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Search of human proteins with 194440727
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo
sapiens]
(3092 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 6259 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 2092 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1868 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 1497 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1276 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 1145 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 1093 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 976 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 969 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 965 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 954 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 954 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 924 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 916 0.0
gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] 898 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 717 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 690 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 605 e-172
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 435 e-121
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 162 5e-39
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 55 1e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 9e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 9e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 8e-05
gi|219803769 trichoplein [Homo sapiens] 49 8e-05
gi|14150056 trichoplein [Homo sapiens] 49 8e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 1e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 1e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 1e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 48 2e-04
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 6259 bits (16237), Expect = 0.0
Identities = 3092/3092 (100%), Positives = 3092/3092 (100%)
Query: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG
Sbjct: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
Query: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML
Sbjct: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
Query: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP
Sbjct: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
Query: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID
Sbjct: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
Query: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL
Sbjct: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
Query: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA
Sbjct: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
Query: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW
Sbjct: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
Query: 421 LLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGL 480
LLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGL
Sbjct: 421 LLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGL 480
Query: 481 TNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTV 540
TNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTV
Sbjct: 481 TNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTV 540
Query: 541 GIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK 600
GIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK
Sbjct: 541 GIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK 600
Query: 601 KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFIN 660
KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFIN
Sbjct: 601 KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFIN 660
Query: 661 KEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADV 720
KEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADV
Sbjct: 661 KEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADV 720
Query: 721 EEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWK 780
EEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWK
Sbjct: 721 EEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWK 780
Query: 781 QISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDI 840
QISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDI
Sbjct: 781 QISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDI 840
Query: 841 AFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQE 900
AFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQE
Sbjct: 841 AFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQE 900
Query: 901 TIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATS 960
TIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATS
Sbjct: 901 TIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATS 960
Query: 961 LTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPH 1020
LTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPH
Sbjct: 961 LTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPH 1020
Query: 1021 LKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSV 1080
LKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSV
Sbjct: 1021 LKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSV 1080
Query: 1081 HDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQN 1140
HDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQN
Sbjct: 1081 HDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQN 1140
Query: 1141 QLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWE 1200
QLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWE
Sbjct: 1141 QLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWE 1200
Query: 1201 NENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKT 1260
NENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKT
Sbjct: 1201 NENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKT 1260
Query: 1261 ETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQ 1320
ETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQ
Sbjct: 1261 ETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQ 1320
Query: 1321 QILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMV 1380
QILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMV
Sbjct: 1321 QILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMV 1380
Query: 1381 PNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL 1440
PNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL
Sbjct: 1381 PNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL 1440
Query: 1441 KLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHE 1500
KLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHE
Sbjct: 1441 KLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHE 1500
Query: 1501 ACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYG 1560
ACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYG
Sbjct: 1501 ACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYG 1560
Query: 1561 EEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPI 1620
EEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPI
Sbjct: 1561 EEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPI 1620
Query: 1621 DTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPS 1680
DTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPS
Sbjct: 1621 DTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPS 1680
Query: 1681 QLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNYLYTTIVSKI 1740
QLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNYLYTTIVSKI
Sbjct: 1681 QLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNYLYTTIVSKI 1740
Query: 1741 LKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIR 1800
LKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIR
Sbjct: 1741 LKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIR 1800
Query: 1801 LIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIK 1860
LIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIK
Sbjct: 1801 LIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIK 1860
Query: 1861 IQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYI 1920
IQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYI
Sbjct: 1861 IQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYI 1920
Query: 1921 NLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLR 1980
NLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLR
Sbjct: 1921 NLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLR 1980
Query: 1981 QFFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMV 2040
QFFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMV
Sbjct: 1981 QFFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMV 2040
Query: 2041 RIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100
RIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR
Sbjct: 2041 RIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100
Query: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF 2160
VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF
Sbjct: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF 2160
Query: 2161 HSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYN 2220
HSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYN
Sbjct: 2161 HSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYN 2220
Query: 2221 QTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQ 2280
QTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQ
Sbjct: 2221 QTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQ 2280
Query: 2281 PEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLF 2340
PEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLF
Sbjct: 2281 PEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLF 2340
Query: 2341 EKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRA 2400
EKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRA
Sbjct: 2341 EKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRA 2400
Query: 2401 SEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKIT 2460
SEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKIT
Sbjct: 2401 SEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKIT 2460
Query: 2461 PAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMS 2520
PAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMS
Sbjct: 2461 PAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMS 2520
Query: 2521 GNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNS 2580
GNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNS
Sbjct: 2521 GNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNS 2580
Query: 2581 SFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKEL 2640
SFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKEL
Sbjct: 2581 SFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKEL 2640
Query: 2641 AWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAI 2700
AWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAI
Sbjct: 2641 AWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAI 2700
Query: 2701 SYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYI 2760
SYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYI
Sbjct: 2701 SYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYI 2760
Query: 2761 EFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEI 2820
EFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEI
Sbjct: 2761 EFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEI 2820
Query: 2821 TKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKG 2880
TKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKG
Sbjct: 2821 TKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKG 2880
Query: 2881 VVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCV 2940
VVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCV
Sbjct: 2881 VVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCV 2940
Query: 2941 FWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDG 3000
FWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDG
Sbjct: 2941 FWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDG 3000
Query: 3001 ARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGH 3060
ARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGH
Sbjct: 3001 ARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGH 3060
Query: 3061 STNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 3092
STNFVIAMLLKTDQPTRHWIKRGVALLCQLDD
Sbjct: 3061 STNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 3092
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 2092 bits (5421), Expect = 0.0
Identities = 1096/2238 (48%), Positives = 1484/2238 (66%), Gaps = 57/2238 (2%)
Query: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Y Y+ +++ + P++ WL+H+L L+P+ LK + + +L +E+ D+ S+++
Sbjct: 165 YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221
Query: 156 LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214
+V VL P K + + LP ++ PW S++ A + I +L+ ++PTM +
Sbjct: 222 IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281
Query: 215 LDLGYTTFADTVLLDFTGIR-AKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271
LDL +T F L+D + ++ S + + +A+E ++ W+P+V N++
Sbjct: 282 LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341
Query: 272 --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325
KK+ G KL++F++C + LM+ QL+DL +++ F L P D R P
Sbjct: 342 GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401
Query: 326 FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385
F + L D+D ++F P D D L++ + + +A+ V + + L + T L
Sbjct: 402 FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461
Query: 386 EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441
+L+ VD +K + + +H Y +KY++L+ A +++ F E+H+++
Sbjct: 462 PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520
Query: 442 EYTEFIEKFLSLASEIMLLP-QWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYR 500
+ + I K+ L EI + I M + CE+L L +A LL + ++
Sbjct: 521 KIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQ 580
Query: 501 KENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL 560
+ N +C EFE I E AL P T E+M++ +Y++K + EL R+ +SK +++ +
Sbjct: 581 EVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLI 640
Query: 561 DVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKES 620
+ F D+ LN +V W ++ IF+E+ ++I+ + + L + E+ + E+E +
Sbjct: 641 EYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYA 700
Query: 621 RRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLK 680
++ EEF F +L+ +Q+Y+ + L ++ + + ++ N EEE F W + YP+ K++
Sbjct: 701 KQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQ 760
Query: 681 VNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKK 740
+ PY + + +++ + + W +G + +N + +EAD+ + R ++K L+K
Sbjct: 761 DGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYK--------LEK 812
Query: 741 ELQEKRKAARKRSLEEEKIEEEPKDNATI-TMCR--MRARHWKQISEIVGYDLTPDSGTT 797
+ A K+E+ + I +C +R RHW+ +S IVGY L P +T
Sbjct: 813 TFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDST 872
Query: 798 LRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSS 857
+ L +NL PY+++FE IS ASKE+SLEKAM MI W+ + F I YR+TG IL+S
Sbjct: 873 VSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILAS 932
Query: 858 VDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEP 917
VDEIQ +LDD IIKTQTMRGSPFIKP+E +++ WE +L+ +QE +DEWLKVQA WLYLEP
Sbjct: 933 VDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEP 992
Query: 918 IFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEK 977
IF S DIM QMPEEGR+F VD+ WRDIM+ +D VL ++ +LE+L+ NELLE
Sbjct: 993 IFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLEL 1052
Query: 978 IMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNL 1037
I+KGLN YLEKKRLFFPRFFFLSNDE+LEILSETKDP RVQPHLKKCFEGIAK+EF L
Sbjct: 1053 ILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETL 1112
Query: 1038 DIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARR 1097
DI M SSEGE VELI +IST+ ARG VEKWL+++E +M+ S+H V A AY + R
Sbjct: 1113 DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERI 1172
Query: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQT 1157
+WVR+WPGQ VLC+SQ+FWT E Q I G + L++Y K Q+++IV LVRGKLS Q
Sbjct: 1173 NWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN 1232
Query: 1158 RTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVKYAY 1217
R TLGALV +DVHARDV+ ++K +S D+DF WL+QLRYYW+ + ++IN ++Y Y
Sbjct: 1233 RVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLRYGY 1292
Query: 1218 EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVF 1277
EYLGNSPRLVITPLTDRCYRTL GA +L+LGGAPEGPAGTGKTETTKDLAKA+A QCVVF
Sbjct: 1293 EYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVF 1352
Query: 1278 NCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFV 1337
NCSDGLDYLA+GKFFKGL S GAWACFDEFNRI+LEVLSVVAQQIL IQR I + +
Sbjct: 1353 NCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILM 1412
Query: 1338 FEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFL 1397
FEGTELKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMVP+YA+IAEI LYS GF+
Sbjct: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472
Query: 1398 NARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSI 1457
ARPLSVKIV TYRLCSEQLSSQ HYDYGMRAVK+VL AAGNLKLKYPNENE+ILLLRSI
Sbjct: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSI 1532
Query: 1458 KDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKI 1517
DVN PKFLSHD+PLF GITSDLFPG+KLP+ DY++ L + C NLQ FF EKI
Sbjct: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKI 1592
Query: 1518 IQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITM 1577
+Q YEMMIVRHGFM+VGEPF KT VLA L + E G EE KV +NPKS+TM
Sbjct: 1593 LQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTM 1652
Query: 1578 GQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKK 1637
GQL+GQFD VSHEW+DG++A +FR FA S TPDRKW++FDGP+D +WIE+MNTVLDDNKK
Sbjct: 1653 GQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKK 1712
Query: 1638 LCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKG 1697
LCLMSGEIIQMSPQM+LIFE MDL ASPATVSRCGMIY+EP LGW PL+ SW+N L
Sbjct: 1713 LCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPA 1772
Query: 1698 PLCEPEYQALLRGLFAWLIPPSLN-QRVELFQLNYLYTTIVSKILKILITFRISNYFKYV 1756
+ + + ++ GLF ++P S+ R +L+ T + + L LI + ++ V
Sbjct: 1773 SVSVIQKEFIM-GLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEV 1831
Query: 1757 PLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPD-- 1814
LK + + L + F+FSLIWS+G SC D R F+ +R ++ E+P+ D
Sbjct: 1832 KLKERNDRETYSL-LEGIFLFSLIWSVGASCTDDDRLKFNKILRELM-----ESPISDRT 1885
Query: 1815 -------------SVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKI 1861
S PF EKG +YDY + + G+W W + +K K +
Sbjct: 1886 RNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMF 1945
Query: 1862 QDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYIN 1921
+IIVPT+DTIRY+ LM+L T+ KP +FVGPTGTGKSVY+ + L+N L K+ Y P IN
Sbjct: 1946 NEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLIN 2005
Query: 1922 LSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQ 1981
SA+T+A Q QNI+M++LDKRRKGVFGPP+GK+ ++F+DD+NMPA E YGAQPPIELLRQ
Sbjct: 2006 FSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQ 2065
Query: 1982 FFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVR 2041
+ D +WYDLKD S I LVDI+++ AMGPPGGGRNPVTPR +RHFNI +IN FSD++M
Sbjct: 2066 WLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYT 2125
Query: 2042 IFSSIVAFYLR-THEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100
IFS I+ ++L ++FP E+ + QIVNGTM +YK++++NLLPTP KSHY FNLRDFSR
Sbjct: 2126 IFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSR 2185
Query: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF 2160
VI+G L + + RL+VHEVLRV+YDRL+++ DR WL + +++++ E F
Sbjct: 2186 VIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDF 2245
Query: 2161 HSIFSHLRKQNAPVTE-EDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEY 2219
H +F L N + E +DLR+LMF D+ +P E D Y EI ++ + +V+ L+EY
Sbjct: 2246 HELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRE--DTNYREIADVDNLRMIVEIHLEEY 2303
Query: 2220 NQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIF 2279
N K MNLV+FR+ +EH+SRI R+LKQ +ALLVG+GGSGRQS+TRLA MA +F
Sbjct: 2304 NNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVF 2363
Query: 2280 QPEISKSYGMNEWREDMK 2297
Q EISK Y EW ED+K
Sbjct: 2364 QVEISKGYDTTEWHEDLK 2381
Score = 1006 bits (2602), Expect = 0.0
Identities = 472/780 (60%), Positives = 603/780 (77%), Gaps = 3/780 (0%)
Query: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
KS+IL KRL+ L DHFTY+LY N+CRSLFEKDKLLFSF L NLLL + I E FLL
Sbjct: 3247 KSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLL 3306
Query: 2372 TGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHN 2431
TGG+ L + N TWL KSW+EICR + PAF+ +R+ F W+++YDS EPH+
Sbjct: 3307 TGGIGLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHH 3365
Query: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSN 2491
FP + NE Q+++I+RCLRPDK+ P + ++ ++LG+ F+EPPPFDL K++ DSN
Sbjct: 3366 EVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSN 3425
Query: 2492 CTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWV 2551
C PLIFVLSPGADPMA+LLKFA+D+ G+K ++SLGQGQGPIA KM++ A++EGTWV
Sbjct: 3426 CCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWV 3485
Query: 2552 CLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPT 2611
LQNCHLA SWMP LEK+CE+ + E+ + FR+WLTSYPS FPV++LQNGVKMTNE P
Sbjct: 3486 VLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPK 3545
Query: 2612 GLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPY 2671
GLR N+++SYL DP+SDPEFF C+ E ++KLL+G+CFFHALVQER+KFGPLGWNIPY
Sbjct: 3546 GLRANIIRSYLMDPISDPEFFGSCKKPE-EFKKLLYGLCFFHALVQERRKFGPLGWNIPY 3604
Query: 2672 GFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYN 2731
FNE+DLRIS++QL +F+N+Y+ +P+EA+ Y+TGECNYGGRVTDDWDRR L ++L F+N
Sbjct: 3605 EFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFN 3664
Query: 2732 LYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTK 2791
+VEN YKF SG YF PP G ++ YIE+ K LP T PEIFG++ N DI+KD +T+
Sbjct: 3665 PELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQ 3724
Query: 2792 TLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNT 2851
LF+++LLTQ S GA S+D+++ E+ DIL KLP++FDIE A+R+YP Y +SMNT
Sbjct: 3725 LLFDNILLTQSRSAGAGAK-SSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNT 3783
Query: 2852 VLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPS 2911
VLVQEM RFN L+ TIR++ +++KAIKG+ VM + LE + S+L K+PE+W +SYPS
Sbjct: 3784 VLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPS 3843
Query: 2912 LKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLL 2971
LKPLGSY+ DFLARL FLQ WY G P VFWLSGFFFTQAFLTGA QNYARKYT PIDLL
Sbjct: 3844 LKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLL 3903
Query: 2972 GYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQ 3031
G+++EV+ PEDGV+IHGL+LDGA W+R+ LAE +PK+L+D +P++W+KP +
Sbjct: 3904 GFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCK 3963
Query: 3032 KSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLD 3091
++ I K +YV PLYKTSER+G LSTTGHSTNFVIAM L +DQP HWI RGVALLCQL+
Sbjct: 3964 RADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLN 4023
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1868 bits (4838), Expect = 0.0
Identities = 1025/2281 (44%), Positives = 1405/2281 (61%), Gaps = 114/2281 (4%)
Query: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155
Y Y+ + + P + E + + +LI +L E L+ L+ E +D+ S+ +
Sbjct: 235 YYYLTNGIRKDMIAPEEGEVMVRISKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKS 294
Query: 156 LVQSVLVKPPVKS---LEDEGGPLPESPVGLDYSNPWHSSYVQARNQIFSNLHIIHPTMK 212
+V +L+ P + +E P+ + PWHS Y A+ +LH ++P M
