RYRF L A T+ G GEA+ E
Sbjct: 969 NGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEE 1018
Score = 235 bits (599), Expect = 2e-61
Identities = 301/1199 (25%), Positives = 478/1199 (39%), Gaps = 129/1199 (10%)
Query: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 182 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 237
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 238 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 295
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 296 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 327
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 328 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 382
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 443 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 499
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 500 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 559
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 560 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 619
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 620 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-KLS 675
Q + RV P+ K D E Y ++ S T+ ++
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDD----------EPLYIGNRMKKEDDSLTIFGVA 594
Query: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
++ A + +++ +T P++ P D++ ++ +TW P
Sbjct: 595 ERDQGSYTCVASTELD----QDLAKAYLTVLGRPDR-PRDLELTDLAERSVRLTWIPGDA 649
Query: 736 MDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG 792
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 650 N--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSS 707
Query: 793 PE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWRE 850
P SG P++ P E + + + W P++ G Y V + R
Sbjct: 708 HPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRR 766
Query: 851 GSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFTFS 907
++ + + VV G P Y Y + VQA N G+G P S +S
Sbjct: 767 ETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIGYS 816
Query: 908 TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSFNL 965
+ P + + ++T++ L+W S G L Y Y K
Sbjct: 817 GEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQK 876
Query: 966 RD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1020
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 877 RQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRRFR 935
Query: 1021 TAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQ 1076
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQRTD 994
Query: 1077 PDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPP--------AGFATEGWFIGFVSAIILL 1128
P + Y L AV T PP A AT+GWFIG + AI LL
Sbjct: 995 PVSRYRFTLSARTQVGSGEAV----TEESPAPPNEAYTNNQADIATQGWFIGLMCAIALL 1050
Query: 1129 LLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNG 1188
+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +YSD + K SQ SL+G
Sbjct: 1051 VLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTSLDG 1109
Query: 1189 DIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVAL 1247
IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N +L
Sbjct: 1110 TIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSL 1168
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 723 bits (1867), Expect = 0.0
Identities = 393/1022 (38%), Positives = 556/1022 (54%), Gaps = 40/1022 (3%)
Query: 17 CLL-----IQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHF 71
CLL I+IP +L +PP IT+QS + +V P D+I ++CEA G P F WTR+ F
Sbjct: 17 CLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF 76
Query: 72 KPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P
Sbjct: 77 NIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 132 KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFA 191
WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 192 NVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------SMIDRK 234
NV+ D +DY C+A F T TI QK P L+V + + +R
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 235 PRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQL 294
P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++
Sbjct: 255 PSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRI 314
Query: 295 LKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGR 354
V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G
Sbjct: 315 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGN 374
Query: 355 PQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
P+P V W +NG P++ + + +I + Q S V QC N HG LLANA++
Sbjct: 375 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 434
Query: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYAN 474
V+ +P ++L+ NQ + + L C FG+P+P+++W + L + Y N
Sbjct: 435 SVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
Query: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
G+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+ V C
Sbjct: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLEC 554
Query: 535 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDV 594
+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVASTELD
Sbjct: 555 RVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 595 VESRAQLLVVGSPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHNAPIEK 642
++A L V+ P RL DL L L + VR++W P + +N+PI
Sbjct: 612 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITD 671
Query: 643 YDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETV 702
Y ++FE+ + P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE
Sbjct: 672 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 731
Query: 703 VTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI 762
T A PE NP DVKGEG NM ITW P+ P ++Y V+WR + TR W
Sbjct: 732 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 791
Query: 763 VSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSS 822
V VV T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+
Sbjct: 792 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNST 851
Query: 823 AVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP 882
A+ ++W V V+G LR Y YWRE S K+ + P + ++S L P
Sbjct: 852 AISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFP 911
Query: 883 YSSYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNG 941
YS+Y LE+ NGRG GP SE F+TPEGVP P + + ++ L W P NG
Sbjct: 912 YSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNG 971
Query: 942 VLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIV 1001
++ GY L Y + G+ P + P RYRF L A T+ G GEA+
Sbjct: 972 IMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVT 1031
Query: 1002 RE 1003
E
Sbjct: 1032 EE 1033
Score = 241 bits (615), Expect = 3e-63
Identities = 302/1202 (25%), Positives = 477/1202 (39%), Gaps = 115/1202 (9%)
Query: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 182 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 237
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 238 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 295
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 296 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 327
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 328 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 382
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 443 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 499
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 500 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 559
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 560 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 619
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 620 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL---GKVPGNQTSTTLK 673
Q + RV P+ K D ++ SL G +Q S T
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCV 604
Query: 674 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 733
S + + + +P + P+ P++ P D++ ++ +TW P
Sbjct: 605 ASTELDQDLAKAYLTVLAD-QATPTNRLAALPKGRPDR-PRDLELTDLAERSVRLTWIPG 662
Query: 734 RWMDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 790
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 663 DAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
Query: 791 KGPE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 848
P SG P++ P E + + + W P++ G Y V +
Sbjct: 721 SSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
Query: 849 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFT 905
R ++ + + VV G P Y Y + VQA N G+G P S
Sbjct: 780 RRETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIG 829
Query: 906 FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSF 963
+S + P + + ++T++ L+W S G L Y Y K
Sbjct: 830 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 889
Query: 964 NLRD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI 1018
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 890 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRR 948
Query: 1019 SATAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWD 1074
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 949 FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQR 1007
Query: 1075 LQPDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAI 1125
P + Y L AV + T A AT+GWFIG + AI
Sbjct: 1008 TDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAI 1067
Query: 1126 ILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPS 1185
LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +YSD + K SQ S
Sbjct: 1068 ALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTS 1126
Query: 1186 LNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAV 1245
L+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N
Sbjct: 1127 LDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIY 1186
Query: 1246 AL 1247
+L
Sbjct: 1187 SL 1188
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 624 bits (1608), Expect = e-178
Identities = 342/892 (38%), Positives = 485/892 (54%), Gaps = 25/892 (2%)
Query: 22 IPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTV 81
I EL +PP IT+QS + +V P D+I ++CEA G P F WTR+ F ++ V++
Sbjct: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Query: 82 YQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPV 141
+ SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P WPKE + PV
Sbjct: 93 RR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 142 EVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSD 201
V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+NV+ D +D
Sbjct: 151 VVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 210
Query: 202 YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA 261
Y C+A F T TI QK P L+V T + +R P ++P ++S + L+G L+LECIA
Sbjct: 211 YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270
Query: 262 EGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYY 321
G PTP I W + G +P+D+ ++N NK L++ V EED GEY CLA N +GS RH
Sbjct: 271 SGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 322 VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR 381
V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG P++ + +
Sbjct: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 390
Query: 382 GALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYL 441
+I + Q S V QC N HG LLANA++ V+ +P ++L+ NQ + + L
Sbjct: 391 DTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRL 450
Query: 442 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 501
C FG+P+P+++W + L + Y NG+L I+ ++ D G Y C+A N
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 502 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDS 561
L+VKD T+I + P + ++G+ V C+ DPSL+ +++W D L +G+
Sbjct: 511 ENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY-IGNR 569
Query: 562 DKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPG-PVPRLVL----- 615
K ED L I + DQG+Y+CVASTELD ++A L V+ P RL
Sbjct: 570 MKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGR 627
Query: 616 ----SDLHL--LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTS 669
DL L L + VR++W P + +N+PI Y ++FE+ + P W+ K PG+ S
Sbjct: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 687
Query: 670 TTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVIT 729
L+LSPYV+Y FRV AIN+ G PS SE T A PE NP DVKGEG NM IT
Sbjct: 688 AVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEIT 747
Query: 730 WKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQ 789
W P+ P ++Y V+WR + TR W V VV T +VPYEI+VQA N
Sbjct: 748 WTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDF 807
Query: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 849
GKGPEP+ IGYSGED P A P + N + ++W + G + GY + Y
Sbjct: 808 GKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKYVA 864
Query: 850 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPA 901
K K+ + N T + P S Y + A GSG A
Sbjct: 865 FNG-TKVGKQIVEN----FSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 911
Score = 151 bits (382), Expect = 3e-36
Identities = 208/910 (22%), Positives = 346/910 (38%), Gaps = 72/910 (7%)
Query: 131 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 190
P K++ K V+ +++++ C + P + NS+ +I +D RV+M +
Sbjct: 41 PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLV 100
Query: 191 ANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 246
+ + + +Y C A + + +R++ + S L+P +
Sbjct: 101 IDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP-------LWPKENLDP 149
Query: 247 LVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLLKVGEED-DG 303
+V +G PL L+C G P+P I W+ S P+ D+ Q HN L V +D
Sbjct: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 304 EYRCLAENSLGSA---RHAYYVTVEAAPYWLHKPQSHLYGPGETAR----------LDCQ 350
+Y C A ++ + + V + S +Y G + L+C
Sbjct: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
Query: 351 VQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 409
G P P++ W G +L D+ K+ AL ++NV D+ C A N+ G +
Sbjct: 270 ASGVPTPDIAWYKKG---GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIR 326
Query: 410 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 469
+ V P + N + G L+C+A G P P+VQW+ LQ
Sbjct: 327 HTISVRVKAAPYWLDEPKN--LILAPGEDGRLVCRANGNPKPTVQWMVNGEP--LQSAPP 382
Query: 470 FP---YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 526
P A T+ RD Q + Y C +N+ + A + V D PR+ + +
Sbjct: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
Query: 527 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 586
F S P++ W +G+ L + + E+G L I + DQG Y+C
Sbjct: 443 ILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 501
Query: 587 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLH---LLTQSQVRVSWSPAEDHNAPIEKY 643
VA+ L E++ +L V P + R+ + Q + RV P+ K
Sbjct: 502 VATNILGKAENQVRL-EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
Query: 644 DIEFEDKEMAPEKWYSL---GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 700
D ++ SL G +Q S T S + + + +P +
Sbjct: 561 DEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLAD-QATPTNR 619
Query: 701 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRP-QGTRGPWQ 759
P+ P++ P D++ ++ +TW P N+P Y VQ+ Q G W
Sbjct: 620 LAALPKGRPDR-PRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWH 676
Query: 760 E--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPE--PQVTIGYSGEDYPQAIPELEG 815
+ + V S +V Y+ +V A+N G P SG P++ P
Sbjct: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVK 735
Query: 816 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 875
E + + + W P++ G Y V + R ++ + + VV
Sbjct: 736 GEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVV------- 788
Query: 876 ILSGLRP-YSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRW 933
G P Y Y + VQA N G GP E + E +P P + + ++ L W
Sbjct: 789 ---GQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
Query: 934 QPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTK 993
P NG++ GY L Y + G+ P + P RYRF L A T+
Sbjct: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
Query: 994 EGPGEAIVRE 1003
G GEA+ E
Sbjct: 906 VGSGEAVTEE 915
Score = 149 bits (377), Expect = 1e-35
Identities = 77/138 (55%), Positives = 98/138 (71%), Gaps = 1/138 (0%)
Query: 1110 AGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFG 1169
A AT+GWFIG + AI LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F
Sbjct: 1103 ADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF- 1161
Query: 1170 EYSDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAA 1229
+YSD + K SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE
Sbjct: 1162 DYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEET 1221
Query: 1230 GGNDSSGATSPINPAVAL 1247
GN+SS ATSP+N +L
Sbjct: 1222 EGNESSEATSPVNAIYSL 1239
Score = 38.1 bits (87), Expect = 0.053
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 909 PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDP 968
P+G P P L L + S+ L W P ++N +T YV+ + D+ G + + P
Sbjct: 624 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE-DQFQPGVWHDHSKYP 682
Query: 969 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGE---- 1024
+ LSP++ Y+F++ A + G + SG N GE
Sbjct: 683 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL-PSERYRTSGAPPESNPGDVKGEGTRK 741
Query: 1025 NYSVVSWVPKEGQCNF 1040
N ++W P F
Sbjct: 742 NNMEITWTPMNATSAF 757
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 459 bits (1181), Expect = e-129
Identities = 233/595 (39%), Positives = 345/595 (57%), Gaps = 10/595 (1%)
Query: 17 CLL-----IQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHF 71
CLL I+IP +L +PP IT+QS + +V P D+I ++CEA G P F WTR+ F
Sbjct: 17 CLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF 76
Query: 72 KPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P
Sbjct: 77 NIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 132 KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFA 191
WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 192 NVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQ 251
NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S + L+
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLR 254
Query: 252 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAEN 311
G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY CLA N
Sbjct: 255 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 314
Query: 312 SLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEEL 371
+GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG P++
Sbjct: 315 KMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSA 374
Query: 372 AKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTY 431
+ + +I + Q S V QC N HG LLANA++ V+ +P ++L+ NQ
Sbjct: 375 PPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLI 434
Query: 432 MAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYF 491
+ + L C FG+P+P+++W + L + Y NG+L I+ ++ D G Y
Sbjct: 435 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 494
Query: 492 CLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGD 551
C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ +++W D
Sbjct: 495 CVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 554
Query: 552 GRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 606
L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+G+
Sbjct: 555 DEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGN 606
