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Search of human proteins with 198442849
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198442849 transcription factor 7 (T-cell specific, HMG-box)
5 [Homo sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 769 0.0
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 568 e-162
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 513 e-145
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 511 e-145
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 509 e-144
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 509 e-144
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 509 e-144
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 316 2e-86
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 309 2e-84
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 307 1e-83
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 246 3e-65
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 244 9e-65
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 236 3e-62
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 233 2e-61
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 233 3e-61
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 230 2e-60
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 230 2e-60
gi|112421108 capicua homolog [Homo sapiens] 72 6e-13
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 65 7e-11
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 65 7e-11
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 65 7e-11
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 65 7e-11
gi|8924248 SRY-box 18 [Homo sapiens] 63 5e-10
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 61 1e-09
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 60 4e-09
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 60 4e-09
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 60 4e-09
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 60 4e-09
gi|41406089 SRY-box 13 [Homo sapiens] 57 3e-08
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 56 4e-08
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 770 bits (1987), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSP 300
STTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSP
Sbjct: 241 STTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSP 300
Query: 301 APQDSPSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGPPQAPRSTLQSTQVQQQE 360
APQDSPSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGPPQAPRSTLQSTQVQQQE
Sbjct: 301 APQDSPSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGPPQAPRSTLQSTQVQQQE 360
Query: 361 SQRQVA 366
SQRQVA
Sbjct: 361 SQRQVA 366
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 568 bits (1464), Expect = e-162
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STTDPGSPKKCRARFGLNQQTDWCGPCR 268
STTDPGSPKKCRARFGLNQQTDWCGPCR
Sbjct: 241 STTDPGSPKKCRARFGLNQQTDWCGPCR 268
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 513 bits (1320), Expect = e-145
Identities = 244/252 (96%), Positives = 248/252 (98%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STTDPGSPKKCR 252
STT+ P++ +
Sbjct: 241 STTETNWPRELK 252
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 511 bits (1317), Expect = e-145
Identities = 244/244 (100%), Positives = 244/244 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STTD 244
STTD
Sbjct: 241 STTD 244
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STT 243
STT
Sbjct: 241 STT 243
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
Query: 241 STT 243
STT
Sbjct: 356 STT 358
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 241 STT 243
STT
Sbjct: 241 STT 243
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 316 bits (809), Expect = 2e-86
Identities = 181/352 (51%), Positives = 213/352 (60%), Gaps = 52/352 (14%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 90 QLPHTVSW----------------FTHP---SLMLGSGVPG------------HPAAIPH 118
Q+PH + W F HP +L + + + H IPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 119 PAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
PAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 236 EKHQESTTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALG 295
+K T D +PKKCRARFGL+QQ +WCGPCRRKKKC+RY+ GEG C SP SD S L
Sbjct: 409 DKQPGETNDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLD 468
Query: 296 CPGSPAPQDSPSYHLLPRFPTELLTSPAEPAPTS----PGLSTALSLPTPGP 343
P PS +LL P + + + P S P LS+ P P
Sbjct: 469 SP-------PPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPP 513
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 309 bits (792), Expect = 2e-84
Identities = 179/352 (50%), Positives = 211/352 (59%), Gaps = 52/352 (14%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 192 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 251
Query: 90 QLPHTVSW----------------FTHP---SLMLGSGVPG------------HPAAIPH 118
Q+PH + W F HP +L + + + H IPH
Sbjct: 252 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 311
Query: 119 PAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
PAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AE
Sbjct: 312 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 371
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R
Sbjct: 372 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 431
Query: 236 EKHQESTTDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALG 295
+K T D +PKKCRA FGL++QT WC PCRRKKKC+RY+ GEG C SP SD S L
Sbjct: 432 DKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLD 491