Sbjct: 295 IVDYILMDPMERKRLFIESIPRLFPQRVIRAPV--PWHSVYRSAKKWNEEHLHTVNPMML 352
Query: 213 MLLDLGYTTFADTVLLDFTGIRA-KGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF 271
L +L + F D + I A K P+ + + A + ++N W P LF
Sbjct: 353 RLKELWFAEFRDLRFVRTAEILAGKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLF 412
Query: 272 T-KKEALEGVKPEK-------LDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-------- 315
T +KE P+ ++ +++ V++ MS QL++L+ +++E V LF
Sbjct: 413 TSRKEHWIHFAPKSNYDSSRNIEEYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGND 472
Query: 316 --DPKDQQRL---PIFKIELTFDDDKMEFYPTFQD----LEDNVLSLVERIAEALQNVQT 366
+P + + + I+L + + F P+F + D+ L +++ + + ++
Sbjct: 473 FKEPYQEMKFFIPQLIMIKLEVSEPIIVFNPSFDGCWELIRDSFLEIIKN-SNGIPKLKY 531
Query: 367 IPSWLSGTSTPVNLDT-------ELPEHVLHWAVDTLKA--------------------- 398
IP S T+ + E H A+ LK
Sbjct: 532 IPLKFSFTAAAADRQCVKAAEPGEPSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQ 591
Query: 399 ---AVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLAS 455
+N G K+ Y +KY LLD TA +NI F E+H D++ I +
Sbjct: 592 TFKVFQKNQVGPCKYLNVY-KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRN 650
Query: 456 EIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIKE 515
EI + + M LD L L +A+ + L+ R N IC+++ I +
Sbjct: 651 EIASMNITVPLAMFCLDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIAD 710
Query: 516 HALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNAT 575
+VP T+E++ LI +++K+ V + +L +++++ ++ + +D DL
Sbjct: 711 KVSEVPANTKELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDY-----ADL----- 760
Query: 576 VLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFT--EFAELE 633
P +I IFD + L+ + + + E +L+ + + L +E R +E F E E
Sbjct: 761 ----PYQIEDIFDNSRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTE 816
Query: 634 RMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFV 693
M+ V + +L K + + + INKEEEL + E + YP L + N PY++ ++
Sbjct: 817 EMKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTA 876
Query: 694 LKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRS 753
++ + WM+G LN E + ++ R +K +K ++ R+ A
Sbjct: 877 YEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLS-----DVPAPRRLAENVK 931
Query: 754 LEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQF 813
++ +K ++ + M+ RHW+QISEIVGY++ P T L +L+ ++E+
Sbjct: 932 IKIDKFKQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVEKL 991
Query: 814 EVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQ 873
E I A ASKE+SLEK ++ M W ++ F YRDT IL ++D+IQ +LDD +IKTQ
Sbjct: 992 EPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQ 1051
Query: 874 TMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGR 933
TM GSPFIKP E E + WE++LIRIQ+ +D WLK QA WLYLEPIF SEDI+ QMPEEGR
Sbjct: 1052 TMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGR 1111
Query: 934 QFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFF 993
+F VD +W+ +M KD ++L A + EKLQ N LLE I KGLN YLEKKRLFF
Sbjct: 1112 KFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFF 1171
Query: 994 PRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIKAMYSSEGERVELI 1053
PRFFFLSNDE+LEILSETKDPLRVQPHLKKCFEGIAKLEF NL+I M SSE E V I
Sbjct: 1172 PRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEIVGMISSEKETVPFI 1231
Query: 1054 ALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQ 1113
I + A+G VEKWL QVE +ML S+ +VI AY + R WV +WPGQVV+C+S
Sbjct: 1232 QKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSS 1291
Query: 1114 MFWTSETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARD 1173
+FWT E + ++ T L + K+ +Q+ +IV+LVRGKLS R TLGAL IDVHARD
Sbjct: 1292 IFWTQEVSQALAENT--LLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARD 1349
Query: 1174 VVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVKYAYEYLGNSPRLVITPLTD 1233
VV + + VS DF W++QLRYYW ++ +V+II Y YEYLGNSPRLVITPLTD
Sbjct: 1350 VVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQIITTEALYGYEYLGNSPRLVITPLTD 1409
Query: 1234 RCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFK 1293
RCYRTL+GA LNLGGAPEGPAGTGKTETTKDLAKALA QCVVFNCSDGLDY AMGKFFK
Sbjct: 1410 RCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFK 1469
Query: 1294 GLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAI 1353
GLA +GAWACFDEFNRIE+EVLSVVAQQIL IQ+AI +KL F+FEGTEL LNP C V I
Sbjct: 1470 GLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFI 1529
Query: 1354 TMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLC 1413
TMNPGYAGR+ELPDNLK LFRTVAMMVP+YALI EISLYS GFL++R L+ KIV TYRLC
Sbjct: 1530 TMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLC 1589
Query: 1414 SEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLF 1473
SEQLSSQ HYDYGMRAVK+VL AAGNLKLKYP ENE +LLLR++ DVN KFL+ D+PLF
Sbjct: 1590 SEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLF 1649
Query: 1474 NGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLV 1533
GI SDLFPG+ LP+ DY FL+ ++ LQPV +F+ KIIQ YEMM+VRHG+M+V
Sbjct: 1650 QGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIV 1709
Query: 1534 GEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTD 1593
G+P KT VLA L ++ EE V Y+ +NPK+ITMGQL+G FD VSHEW D
Sbjct: 1710 GDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMD 1769
Query: 1594 GIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMS 1653
G++AN FRE A S + DRKW++FDGP+D +WIE+MNTVLDDNKKLCLMSGEIIQM+ +MS
Sbjct: 1770 GVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMS 1829
Query: 1654 LIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFA 1713
LIFE DL QASPATVSRCGMIY+EP QLGW+PL S++++L L + E++ L+ +F
Sbjct: 1830 LIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTK-EHKELVNDMFM 1888
Query: 1714 WLIPPSLNQRVELFQLNYLYTTIVSKILKILITFRISNYF------------KYVPLKTQ 1761
WL+ P L + L+ V + I + F + + + + L
Sbjct: 1889 WLVQPCL-------EFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEG 1941
Query: 1762 CTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWEC 1821
+ + FL Q F+FSL+W++ G+ + D R+ FD F R +I+G DD +P P SV +
Sbjct: 1942 LSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKN 2001
Query: 1822 P-FDEKGLVYDYMYELKNKGRWVHWNELI-KNTNLGDKQIKIQDIIVPTMDTIRYTFLMD 1879
F E+G +YD+ + + G W W + I K K+ ++I+PTM+T R +F +
Sbjct: 2002 NIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLK 2061
Query: 1880 LSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARL 1939
+ + P+LFVGPTGTGKS + L+ HL K+ Y P IN SARTSANQ Q+IIM++L
Sbjct: 2062 TYLDHEIPMLFVGPTGTGKSAITNNFLL-HLPKNTYLPNCINFSARTSANQTQDIIMSKL 2120
Query: 1940 DKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITL 1999
D+RRKG+FGPP+GKK ++F+DD+NMPA E YGAQPPIELLRQ+ D G+W+D KDT+++ +
Sbjct: 2121 DRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDI 2180
Query: 2000 VDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPE 2059
VD+ L+ AMGPPGGGRN +T R RH NI SIN+F D+ + +IFSSIV ++ F
Sbjct: 2181 VDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF-GKGFDVM 2239
Query: 2060 YFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTM 2119
+ G +V T IY+ +VEN LPTP+KSHY FNLRDFSRVI+G LL + +
Sbjct: 2240 FLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKC 2299
Query: 2120 IRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDL 2179
IRL++HEV RVFYDRLI+ +DR+ F + K + FK++ + HL + ++++
Sbjct: 2300 IRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHL-SPTGKIVDDNI 2358
Query: 2180 RNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHL 2239
R+L FGDY P E D ++Y EI ++ + V++ L+E+N K M+LV+FR+ +EH+
Sbjct: 2359 RSLFFGDYFKP--ESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHI 2416
Query: 2240 SRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSF 2299
SRICRVLKQ G+ LLVG+GGSGRQS +L+T M ++Q EI+K+Y N+WRED+K
Sbjct: 2417 SRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKI 2476
Query: 2300 I 2300
I
Sbjct: 2477 I 2477
Score = 972 bits (2512), Expect = 0.0
Identities = 463/784 (59%), Positives = 593/784 (75%), Gaps = 8/784 (1%)
Query: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
KS+ L R++Y+ DHFT ++Y N+CRSLFEKDKLLFS LL ++ +KEI + FLL
Sbjct: 3338 KSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLL 3397
Query: 2372 TGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHN 2431
TGG++L + NP P WL +K+W EI RAS P GL +H +++ EW+ IYDS PH
Sbjct: 3398 TGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHE 3457
Query: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSN 2491
+ P K L+K++ILRCLRPDK+ PA+ ++ + +GK ++E P FDL SY DS+
Sbjct: 3458 EQLPGSW-KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSS 3516
Query: 2492 CTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWV 2551
C PLIFVLSP ADPMA LLKFA+D M G + Q ISLGQGQGPIAAKMI AI++GTWV
Sbjct: 3517 CCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWV 3576
Query: 2552 CLQNCHLAVSWMPMLEKICED-FTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPP 2610
LQNCHLA SWMP LEKICE+ E+ N+ FRLWLTSYPS KFPV+ILQNG+KMTNEPP
Sbjct: 3577 VLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPP 3636
Query: 2611 TGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIP 2670
GLR NLL+SYL DP+SDP FF+ C K + W+K+LFG+CFFHA+VQER+ FGPLGWNIP
Sbjct: 3637 KGLRANLLRSYLNDPISDPVFFQSC-AKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIP 3695
Query: 2671 YGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFY 2730
Y FNESDLRIS+ Q+Q+F+N+Y +PF+A++YLTGECNYGGRVTDD DRRLLL++L+ FY
Sbjct: 3696 YEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFY 3755
Query: 2731 NLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQT 2790
I E+ +Y +P Y+ PP G+Y+ YI++++ LP T HPE+FGLHEN DI+KD Q+T
Sbjct: 3756 CKEIEED-YYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQET 3814
Query: 2791 KTLFESLLLTQGGSKQTGASGSTDQ-ILLEITKDILNKLPSDFDIEMALRKYPVRYEESM 2849
LFE +LLT +Q+G SG + Q ++ E+ +DIL+KLP DFD+E ++ YPV YEESM
Sbjct: 3815 NQLFEGVLLTL--PRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESM 3872
Query: 2850 NTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSY 2909
NTVL QE+ RFN L +R +L +L +AIKG V+M S LE + S+LVGKVP +WA +SY
Sbjct: 3873 NTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSY 3932
Query: 2910 PSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPID 2969
PSLKPLG Y+ D LARL F Q+W + G P VFW+SGF+FTQ+FLTG QNYARKYT PID
Sbjct: 3933 PSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPID 3992
Query: 2970 LLGYEFEVIPSDT-SDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIK 3028
+G+EFEV P +T + +PEDG YI GL+L+GARWDR++ + E PK+L+D +PIIW+K
Sbjct: 3993 HIGFEFEVTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLK 4052
Query: 3029 PTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLC 3088
P + + + D YVCP+YKTS R+GTLSTTGHSTN+V+++ L TD P +HWI RGVA LC
Sbjct: 4053 PGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLC 4112
Query: 3089 QLDD 3092
QLD+
Sbjct: 4113 QLDN 4116
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 1497 bits (3876), Expect = 0.0
Identities = 915/2330 (39%), Positives = 1304/2330 (55%), Gaps = 207/2330 (8%)
Query: 127 LKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPP-----VKSLEDEGGPLPESPV 181
+++G E L SL EVS D+E SM + V+ P V + E +PE +
Sbjct: 424 MRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGL 483
Query: 182 GLDYSNPWHSSYVQARNQIFSNL----HIIHPTMKMLLDLGYTTFADTV---------LL 228
S P + + Q + F +L +I K+ + T L
Sbjct: 484 ---VSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE 540
Query: 229 DFTGIRAKGPIDCESLKTD-----LSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPE 283
+F I+++ + D L + R++ + WY NL+ E
Sbjct: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWY----NLYETN--WEVYLMS 594
Query: 284 KLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFD----------------------PKDQQ 321
KL V ++ + L+ L++ ++ F + P +
Sbjct: 595 KLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPR 654
Query: 322 RLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPS------WLSGTS 375
+ P+F ++L D + + + E ++L+L ++ A V + ++SG
Sbjct: 655 KNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGD- 713
Query: 376 TPVNLDTELPEHVLHWAVDTLKAAVHRN---LEGARKHYETYVEKYNWLLDGTAVENIET 432
P+ L E ++ T+ +AV + L+ K Y Y+E N ++T
Sbjct: 714 -PLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNN----NDIASFLKT 768
Query: 433 FQTEDHTFDEYTEFIEKFL--------SLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKA 484
+QT+ E E + L SL S I++ P +I+ +++K L+ K
Sbjct: 769 YQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYIN-------TDNVKQSLSKKR 821
Query: 485 KAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVE--KARTVGI 542
KA A +L+ +A KE + IC EF +I + P + EE+ +L +++ R VG+
Sbjct: 822 KALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGL 881
Query: 543 EELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFD-------ENDELIE 595
EE I+++ + + M FL + +D WP KI + E++E
Sbjct: 882 EERIVKVMDDYQVMDEFL--YNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFR 939
Query: 596 NAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEA 655
+ +N K E L L + F+ E+ R + +VR+++K++++ ++
Sbjct: 940 KIQIMDQNNFQEKLEGLQLVVAG-------FSIHVEISRAHEIANEVRRVKKQLKDCQQL 992
Query: 656 VQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGES 715
N E +F +T Y +L ++ +PY + W R + WM+ ++ E
Sbjct: 993 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ 1052
Query: 716 MEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR-- 773
+E +V E + + K +K F K QE R R IEE I R
Sbjct: 1053 LEKNVVEAFKTMHKCVKQF--KDMPACQEVALDIRAR------IEEFKPYIPLIQGLRNP 1104
Query: 774 -MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNT 832
MR RHW+ +S + ++ P + T + L++NL ++E ++ A KE+++E+A++
Sbjct: 1105 GMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDK 1164
Query: 833 MIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWE 892
M W I F++ Y+ T IL S DE +LDD I+ TQ M SP+ KPFE I +WE
Sbjct: 1165 MEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWE 1224
Query: 893 DRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKD 952
++L QE ++EWL Q WLYLEPIF SEDI QQ+P E +++QT++R W+ IMK ++
Sbjct: 1225 NKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYEN 1284
Query: 953 PKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETK 1012
+V+ S +L+ L++CN++L+ + KGL+ YLE KR FPRF+FLS+DE+LEILS+TK
Sbjct: 1285 REVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTK 1344
Query: 1013 DPLRVQPHLKKCFEGIAKLEFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQV 1072
DP VQPHL+KCFE IA+L F +L+I MYS+EGE V+L I S+ VE WL +V
Sbjct: 1345 DPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSN---VEDWLREV 1401
Query: 1073 EDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGTEGLK 1132
E M SVHD+I A AYP R WV WPGQV + Q +WT E E + G
Sbjct: 1402 ERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLR-S 1460
Query: 1133 KYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWL 1192
+ + +L QL+++V LVRGKLS+ R L AL+ I+VHA+DVV +I+ V DF W+
Sbjct: 1461 QLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWI 1520
Query: 1193 AQLRYYWENENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPE 1252
+QLRYYW N + +R +N Y YEYLGNS RLVITPLTDRCY TL GA +L GGAP
Sbjct: 1521 SQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPA 1580
Query: 1253 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 1312
GPAGTGKTETTKDL KALA+Q VVFNCSD LD++AMGKFFKGLAS+GAWACFDEFNRI++
Sbjct: 1581 GPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDI 1640
Query: 1313 EVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVL 1372
EVLSVVAQQI IQ+A QQ++ F+FEG E+ L P+C V ITMNPGYAGR+ELPDNLK L
Sbjct: 1641 EVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKAL 1700
Query: 1373 FRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKA 1432
FR VAMMVP+YA+I EISLYS+GF A L+ KI T++L SEQLSSQ HYD+GMRAVK
Sbjct: 1701 FRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKT 1760
Query: 1433 VLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYH 1492
V+ AAGNLK + P+ NE+++ LR+I+DVN PKFL D+ LF+GI SDLFP IK + DY
Sbjct: 1761 VISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYG 1820
Query: 1493 EFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLT 1552
E EAC NL+ V+ FL K IQ YE +VRHG MLVG + K+ VLA +T
Sbjct: 1821 ILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMT 1880
Query: 1553 LMNEH---GYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETP 1609
+ G E V Y +NPKSITMGQL+G+FD ++HEWTDGI ++ R A++
Sbjct: 1881 SLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDT 1940
Query: 1610 DRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATV 1669
++KW +FDGP+D +WIE+MNTVLDDNKKLCL SGEII+++ M+++FE DL+ ASPATV
Sbjct: 1941 NKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATV 2000
Query: 1670 SRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSL-----NQRV 1724
SRCGM+YLEPS LG P + WL L PL +P Y+ + LF + S+ + +
Sbjct: 2001 SRCGMVYLEPSILGLMPFIECWLRKLP-PLLKP-YEEHFKALFVSFLEESISFVRSSVKE 2058
Query: 1725 ELFQLNYLYTTIVSKILKILI-TFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSI 1783
+ N T + K+L F K +P + ++ + FIFSLIWS+
Sbjct: 2059 VIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELI---EPWFIFSLIWSV 2115
Query: 1784 GGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMY--------- 1834
G + D+ GR F ++RL + EN + F E+GLV+DY
Sbjct: 2116 GATGDSSGRTSFSHWLRLKM-----ENE------QLTLLFPEEGLVFDYRLEDAGISGTN 2164
Query: 1835 ------ELKNKGRWVHWNE------LIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSI 1882
E + WV W + ++ +TN +IIVPTMDT++ + L+D+ +
Sbjct: 2165 DSEDEEEEYKQVAWVKWMDSSAPFTMVPDTN-------YCNIIVPTMDTVQMSHLLDMLL 2217
Query: 1883 TYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKR 1942
T KP+L +GPTGTGK++ + DKL+ +L D Y ++ SARTSANQ Q+ I ++LDKR
Sbjct: 2218 TNKKPVLCIGPTGTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKR 2276
Query: 1943 RKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKI-TLVD 2001
RKGVFGPP+G+ I FIDD+NMPALE YGAQPPIELLRQ+ D G WYD K LVD
Sbjct: 2277 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD 2336
Query: 2002 IELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYL--------RT 2053
I + AMGPPGGGRN VTPR +RHFN S + + RIFS+I+ +L
Sbjct: 2337 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR 2396
Query: 2054 HEFP--PEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERD 2111
P P +V T+ +Y LLPTP KSHYTFNLRD S+V +G L+ +
Sbjct: 2397 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA 2456
Query: 2112 AVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQN 2171
V ++ ++RL+ HE RVF DRL+N++DR W QL K + + ++ +F+ +
Sbjct: 2457 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCM-EQWEVTFNKVC------- 2508
Query: 2172 APVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVI 2231
+ +++GD+M+P D + Y I + V+++ +++YNQ + ++ LV+
Sbjct: 2509 ------PFQPILYGDFMSPG--SDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVL 2560
Query: 2232 FRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNE 2291
F + H+ RI R L+Q+ GNALL+G+GGSGR SLTRLA+ MA+ FQ E+SK+YGM+E
Sbjct: 2561 FMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSE 2620
Query: 2292 WREDMKSFIA------VPVTNRIVDNKSK---ILEKRLRYLNDHFTYNLY 2332
WR+D+K + +P+T D + K LE LN NLY
Sbjct: 2621 WRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLY 2670
Score = 780 bits (2014), Expect = 0.0
Identities = 388/780 (49%), Positives = 525/780 (67%), Gaps = 13/780 (1%)
Query: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
L+KR+ +N + TY+LY N+CRSLFEK KL+F+FLLC +++ +I E +LL+GG
Sbjct: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGG- 3552
Query: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
S+ +NP P WL D++W +I S P F F +H+ E+R I+DS EPH P
Sbjct: 3553 SISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
Query: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
D+ L++ QK+++LRCLR DK+T A+ ++V L +F+EP +L+ + DSN T P
Sbjct: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
Query: 2496 LIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCLQN 2555
LIFVLSPG DP A L KFA + S K AISLGQGQGP A M++++IE G WV QN
Sbjct: 3673 LIFVLSPGTDPAADLYKFAEEMKFS-KKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQN 3731
Query: 2556 CHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGLRL 2615
CHLA SWMP LE++ E + + FRLWLTS PS+KFPV+ILQNG KMT EPP G+R
Sbjct: 3732 CHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRA 3791
Query: 2616 NLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNE 2675
NLL+SY + +F C K + ++ LL +C FH ER+KFGPLG+NIPY F +
Sbjct: 3792 NLLKSYSS---LGEDFLNSCH-KVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTD 3847
Query: 2676 SDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIV 2735
DLRI I QL++F++EYD IP++ + Y GE NYGGRVTDDWDRR ++ +L DFYN ++
Sbjct: 3848 GDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVL 3907
Query: 2736 ENPHYKFSPSGNYFA-PPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLF 2794
+P + +S SG Y PP Y+ +IK LP PEIFGLH+N +I+ +T L
Sbjct: 3908 -SPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALL 3966
Query: 2795 ESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLV 2854
+++ Q S G+ G ++I+ ++T++IL K+P +++ + KYPV YEESMNTVLV
Sbjct: 3967 GTIIQLQPKSSSAGSQGR-EEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLV 4025
Query: 2855 QEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKP 2914
QE+ R+N L+ I TL+DL KA+KG+VVM S LE ++ SL VPE+W+ ++YPSLKP
Sbjct: 4026 QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKP 4085
Query: 2915 LGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYE 2974
L S++ D L RL+FLQ W G P VFW+SGFFF QAFLTG +QN+ARK+ ID + ++
Sbjct: 4086 LSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFD 4145
Query: 2975 FEVI---PSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQ 3031
F+V+ PS+ + P+ G YIHGL+L+GARWD E+ LAE PK L+ M +IW+ PT
Sbjct: 4146 FKVMFEAPSELTQ-RPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTP 4204
Query: 3032 KSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLD 3091
+ D Y+CP+YKT R GTLSTTGHSTN+VIA+ + T QP RHWIKRGVAL+C LD
Sbjct: 4205 NRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALD 4264
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 1276 bits (3301), Expect = 0.0
Identities = 776/2107 (36%), Positives = 1174/2107 (55%), Gaps = 154/2107 (7%)
Query: 318 KDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTI--PSWLSGTS 375
+D+ +P+F EL + F P+ +D D +L V + +V + S+ +
Sbjct: 505 EDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFT 564
Query: 376 TP-VNLDTE--------------LPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
+P +N E + H + +K + E AR + T+ EK+
Sbjct: 565 SPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATF-EKFQI 623
Query: 421 LLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGL 480
+++ + ++ + ++E +EK+ + + L + ++ +D L+ L
Sbjct: 624 FFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKL 683
Query: 481 TNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTV 540
+L + + +K+ + I E + + VP TT E + + ++++
Sbjct: 684 IPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDE---- 739
Query: 541 GIEELILRIQESKR---QMSYFLDVFLFPQ--EDLALNATVLMWPRKINPIFDENDELIE 595
I+E I +++ QM ++ + P ED A+ AT M P + +
Sbjct: 740 -IQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFAT--MKPSIV---------AVR 787
Query: 596 NAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEA 655
NA K + + ++ + + + + +L+ + D+ Q +I+
Sbjct: 788 NAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNN 847
Query: 656 VQFINKE-----------EELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWM 704
+Q + + ++ FK E++K+ L+++ ++ Q ++ +W + ++ W+
Sbjct: 848 LQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWL 907
Query: 705 DGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPK 764
F L+ E + V ++++ F T+L+K L + + + EK++E+