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/295 (24%), Positives = 119/295 (40%), Gaps = 28/295 (9%)
Query: 335 QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR--GALIL---SNV 389
+ H+ P + ++C+ +G P P W N +AKD + ++R G L++ S
Sbjct: 43 KDHIVDPRDNILIECEAKGNPAPSFHWTRNS-RFFNIAKDPRVSMRRRSGTLVIDFRSGG 101
Query: 390 QPSDTMVT-QCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAF- 446
+P + QC ARN+ G L+N V + + +N + VQ G+ L C
Sbjct: 102 RPEEYEGEYQCFARNKFGTALSNRIRLQVS-KSPLWPKENLDPVVVQEGAPLTLQCNPPP 160
Query: 447 GAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAND-------TGRYFCLAANDQN 499
G P P + W+ + QD+R NG L ++ D R+ Q
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 220
Query: 500 N---VTIMANLKVKDATQITQGPRSTIEK----KGSRVTFTCQASFDPSLQPSITWRGDG 552
N + ++ V + T P+ T +G + C AS P+ P I W G
Sbjct: 221 NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT--PDIAWYKKG 278
Query: 553 RDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 607
DL D K+ + L I ++ D G Y C+AS ++ + + V +P
Sbjct: 279 GDLPS--DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 331
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 455 bits (1171), Expect = e-127
Identities = 229/585 (39%), Positives = 339/585 (57%), Gaps = 5/585 (0%)
Query: 22 IPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTV 81
I EL +PP IT+QS + +V P D+I ++CEA G P F WTR+ F ++ V++
Sbjct: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Query: 82 YQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPV 141
+ SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P WPKE + PV
Sbjct: 93 RR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 142 EVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSD 201
V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+NV+ D +D
Sbjct: 151 VVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 210
Query: 202 YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA 261
Y C+A F T TI QK P L+V T + +R P ++P ++S + L+G L+LECIA
Sbjct: 211 YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270
Query: 262 EGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYY 321
G PTP I W + G +P+D+ ++N NK L++ V EED GEY CLA N +GS RH
Sbjct: 271 SGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
Query: 322 VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR 381
V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG P++ + +
Sbjct: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 390
Query: 382 GALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYL 441
+I + Q S V QC N HG LLANA++ V+ +P ++L+ NQ + + L
Sbjct: 391 DTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRL 450
Query: 442 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 501
C FG+P+P+++W + L + Y NG+L I+ ++ D G Y C+A N
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 502 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDS 561
L+VKD T+I + P + ++G+ V C+ DPSL+ +++W D L +G+
Sbjct: 511 ENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY-IGNR 569
Query: 562 DKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 606
K ED L I + DQG+Y+CVASTELD ++A L V+G+
Sbjct: 570 MKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGN 612
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/295 (24%), Positives = 119/295 (40%), Gaps = 28/295 (9%)
Query: 335 QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR--GALIL---SNV 389
+ H+ P + ++C+ +G P P W N +AKD + ++R G L++ S
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNS-RFFNIAKDPRVSMRRRSGTLVIDFRSGG 107
Query: 390 QPSDTMVT-QCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAF- 446
+P + QC ARN+ G L+N V + + +N + VQ G+ L C
Sbjct: 108 RPEEYEGEYQCFARNKFGTALSNRIRLQVS-KSPLWPKENLDPVVVQEGAPLTLQCNPPP 166
Query: 447 GAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAND-------TGRYFCLAANDQN 499
G P P + W+ + QD+R NG L ++ D R+ Q
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 500 N---VTIMANLKVKDATQITQGPRSTIEK----KGSRVTFTCQASFDPSLQPSITWRGDG 552
N + ++ V + T P+ T +G + C AS P+ P I W G
Sbjct: 227 NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT--PDIAWYKKG 284
Query: 553 RDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 607
DL D K+ + L I ++ D G Y C+AS ++ + + V +P
Sbjct: 285 GDLPS--DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 409 bits (1052), Expect = e-114
Identities = 297/1003 (29%), Positives = 463/1003 (46%), Gaps = 68/1003 (6%)
Query: 24 EELMEPPVITEQSPRRLVVFPTDD--ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTV 81
E L++ PV ++ + ++D I+L CEA G P +RW +G ++ +
Sbjct: 20 ELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDI----DMSMEH 75
Query: 82 YQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPV 141
+ G+ + N N+ G Y+CFA+N LGT +S E +L + + V
Sbjct: 76 RYKLNGGNLVVINPNRNWDT---GTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTV 132
Query: 142 EVEEGESVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNH 199
V EG+ VVL C PPP + L W+ N +++D R + Q G+LY + V SD
Sbjct: 133 SVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV- 191
Query: 200 SDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL--LFPTNSSSHLVALQGQPLVL 257
+Y C T + P L +++ M + +P++ FP L A +G + L
Sbjct: 192 GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPET----LPAAKGSTVKL 247
Query: 258 ECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR 317
EC A G P P I W R G + ++ + + L++ +ED G Y C+AENS G
Sbjct: 248 ECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNV 307
Query: 318 HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY 377
+T A P+W+ + ++ +C+ G+P+P W NG L +++
Sbjct: 308 ARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA---LVLEERT 364
Query: 378 RIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-G 436
+I+ GAL +SN+ +D+ + QC A N+HGL+ ++A + VV + + VQ G
Sbjct: 365 QIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVG 424
Query: 437 STAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 496
S L CK +P W D +V + ER +G L I ++ D G Y C+A N
Sbjct: 425 SLVSLDCKPRASPRALSSWKKGD-VSVQEHERISLLNDGGLKIANVTKADAGTYTCMAEN 483
Query: 497 DQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-------- 548
+L V + T+IT P + G V CQ DP L TW
Sbjct: 484 QFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALAD 543
Query: 549 -RGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 607
+ DG +++G S G L+I ++ G Y C+ T +D V S A L+V GSP
Sbjct: 544 FKKDGSHFEKVGGSSS-----GDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSP 598
Query: 608 GPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPG-- 665
GP + + ++ T + ++SW +D+++P+ Y I+ W ++ VP
Sbjct: 599 GPPENVKVDEI---TDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEVI 653
Query: 666 ---NQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 722
T+T ++L+P+V Y FRV A NK G GEPS SE V T EA PE P +V G G
Sbjct: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGS 713
Query: 723 TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFLVVSNTS--TFV 777
+ +VITW P+ N Y V +RP G W + +V+ P V N S +
Sbjct: 714 RSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPYS 772
Query: 778 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 837
PYE+KV N++G+GP VT +S E+ P P L+SS + V W +
Sbjct: 773 PYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSN 832
Query: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
GHL GY V YW G + + S + + V N TS L GL+ +Y+ V+A+N G
Sbjct: 833 GHLLGYEVRYWNGGGKEESSSK------MKVAGNETSARLRGLKSNLAYYTAVRAYNSAG 886
Query: 898 SGP-ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLD 954
+GP ++ +T + P P + ++T +LL W+ + + +TGY + Y
Sbjct: 887 AGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSS 946
Query: 955 EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
+ L+ N EL D Y +++ATT G G
Sbjct: 947 QNNVQVLNTNKTSAELVLPIKED------YIIEVKATTDGGDG 983
Score = 38.9 bits (89), Expect = 0.031
Identities = 42/187 (22%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 911 GVPGHPEALHLECQSNTSLLLRWQPPL-SHNGVLTGYVLSYHPLDEGGKGQLSF-NLRDP 968
G PG PE + ++ ++T+ L W+ +H+ V++ + + P G + + + D
Sbjct: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDG 655
Query: 969 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAG---EN 1025
+ T + +L+P + Y F++ A+ K G GE + + + G +
Sbjct: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
Query: 1026 YSVVSW--VPKEGQC--NFRFHILFKALGEEKGGASL-----SPQYVSYNQSSYTQWDLQ 1076
V++W VP+E Q F + + F+ LG ++ +P+YV N+S +
Sbjct: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNES------IV 769
Query: 1077 PDTDYEI 1083
P + YE+
Sbjct: 770 PYSPYEV 776
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 404 bits (1037), Expect = e-112
Identities = 280/943 (29%), Positives = 451/943 (47%), Gaps = 70/943 (7%)
Query: 41 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNN 96
++FPTD ++L CE G P +RW R+G + + ++ G+F I+ +
Sbjct: 108 IIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLID----GTFIISNPS 163
Query: 97 SNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPP 156
+ G Y+C A+N +G+ +S E L + T V V EG+ VVL C+PP
Sbjct: 164 E---AKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220
Query: 157 PSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTI 214
P + + W+ N + +D R + Q GNLY + V TSD S YIC T
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNAR 279
Query: 215 IQKEPIDLRVKATNSMIDRKPRLL--FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL 272
+ P L ++ M + +P++ FP + A +G + +EC A G P PTI W+
Sbjct: 280 VLSPPTPLTLRNDGVMGEYEPKIEVHFPFT----VTAAKGTTVKMECFALGNPVPTITWM 335
Query: 273 RPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH 332
+ +G +P+ + + L++ V +D G Y C AENS G + V P+W+
Sbjct: 336 KVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394
Query: 333 KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS 392
K G R +C+ G+P+P W NG+P L+ + + G L++ NV S
Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVP---LSPQSRVEMVNGVLMIHNVNQS 451
Query: 393 DTMVTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 451
D + QC A N++G + A+A + ++ P L +T + + + CK G+P P
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Query: 452 SVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 511
++ W D V +++R +G+L I + +D G+Y C N + I+A+L VK+
Sbjct: 512 TISWKKGD-RAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570
Query: 512 ATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG---DSDKYFI 566
T+I P+ T G + C+A D SL + W +G D +E G +S +
Sbjct: 571 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 630
Query: 567 EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQV 626
L+I ++ G Y C T D V A+LLV G PGP +++ ++ T+S
Sbjct: 631 SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEI---TESTA 687
Query: 627 RVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYT 681
+SWSPA D+++PI Y+++ W ++ VP +++ + L+P+V Y
Sbjct: 688 TLSWSPAADNHSPISSYNLQARSPFSLG--WQTVKTVPEIITGDMESAMAVDLNPWVEYE 745
Query: 682 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 741
FRV A N G G+PS S + T EA P+ P +V G +VI W+P+ N
Sbjct: 746 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 805
Query: 742 QVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFV----------PYEIKVQAVNSQGK 791
Y V +RP GTRG W+E++V+ S S F+ P+E+KV N++G
Sbjct: 806 GFGYIVAFRPNGTRG-WKEKMVTS-----SEASKFIYRDESVPPLTPFEVKVGVYNNKGD 859
Query: 792 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREG 851
GP Q+ + S E P A P ++ S +LV W+ + + G +G+ V YW++
Sbjct: 860 GPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDM 917
Query: 852 SQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG-PASEFTFSTPE 910
Q + + V N + VIL+GL + YH V+A+NG G G P+SE + +T +
Sbjct: 918 EQEDTA------ETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKK 971
Query: 911 GVPGH-PEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 950
P P L E Q + + L W+P PL++ + GY + Y
Sbjct: 972 SPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY 1013
Score = 99.0 bits (245), Expect = 3e-20
Identities = 160/698 (22%), Positives = 265/698 (37%), Gaps = 91/698 (13%)
Query: 252 GQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 310
G PL EC A G P PT +WL+ P+ P RV + N L + V + D G Y+CLAE
Sbjct: 404 GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV--EMVNGVLMIHNVNQSDAGMYQCLAE 461
Query: 311 NSLGS--ARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 367
N G+ A + A + L++ ++ + + ++C+ QG P+P ++W+
Sbjct: 462 NKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRA 521
Query: 368 VEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTAD 427
V E + + G+L + N SD C N G A + V + P +I
Sbjct: 522 VRE--NKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE-PTRIELTP 578
Query: 428 NQTYMAVQGSTAYLLCKAF-GAPVPSVQWLDEDGTTVLQDERFFPY-------ANGTLGI 479
+T + V G + L CKA A + + G + +E + ++ L I
Sbjct: 579 KRTELTV-GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 637
Query: 480 RDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTI---EKKGSRVTFTCQA 536
R++ GRY C ++V+ A L V+ GP + E S T +
Sbjct: 638 RNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP----GPPGIVIVEEITESTATLSWSP 693
Query: 537 SFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVE 596
+ D + P ++ R LG + + ++ ++ + + + E VV
Sbjct: 694 AAD-NHSPISSYNLQARSPFSLGWQTVKTVPE--IITGDMESAMAVDLNPWVEYEFRVVA 750
Query: 597 SRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI--EKYDIEFEDKE--- 651
+ + G P R++ ++ + + VS H I E EF++ E
Sbjct: 751 TNP--IGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFG 808
Query: 652 ----MAPE--KWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSET 701
P + + V ++ S + + P + +V N G G P S+
Sbjct: 809 YIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDG---PFSQI 865
Query: 702 VV--TPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR-GPW 758
VV + E P P DVK + +++ WK ++ RPQG G W
Sbjct: 866 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK-----------ESLGRPQGFEVGYW 914
Query: 759 QEQIVSDP-----------FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYP 807
++ D F++++ Y V+A N G GP + + P
Sbjct: 915 KDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPP 974
Query: 808 QAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHI---HKD 864
P E S V + W PV + + GY V Y +EG HS + K
Sbjct: 975 SQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFYRQEG----HSNSQVIETQKL 1029
Query: 865 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS 902
VVP V Y +EV+A++ G G AS
Sbjct: 1030 QAVVPLPDAGV----------YIIEVRAYSEGGDGTAS 1057
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
P Q + ++V ++ ++C+ G P+ W + + + + + G
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-----PDG 534
Query: 89 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 148
S I N ++ +G Y C N G+A I ++ P + T K E+ GES
Sbjct: 535 SLRIL----NASKSDEGKYVCRGENVFGSA--EIIASLSVKEPTRIELTPKRTELTVGES 588
Query: 149 VVLPCNPPPSAE-PLRIYW 166
+VL C A + YW
Sbjct: 589 IVLNCKAIHDASLDVTFYW 607
Score = 33.5 bits (75), Expect = 1.3
Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 19/135 (14%)
Query: 911 GVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH-PLDEGGKGQLSFNLRDPE 969
G PG P + +E + ++ L W P ++ ++ Y L P G + + PE
Sbjct: 669 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTV----PE 724
Query: 970 LRTHNL-----TDLSPHLRYRFQLQATTKEGPGE-----AIVREGGTMALSGISDFGNIS 1019
+ T ++ DL+P + Y F++ AT G G+ ++R + + + N+S
Sbjct: 725 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPT---NVS 781
Query: 1020 ATAGENYS-VVSWVP 1033
+G + V++W P
Sbjct: 782 GRSGRRHELVIAWEP 796
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 404 bits (1037), Expect = e-112
Identities = 280/943 (29%), Positives = 451/943 (47%), Gaps = 70/943 (7%)
Query: 41 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNN 96
++FPTD ++L CE G P +RW R+G + + ++ G+F I+ +
Sbjct: 34 IIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLID----GTFIISNPS 89
Query: 97 SNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPP 156
+ G Y+C A+N +G+ +S E L + T V V EG+ VVL C+PP
Sbjct: 90 E---AKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 146
Query: 157 PSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTI 214
P + + W+ N + +D R + Q GNLY + V TSD S YIC T
Sbjct: 147 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNAR 205
Query: 215 IQKEPIDLRVKATNSMIDRKPRLL--FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL 272
+ P L ++ M + +P++ FP + A +G + +EC A G P PTI W+
Sbjct: 206 VLSPPTPLTLRNDGVMGEYEPKIEVHFPFT----VTAAKGTTVKMECFALGNPVPTITWM 261
Query: 273 RPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH 332
+ +G +P+ + + L++ V +D G Y C AENS G + V P+W+
Sbjct: 262 KVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 320
Query: 333 KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS 392
K G R +C+ G+P+P W NG+P L+ + + G L++ NV S
Sbjct: 321 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVP---LSPQSRVEMVNGVLMIHNVNQS 377
Query: 393 DTMVTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 451
D + QC A N++G + A+A + ++ P L +T + + + CK G+P P
Sbjct: 378 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 437
Query: 452 SVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 511
++ W D V +++R +G+L I + +D G+Y C N + I+A+L VK+
Sbjct: 438 TISWKKGD-RAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 496
Query: 512 ATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG---DSDKYFI 566
T+I P+ T G + C+A D SL + W +G D +E G +S +
Sbjct: 497 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 556
Query: 567 EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQV 626
L+I ++ G Y C T D V A+LLV G PGP +++ ++ T+S
Sbjct: 557 SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEI---TESTA 613
Query: 627 RVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYT 681
+SWSPA D+++PI Y+++ W ++ VP +++ + L+P+V Y
Sbjct: 614 TLSWSPAADNHSPISSYNLQARSPFSLG--WQTVKTVPEIITGDMESAMAVDLNPWVEYE 671
Query: 682 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 741
FRV A N G G+PS S + T EA P+ P +V G +VI W+P+ N
Sbjct: 672 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 731
Query: 742 QVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFV----------PYEIKVQAVNSQGK 791
Y V +RP GTRG W+E++V+ S S F+ P+E+KV N++G
Sbjct: 732 GFGYIVAFRPNGTRG-WKEKMVTS-----SEASKFIYRDESVPPLTPFEVKVGVYNNKGD 785
Query: 792 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREG 851
GP Q+ + S E P A P ++ S +LV W+ + + G +G+ V YW++
Sbjct: 786 GPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDM 843
Query: 852 SQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG-PASEFTFSTPE 910
Q + + V N + VIL+GL + YH V+A+NG G G P+SE + +T +
Sbjct: 844 EQEDTA------ETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKK 897
Query: 911 GVPGH-PEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 950
P P L E Q + + L W+P PL++ + GY + Y
Sbjct: 898 SPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY 939
Score = 99.0 bits (245), Expect = 3e-20
Identities = 160/698 (22%), Positives = 265/698 (37%), Gaps = 91/698 (13%)
Query: 252 GQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 310
G PL EC A G P PT +WL+ P+ P RV + N L + V + D G Y+CLAE
Sbjct: 330 GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV--EMVNGVLMIHNVNQSDAGMYQCLAE 387
