SYK 12992

Name: SYK	Sequence: fasta or formatted (635aa)		NCBI GI: 21361553
Description: spleen tyrosine kinase isoform 1		Referenced in: Non-Receptor Tyrosine Kinase Pathways
Other entries for this name: alt prot [612aa] spleen tyrosine kinase isoform 2
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.1 45 2 C cysteine 1.4 9 1 D aspartate 4.3 27 1 E glutamate 7.6 48 2 F phenylalanine 3.0 19 3 G glycine 7.9 50 2 H histidine 3.0 19 2 I isoleucine 4.1 26 2 K lysine 7.7 49 2 L leucine 9.4 60 2 M methionine 3.0 19 1 N asparagine 4.7 30 2 P proline 5.2 33 1 Q glutamine 4.4 28 2 R arginine 4.9 31 1 S serine 6.0 38 2 T threonine 3.6 23 2 V valine 5.7 36 2 W tryptophan 1.7 11 1 Y tyrosine 5.4 34 3			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 spleen tyrosine kinase isoform 1 SYK 0.952 spleen tyrosine kinase isoform 2 ZAP70 0.518 zeta-chain associated protein kinase 70kDa isoform 1... ZAP70 0.279 zeta-chain associated protein kinase 70kDa isoform 2... PTK2 0.146 PTK2 protein tyrosine kinase 2 isoform b PTK2 0.146 PTK2 protein tyrosine kinase 2 isoform a ABL1 0.141 c-abl oncogene 1, receptor tyrosine kinase isoform a... ABL1 0.141 c-abl oncogene 1, receptor tyrosine kinase isoform b... ERBB4 0.140 v-erb-a erythroblastic leukemia viral oncogene homo... ERBB4 0.140 v-erb-a erythroblastic leukemia viral oncogene homolo... ABL2 0.139 arg tyrosine kinase isoform c ABL2 0.139 arg tyrosine kinase isoform b ABL2 0.139 arg tyrosine kinase isoform e ABL2 0.139 arg tyrosine kinase isoform d ABL2 0.139 arg tyrosine kinase isoform a EGFR 0.139 epidermal growth factor receptor isoform a precursor... PTK2B 0.133 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... PTK2B 0.133 PTK2B protein tyrosine kinase 2 beta isoform b [Homo... PTK2B 0.133 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... PTK2B 0.133 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... FRK 0.132 fyn-related kinase LCK 0.131 lymphocyte-specific protein tyrosine kinase precurs... LCK 0.131 lymphocyte-specific protein tyrosine kinase precurs... EPHB1 0.130 ephrin receptor EphB1 precursor TNK2 0.129 tyrosine kinase, non-receptor, 2 isoform 1 TNK2 0.129 tyrosine kinase, non-receptor, 2 isoform 2 ERBB2 0.129 erbB-2 isoform b ERBB2 0.129 erbB-2 isoform a FER 0.129 fer (fps/fes related) tyrosine kinase FES 0.129 feline sarcoma oncogene isoform 4 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.