Sbjct: 908 KSKFDCLDPEVLNGQVSKYAK--------FVTQLEKGLPPNSVVPQLK-YKVEKMKEKLP 958
Query: 765 DNATITMCRMRARHWKQISEIVGYDLTP-DSGTTLRKVLKLNLTPYLEQFEVISAGASKE 823
+ ++ARHW I + V L + TL ++ +L++ + ++ + IS AS E
Sbjct: 959 VIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGE 1018
Query: 824 FSLEKAMNTMIGTWEDIAFHISLYRDT-GVCILSSVDEIQAILDDQIIKTQTMRGSPFIK 882
+LE + + +W+ F I +RD+ V IL D+IQ +LDD I T+ S ++
Sbjct: 1019 AALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLG 1078
Query: 883 PFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHW 942
P + + W+ +L +T++EWL Q WLYLE IF + DI +Q+P E + F VD+ W
Sbjct: 1079 PLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSW 1138
Query: 943 RDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSND 1002
++IM+ + P L A + GLLE QN N LL++I K L AYLE KR+ FPRF+FLSND
Sbjct: 1139 KEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSND 1198
Query: 1003 EMLEILSETKDPLRVQPHLKKCFEGIAKLEF---------LPNLD----------IKAMY 1043
E+LEIL++T++P VQPHL+KCF+ I+KLEF +P +D I AM
Sbjct: 1199 ELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAML 1258
Query: 1044 SSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWV-RE 1102
S EGERV L + ARG VE+WL +VE+ M S+ + AA Y R DWV
Sbjct: 1259 SPEGERVSLGKGLK---ARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAG 1315
Query: 1103 WPGQVVLCISQMFWTSETQEVI----SGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTR 1158
P QV+L +SQ+ W + E + S + LK + K +LN + +V+G L K R
Sbjct: 1316 HPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHR 1375
Query: 1159 TTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYA 1216
L AL+TIDVHARD+V ++++ V F W QLRYYW+ + N R+ Y
Sbjct: 1376 NILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYG 1435
Query: 1217 YEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVV 1276
YEYLG PRLVITPLTDRCY L+GA L+LGGAP GPAGTGKTETTKDLAKALA+QCVV
Sbjct: 1436 YEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVV 1495
Query: 1277 FNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVF 1336
FNCSDGLDY MG+FF GLA SGAW CFDEFNRI++EVLSV+AQQ++ I+ A KL F
Sbjct: 1496 FNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRF 1555
Query: 1337 VFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGF 1396
+FEG E+KL C ITMNPGYAGR+ELPDNLK LFR AMMVPNYALIAE+ LYS GF
Sbjct: 1556 MFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGF 1615
Query: 1397 LNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRS 1456
+++ L+ K+ Y+LCSEQLS Q HYD+GMRAVK+VLV AG+LK + P+ NED++L+R+
Sbjct: 1616 ESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRA 1675
Query: 1457 IKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEK 1516
++D N PKFL+ D LF+GI SDLFPG+++PE DY + N NLQP + K
Sbjct: 1676 LQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRK 1735
Query: 1517 IIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTV-----N 1571
+IQ YE M+VRHG MLVG KT V +LA+TL + + G E Y+ V N
Sbjct: 1736 VIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGI---ENSFYQAVKTYVLN 1792
Query: 1572 PKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTV 1631
PKSITMG+L+G+ + ++ EW DG++A + R + D KW++ DGP+D LWIE+MNTV
Sbjct: 1793 PKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTV 1852
Query: 1632 LDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSW 1691
LDDNK LCL + E I+++PQ+ ++FE DL ASPATVSRCGM++++P +L W P V +W
Sbjct: 1853 LDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTW 1912
Query: 1692 LNSLKGPLCEPEYQALLRGLFAWLIPPSL---NQRVE--LFQLNYLYTTIVSKILKILIT 1746
+ + L E E Q + LF + L N++ + Q++ T + +L+ LI
Sbjct: 1913 MKGISKKLTE-ETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLIL 1971
Query: 1747 FRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGK 1806
+ V L + T + L Q F+F +WS+GG+ + FDTFIR +
Sbjct: 1972 GKDG-----VNLAMEQTKLNTILCQ--TFVFCYLWSLGGNLTENYYDSFDTFIRT----Q 2020
Query: 1807 DDENP---VPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQD 1863
D+NP +P+S W D ++ K W E I T ++ + +
Sbjct: 2021 FDDNPDARLPNSGDLWSIHMD---------FDTKRLDPW----ERIIPTFKYNRDVPFFE 2067
Query: 1864 IIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLS 1923
++VPT DT+RY +LM+ + +LF G TG GKSV K L E Y P Y+N S
Sbjct: 2068 MLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFS 2127
Query: 1924 ARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFF 1983
A+TS+ + Q II ++L+++RK + G P K+ +IF+DD+NMP L++YG+QPPIELLRQ+
Sbjct: 2128 AQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQ 2187
Query: 1984 DCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIF 2043
D G +YD + D+ +I+A PPGGGRNPVTPR IRHF++ + S+ ++ +IF
Sbjct: 2188 DFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIF 2247
Query: 2044 SSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIR 2103
+I+ +L +FPP + IV ++EIY + +LLPTP KSHY FNLRD S+ ++
Sbjct: 2248 QAILNGFL--SDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQ 2305
Query: 2104 GCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSI 2163
G L + + + + RLF HE RVF+DRLIN++D+ + + + HF +
Sbjct: 2306 GILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLE 2365
Query: 2164 FSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTH 2223
+ N P+ +FGD++ + DR+Y ++P+I ++V+ LD+YN T+
Sbjct: 2366 YF----LNKPI--------IFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTN 2413
Query: 2224 KTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEI 2283
+ LV F+ +EH+SRI R+++Q GNALLVG+GG+G+QSLTRLA + Q E+
Sbjct: 2414 PKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIEL 2473
Query: 2284 SKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRS----- 2338
S+ Y + + ED++ + + D L + + + F ++ NI S
Sbjct: 2474 SRGYNYDSFHEDLRKLYKMA---GVEDKNMVFLFTDTQIVVEEFLEDIN-NILNSGEVPN 2529
Query: 2339 LFEKDKL 2345
LFEKD+L
Sbjct: 2530 LFEKDEL 2536
Score = 636 bits (1641), Expect = 0.0
Identities = 345/882 (39%), Positives = 509/882 (57%), Gaps = 63/882 (7%)
Query: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRY 2322
R+ +AT + M+ +S+ M ++ +K F + T K++ L++RL
Sbjct: 3288 REKYRPVATQGSVMYFVIASLSEIDPMYQY--SLKYFKQLFNTTIETSVKTENLQQRLDV 3345
Query: 2323 LNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSL-KSAE 2381
L + Y N+ R LFE+ KL++SF+LC ++ + + E F L G L K
Sbjct: 3346 LLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERP 3405
Query: 2382 KNPDPTWLQDKSWEEICRASE-FPAFRGLRQHFCEHIYEWR------------------- 2421
P+ WL +W C E FP F GL Q+ H R
Sbjct: 3406 PKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKM 3465
Query: 2422 --EIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPP 2479
E ++ A P L+ K+I+++C + +K+ A+T++V + LGK+F+E P
Sbjct: 3466 KHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETP 3525
Query: 2480 PFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAK 2539
P DL Y D +C PL+F+LS G+DPM + +FA + S + Q+ISLGQGQGPIA K
Sbjct: 3526 PVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYS-ERVQSISLGQGQGPIAEK 3584
Query: 2540 MIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTS--ETCNSSFRLWLTSYPSSKFPVT 2597
M+K A++ G WV LQNCHLAVSWM +E++ + FT +FRL+L+S PS+ FPVT
Sbjct: 3585 MVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVT 3644
Query: 2598 ILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFK-GCRGKELAWEKLLFGVCFFHALV 2656
+LQN VK+TNEPP GLR N+ +++ P FF+ GK+ W +++FG+CFFHA++
Sbjct: 3645 VLQNSVKVTNEPPKGLRANIRRAFTE---MTPSFFEENILGKK--WRQIIFGICFFHAII 3699
Query: 2657 QERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDD 2716
QERKKFGPLGWNI Y FN+SD ++ L+L+ E IP++A+ Y+TGE YGGRVTD
Sbjct: 3700 QERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDS 3758
Query: 2717 WDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFG 2776
WD+R L T+L F++ +E YK+S SG YFAP + +++ ++I+ LP PEIFG
Sbjct: 3759 WDQRCLRTILKRFFSPETLEED-YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFG 3817
Query: 2777 LHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEM 2836
+HEN ++ ++T TL ++L Q S G S D+I+ E+ + ++P ++E
Sbjct: 3818 MHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEG 3877
Query: 2837 ALRKYPVRYEE----SMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALS 2892
A V+ + S+ TVL QE++RFNNL+ I +L L KAI G VVM +E +
Sbjct: 3878 ASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVY 3937
Query: 2893 GSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAF 2952
S L +VP +W+ +YPSLKPLGS++ D + R +F+ W G+P +W+SGFFF Q F
Sbjct: 3938 NSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGF 3997
Query: 2953 LTGAMQNYARKYTTPIDLLGYEFEVIPS----------------------DTSDTSPEDG 2990
LTG +QN+ARKY PID L +++ VIP+ D SPEDG
Sbjct: 3998 LTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDG 4057
Query: 2991 VYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSE 3050
V +HG+++D +RWD + ++ + P + ++P++ +P Q + Y CPLYKT
Sbjct: 4058 VLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGA 4116
Query: 3051 RKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 3092
R GTLSTTGHSTNFV+ +LL + + +WI +G ALLCQL +
Sbjct: 4117 RAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQLSE 4158
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 1145 bits (2963), Expect = 0.0
Identities = 722/2022 (35%), Positives = 1079/2022 (53%), Gaps = 128/2022 (6%)
Query: 321 QRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTST---P 377
Q L I K +L ++EF PT Q L V + + + +P L+ P
Sbjct: 864 QVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRKLHREP 923
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTED 437
+ E E + + T ++ N ++Y + Y + + I +Q +
Sbjct: 924 IQTVVEQDEDIKK--IQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLN 981
Query: 438 HTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFAN---ILLND 494
+ I ++ +A+ + + V LDC LK L + N LL +
Sbjct: 982 PPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLRE 1041
Query: 495 IASKYRKENECICSEFEAIKEHALKV---PETTEEMMDLISYVE--KARTVGIEELILRI 549
+A+ E +KE+A K+ P+T EE+ + V+ K +E I I
Sbjct: 1042 MAAGRLLELHTY------LKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPI 1095
Query: 550 QESKRQMSYFLDVFLFPQEDLALNATVLM---WPRKINPIFDENDELIENAKHKKE---- 602
E L+ + P ED L + W + D L KHK++
Sbjct: 1096 HEQFA----ILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML---KKHKEKFKTG 1148
Query: 603 -----NELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQ 657
++ K L+ + E + + L++ +T VR + ++E E +++
Sbjct: 1149 LIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQ----ITQVRAMLMAMREEENSLR 1204
Query: 658 FINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESME 717
+FK E +L L+ ++ Q+ + W+ + W G FL L E+ME
Sbjct: 1205 ---ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETME 1261
Query: 718 ADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR---M 774
R + TKL KE +++ + + KIE+ + I+ R +
Sbjct: 1262 TTAHGLFRRL--------TKLAKEYKDRNWEIIETT--RSKIEQFKRTMPLISDLRNPAL 1311
Query: 775 RARHWKQISEIVGYDLTPDSGT-TLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
R RHW Q+ + + + +S + TL ++++L + ++E+ ISA A+KE ++E A+ +
Sbjct: 1312 RERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNI 1371
Query: 834 IGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWED 893
TW+ I Y+D G L +E+ L+D + TM+ S F+K FE ++ WE
Sbjct: 1372 AKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWER 1431
Query: 894 RLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDP 953
L I E I+ L VQ QW+YLE IF EDI +Q+P E F V+ +W+ IM KD
Sbjct: 1432 CLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDN 1491
Query: 954 KVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKD 1013
L +T GLL+ L N +LE I K L+ YLE KR FPRF+FLSND++LEIL ++++
Sbjct: 1492 NALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRN 1551
Query: 1014 PLRVQPHLKKCFEGIAKLEFLP------NLDIKAMYSSEGERVELIALISTSAARGAVEK 1067
P VQPHLKKCF+ I L + M+S +GE ++ + + G VE
Sbjct: 1552 PEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLE---GPVES 1608
Query: 1068 WLIQVEDLMLRSVHDVIAAARLAYPE--SARRDWVREWPGQVVLCISQMFWTSETQEVIS 1125
WL VE M ++ D++ LA + + R WV+EW GQVV+ SQ+ WT++ + +
Sbjct: 1609 WLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLL 1668
Query: 1126 GGTEG-----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIK 1180
E LK K + LN+ E +RG L+K R + ALVTI++HARDV+ + K
Sbjct: 1669 TAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYK 1728
Query: 1181 MGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRT 1238
G+ F WL+QLR+YWE + + +R N +Y YEYLGNS RLVITPLTDRCY T
Sbjct: 1729 SGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMT 1788
Query: 1239 LIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASS 1298
L A +L+ GG+P+GPAGTGKTET KDL KAL + +V NCS+GLDY +MG+ + GLA +
Sbjct: 1789 LTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQT 1848
Query: 1299 GAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPG 1358
GAW CFDEFNRI +EVLSVVA QILCI A+ L F F+G E+ L +C + ITMNPG
Sbjct: 1849 GAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPG 1908
Query: 1359 YAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLS 1418
YAGR+ELP+NLK +FR +AM+VP+ LIAEI L+ GF N + L+ K+ Y L +QLS
Sbjct: 1909 YAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLS 1968
Query: 1419 SQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITS 1478
Q HYD+G+RA+ ++L AG + P+ ++ +LL S++D+N K S D PLFN I
Sbjct: 1969 RQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQ 2028
Query: 1479 DLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFA 1538
DLFP I+LP DY + E + LQ F L K+ Q YE RH M+VG +
Sbjct: 2029 DLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGS 2088
Query: 1539 AKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVAN 1598
KT +L +L+ + G V +NPK++++G+L+G++D ++EWTDGI+++
Sbjct: 2089 GKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSS 2148
Query: 1599 TFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFET 1658
R E PD KW++FDGP+DTLWIE+MN+V+DDNK L L++GE I M Q+SL+FE
Sbjct: 2149 VMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEV 2208
Query: 1659 MDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPE-YQALLRGLFAWLIP 1717
DL+ ASPATVSRCGM+Y + + LGW+P V SWL K P E E Q + L ++
Sbjct: 2209 EDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLE--KRPKAEVEPLQRMFEKLINKMLA 2266
Query: 1718 PSLNQRVELFQL-NYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFI 1776
+ EL L Y T + K+ L T N + T + + F+
Sbjct: 2267 FKKDNCKELVPLPEYSGITSLCKLYSALAT--PENGVNPADGENYVTMV------EMTFV 2318
Query: 1777 FSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYEL 1836
FS+IWS+ S D +GR+ D+++R I E F K VY+Y +
Sbjct: 2319 FSMIWSVCASVDEEGRKRIDSYLREI-----------------EGSFPNKDTVYEYFVDP 2361
Query: 1837 KNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGT 1896
K + W + + + + I+VPT+DT+RY +L+ + P+L VGP GT
Sbjct: 2362 KIRS-WTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGT 2420
Query: 1897 GKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCI 1956
GK+ + ++ L Q+ +N+SA+T++N VQ+II +R++KR KGV+ P GK I
Sbjct: 2421 GKT-SIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMI 2479
Query: 1957 IFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRN 2016
F+DD+NMPA + +G+QPP+EL+R + D G WYD + + ++ L+AAMGPPGGGR
Sbjct: 2480 TFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRT 2539
Query: 2017 PVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYK 2076
++PR FNI ++ + ++RIF +++ L+ +F E IGN + T+++Y
Sbjct: 2540 VISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQ--DFEEEVKPIGNVVTEATLDMYN 2597
Query: 2077 QSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLI 2136
V+ LPTPTK HY FNLRD S+V +G L +D K ++ RL++HE RVF DRL+
Sbjct: 2598 TVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLV 2657
Query: 2137 NDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDD 2196
+ D + +I D F F HL P +FGD++ +
Sbjct: 2658 DAADT----EAFMGIISDKLGSFFDLTFHHLCPSKRPP--------IFGDFLK-----EP 2700
Query: 2197 RVYIEIPNIHHFSDVVDQCLDEYNQTHK-TRMNLVIFRYVLEHLSRICRVLKQSGGNALL 2255
+VY ++ ++ V++ L+EYN + M LV+FR +EH++RI RV+ Q GN LL
Sbjct: 2701 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL 2760
Query: 2256 VGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMK 2297
VG+GGSGRQSL RLA+S+ FQ E++K Y E+R+D+K
Sbjct: 2761 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIK 2802
Score = 597 bits (1538), Expect = e-170
Identities = 319/803 (39%), Positives = 471/803 (58%), Gaps = 18/803 (2%)
Query: 2296 MKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANL 2355
+ ++I++ + + ++S LE R+ YLND+ TY +Y CR+LFE+ KLLFSF +CA +
Sbjct: 3635 LDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKI 3694
Query: 2356 LLARKEIEYQELMFLLTGGVSL--KSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHF 2413
L ++ E F L GGV L + NP +WL D W+ I + F GL F
Sbjct: 3695 LETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSF 3754
Query: 2414 CEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGK 2473
++ +W Y + P A P + NE+Q+++I+R LR D++ +T+++ LG
Sbjct: 3755 EQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGS 3814
Query: 2474 KFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQ 2533
+F+EPP ++ DS PL+F+LSPG DP ++LL+ A M+ +F A+SLGQGQ
Sbjct: 3815 RFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMA-QRFHALSLGQGQ 3873
Query: 2534 GPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK 2593
PIAA++++ + +G WV L NCHL++SWMP L+K+ E E + SFRLWL+S P
Sbjct: 3874 APIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD 3933
Query: 2594 FPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFH 2653
FP++ILQ +KMT EPP GL+ N+ + Y +S+P+F + C K ++KLLF +CFFH
Sbjct: 3934 FPISILQVSIKMTTEPPKGLKANMTRLYQL--MSEPQFSR-C-SKPAKYKKLLFSLCFFH 3989
Query: 2654 ALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRV 2713
+++ ERKKF LGWNI YGFN+SD +S L L+++EY+ P++A+ YL NYGG V
Sbjct: 3990 SVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHV 4049
Query: 2714 TDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPE 2773
TDDWDRRLL T + D++ + P ++ S YF P G+ Y E+I LP PE
Sbjct: 4050 TDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPE 4109
Query: 2774 IFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGST-DQILLEITKDILNKLPSDF 2832
FG H N D++ + + +TLF++LL Q T A G T ++ +LE+ D+ K+P
Sbjct: 4110 AFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMI 4169
Query: 2833 DIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALS 2892
D E +K +N VL+QE++R+N L+ TI +L DLEK I+G++VM ++LE +
Sbjct: 4170 DYE-GTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIF 4228
Query: 2893 GSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGK-PCVFWLSGFFFTQA 2951
+ VP +W K +YPS KPL ++ D R+ + W + + P +FWLSGF F
Sbjct: 4229 NCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTG 4287
Query: 2952 FLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDT--SPEDGVYIHGLYLDGARWDRESGL 3009
FLT +Q+ AR+ +D L +EF V D S+ P+DGV++ GLYL+GA WDR++
Sbjct: 4288 FLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSC 4347
Query: 3010 LAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAML 3069
L E P L LMP I +P + + Y CP Y R G + +FVI +
Sbjct: 4348 LVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASFVIGID 4403
Query: 3070 LKTDQPT-RHWIKRGVALLCQLD 3091
L++ T HWIKRG ALL LD
Sbjct: 4404 LRSGAMTPDHWIKRGTALLMSLD 4426
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 1093 bits (2828), Expect = 0.0
Identities = 694/2095 (33%), Positives = 1125/2095 (53%), Gaps = 115/2095 (5%)
Query: 260 MNTWYPKVINLFTKKEAL----EGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF 315
M WY + L TK E L K KL ++Y + L L+ + ++ F L
Sbjct: 828 MVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLI 887
Query: 316 DPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTS 375
+P+F E ++ +P +++ V E ++ W++G+
Sbjct: 888 ----LGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKH---FVRWMNGSC 940
Query: 376 TP-------------VNL--DTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYN- 419
+N D L ++ AV + VHR L K+ + + ++Y
Sbjct: 941 IECPPQKGEEEEVVIINFYNDISLNPQIIEQAV-MIPQNVHRILINLMKYLQKW-KRYRP 998
Query: 420 -WLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKT 478
W LD V +E F + Y E ++ + +A E+M P +RL L
Sbjct: 999 LWKLDKAIV--MEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLAN 1056
Query: 479 GLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKAR 538
+ AK++ L + ++E + E E + ++ K+P T E++ +++ + + R
Sbjct: 1057 TVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIR 1116
Query: 539 TVG-IEELILR-IQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIEN 596
+ + EL R +QE R M+ + ++F E ++ +W N + L +
Sbjct: 1117 SKSLVMELRYRDVQERYRTMAMY-NLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDI 1175
Query: 597 AKHKKE---NELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESE 653
+ E E+M R ++IE+ ++R + + + + V + ++ + E
Sbjct: 1176 KRTFTELTRGEIMNYR----VQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHE 1231
Query: 654 EAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNG 713
++ Q + E+LF +T YPEL K++ + + + + +++ W +++LN
Sbjct: 1232 KSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNV 1291
Query: 714 ESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR 773
+ ++ +E F R + K + + E + A K S+ + + K+ A
Sbjct: 1292 QILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIP---LLLDLKNEA------ 1342
Query: 774 MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
+R RHWK++ E TL + + L + + I A KE ++EKA+ +
Sbjct: 1343 LRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEI 1402
Query: 834 IGTWEDIAFHISLY----RDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIK 889
+ TWE++ F + Y ++ G IL SVDEI LDD Q++ GS F+ PF +
Sbjct: 1403 LDTWENMKFTVVKYCKGTQERGY-ILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVH 1461
Query: 890 AWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFC 949
WE L I E I+ W+ VQ +W+YLE IF DI Q+PEE ++F +D+ ++ IM
Sbjct: 1462 KWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGET 1521
Query: 950 AKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILS 1009
KDP + L LQN +E LEK K LN YL+ KR FPRFFF+S+DE+L IL
Sbjct: 1522 LKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG 1581
Query: 1010 ETKDPLRVQPHLKKCFEGIAKLEFLPNLD----IKAMYSSEGERVELIALISTSAARGAV 1065
+ DPL VQ H+ K ++ IA L F + AM S+EGE +E ++ A G V
Sbjct: 1582 SS-DPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILR---AEGRV 1637
Query: 1066 EKWLIQVEDLMLRSVHDVIAAARLAYPESARR-DWVREWPGQVVLCISQMFWTSETQEVI 1124
E W+ V + M R+ + A Y E R DW+ + G VVL SQ++WT E ++V
Sbjct: 1638 EDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVF 1697
Query: 1125 ----SGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIK 1180
G + +K Y +++ Q++E+V + LSK R ++ IDVHARD+V I+
Sbjct: 1698 HKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIR 1757
Query: 1181 MGVSHDTDFLWLAQLRYYWENENARVRIINCN--VKYAYEYLGNSPRLVITPLTDRCYRT 1238
+ +F W +QLR+YW+ E + I C Y YEY+G + RLVITPLTDR Y T
Sbjct: 1758 GSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLT 1817
Query: 1239 LIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASS 1298
L A + LGGAP GPAGTGKTETTKDLAKAL + CVV NC +G+DY A+GK F GLA
Sbjct: 1818 LTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQC 1877
Query: 1299 GAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPG 1358
GAW CFDEFNRI+ VLSV++ QI I+ A+ +L F FEG E+ L+ + ITMNPG
Sbjct: 1878 GAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPG 1937
Query: 1359 YAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLS 1418
YAGR+ELP+++K LFR V ++VP+ I EI L+S GFL A+ L+ K+ + Y+L EQLS
Sbjct: 1938 YAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLS 1997
Query: 1419 SQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITS 1478
Q+HYD+G+RA+K+VLV AG LK + ED++L+R+++D+N PKF+ D+PLF G+ S
Sbjct: 1998 KQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLIS 2057