Query: 311 NSLGS--ARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 367
N G+ A + A + L++ ++ + + ++C+ QG P+P ++W+
Sbjct: 388 NKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRA 447
Query: 368 VEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTAD 427
V E + + G+L + N SD C N G A + V + P +I
Sbjct: 448 VRE--NKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE-PTRIELTP 504
Query: 428 NQTYMAVQGSTAYLLCKAF-GAPVPSVQWLDEDGTTVLQDERFFPY-------ANGTLGI 479
+T + V G + L CKA A + + G + +E + ++ L I
Sbjct: 505 KRTELTV-GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 563
Query: 480 RDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTI---EKKGSRVTFTCQA 536
R++ GRY C ++V+ A L V+ GP + E S T +
Sbjct: 564 RNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP----GPPGIVIVEEITESTATLSWSP 619
Query: 537 SFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVE 596
+ D + P ++ R LG + + ++ ++ + + + E VV
Sbjct: 620 AAD-NHSPISSYNLQARSPFSLGWQTVKTVPE--IITGDMESAMAVDLNPWVEYEFRVVA 676
Query: 597 SRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI--EKYDIEFEDKE--- 651
+ + G P R++ ++ + + VS H I E EF++ E
Sbjct: 677 TNP--IGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFG 734
Query: 652 ----MAPE--KWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSET 701
P + + V ++ S + + P + +V N G G P S+
Sbjct: 735 YIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDG---PFSQI 791
Query: 702 VV--TPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR-GPW 758
VV + E P P DVK + +++ WK ++ RPQG G W
Sbjct: 792 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK-----------ESLGRPQGFEVGYW 840
Query: 759 QEQIVSDP-----------FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYP 807
++ D F++++ Y V+A N G GP + + P
Sbjct: 841 KDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPP 900
Query: 808 QAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHI---HKD 864
P E S V + W PV + + GY V Y +EG HS + K
Sbjct: 901 SQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFYRQEG----HSNSQVIETQKL 955
Query: 865 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS 902
VVP V Y +EV+A++ G G AS
Sbjct: 956 QAVVPLPDAGV----------YIIEVRAYSEGGDGTAS 983
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
P Q + ++V ++ ++C+ G P+ W + + + + + G
Sbjct: 406 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-----PDG 460
Query: 89 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 148
S I N ++ +G Y C N G+A I ++ P + T K E+ GES
Sbjct: 461 SLRIL----NASKSDEGKYVCRGENVFGSA--EIIASLSVKEPTRIELTPKRTELTVGES 514
Query: 149 VVLPCNPPPSAE-PLRIYW 166
+VL C A + YW
Sbjct: 515 IVLNCKAIHDASLDVTFYW 533
Score = 33.5 bits (75), Expect = 1.3
Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 19/135 (14%)
Query: 911 GVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH-PLDEGGKGQLSFNLRDPE 969
G PG P + +E + ++ L W P ++ ++ Y L P G + + PE
Sbjct: 595 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTV----PE 650
Query: 970 LRTHNL-----TDLSPHLRYRFQLQATTKEGPGE-----AIVREGGTMALSGISDFGNIS 1019
+ T ++ DL+P + Y F++ AT G G+ ++R + + + N+S
Sbjct: 651 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPT---NVS 707
Query: 1020 ATAGENYS-VVSWVP 1033
+G + V++W P
Sbjct: 708 GRSGRRHELVIAWEP 722
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 386 bits (992), Expect = e-107
Identities = 296/945 (31%), Positives = 430/945 (45%), Gaps = 74/945 (7%)
Query: 41 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGN- 95
V+FP + + L C A P +RW +G K + P S + GN
Sbjct: 46 VLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLE----------PGSRHQLVGGNL 95
Query: 96 ---NSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLP 152
N AQ G+Y+C ASN +GT +S E L ++ KE PV+ EG V+LP
Sbjct: 96 VIMNPTKAQD-AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLP 154
Query: 153 CNPPPSAEPLRIYWMNSKILH-IKQDERVTMGQN-GNLYFANVLTSDNHSDYIC----HA 206
CNPP L W+ ++ + I D R + Q GNLY A SD +Y C H
Sbjct: 155 CNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDL-GNYSCLATSHM 213
Query: 207 HFPGTRTIIQK-EPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 265
F T+++ K ++L + T + + FP + AL GQ + LEC A G P
Sbjct: 214 DF-STKSVFSKFAQLNLAAEDTR-LFAPSIKARFPAET----YALVGQQVTLECFAFGNP 267
Query: 266 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 325
P IKW + G + T + TLQ+ V ED+G Y C AENS G + V+
Sbjct: 268 VPRIKWRKVDGSLSPQWTTAE---PTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 326 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALI 385
A P WL G R C G+P+P V W NG P LA + + G L
Sbjct: 325 AQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEP---LASQNRVEVLAGDLR 381
Query: 386 LSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKILTADNQTYMAVQGSTAYLLCK 444
S + D+ + QC A N+HG + A+A + V L P L + A +G + C+
Sbjct: 382 FSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ 441
Query: 445 AFGAPVPSVQWLDEDGTTVL-QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTI 503
AP V W GT +L R +GTL IR++ +D G+Y C A N
Sbjct: 442 PRAAPKAVVLW--SKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANS 499
Query: 504 MANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDK 563
L V+DAT+IT P S G +T C AS DP++ + TW D +
Sbjct: 500 TGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 564 YFIED-----GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 618
Y + G L I + G Y+C+A T +D A +LV G PGP +V+ D
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRD- 618
Query: 619 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN-----QTSTTLK 673
+ + +++SWS D+++PI KY ++ KW + P N +T+ L
Sbjct: 619 --IGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAG--KWKQVRTNPANIEGNAETAQVLG 674
Query: 674 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 733
L+P++ Y FRV A N G GEPS S + T EAAP P + G G +++ W P+
Sbjct: 675 LTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM 734
Query: 734 RWMDWNAPQVQYRVQWRPQGTRGPWQEQIV---SDPFLVVSNTST--FVPYEIKVQAVNS 788
N Y + +R QG+ WQ V + V SN S + P+E+K+++ N
Sbjct: 735 SREYQNGDGFGYLLSFRRQGST-HWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNR 793
Query: 789 QGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 848
+G GPE + YS E+ P+ P + ++SS + V W PV + G L GY + YW
Sbjct: 794 RGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ-QDMNGILLGYEIRYW 852
Query: 849 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFS 907
+ G + + D V TS +SGL P + YH+ V+A+N G+GPAS +
Sbjct: 853 KAGDKEAAA------DRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANAT 906
Query: 908 TPEGVPGHPEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 950
T + P P S++SL ++W P P + +TGY + Y
Sbjct: 907 TMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLY 951
Score = 65.1 bits (157), Expect = 4e-10
Identities = 80/379 (21%), Positives = 142/379 (37%), Gaps = 37/379 (9%)
Query: 30 PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGS 89
P I + P ++L+C A G P + +W + P+ Q P S S
Sbjct: 239 PSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP-SVS 297
Query: 90 FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESV 149
F +G Y C A N G + + R++ + P+W K + E + G ++
Sbjct: 298 F-----------EDEGTYECEAENSKGRD-TVQGRIIVQAQPEWLK-VISDTEADIGSNL 344
Query: 150 VLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFP 209
C P + N + L + V G+L F+ L+ ++ Y C A
Sbjct: 345 RWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA---GDLRFSK-LSLEDSGMYQCVAE-N 399
Query: 210 GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTI 269
TI + ++ A + ++ RL + A +G +++ C P +
Sbjct: 400 KHGTIYASAELAVQALAPDFRLNPVRRL---------IPAARGGEILIPCQPRAAPKAVV 450
Query: 270 KWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 329
W + + + + TL + + D+G+Y C AEN +G A ++V A
Sbjct: 451 LWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK 510
Query: 330 WLHKPQSHLYGPGETARLDCQVQGRPQPEV--TWRINGIPVEELAKDQKYRIQRGALILS 387
P S G+ L C P ++ TW ++ P++ YR +
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYR-------RT 563
Query: 388 NVQPSDTMVTQCEARNRHG 406
NV+ + +T A+ RHG
Sbjct: 564 NVKETIGDLTILNAQLRHG 582
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 384 bits (985), Expect = e-106
Identities = 281/972 (28%), Positives = 452/972 (46%), Gaps = 56/972 (5%)
Query: 5 LRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTD----DISLKCEASGKPEV 60
+R +W L++ P + + L+ P+ T++ V+FP D ++ L C A+G P
Sbjct: 1 MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHD--VIFPLDLSKSEVILNCAANGYPSP 58
Query: 61 QFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMS 120
+RW ++G + ++ + GS I NS + G+Y+C A+N LGT +S
Sbjct: 59 HYRWKQNGTDI----DFTMSYHYRLDGGSLAI---NSPHTDQDIGMYQCLATNLLGTILS 111
Query: 121 HEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW-MNSKILHIKQDER 179
+ +L + +T V V EG+ VVL C PPP L W N L++++D R
Sbjct: 112 RKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNR 171
Query: 180 VTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL- 237
+ Q GNLY A V SD +Y C + +Q P L + M + +P++
Sbjct: 172 RFVSQETGNLYIAKVEPSDV-GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIE 230
Query: 238 -LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLK 296
FP + A + + LEC A G P P I W R G +V Y L++
Sbjct: 231 VRFPET----IQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPN 286
Query: 297 VGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQ 356
+ED+G Y C+A N G + A P W K Q+ + +C+ G+P
Sbjct: 287 FQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPN 346
Query: 357 PEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 416
P TW NG E L +++ +I+ G LI++ + SD+ V QC A N++ ++ ANA + V
Sbjct: 347 PWYTWLKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
Query: 417 VQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT-TVLQDERFFPYAN 474
+ + + VQ G + CK P ++ W + GT T+ Q +R F +
Sbjct: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW--KRGTETLRQSKRIFLLED 461
Query: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
G+L I ++ +D G Y C+A N +L VK+ T IT P G + C
Sbjct: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPC 521
Query: 535 QASFDPSLQPSITW--RGDGRDLQE-LGDSDKYFIED-GRLVIHSLDYSDQGNYSCVAST 590
Q S DPS++ W GD DL++ + ++ E G L+I ++ G Y C T
Sbjct: 522 QVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQT 581
Query: 591 ELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDK 650
L+ + + A ++V G PGP + + D+ T ++SW D+N+PI+ + I + +
Sbjct: 582 TLESLSAVADIIVRGPPGPPEDVQVEDISSTTS---QLSWRAGPDNNSPIQIFTI--QTR 636
Query: 651 EMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTP 705
W ++ VP +T + LSP+V Y FRV A N G GEPS SE + T
Sbjct: 637 TPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTK 696
Query: 706 EAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI--V 763
+ P PV++ G G + +VITW+ + N Y + +RP G+ +E++ V
Sbjct: 697 ASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSV 756
Query: 764 SDPFLVVSNTS--TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 821
V N S P+E+KV N++G+G VTI YSGED PQ P ++ ++
Sbjct: 757 ESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSA 816
Query: 822 SAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLR 881
S + V W + + G + GY V YW + S+ + + V N T+ ++GL+
Sbjct: 817 SEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITGLK 870
Query: 882 PYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLS 938
+ Y V+A+N G+GP+S +T + P P A +N+ L L W+ +
Sbjct: 871 ANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTME 930
Query: 939 HNGVLTGYVLSY 950
+ + GY + Y
Sbjct: 931 NESEVLGYKILY 942
Score = 82.4 bits (202), Expect = 2e-15
Identities = 141/684 (20%), Positives = 265/684 (38%), Gaps = 66/684 (9%)
Query: 255 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 313
L+ EC A G P P WL+ + P +R+ +N + +L V D G Y+C AEN
Sbjct: 335 LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKY 392
Query: 314 GSA-RHAYYVTVEAAPYWLHKP--QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEE 370
+A + +AP + P + G + C+ P+ ++W+ E
Sbjct: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG---TET 449
Query: 371 LAKDQK-YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 429
L + ++ + ++ G+L + N+ SD C A N+ G + V + ++T
Sbjct: 450 LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE--RTVITVPPS 507
Query: 430 TYMAVQGSTAYLLCKAFGAPVPSVQ--WLDEDGTTVLQD-----ERFFPYANGTLGIRDL 482
G + L C+ P V W L+ ER + G L IR++
Sbjct: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
Query: 483 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPR-STIEKKGSRVTFTCQASFDPS 541
Q + +G+Y C +++ +A++ V+ + + I S++++ +
Sbjct: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSP 627
Query: 542 LQP---------SITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 592
+Q S+ W+ + E+ + Y + L + + VA +
Sbjct: 628 IQIFTIQTRTPFSVGWQAVAT-VPEILNGKTY-----NATVVGLSPWVEYEFRVVAGNSI 681
Query: 593 DVVESRAQLLVVGSPGPVPRLVLSDLHLL--TQSQVRVSWS--PAEDHNAPIEKYDIEFE 648
+ E ++ + VP + ++H ++S++ ++W P E N Y I F
Sbjct: 682 GIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF- 740
Query: 649 DKEMAPEKWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSETVVT 704
+ + W S KV ++S + + P + +V N G G S V+ V +
Sbjct: 741 -RPVGSTTW-SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVT-IVYS 797
Query: 705 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 764
E P+ P + + M ++W + W + Y V + ++ +I
Sbjct: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRV 857
Query: 765 DPFLVVSNTSTFVP---YEIKVQAVNSQGKGPE-PQVTIGYSGEDYPQAIPELEGIEILN 820
+ N + Y V+A N+ G GP P V + + + P + P L
Sbjct: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV--TTKKSPPSQPPANIAWKLT 915
Query: 821 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
+S + + W V + + + GY + Y Q + SK HI + N TS L L
Sbjct: 916 NSKLCLNWEHVKTMENESEVLGYKILY----RQNRQSKTHI------LETNNTSAEL--L 963
Query: 881 RPY-SSYHLEVQAFNGRGSGPASE 903
P+ Y +E++ + G G +SE
Sbjct: 964 VPFEEDYLIEIRTVSDGGDGSSSE 987
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 383 bits (983), Expect = e-106
Identities = 286/973 (29%), Positives = 446/973 (45%), Gaps = 60/973 (6%)
Query: 5 LRYVWPLLLCSPCLLIQIPEELMEPPV-ITEQSPRRLVVFPTDD----ISLKCEASGKPE 59
+R W LL+ +L + + P+ I E SP V+FP D + L CE G P+
Sbjct: 1 MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSP---VMFPLDSEEKKVKLNCEVKGNPK 57
Query: 60 VQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAM 119
RW +G + G+ S GS I NN N Q G Y+C A+N GT +
Sbjct: 58 PHIRWKLNGTDV----DTGMDFRYSVVEGSLLI--NNPNKTQD-AGTYQCTATNSFGTIV 110
Query: 120 SHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDER 179
S E +L + T V V G+ +VL C PPP + L W+ ++ + + R
Sbjct: 111 SREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRR 170
Query: 180 VTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-- 237
+ GNLY A V SD +Y C T + P L ++ M + +P++
Sbjct: 171 FVSQETGNLYIAKVEKSDV-GNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEV 229
Query: 238 LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKV 297
FP + +G + LEC A G P PTI W R G A + N L++
Sbjct: 230 QFPET----VPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNF 285
Query: 298 GEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQP 357
+ED G Y C+AENS G +T A P W+ K E +C+ GRP+P
Sbjct: 286 QQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKP 345
Query: 358 EVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV 417
W NG P+ L +D + +I++G L ++ V SD + QC A N+HG++ +NA + V+
Sbjct: 346 TYKWLKNGEPL--LTRD-RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 402
Query: 418 QL-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-QDERFFPYANG 475
+ P T + + G + CK +P P W + G +L ++ER +G
Sbjct: 403 AVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDILKENERITISEDG 460
Query: 476 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 535
L I ++ +D G Y C+A N + NL VKD T++ P S G + CQ
Sbjct: 461 NLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQ 520
Query: 536 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR-----LVIHSLDYSDQGNYSCVAST 590
+ D SL TW +G + D D + G+ L+I ++ G Y C+ T
Sbjct: 521 VTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQT 580
Query: 591 ELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDK 650
+D + + A L+V G PGP + + + +T + ++SW P D+++PI Y I + +
Sbjct: 581 SVDRLSAAADLIVRGPPGPPEAVTIDE---ITDTTAQLSWRPGPDNHSPITMYVI--QAR 635
Query: 651 EMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTP 705
W ++ VP T+T + L+P+V Y FR A N G GEPS SE T
Sbjct: 636 TPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTE 695
Query: 706 EAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD 765
EA PE P +V G G + +VITW+ + N Y V +RP G + W +++
Sbjct: 696 EALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYG-KMIWMLTVLAS 754
Query: 766 ---PFLVVSNTST--FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 820
V N S F P+E+KV N++G+GP T+ YS E+ P P L+
Sbjct: 755 ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLS 814
Query: 821 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
++ + V W L + +G ++GY V YWR + +++++ + N TS ++ L
Sbjct: 815 ATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARK------IRTVGNQTSTKITNL 867
Query: 881 RPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPL 937
+ YHL V+A+N G+GP+S +T + P P + S++ ++L W L
Sbjct: 868 KGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKAL 927
Query: 938 SHNGVLTGYVLSY 950
+ + GY + Y
Sbjct: 928 DNESEVKGYKVLY 940
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 345 bits (884), Expect = 2e-94
Identities = 279/974 (28%), Positives = 425/974 (43%), Gaps = 82/974 (8%)
Query: 11 LLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTR 66
++ + CL + ++ P I E+ P ++P + +SL C A P ++W
Sbjct: 12 IISITTCLAVSEEDKGFGP--IFEEQPIN-TIYPEESLEGKVSLNCRARASPFPVYKWRM 68
Query: 67 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 126
+ ++ +T + G + N Q+ GIY C ASN G S E L
Sbjct: 69 NN------GDVDLTSDRYSMVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLS 120
Query: 127 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ 184
+P E V V+EG+ +VL C+PP + L W+ N + I D+R + Q
Sbjct: 121 FGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQ 180
Query: 185 -NGNLYFANVLTSDNHSDYICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLL 238
NGNLY ANV SD +Y C P T+++ K PI R KP
Sbjct: 181 TNGNLYIANVEASDK-GNYSCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPA 231
Query: 239 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 298
+ AL GQ + LEC A G P P I+W + PMP+ L++ +
Sbjct: 232 DIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQ 290
Query: 299 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPE 358
ED+G Y C AEN G +H + V+A P W+ G C G+P P
Sbjct: 291 LEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPT 350
Query: 359 VTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 418
+ W NG Y +G L L +V + + QC A N +G + ANA + ++
Sbjct: 351 IRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILA 399
Query: 419 L-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGT 476
L P + + +A +G + CK AP P W GT ++ R + +G+
Sbjct: 400 LAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGS 457
Query: 477 LGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQA 536
L I ++ ND G Y C A N++ L + D T+I P + G T C A
Sbjct: 458 LEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAA 517