Query: 296 CPGSPAPQDSPSYHLLPRFPTELLTSPAEPAPTS----PGLSTALSLPTPGP 343
P PS +LL P + + + P S P LS+ P P
Sbjct: 492 SP-------PPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPP 536
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 307 bits (786), Expect = 1e-83
Identities = 182/369 (49%), Positives = 214/369 (57%), Gaps = 69/369 (18%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 90 QLPHTVSW----------------FTHP---SLMLGSGVPG------------HPAAIPH 118
Q+PH + W F HP +L + + + H IPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 119 PAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
PAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 236 EKHQEST-----------------TDPGSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLP 278
+K T TD +PKKCRARFGL+QQ +WCGPCRRKKKC+RY+
Sbjct: 409 DKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQ 468
Query: 279 GEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAEPAPTS----PGLST 334
GEG C SP SD S L P PS +LL P + + + P S P
Sbjct: 469 GEGSCLSPPSSDGSLLDSP-------PPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLA 521
Query: 335 ALSLPTPGP 343
LS+ P P
Sbjct: 522 HLSMMPPPP 530
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 246 bits (627), Expect = 3e-65
Identities = 134/221 (60%), Positives = 155/221 (70%), Gaps = 14/221 (6%)
Query: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Query: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
Query: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPG 246
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES + G
Sbjct: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTG 363
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 244 bits (623), Expect = 9e-65
Identities = 133/218 (61%), Positives = 154/218 (70%), Gaps = 14/218 (6%)
Query: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Query: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
Query: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTT 243
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +
Sbjct: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 236 bits (601), Expect = 3e-62
Identities = 155/375 (41%), Positives = 193/375 (51%), Gaps = 78/375 (20%)
Query: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
Query: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
Query: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
Query: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
Query: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCG 265
LARKERQLH QLYP WSARDNYGKKK+R REK T Q+ +
Sbjct: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQV----------QEAEGAL 447
Query: 266 PCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAEP 325
+ KK C++YLP E C SP S S L P + P+ L SPA P
Sbjct: 448 ASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPAT---------------PSAALASPAAP 492
Query: 326 APTSPGLSTALSLPT 340
A T + LSL T
Sbjct: 493 AATHSEQAQPLSLTT 507
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 233 bits (594), Expect = 2e-61
Identities = 133/246 (54%), Positives = 154/246 (62%), Gaps = 36/246 (14%)
Query: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Query: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Q+ + W P + G +PG H IPHPAIV
Sbjct: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Query: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
Query: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
Query: 241 STTDPG 246
S + G
Sbjct: 386 SASGTG 391
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 233 bits (593), Expect = 3e-61
Identities = 131/245 (53%), Positives = 152/245 (62%), Gaps = 37/245 (15%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 90 QLPHTVSWFTHPSLMLGSGVPGHP---------------------------AAIPHPAIV 122
Q+PH + W P + +G HP IPHPAIV
Sbjct: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Query: 123 PPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLK 179
P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLK
Sbjct: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
Query: 180 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQ 239
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K
Sbjct: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
Query: 240 ESTTD 244
T +
Sbjct: 409 GETNE 413
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 230 bits (586), Expect = 2e-60
Identities = 132/247 (53%), Positives = 154/247 (62%), Gaps = 41/247 (16%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 90 QLPHTVSW----------------FTHP---SLMLGSGVPG------------HPAAIPH 118
Q+PH + W F HP +L + + + H IPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 119 PAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
PAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 236 EKHQEST 242
+K T
Sbjct: 409 DKQPGET 415
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 230 bits (586), Expect = 2e-60
Identities = 132/247 (53%), Positives = 154/247 (62%), Gaps = 41/247 (16%)
Query: 37 QPPHGVPQLSLY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Q PH V L+ EHF +P P PAD+ K + RP PD+S +Y L+ G++G
Sbjct: 216 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 275
Query: 90 QLPHTVSW----------------FTHP---SLMLGSGVPG------------HPAAIPH 118
Q+PH + W F HP +L + + + H IPH
Sbjct: 276 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 335
Query: 119 PAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
PAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AE
Sbjct: 336 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 395