Query: 1479 DLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFA 1538
DLFPG+ P Y +F + + + + ++K++Q +E M+ RH M+VG
Sbjct: 2058 DLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRG 2117
Query: 1539 AKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVAN 1598
K+ V++ L T + G K+ +NPK++++ +L+G DP + +WTDG+++N
Sbjct: 2118 GKSVVINTLCQAQTKL-----GLTTKLY--ILNPKAVSVIELYGILDPTTRDWTDGVLSN 2170
Query: 1599 TFREF-ALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFE 1657
FRE ++ +RK+++FDG +D LW+E+MN+V+DDN+ L L +GE I++ +L+FE
Sbjct: 2171 IFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFE 2230
Query: 1658 TMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIP 1717
DL ASPATVSRCGM+Y++P L + P W+N + + + +L +L+
Sbjct: 2231 VGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMD 2290
Query: 1718 PSLNQRVELFQLNYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIF 1777
+ V+ Q L T + L + ++ K + + L + F+
Sbjct: 2291 VIVEGIVDGRQAEKLKTIVPQTDLNM-----VTQLAKMLDALLEGEIEDLDL-LECYFLE 2344
Query: 1778 SLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKG---LVYDYMY 1834
+L S+G S DGR FD +I+ + D+ G W P + G +YD+ +
Sbjct: 2345 ALYCSLGASLLEDGRMKFDEYIKRLA-----SLSTVDTEGVWANPGELPGQLPTLYDFHF 2399
Query: 1835 ELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPT 1894
+ K + +WV W++L+ + + K +I+V T+DT R T++++ + +P++FVG +
Sbjct: 2400 DNK-RNQWVPWSKLVPE-YIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGES 2457
Query: 1895 GTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKK 1954
GT K+ ++ L N L ++ +N S+RT++ +Q + A ++KR K +GPPMGK+
Sbjct: 2458 GTSKTATTQNFLKN-LSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKR 2516
Query: 1955 CIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDL-KDTSKITLVDIELIAAMGPPGG 2013
++F+DDMNMP +++YG Q PI LL+ + G+ YD K+ + ++ D+ IAAMG GG
Sbjct: 2517 LLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG 2576
Query: 2014 GRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTME 2073
GRN V PR I F++ ++ S+E++ I+SSI+ + T F + ++ T+
Sbjct: 2577 GRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTLA 2634
Query: 2074 IYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVHEVLRVFYD 2133
+YK V++L PTP+K HY FNLRD SRV G +L + M+R++ +E LRVF+D
Sbjct: 2635 LYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHD 2694
Query: 2134 RLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLE 2193
RLI++ D++ + Q +++ +HFK+ + ++FGD+ E
Sbjct: 2695 RLISETDKQLVQQHIGSLVVEHFKDDVEVVMRD--------------PILFGDFQMALHE 2740
Query: 2194 GDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNA 2253
G+ R+Y +I + + + L+EYN+++ T+MNLV+F LEHL+R+ R+++ G+A
Sbjct: 2741 GEPRIYEDIQDYEAAKALFQEILEEYNESN-TKMNLVLFDDALEHLTRVHRIIRMDRGHA 2799
Query: 2254 LLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKS-FIAVPVTNR 2307
LLVG+GGSG+QSL+RLA A +F+ +S+ Y N +RED+KS ++ + + N+
Sbjct: 2800 LLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENK 2854
Score = 481 bits (1239), Expect = e-135
Identities = 268/790 (33%), Positives = 426/790 (53%), Gaps = 26/790 (3%)
Query: 2315 ILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGG 2374
IL KRLR + D T+++Y + C LFE+ KLLFSF + + A + +EL F L G
Sbjct: 3695 ILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGN 3754
Query: 2375 VSLKSAEKNPDPTWLQDKSWEEICRASEFPA--FRGLRQHFCEHIYEWREIYDSKEPHNA 2432
+SL+ +++ WL D+ WE+I SE + F L + W+E YD
Sbjct: 3755 ISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQF 3814
Query: 2433 KFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNC 2492
P D N+ QK++ILRC R D++ A+T+YVT +G+K+V+PP + S
Sbjct: 3815 PVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTP 3874
Query: 2493 TIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVC 2552
P++F+LSPG+DP L+K A GN+ + +++GQGQ +A ++++ A+ G W+
Sbjct: 3875 HSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQWLM 3934
Query: 2553 LQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTG 2612
LQNCHL V W+ LEK E T + FRLWLT+ P+ FP+ ILQ +K+ EPP G
Sbjct: 3935 LQNCHLLVKWLKDLEKSLERITKP--HPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNG 3992
Query: 2613 LRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYG 2672
L+LN+ +Y E C A++ L++ + FFHA+VQER+KFG +GWN+ Y
Sbjct: 3993 LKLNMRATYFK---ISHEMLDQC--PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYD 4047
Query: 2673 FNESDLRISIRQLQLFINEY-----DTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLA 2727
FNESD ++ + L ++ + IP+ ++ YL GE YGGR D +DRR+L +
Sbjct: 4048 FNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMD 4107
Query: 2728 DFYNLYIVEN---PHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDIS 2784
++ +I + H+ + +Y P E ++E I+ LP PE+FGLH N +I
Sbjct: 4108 EYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIG 4167
Query: 2785 KDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVR 2844
Q + ++ LL Q + ++ + S D + ++ K+I NK+P FD++ ++
Sbjct: 4168 YYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTG 4227
Query: 2845 YEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIW 2904
+ + VL+QE+ERFN L++ + +L +L++A+ G V M + L+ ++ SL +G +P IW
Sbjct: 4228 LSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIW 4286
Query: 2905 AKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKY 2964
+ + +LK LG+++ FL R + W +P V WLSG +++LT +Q RK
Sbjct: 4287 RRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCRKN 4346
Query: 2965 TTPIDLLGYEFEVIPSDTSDTSPE---DGVYIHGLYLDGARWDRESGLLAEQYPKLLFDL 3021
P+D +V +D E G ++ GLYL+GA WD E G L + PK+L
Sbjct: 4347 GWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVD 4406
Query: 3022 MPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIK 3081
+PI+ I P + R+ + + P+Y TS R+ + V L T + HW+
Sbjct: 4407 LPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTTRHISHWVL 4461
Query: 3082 RGVALLCQLD 3091
+GV L D
Sbjct: 4462 QGVCLTLNSD 4471
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 976 bits (2523), Expect = 0.0
Identities = 657/2074 (31%), Positives = 1047/2074 (50%), Gaps = 200/2074 (9%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLED-NVLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 901 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 960
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424
+D E ++ + ++ E + Y+ E+Y N+L+ G
Sbjct: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1018
Query: 425 TAV--ENIETFQTED------HTFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475
AV E+++T+ T+D T ++ E I+ + L E+ + + ++ DC
Sbjct: 1019 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077
Query: 476 LKTGLTNKAKAF--------ANILLNDIA-------------SKYRKENECICSEFEAIK 514
K L + + + +N + N +A +K KE + +
Sbjct: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGD--YDGLVEVM 1135
Query: 515 EHALKVPE---TTEEMMD-LISYVEKARTVG---IEELILRIQESKRQMSYFLDVFLFPQ 567
H +KV E T+ M + L +E +T G EE+ L++QE +
Sbjct: 1136 GHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWA--------NT 1187
Query: 568 EDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFT 627
+ LA+ + + P + N + + +K + K+ + +E R E
Sbjct: 1188 KKLAIQVKLTVAPLQANEV---------SILRRKCQQFELKQHEF-----RERFRREAPF 1233
Query: 628 EFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQ 687
F++ + + + QK I E ++ ++K LF+ + Y +L + +
Sbjct: 1234 SFSDPNPYK----SLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLK 1289
Query: 688 KFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQE 744
+ ++ V+ S + W + D+N E M+ D ++F+ R + K +K + + +
Sbjct: 1290 ELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTV 1349
Query: 745 KRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKL 804
K R++ E + +R RHW+Q+ + TTL +L+L
Sbjct: 1350 KNVITSLRAVSE------------LQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQL 1397
Query: 805 NLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAI 864
NL Y ++ I A KE +EK + + TW + F + TG +L S + +
Sbjct: 1398 NLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVET 1457
Query: 865 LDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SED 923
L+D ++ Q + S ++ F E+ +W+ +L I W +VQ W +LE IF SED
Sbjct: 1458 LEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSED 1517
Query: 924 IMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLN 983
I Q+P + ++F +++ ++ +M+ K P V+ ATS GL KL+ + L K L
Sbjct: 1518 IRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALA 1577
Query: 984 AYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK--- 1040
YLE KRL FPRF+F+S+ ++L+ILS DP+ V HL K F+ + KL+F + K
Sbjct: 1578 EYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLK 1637
Query: 1041 ---AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARR 1097
MYS E E + S G VE WL +V D M ++ I A + Y E R
Sbjct: 1638 VGLGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE 1694
Query: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKL 1153
W+ ++P QV L +Q++WT+E + EG ++ Y K+ +QLN ++ L+ G L
Sbjct: 1695 QWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNL 1754
Query: 1154 SKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINC 1211
+ R + + TIDVHARDVV MI V F W AQLR+ W+ E I +
Sbjct: 1755 NAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDA 1814
Query: 1212 NVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALA 1271
++Y+YEYLGN+PRLVITPLTDRCY TL + +L +GGAP GPAGTGKTETTKDL +AL
Sbjct: 1815 QIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALG 1874
Query: 1272 VQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQ 1331
VFNCS+ +DY + G +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+
Sbjct: 1875 TMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRA 1934
Query: 1332 KLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISL 1391
K F F G + L P + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L
Sbjct: 1935 KKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIML 1994
Query: 1392 YSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDI 1451
+ GFL AR L+ K + Y LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED
Sbjct: 1995 MAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQ 2054
Query: 1452 LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVK 1511
+L+R+++D N PK ++ D+P+F G+ DLFP + +P F + ++ LQ
Sbjct: 2055 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2114
Query: 1512 FFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVN 1571
F+ K++Q E++ VRH +VG + K++VL L T + + K + ++
Sbjct: 2115 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLD 2167
Query: 1572 PKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTV 1631
PK++T +LFG +PV+ EW DG+ + R+ A KW++ DG ID +WIES+NTV
Sbjct: 2168 PKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTV 2227
Query: 1632 LDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSW 1691
+DDNK L L S E I ++ M L+FE L A+PATVSR G++Y+ P+ LGW P+VSSW
Sbjct: 2228 MDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSW 2287
Query: 1692 LNSLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRI 1749
+ K +A L LF +P L++ R ++ + T++ IL +L
Sbjct: 2288 IERRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2343
Query: 1750 SNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDE 1809
K VP + + + F+F+ W+ GG+ D ++ D +
Sbjct: 2344 E---KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF-------- 2384
Query: 1810 NPVPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQD 1863
KW F +G ++DY + K +++ W + + + L D + +Q
Sbjct: 2385 -------SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQA 2435
Query: 1864 IIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLS 1923
+V T +TIR + MDL + + P++ VG GTGKSV + DKL L D Y + +
Sbjct: 2436 SLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFN 2494
Query: 1924 ARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFF 1983
T++ +Q ++ L+K+ +GPP KK + FIDDMNMP ++KYG P L+RQ
Sbjct: 2495 FYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHM 2554
Query: 1984 DCGHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMV 2040
D HWY D K+TL DI + +A M P G + R RHF + +++ E +
Sbjct: 2555 DHRHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALT 2610
Query: 2041 RIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100
I+++I+ +L I +Q+V + ++++ LPT K HY FNLRD S
Sbjct: 2611 TIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSN 2670
Query: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE-- 2158
+ +G L + + ++RL++HE RV+ D+++++ D+ L ++T K F +
Sbjct: 2671 IFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLG 2730
Query: 2159 -----SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVD 2213
+ +IF H + D Y+ + ++ + ++
Sbjct: 2731 DELLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLV 2767
Query: 2214 QCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSM 2273
LD YN+ + MNLV+F + H+ RI R+L+ GNALLVG+GGSG+QSL+RLA +
Sbjct: 2768 DVLDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYI 2826
Query: 2274 AKMHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306
+ + +FQ + K YG+ + + D+ + +I V N
Sbjct: 2827 SGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860
Score = 446 bits (1147), Expect = e-124
Identities = 271/787 (34%), Positives = 423/787 (53%), Gaps = 35/787 (4%)
Query: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
+++R+ L D TY++Y R LFE+DKL+F + +L +KE+ EL FLL
Sbjct: 3707 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3764
Query: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
K+ +P +LQ + W I SE F+ L W+++ +S+ P FP
Sbjct: 3765 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3823
Query: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
KN LQK+ ++RCLRPD++T AI N+V +K+G KFVE + +KSY +S+ +
Sbjct: 3824 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3882
Query: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
+ F+LSPG DP+ + ++ K +SLGQGQ +A + A E+G WV L
Sbjct: 3883 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3942
Query: 2554 QNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQNGVKMTNE 2608
QN HL W+ L+K E +++ + + +R+++++ P+ P IL+N +K+TNE
Sbjct: 3943 QNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQGILENAIKITNE 4001
Query: 2609 PPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWN 2668
PPTG+ NL ++ + + + C KE+ ++ +LF +C+FHA+V ER+KFG GWN
Sbjct: 4002 PPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERRKFGAQGWN 4057
Query: 2669 IPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLAD 2728
Y FN DL ISI L ++ +P++ + YL GE YGG +TDDWDRRL T LA+
Sbjct: 4058 RSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAE 4117
Query: 2729 FYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQ 2788
+ ++E +P + PP Y+ Y E+I + + P ++GLH N +I
Sbjct: 4118 YIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTV 4174
Query: 2789 QTKTLFESLLLTQGGSKQTGASG--STDQILLEITKDILNKLPSDFDIEMALRKYPVRYE 2846
++ LF ++L Q +GA S ++ + + DIL K+P F++ + K +
Sbjct: 4175 TSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAK--AAEK 4232
Query: 2847 ESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAK 2906
V QE ER N L +R +L++L +KG + + + +E LS +L VP+ W
Sbjct: 4233 TPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVA 4292
Query: 2907 RSYPSLKPLGSYITDFLARLNFLQDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYT 2965
R+YPS+ L ++ D L R+ L+ W P WL+GFF Q+FLT MQ+ ARK
Sbjct: 4293 RAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE 4352
Query: 2966 TPIDLLGYEFEVIPSDTSDTS--PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMP 3023
P+D + EV + D + P +G Y++GL+++GARWD ++G++AE K L MP
Sbjct: 4353 WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMP 4412
Query: 3024 IIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRG 3083
+I+IK R+ + Y CP+YKT R T +V LKT + WI
Sbjct: 4413 VIFIKAIPVDRMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAA 4463
Query: 3084 VALLCQL 3090
VALL Q+
Sbjct: 4464 VALLLQV 4470
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 969 bits (2505), Expect = 0.0
Identities = 647/2043 (31%), Positives = 1047/2043 (51%), Gaps = 162/2043 (7%)
Query: 324 PIFKIELTFDDDKMEFYPTFQD-LEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDT 382
PIF+ +L+ ++ FYP+ + ++ +VE + ++ + ++ LS + +
Sbjct: 918 PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977
Query: 383 EL---PEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETF------ 433
+L P+ L TL V R + G Y++ +Y++L E + F
Sbjct: 978 DLDGIPD--LANMRRTLMERVQRMM-GLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHI 1034
Query: 434 ----QTEDHTFD----------EYTEFIEKFLSLASEIMLL-PQWIHYTMVRLDCEDLKT 478
+ EDH D ++ I+ + +L E+ L P + +++D K
Sbjct: 1035 LTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKA 1094
Query: 479 GLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKAR 538
L N K ++ + + + +A +K E+ L+ VEK
Sbjct: 1095 SLLNIIKRWSLLFKQHLVDHVTHS----LANLDAF----IKKSES-----GLLKKVEKGD 1141
Query: 539 TVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKI-NPIFDENDELIENA 597
G+ E++ + K + S ++F ++ + L T + +++ +F + +EL E
Sbjct: 1142 FQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKT---YEQELPETVFKQLEELPEKW 1198
Query: 598 KHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQY------------------V 639
+ K+ + K++ L+ + + + T F + E+ Q + +
Sbjct: 1199 NNIKKVAITVKQQVAPLQANEVTLLRQRCTAF-DAEQQQFWEQFHKEAPFRFDSIHPHQM 1257
Query: 640 TDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRS 699
D R ++ IQ+ E + I++ LF+ + Y +L + + + ++ ++ + S
Sbjct: 1258 LDARHIE--IQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSS 1315
Query: 700 EKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKI 759
W + ++N E+ME + ++F+R I L KE++ S +
Sbjct: 1316 IHAWETTPWRNINVEAMELECKQFARHI--------RNLDKEVRAWDAFTGLESTVWNTL 1367
Query: 760 EEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAG 819
+ A + +R RHW+Q+ + G T D TTL +L+L L Y ++ I
Sbjct: 1368 SSL-RAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDK 1426
Query: 820 ASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSP 879
A+KE +EK + + TW + F + T V +L S +++ +L+D ++ Q + S
Sbjct: 1427 AAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSK 1486
Query: 880 FIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIMQQMPEEGRQFQTV 938
++ F E+ W+ +L + I W +VQ W +LE IF SEDI Q+P++ ++F+ +
Sbjct: 1487 YVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGI 1546
Query: 939 DRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFF 998
D ++++ K P V+ T+ GL EKL++ L K L YL+ KRL FPRF+F
Sbjct: 1547 DIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYF 1606
Query: 999 LSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFL------PNLDIKAMYSSEGERVEL 1052
LS+ ++L+ILS P +VQ HL K F+ +AK+ F P MYS E E V
Sbjct: 1607 LSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYV-- 1664
Query: 1053 IALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCIS 1112
A G VE WL V M +V + AY E R W+ + P QV L +
Sbjct: 1665 -AFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCT 1723
Query: 1113 QMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTID 1168
Q++WT+E + EG +K YYK+ QL ++ ++ G+LSK R + + TID
Sbjct: 1724 QIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTID 1783
Query: 1169 VHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYAYEYLGNSPRL 1226
VHARDVV MI V + FLWL+QLR+ W++E + I + Y+YEYLGN+PRL
Sbjct: 1784 VHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRL 1843
Query: 1227 VITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYL 1286
VITPLTDRCY TL + +L + GAP GPAGTGKTETTKDL +AL + VFNCS+ +DY
Sbjct: 1844 VITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYK 1903
Query: 1287 AMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLN 1346
+ G +KGLA +GAW CFDEFNRI +EVLSVVA Q+ IQ AI+ K F F G E+ LN
Sbjct: 1904 SCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLN 1963
Query: 1347 PNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKI 1406
P+ + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L + GF+ A+ L+ K
Sbjct: 1964 PSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKF 2023
Query: 1407 VMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFL 1466
+ Y+LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED +L+RS++D N PK +
Sbjct: 2024 ITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIV 2083
Query: 1467 SHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIV 1526
+ D+P+F G+ DLFP + +P F +A LQ F+ K++Q E++ V
Sbjct: 2084 TDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAV 2143
Query: 1527 RHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDP 1586
RH +VG K++VL L T +M + + ++ +NPK++T +LFG +P
Sbjct: 2144 RHSVFVVGGAGTGKSQVLRSLHKTYQIM-------KRRPVWTDLNPKAVTNDELFGIINP 2196
Query: 1587 VSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEII 1646
+ EW DG+ ++ RE A KW++ DG ID +WIES+NTV+DDNK L L S E I
Sbjct: 2197 ATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERI 2256
Query: 1647 QMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQA 1706
++P M L+FE L A+PATVSR G++Y+ P+ LGW P VSSW+ + + E +A
Sbjct: 2257 PLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKRE---IQTE-RA 2312
Query: 1707 LLRGLFAWLIPPSLNQRVELFQL-----NYLYTTIVSKILKILITFRISNYFKYVPLKTQ 1761
L LF +P L+ F+ +V +L+ L+T + +P
Sbjct: 2313 NLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT------TEDIPADCP 2366
Query: 1762 CTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKW-- 1819
+ + F+F+ IW+ GG+ + +D KW
Sbjct: 2367 KEIYEHY------FVFAAIWAFGGA-----------------MVQDQLVDYRAEFSKWWL 2403
Query: 1820 ----ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYT 1875
F +G ++DY + + K ++ W++L+ D ++ +Q +V T +TIR
Sbjct: 2404 TEFKTVKFPSQGTIFDYYIDPETK-KFEPWSKLVPQFEF-DPEMPLQACLVHTSETIRVC 2461
Query: 1876 FLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNII 1935
+ M+ + +P++ VG GTGKSV V KL + L+ + Y + + T++ +Q ++
Sbjct: 2462 YFMERLMARQRPVMLVGTAGTGKSVLVGAKLAS-LDPEAYLVKNVPFNYYTTSAMLQAVL 2520
Query: 1936 MARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTS 1995
L+K+ +GPP KK I FIDDMNMP ++ YG P ++RQ D GHWYD S
Sbjct: 2521 EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS 2580
Query: 1996 KITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHE 2055
+ +++ ++ M P G + PR RHF++ ++ + + I+S I+ +L+
Sbjct: 2581 LKEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGN 2639
Query: 2056 FPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVAN 2115
FP +++ + +++ LPT K HY FNLRDF+ + +G L + V +
Sbjct: 2640 FPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKS 2699
Query: 2116 KHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVT 2175
+IRL++HE RV+ D+++ + D F L + + K++F I PV
Sbjct: 2700 TWDLIRLYLHESNRVYRDKMVEEKD----FDLFDKIQTEVLKKTFDDI-------EDPVE 2748
Query: 2176 EEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYV 2235
+ NL Y + + Y+ + + + + + L+ +N+ + T M+LV+F
Sbjct: 2749 QTQSPNL----YCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDA 2803
Query: 2236 LEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWRED 2295
+ H+ I R+L+ GNALLVG+GGSG+QSLTRLA ++ M +FQ + K Y + +++ D
Sbjct: 2804 MRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMD 2863
Query: 2296 MKS 2298
+ S
Sbjct: 2864 LAS 2866
Score = 436 bits (1122), Expect = e-121
Identities = 274/843 (32%), Positives = 429/843 (50%), Gaps = 43/843 (5%)
Query: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRY 2322
R+ A + ++ ++SK + M ++ S + R ++S L +R+
Sbjct: 3672 REHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDES--LRERVAN 3729
Query: 2323 LNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEK 2382
L D T+++Y R LFE DKL + L +LL +E+ EL FLL V +A
Sbjct: 3730 LIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASP 3789
Query: 2383 NPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNL 2442
+L ++W + S F L + W++ +S+ P K P KN
Sbjct: 3790 ---VEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEW-KNK 3845