Query: 537 SFDPSLQPSITWRGDGRDLQELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTE 591
SFDP+L + W +G + ++ Y F+ D G L+I + G Y+C A T
Sbjct: 518 SFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTI 577
Query: 592 LDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKE 651
+D + A L+V G PGP L + D+ + V ++WS D+++PI KY I+ K
Sbjct: 578 VDNSSASADLVVRGPPGPPGGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKT 632
Query: 652 MAPEKWYSLGKVP----GN-QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 706
+ + W P GN + + + L P++ Y FRV A N G GEPS S + T
Sbjct: 633 ILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDG 692
Query: 707 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP 766
AAP P DV G G + ITW PL Y V ++P W++ V++P
Sbjct: 693 AAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNP 751
Query: 767 FL--VVSNTSTFVP---YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 821
V T P +++KV+A N++G GP V + S +D P P G+++L+S
Sbjct: 752 DTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSS 811
Query: 822 SAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLR 881
S + V W V ++ + Y + YW + + + R V V + S L L
Sbjct: 812 SEISVHWEHV----LEKIVESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLL 861
Query: 882 PYSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLS 938
P + Y +EV A N G GP S+ + T + P P + +S + ++ W LS
Sbjct: 862 PDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALS 921
Query: 939 HNGVLTGYVLSYHP 952
+ +TGY + Y P
Sbjct: 922 NESTVTGYKVLYRP 935
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 620 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 675
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 808 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 861
Query: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 862 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 919
Query: 736 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 789
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 920 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 971
Query: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 826
G G QV I + P P L G+ +L + +LV
Sbjct: 972 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1003
Score = 33.5 bits (75), Expect = 1.3
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 864 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 920
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 644 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 703
Query: 921 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 977
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 704 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 762
Query: 978 LSPHLRYRFQLQATTKEGPG 997
+SP ++ +++A +G G
Sbjct: 763 MSPSTAFQVKVKAFNNKGDG 782
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 344 bits (882), Expect = 3e-94
Identities = 276/955 (28%), Positives = 416/955 (43%), Gaps = 81/955 (8%)
Query: 30 PVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 85
P+ EQ ++P + +SL C A P ++W + ++ +T +
Sbjct: 41 PIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPVYKWRMNN------GDVDLTSDRYS 92
Query: 86 HSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEE 145
G + N Q+ GIY C ASN G S E L +P E V V+E
Sbjct: 93 MVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKE 150
Query: 146 GESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ-NGNLYFANVLTSDNHSDY 202
G+ +VL C+PP + L W+ N + I D+R + Q NGNLY ANV SD +Y
Sbjct: 151 GKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDK-GNY 209
Query: 203 ICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 257
C P T+++ K PI R KP + AL GQ + L
Sbjct: 210 SCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPADIVVQFKDVYALMGQNVTL 261
Query: 258 ECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR 317
EC A G P P I+W + PMP+ L++ + ED+G Y C AEN G +
Sbjct: 262 ECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDK 320
Query: 318 HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY 377
H + V+A P W+ G C G+P P + W NG Y
Sbjct: 321 HQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-----------Y 369
Query: 378 RIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKILTADNQTYMAVQG 436
+G L L +V + + QC A N +G + ANA + ++ L P + + +A +G
Sbjct: 370 AYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKG 429
Query: 437 STAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGTLGIRDLQANDTGRYFCLAA 495
+ CK AP P W GT ++ R + +G+L I ++ ND G Y C A
Sbjct: 430 GRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
Query: 496 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDL 555
N++ L + D T+I P + G T C ASFDP+L + W +G +
Sbjct: 488 NNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVI 547
Query: 556 QELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPV 610
++ Y F+ D G L+I + G Y+C A T +D + A L+V G PGP
Sbjct: 548 DFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPP 607
Query: 611 PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP----GN 666
L + D+ + V ++WS D+++PI KY I+ K + + W P GN
Sbjct: 608 GGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKTILSDDWKDAKTDPPIIEGN 662
Query: 667 -QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTN 725
+ + + L P++ Y FRV A N G GEPS S + T AAP P DV G G
Sbjct: 663 MEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRE 722
Query: 726 MVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFL--VVSNTSTFVP---YE 780
+ ITW PL Y V ++P W++ V++P V T P ++
Sbjct: 723 LTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVHKDETMSPSTAFQ 781
Query: 781 IKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHL 840
+KV+A N++G GP V + S +D P P G+++L+SS + V W V ++ +
Sbjct: 782 VKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHV----LEKIV 837
Query: 841 RGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP 900
Y + YW + + + R V V + S L L P + Y +EV A N G GP
Sbjct: 838 ESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGP 891
Query: 901 ASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHP 952
S+ + T + P P + +S + ++ W LS+ +TGY + Y P
Sbjct: 892 PSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 620 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 675
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 819 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 872
Query: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 873 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
Query: 736 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 789
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 931 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 982
Query: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 826
G G QV I + P P L G+ +L + +LV
Sbjct: 983 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1014
Score = 33.5 bits (75), Expect = 1.3
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 864 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 920
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 714
Query: 921 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 977
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 715 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
Query: 978 LSPHLRYRFQLQATTKEGPG 997
+SP ++ +++A +G G
Sbjct: 774 MSPSTAFQVKVKAFNNKGDG 793
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 260 bits (664), Expect = 7e-69
Identities = 251/1010 (24%), Positives = 419/1010 (41%), Gaps = 60/1010 (5%)
Query: 9 WPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDG 68
W LL LL + ++ + P TE ++ + + + L C A G ++F+W RD
Sbjct: 84 WALLALQLHLLRALAQDDVAPYFKTEPGLPQIHL-EGNRLVLTCLAEGSWPLEFKWMRD- 141
Query: 69 VHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAE 128
+ +T Y S + + + G YRC N++G + + +
Sbjct: 142 -------DSELTTYSSEYKYIIP------SLQKLDAGFYRCVVRNRMGALLQRKSEVQVA 188
Query: 129 GAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNS--KILHIKQDERVTMGQNG 186
+ +T + V +G + +L P S ++ W KI+ R+ +
Sbjct: 189 YMGSF-MDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKII---PSNRIAITLEN 244
Query: 187 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEP-IDLRV-KATNSMIDRKPRLLFPTNSS 244
L TSD + Y+ + + P I L + + + P ++ P +
Sbjct: 245 QLVILATTTSDAGAYYVQAVNEKNGEN--KTSPFIHLSIARDVGTPETMAPTIVVPPGNR 302
Query: 245 SHLVALQGQPLVLECIAEGFPTP--TIKWLRPSGPMPADRVTYQNHN--KTLQLLKVGEE 300
S V LECIA P ++ W R R+T H+ + L +
Sbjct: 303 S--VVAGSSETTLECIASARPVEDLSVTWKRNGV-----RITSGLHSFGRRLTISNPTSA 355
Query: 301 DDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGP-GETARLDCQVQGRPQ 356
D G Y C L ++ AR ++ + PY+ +P+S + ET + CQ G P
Sbjct: 356 DTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPL 415
Query: 357 PEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 416
P + W + I + L + + G L + ++P D+ + QC A N G + + Y+ V
Sbjct: 416 PTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDV 475
Query: 417 VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDED---GTTVLQDERFFPYA 473
+ A + T G TA L C+ GAP P++ W E+ + ++ RF
Sbjct: 476 TNI-APVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLE 534
Query: 474 NGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFT 533
+G L I + D G Y C AAN + ++ A L V + T I P + KG+ T
Sbjct: 535 SGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLH 594
Query: 534 CQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 593
C A+ DP + W+ D L S +DG L+I D G+YSC +E
Sbjct: 595 CGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGG 654
Query: 594 VVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMA 653
A+L V+ P L++S + + V +SW D N+PI Y +E + +
Sbjct: 655 NDSRMARLEVIELPHSPQNLLVSPNSSHSHAVV-LSWVRPFDGNSPILYYIVELSENN-S 712
Query: 654 PEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKN 712
P K + L V T T+ L+P Y FRV A+N+ G G+ S + ++ PE P
Sbjct: 713 PWKVH-LSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAP 771
Query: 713 PVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP---FLV 769
P ++ G ++++ W+P + N Y +++R G G +Q++ ++ P + +
Sbjct: 772 PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCL 831
Query: 770 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 829
V++ + YEI+V A N G G + Y+ + P A P+ E +NS+ + W
Sbjct: 832 VTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWN 891
Query: 830 PVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD-HVVVPANTTSVILSGLRPYSSYHL 888
P + G +GY + W + + I D H V + T+ L+ +++Y
Sbjct: 892 PPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITN-----LKKFTAYFT 946
Query: 889 EVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYV 947
V F G GP S T E PG L +TSL + WQ PL NG++TGY
Sbjct: 947 SVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQ 1006
Query: 948 LSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
+S+ +L+ L + + + LS Y + A T G G
Sbjct: 1007 ISWEVYGR-NDSRLTHTL-NSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG 1054
Score = 154 bits (389), Expect = 5e-37
Identities = 113/405 (27%), Positives = 185/405 (45%), Gaps = 21/405 (5%)
Query: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEK-WYSLGKVPG 665
PG LV+S++ + + + P D I ++ +E + + E+ W +L +
Sbjct: 1070 PGAPSNLVISNI---SPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEEN 1126
Query: 666 NQTSTTLK---LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 722
+ L+ L+PY HY FR+ +N GP SP S + T +A P+ P V
Sbjct: 1127 EPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTAS 1186
Query: 723 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 777
T++ + W PL +N V YR+++ + Q+VSD + ++
Sbjct: 1187 ETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWM 1246
Query: 778 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 837
YE+++QA N+ G GP +V G + E P A PE E ++S+ +L+ W V
Sbjct: 1247 EYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQN 1306
Query: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
G + GY + + R + H+V +T S +L+GLR + Y L+V AF G
Sbjct: 1307 GLILGYKILF------RAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIG 1360
Query: 898 SG-PASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
+G P++ T + PG P L TS+ + WQPP NG++ GY ++Y L
Sbjct: 1361 NGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYR-LAS 1419
Query: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAI 1000
+ +R TDL+P Y F+L A T++G GE +
Sbjct: 1420 SSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPL 1464
Score = 146 bits (368), Expect = 1e-34
Identities = 223/1033 (21%), Positives = 392/1033 (37%), Gaps = 112/1033 (10%)
Query: 58 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRF--QGIYRCFASNKL 115
P Q W R+G P + +T+ I ++ A + Q + NK
Sbjct: 219 PRPQVTWFREGHKIIPSNRIAITL-----ENQLVILATTTSDAGAYYVQAVNEKNGENKT 273
Query: 116 GTAMSHEIRLMAEGAPKWPKETV------KPVEVEEGESVVLPCNPPPSAEPLRIYWMNS 169
+ I G P+ T+ + V E+ + E L + W +
Sbjct: 274 SPFIHLSIARDV-GTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRN 332
Query: 170 KILHIKQDERVTMGQNG---NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA 226
+ R+T G + L +N ++D Y+C A PG+ EP +A
Sbjct: 333 GV-------RITSGLHSFGRRLTISNPTSADT-GPYVCEAALPGSAF----EP----ARA 376
Query: 227 TNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ 286
T + +P F S + A + + + C A G P PT++W + + + R+
Sbjct: 377 TAFLFIIEPPY-FTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDA--ISISRLQNP 433
Query: 287 NHNKT----LQLLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGP 341
+ L++ K+ ED G ++C A N G + H Y AP + +P
Sbjct: 434 RYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTD 493
Query: 342 GETARLDCQVQGRPQPEVTW-RINGIPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQC 399
G TA L C+V G P+P +TW R N I + ++ + + G L ++ V D C
Sbjct: 494 GMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTC 553
Query: 400 EARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL--- 456
A N G L A+A + V + + ++ ++ ++G+TA L C A P S++++
Sbjct: 554 YAANTEGSLNASATLTVWNRTSIVHPPED--HVVIKGTTATLHCGATHDPRVSLRYVWKK 611
Query: 457 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 516
D T R +G+L I + D G Y C ++ N + MA L+V ++
Sbjct: 612 DNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEV---IELP 668
Query: 517 QGPRSTIEKKGSR----VTFTCQASFD---PSL-------QPSITWR----GDGRDLQEL 558
P++ + S V + FD P L + + W+ G ++ +
Sbjct: 669 HSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGV 728
Query: 559 GDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 618
S + + +++ +G YS E+ +L P P+ +++
Sbjct: 729 TVSGLTPARTYQFRVCAVNEVGRGQYSA---------ETSRLMLPEEPPSAPPKNIVASG 779
Query: 619 HLLTQSQVRVSWSPAED--HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP 676
T + V W P + HN + Y + + + E P L
Sbjct: 780 R--TNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLII 837
Query: 677 YVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWM 736
+ Y +V A N G G S + T T + P P +V+ E +T + W P
Sbjct: 838 WTQYEIQVAAYNGAGLGVFSR-AVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQ 896
Query: 737 DWNAPQVQYRV-QWRPQGTRGPWQEQIVSDPFLV----VSNTSTFVPYEIKVQAVNSQGK 791
N Y++ W I D V ++N F Y V + G
Sbjct: 897 FINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGD 956
Query: 792 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVT---YW 848
GP + ++ ED P A+ L EIL++S + V W+ + + G + GY ++ Y
Sbjct: 957 GPPSTPQLVWTQEDKPGAVGHLSFTEILDTS-LKVSWQ--EPLEKNGIITGYQISWEVYG 1013
Query: 849 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST 908
R S+ H+ + + T + GL ++Y ++V A G+G + T S+
Sbjct: 1014 RNDSRLTHT----------LNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISS 1063
Query: 909 --PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQ---LSF 963
P +PG P L + S S L+++P ++ +++ G + + L
Sbjct: 1064 GVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYE 1123
Query: 964 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA--- 1020
+P+ + + +L+P+ YRF+++ GP L D S
Sbjct: 1124 EENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVR 1183
Query: 1021 TAGENYSVVSWVP 1033
TA E + WVP
Sbjct: 1184 TASETSLRLRWVP 1196
Score = 132 bits (332), Expect = 2e-30
Identities = 133/576 (23%), Positives = 237/576 (41%), Gaps = 50/576 (8%)
Query: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 666
P P PR +L +T +R+ W P D +PI + ++ +E+ +W + +
Sbjct: 1477 PAP-PRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQV--RELPRGEWQTYSSSISH 1533
Query: 667 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 724
+ + + +L P+ Y R+ A N G + S +E V T + P + P V + T+
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 725 NMVITWKPLRWMDWNAPQVQYRVQWRP------QGTRGPW--------QEQIVSDPFLVV 770
+++I W+P R N YR+ +R GT E F V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 771 SNTST-----------FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEIL 819
+++ST + YE+ + A N G+ P + GE P P+ + L
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 820 NSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSG 879
+S + V W P G+++GY + YW SQ + K + + +P V L
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKV----LFLPEPV--VRLKN 1767
Query: 880 LRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLS 938
L ++ Y + + AFN G GP S+ T + PG P L ++T+L + W P +
Sbjct: 1768 LTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 939 HNGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQA-TTKEG 995
NG+L GY + Y PL +G ++ +R R + DL+ + Y F++QA T G
Sbjct: 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYG 1887
Query: 996 PG-EAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKG 1054
P +A + G G ++ T + + W + +A ++G
Sbjct: 1888 PELQANITAGPAEGSPGSP--RDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEG 1945
Query: 1055 GASLSPQYVSYNQSSYTQW--DLQPDTDYEIHL--FKERMFRHQMAVKTNGTGRVRLPPA 1110
+ + + + +SYT L+ YE + E + T + +V P
Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP-- 2003
Query: 1111 GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKY 1146
F E WF+ ++ L++++L++ + + KY
Sbjct: 2004 -FYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKY 2038
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 259 bits (661), Expect = 1e-68
Identities = 183/623 (29%), Positives = 298/623 (47%), Gaps = 38/623 (6%)
Query: 348 DCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGL 407
+C+ GRP+P W NG P+ L +D + +I++G L ++ V SD + QC A N+HG+
Sbjct: 8 ECKANGRPKPTYKWLKNGEPL--LTRD-RIQIEQGTLNITIVNLSDAGMYQCLAENKHGV 64
Query: 408 LLANAYIYVVQL-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQD 466
+ +NA + V+ + P T + + G + CK +P P W + G +L++
Sbjct: 65 IFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDILKE 122
Query: 467 -ERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 525
ER +G L I ++ +D G Y C+A N + NL VKD T++ P S
Sbjct: 123 NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 526 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR-----LVIHSLDYSD 580
G + CQ + D SL TW +G + D D + G+ L+I ++
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKH 242
Query: 581 QGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI 640
G Y C+ T +D + + A L+V G PGP + + ++ T + ++SW P D+++PI
Sbjct: 243 AGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEI---TDTTAQLSWRPGPDNHSPI 299
Query: 641 EKYDIEFEDKEMAPEKWYSLGKVPG-----NQTSTTLKLSPYVHYTFRVTAINKYGPGEP 695
Y I+ W ++ VP T+T + L+P+V Y FR A N G GEP