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R
Sbjct: 396 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 455
Query: 236 EKHQEST 242
+K T
Sbjct: 456 DKQPGET 462
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 72.4 bits (176), Expect = 6e-13
Identities = 64/259 (24%), Positives = 112/259 (43%), Gaps = 39/259 (15%)
Query: 3 KETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQ--LSLYEHFNSPHPTPAP 60
KE SA + H PP G G +PP + P P L + E P PT
Sbjct: 72 KEPAESA--AVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPT--- 126
Query: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
++++ P P L S + H ++ + S P
Sbjct: 127 ---TEEEASGPPGEPRLD--------SETESDHDDAFLSIMS--------------PEIQ 161
Query: 121 IVPPSGKQELQ-----PFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAE 175
+ P GK+ Q P +R+ ++ + ++ + +K I++P+NAFM++ K RA V
Sbjct: 162 LPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQR 221
Query: 176 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR 235
+++ +++ILG W+AL +E+ KY++LA + ++ H + +P W + +K+ S
Sbjct: 222 HPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNK--DRKKSSS 279
Query: 236 EKHQESTTDPGSPKKCRAR 254
E S G K+ R R
Sbjct: 280 EAKPTSLGLAGGHKETRER 298
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 284 PSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGP 343
P+P P+ + P PAP S + L P T A APT PG+ S+P+ P
Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVL-AATAPT-PGIPILQSVPSAPP 897
Query: 344 PQA 346
P+A
Sbjct: 898 PKA 900
Score = 33.1 bits (74), Expect = 0.40
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 7/92 (7%)
Query: 277 LPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLL----PRFPTELLTSPAEPAPTSPGL 332
LPG+ P PS G G P P SP + + + P++++ P T GL
Sbjct: 918 LPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGL 977
Query: 333 STALSLPT-PGPPQAPRSTL--QSTQVQQQES 361
LS T PGP P+ L ST++ +S
Sbjct: 978 VPPLSPATLPGPTSQPQKVLLPSSTRITYVQS 1009
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 30/210 (14%)
Query: 139 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 193
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 614 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 673
Query: 194 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRA 253
++S +E+ YYE + ++H++ YP NY K R R + +
Sbjct: 674 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKRTCIVDGK---------KL 718
Query: 254 RFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGS-PAPQDSPSYHLLP 312
R G +Q R +++ +R G+ P + + + PG+ +PS P
Sbjct: 719 RIGEYKQL-----MRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPS----P 769
Query: 313 RFPTELLTSPAEPAPTSPGLSTALSLPTPG 342
+ ++ ++ A P P+ P + + + T G
Sbjct: 770 QMTSDCSSTSASPEPSLPVIQSTYGMKTDG 799
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 30/210 (14%)
Query: 139 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 193
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 574 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 633
Query: 194 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRA 253
++S +E+ YYE + ++H++ YP NY K R R + +
Sbjct: 634 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKRTCIVDGK---------KL 678
Query: 254 RFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGS-PAPQDSPSYHLLP 312
R G +Q R +++ +R G+ P + + + PG+ +PS P
Sbjct: 679 RIGEYKQL-----MRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPS----P 729
Query: 313 RFPTELLTSPAEPAPTSPGLSTALSLPTPG 342
+ ++ ++ A P P+ P + + + T G
Sbjct: 730 QMTSDCSSTSASPEPSLPVIQSTYGMKTDG 759
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 30/210 (14%)
Query: 139 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 193
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 577 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 636
Query: 194 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRA 253
++S +E+ YYE + ++H++ YP NY K R R + +
Sbjct: 637 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKRTCIVDGK---------KL 681
Query: 254 RFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGS-PAPQDSPSYHLLP 312
R G +Q R +++ +R G+ P + + + PG+ +PS P
Sbjct: 682 RIGEYKQL-----MRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPS----P 732
Query: 313 RFPTELLTSPAEPAPTSPGLSTALSLPTPG 342
+ ++ ++ A P P+ P + + + T G
Sbjct: 733 QMTSDCSSTSASPEPSLPVIQSTYGMKTDG 762
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 30/210 (14%)
Query: 139 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 193
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 581 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 640
Query: 194 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRA 253
++S +E+ YYE + ++H++ YP NY K R R + +
Sbjct: 641 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKRTCIVDGK---------KL 685
Query: 254 RFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGS-PAPQDSPSYHLLP 312
R G +Q R +++ +R G+ P + + + PG+ +PS P
Sbjct: 686 RIGEYKQL-----MRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPS----P 736
Query: 313 RFPTELLTSPAEPAPTSPGLSTALSLPTPG 342
+ ++ ++ A P P+ P + + + T G
Sbjct: 737 QMTSDCSSTSASPEPSLPVIQSTYGMKTDG 766
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 62.8 bits (151), Expect = 5e-10
Identities = 71/273 (26%), Positives = 109/273 (39%), Gaps = 52/273 (19%)
Query: 110 PGHPAAIPHPAIVPPS----GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYM 165
P PA+ P P PP G+ L P R E +A E++ I++P+NAFM++
Sbjct: 45 PAAPASPPSPQRSPPRSPEPGRYGLSPAGRG-----ERQAADESR---IRRPMNAFMVWA 96
Query: 166 KEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 225