Query: 2443 NELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSP 2502
LQ++ +LR +RPD++T A+ ++V +KLG K+V D S+ +S P+ F+LSP
Sbjct: 3846 TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSP 3905
Query: 2503 GADPMASLLKFANDKSMSGNK--FQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAV 2560
G DP+ + + N F +SLGQGQ +A + A ++G WV LQN HL
Sbjct: 3906 GVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVA 3965
Query: 2561 SWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQNGVKMTNEPPTGLRL 2615
W+ LEK E+ SE + FR+++++ P+ P IL+N +K+TNEPPTG+
Sbjct: 3966 KWLSTLEKKLEEH-SENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHA 4024
Query: 2616 NL---LQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYG 2672
NL L ++ D + +E ++ +LF +C+FHA+V ER+KFGP GWN Y
Sbjct: 4025 NLHKALDNFTQDTLE-------MCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
Query: 2673 FNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNL 2732
FN DL IS+ L F+ +P++ + YL GE YGG +TDDWDRRL T L +F
Sbjct: 4078 FNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRP 4137
Query: 2733 YIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKT 2792
++E + S + + P Y Y ++I + P ++GLH N +I Q ++
Sbjct: 4138 EMLEG---ELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEK 4194
Query: 2793 LFESLLLTQGGSKQT--GASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMN 2850
LF ++L Q Q GA + ++ + + ++IL ++ +F+I + K V
Sbjct: 4195 LFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAK--VEERTPYI 4252
Query: 2851 TVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYP 2910
V QE R N L I+ +LR+LE +KG + M S +E L +L VPE WA+R+YP
Sbjct: 4253 VVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYP 4312
Query: 2911 SLKPLGSYITDFLARLNFLQDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPID 2969
S L ++ D L R+ L+ W P WL+GFF Q+FLT MQ+ ARK P+D
Sbjct: 4313 STAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLD 4372
Query: 2970 LLGYEFEVIPSDTSD--TSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWI 3027
+ + ++ + + + P +G YIHGL+++GA WD ++G++ E K L MP+++I
Sbjct: 4373 QMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFI 4432
Query: 3028 KPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALL 3087
K + Y CP+YKTS+R T +V LKT + W+ GVALL
Sbjct: 4433 KAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSKWVLAGVALL 4483
Query: 3088 CQL 3090
Q+
Sbjct: 4484 LQI 4486
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 965 bits (2495), Expect = 0.0
Identities = 599/1732 (34%), Positives = 928/1732 (53%), Gaps = 112/1732 (6%)
Query: 604 ELMAKREKLILEIEKESRRMEEFTEFAELE-RMQQYVTDVRQLQKRIQESEEAVQFINKE 662
E+ R+K IL K++ E F +A L + T + + + ++ EE + + +
Sbjct: 1243 EVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQES 1302
Query: 663 EELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEE 722
LF+ L +Y ++ + + I+ + ++ ++ +RS W + ++ E M+ ++
Sbjct: 1303 TRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRR 1362
Query: 723 FSR--------EIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRM 774
F++ + K ++ + E K A R++ E + +
Sbjct: 1363 FAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITE------------LQSPAL 1410
Query: 775 RARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMI 834
R RHW Q+ + +G + TTL +L L L + I A KE EK + +
Sbjct: 1411 RDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEIS 1470
Query: 835 GTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDR 894
TW + F ++ TG+ +L S +++ L+ ++ QT+ S +++ F ++ +W+++
Sbjct: 1471 QTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNK 1530
Query: 895 LIRIQETIDEWLKVQAQWLYLEPIF-CSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDP 953
L I W++VQ W +LE IF CSEDI Q+ ++ R+F VD ++++M AK
Sbjct: 1531 LNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVE 1590
Query: 954 KVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKD 1013
VL AT L EKL++ L K L YLE KR+ FPRF+F+S+ ++L+ILS+
Sbjct: 1591 NVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQ 1650
Query: 1014 PLRVQPHLKKCFEGIAKLEFLPNLDIKA-----MYSSEGERVELIALISTSAARGAVEKW 1068
P +V HL K F+ IA L+F N D+ A MYS E E V A G VE W
Sbjct: 1651 PKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQA---ECECVGHVETW 1707
Query: 1069 LIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGT 1128
L+Q+E M +V I A +AY E R W+ ++P QV L SQ++WT++ S
Sbjct: 1708 LLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLE 1767
Query: 1129 EG----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMI--KMG 1182
EG LK ++K+ +QLN ++ L+ G+L R + + TIDVHARDVV +I K
Sbjct: 1768 EGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQV 1827
Query: 1183 VSHDTDFLWLAQLRYYWEN--ENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLI 1240
V F WL+QLR+ WE+ ++ V I + +Y YEYLGNSPRLVITPLTDRCY TL
Sbjct: 1828 VVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLT 1887
Query: 1241 GAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGA 1300
+ +L + GAP GPAGTGKTETTKDL +AL + VFNCS+ +DY ++G +KGL +GA
Sbjct: 1888 QSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGA 1947
Query: 1301 WACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYA 1360
W CFDEFNRI +EVLSVVA Q+ I AI+ + FVF G + L P+ + ITMNPGYA
Sbjct: 1948 WGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYA 2007
Query: 1361 GRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQ 1420
GR+ELP+NLK LFR AM+ P+ LI EI L + GF++AR L+ K + Y LC E LS Q
Sbjct: 2008 GRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQ 2067
Query: 1421 FHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDL 1480
HYD+G+RA+K+VLV AG+LK N ED +L+R+++D N PK ++ DIP+F G+ DL
Sbjct: 2068 DHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDL 2127
Query: 1481 FPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAK 1540
FP + +P F + ++ LQP + F+ K++Q E++ VRH +VG K
Sbjct: 2128 FPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGK 2187
Query: 1541 TKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTD------- 1593
+K+L L T M ++K ++ +NPK++T +LFG + EW D
Sbjct: 2188 SKILRTLNRTYVNM-------KQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSY 2240
Query: 1594 --GIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQ 1651
G+ ++ RE A + KW+V DG ID +WIES+NTV+DDNK L L S E I ++P
Sbjct: 2241 FIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPF 2300
Query: 1652 MSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGL 1711
M L+FE L A+PATVSR G++Y+ P LGW P V+SW++ + +A L L
Sbjct: 2301 MRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR----HQSEKANLTIL 2356
Query: 1712 FAWLIPPSLNQ-RVELFQLNYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLH 1770
F +P L++ R + + + + + L +L+ ++ + VP + + +
Sbjct: 2357 FDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTP--ENVPSDSPKEVYEVY-- 2412
Query: 1771 QQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKW------ECPFD 1824
F+F+ IW+ GG+ L +D + +W F
Sbjct: 2413 ----FVFACIWAFGGT-----------------LLQDQISDYQADFSRWWQKEMKAVKFP 2451
Query: 1825 EKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITY 1884
+G ++DY + K K + + W + I + D + +Q ++V T +T R + M+L +
Sbjct: 2452 SQGTIFDYYVDHKTK-KLLPWADKIAQFTM-DPDVPLQTVLVHTTETARLRYFMELLLEK 2509
Query: 1885 AKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRK 1944
KPL+ VG G GK+V+V D L + E Y + + T++ +Q I+ L+K+
Sbjct: 2510 GKPLMLVGNAGVGKTVFVGDTLASLSE--DYIVSRVPFNYYTTSTALQKILEKPLEKKAG 2567
Query: 1945 GVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIEL 2004
+GP KK I FIDDMNMP ++ YG P L+RQ D GHWYD + + + +
Sbjct: 2568 HNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQY 2627
Query: 2005 IAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIG 2064
+A M P G + PR RHF + + N S + + I+ I +F+ + F P G
Sbjct: 2628 VACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSG 2686
Query: 2065 NQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFV 2124
++ T+ ++ + N LPT K HY FNLRD S V +G L + + +I L++
Sbjct: 2687 PTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWL 2746
Query: 2125 HEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMF 2184
HE RV+ D+LI+ D LFQ + +++ +K F I SH+ + ++ L F
Sbjct: 2747 HESARVYGDKLIDKKDCD-LFQ--RRMLETAYK-YFEGIDSHM------LLQQPLIYCHF 2796
Query: 2185 GDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICR 2244
D G D Y+ + + ++ + LD YN+ + M+LV+F ++H+ RI R
Sbjct: 2797 AD------RGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFEDAMQHVCRISR 2849
Query: 2245 VLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDM 2296
+L+ G ALLVG+GGSG+QSL+RLA + + +FQ +++ YG+ E R D+
Sbjct: 2850 ILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDL 2901
Score = 434 bits (1116), Expect = e-121
Identities = 270/798 (33%), Positives = 423/798 (53%), Gaps = 37/798 (4%)
Query: 2306 NRIVDNKSKI--LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIE 2363
+R ++ K+ ++ R+ L + T+ ++ ++LFEKDKL F + +LL +KEI+
Sbjct: 3748 HRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEID 3807
Query: 2364 YQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREI 2423
EL FLL +++ +P +L +SW I + FRG+ + +WR+
Sbjct: 3808 PLELDFLLR--FTVEHTHLSP-VDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKW 3864
Query: 2424 YDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDL 2483
+S+ P K P K + +QK+I+LR +RPD++T A+ N+V +KLG K+VE DL
Sbjct: 3865 VESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDL 3923
Query: 2484 TKSYLDSNCTIPLIFVLSPGADPMASL--LKFANDKSMSGNKFQAISLGQGQGPIAAKMI 2541
K++ +S+ P+ F+LSPG D + L L ++ KF +SLGQGQ +A +
Sbjct: 3924 VKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVAL 3983
Query: 2542 KAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPV 2596
+ A + G WV LQN HL W+ LEK+ E F S+ + +R+++++ + P
Sbjct: 3984 EKASKGGHWVILQNVHLVAKWLGTLEKLLERF-SQGSHRDYRVFMSAESAPTPDEHIIPQ 4042
Query: 2597 TILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALV 2656
+L+N +K+TNEPPTG+ NL + D + + C KE ++ +LF +C+FHA V
Sbjct: 4043 GLLENSIKITNEPPTGMLANLHAALYN---FDQDTLEIC-SKEQEFKSILFSLCYFHACV 4098
Query: 2657 QERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDD 2716
R +FGP GW+ Y FN DL I L ++ +P+E + YL GE YGG +TDD
Sbjct: 4099 AGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDD 4158
Query: 2717 WDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFG 2776
WDR+L L +F N + E+ + + + APP Y Y ++I+++ + P ++G
Sbjct: 4159 WDRKLCRVYLEEFMNPSLTED---ELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYG 4215
Query: 2777 LHENVDISKDLQQTKTLFESLLLTQGGSKQTG--ASGSTDQILLEITKDILNKLPSDFDI 2834
LH N +I + TLF +LL Q + +G ST++ + + DIL KLP +F++
Sbjct: 4216 LHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNM 4275
Query: 2835 EMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGS 2894
++K R + V QE ER N LI IR +L L+ ++KG + + A+EA +
Sbjct: 4276 AEIMQKNSNRSPYVL--VCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFA 4333
Query: 2895 LLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDW-YNSGKPCVFWLSGFFFTQAFL 2953
L VP+ W+K +YPS L + D L R L W + P V WLSGFF Q+FL
Sbjct: 4334 LSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFL 4393
Query: 2954 TGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS--PEDGVYIHGLYLDGARWDRESGLLA 3011
T MQ ARK P+D +V D P +G Y+HGL+++GARWD ++G +
Sbjct: 4394 TAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIV 4453
Query: 3012 EQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLK 3071
E K L MP+I+ K T R Y CP+Y+T R +++ LK
Sbjct: 4454 EARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR---------GPSYIWTFRLK 4504
Query: 3072 TDQPTRHWIKRGVALLCQ 3089
+++ T W+ GVALL +
Sbjct: 4505 SEEKTAKWVLAGVALLLE 4522
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 954 bits (2467), Expect = 0.0
Identities = 655/2072 (31%), Positives = 1037/2072 (50%), Gaps = 210/2072 (10%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLEDN-VLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 892 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424
+D E ++ + ++ E + Y+ E+Y N+L+ G
Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1009
Query: 425 TAV--ENIETFQTEDH------TFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475
AV E+++T+ T+D T ++ E I+ + L E+ + + ++ DC
Sbjct: 1010 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
Query: 476 LKTGLTNKAKAF--------ANILLNDIASKYRKENECICSEFEAIKE-----------H 516
K L + + + +N + N +A + +KE H
Sbjct: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
Query: 517 ALKVPE---TTEEMMD-LISYVEKARTVGIE---ELILRIQESKRQMSYFLDVFLFPQED 569
+KV E T+ M + L +E +T G E E+ L++QE + +
Sbjct: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWAN--------TKK 1180
Query: 570 LALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEF 629
LA+ + + P + N + + L K ++ L+ + R F
Sbjct: 1181 LAIQVKLTVAPLQANEV----------------SILRRKCQQFELKQHEFRERFRREAPF 1224
Query: 630 AELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKF 689
+ + + L K I E+ ++K LF+ + Y +L + ++
Sbjct: 1225 SFSDPNPYKSLNKVFLLKGIMEA------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
Query: 690 FNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQEKR 746
++ V+ S + W + D+N E M+ D ++F+ R + K +K + + + K
Sbjct: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
Query: 747 KAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNL 806
R++ E + N I R RHW+Q+ + TTL +L+LNL
Sbjct: 1339 VITSLRAVSELQ-------NPAI-----RERHWQQLMQATQVKFKMSEETTLADLLQLNL 1386
Query: 807 TPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD 866
Y ++ I A KE +EK + + TW + F + TG +L S + + L+
Sbjct: 1387 HSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLE 1446
Query: 867 DQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIM 925
D ++ Q + S ++ F E+ +W+ +L I W +VQ W +LE IF SEDI
Sbjct: 1447 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1506
Query: 926 QQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAY 985
Q+P + ++F +++ ++ +M+ K P V+ ATS GL KL+ + L K L Y
Sbjct: 1507 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1566
Query: 986 LEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK----- 1040
LE KRL FPRF+F+S+ ++L+ILS DP+ V HL K F+ + KL+F + K
Sbjct: 1567 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1626
Query: 1041 -AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDW 1099
MYS E E + S G VE WL +V D M ++ I A + Y E R W
Sbjct: 1627 LGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQW 1683
Query: 1100 VREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSK 1155
+ ++P Q+ +WT+E + EG +K Y K+ +QLN ++ L+ G L+
Sbjct: 1684 ILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNA 1736
Query: 1156 QTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINCNV 1213
R + + TIDVHARDVV MI V F W AQLR+ W+ E I + +
Sbjct: 1737 GDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1793
Query: 1214 KYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQ 1273
+Y+YEYLGN+PRLVITPLTDRCY TL + +L +GGAP GPAGTGKTETTKDL +AL
Sbjct: 1794 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1853
Query: 1274 CVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL 1333
VFNCS+ +DY + G +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+ K
Sbjct: 1854 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1913
Query: 1334 VVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYS 1393
F F G + L P + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L +
Sbjct: 1914 KAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMA 1973
Query: 1394 YGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILL 1453
GFL AR L+ K + Y LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED +L
Sbjct: 1974 EGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVL 2033
Query: 1454 LRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFF 1513
+R+++D N PK ++ D+P+F G+ DLFP + +P F + ++ LQ F
Sbjct: 2034 MRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSF 2093
Query: 1514 LEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPK 1573
+ K++Q E++ VRH +VG + K++VL L T + + K + ++PK
Sbjct: 2094 VLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLDPK 2146
Query: 1574 SITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLD 1633
++T +LFG +PV+ EW DG+ + R+ A KW++ DG ID +WIES+NTV+D
Sbjct: 2147 AVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMD 2206
Query: 1634 DNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLN 1693
DNK L L S E I ++ M L+FE L A+PATVSR G++Y+ P+ LGW P+VSSW+
Sbjct: 2207 DNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIE 2266
Query: 1694 SLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRISN 1751
K +A L LF +P L++ R ++ + T++ IL +L
Sbjct: 2267 RRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTE- 2321
Query: 1752 YFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENP 1811
K VP + + + F+F+ W+ GG+ D ++ D +
Sbjct: 2322 --KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF---------- 2361
Query: 1812 VPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDII 1865
KW F +G ++DY + K +++ W + + + L D + +Q +
Sbjct: 2362 -----SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQASL 2414
Query: 1866 VPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSAR 1925
V T +TIR + MDL + + P++ VG GTGKSV + DKL L D Y + +
Sbjct: 2415 VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFNFY 2473
Query: 1926 TSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDC 1985
T++ +Q ++ L+K+ +GPP KK + FIDDMNMP ++KYG P L+RQ D
Sbjct: 2474 TTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDH 2533
Query: 1986 GHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRI 2042
HWY D K+TL DI + +A M P G + R RHF + +++ E + I
Sbjct: 2534 RHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTI 2589
Query: 2043 FSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVI 2102
+++I+ +L I +Q+V + ++++ LPT K HY FNLRD S +
Sbjct: 2590 YNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIF 2649
Query: 2103 RGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE---- 2158
+G L + + ++RL++HE RV+ D+++++ D+ L ++T K F +
Sbjct: 2650 QGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDE 2709
Query: 2159 ---SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQC 2215
+ +IF H + D Y+ + ++ + ++
Sbjct: 2710 LLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLVDV 2746
Query: 2216 LDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAK 2275
LD YN+ + MNLV+F + H+ RI R+L+ GNALLVG+GGSG+QSL+RLA ++
Sbjct: 2747 LDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISG 2805
Query: 2276 MHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306
+ +FQ + K YG+ + + D+ + +I V N
Sbjct: 2806 LDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2837
Score = 427 bits (1097), Expect = e-118
Identities = 273/824 (33%), Positives = 424/824 (51%), Gaps = 72/824 (8%)
Query: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
+++R+ L D TY++Y R LFE+DKL+F + +L +KE+ EL FLL
Sbjct: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3742
Query: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
K+ +P +LQ + W I SE F+ L W+++ +S+ P FP
Sbjct: 3743 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3801
Query: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
KN LQK+ ++RCLRPD++T AI N+V +K+G KFVE + +KSY +S+ +
Sbjct: 3802 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3860
Query: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
+ F+LSPG DP+ + ++ K +SLGQGQ +A + A E+G WV L
Sbjct: 3861 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3920
Query: 2554 Q--------NCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQ 2600
Q N HL W+ L+K E +++ + + +R+++++ P+ P IL+
Sbjct: 3921 QVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQGILE 3979
Query: 2601 NGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERK 2660
N +K+TNEPPTG+ NL ++ + + + C KE+ ++ +LF +C+FHA+V ER+
Sbjct: 3980 NAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERR 4035
Query: 2661 KFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRR 2720
KFG GWN Y FN DL ISI L ++ +P++ + YL GE YGG +TDDWDRR
Sbjct: 4036 KFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR 4095
Query: 2721 LLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHEN 2780
L T LA++ ++E +P + PP Y+ Y E+I + + P ++GLH N
Sbjct: 4096 LCRTYLAEYIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPN 4152
Query: 2781 VDISKDLQQTKTLFESLLLTQGGSKQTGA---------SGSTDQILLE------------ 2819
+I ++ LF ++L Q +GA +GS + E
Sbjct: 4153 AEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGG 4212
Query: 2820 ----------ITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRN 2869
+ DIL K+P F++ + K + V QE ER N L +R
Sbjct: 4213 CPGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRR 4270
Query: 2870 TLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFL 2929
+L++L +KG + + + +E LS +L VP+ W R+YPS+ L ++ D L R+ L
Sbjct: 4271 SLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIREL 4330
Query: 2930 QDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS-- 2986
+ W P WL+GFF Q+FLT MQ+ ARK P+D + EV + D +
Sbjct: 4331 EAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAP 4390
Query: 2987 PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLY 3046
P +G Y++GL+++GARWD ++G++AE K L MP+I+IK R+ + Y CP+Y
Sbjct: 4391 PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
Query: 3047 KTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3090
KT R T +V LKT + WI VALL Q+
Sbjct: 4451 KTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 954 bits (2466), Expect = 0.0
Identities = 654/2072 (31%), Positives = 1037/2072 (50%), Gaps = 210/2072 (10%)
Query: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLEDN-VLSLVERIAEALQNVQTIPSWLSGTSTP 377
D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+
Sbjct: 892 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951
Query: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424
+D E ++ + ++ E + Y+ E+Y N+L+ G
Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1009
Query: 425 TAV--ENIETFQTEDH------TFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475
AV E+++T+ T+D T ++ E I+ + L E+ + + ++ DC
Sbjct: 1010 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
Query: 476 LKTGLTNKAKAF--------ANILLNDIASKYRKENECICSEFEAIKE-----------H 516
K L + + + +N + N +A + +KE H
Sbjct: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
Query: 517 ALKVPE---TTEEMMD-LISYVEKARTVGIE---ELILRIQESKRQMSYFLDVFLFPQED 569
+KV E T+ M + L +E +T G E E+ L++QE + +
Sbjct: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWAN--------TKK 1180
Query: 570 LALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEF 629
LA+ + + P + N + + L K ++ L+ + R F
Sbjct: 1181 LAIQVKLTVAPLQANEV----------------SILRRKCQQFELKQHEFRERFRREAPF 1224
Query: 630 AELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKF 689
+ + + L K I E+ ++K LF+ + Y +L + ++
Sbjct: 1225 SFSDPNPYKSLNKVFLLKGIMEA------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
Query: 690 FNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQEKR 746
++ V+ S + W + D+N E M+ D ++F+ R + K +K + + + K
Sbjct: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
Query: 747 KAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNL 806
R++ E + N I R RHW+Q+ + TTL +L+LNL
Sbjct: 1339 VITSLRAVSELQ-------NPAI-----RERHWQQLMQATQVKFKMSEETTLADLLQLNL 1386
Query: 807 TPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD 866
Y ++ I A KE +EK + + TW + F + TG +L S + + L+
Sbjct: 1387 HSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLE 1446
Query: 867 DQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIM 925
D ++ Q + S ++ F E+ +W+ +L I W +VQ W +LE IF SEDI
Sbjct: 1447 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1506
Query: 926 QQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAY 985