Sbjct: 300 TMYVIQARTPFSVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEP 357
Query: 696 SPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR 755
S SE T EA PE P +V G G + +VITW+ + N Y V +RP G +
Sbjct: 358 SRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYG-K 416
Query: 756 GPWQEQIVSD---PFLVVSNTST--FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAI 810
W +++ V N S F P+E+KV N++G+GP T+ YS E+ P
Sbjct: 417 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 476
Query: 811 PELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPA 870
P L+++ + V W L + +G ++GY V YWR + +++++ +
Sbjct: 477 PASIFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARK------IRTVG 529
Query: 871 NTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSL 929
N TS ++ L+ YHL V+A+N G+GP+S +T + P P + S++ +
Sbjct: 530 NQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKI 589
Query: 930 LLRWQ--PPLSHNGVLTGYVLSY 950
+L W L + + GY + Y
Sbjct: 590 ILNWDQVKALDNESEVKGYKVLY 612
Score = 77.4 bits (189), Expect = 8e-14
Identities = 86/335 (25%), Positives = 148/335 (44%), Gaps = 65/335 (19%)
Query: 46 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 105
+++ +C+A+G+P+ ++W ++G ++ + + G+ IT N + A G
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQI------EQGTLNITIVNLSDA----G 52
Query: 106 IYRCFASNKLGTAMSH-EIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPSAEPLR 163
+Y+C A NK G S+ E+ ++A G P + + +K V V+ G VV+ C P S +P+
Sbjct: 53 MYQCLAENKHGVIFSNAELSVIAVG-PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVY 111
Query: 164 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA--HFPGTRTIIQKEPID 221
+ IL K++ER+T+ ++GNL NV SD S Y C A HF GT
Sbjct: 112 TWKKGRDIL--KENERITISEDGNLRIINVTKSDAGS-YTCIATNHF-GT---------- 157
Query: 222 LRVKATNSMIDRKP-RLLFPTNSSSHLVALQGQPLVLEC-----------IAEGFPTPTI 269
+T +++ + P R++ P +S V G+ +VL C F I
Sbjct: 158 --ASSTGNLVVKDPTRVMVPPSSMDVTV---GESIVLPCQVTHDHSLDIVFTWSFNGHLI 212
Query: 270 KWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 329
+ R +RV Q+ L + + + G+Y C+ + S+ A + V P
Sbjct: 213 DFDRDGDHF--ERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP- 269
Query: 330 WLHKPQSHLYGPGETARLD------CQVQGRPQPE 358
GP E +D Q+ RP P+
Sbjct: 270 ----------GPPEAVTIDEITDTTAQLSWRPGPD 294
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
Query: 252 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAEN 311
G +V+EC + P P W + + + + + L+++ V + D G Y C+A N
Sbjct: 94 GGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATN 153
Query: 312 SLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEV--TWRING 365
G+A + V+ + P S GE+ L CQV ++ TW NG
Sbjct: 154 HFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNG 209
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 248 bits (633), Expect = 3e-65
Identities = 255/1019 (25%), Positives = 419/1019 (41%), Gaps = 69/1019 (6%)
Query: 8 VWPLLLCSPCLLIQIPEELMEP---PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 64
+W LL+ + L QI + P + R V + + L C A G ++F+W
Sbjct: 1 MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW 60
Query: 65 ---TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSH 121
R+ F + +T H+G YRC N++G +
Sbjct: 61 LHNNRELTKFSLEYRYMITSLDRTHAG-----------------FYRCIVRNRMGALLQR 103
Query: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
+ + + +E K V GE+ V+ S ++ W I R+
Sbjct: 104 QTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG-RKIPPSSRIA 161
Query: 182 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR-KPRLLFP 240
+ L + + D Y+ A +PI L V+ D P ++ P
Sbjct: 162 ITLENTLVILSTVAPDAGRYYV-QAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIP 220
Query: 241 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWL-RPSGPMPADRVTYQNHNKTLQLLKVGE 299
++S V + LEC+A P + + + G + + ++ +HN+ L +
Sbjct: 221 PKNTS--VVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS--DHNRRLTIPNPTG 276
Query: 300 EDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE-TARLDCQVQGRP 355
D G Y C L +S+ S Y++V P ++ +P+ H+ E + CQ +G P
Sbjct: 277 SDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVP 336
Query: 356 QPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
P +TW V E+ K ++R + G L +S + P DT + QC ARN G + + Y+
Sbjct: 337 PPSITW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYL 395
Query: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-----QDERF 469
V + I T + G + L C+ GAP P++ W + G +L Q RF
Sbjct: 396 AVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITW--QKGERILASGSVQLPRF 452
Query: 470 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 529
P +G+L I +D G Y CLA N + A+L V T+IT+ P+ KG++
Sbjct: 453 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 512
Query: 530 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC-VA 588
+ C + DP + W DG L +G L I D G Y+C V
Sbjct: 513 ASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVI 572
Query: 589 STELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFE 648
S + +SR+ L V P ++ L + + + ++W+ D N+P+ +Y +E
Sbjct: 573 SAGGN--DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMS 630
Query: 649 DKEMAPEKW-YSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 706
+ AP W L V TS T+K L P Y FR+ A+N G G+ S +E V PE
Sbjct: 631 ENN-AP--WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPE 687
Query: 707 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP 766
P P +V G +++I W+P N Y +++ G +Q + ++D
Sbjct: 688 EPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDA 747
Query: 767 ---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSA 823
L++ + + YEI+V A NS G G ++ + P P E NS+
Sbjct: 748 DVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTT 807
Query: 824 VLVKWRPVDLAQVKGHLRGYNVTYW---REGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
+ W + G +GY + W +E + R +D + V +SGL
Sbjct: 808 IRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG------FVSGL 861
Query: 881 RPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 939
+ ++ Y V F G GP S T E VPG L +TSL + WQ P
Sbjct: 862 KKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEK 921
Query: 940 NGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGE 998
NG+LTGY +S+ + +++ L + L + +T L+ Y ++ A T +G G+
Sbjct: 922 NGILTGYRISWEEYNRTNT-RVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSKGQGQ 978
Score = 149 bits (377), Expect = 1e-35
Identities = 154/598 (25%), Positives = 257/598 (42%), Gaps = 67/598 (11%)
Query: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 666
P P R ++ + +S V +SW P D +P+ Y I+ +E+ +W +
Sbjct: 1400 PQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYTIQ--TRELPSGRWALHSASVSH 1456
Query: 667 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 724
S+ + +L P+ Y FRV A N G E S SE++ T +AAP++ P + + TT
Sbjct: 1457 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1516
Query: 725 NMVITWKPLRWMDWNAPQVQYRVQWRP---QGTRG-----------PWQE-------QIV 763
+++I W+P N + +R+++R +G RG W E + +
Sbjct: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576
Query: 764 SDPFLV---VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 820
S P L + N + YEI++ N+ G+GP + GE P A P +
Sbjct: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636
Query: 821 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 880
++ + V W P L G ++GY + +W +QR + + + SV L L
Sbjct: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWE--AQRGNLTERVKTLFLA----ENSVKLKNL 1690
Query: 881 RPYSSYHLEVQAFNGRGSGPASEFT-FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 939
Y++Y + V AFN G GP S T T + P P ++ + TS+ + W+ P
Sbjct: 1691 TGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Query: 940 NGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATT-KEGP 996
NG+L GY L Y P +G ++ +++ + DL+ + YRF+++A T GP
Sbjct: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
Query: 997 G-EAIVREG---GTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEE 1052
EA V G G G+ S+ ++S S P +G + +A +
Sbjct: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS--SGDPGKGPIT---RYVIEARPSD 1865
Query: 1053 KGGASLSPQYVSYNQSSYT-QWD-LQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLP-- 1108
+G + + + SSYT D L+P Y+ + +AV G G P
Sbjct: 1866 EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV---------IAVNDYGFGTPSSPSQ 1916
Query: 1109 --PA----GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEA 1160
PA F E WF+ ++ + L+ ++LL+ I R + KY+ K S A
Sbjct: 1917 SVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGA 1974
Score = 146 bits (369), Expect = 1e-34
Identities = 250/1093 (22%), Positives = 416/1093 (38%), Gaps = 123/1093 (11%)
Query: 58 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLG- 116
P+ Q W RDG P + +T+ + I + A R+ Y ++K G
Sbjct: 141 PQPQVTWFRDGRKIPPSSRIAITL-----ENTLVILSTVAPDAGRY---YVQAVNDKNGD 192
Query: 117 TAMSHEIRLMAE--GAPKWPKETV-----KPVEVEEGES-VVLPC--NPPPSAEPLRIYW 166
S I L E G P P K V G S V L C N P + L I W
Sbjct: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK-LHIIW 251
Query: 167 MNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA 226
+L N L N SD Y C A +++ + V+
Sbjct: 252 KKDGVLL----SGGISDHNRRLTIPNPTGSDA-GYYECEA-------VLRSSSVPSVVRG 299
Query: 227 TNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY- 285
+ P+ F H+ A + + + C A+G P P+I W + + + +++T
Sbjct: 300 AYLSVLEPPQ--FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
Query: 286 -QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA-APYWLHKPQSHLYGPGE 343
Q ++ LQ+ + +D G ++C A N+ G + + Y+ V + AP P G
Sbjct: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGM 417
Query: 344 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYR---IQRGALILSNVQPSDTMVTQCE 400
+ L C+ G P+P +TW+ G + Q R ++ G+L++S SD C
Sbjct: 418 SVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
Query: 401 ARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DED 459
A N G+ A+A + VV +I T Q ++G+ A ++C P +++++ ++D
Sbjct: 477 ATNSRGVDEASADL-VVWARTRI-TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKD 534
Query: 460 GTTVLQDE--RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 517
G T+ + R NG+L I + D G Y C + N + A+L+V+ +
Sbjct: 535 GATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
Query: 518 GP---RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFIEDG 569
P ST+E++ +T+T + L I + L + G
Sbjct: 595 HPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKG 654
Query: 570 RLVIHSLDY-----SDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQS 624
+ S + +D G TE R L P ++ S T
Sbjct: 655 LVPARSYQFRLCAVNDVGKGQFSKDTE------RVSLPEEPPTAPPQNVIASGR---TNQ 705
Query: 625 QVRVSWSPA-EDH-NAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL--KLSPYVHY 680
+ + W P E H N ++ Y I + + Y + + L L + +Y
Sbjct: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVG--YQFKNITDADVNNLLLEDLIIWTNY 763
Query: 681 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 740
V A N G G S T T + P P +V E +T + TW NA
Sbjct: 764 EIEVAAYNSAGLGVYSS-KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTW--------NA 814
Query: 741 PQVQY---------RVQWRPQG-------TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQ 784
P Q+ + W P+ T P + + F VS F Y V
Sbjct: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF--VSGLKKFTEYFTSVL 872
Query: 785 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 844
+ G GP + + ED P + L EIL++S + V W+ + + G L GY
Sbjct: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS-LKVSWQ--EPGEKNGILTGYR 929
Query: 845 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEF 904
++ W E ++ H +P T ++GL ++Y +EV A +G G S
Sbjct: 930 IS-WEEYNRTNTRVTHY------LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Query: 905 TFST--PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH--PLDEGGKGQ 960
T S+ P +PG P L + S+ L+++P ++ +++ + EG +
Sbjct: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
Query: 961 LSFNL-RDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF--GN 1017
L L +P+ R+ + DL+P Y F+++ G L D N
Sbjct: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPAN 1102
Query: 1018 IS-ATAGENYSVVSWVP-KEGQCNFRFHIL---FKALGEEKGGASLSPQYVSYNQSSYTQ 1072
+S TA E + W+P E + N + K + G +LS + YT
Sbjct: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
Query: 1073 WDLQPDTDYEIHL 1085
DL+ T+Y + +
Sbjct: 1163 EDLEEWTEYRVQV 1175
Score = 145 bits (367), Expect = 2e-34
Identities = 127/495 (25%), Positives = 213/495 (43%), Gaps = 27/495 (5%)
Query: 607 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP-EKW---YSLGK 662
PGP L +S++ V + + P D I ++ +E + + E+W + L
Sbjct: 993 PGPPTNLGISNIG---PRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
Query: 663 VPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 722
P ++ L+P+ Y+FR+ +N G PS S + T +A P+ P +V
Sbjct: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
Query: 723 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 777
T++ + W PL M++N V Y++++ G +V D + + +
Sbjct: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
Query: 778 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 837
Y ++VQA N+ G GP Q +G + E P + P SS++LV+W V A
Sbjct: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRN 1229
Query: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
G + GY V Y + S + + +V ++ S L+GL Y Y ++V AF G
Sbjct: 1230 GLVLGYKVMYKEKDSDTQ------PRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
Query: 898 SGPASE--FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
G S T + VPG P + TS+ L WQPP + NG++ Y ++ H L+
Sbjct: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNT 1342
Query: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1015
+ + P R + T L P Y F++ A T++G GEA T
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
Query: 1016 GNISATAGENYS----VVSWVP-KEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSY 1070
+ E+ ++SW P +G R++ + + G +L VS+N SS+
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTI-QTRELPSGRWALHSASVSHNASSF 1461
Query: 1071 TQWDLQPDTDYEIHL 1085
L+P T Y+ +
Sbjct: 1462 IVDRLKPFTSYKFRV 1476
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 243 bits (619), Expect = 1e-63
Identities = 250/1012 (24%), Positives = 428/1012 (42%), Gaps = 88/1012 (8%)
Query: 27 MEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPH 86
++ P+ SPR++ +SL C +G + + W R+G P + + +T H
Sbjct: 310 VKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGIN--H 367
Query: 87 SGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEG 146
+ + G Y+CF +A + ++ +G PK + V V
Sbjct: 368 ENLIM-----DHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV-VSPA 421
Query: 147 ESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT--MGQNGNLYFANVLTSDNHSD--- 201
E V L CN + P + ++ + R++ + GN+ ++S D
Sbjct: 422 EPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGV 481
Query: 202 YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA 261
Y C A+ ++ + I++R A+ ++ A+ G+ + C
Sbjct: 482 YRCTAN-NSAGVVLYQARINVRGPAS-------------IRPMKNITAIAGRDTYIHCRV 527
Query: 262 EGFPTPTIKWLRPSGPMPAD--RVTYQNHNKTLQLLKVGEE-DDGEYRC--LAENSLGSA 316
G+P +IKW + S +P + +V ++N N TL+L V +E D+GEY C L + L ++
Sbjct: 528 IGYPYYSIKWYKNSNLLPFNHRQVAFEN-NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTS 586
Query: 317 RHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQP-EVTWRINGIPVEELAKDQ 375
+ + +VTV+ P+ + + + G+ + C V P +TW+ +G P+
Sbjct: 587 Q-SVHVTVKVPPF-IQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVT 644
Query: 376 KYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAV 434
I +L +SN+ C ARN + + + +V++P K + +
Sbjct: 645 IDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD-GI 702
Query: 435 QGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDE------RFFPYANGTLGIRDLQANDTG 488
G L C A G PVP++ W G V Q + R +NG+L I+ + D+G
Sbjct: 703 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 762
Query: 489 RYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSIT 547
Y C +ND +V+ L VK IT P +T+ +G + +C A + + +
Sbjct: 763 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPI--IVR 820
Query: 548 WRGDGRDLQELGDSDKYFI---EDGRLVIHSLDY-----SDQGNYSCVASTELDVVESRA 599
W + R + + +Y + E G VI +L D G +SC A
Sbjct: 821 WEKEDRIINP--EMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGII 878
Query: 600 QLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYS 659
QL V P P P + + D+ T + + W+ D N+PI YDIE ++K + W S
Sbjct: 879 QLTVQEPPDP-PEIEIKDVKART---ITLRWTMGFDGNSPITGYDIECKNKS---DSWDS 931
Query: 660 LGKV----PGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 715
+ P ++T + + P Y+ R+ A N+ G EPS T+ EAAP+ P +
Sbjct: 932 AQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSN-ELTITADEAAPDGPPQE 990
Query: 716 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS------DPFLV 769
V E + ++ +TWK + N Y++ +R T G +Q I+S
Sbjct: 991 VHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYT 1050
Query: 770 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 829
+ N + F Y + VQA N G GP Q I + ED P PE + ++ + W
Sbjct: 1051 LDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWS 1110
Query: 830 PVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLE 889
+ + G L+G+ V YW + + + S+ L GL Y++Y ++
Sbjct: 1111 TLSKEALNGILQGFRVIYWANLMDGELG------EIKNITTTQPSLELDGLEKYTNYSIQ 1164
Query: 890 VQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGY-V 947
V AF G G SE F+ T E VPG P + S + + + W PPL NG++ Y V
Sbjct: 1165 VLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTV 1224
Query: 948 LSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 999
HP +S P+ ++ + +LS + +Y + A T G G +
Sbjct: 1225 FCSHPYPT----VISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNS 1272
Score = 174 bits (442), Expect = 4e-43
Identities = 255/1039 (24%), Positives = 418/1039 (40%), Gaps = 122/1039 (11%)
Query: 48 ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSF--TITG-NNSNFAQRFQ 104
+ L C+A G PE +RW +D + + SG F T+TG N
Sbjct: 242 VELPCKALGHPEPDYRWLKDNMPLE-------------LSGRFQKTVTGLLIENIRPSDS 288
Query: 105 GIYRCFASNKLGTAMSHEIRLMAEGAPKWP-KETVKPVEVEE--GESVVLPCNPPPSAEP 161
G Y C SN+ GTA +++ K P K T+ P +V+ G V L C+ + +
Sbjct: 289 GSYVCEVSNRYGTA-----KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQ 343
Query: 162 LRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPID 221
++ N +IL+ ++ R+T + NL +++ SD + Y C ++K+ +
Sbjct: 344 ELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGA-YQC---------FVRKDKLS 393
Query: 222 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM--- 278
+ + D P+++ ++ S V +P+ L C +G P PTI W P+
Sbjct: 394 AQDYVQVVLEDGTPKII---SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKG 450
Query: 279 PADRVTYQ--NHNKTLQLLKVGE---EDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHK 333
+ R++ + + L + D G YRC A NS G + + V P +
Sbjct: 451 GSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPASIRP 509
Query: 334 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS- 392
++ G + C+V G P + W N + + + G L LS+VQ
Sbjct: 510 MKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLSDVQKEV 568
Query: 393 DTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS 452
D C + L + + V++P I + + G ++ C +P
Sbjct: 569 DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSI--GQRVFIPCVVVSGDLPI 626
Query: 453 VQWLDEDGTT------VLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMAN 506