K+ R ++ + +A ++++LG+ W L+ E+ + E A + R H++ +P + R
Sbjct: 97 KDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRP 156
Query: 226 NYGKKKRRSREKH----------QESTTDP-----GSPKKCRARFGLNQQTDWCGPCRRK 270
K+ R++R + +P GS + R L + D G
Sbjct: 157 RRKKQARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPPLGAEFDGLG----- 211
Query: 271 KKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHL-LPRFPTELLTSP--AEPAP 327
LP R P A P AP+D P PTEL P AP
Sbjct: 212 ------LPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAP 265
Query: 328 TSPGLSTAL-----------SLPTPGPPQAPRS 349
+ L TA +L TPGP P S
Sbjct: 266 LAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLS 298
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/235 (24%), Positives = 99/235 (42%), Gaps = 24/235 (10%)
Query: 109 VPGHPAAIPHPAIVPPSGKQELQ-------PFDRNLKTQAESKAEKEAKKPTIKKPLNAF 161
VP P +++ PS K E + P D + SK + +K+P+NAF
Sbjct: 289 VPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKD----RNGHVKRPMNAF 344
Query: 162 MLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 221
M++ + R + +A I+ LG W+ LS E++ YY+ A+K ++ H + +PGW
Sbjct: 345 MVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGW 404
Query: 222 SARDNYGKKKR--------RSREKHQESTTDPGSPKKCRA-RFGL---NQQTDWCGPCRR 269
+ GK+KR S +T+P + R+ + + + Q P
Sbjct: 405 VYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGE 464
Query: 270 KKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAE 324
I+ + PSPV ++ A QD PS + P P + T P++
Sbjct: 465 TSPAIQLPTPAVQSPSPVTLFQPSVSSAAQVAVQD-PSLPVYPALPPQRFTGPSQ 518
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 30/208 (14%)
Query: 141 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 195
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 152 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 211
Query: 196 SREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARF 255
+ E+ YYE + + H++ YP +Y K R R T KK R
Sbjct: 212 TNLEKQPYYEEQARLSKQHLEKYP------DYKYKPRPKR-------TCLVDGKKLRI-- 256
Query: 256 GLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFP 315
++ R +++ +R G+ + +P + + PG+ A PS HL P
Sbjct: 257 -----GEYKAIMRNRRQEMRQYFNVGQ-QAQIPIATAGVVYPGAIAMAGMPSPHL----P 306
Query: 316 TELLTSPAEPAPTSPGLSTALSLPTPGP 343
+E + + P P P + + + P
Sbjct: 307 SEHSSVSSSPEPGMPVIQSTYGVKGEEP 334
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 30/208 (14%)
Query: 141 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 195
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 525 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 584
Query: 196 SREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARF 255
+ E+ YYE + + H++ YP +Y K R R T KK R
Sbjct: 585 TNLEKQPYYEEQARLSKQHLEKYP------DYKYKPRPKR-------TCLVDGKKLRI-- 629
Query: 256 GLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFP 315
++ R +++ +R G+ + +P + + PG+ A PS HL P
Sbjct: 630 -----GEYKAIMRNRRQEMRQYFNVGQ-QAQIPIATAGVVYPGAIAMAGMPSPHL----P 679
Query: 316 TELLTSPAEPAPTSPGLSTALSLPTPGP 343
+E + + P P P + + + P
Sbjct: 680 SEHSSVSSSPEPGMPVIQSTYGVKGEEP 707
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 30/208 (14%)
Query: 141 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 195
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 538 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 597
Query: 196 SREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARF 255
+ E+ YYE + + H++ YP +Y K R R T KK R
Sbjct: 598 TNLEKQPYYEEQARLSKQHLEKYP------DYKYKPRPKR-------TCLVDGKKLRI-- 642
Query: 256 GLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFP 315
++ R +++ +R G+ + +P + + PG+ A PS HL P
Sbjct: 643 -----GEYKAIMRNRRQEMRQYFNVGQ-QAQIPIATAGVVYPGAIAMAGMPSPHL----P 692
Query: 316 TELLTSPAEPAPTSPGLSTALSLPTPGP 343
+E + + P P P + + + P
Sbjct: 693 SEHSSVSSSPEPGMPVIQSTYGVKGEEP 720
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 59.7 bits (143), Expect = 4e-09
Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 11/131 (8%)
Query: 109 VPGHPAAIPHPAIVPPSGKQELQ-------PFDRNLKTQAESKAEKEAKKPTIKKPLNAF 161
VP P +++ PS K E + P D + SK + +K+P+NAF
Sbjct: 289 VPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKD----RNGHVKRPMNAF 344
Query: 162 MLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 221
M++ + R + +A I+ LG W+ LS E++ YY+ A+K ++ H + +PGW
Sbjct: 345 MVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGW 404
Query: 222 SARDNYGKKKR 232
+ GK+KR
Sbjct: 405 VYQPRPGKRKR 415
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 56.6 bits (135), Expect = 3e-08
Identities = 23/68 (33%), Positives = 45/68 (66%)
Query: 154 IKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQL 213
IK+P+NAFM++ K+ R K++ +++I++ILG RW +++ +E+ YYE + +
Sbjct: 424 IKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQ 483
Query: 214 HMQLYPGW 221
H++ YP +
Sbjct: 484 HLEKYPDY 491
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/115 (26%), Positives = 56/115 (48%)
Query: 124 PSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAA 183
P G Q+ T A + ++ +K+P+NAFM++ + R K+ E ++
Sbjct: 11 PPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 70
Query: 184 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKH 238
I++ LG W LS E+ + + A++ R LHM+ +P + R K ++K+
Sbjct: 71 ISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 125
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,850,929
Number of Sequences: 37866
Number of extensions: 1332105
Number of successful extensions: 9862
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 7178
Number of HSP's gapped (non-prelim): 2931
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.