Q+P + ++F +++ ++ +M+ K P V+ ATS GL KL+ + L K L Y
Sbjct: 1507 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1566
Query: 986 LEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK----- 1040
LE KRL FPRF+F+S+ ++L+ILS DP+ V HL K F+ + KL+F + K
Sbjct: 1567 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1626
Query: 1041 -AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDW 1099
MYS E E + S G VE WL +V D M ++ I A + Y E R W
Sbjct: 1627 LGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQW 1683
Query: 1100 VREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSK 1155
+ ++P Q+ +WT+E + EG ++ Y K+ +QLN ++ L+ G L+
Sbjct: 1684 ILDYPAQI-------WWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNA 1736
Query: 1156 QTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINCNV 1213
R + + TIDVHARDVV MI V F W AQLR+ W+ E I + +
Sbjct: 1737 GDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1793
Query: 1214 KYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQ 1273
+Y+YEYLGN+PRLVITPLTDRCY TL + +L +GGAP GPAGTGKTETTKDL +AL
Sbjct: 1794 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1853
Query: 1274 CVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL 1333
VFNCS+ +DY + G +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+ K
Sbjct: 1854 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1913
Query: 1334 VVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYS 1393
F F G + L P + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L +
Sbjct: 1914 KAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMA 1973
Query: 1394 YGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILL 1453
GFL AR L+ K + Y LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED +L
Sbjct: 1974 EGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVL 2033
Query: 1454 LRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFF 1513
+R+++D N PK ++ D+P+F G+ DLFP + +P F + ++ LQ F
Sbjct: 2034 MRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSF 2093
Query: 1514 LEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPK 1573
+ K++Q E++ VRH +VG + K++VL L T + + K + ++PK
Sbjct: 2094 VLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLDPK 2146
Query: 1574 SITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLD 1633
++T +LFG +PV+ EW DG+ + R+ A KW++ DG ID +WIES+NTV+D
Sbjct: 2147 AVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMD 2206
Query: 1634 DNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLN 1693
DNK L L S E I ++ M L+FE L A+PATVSR G++Y+ P+ LGW P+VSSW+
Sbjct: 2207 DNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIE 2266
Query: 1694 SLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRISN 1751
K +A L LF +P L++ R ++ + T++ IL +L
Sbjct: 2267 RRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTE- 2321
Query: 1752 YFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENP 1811
K VP + + + F+F+ W+ GG+ D ++ D +
Sbjct: 2322 --KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF---------- 2361
Query: 1812 VPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDII 1865
KW F +G ++DY + K +++ W + + + L D + +Q +
Sbjct: 2362 -----SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQASL 2414
Query: 1866 VPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSAR 1925
V T +TIR + MDL + + P++ VG GTGKSV + DKL L D Y + +
Sbjct: 2415 VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFNFY 2473
Query: 1926 TSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDC 1985
T++ +Q ++ L+K+ +GPP KK + FIDDMNMP ++KYG P L+RQ D
Sbjct: 2474 TTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDH 2533
Query: 1986 GHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRI 2042
HWY D K+TL DI + +A M P G + R RHF + +++ E + I
Sbjct: 2534 RHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTI 2589
Query: 2043 FSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVI 2102
+++I+ +L I +Q+V + ++++ LPT K HY FNLRD S +
Sbjct: 2590 YNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIF 2649
Query: 2103 RGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE---- 2158
+G L + + ++RL++HE RV+ D+++++ D+ L ++T K F +
Sbjct: 2650 QGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDE 2709
Query: 2159 ---SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQC 2215
+ +IF H + D Y+ + ++ + ++
Sbjct: 2710 LLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLVDV 2746
Query: 2216 LDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAK 2275
LD YN+ + MNLV+F + H+ RI R+L+ GNALLVG+GGSG+QSL+RLA ++
Sbjct: 2747 LDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISG 2805
Query: 2276 MHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306
+ +FQ + K YG+ + + D+ + +I V N
Sbjct: 2806 LDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2837
Score = 427 bits (1098), Expect = e-119
Identities = 273/824 (33%), Positives = 424/824 (51%), Gaps = 72/824 (8%)
Query: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375
+++R+ L D TY++Y R LFE+DKL+F + +L +KE+ EL FLL
Sbjct: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3742
Query: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435
K+ +P +LQ + W I SE F+ L W+++ +S+ P FP
Sbjct: 3743 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3801
Query: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495
KN LQK+ ++RCLRPD++T AI N+V +K+G KFVE + +KSY +S+ +
Sbjct: 3802 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3860
Query: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
+ F+LSPG DP+ + ++ K +SLGQGQ +A + A E+G WV L
Sbjct: 3861 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3920
Query: 2554 Q--------NCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQ 2600
Q N HL W+ L+K E +++ + + +R+++++ P+ P IL+
Sbjct: 3921 QVRGGQHCRNIHLVARWLGTLDKKLEHYSTGS-HEDYRVFISAEPAPSPETHIIPQGILE 3979
Query: 2601 NGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERK 2660
N +K+TNEPPTG+ NL ++ + + + C KE+ ++ +LF +C+FHA+V ER+
Sbjct: 3980 NAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERR 4035
Query: 2661 KFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRR 2720
KFG GWN Y FN DL ISI L ++ +P++ + YL GE YGG +TDDWDRR
Sbjct: 4036 KFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR 4095
Query: 2721 LLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHEN 2780
L T LA++ ++E +P + PP Y+ Y E+I + + P ++GLH N
Sbjct: 4096 LCRTYLAEYIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPN 4152
Query: 2781 VDISKDLQQTKTLFESLLLTQGGSKQTGA---------SGSTDQILLE------------ 2819
+I ++ LF ++L Q +GA +GS + E
Sbjct: 4153 AEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGG 4212
Query: 2820 ----------ITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRN 2869
+ DIL K+P F++ + K + V QE ER N L +R
Sbjct: 4213 CPGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRR 4270
Query: 2870 TLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFL 2929
+L++L +KG + + + +E LS +L VP+ W R+YPS+ L ++ D L R+ L
Sbjct: 4271 SLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIREL 4330
Query: 2930 QDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS-- 2986
+ W P WL+GFF Q+FLT MQ+ ARK P+D + EV + D +
Sbjct: 4331 EAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAP 4390
Query: 2987 PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLY 3046
P +G Y++GL+++GARWD ++G++AE K L MP+I+IK R+ + Y CP+Y
Sbjct: 4391 PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
Query: 3047 KTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3090
KT R T +V LKT + WI VALL Q+
Sbjct: 4451 KTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 924 bits (2389), Expect = 0.0
Identities = 627/2008 (31%), Positives = 1031/2008 (51%), Gaps = 136/2008 (6%)
Query: 388 VLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFI 447
+L +V++L+ A H L+ +K+ + E + ++ F + + E I
Sbjct: 988 LLSSSVNSLRKAAHEALQDFQKYKTLWTEDRD--------VKVKEFLANNPSLTEIRSEI 1039
Query: 448 EKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECIC 507
+ + EI L I + L E +K L+ +AKA+ +L + +Y+K+ +
Sbjct: 1040 LHYATFEQEIDELKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMI 1099
Query: 508 SEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL----DVF 563
+ I E+ K+ ++ D+ +E + E+ + + + +Y + +V
Sbjct: 1100 A---FINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVE 1156
Query: 564 LFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRM 623
+ +E A++ + + + ++L++ K N L+ +E +
Sbjct: 1157 VTKEESEAVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSN--------LLESVEVFREDV 1208
Query: 624 EEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKE-------EELFKWELTKYPEL 676
F E ELE ++ R+Q + + + ++ E+LF +T Y L
Sbjct: 1209 INFAEAYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVL 1268
Query: 677 DKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKF 733
K + + QK + S + + + D++ E + A++ EF R++ K LK
Sbjct: 1269 HKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKD 1328
Query: 734 FQT--KLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVG--YD 789
+Q LKK + + ++ + K M+ RHW +ISE+ G +D
Sbjct: 1329 WQAFLDLKKRIDDFSESCPLLEMMTNKA--------------MKQRHWDRISELTGTPFD 1374
Query: 790 LTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRD 849
+ DS LR +++ L + + E I A KE +E + +I W + + ++
Sbjct: 1375 VESDS-FCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKG 1433
Query: 850 TGVCILSSVD--EIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLK 907
G +L + EI +++D ++ ++ + + PF+ I+ W +L + I+EWL
Sbjct: 1434 KGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLV 1493
Query: 908 VQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVL-AATSLTGLLE 966
VQ W+YLE +F DI +Q+P+E ++FQ +D+ W IM+ ++P V+ + +
Sbjct: 1494 VQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQ 1553
Query: 967 KLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFE 1026
L + +E LE K L YLEKKRL FPRFFF+S+ +LEIL + D +QPHL +
Sbjct: 1554 LLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSD 1613
Query: 1027 GIAKLEF-LPNLD-IKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVI 1084
I ++ F + D I A+ S EGE+ I L ++ A+G VE WL+ + + + S+H++I
Sbjct: 1614 NINEVTFHAKDYDRIMAVISREGEK---IVLDNSVMAKGPVEIWLLDLLKMQMSSLHNII 1670
Query: 1085 AAARLAYPESARR--DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQNQ- 1141
+A +S + ++ +P QV L QM WT +++E + + K ++ NQ
Sbjct: 1671 RSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDRK--IMQVTNQK 1728
Query: 1142 ----LNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRY 1197
LN ++ LSK R L+TI VH RD+ D++KM + TDF WL Q R+
Sbjct: 1729 FLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRF 1788
Query: 1198 YWENE--NARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPA 1255
Y++ + V I + + Y E+LG + RLVITPLTDRCY TL A +N+GGAP GPA
Sbjct: 1789 YFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPA 1848
Query: 1256 GTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVL 1315
GTGKTETTKD+ + L VVFNCSD +D+ +G+ FKGLA SG+W CFDEFNRIEL VL
Sbjct: 1849 GTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVL 1908
Query: 1316 SVVAQQILCIQRAIQQKLVVFVF-EGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFR 1374
SV AQQI + A +++ F+F +G + LNP + +TMNPGYAGR ELP+NLK+ FR
Sbjct: 1909 SVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFR 1968
Query: 1375 TVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVL 1434
TVAMMVP+ +I + L S GFL L+ K + Y+LC EQL+ Q HYD+G+R + +VL
Sbjct: 1969 TVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVL 2028
Query: 1435 VAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEF 1494
G+ K P ++E +++R ++D+N K + D PLF + +DLFPG++L Y E
Sbjct: 2029 RTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAEL 2088
Query: 1495 LECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLM 1554
+ L + K++Q YE +VRHG M +G + KT V+ +L T
Sbjct: 2089 QNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQT-- 2146
Query: 1555 NEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWV 1614
E G E +NPK+IT Q+FG+ D +++WTDGI + +R+ ++ + ++
Sbjct: 2147 -ECGRPHRE----MRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFL 2201
Query: 1615 VFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGM 1674
+ DGP+D +WIE++N+VLDDNK L L +G+ I M+P L+FE ++ ASPATVSR GM
Sbjct: 2202 ILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGM 2261
Query: 1675 IYLEPSQLGWEPLVSSWL---NSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNY 1731
+Y+ S L W P++ +WL + + + Y+ + + ++ +LN +++L + NY
Sbjct: 2262 VYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEKVFEDTYTYM-KLNLNPKMQLLECNY 2320
Query: 1732 LYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDG 1791
+ ++ +L+ LI + V H F+F L+WS+G + +
Sbjct: 2321 IVQSL--NLLEGLIPSKEEGGVSCVE------------HLHKLFVFGLMWSLGALLELES 2366
Query: 1792 RRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYD-YMYELKNKGRWVHWNELIK 1850
R + F+R K + P KG Y + + + G W HWN+ ++
Sbjct: 2367 REKLEAFLR-------------QHESKLDLPEIPKGSNQTMYEFYVTDYGDWEHWNKKLQ 2413
Query: 1851 NTNLGDKQI-KIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNH 1909
I + I+VP +D IR FL+D K +L G GT K+V VK L +
Sbjct: 2414 PYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKY 2473
Query: 1910 LEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEK 1969
+ + +N S+ T Q I + +DKR +GPP G+K +FIDD+NMP + +
Sbjct: 2474 -DPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINE 2532
Query: 1970 YGAQPPIELLRQFFDCGHWYDL-KDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNI 2028
+G Q E++RQ + Y L K T+VD++LIAAM PGGGRN + R R F +
Sbjct: 2533 WGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTV 2592
Query: 2029 CSINSFSDETMVRIFSSI-VAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPT 2087
+ S+ ++ +IF I ++ F P+ + +V+ +++ + +LPTP+
Sbjct: 2593 FNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPS 2652
Query: 2088 KSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWL-FQ 2146
K HY FNLRD SR+ +G L I+ + A+ T++ LF HE RV DR I +D +W
Sbjct: 2653 KFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAH 2712
Query: 2147 LTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNL--MFGDYMNPDLEGDDRVYIEIPN 2204
LT+ V ++ ++ I P + LR + GD + ++Y +P+
Sbjct: 2713 LTRAVEENIGSDAASCILPE------PYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPS 2766
Query: 2205 IHHFSDVVDQCLDEYNQTHK-TRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGR 2263
++ + ++N+ + T ++LV F+ + HL +I R+++ S GNALLVG+GGSG+
Sbjct: 2767 FDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGK 2826
Query: 2264 QSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVP------VTNRIVDNKSKILE 2317
QSL+RLA+ +A IFQ +++SY + +D+K+ V +T D++ K E
Sbjct: 2827 QSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKD-E 2885
Query: 2318 KRLRYLNDHFTYNLYCNICRSLFEKDKL 2345
L YLN+ + N LF +D++
Sbjct: 2886 AFLEYLNNLLSSGEISN----LFARDEM 2909
Score = 451 bits (1160), Expect = e-126
Identities = 262/794 (32%), Positives = 419/794 (52%), Gaps = 44/794 (5%)
Query: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
KS + +KR+ + ++ TY ++ R L+E K LF L+ + L R ++++E L+
Sbjct: 3725 KSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALI 3784
Query: 2372 TGGVSLKSAEKNPDP-TWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPH 2430
GG +L P P W+ D +W + S+ P F + + W+ +D P
Sbjct: 3785 KGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPE 3844
Query: 2431 NAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDS 2490
P + +L+ K++++R PD+ Y+ D L +K+ EP +L K++ +S
Sbjct: 3845 EEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEES 3904
Query: 2491 NCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTW 2550
+ PLI LS G+DP + A + + + IS+GQGQ A K+I+ ++++G W
Sbjct: 3905 DTRTPLICFLSMGSDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGW 3961
Query: 2551 VCLQNCHLAVSWM-PMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEP 2609
V LQNCHL + +M +LE + T+E + SFR+W+T+ P +FP+T+LQ +K TNEP
Sbjct: 3962 VLLQNCHLGLEFMEELLETL---ITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEP 4018
Query: 2610 PTGLRLNLLQSY------LTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFG 2663
P G+R L +++ L D + P W+ +L+ V F H+ VQER+KFG
Sbjct: 4019 PQGVRAGLKRTFAGINQDLLDISNLP-----------MWKPMLYTVAFLHSTVQERRKFG 4067
Query: 2664 PLGWNIPYGFNESDLRISIRQLQLFINEYDT---IPFEAISYLTGECNYGGRVTDDWDRR 2720
PLGWNIPY FN +D S++ +Q ++E D + + + Y+ GE YGGRVTDD+D+R
Sbjct: 4068 PLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKR 4127
Query: 2721 LLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHEN 2780
LL +++ + E P + F Y P T + Y E+I+ LP +PE+FGLH N
Sbjct: 4128 LLNCFARVWFSEKMFE-PSFCFYT--GYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPN 4184
Query: 2781 VDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDF-DIEMALR 2839
DI+ + E++ Q G + + I+ +++D+L+KLP D+ E+ R
Sbjct: 4185 ADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSR 4244
Query: 2840 KYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGK 2899
+ + SMN L QE++R +I +R++L DL+ AI+G ++M L ++ +
Sbjct: 4245 LIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDAR 4304
Query: 2900 VPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQN 2959
+P++W + S+ S LG + T+ L R W G+P VFW++GFF Q FLT Q
Sbjct: 4305 IPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQE 4363
Query: 2960 YARKYT-TPIDLLGYEFEVIPSDTSD--TSPEDGVYIHGLYLDGARWDRESGLLAEQYPK 3016
R + +D + EV+ + + P +GVYI+GLY+DGA WDR +G L E PK
Sbjct: 4364 VTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPK 4423
Query: 3017 LLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPT 3076
+LF +P++ I + YVCP+YK R F+ + L+T
Sbjct: 4424 VLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRT--------DLTFITVVYLRTVLSP 4475
Query: 3077 RHWIKRGVALLCQL 3090
HWI RGVALLC +
Sbjct: 4476 DHWILRGVALLCDI 4489
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 916 bits (2367), Expect = 0.0
Identities = 656/2119 (30%), Positives = 1039/2119 (49%), Gaps = 170/2119 (8%)
Query: 320 QQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSG------ 373
Q LPIF+ +T + P +D++ + VE I + V+ S L
Sbjct: 1004 QNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQE 1063
Query: 374 -------TSTPVNLDTELPEHVLHWAVDTLK-AAVHRNLEGARKHYETYV---------- 415
++ + D E+ E+ L DTL+ A+V+ + K+Y V
Sbjct: 1064 RKMAALQSNEDSDSDVEMGENELQ---DTLEIASVNLPIPVQTKNYYKNVSENKEIVKLV 1120
Query: 416 ---------------------EKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLA 454
++YN + E I+TF T+ E+ I F +L
Sbjct: 1121 SVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLE 1180
Query: 455 SEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIK 514
EI P+++ + L DLK LT + KA+ ++ KYR E E I F I+
Sbjct: 1181 QEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENI---FMLIE 1237
Query: 515 EHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL----DVFLFPQEDL 570
E K+ +++ D+ + + + E++ + Q + SY L + + +E
Sbjct: 1238 EFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEID 1297
Query: 571 ALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFA 630
++ W + + + ++L+ K+ EL++ E + + + + A
Sbjct: 1298 KVDTLHYAWEKLLARAGEVQNKLVSLQPSFKK-ELISAVEVFLQDCHQFYLDYDLNGPMA 1356
Query: 631 ELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFF 690
+ Q+ + Q + EELF T+YP+L ++K + QK +
Sbjct: 1357 SGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIY 1416
Query: 691 NFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQT--KLKKELQEK 745
+ + D + ++N E + ++ EF R++ + LK +Q LKK + +
Sbjct: 1417 TLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDF 1476
Query: 746 RKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDL-TPDSGTTLRKVLKL 804
+ K M RHW++I+ + G+ L + LR +++
Sbjct: 1477 SECCPLLEYMASKA--------------MMERHWERITTLTGHSLDVGNESFKLRNIMEA 1522
Query: 805 NLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCIL--SSVDEIQ 862
L Y E+ E I A KE +E+ + +I W++ F ++ G +L S EI
Sbjct: 1523 PLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEII 1582
Query: 863 AILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSE 922
A ++D ++ ++ + + PF+ +I+ W L + I+ W+ VQ W+YLE +F
Sbjct: 1583 ANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG 1642
Query: 923 DIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVL-AATSLTGLLEKLQNCNELLEKIMKG 981
DI +Q+P+E ++F +D+ W IM + P V+ L + L + + LE K
Sbjct: 1643 DIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKS 1702
Query: 982 LNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNL--DI 1039
L YLEKKRL FPRFFF+S+ +LEIL + D +Q HL F+ I ++F + I
Sbjct: 1703 LTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRI 1762
Query: 1040 KAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVI--AAARLAYPESARR 1097
++ S EGE +EL + A G VE WL + + S+H VI AAA +
Sbjct: 1763 LSISSQEGETIELDKPVM---AEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLT 1819
Query: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQ---NQLNEIVELVRGKLS 1154
+++ +P QV L QM WT +++E + K K Q LN ++++ LS
Sbjct: 1820 EFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLS 1879
Query: 1155 KQTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVK 1214
R L+TI VH RD+ D+ M + DF WL Q R+Y+ ++ ++ I +V
Sbjct: 1880 STERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVA 1939
Query: 1215 YAY--EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAV 1272
+ Y E+LG + RLVITPLTDRCY TL A +++GGAP GPAGTGKTETTKD+ + L
Sbjct: 1940 FIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGK 1999
Query: 1273 QCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQK 1332
VVFNCSD +D+ +G+ FKGLA SG+W CFDEFNRI+L VLSV AQQI I ++
Sbjct: 2000 YVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEH 2059
Query: 1333 LVVFVF-EGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISL 1391
F+F +G + +NP + +TMNPGYAGR ELP+NLK+ FR+VAMMVP+ +I + L
Sbjct: 2060 KKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKL 2119
Query: 1392 YSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDI 1451
S GF++ L+ K Y+LC EQLS Q HYD+G+R + +VL G K P + E
Sbjct: 2120 ASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTEST 2179
Query: 1452 LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECA----HEACNVHNL 1507
+++R ++D+N K + D PLF + DLFP I L +A Y E LE A E + N
Sbjct: 2180 IVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPE-LEAAISRQVEEAGLINH 2238
Query: 1508 QPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIY 1567
P K K+IQ +E VRHG M +G A KT +H L + M + G E
Sbjct: 2239 PPWKL---KVIQLFETQRVRHGMMTLGPSGAGKTTCIHTL---MRAMTDCGKPHRE---- 2288
Query: 1568 RTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIES 1627
+NPK+IT Q+FG+ D +++WTDGI + +R+ ++ + W++ DGP+D +WIE+
Sbjct: 2289 MRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIEN 2348
Query: 1628 MNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPL 1687
+N+VLDDNK L L +G+ I M+P +IFE ++ ASPATVSR GM+++ S L W P+
Sbjct: 2349 LNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPI 2408
Query: 1688 VSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNYLYTTIVSKILKILITF 1747
+ +L P+ +LR L+ P R + L Y + + +IT
Sbjct: 2409 LEGFLKKR-----SPQEAEILRQLYTESFPDL--YRFCIQNLEYKMEVLEA----FVITQ 2457
Query: 1748 RISNYFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKD 1807
I+ +PLK Q + H F+F+L+WS G + + DGRR + ++R G
Sbjct: 2458 SINMLQGLIPLKEQGGEVS-QAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTL 2516
Query: 1808 DENPVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKN-TNLGDKQIKIQDIIV 1866
+ +P G + FD Y + G W HWN + D + I+V
Sbjct: 2517 E---LPPPAGPGDTAFD---------YYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILV 2564
Query: 1867 PTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSART 1926
P +D +R FL+ K +L +G GT K+V +K M+ + + + +N S+ T