+DG V D F +L I +L G Y C+A N+ V +
Sbjct: 627 TITWQKDGRPIPGSLGVTIDNIDF---TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 683
Query: 507 LKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW---RGDG-RDLQELGDSD 562
L V+ + PR G V C A P P+I W +G G Q + +
Sbjct: 684 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYP--VPTIVWKFSKGAGVPQFQPIALNG 741
Query: 563 K-YFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLS--DLH 619
+ + +G L+I + D G Y C S ++ S++ L V +P ++ S +
Sbjct: 742 RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV----KIPAMITSYPNTT 797
Query: 620 LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE--KWYSLGKVPGNQTSTTLKLSPY 677
L TQ Q + A I ++ E ED+ + PE ++ K G + +TL++ P
Sbjct: 798 LATQGQKKEMSCTAHGEKPIIVRW--EKEDRIINPEMARYLVSTKEVGEEVISTLQILPT 855
Query: 678 VHYT---FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLR 734
V F AIN YG + + TV P PE DVK IT +
Sbjct: 856 VREDSGFFSCHAINSYGE-DRGIIQLTVQEPPDPPEIEIKDVKAR-------TITLRWTM 907
Query: 735 WMDWNAPQVQYRVQ-------WRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVN 787
D N+P Y ++ W Q+ S + + +ST Y I++ A N
Sbjct: 908 GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSST---YSIRMYAKN 964
Query: 788 SQGKG-PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVT 846
GK P ++TI + E P P+ +E ++S ++ V W+ G +RGY +
Sbjct: 965 RIGKSEPSNELTI-TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIG 1023
Query: 847 YWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFT 905
Y RE S + + +I V ++ L L ++ Y L VQA N G+GP+S E
Sbjct: 1024 Y-REYSTGGNFQFNIIS--VDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEII 1080
Query: 906 FSTPEGVPGH-PEALHLECQSNTSLLLRWQPPLSH--NGVLTGY-VLSYHPLDEGGKGQL 961
+T E VP + PE + S S+ + W NG+L G+ V+ + L +G G++
Sbjct: 1081 TTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEI 1140
Query: 962 -SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG---EAI---VREGGTMALSGISD 1014
+ P L L L + Y Q+ A T+ G G E I +E +G+
Sbjct: 1141 KNITTTQPSL---ELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVK- 1196
Query: 1015 FGNISATAGENYSVVSWVP 1033
+A A + VSW+P
Sbjct: 1197 ----AAAASASMVFVSWLP 1211
Score = 100 bits (249), Expect = 9e-21
Identities = 140/606 (23%), Positives = 218/606 (35%), Gaps = 49/606 (8%)
Query: 24 EELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW---TRDGV-------HFKP 73
E+L S + +V T + C A+G P V RW T + + H P
Sbjct: 18 EDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHP 77
Query: 74 KEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKW 133
L ++ P S T+ +N+ Y C A N G S ++ + A +
Sbjct: 78 NGTL--QIFPFPPSSFSTLIHDNT---------YYCTAENPSGKIRSQDVHIKAVLREPY 126
Query: 134 PKETVKPVEVEEGESVVLPCNPPPSAEP-LRIYWMNSKILHIKQDERVTMGQNGNLYFAN 192
V+ + G V C P S E + + + + R + G LY +
Sbjct: 127 TVR-VEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKD 185
Query: 193 VLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQG 252
V D +Y C T Q L V + + P +L + H A+ G
Sbjct: 186 VQNEDGLYNYRCITRHRYTGETRQSNSARLFV---SDPANSAPSIL---DGFDHRKAMAG 239
Query: 253 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENS 312
Q + L C A G P P +WL+ + P+ +Q L + + D G Y C N
Sbjct: 240 QRVELPCKALGHPEPDYRWLKDNMPLELSG-RFQKTVTGLLIENIRPSDSGSYVCEVSNR 298
Query: 313 LGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELA 372
G+A+ + V+ P+ G L C V G E++W NG +
Sbjct: 299 YGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGK 358
Query: 373 KDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV--QLPAKILTADNQT 430
+ I LI+ ++ SD QC R L A Y+ VV KI++A ++
Sbjct: 359 NVRITGINHENLIMDHMVKSDGGAYQCFVRK--DKLSAQDYVQVVLEDGTPKIISAFSEK 416
Query: 431 YMAVQGSTAYLLCKAFGAPVPSVQW-LDEDGTTVLQDERFFPYANGT------LGIRDLQ 483
++ L+C G P+P++ W LD+D R L I Q
Sbjct: 417 VVS-PAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQ 475
Query: 484 ANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFT-CQASFDPSL 542
D G Y C A N V A + V+ I P I R T+ C+ P
Sbjct: 476 VRDGGVYRCTANNSAGVVLYQARINVRGPASIR--PMKNITAIAGRDTYIHCRVIGYPYY 533
Query: 543 QPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYS-DQGNYSCVASTELDVVESRAQL 601
SI W + +L F +G L + + D+G Y+C + + S++
Sbjct: 534 --SIKWYKNS-NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVH 590
Query: 602 LVVGSP 607
+ V P
Sbjct: 591 VTVKVP 596
Score = 76.6 bits (187), Expect = 1e-13
Identities = 69/286 (24%), Positives = 113/286 (39%), Gaps = 16/286 (5%)
Query: 530 VTFTCQASFDPSLQPSITWRGDGRDLQELG--DSDKYFIEDGRLVIHSLDYSDQGNYSCV 587
+ C+A DPS P++ W D L D + +G +I ++ D G YSC+
Sbjct: 1303 IVLPCKAVGDPS--PAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCI 1360
Query: 588 ASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEF 647
A+ E L V P PRL +S T S + +SW P ++ + I Y +++
Sbjct: 1361 ANNNWGSDEIILNLQVQVPPDQ-PRLTVSKT---TSSSITLSWLPGDNGGSSIRGYILQY 1416
Query: 648 EDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEA 707
+ E+W S P ++ L Y F +TA N GPG S + E +
Sbjct: 1417 SEDNS--EQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE 1474
Query: 708 APEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS-DP 766
++ N T + + W D P + +++RP GT Q S
Sbjct: 1475 PQFSKEQELFASINTTR---VRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSK 1531
Query: 767 FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQ--VTIGYSGEDYPQAI 810
++ + YE++++ NS G + T+ Y G P I
Sbjct: 1532 SYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLI 1577
Score = 55.8 bits (133), Expect = 2e-07
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 416 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQ--DERFFPY 472
+ + PA+ILT T L CKA G P P+V+W+ D +GT L D R +
Sbjct: 1281 LAKAPARILTFSG-TVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF 1339
Query: 473 ANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGS 528
+NG+ IR ++A D+G Y C+A N+ + I+ NL+V+ PR T+ K S
Sbjct: 1340 SNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP---PDQPRLTVSKTTS 1392
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 255 LVLECIAEGFPTPTIKWLRPSGPMPA------DRVTYQNHNKTLQLLKVGEEDDGEYRCL 308
+VL C A G P+P +KW++ S P+ R + N + ++ +K ED G Y C+
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSCI 1360
Query: 309 AENSLGSARHAYYVTVEAAP 328
A N+ GS + V+ P
Sbjct: 1361 ANNNWGSDEIILNLQVQVPP 1380
Score = 40.8 bits (94), Expect = 0.008
Identities = 91/415 (21%), Positives = 149/415 (35%), Gaps = 34/415 (8%)
Query: 674 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 733
L Y +Y+ +V A + G G S T T E P P VK + + ++W P
Sbjct: 1155 LEKYTNYSIQVLAFTRAGDGVRSEQIFTR-TKEDVPGP-PAGVKAAAASASMVFVSWLPP 1212
Query: 734 RWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLV-VSNTSTFVPYEIKVQAVNSQGKG 792
+ N +Y V + + D F + N S Y + V AV S G+G
Sbjct: 1213 --LKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRG 1270
Query: 793 PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGS 852
++ P I G V W + K W + S
Sbjct: 1271 NSSEIITVEPLAKAPARILTFSG-------TVTTPWMKDIVLPCKAVGDPSPAVKWMKDS 1323
Query: 853 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGV 912
S I + + S I+ ++ S + A N GS E + V
Sbjct: 1324 NGTPSLVTIDGRRSIF--SNGSFIIRTVKAEDSGYYSCIANNNWGS---DEIILNLQVQV 1378
Query: 913 PGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRT 972
P L + +++S+ L W P + + GY+L Y ++ + SF + P R+
Sbjct: 1379 PPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS--EDNSEQWGSFPI-SPSERS 1435
Query: 973 HNLTDLSPHLRYRFQLQATTKEGPGE-AIVREGGTMALSGISD-----FGNISATAGENY 1026
+ L +L Y+F L A GPG + + E T+ F +I+ T
Sbjct: 1436 YRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTR-VRL 1494
Query: 1027 SVVSWVPKEGQCNF-RFHILFKALG----EEKGGASLSPQYVSYNQSSYTQWDLQ 1076
+++ W +G C F + ++ G SLS Y+ Y+ T ++LQ
Sbjct: 1495 NLIGW--NDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQ 1547
Score = 30.8 bits (68), Expect = 8.4
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 347 LDCQVQGRPQPEVTWR--INGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNR 404
L C+ G P P V W NG P ++ G+ I+ V+ D+ C A N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 405 HG 406
G
Sbjct: 1365 WG 1366
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 231 bits (590), Expect = 2e-60
Identities = 208/810 (25%), Positives = 342/810 (42%), Gaps = 74/810 (9%)
Query: 245 SHLVALQGQPLVLECIAEGFP-TPTIKWLRPSGPMPA--DRVTYQNHNKTLQLLKV---- 297
S V ++G ++L+C AE P IKW + + D Q N +L + +
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 298 -GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY----WLHKPQSHLYGPGETARLDCQVQ 352
+ D+G Y+C E SLG + T + A +L + +S G+T L C+V
Sbjct: 107 HHKPDEGLYQC--EASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVI 164
Query: 353 GRPQPEVTWRINGIPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQCEARNRHGLLLAN 411
G P P + W+ N + + D + + GAL +S +QP D + +C ARN N
Sbjct: 165 GEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGN 224
Query: 412 A-------------YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE 458
+Y +Q P+ ++ A++G A L C G P PS WL
Sbjct: 225 EAEVRILSDPGLHRQLYFLQRPSNVV--------AIEGKDAVLECCVSGYPPPSFTWLRG 276
Query: 459 DGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQG 518
+ L+ +++ L I ++ +D+G Y C+ N++ A L V
Sbjct: 277 EEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNH 336
Query: 519 PRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLD 577
P + + + F C S P P++ W +G + SD + I G L I +
Sbjct: 337 PSNLYAYESMDIEFECTVSGKPV--PTVNWMKNG---DVVIPSDYFQIVGGSNLRILGVV 391
Query: 578 YSDQGNYSCVASTELDVVESRAQLLV----VGSPGPVPRLVLSDLHLLTQSQ-VRVSWSP 632
SD+G Y CVA E ++ AQL+V + S +P + +L S+ VR+SW P
Sbjct: 392 KSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRP 451
Query: 633 AEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGP 692
+ I+ + + F + E+ + + PG+ T L P YTFRV A N++GP
Sbjct: 452 PAEAKGNIQTFTVFFSREGDNRERALNTTQ-PGSLQLTVGNLKPEAMYTFRVVAYNEWGP 510
Query: 693 GEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQ 752
GE S + PE +++ T+++ITW+P + N P YR+ + +
Sbjct: 511 GESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYA--NGPVQGYRL-FCTE 567
Query: 753 GTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPE 812
+ G Q V + F Y ++ A N G G + D P A P+
Sbjct: 568 VSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQ 627
Query: 813 LEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANT 872
+E++NS ++ V W P G + GY + +H K + + N
Sbjct: 628 NVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI---------RHRKTTRRGEMETLEPNN 678
Query: 873 TSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG------VPGHPEALHLECQS 925
+ +GL S Y +V A G+GP S +T TPE VP P +LH+ Q+
Sbjct: 679 LWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQT 738
Query: 926 NTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLR-DPELRTHNLTDLSPHLRY 984
N +++ W PPL+ N V+ GY++ Y G + +R D + R +++ L Y
Sbjct: 739 N-CIIMSWTPPLNPNIVVRGYIIGY-----GVGSPYAETVRVDSKQRYYSIERLESSSHY 792
Query: 985 RFQLQATTKEGPGEAIVREGGTMALSGISD 1014
L+A G G + T +++ +D
Sbjct: 793 VISLKAFNNAGEGVPLYESATTRSITDPTD 822
Score = 93.6 bits (231), Expect = 1e-18
Identities = 97/388 (25%), Positives = 162/388 (41%), Gaps = 24/388 (6%)
Query: 37 PRRLVVFPTDDISLKCEASGKPEVQ-FRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGN 95
P V ++ L C A V +W +DG+H LG+ + S + N
Sbjct: 46 PSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLA----LGMDERKQQLSNGSLLIQN 101
Query: 96 --NSNFAQRFQGIYRCFAS-NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLP 152
+S + +G+Y+C AS G+ +S ++ G ++ +T + V G++V+L
Sbjct: 102 ILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQT-ESVTAFMGDTVLLK 160
Query: 153 CNPPPSAEPLRIYWMNSK--ILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPG 210
C P I+W ++ + I D RV + +G L + + D Y C A P
Sbjct: 161 CEVIGEPMPT-IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDI-GIYRCSARNPA 218
Query: 211 T-RTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTI 269
+ RT + E +R+ + + R L+ S++VA++G+ VLEC G+P P+
Sbjct: 219 SSRTGNEAE---VRILSDPGL----HRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSF 271
Query: 270 KWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 328
WLR + Y L + V ++D G Y C+ + + +TV P
Sbjct: 272 TWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPP 331
Query: 329 YWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSN 388
++L+ P + +C V G+P P V W NG V + D + L +
Sbjct: 332 WFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVV--IPSDYFQIVGGSNLRILG 389
Query: 389 VQPSDTMVTQCEARNRHGLLLANAYIYV 416
V SD QC A N G +A + V
Sbjct: 390 VVKSDEGFYQCVAENEAGNAQTSAQLIV 417
Score = 68.9 bits (167), Expect = 3e-11
Identities = 102/433 (23%), Positives = 168/433 (38%), Gaps = 85/433 (19%)
Query: 618 LHLLTQSQVRVSW--SPAEDHNAPIEKYDIEF-------EDKEMAPEK-WYSL-GKVPGN 666
L ++ ++VSW P+ N I Y I E + + P WY G G+
Sbjct: 631 LEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGS 690
Query: 667 QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEG----NE 722
Q Y+F+V+A+ G G PS T TPE +++ V + +
Sbjct: 691 Q------------YSFQVSAMTVNGTGPPSNWY-TAETPENDLDESQVPDQPSSLHVRPQ 737
Query: 723 TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP---FLVVSNTSTFVPY 779
T ++++W P P + R G P+ E + D + + + Y
Sbjct: 738 TNCIIMSWTPPL-----NPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHY 792
Query: 780 EIKVQAVNSQGKG------------PEPQVTIGYSG--EDYPQAIPELE-------GIEI 818
I ++A N+ G+G +P + Y +D+P ++P+L G++
Sbjct: 793 VISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQA 852
Query: 819 --LNSSAVLVKW--RPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTS 874
L AV V W V Q +R Y V WR S ++ +D + S
Sbjct: 853 VALTHDAVRVSWADNSVPKNQKTSEVRLYTVR-WRTSFSA--SAKYKSED-----TTSLS 904
Query: 875 VILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST-----PEGVPGHPEALHLECQSNTSL 929
+GL+P + Y V R S S +T P P + E + ++
Sbjct: 905 YTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPR-AV 963
Query: 930 LLRWQPPLSHNGVLTGYVLSYH-----PLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRY 984
++ WQPPL NG +T Y+L Y P+D+ +S + TH + DL+ Y
Sbjct: 964 IVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETIS-----GDRLTHQIMDLNLDTMY 1018
Query: 985 RFQLQATTKEGPG 997
F++QA +G G
Sbjct: 1019 YFRIQARNSKGVG 1031
Score = 35.8 bits (81), Expect = 0.26
Identities = 55/230 (23%), Positives = 80/230 (34%), Gaps = 32/230 (13%)
Query: 35 QSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITG 94
Q P +V D L+C SG P F W R G V Q + G
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-----------GEEVIQLRSKKYSLLGG 292
Query: 95 NN---SNFAQRFQGIYRCFASNK-LGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVV 150
+N SN G+Y C + K + S E+ ++ P W + E +
Sbjct: 293 SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL---VPPWFLNHPSNLYAYESMDIE 349
Query: 151 LPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--- 207
C P + WM + + I D +G NL V+ SD Y C A
Sbjct: 350 FECTVSGKPVP-TVNWMKNGDVVIPSDYFQIVG-GSNLRILGVVKSD-EGFYQCVAENEA 406
Query: 208 ---FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQP 254
+ I+ K I ++S++ PR + P SS V L +P
Sbjct: 407 GNAQTSAQLIVPKPAI-----PSSSVLPSAPRDVVPVLVSSRFVRLSWRP 451
Score = 32.7 bits (73), Expect = 2.2
Identities = 58/322 (18%), Positives = 114/322 (35%), Gaps = 50/322 (15%)
Query: 616 SDLHLLTQSQ-VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-K 673
S LH+ Q+ + +SW+P + N + Y I + + +V Q ++ +
Sbjct: 730 SSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYG----VGSPYAETVRVDSKQRYYSIER 785
Query: 674 LSPYVHYTFRVTAINKYGPGEPSPVSETVVT-----------------PEAAPEKNPVDV 716
L HY + A N G G P S T + P + P+ + +
Sbjct: 786 LESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPML 845
Query: 717 KGEGNETTNMVITWKPLRWMDWNAPQVQ-------YRVQWRPQ-GTRGPWQEQIVSDPFL 768
G + + + W D + P+ Q Y V+WR ++ + +
Sbjct: 846 PPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSY 905
Query: 769 VVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSS----AV 824
+ YE V ++ + E P + P+ + ++ AV
Sbjct: 906 TATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPK--DLTVITREGKPRAV 963
Query: 825 LVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVV---VPANTTSVILSGLR 881
+V W+P + G + Y + Y + ++I D + + + + + L
Sbjct: 964 IVSWQPP--LEANGKITAYILFYTLD--------KNIPIDDWIMETISGDRLTHQIMDLN 1013
Query: 882 PYSSYHLEVQAFNGRGSGPASE 903
+ Y+ +QA N +G GP S+
Sbjct: 1014 LDTMYYFRIQARNSKGVGPLSD 1035
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 229 bits (583), Expect = 2e-59
Identities = 196/789 (24%), Positives = 340/789 (43%), Gaps = 72/789 (9%)
Query: 248 VALQGQPLVLECIAEGFPTPTIKW----------------LRPSGPMPADRVTYQNHNKT 291
++++G ++L C A P+P I+W L P G + V + HNK
Sbjct: 63 LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKP 122
Query: 292 LQLLKVGEEDDGEYRCLAE-NSLGS--ARHAYYVTVEAAPYWLHKPQSHLYGPGETARLD 348
D+G Y+C+A SLG+ +R A + V P + +P+ G A L+
Sbjct: 123 ---------DEGYYQCVATVESLGTIISRTAKLI-VAGLPRFTSQPEPSSVYAGNNAILN 172
Query: 349 CQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 408
C+V P V W N P+ L D+ ++ G L++SN D + +C + G
Sbjct: 173 CEVNADLVPFVRWEQNRQPL--LLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GPP 229
Query: 409 LANAYIYVVQLPAKILTAD------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGT 461
+ + + LP + +D + V G L C A G P P+++W+ +E+
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 462 TVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRS 521
ER A G+L I D+ +D G YFC+A N + A L V+ + + P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349
Query: 522 TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQ 581
+ + F C+ + P+ P++ W +G D+ D K +++ L + L SD+
Sbjct: 350 IYAHESMDIVFECEVTGKPT--PTVKWVKNG-DMVIPSDYFK-IVKEHNLQVLGLVKSDE 405
Query: 582 GNYSCVASTELDVVESRAQLLVV----GSPGPVPRLVLSDLHLLTQSQ-VRVSW-SPAED 635
G Y C+A ++ ++ AQL+++ + GP+P + L ++ ++++W +PA D
Sbjct: 406 GFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASD 465
Query: 636 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEP 695
+ Y + + + +A E+ + PG T L P Y FRV A NK+G GE
Sbjct: 466 PHGDNLTYSVFYTKEGIARERVENTSH-PGEMQVTIQNLMPATVYIFRVMAQNKHGSGES 524
Query: 696 SPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR 755
S PE +++ T++ +TW+ + N Y++ + +GT
Sbjct: 525 SAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETP--VSGNGEIQNYKLYYMEKGT- 581
Query: 756 GPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEG 815
Q+ VS ++ + Y +V A N G G + D P A P+
Sbjct: 582 DKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLS 641
Query: 816 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 875
+E+ NS ++++ W+P A G + GY + Y + + R +V S
Sbjct: 642 LEVRNSKSIMIHWQPPAPATQNGQITGYKIRY-------RKASRKSDVTETLVSGTQLSQ 694
Query: 876 ILSGLRPYSSYHLEVQAFNGRGSGPASEF----TFST---PEGVPGHPEALHLECQSNTS 928
++ GL + Y+ V A G+GPA+++ TF + VP P +LH+ TS
Sbjct: 695 LIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVR-PLVTS 753
Query: 929 LLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQL 988
+++ W PP + N V+ GY + Y G D + R + + +L P Y L
Sbjct: 754 IVVSWTPPENQNIVVRGYAIGYGI----GSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 809
Query: 989 QATTKEGPG 997
+A G G
Sbjct: 810 KAFNNVGEG 818
Score = 145 bits (365), Expect = 3e-34
Identities = 231/1037 (22%), Positives = 395/1037 (38%), Gaps = 121/1037 (11%)