Sbjct: 2565 PNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKG-FMSKYDPECHMIKSLNFSSAT 2623
Query: 1927 SANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCG 1986
+ Q I + +DKR +GPP GKK +FIDD+NMP + ++G Q E++RQ +
Sbjct: 2624 TPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQN 2683
Query: 1987 HWYDLKDTSKIT-LVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSS 2045
+Y+L+ + T +VDI+ +AAM PGGGRN + R R F+I + S+ ++ +IF
Sbjct: 2684 GFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGV 2743
Query: 2046 I-VAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRG 2104
I V Y F E ++V T +++ + +LPTP K HY FNLRD SRV +G
Sbjct: 2744 IGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQG 2803
Query: 2105 CLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE------ 2158
L + + + +++L+ HE RV DR D W + +++++ F E
Sbjct: 2804 MLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLV 2863
Query: 2159 -----SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVD 2213
++ F + A T E+ D P ++Y I + H + ++
Sbjct: 2864 DCGIDTYFVDFLRDAPEAAGETSEE------ADAETP------KIYEPIESFSHLKERLN 2911
Query: 2214 QCLDEYNQTHK-TRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATS 2272
L YN++ + M++V F + HL +I RV++ GNALLVG+GGSG+QSLTRLA+
Sbjct: 2912 MFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASF 2971
Query: 2273 MAKMHIFQPEISKSYGMNEWREDMKSFIAVP------VTNRIVDNKSKILEKRLRYLNDH 2326
+A FQ +++SY + ED+K +T DN+ K E L Y+N+
Sbjct: 2972 IAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKD-ESFLEYMNNV 3030
Query: 2327 FTYNLYCNICRSLFEKDKL 2345
+ N LF +D++
Sbjct: 3031 LSSGEVSN----LFARDEI 3045
Score = 446 bits (1146), Expect = e-124
Identities = 256/790 (32%), Positives = 415/790 (52%), Gaps = 37/790 (4%)
Query: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371
KS I KR+ + +H TY +Y R L+E+ K LF+ LL + + R ++++E + L+
Sbjct: 3860 KSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLI 3919
Query: 2372 TGGVSLKSAEKNPDPT-WLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPH 2430
GG SL P P+ W+ D +W + S+ F + + W+ +D + P
Sbjct: 3920 KGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPE 3979
Query: 2431 NAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDS 2490
P DK+L+ ++++++R PD+ Y+ D +G+K+ E DL K++ +S
Sbjct: 3980 EEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEES 4039
Query: 2491 NCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTW 2550
+ PLI +LS G+DP S++ + + + +S+GQGQ A K+++ + G W
Sbjct: 4040 DPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQEVHARKLLQQTMANGGW 4096
Query: 2551 VCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPP 2610
LQNCHL + +M L I +E + +FRLW+T+ +FP+T+LQ +K N+PP
Sbjct: 4097 ALLQNCHLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPP 4154
Query: 2611 TGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIP 2670
GLR L ++Y + G + W+ +L+ V F H+ VQER+KFG LGWNIP
Sbjct: 4155 QGLRAGLKRTYSGVSQDLLDVSSGSQ-----WKPMLYAVAFLHSTVQERRKFGALGWNIP 4209
Query: 2671 YGFNESDLRISIRQLQLFINEYDT---IPFEAISYLTGECNYGGRVTDDWDRRLLLTMLA 2727
Y FN++D +++ +Q +++ D + + I Y+ GE YGGRVTDD+D+RLL T
Sbjct: 4210 YEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNT--- 4266
Query: 2728 DFYNLYIVEN---PHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDIS 2784
F ++ EN P + F Y P T ++Y+++I+ LP PE+FGLH N DI+
Sbjct: 4267 -FAKVWFSENMFGPDFSFYQ--GYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADIT 4323
Query: 2785 KDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDF-DIEMALRKYPV 2843
+ K + +++L Q G + + ++ + D+L KLP D+ E+ R +
Sbjct: 4324 YQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKM 4383
Query: 2844 RYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEI 2903
+ MN L QE++R ++ +R+TL +L+ AI G ++M L + ++P
Sbjct: 4384 GPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAW 4443
Query: 2904 WAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARK 2963
W K S+ S LG + T+ + R + W +G+P FW++GFF Q FLT Q R
Sbjct: 4444 WKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRA 4502
Query: 2964 ---YTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFD 3020
+ +L E D P +GVY++GLYL+GA WD+ + L E PK+LF+
Sbjct: 4503 NKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFE 4562
Query: 3021 LMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWI 3080
LMP+I I + + + Y CP+YK R N++ A+ L+T Q HW+
Sbjct: 4563 LMPVIRIY-AENNTLRDPRFYSCPIYKKPVRT--------DLNYIAAVDLRTAQTPEHWV 4613
Query: 3081 KRGVALLCQL 3090
RGVALLC +
Sbjct: 4614 LRGVALLCDV 4623
>gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]
Length = 457
Score = 898 bits (2320), Expect = 0.0
Identities = 445/448 (99%), Positives = 447/448 (99%)
Query: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG
Sbjct: 1 MSDANKAAIAAEKEALNLKLPPIVHLPENIGVDTPTQSKLLKYRRSKEQQQKINQLVIDG 60
Query: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML
Sbjct: 61 AKRNLDRTLGKRTPLLPPPDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHML 120
Query: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP
Sbjct: 121 RLIPESLKEGKEREELLESLINEVSSDFENSMKRYLVQSVLVKPPVKSLEDEGGPLPESP 180
Query: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID
Sbjct: 181 VGLDYSNPWHSSYVQARNQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPID 240
Query: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL
Sbjct: 241 CESLKTDLSIQTRNAEEKIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQL 300
Query: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA
Sbjct: 301 KDLLRRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA 360
Query: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW
Sbjct: 361 LQNVQTIPSWLSGTSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNW 420
Query: 421 LLDGTAVENIETFQTEDHTFDEYTEFIE 448
LLDGTAVENIETFQTEDHTFDEYTE ++
Sbjct: 421 LLDGTAVENIETFQTEDHTFDEYTEELD 448
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 717 bits (1851), Expect = 0.0
Identities = 492/1640 (30%), Positives = 807/1640 (49%), Gaps = 180/1640 (10%)
Query: 774 MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
++ RHWKQ+ + + + S TL ++ ++L + + A E +LE+ + +
Sbjct: 1408 LKDRHWKQLMKRLHVNWVV-SELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQI 1466
Query: 834 IGTWEDIAFHISLYRDTGVC-ILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWE 892
W + + L C ++ D++ + + I M+ SP+ K FE + +WE
Sbjct: 1467 REVWN--TYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWE 1524
Query: 893 DRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIMQQMPEEGRQFQTVDRHWRDIMKFCAK 951
D+L RI D W+ VQ +W+YLE IF S DI +P E ++FQ++ + +MK +K
Sbjct: 1525 DKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 1584
Query: 952 DPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSET 1011
P V+ ++ G+ L+ +LL KI K L YLE++R FPRF+F+ ++++LEI+ +
Sbjct: 1585 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNS 1644
Query: 1012 KDPLRVQPHLKKCFEGIAKLEFLP-NLDIKAMYSSEGERVELIALISTSAARGAVEKWLI 1070
K+ ++Q H KK F G++ + N + + S EGE V +S + + +WL
Sbjct: 1645 KNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINEWLT 1703
Query: 1071 QVED--------LMLRSVHDV-IAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQ 1121
VE L+ SV +V I + + W+ ++ Q+V+ +Q+ W+ +
Sbjct: 1704 LVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVE 1763
Query: 1122 EVIS-----GGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVM 1176
+S G L ++ LN + + V + R L L+T VH RDV
Sbjct: 1764 TALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTR 1823
Query: 1177 DMIKMGVSHDTDFLWLAQLRYYWENENARV------RIINCNVKYAYEYLGNSPRLVITP 1230
+IK + + F WL+Q+R+Y++ + V ++ N Y +EYLG +LV TP
Sbjct: 1824 SLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTP 1883
Query: 1231 LTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGK 1290
LTDRCY T+ A LGG+P GPAGTGKTE+ K L L +VFNC + D+ AMG+
Sbjct: 1884 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 1943
Query: 1291 FFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL----------VVFVFEG 1340
F GL GAW CFDEFNR+E +LS V+QQ+ CIQ A+++ +
Sbjct: 1944 IFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLN 2003
Query: 1341 TELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAR 1400
++K++P+ + ITMNPGYAGRS LPDNLK LFR++AM P+ LIA++ LYS GF A
Sbjct: 2004 KQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAE 2063
Query: 1401 PLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL------KLKYPNEN------ 1448
L+ KIV ++LC EQLSSQ HYD+G+RA+K+VLV+AGN+ K+K E
Sbjct: 2064 VLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVD 2123
Query: 1449 ---------EDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAH 1499
E +L++S+ + PK ++ DIPL + SD+FPG++ + E
Sbjct: 2124 EGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELK 2183
Query: 1500 EACNVHNL------QPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTL 1553
+ C L + ++EK++Q Y++ + HG M+VG + K+ VL L
Sbjct: 2184 KVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALER 2243
Query: 1554 MNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALS---ETPD 1610
+ E + + ++PK+I+ L+G DP + EWTDG+ + R+ S E
Sbjct: 2244 L------EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQK 2297
Query: 1611 RKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVS 1670
R+W+VFDG +D W+E++N+VLDDNK L L +GE + + P + ++FE DL A+ ATVS
Sbjct: 2298 RQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVS 2357
Query: 1671 RCGMIYLEPSQLGWEPLVSSWLNSLKG-PLCEPEYQALLR-------GLFAWLIPPSLNQ 1722
RCGM++ L + + +++L L+ PL E E +A R G A P L
Sbjct: 2358 RCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEA--ASPMLQI 2415
Query: 1723 RVELFQLNYLYTTIVSKILKIL-ITFRISNYFKYVPLKTQCTFIKFFLHQQAC------- 1774
+ + + Y T + K L F++ + L+ C F + QAC
Sbjct: 2416 QRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLR--CLGSLFSMLHQACRNVAQYN 2473
Query: 1775 --------------------FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPD 1814
+++++WS+ G R +IR I P+P
Sbjct: 2474 ANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRI-----TTVPLPT 2528
Query: 1815 SVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRY 1874
+ P + YE+ G W W + + ++ D++VPT+DT+R+
Sbjct: 2529 AP---NIPIID--------YEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRH 2577
Query: 1875 TFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNI 1934
L+ + KPL+ GP G+GK++ + L + + +N S+ T+ +
Sbjct: 2578 EALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDME---VVGLNFSSATTPELLLKT 2634
Query: 1935 IMARLDKRR--KGVFGPP--MGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYD 1990
+ RR GV P +GK ++F D++N+P ++KYG Q I +RQ + G +Y
Sbjct: 2635 FDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYR 2694
Query: 1991 LKDTSKITLVDIELIAAMGPP-GGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAF 2049
D + + L I+ + A PP GR P++ R +RH + ++ ++ +I+ +
Sbjct: 2695 TSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRA 2754
Query: 2050 YLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIE 2109
LR P + +E Y S E T+ HY ++ R+ +R +RG
Sbjct: 2755 MLR---LIPSLRTYAEPLTAAMVEFYTMSQER-FTQDTQPHYIYSPREMTRWVRGIFEAL 2810
Query: 2110 RD-AVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE-------SFH 2161
R +IR++ HE LR+F DRL+ D++RRW + TV HF S
Sbjct: 2811 RPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRP 2870
Query: 2162 SIFSH-LRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYN 2220
++S+ L K PV +E+LR DY+ L+ +++P
Sbjct: 2871 ILYSNWLSKDYIPVDQEELR-----DYVKARLKVFYEEELDVP----------------- 2908
Query: 2221 QTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQ 2280
LV+F VL+H+ RI R+ +Q G+ LL+G+ G+G+ +L+R M + ++Q
Sbjct: 2909 --------LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQ 2960
Query: 2281 PEISKSYGMNEWREDMKSFI 2300
++ + Y ++ ED+++ +
Sbjct: 2961 IKVHRKYTGEDFDEDLRTVL 2980
Score = 201 bits (511), Expect = 9e-51
Identities = 199/818 (24%), Positives = 348/818 (42%), Gaps = 74/818 (9%)
Query: 2318 KRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARK-EIEYQ-ELMFLLTGGV 2375
+RL + + + R + +D + F+ LL L E Y E L G
Sbjct: 3854 QRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNE 3913
Query: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGL--RQHFCEHIYEWREIYDSKE--PHN 2431
+ SA P L + E + R S PAF+ L + E W + ++ P+
Sbjct: 3914 IVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYL 3973
Query: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVE--PPPFDLTKSY-L 2488
P + ++++++ RPD++ +V+ LG+ F+ P DLT
Sbjct: 3974 WSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGT 4033
Query: 2489 DSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQG-PIAAKMIKAAIEE 2547
+ P++ PG D + A +++ + +I++G +G A K I A++
Sbjct: 4034 EVKPNTPVLMCSVPGYDASGHVEDLAAEQN---TQITSIAIGSAEGFNQADKAINTAVKS 4090
Query: 2548 GTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTN 2607
G WV L+N HLA W+ LEK C FRL+LT + K PV +L+ G
Sbjct: 4091 GRWVMLKNVHLAPGWLMQLEKKLHSLQPHAC---FRLFLTMEINPKVPVNLLRAGRIFVF 4147
Query: 2608 EPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGW 2667
EPP G++ N+L+++ + PVS + C+ +L F + +FHA++QER ++ PLGW
Sbjct: 4148 EPPPGVKANMLRTFSSIPVS-----RICKSPNER-ARLYFLLAWFHAIIQERLRYAPLGW 4201
Query: 2668 NIPYGFNESDLRISIRQLQLFINEY---------DTIPFEAISYLTGECNYGGRVTDDWD 2718
+ Y F ESDLR + + ++++ D IP+ A+ L + YGGRV +++D
Sbjct: 4202 SKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFD 4261
Query: 2719 RRLLLTMLADFYNLYIVENPH---YKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIF 2775
+RLL T L + ++ K + P E+++++++ LP TQ P
Sbjct: 4262 QRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWL 4321
Query: 2776 GLHENVD-----------ISKDLQQTKTLFESLLLTQGGSKQTGASGSTD------QILL 2818
GL N + ISK L+ E L K+T ++D + L
Sbjct: 4322 GLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLH 4381
Query: 2819 EITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAI 2878
+ L+ +P L++ ++ + +E++ L+ +R L D+ +
Sbjct: 4382 TTASNWLHLIPQTLS---HLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVC 4438
Query: 2879 KGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSG-- 2936
+G + L L L+ G +P W+ + P+ + +++DF R+ LQ+ +
Sbjct: 4439 EGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAAS 4498
Query: 2937 ------KPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTSPEDG 2990
K L G F +A++T Q A+ + ++ L E V S + T
Sbjct: 4499 GGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGA-TLDACS 4557
Query: 2991 VYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSE 3050
+ GL L GA + L+ L L + W+K T + K+ P+Y
Sbjct: 4558 FGVTGLKLQGATCNNNKLSLSNAISTAL-PLTQLRWVKQTNTEK--KASVVTLPVY---- 4610
Query: 3051 RKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLC 3088
L+ T F + + T + R + +RGVA+LC
Sbjct: 4611 ----LNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 690 bits (1780), Expect = 0.0
Identities = 470/1413 (33%), Positives = 689/1413 (48%), Gaps = 231/1413 (16%)
Query: 675 ELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFF 734
E+ ++ ++ +K + +W+R+ W N DVE R + K +
Sbjct: 988 EISDIEGDLTLRKKLWEAQEEWKRASWEWR-------NSSLQSIDVESVQRNVSKLMHII 1040
Query: 735 QTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDS 794
L+K L + + + E +E P A C ++ RHW+ + EI+G + D
Sbjct: 1041 SV-LEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPC-LKPRHWEALQEIIGKSVPLDK 1098
Query: 795 GTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWED-----IAFHISLYRD 849
+ +L L + Y + +S A+ E +LEK + +I W I H +Y
Sbjct: 1099 NCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIY-- 1156
Query: 850 TGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQ 909
+ I+ S+D+I A L++ + T++GSP I P + + W+ L T++EW+ Q
Sbjct: 1157 -SIFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQ 1215
Query: 910 AQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQ 969
WLYLEP+F S +I +Q+P E F V W+ IM L T+ G+LE LQ
Sbjct: 1216 RNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQ 1275
Query: 970 NCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIA 1029
NCN LE I K L YLE KRL FPRF+FLSN E+L+IL+++++P VQPHL KCFE I
Sbjct: 1276 NCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIK 1335
Query: 1030 KL----EFLPNLDIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIA 1085
+L + + +K + S+EGE + L I R AVE+WL+ VE +S+ DV+
Sbjct: 1336 QLLIWKQDIGPPAVKMLISAEGEGLVLPKKIRV---RSAVEQWLVNVE----KSMFDVLK 1388
Query: 1086 AARLAYPESARRDWVREWPGQVVLCISQ-MFWTSETQEVISG-GTEGLKKYYKELQNQLN 1143
R Y ++L SQ MF+ + +S E L+K + L L
Sbjct: 1389 KERYIY-------------NIILLFQSQIMFYNDCVKSFVSSYSREKLEKVHAGLMCHLE 1435
Query: 1144 EIVELVRGKLSK-QTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENE 1202
E+ +LV S +T+ LGAL+ + VH RD+V++++ + + DF W L+Y W NE
Sbjct: 1436 EVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKW-NE 1494
Query: 1203 NARVRII---NCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGK 1259
++ + N + Y YEYLG + RLVITPLTDRC+ TL+ A +LNLGG P GPAGTGK
Sbjct: 1495 KQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGK 1554
Query: 1260 TETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVA 1319
TET KDLAK+L CVVFNC + LDY + KFF GL SGAW+CFDEFN I+LEVLSV+A
Sbjct: 1555 TETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIA 1614
Query: 1320 QQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMM 1379
QIL I+ A FV EG E+++N +C V ITMNP Y G ELPDNLK LFR VAMM
Sbjct: 1615 SQILTIKAAKDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMM 1674
Query: 1380 VPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGN 1439
VP+Y +IAEI L+S+GF +A LS K+ Y L +QLS Q HY++G+R++K VL+ AG
Sbjct: 1675 VPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGT 1734
Query: 1440 LKLKY---PNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLE 1496
K ++ +E ++++ +I++ + PK D+PLF I D+FP + + + + +
Sbjct: 1735 KKREFKCLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEK 1794
Query: 1497 CAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNE 1556
+ A LQ EKIIQ Y + V G MLVG KT V +L LTL+
Sbjct: 1795 VIYTATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPI 1854
Query: 1557 HGY-------------GEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREF 1603
+ + KV +NPK +T+ +L+GQ DP + EWTDG+++ T R +
Sbjct: 1855 ADFLSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSY 1914
Query: 1604 ALSETP----------------------------------------------------DR 1611
TP D
Sbjct: 1915 VYFNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDW 1974
Query: 1612 KWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSR 1671
+W++ DGP+DT W+E++N+VLDD + LCL + E I ++ ++ +IFE +LSQASPATVSR
Sbjct: 1975 QWIILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSR 2034
Query: 1672 CGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIPPSLNQRVELFQLNY 1731
C M+Y++P LGWEP V SWL + + L ++I S+ ++ +
Sbjct: 2035 CAMVYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCL-----EFMIKNSVTDGLQFIRNRQ 2089
Query: 1732 LY-------TTIVSKILKILITF---------------------------RISNYFKYVP 1757
+ T+V + +IL F R S FK +
Sbjct: 2090 KFQPYPMEDITVVITLCRILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIE 2149
Query: 1758 LKTQCTFI------KFFLHQQACFIFSLIWSIGGSCD-TDGRRVFDTFIRLIILGKDDEN 1810
+ + T+ K Q F+F+ W+ GG+ + D R F +
Sbjct: 2150 KRDENTWYPEKNPDKLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPSL-------- 2201
Query: 1811 PVPDSVGKWECPFDEKGLVYDYMYELKNKGRWVH-------------------------- 1844
PDS+ K FD+ LV++ G W H
Sbjct: 2202 -EPDSLAKVTYDFDK--LVHELFGNSSQVG-WKHWGQSQGRRRKGNCINLPTGECSIFGY 2257
Query: 1845 -----------WNELIKN------------TNL---GDKQIKIQDI-----IVPTMDTIR 1873
W++L+ N TNL G +KI + T DT
Sbjct: 2258 FVDIEQCEFIPWSDLVPNDQTLIQRGTSLLTNLQRSGGNFLKITECGECINYTATRDTTC 2317
Query: 1874 YTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKL 1906
+FLM L + + P+L G +G GK+ + L
Sbjct: 2318 LSFLMSLLLKNSCPVLLTGESGVGKTAAINQML 2350
Score = 409 bits (1050), Expect = e-113
Identities = 290/947 (30%), Positives = 449/947 (47%), Gaps = 177/947 (18%)
Query: 2309 VDNKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLC-------ANLLLARKE 2361
++N+ +L+K ++ D T +++ + +LF +DKL FSF LC AN L + +
Sbjct: 3582 LENEKNLLDKHIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDD 3641
Query: 2362 IEY---QELMFLLTGGV--SLKSAEKNPDPT------------WLQDKSWEEICR--ASE 2402
I + +E L G+ ++KSA T WL D W + C+ ++
Sbjct: 3642 IGFLPEEEWNIFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQ-CQYVSTH 3700
Query: 2403 FPAFRGLRQHFCEHIYEWREIYDSKEPH----------------NAKFPAPMD------- 2439
F L + ++ +W +SK + N K P +
Sbjct: 3701 LEPFSLLCKSLLSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNENKE 3760
Query: 2440 ---------KNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDS 2490
+ L Q++I+++ LRP+ + ++ ++T+K+G K+++ +L +Y S
Sbjct: 3761 TCNPINFPWEKLTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGS 3820
Query: 2491 NCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMI-KAAIEEGT 2549
N PLI + + G D LL+FA + + + ISLG+ Q A +I KA +
Sbjct: 3821 NARTPLILIQTHGIDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQ 3880
Query: 2550 WVCLQNCHLAVSWMPMLEKICEDFTSE--TCNSSFRLWLTSYPSSKFPVTILQNGVKMTN 2607
WV LQNCHLA S+MP L I E F S T + FRLWL+S S FP+ +L+ G+K+
Sbjct: 3881 WVFLQNCHLATSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAV 3940
Query: 2608 EPPTGLRLNLLQSYL---TDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGP 2664
E P GL+ NLLQ++ + V++ F G+ W+KLLF +CFF+A++ ERK +G
Sbjct: 3941 ESPQGLKSNLLQTFGCTGSGEVTEEIFENPDCGQW--WKKLLFSLCFFNAVINERKNYGI 3998
Query: 2665 LGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLT 2724
LGWNI Y FN SDL ++I+ L+ + +I ++A+ YL GE YGGRV D+WD+R L T
Sbjct: 3999 LGWNIAYKFNSSDLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKT 4058
Query: 2725 MLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDIS 2784
+L F N ++++ + FS S + +DYI I+ LP PE+ G+H S
Sbjct: 4059 LLYKFCNPEVLKD-DFSFSRS--------ASIKDYIHIIQSLPDDDLPEVLGIHPEAIRS 4109
Query: 2785 KDLQQTKTLFESLLLTQGGSKQTGAS------GSTDQILLEITKDILNKLPSDFDIEMAL 2838
Q + E+L+ Q K T A+ S D++++EI D+L +LP + E
Sbjct: 4110 CWETQGEKFIENLIAMQ--PKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIA 4167
Query: 2839 RKYPVRYEESMN-----------------------TVLVQEMERFNNLIITIRNTLRDLE 2875
P + M+ T L QE++RF+ L+ I +L+DL+
Sbjct: 4168 VGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQ 4227
Query: 2876 KAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDW--- 2932
AIKG +++ LE + S L +VP +W K +Y S KPL S+I D + RLNF W
Sbjct: 4228 LAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKV 4287
Query: 2933 ------------------------------------YNSGKPCVFWLSGFFFTQAFLTGA 2956
+ G P +WL FFF QAFL
Sbjct: 4288 AYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAV 4347
Query: 2957 MQNYARKYTTPIDLLGYEFEVIPSDT----------------------SDTSPEDGVYIH 2994
+Q+Y R +D L + VI + T S GVYI
Sbjct: 4348 LQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIF 4407
Query: 2995 GLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSD---------AYVCPL 3045
GL+++GARW+RE +L + P + P I+ PT+ S + A+ CP+
Sbjct: 4408 GLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPV 4467
Query: 3046 YKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 3092
Y+T ER L+TTG TNF+ ++ L T +P HWI VALLC+ ++
Sbjct: 4468 YQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCEKNE 4514
Score = 172 bits (435), Expect = 6e-42
Identities = 95/272 (34%), Positives = 149/272 (54%), Gaps = 11/272 (4%)
Query: 1894 TGTGKS--------VYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKG 1945
T TG S V KL+ + + IN S +A + + +I+ +L +R K
Sbjct: 2396 TATGSSDNPTKKPEVRTNKKLLKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKD 2455
Query: 1946 VFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIELI 2005
G P + +IFIDDMNMP + YGAQPP+EL+RQ D G YD + + + D+ ++
Sbjct: 2456 TLGAPKNNRILIFIDDMNMPVSDMYGAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIV 2515