Query: 36 SPRRLVVFPTDDIS-------LKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
+P +V P D +S L C A +P + W +DG + + P
Sbjct: 51 TPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLL--PDGS 108
Query: 89 SFTITGNNSNFAQRFQGIYRCFAS-NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 147
F +S + +G Y+C A+ LGT +S +L+ G P++ + +P V G
Sbjct: 109 LFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQP-EPSSVYAGN 167
Query: 148 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 207
+ +L C P + N + L + D+RV +G L +N D Y C
Sbjct: 168 NAILNCEVNADLVPFVRWEQNRQPLLL--DDRVIKLPSGMLVISNATEGDGGL-YRCVVE 224
Query: 208 FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTP 267
G + ++L+V +I L P S LV + GQ +VL C+A G PTP
Sbjct: 225 SGGPPKY--SDEVELKVLPDPEVISDLVFLKQP----SPLVRVIGQDVVLPCVASGLPTP 278
Query: 268 TIKWLRPSGPM---PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTV 324
TIKW++ + ++R+ +L++ V E+D G Y C+A+N + +TV
Sbjct: 279 TIKWMKNEEALDTESSERLVLL-AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTV 337
Query: 325 EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGAL 384
+A P +L +P + +C+V G+P P V W NG V + D ++ L
Sbjct: 338 QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV--IPSDYFKIVKEHNL 395
Query: 385 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ-LPAKI--LTADNQTYMAVQGSTAYL 441
+ + SD QC A N G A A + +++ PA L + + +A ST ++
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFI 455
Query: 442 -------LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLA 494
G + + ++G + E + I++L + +A
Sbjct: 456 KLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMA 515
Query: 495 ANDQNNVTIMANLKVKDATQI-TQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGR 553
N + A L+V+ ++ GP + + T ++TW
Sbjct: 516 QNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT-----------SITVTWETPVS 564
Query: 554 DLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGP---- 609
E+ + Y++E G +D S ++S + E +++ GP
Sbjct: 565 GNGEIQNYKLYYMEKGTDKEQDVDVS---SHSYTINGLKKYTEYSFRVVAYNKHGPGVST 621
Query: 610 --VPRLVLSD----------LHLLTQSQVRVSWSP--AEDHNAPIEKYDIEFEDKEMAPE 655
V LSD L + + + W P N I Y I + +
Sbjct: 622 PDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSD 681
Query: 656 KWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPV 714
+L V G Q S ++ L Y FRV A+ G G + E
Sbjct: 682 VTETL--VSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP 739
Query: 715 DVKGEGNE---TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFL 768
+V + T++V++W P + N Y + + G P + I D +
Sbjct: 740 EVPSSLHVRPLVTSIVVSWTPPE--NQNIVVRGYAIGY---GIGSPHAQTIKVDYKQRYY 794
Query: 769 VVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV-- 826
+ N Y I ++A N+ G+G + + S P + ++N+ V
Sbjct: 795 TIENLDPSSHYVITLKAFNNVGEG----IPLYESAVTRPHTDTSEVDLFVINAPYTPVPD 850
Query: 827 ---KWRPVDL-AQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVV-----VPAN------ 871
PV + A + H +T W + S KH K + + V +PAN
Sbjct: 851 PTPMMPPVGVQASILSH-DTIRIT-WADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNA 908
Query: 872 ---TTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST-----PEGVPGHPEALHLEC 923
T S +++GL+P + Y V GR S S T P P + E
Sbjct: 909 NATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 924 QSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPEL---RTHNLTDLSP 980
+ T +++ WQPP NG +TGY++ Y ++ + +P + TH + +L+
Sbjct: 969 KPKT-IIVNWQPPSEANGKITGYIIYY---STDVNAEIHDWVIEPVVGNRLTHQIQELTL 1024
Query: 981 HLRYRFQLQATTKEGPG 997
Y F++QA +G G
Sbjct: 1025 DTPYYFKIQARNSKGMG 1041
Score = 52.4 bits (124), Expect = 3e-06
Identities = 79/344 (22%), Positives = 130/344 (37%), Gaps = 78/344 (22%)
Query: 614 VLSDLHLLTQ-SQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLG-------KVPG 665
V S LH+ + + VSW+P E+ N + Y I Y +G KV
Sbjct: 741 VPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIG-----------YGIGSPHAQTIKVDY 789
Query: 666 NQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVT-------------------- 704
Q T++ L P HY + A N G G P+ E+ VT
Sbjct: 790 KQRYYTIENLDPSSHYVITLKAFNNVGEG--IPLYESAVTRPHTDTSEVDLFVINAPYTP 847
Query: 705 -PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQ-------YRVQWR---PQG 753
P+ P PV V+ + ITW D + P+ Q Y V+W+ P
Sbjct: 848 VPDPTPMMPPVGVQASILSHDTIRITWA-----DNSLPKHQKITDSRYYTVRWKTNIPAN 902
Query: 754 TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPEL 813
T+ ++ + +V+ YE V + G + E P + P+
Sbjct: 903 TK--YKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPK- 959
Query: 814 EGIEILNSSA----VLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVP 869
+ +++ ++V W+P ++ G + GY + Y + + H D V+ P
Sbjct: 960 -DVTVVSKEGKPKTIIVNWQPP--SEANGKITGYIIYYSTDVNAEIH-------DWVIEP 1009
Query: 870 A--NTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPE 910
N + + L + Y+ ++QA N +G GP SE F TP+
Sbjct: 1010 VVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPK 1053
Score = 38.1 bits (87), Expect = 0.053
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
Query: 35 QSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITG 94
+ P + + DI +CE +GKP +W ++G P + ++ + + G
Sbjct: 345 KQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD-----YFKIVKEHNLQVLG 399
Query: 95 NNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
+ +G Y+C A N +G A + ++ E AP
Sbjct: 400 ----LVKSDEGFYQCIAENDVGNAQAGAQLIILEHAP 432
Score = 32.3 bits (72), Expect = 2.9
Identities = 37/158 (23%), Positives = 62/158 (39%), Gaps = 18/158 (11%)
Query: 26 LMEPPVITE----QSPRRLVVFPTDDISLKCEASGKPEVQFRWTR--DGVHFKPKEELGV 79
L +P VI++ + P LV D+ L C ASG P +W + + + + E L +
Sbjct: 240 LPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVL 299
Query: 80 TVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVK 139
GS I S+ + G Y C A N T + + L + P++ K+
Sbjct: 300 LA-----GGSLEI----SDVTEDDAGTYFCIADNGNET-IEAQAELTVQAQPEFLKQPTN 349
Query: 140 PVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQD 177
+ E +V C P + W+ + + I D
Sbjct: 350 -IYAHESMDIVFECEVTGKPTP-TVKWVKNGDMVIPSD 385
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 205 bits (521), Expect = 3e-52
Identities = 246/1033 (23%), Positives = 399/1033 (38%), Gaps = 86/1033 (8%)
Query: 30 PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGS 89
P+ +P++L + L C +G PE RW R+ P E + + + + +
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISI---RGLSNET 430
Query: 90 FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESV 149
IT + + G Y+CFA+ K TA I + +G P+ + V V GE
Sbjct: 431 LLITSAQKSHS----GAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQF 485
Query: 150 VLPCNPPPSAEPLRIYWMNSKILHIKQDERV---TMGQNGNLYFANVLTSDNHSD---YI 203
L C + P + ++ + + R TM + NV T D Y
Sbjct: 486 SLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNV-TGPQIRDGGVYR 544
Query: 204 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 263
C A R ++ R+ R R ++ A+ G+ ++ C G
Sbjct: 545 CTA-----RNLVGSAEYQARINVRGPPSIRAMR---------NITAVAGRDTLINCRVIG 590
Query: 264 FPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE-DDGEYRC--LAENSLGSARHAY 320
+P +IKW + + +P + N TL+L V + D+GEY C L + L S +
Sbjct: 591 YPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQL-SISQSV 649
Query: 321 YVTVEAAPYWLHKPQSHLYGP---GETARLDCQVQGRPQP-EVTWRING-IPVEELAKDQ 375
+V V+ P Q + P G+ + C V P +TWR +G + +
Sbjct: 650 HVAVKVPPLI----QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTI 705
Query: 376 KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ 435
+ + +L +S+V C A N + + V P ++ +NQ +
Sbjct: 706 ESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIY 763
Query: 436 GSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA-------NGTLGIRDLQANDTG 488
G L C G P P V W G+ Q P N +L IR + D G
Sbjct: 764 GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIG 823
Query: 489 RYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSIT 547
Y C A+N +++ L VK IT P +TI KG C A + +P I
Sbjct: 824 YYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGE---RPIII 880
Query: 548 WRGDGRDLQELGDSDKYFI---EDGRLVIHSL-----DYSDQGNYSCVASTELDVVESRA 599
G + + +Y I ++G V+ +L D D +SC A
Sbjct: 881 RWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLI 940
Query: 600 QLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYS 659
QL V P P P L + ++ + + + W+ D N+ I +DIE+++K + + S
Sbjct: 941 QLTVQEPPDP-PELEIREVKARSMN---LRWTQRFDGNSIITGFDIEYKNKSDSWDFKQS 996
Query: 660 LGKV-PGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKG 718
+ P + + L P Y+ R+ + NK G EPS T+ T EAAP+ P+DV
Sbjct: 997 TRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSK-ELTISTEEAAPDGPPMDVTL 1055
Query: 719 EGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS------DPFLVVSN 772
+ + ++ +TWK + N Y++ +R Q IV + N
Sbjct: 1056 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1115
Query: 773 TSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVD 832
F Y + VQA N G GP + ED P PE + S ++ W
Sbjct: 1116 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1175
Query: 833 LAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQA 892
+ + G L+GY V +W + + + V L G+ +++Y ++V A
Sbjct: 1176 RSTLNGVLKGYRVIFWSLYVDGEWGEMQ------NITTTRERVELRGMEKFTNYSVQVLA 1229
Query: 893 FNGRGSGPASEFTF-STPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH 951
+ G G S + T E VPG P + S +S+++ W PP NGV+ Y +
Sbjct: 1230 YTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCS 1289
Query: 952 PLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG---EAIVREGGTMA 1008
G + PE + + L+ +Y + A T G G E + E A
Sbjct: 1290 SPGSGQPAPSEYE-TSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKA 1348
Query: 1009 LSGISDFGNISAT 1021
+ I FG T
Sbjct: 1349 PAKIISFGGTVTT 1361
Score = 105 bits (263), Expect = 2e-22
Identities = 138/585 (23%), Positives = 220/585 (37%), Gaps = 48/585 (8%)
Query: 23 PEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVY 82
PE++ S +++ + + + C A+G P RW G +Y
Sbjct: 78 PEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYL---------ATGDDIY 128
Query: 83 QSPH------SGSFTITGNNSNFAQRF--QGIYRCFASNKLGTAMSHEIRLMAEGAPKWP 134
PH +G+ + + + F Y C A N G S IR+ A +
Sbjct: 129 DVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYT 188
Query: 135 KETVKPVEVEEGESVVLPCNPPPSA-EPLRIYWMNSKILHIKQDERVTMGQNGNLYFANV 193
V+ G V C P S E + + + I + R + +G LY ++V
Sbjct: 189 VR-VEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDV 247
Query: 194 LTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQ 253
D S Y C + Q L V I P +L +S G
Sbjct: 248 QKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESI---PTILDGFHSQE---VWAGH 301
Query: 254 PLVLECIAEGFPTPTIKWLRPSGPMPAD-RVTYQNHNKTLQLLKVGEEDDGEYRCLAENS 312
+ L C A G+P P I+WL+ P+PAD R T + T+ L+ ED G Y C N+
Sbjct: 302 TVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRT--EDSGTYICEVTNT 359
Query: 313 LGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELA 372
GSA + V + P+ G G T L C + G P+ + W N E +
Sbjct: 360 FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRN---TELVL 416
Query: 373 KDQKYRIQ---RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 429
D+ I+ L++++ Q S + QC A + A I + +I+++ ++
Sbjct: 417 PDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 476
Query: 430 TYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDE---RFFPYANGT----LGIRDL 482
+ G L+C A GAP P+V W +D V + ++GT + +
Sbjct: 477 K-VVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGP 535
Query: 483 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSL 542
Q D G Y C A N + A + V+ I + R+ G C+ P
Sbjct: 536 QIRDGGVYRCTARNLVGSAEYQARINVRGPPSI-RAMRNITAVAGRDTLINCRVIGYPYY 594
Query: 543 QPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYS-DQGNYSC 586
SI W D L + + + E+G L + + D+G Y C
Sbjct: 595 --SIKWYKDALLLPD--NHRQVVFENGTLKLTDVQKGMDEGEYLC 635
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/288 (23%), Positives = 118/288 (40%), Gaps = 27/288 (9%)
Query: 530 VTFTCQASFDPSLQPSITWRGDGRD--LQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCV 587
V C + DP+ P++ W D D + D + +G L++ ++ D G Y+C
Sbjct: 1367 VRLPCNSVGDPA--PAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCT 1424
Query: 588 ASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEF 647
A T ++ L+V P PRL +S + S + ++W P ++ + I + +++
Sbjct: 1425 A-TNTGGFDTIIVNLLVQVPPDQPRLTVSK---TSASSITLTWIPGDNGGSSIRGFVLQY 1480
Query: 648 EDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEA 707
E+W + ++ L Y ++ A N G G +SE + EA
Sbjct: 1481 SVDN--SEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR---ISEII---EA 1532
Query: 708 APEKNPVDVKGEGNETTNMVITWKPLRWMDWN---APQVQYRVQWRPQGTRGPWQ---EQ 761
+ + T++ T L WN P +++RP+GT WQ
Sbjct: 1533 KTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGT-WAWQGLRAN 1591
Query: 762 IVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQ--VTIGYSGEDYP 807
+ FL +T+ YE++++A NS G G E T+ Y G P
Sbjct: 1592 SSGEVFLTELREATW--YELRMRACNSAGCGNETAQFATLDYDGSTIP 1637
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 8/118 (6%)
Query: 420 PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL---DEDGTTVLQDERFFPYANGT 476
PAKI++ T L C + G P P+V+W ++ V D + NGT
Sbjct: 1349 PAKIISFGG-TVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT 1407
Query: 477 LGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK-KGSRVTFT 533
L +R ++A D+G Y C A N TI+ NL V+ PR T+ K S +T T
Sbjct: 1408 LLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP---PDQPRLTVSKTSASSITLT 1462
Score = 47.8 bits (112), Expect = 7e-05
Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 20/218 (9%)
Query: 399 CEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQGSTAYLLC---KAFGAPVPSVQ 454
C A N G + + N + V + ++Q M +G+ A C + V V
Sbjct: 163 CTAENAAGKIRSPNIRVKAVFREPYTVRVEDQRSM--RGNVAVFKCLIPSSVQEYVSVVS 220
Query: 455 WLDEDGTTVLQDERFFPYANGTLGIRDLQANDT-GRYFCLAANDQNNVTIMAN---LKVK 510
W ++D +++ + RFF +G L I D+Q D Y C+ + + T +N L V
Sbjct: 221 W-EKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVT 279
Query: 511 DATQ----ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI 566
D + I G S G V C AS P P+I W DGR L ++
Sbjct: 280 DPAESIPTILDGFHSQEVWAGHTVELPCTASGYPI--PAIRWLKDGRPLPA---DSRWTK 334
Query: 567 EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVV 604
L I L D G Y C + E+ L+V+
Sbjct: 335 RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 372
Score = 37.7 bits (86), Expect = 0.069
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 257 LECIAEGFPTPTIKWLRPSG----PMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENS 312
L C + G P P +KW + S P+ D + N TL L V ED G Y C A N+
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNT 1428
Query: 313 LG 314
G
Sbjct: 1429 GG 1430
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 204 bits (518), Expect = 6e-52
Identities = 224/865 (25%), Positives = 356/865 (41%), Gaps = 95/865 (10%)
Query: 113 NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKIL 172
N LG S RL E P E + V +GE L C P ++ + +
Sbjct: 52 NSLGYTGS---RLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV 108
Query: 173 HIKQDERVT---MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVK 225
+D+ + + +G+L+F ++ + + Y+C A + +++ +
Sbjct: 109 ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAIL 168
Query: 226 ATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPA--DR 282
+ F N S +VA+ G+P V+EC G P PTI W + P+ +R
Sbjct: 169 RDD----------FRQNPSDVMVAV-GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER 217
Query: 283 VTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGP 341
+T + L + + D G+Y C+ N +G +TV P ++ +P +
Sbjct: 218 ITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV 275
Query: 342 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEA 401
++A C+ +G P P V WR + EL K + L + V D C A
Sbjct: 276 DDSAEFKCEARGDPVPTVRWRKDD---GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVA 332
Query: 402 RNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGT 461
N G A+A + V + P ++ +Q + G T C+A G P P++ W E
Sbjct: 333 ENMVGKAEASATLTVQEPPHFVVKPRDQ--VVALGRTVTFQCEATGNPQPAIFWRREGSQ 390
Query: 462 TVL-------QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ 514
+L RF G L I ++Q +D G Y C N ++ A L+V D
Sbjct: 391 NLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIA 450
Query: 515 ------ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIED 568
I QGP + +C A+ P P+I WR DG L DS +E+
Sbjct: 451 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGV-LVSTQDSRIKQLEN 507
Query: 569 GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV------VGSPGPV-PRLVLS----- 616
G L I D G Y+C+AST A + V V P P P L+ S
Sbjct: 508 GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKP 567
Query: 617 DLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP 676
++ ++++ V +SW P + A Y IE + W ++ + +TS L P
Sbjct: 568 EVTDVSRNTVTLSWQPNLNSGATPTSYIIE-AFSHASGSSWQTVAENVKTETSAIKGLKP 626
Query: 677 YVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI-------- 728
Y F V A N YG +PS +S+ V T + P VD K E N V+
Sbjct: 627 NAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVL 686
Query: 729 --TWKPLRW-MDWNAPQVQ-YRVQWRPQGT---RGPWQEQIVSDP---FLVVSNTSTFVP 778
+ + W +D + +Q Y++ +RP G W V P +V+ + V
Sbjct: 687 SSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVN 746
Query: 779 YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEIL----NSSAVLVKWRPVDLA 834
YEIK + ++ +G + ++ + E+ P A P +G+ + N +A+LV W+P
Sbjct: 747 YEIKARPFFNEFQGADSEIKFAKTLEEAPSAPP--QGVTVSKNDGNGTAILVSWQPPPED 804
Query: 835 QVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN 894
G ++ Y V W G++ ++ HI+K V +T SV++ L P Y +EV A
Sbjct: 805 TQNGMVQEYKV--WCLGNETRY---HINK---TVDGSTFSVVIPFLVPGIRYSVEVAAST 856
Query: 895 GRGSGPASE--FTFSTPEGVPGHPE 917
G GSG SE F G P PE
Sbjct: 857 GAGSGVKSEPQFIQLDAHGNPVSPE 881
Score = 191 bits (486), Expect = 3e-48
Identities = 148/509 (29%), Positives = 227/509 (44%), Gaps = 35/509 (6%)
Query: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
PP I E P L+V + +L C+A G+P W + G + ++ + SG
Sbjct: 67 PPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 125
Query: 89 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 147
S F + + ++ +G+Y C A N LG A+SH L ++ V V GE
Sbjct: 126 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGE 185
Query: 148 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 207
V+ C PP I W +DER+T+ + G L SD Y+C
Sbjct: 186 PAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYTRKSDA-GKYVC--- 240
Query: 208 FPGTRTIIQKEP--IDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 265
GT + ++E +L V S + R L + S+ +C A G P
Sbjct: 241 -VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEF----------KCEARGDP 289
Query: 266 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 325
PT++W + G +P R ++ + TL++ KV D G Y C+AEN +G A + +TV+
Sbjct: 290 VPTVRWRKDDGELPKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 348
Query: 326 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYRI- 379
P+++ KP+ + G T C+ G PQP + WR G + ++ +
Sbjct: 349 EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVS 408
Query: 380 QRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL----PAKILTAD--NQTYMA 433
Q G L ++NVQ SD C+ N G ++ AY+ V + P ++ NQT +A
Sbjct: 409 QTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT-VA 467
Query: 434 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCL 493
V G T L C A G+PVP++ W + QD R NG L IR + DTGRY C+
Sbjct: 468 VDG-TFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 526
Query: 494 AANDQNNVTIMANLKVKDATQITQGPRST 522
A+ T A ++V++ Q PR T
Sbjct: 527 ASTPSGEATWSAYIEVQEFGVPVQPPRPT 555
Score = 174 bits (441), Expect = 5e-43
Identities = 201/825 (24%), Positives = 338/825 (40%), Gaps = 87/825 (10%)
Query: 232 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 291
D PR++ S L+ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 65 DFPPRIV---EHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 121
Query: 292 LQ-----LLKV-----GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY---WLHKPQSHL 338
L L++ D+G Y C+A N LG A ++ ++E A + P +
Sbjct: 122 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAV-SHNASLEVAILRDDFRQNPSDVM 180
Query: 339 YGPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT 397
GE A ++CQ +G P+P ++W+ +G P+++ KD++ I+ G L+++ + SD
Sbjct: 181 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDD--KDERITIRGGKLMITYTRKSDAGKY 238
Query: 398 QCEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL 456
C N G + A + V++ P+ + N +A C+A G PVP+V+W
Sbjct: 239 VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEARGDPVPTVRWR 296
Query: 457 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 516
+DG L R+ + TL IR + A D G Y C+A N A L V++
Sbjct: 297 KDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 354
Query: 517 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFI-EDGR 570
PR + G VTF C+A+ +P QP+I WR +G Q S ++ + + G
Sbjct: 355 VKPRDQVVALGRTVTFQCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD 412
Query: 571 LVIHSLDYSDQGNYSCVASTELDVVESRAQLLV----------VGSPGPVPRLVLSDLHL 620
L I ++ SD G Y C + ++A L V V GPV + V D
Sbjct: 413 LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTF 472
Query: 621 LTQSQVRVSWSPA---EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPY 677
+ S P + D + E + K+ T + +P
Sbjct: 473 VLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQ-IRYAKLGDTGRYTCIASTPS 531
Query: 678 VHYTFRV-TAINKYG-PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
T+ + ++G P +P ++ + P A + DV + ++W+P
Sbjct: 532 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVS-----RNTVTLSWQPN-- 584
Query: 736 MDWNAPQVQYRVQWRPQGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGP 793
++ A Y ++ + WQ + V + Y V+A N+ G
Sbjct: 585 LNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 644
Query: 794 EPQVTIGYS---------GEDYPQ-------AIPELEGIEILNSSAVLVKWRPVDLAQVK 837
Q++ G D+ Q A+ L +L+SS++ V W + Q
Sbjct: 645 PSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT---VDQQS 701
Query: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
+++GY + Y G+ S + + V PA SV++ LR +Y ++ + F
Sbjct: 702 QYIQGYKILYRPSGANHGESDWLVFE--VRTPAKN-SVVIPDLRKGVNYEIKARPFFNEF 758
Query: 898 SGPASEFTFS-TPEGVPGHPE---ALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 953
G SE F+ T E P P + + T++L+ WQPP G V Y
Sbjct: 759 QGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP--PEDTQNGMVQEYKVW 816
Query: 954 DEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
G + + N D + + L P +RY ++ A+T G G
Sbjct: 817 CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 861
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 203 bits (517), Expect = 7e-52
Identities = 220/854 (25%), Positives = 352/854 (41%), Gaps = 92/854 (10%)
Query: 124 RLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT-- 181
RL E P E + V +GE L C P ++ + + +D+ +
Sbjct: 21 RLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR 80
Query: 182 -MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPR 236
+ +G+L+F ++ + + Y+C A + +++ + +
Sbjct: 81 MLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD-------- 132
Query: 237 LLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPA--DRVTYQNHNKTLQ 293
F N S +VA+ G+P V+EC G P PTI W + P+ +R+T + L
Sbjct: 133 --FRQNPSDVMVAV-GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK--LM 187
Query: 294 LLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQ 352
+ + D G+Y C+ N +G +TV P ++ +P + ++A C+ +
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR 247
Query: 353 GRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANA 412
G P P V WR + EL K + L + V D C A N G A+A
Sbjct: 248 GDPVPTVRWRKDD---GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Query: 413 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-------Q 465
+ V + P ++ +Q + G T C+A G P P++ W E +L
Sbjct: 305 TLTVQEPPHFVVKPRDQ--VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQS 362
Query: 466 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ------ITQGP 519
RF G L I ++Q +D G Y C N ++ A L+V D I QGP
Sbjct: 363 SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGP 422
Query: 520 RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYS 579
+ +C A+ P P+I WR DG L DS +E+G L I
Sbjct: 423 VNQTVAVDGTFVLSCVATGSPV--PTILWRKDGV-LVSTQDSRIKQLENGVLQIRYAKLG 479
Query: 580 DQGNYSCVASTELDVVESRAQLLV------VGSPGPV-PRLVLS-----DLHLLTQSQVR 627
D G Y+C+AST A + V V P P P L+ S ++ ++++ V
Sbjct: 480 DTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVT 539
Query: 628 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 687
+SW P + A Y IE + W ++ + +TS L P Y F V A
Sbjct: 540 LSWQPNLNSGATPTSYIIE-AFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAA 598
Query: 688 NKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI----------TWKPLRW-M 736
N YG +PS +S+ V T + P VD K E N V+ + + W +
Sbjct: 599 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTV 658
Query: 737 DWNAPQVQ-YRVQWRPQGT---RGPWQEQIVSDP---FLVVSNTSTFVPYEIKVQAVNSQ 789
D + +Q Y++ +RP G W V P +V+ + V YEIK + ++
Sbjct: 659 DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNE 718
Query: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEIL----NSSAVLVKWRPVDLAQVKGHLRGYNV 845
+G + ++ + E+ P A P +G+ + N +A+LV W+P G ++ Y V
Sbjct: 719 FQGADSEIKFAKTLEEAPSAPP--QGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV 776
Query: 846 TYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-- 903
W G++ ++ HI+K V +T SV++ L P Y +EV A G GSG SE
Sbjct: 777 --WCLGNETRY---HINK---TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQ 828
Query: 904 FTFSTPEGVPGHPE 917
F G P PE
Sbjct: 829 FIQLDAHGNPVSPE 842
Score = 191 bits (486), Expect = 3e-48
Identities = 148/509 (29%), Positives = 227/509 (44%), Gaps = 35/509 (6%)
Query: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
PP I E P L+V + +L C+A G+P W + G + ++ + SG
Sbjct: 28 PPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 89 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 147
S F + + ++ +G+Y C A N LG A+SH L ++ V V GE
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGE 146
Query: 148 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 207
V+ C PP I W +DER+T+ + G L SD Y+C
Sbjct: 147 PAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYTRKSDA-GKYVC--- 201
Query: 208 FPGTRTIIQKEP--IDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 265
GT + ++E +L V S + R L + S+ +C A G P
Sbjct: 202 -VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEF----------KCEARGDP 250
Query: 266 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 325
PT++W + G +P R ++ + TL++ KV D G Y C+AEN +G A + +TV+
Sbjct: 251 VPTVRWRKDDGELPKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309
Query: 326 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYRI- 379
P+++ KP+ + G T C+ G PQP + WR G + ++ +
Sbjct: 310 EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVS 369
Query: 380 QRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL----PAKILTAD--NQTYMA 433
Q G L ++NVQ SD C+ N G ++ AY+ V + P ++ NQT +A
Sbjct: 370 QTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT-VA 428
Query: 434 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCL 493
V G T L C A G+PVP++ W + QD R NG L IR + DTGRY C+
Sbjct: 429 VDG-TFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 487
Query: 494 AANDQNNVTIMANLKVKDATQITQGPRST 522
A+ T A ++V++ Q PR T
Sbjct: 488 ASTPSGEATWSAYIEVQEFGVPVQPPRPT 516
Score = 174 bits (441), Expect = 5e-43
Identities = 201/825 (24%), Positives = 338/825 (40%), Gaps = 87/825 (10%)
Query: 232 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 291
D PR++ S L+ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 26 DFPPRIV---EHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 82
Query: 292 LQ-----LLKV-----GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY---WLHKPQSHL 338
L L++ D+G Y C+A N LG A ++ ++E A + P +
Sbjct: 83 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAV-SHNASLEVAILRDDFRQNPSDVM 141
Query: 339 YGPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT 397
GE A ++CQ +G P+P ++W+ +G P+++ KD++ I+ G L+++ + SD
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDD--KDERITIRGGKLMITYTRKSDAGKY 199
Query: 398 QCEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL 456
C N G + A + V++ P+ + N +A C+A G PVP+V+W
Sbjct: 200 VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEARGDPVPTVRWR 257
Query: 457 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 516
+DG L R+ + TL IR + A D G Y C+A N A L V++
Sbjct: 258 KDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 315
Query: 517 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFI-EDGR 570
PR + G VTF C+A+ +P QP+I WR +G Q S ++ + + G
Sbjct: 316 VKPRDQVVALGRTVTFQCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD 373
Query: 571 LVIHSLDYSDQGNYSCVASTELDVVESRAQLLV----------VGSPGPVPRLVLSDLHL 620
L I ++ SD G Y C + ++A L V V GPV + V D
Sbjct: 374 LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTF 433
Query: 621 LTQSQVRVSWSPA---EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPY 677
+ S P + D + E + K+ T + +P
Sbjct: 434 VLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQ-IRYAKLGDTGRYTCIASTPS 492
Query: 678 VHYTFRV-TAINKYG-PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
T+ + ++G P +P ++ + P A + DV + ++W+P
Sbjct: 493 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVS-----RNTVTLSWQPN-- 545
Query: 736 MDWNAPQVQYRVQWRPQGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGP 793
++ A Y ++ + WQ + V + Y V+A N+ G
Sbjct: 546 LNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 605
Query: 794 EPQVTIGYS---------GEDYPQ-------AIPELEGIEILNSSAVLVKWRPVDLAQVK 837
Q++ G D+ Q A+ L +L+SS++ V W + Q
Sbjct: 606 PSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT---VDQQS 662
Query: 838 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 897
+++GY + Y G+ S + + V PA SV++ LR +Y ++ + F
Sbjct: 663 QYIQGYKILYRPSGANHGESDWLVFE--VRTPAKN-SVVIPDLRKGVNYEIKARPFFNEF 719
Query: 898 SGPASEFTFS-TPEGVPGHPE---ALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 953
G SE F+ T E P P + + T++L+ WQPP G V Y
Sbjct: 720 QGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP--PEDTQNGMVQEYKVW 777
Query: 954 DEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
G + + N D + + L P +RY ++ A+T G G
Sbjct: 778 CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 822
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 201 bits (511), Expect = 4e-51
Identities = 213/844 (25%), Positives = 339/844 (40%), Gaps = 87/844 (10%)
Query: 116 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 175
G RL E P E V V +GE L C P ++ + + +
Sbjct: 31 GNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETD 90
Query: 176 QDERVT---MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN 228
+D+ + + +G+L+F ++ + + Y+C A + + +++ + +
Sbjct: 91 KDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDD 150
Query: 229 SMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPADRVTYQN 287
F N + +VA G+P +LEC G P PTI W + +
Sbjct: 151 ----------FRQNPTDVVVAA-GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI 199
Query: 288 HNKTLQLLKVGEEDDGEYRCLAENSLGSA-RHAYYVTVEAAPYWLHKPQSHLYGPGETAR 346
L + + D G Y C+ N +G +TV P +L +P + + E
Sbjct: 200 RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVE 259
Query: 347 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 406
CQVQG PQP V W+ + + D K L + +D C A NR G
Sbjct: 260 FRCQVQGDPQPTVRWKKDDADLPRGRYDIK---DDYTLRIKKTMSTDEGTYMCIAENRVG 316
Query: 407 LLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-- 464
+ A+A + V P ++ +Q + QG T C+ G P P+V W E +L
Sbjct: 317 KMEASATLTVRAPPQFVVRPRDQ--IVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 374
Query: 465 -----QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ----- 514
+ R G L I ++Q +D G Y C A ++ A L+V D
Sbjct: 375 NQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPP 434
Query: 515 -ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 573
I QGP + C+A+ DP P I+W +G D E G L I
Sbjct: 435 IILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR-DPRATIQEQGTLQI 491
Query: 574 HSLDYSDQGNYSCVASTE---------LDVVESRAQLL----VVGSPGPVPRLVLSDLHL 620
+L SD G Y+CVA++ LDV ES A + + PGP + ++D+
Sbjct: 492 KNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDV-- 549
Query: 621 LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHY 680
T++ V +SW P P Y IE + ++ W ++ T L P Y
Sbjct: 550 -TKNSVTLSWQPGTPGTLPASAYIIEAFSQSVS-NSWQTVANHVKTTLYTVRGLRPNTIY 607
Query: 681 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI----------TW 730
F V AIN G +PSP+S+ V T + +P VD + E ++++ T
Sbjct: 608 LFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTT 667
Query: 731 KPLRWMDWNAPQV--QYRVQWRPQG---TRGPWQE---QIVSDPFLVVSNTSTFVPYEIK 782
+ W PQ YRV +R WQ ++ ++ V+ N V YEIK
Sbjct: 668 VQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIK 727
Query: 783 VQAVNSQGKGPEPQVTIGYSGEDYPQAIPE---LEGIEILNSSAVLVKWRPVDLAQVKGH 839
V+ ++ +G + + + E+ P A P+ + + NS+++ V W P G
Sbjct: 728 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGI 787
Query: 840 LRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG 899
++ Y + W G++ ++ HI+K V A SVI+ GL P Y +EV A G G
Sbjct: 788 IQEYKI--WCLGNE---TRFHINK---TVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Query: 900 PASE 903
SE
Sbjct: 840 VKSE 843
Score = 187 bits (476), Expect = 4e-47
Identities = 143/500 (28%), Positives = 228/500 (45%), Gaps = 37/500 (7%)
Query: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
PP I E P ++V + +L C+A G+P W +DG + ++ + SG
Sbjct: 46 PPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 89 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSH----EIRLMAEGAPKWPKETVKPVEV 143
S F + + ++ +G Y C A N LG A+S E+ L+ + + P + V V
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV----V 160
Query: 144 EEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYI 203
GE +L C PP IYW K+ ++ER+++ + G L +N SD
Sbjct: 161 AAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNTRKSDAGMYTC 219
Query: 204 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 263
+ G R +P +L V +R L P N V L+ + + C +G
Sbjct: 220 VGTNMVGER---DSDPAELTV------FERPTFLRRPINQ----VVLEEEAVEFRCQVQG 266
Query: 264 FPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 323
P PT++W + +P R ++ + TL++ K D+G Y C+AEN +G + +T
Sbjct: 267 DPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLT 325
Query: 324 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYR 378
V A P ++ +P+ + G T C+ +G PQP V W+ G P + + +
Sbjct: 326 VRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCS 385
Query: 379 IQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-----PAKILTADNQTYM 432
+ G L ++N+Q SD C+A G +LA A + V + P IL +
Sbjct: 386 VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTL 445
Query: 433 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 492
AV G TA L CKA G P+P + WL E T +D R GTL I++L+ +DTG Y C
Sbjct: 446 AVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 504
Query: 493 LAANDQNNVTIMANLKVKDA 512
+A + + A L V ++
Sbjct: 505 VATSSSGETSWSAVLDVTES 524
Score = 163 bits (412), Expect = 1e-39
Identities = 204/839 (24%), Positives = 339/839 (40%), Gaps = 116/839 (13%)
Query: 232 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 291
D PR++ S ++ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 44 DFPPRIV---EHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 100
Query: 292 LQ-----LLKV-----GEEDDGEYRCLAENSLGSA--RHAYYVTVEAAPYWLHKPQSHLY 339
L L++ + D+G Y C+A N LG A R+A + P +
Sbjct: 101 LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV 160
Query: 340 GPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQ 398
GE A L+CQ +G P+P + W+ + + +++ K+++ I+ G L++SN + SD +
Sbjct: 161 AAGEPAILECQPPRGHPEPTIYWKKDKVRIDD--KEERISIRGGKLMISNTRKSDAGMYT 218
Query: 399 CEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLD 457
C N G ++ A + V + P + NQ + ++ C+ G P P+V+W
Sbjct: 219 CVGTNMVGERDSDPAELTVFERPTFLRRPINQ--VVLEEEAVEFRCQVQGDPQPTVRWKK 276
Query: 458 EDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 517
+D L R+ + TL I+ + D G Y C+A N + A L V+ Q
Sbjct: 277 DDAD--LPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV 334
Query: 518 GPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGR------DLQELGDSDKYFIEDGRL 571
PR I +G VTF C+ +P QP++ W+ +G + + +S G L
Sbjct: 335 RPRDQIVAQGRTVTFPCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL 392
Query: 572 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS----------PGPVPRLVLSDLHLL 621
I ++ SD G Y C A T + ++AQL V GP + + D L
Sbjct: 393 TITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTAL 452
Query: 622 TQSQVR------VSWS------PAEDHNAPI-EKYDIEFEDKEMAPEKWYSLGKVPGNQT 668
+ + +SW P D A I E+ ++ ++ ++ Y+ +
Sbjct: 453 LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC---VATSS 509
Query: 669 STTLKLSPYVHYTFRVTAINKYG-----PGEPSPVSETVVTPEAAPEKNPVDVKGEGNET 723
S S + T I+K PG PS T VT KN V
Sbjct: 510 SGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVT------KNSV--------- 554
Query: 724 TNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI--VSDPFLVVSNTSTFVPYEI 781
++W+P P Y ++ Q WQ V V Y
Sbjct: 555 ---TLSWQP--GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLF 609
Query: 782 KVQAVNSQG-KGPEPQ--------VTIGYSGEDYPQAIPELEGI-------EILNSSAVL 825
V+A+N QG P P ++ G D+ Q EL + +L + V
Sbjct: 610 MVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQ 669
Query: 826 VKWRPVDLAQVKGHLRGYNVTYWR-EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYS 884
V W Q ++GY V Y + G Q S +++ VP ++V+++ L+
Sbjct: 670 VTWTVDRQPQF---IQGYRVMYRQTSGLQATSSWQNLDAK---VPTERSAVLVN-LKKGV 722
Query: 885 SYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPE----ALHLECQSNTSLLLRWQPPLSH 939
+Y ++V+ + G SE T T E P P L + ++TS+ + W PP
Sbjct: 723 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD 782
Query: 940 NGVLTGYVLSYHPLDEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 997
+ G + Y G + + N D +R+ + L P ++YR ++ A+T G G
Sbjct: 783 H--QNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,168,427
Number of Sequences: 37866
Number of extensions: 2740556
Number of successful extensions: 17132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 273
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 7313
Number of HSP's gapped (non-prelim): 4415
length of query: 1248
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1134
effective length of database: 13,930,794
effective search space: 15797520396
effective search space used: 15797520396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.