Query: 2006 AAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGN 2065
AA P N ++PR ++HF++ + S + + IF + + Y + F PE +
Sbjct: 2516 AACVPVV---NDISPRLLKHFSMLVLPHPSQDILCTIFQAHLGIYFSINNFTPEVQKSKD 2572
Query: 2066 QIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVH 2125
QI++ ++ IY Q +N+LPTPTK HY FNLRD +++ G L +R V +K LFVH
Sbjct: 2573 QIISCSLAIYHQVRQNMLPTPTKCHYMFNLRDMFKLLLGLLQADRTVVNSKEMAALLFVH 2632
Query: 2126 EVLRVFYDRLINDDDRRWLFQLTKTVIKDHFK 2157
E RVF+DRLI+ D+ ++L +++ F+
Sbjct: 2633 EATRVFHDRLIDFTDKSLFYRLLSRELENCFQ 2664
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 605 bits (1560), Expect = e-172
Identities = 543/2068 (26%), Positives = 944/2068 (45%), Gaps = 233/2068 (11%)
Query: 321 QRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNL 380
+ LP I+LT+ +++F P F+++ ++R IP+ G +
Sbjct: 770 ENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIG-------IPNQFKGVGEAGD- 821
Query: 381 DTELPEHVLHWAVDTLKAA---VHRNLEGARKHYETYVEKYN-WLLDGTAVENIETFQTE 436
E + +D + + E + + ++ W++ G ++E E
Sbjct: 822 -----ESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQV--DMEAL-VE 873
Query: 437 DHTFDEYTEFIEKFLSL---ASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLN 493
H F + ++ + F +L E+ LP + + ++C +KT + + + ++L+
Sbjct: 874 KHLFTVH-DWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVL 932
Query: 494 DIASKYRKENECICSEFEAIKEHALKV----PETTEEMMDLISYVEKARTVGIEELILRI 549
+ +K + E + A++V P++ EE+ D K +
Sbjct: 933 SL----KKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSK------------L 976
Query: 550 QESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKEN-ELMAK 608
QE K ++ L +F ++ L TV E I N K K + ELM +
Sbjct: 977 QERKPEI---LPLFQEAEDKNRLLRTVA----------GGGLETISNLKAKWDKFELMME 1023
Query: 609 REKLIL----EIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEE 664
+L++ E+ K + + + ELE+ + ++ I+ + ++K +
Sbjct: 1024 SHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNT--LDKSAK 1081
Query: 665 LFKWELTKYPELDKLKVNIEPYQKFF-----NFVLKWQRSEKRWMDGGFLDLNGESMEAD 719
L K + ++ +L+ + + F NF L S K + E +
Sbjct: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSIS-KDIESCAQIWAFYEEFQQG 1140
Query: 720 VEEFSRE---IFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEE-PKDNATITMCR-- 773
+E + E F+T + + ++ + + S+ K++ E K I + +
Sbjct: 1141 FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV 1200
Query: 774 ----MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLE-------QFEVISAGASK 822
+ HW + ++G GT+L K+L +L + + +++ A
Sbjct: 1201 RGEHLSPDHWLDLFRLLGLP----RGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQG 1256
Query: 823 EFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD---DQIIKTQTMRGSP 879
E ++ +A+ + F + Y D+ + + + + I++ D Q+++ SP
Sbjct: 1257 EVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSP 1316
Query: 880 FIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVD 939
+ K FE ++ WE +L + E + +Q +W+YLEPIF +P+E +F VD
Sbjct: 1317 YYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRG----ALPKEQTRFNRVD 1372
Query: 940 RHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFL 999
+R IM KD +V T+ G+ L + L++ K LN +LE+KR FPRF+F+
Sbjct: 1373 EDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFI 1432
Query: 1000 SNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEF-LPNLDIKAMYSSEGERVELIALIST 1058
+D++LEIL ++ +P +Q HLKK F GI + F + I AM S EGE V +
Sbjct: 1433 GDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPL 1492
Query: 1059 SAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTS 1118
S VE WL + M +++ ++ S +P Q++ Q+ +T
Sbjct: 1493 S---NNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTE 1549
Query: 1119 ETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTT------LGALVTIDVHAR 1172
+ + I L + +L N+L + + + L AL+ +H
Sbjct: 1550 DVENAIKD--HSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNI 1607
Query: 1173 DVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR-VRIINCNVKYAYEYLGNSPRLVITPL 1231
DVV + ++ V D+ W QLR+Y ++++ V++++ +Y YEY GN+ +LV TPL
Sbjct: 1608 DVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPL 1667
Query: 1232 TDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKF 1291
TD+CY TL A + LGG P GPAGTGKTE+ K L L Q +VFNC +G+D +MG+
Sbjct: 1668 TDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRI 1727
Query: 1292 FKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFV 1351
F GL GAW CFDEFNR+E VLS V+ QI IQ A++ V G E+++N N +
Sbjct: 1728 FVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGI 1787
Query: 1352 AITMNP---GYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVM 1408
ITMNP GY GR +LPDNLK LFR VAM P+ LIAE+ LYS GF +A+ LS K+V
Sbjct: 1788 FITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVA 1847
Query: 1409 TYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKY------PNENEDILLLRSIKDVNE 1462
+ L E L+ Q HYD+G+RA+K VL +GNL + N NE +++++++
Sbjct: 1848 IFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTM 1907
Query: 1463 PKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYE 1522
KF D F+ + D+FPGI+L E +Y E + N + + ++K ++ YE
Sbjct: 1908 SKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYE 1967
Query: 1523 MMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYR-TVNPKSITMGQLF 1581
+ R G ++VG A K+ + +L L + KV+ + T+NPK++ QL
Sbjct: 1968 QLCQRMGVVIVGPSGAGKSTLWRMLRAALC--------KTGKVVKQYTMNPKAMPRYQLL 2019
Query: 1582 GQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLM 1641
G D + EW+DG++ N+ R+ W++ DG ID WIES+N+VLDDN+ L +
Sbjct: 2020 GHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMP 2079
Query: 1642 SGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCE 1701
SGE IQ P ++ +FET DLS ASPAT+SR GMI+L + L+ SWL +
Sbjct: 2080 SGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPA---- 2135
Query: 1702 PEYQALLRGLFAWLIPPSLNQRVELFQLNYLY-TTIVSKILKILITFRISNYFKYVPLKT 1760
EY+ L +L + L Q +Y+ T++V ++ L
Sbjct: 2136 -EYRNNLENWIGDYFEKAL--QWVLKQNDYVVETSLVGTVMNGL---------------- 2176
Query: 1761 QCTFIKFFLHQQAC-----FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDS 1815
H C FI +LI +GG+ + R F K+ + +S
Sbjct: 2177 --------SHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFT---------KEVFHWARES 2219
Query: 1816 VGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLG----DKQIKIQDIIVPTMDT 1871
+ P D Y +GR + L K +L + + I P M
Sbjct: 2220 PPDFHKPMD--------TYYDSTRGRLATY-VLKKPEDLTADDFSNGLTLPVIQTPDMQR 2270
Query: 1872 IRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQV 1931
F LS +P + VGP G GK + ++ + L Q ++ SA+T++ +
Sbjct: 2271 GLDYFKPWLSSDTKQPFILVGPEGCGKGMLLR-YAFSQLRSTQIAT--VHCSAQTTSRHL 2327
Query: 1932 -----QNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCG 1986
Q ++ + R V+ P ++ ++++ D+N+P L+K+G + L+Q
Sbjct: 2328 LQKLSQTCMVISTNTGR--VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQ 2385
Query: 1987 HWYDLKDTSKITLVDIELIAAMGPPGG-GRNPVTPRCIRHFNICSINSFSDETMVRIFSS 2045
+YD ++ + L +I+++A+M G GR+ +T R +CSI+ E + I+ +
Sbjct: 2386 GFYD-ENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGA 2444
Query: 2046 IVAFYLRTHEFPPEYFVIGNQ----IVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRV 2101
+ L H+ + + G+ ++ G+M + V SHY F ++
Sbjct: 2445 YLEPVL--HKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQW 2502
Query: 2102 IRGCLLIERDAVANKHTM---IRLFVHEVLRVFYDRLINDDDRRWLFQLTKTV------- 2151
+ G + + ++ H + + + +E R+F D+++ + LF + T
Sbjct: 2503 VLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELH-LFDIILTSVFQGDWG 2561
Query: 2152 --IKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFS 2209
I D+ +SF+ + A G + P + ++ N
Sbjct: 2562 SDILDNMSDSFYVTWGARHNSGARAAP--------GQPLPPHGKPLGKL-----NSTDLK 2608
Query: 2210 DVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRL 2269
DV+ + L Y + ++ +++++F VLE++SRI RVL GG+ LL G G GR+++T L
Sbjct: 2609 DVIKKGLIHYGRDNQ-NLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSL 2667
Query: 2270 ATSMAKMHIFQPEISKSYGMNEWREDMK 2297
+ M +F P+IS+ Y + +++ D+K
Sbjct: 2668 VSHMHGAVLFSPKISRGYELKQFKNDLK 2695
Score = 254 bits (650), Expect = 7e-67
Identities = 227/847 (26%), Positives = 384/847 (45%), Gaps = 56/847 (6%)
Query: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNK--SKILEKRL 2320
R + LA S +KM+ ++SK M +R + +F+ + R + NK S+ E+R+
Sbjct: 3496 RDAYLPLAESASKMYFIISDLSKINNM--YRFSLAAFLRL--FQRALQNKQDSENTEQRI 3551
Query: 2321 RYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLAR-KEIEYQELMFLLTGGVSLK- 2378
+ L + +Y ICR LF+ D+L+F+ + +E E+ ++ G + K
Sbjct: 3552 QSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKA 3611
Query: 2379 -SAEKNPD--PTWL-QDKSWEEICRASEFPAFRGLRQHFC-EHIYEWREIYDSKEPHNAK 2433
S +K D P+W+ Q++SW P+ L Q C E WR Y++ +
Sbjct: 3612 DSQQKIRDQLPSWIDQERSWAVATLKIALPS---LYQTLCFEDAALWRTYYNNSMCEQ-E 3667
Query: 2434 FPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCT 2493
FP+ + K ++ Q+I++++ LRPD++ A+ + LG K V P P +L + Y ++
Sbjct: 3668 FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEI 3727
Query: 2494 IPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553
P++ ++SPGADP L + AN SG + +++GQGQ +A +M+K G W+CL
Sbjct: 3728 EPILIIISPGADPSQELQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL 3786
Query: 2554 QNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTGL 2613
+N HL VSW+P+LEK + + +FRLWLT+ F +LQ+ +K+T E P GL
Sbjct: 3787 KNLHLVVSWLPVLEK---ELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGL 3843
Query: 2614 RLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGF 2673
+ NL+++Y + PE A LF + +FHA QER+ + P GW Y F
Sbjct: 3844 KKNLMRTYES---WTPEQISKKDNTHRA--HALFSLAWFHAACQERRNYIPQGWTKFYEF 3898
Query: 2674 NESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLY 2733
+ SDLR + + + +E + L YGGR+ + +D R+L + L F+N
Sbjct: 3899 SLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSS 3958
Query: 2734 IVENPHYKFSPS---GNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQT 2790
+++ + + S + P + DY I+K+P P FGL N+ S +
Sbjct: 3959 VIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMIS 4018
Query: 2791 KTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPS-DFDIEMALRKYPVRYEESM 2849
+ L + G T S +I +LN + + + +K P +
Sbjct: 4019 SQVISQLRIL--GRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG 4076
Query: 2850 NTVL-VQEMERFN--NLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAK 2906
+ +L +E+FN L+ ++ +L L K I+G ++ S ++ L+ +LL K P W
Sbjct: 4077 SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQS 4136
Query: 2907 RSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFW-----LSGFFFTQAFLTGAMQNYA 2961
+ PL Y+ +AR +Q+W + + LS F FL Q A
Sbjct: 4137 KWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETA 4195
Query: 2962 RKYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDL 3021
R +D L + V + + I GL L+G +D + + +
Sbjct: 4196 RAVGRSVDSLKF---VASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSV 4252
Query: 3022 MPII--WIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHW 3079
+P WI + P+Y ++ER + TN + DQ W
Sbjct: 4253 LPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVV------TNIDVPCGGNQDQ----W 4302
Query: 3080 IKRGVAL 3086
I+ G AL
Sbjct: 4303 IQCGAAL 4309
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 435 bits (1118), Expect = e-121
Identities = 272/824 (33%), Positives = 423/824 (51%), Gaps = 43/824 (5%)
Query: 2282 EISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLFE 2341
++SK + M ++ S + R ++S L +R+ L D T+++Y R LFE
Sbjct: 3 DLSKIHPMYQFSLKAFSIVFQKAVERAAPDES--LRERVANLIDSITFSVYQYTIRGLFE 60
Query: 2342 KDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRAS 2401
DKL + L +LL +E+ EL FLL V +A +L ++W + S
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASP---VEFLSHQAWGAVKVLS 117
Query: 2402 EFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITP 2461
F L + W++ +S+ P K P KN LQ++ +LR +RPD++T
Sbjct: 118 SMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTY 176
Query: 2462 AITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSG 2521
A+ ++V +KLG K+V D S+ +S P+ F+LSPG DP+ + +
Sbjct: 177 ALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTF 236
Query: 2522 NK--FQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCN 2579
N F +SLGQGQ +A + A ++G WV LQN HL W+ LEK E+ SE +
Sbjct: 237 NNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEH-SENSH 295
Query: 2580 SSFRLWLTSYPSSK-----FPVTILQNGVKMTNEPPTGLRLNL---LQSYLTDPVSDPEF 2631
FR+++++ P+ P IL+N +K+TNEPPTG+ NL L ++ D +
Sbjct: 296 PEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLE---- 351
Query: 2632 FKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINE 2691
+E ++ +LF +C+FHA+V ER+KFGP GWN Y FN DL IS+ L F+
Sbjct: 352 ---MCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEA 408
Query: 2692 YDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAP 2751
+P++ + YL GE YGG +TDDWDRRL T L +F ++E + S + + P
Sbjct: 409 NAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLP 465
Query: 2752 PKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQT--GA 2809
Y Y ++I + P ++GLH N +I Q ++ LF ++L Q Q GA
Sbjct: 466 GNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGA 525
Query: 2810 SGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRN 2869
+ ++ + + ++IL ++ +F+I + K V V QE R N L I+
Sbjct: 526 GATREEKVKALLEEILERVTDEFNIPELMAK--VEERTPYIVVAFQECGRMNILTREIQR 583
Query: 2870 TLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFL 2929
+LR+LE +KG + M S +E L +L VPE WA+R+YPS L ++ D L R+ L
Sbjct: 584 SLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKEL 643
Query: 2930 QDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSD--TS 2986
+ W P WL+GFF Q+FLT MQ+ ARK P+D + + ++ + + +
Sbjct: 644 EAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSP 703
Query: 2987 PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLY 3046
P +G YIHGL+++GA WD ++G++ E K L MP+++IK + Y CP+Y
Sbjct: 704 PREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVY 763
Query: 3047 KTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3090
KTS+R T +V LKT + W+ GVALL Q+
Sbjct: 764 KTSQRGPT---------YVWTFNLKTKENPSKWVLAGVALLLQI 798
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 162 bits (410), Expect = 5e-39
Identities = 214/978 (21%), Positives = 378/978 (38%), Gaps = 144/978 (14%)
Query: 848 RDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLK 907
+D+G ILS +Q + + + + W + + ++ WL
Sbjct: 1201 KDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLT 1260
Query: 908 VQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTG---- 963
Q +W++L + I + +F+ +D +R +M+ DP VL+ +
Sbjct: 1261 FQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSP 1320
Query: 964 ------LLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRV 1017
L + LQ + LE I+ L + L FPR FFLS+ E++ +L+ +
Sbjct: 1321 YFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEA 1380
Query: 1018 QPHLKKCFEGIAKLEFLP------NLDIKAMYSSEGERVELIALISTSAARGAVE----- 1066
Q +++CF + + F N D + +VE +A++ ++
Sbjct: 1381 QLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPL 1440
Query: 1067 -----KWLIQVED-LMLRSVHDV--IAAARLAYPESARR--------------------- 1097
KWL +E L L VH + AARLA S
Sbjct: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500
Query: 1098 DWVREWPGQVVLCISQMFWTSETQE-VISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQ 1156
D V+ +P Q VL ++ W +E +E ++ GT + + +L +V +R + + Q
Sbjct: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH---MRKLEVLVNFMRAQRASQ 1557
Query: 1157 ---------TRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENEN---- 1203
+ L AL+ + V RD+ + + VS TDF W+ QL+Y+ + +
Sbjct: 1558 GGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPK 1617
Query: 1204 --------------------ARVRIINCNVKYAYEYLGNSPRLVITP--LTDRCYRTLIG 1241
+ ++ + Y YEYLG PRL P L +R L+
Sbjct: 1618 SPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLL 1675
Query: 1242 AFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAW 1301
A G GP G GK LA+AL Q V+ CS ++ + + G GAW
Sbjct: 1676 ALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 1735
Query: 1302 ACFDEFNRIELEVLSVVAQQI-----LCIQRAIQQKLVVFVFEGTELKLNPNCFVA---I 1353
++ +++ +LS + Q++ L + + T+ +L + F +
Sbjct: 1736 LLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHV 1795
Query: 1354 TMNPGY-------AGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKI 1406
++ GY A S +P NL +L R VA+ +P+ +AE++L G +A ++ ++
Sbjct: 1796 SVRLGYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRL 1855
Query: 1407 VMTYRLCSEQLSSQFHYDYGMR------AVKAVLVAAGNLKLKYPNEN---EDILLLRSI 1457
+ L E +S + ++ + V K + P E+ LLRS
Sbjct: 1856 SKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRS- 1914
Query: 1458 KDVNEPKF-LSHDIPLFN--GITSDLFPGIKLPEAD---YHEFLECAHEACNVHNLQPVK 1511
P F + + + L N G+ LFP A+ Y E L P
Sbjct: 1915 -----PLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSP 1969
Query: 1512 FFLEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVL---ADTLTLMNEHGYGEEEKVIYR 1568
L + Q + + G +L+G + KT H L + L M + + V
Sbjct: 1970 DILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEIT 2029
Query: 1569 TVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRK-----------WVVFD 1617
+ P ++ + G + W GI R +K W++ D
Sbjct: 2030 HLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087
Query: 1618 GPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYL 1677
G + W++S+ +L + +L L SG+ I P L+ E D + SP V C +++
Sbjct: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWC 2147
Query: 1678 EPSQLGWEPLVSSWLNSL 1695
Q W+ ++S+ + SL
Sbjct: 2148 GGEQT-WQCILSALMASL 2164
Score = 88.6 bits (218), Expect = 9e-17
Identities = 191/868 (22%), Positives = 306/868 (35%), Gaps = 114/868 (13%)
Query: 2311 NKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFL 2370
N + L L L H T L + +L L L LL A + E + L
Sbjct: 3898 NHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELERLAL 3957
Query: 2371 LTG------GVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIY 2424
G V K P WL K+W E P F GL H W+
Sbjct: 3958 WPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYL 4017
Query: 2425 DSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLT 2484
P P + L+ LQK+I+ R LRP+ + A+ ++ T LG+ ++ + T
Sbjct: 4018 SLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRP-LDENTYAPT 4076
Query: 2485 KSYLDSNCTIPLIFVLSPGADPMASL------LKFANDKSMSGNKFQAISLG-QGQGPIA 2537
+ S T P++ +L P P A+L K A + Q I+LG + P++
Sbjct: 4077 MPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVS 4136
Query: 2538 --AKMIKAAIEEGTWVCLQNCHLAVSWMPML----------EKICEDFTSE--------- 2576
+ A+ EG W+ L NCHL W L K+ D SE
Sbjct: 4137 VVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESR 4196
Query: 2577 ---TCNSSFRLWL--TSYPSSKFPVTILQNGVKMTNEPPTGLRLNL-LQSYLTDPVSDPE 2630
T + FRLWL + S+ P + Q+ + P +L L L D V +
Sbjct: 4197 NVSTVHRDFRLWLIVPAESSASLPAVLTQHSM------PVFWNQSLELGHVLIDSVELAQ 4250
Query: 2631 FFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDL-RISIRQLQLFI 2689
+ A LL H L+ R+ +G +++ L ++ Q QL+
Sbjct: 4251 QVLYMQPPTQALPLLL-----LHGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQTQDQLWA 4305
Query: 2690 NEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTM----LADFYNLYIVENPHYKFSPS 2745
+ + P A+ L YGG + D DR L+++ L+ ++ PH S
Sbjct: 4306 SLSN--PRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWV--QPHTPQSLL 4361
Query: 2746 GNYFAPPKGTYEDYIEFIKK----LPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQ 2801
P+ D + K LP P + GL E +Q++ L +L +
Sbjct: 4362 ATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSS 4421
Query: 2802 G---GSKQTGASGSTDQI---------LLEITKDILNKLPSDFDIEMALRKYPVRYEESM 2849
+ GA + ++ LE +D+L + + + +
Sbjct: 4422 PVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPL 4481
Query: 2850 NTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDS-ALEALSGSLLVGKVPEIWAKRS 2908
VL E + L+ T++ L L + +KG S A++ +L G++P W +
Sbjct: 4482 EGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHA 4541
Query: 2909 YPSLKPLGSYITDFLARLNFLQDWYNSGKPC-------VFWLSGFFFTQAFLTGAMQNYA 2961
+P ++ R L + G VF LS F + L A
Sbjct: 4542 PAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAA 4601
Query: 2962 RKYTTP-IDLLGYEFEV-------------------IPSDTSDTSPEDGVYIHGLYLDGA 3001
P + G V + + + T PE G+ + GL + A
Sbjct: 4602 LDQNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHA 4661
Query: 3002 RWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDA----YVCPLYKTSERKGTLST 3057
WD +G L + L P+ + + + A Y CP+Y G L T
Sbjct: 4662 EWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY----MGGPLGT 4717
Query: 3058 TG-HSTNFVIAMLLKTDQPTRHWIKRGV 3084
S N V+ + L T ++R V
Sbjct: 4718 AKLQSRNIVMHLPLPTKLTPNTCVQRRV 4745
Score = 77.4 bits (189), Expect = 2e-13
Identities = 89/415 (21%), Positives = 160/415 (38%), Gaps = 54/415 (13%)
Query: 1775 FIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMY 1834
F+F+LIW G + +FDTFIR I + P S LV+D ++
Sbjct: 2287 FLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSA-----------LVFD-LH 2334
Query: 1835 ELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPT 1894
G V + ++++ P++ T R +++DL ++ +P+L G
Sbjct: 2335 VSPEDGTLVPFTGQYLSSHIKGTLGTFH----PSIQTERLLYVVDLLLSGGQPVLLAGEA 2390
Query: 1895 GTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKK 1954
TGKS +V+ + H Y P + S+ + I + +
Sbjct: 2391 ATGKSAFVEVLVEPH-HPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPS 2449
Query: 1955 CIIFIDDMNMPALE-KYGAQPPIELLRQFFDCGHWYDLKDTSKITLVD-IELIAAMGPPG 2012
+ ++D+++ + + QP +E LRQ D G Y TL + +A + PG
Sbjct: 2450 LLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVPG 2508
Query: 2013 GGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTM 2072
P+ PR R F + ++ S + T++ I+ +L + +V ++
Sbjct: 2509 YCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASV 2568
Query: 2073 EIYKQSVENLLPTPTKSHYTFNLRDFSRV------------------------------- 2101
E ++ +P+P HY F+L S +
Sbjct: 2569 EAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSG 2628
Query: 2102 IRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHF 2156
+RG L A N ++RL++HE R F DRL + +R + +L V + F
Sbjct: 2629 LRGTCLTVMMATRN---VVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 55.1 bits (131), Expect = 1e-06
Identities = 94/442 (21%), Positives = 180/442 (40%), Gaps = 57/442 (12%)
Query: 332 FDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVN---LDTELPEHV 388
+++ + DLE + L +++AE + + + L V E
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 389 LHWAVDTLKAAVHRNLEGARKHYET----YVEKYNWLLDGTAVENIETFQTEDHTFDEYT 444
+ V +L LE K E VEK N +L Q + E
Sbjct: 877 MEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMIL-----------QMREGQKKEIE 925
Query: 445 EFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANIL---LNDIASKYRK 501
+K + I +L + Y + E + KAK L L D +K +K
Sbjct: 926 ILTQKLSAKEDSIHILNE--EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKK 983
Query: 502 ENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQES-KRQMSYFL 560
E ++ AL++ + ++ + + +A + GI + + R++ + K Q+
Sbjct: 984 E----------LENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLT 1033
Query: 561 DVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKES 620
+V LN + +W +K+N +E E+ E +KE E+ ++K++L ++
Sbjct: 1034 EV-----HRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1088
Query: 621 RRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLK 680
+E T E E ++Q T + +LQ+++++ V + ++E K L+KL+
Sbjct: 1089 EMNKEITWLKE-EGVKQDTT-LNELQEQLKQKSAHVNSLAQDETKLK------AHLEKLE 1140
Query: 681 VNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKK 740
V++ K N L+ Q E L + E + V E + ++ T + FQ+ LK
Sbjct: 1141 VDLNKSLK-ENTFLQEQLVE--------LKMLAEEDKRKVSELTSKLKTTDEEFQS-LKS 1190
Query: 741 ELQEKRKAARKRSLEEEKIEEE 762
++ K+ +SLE +K+ EE
Sbjct: 1191 SHEKSNKSLEDKSLEFKKLSEE 1212
Score = 38.9 bits (89), Expect = 0.080
Identities = 82/413 (19%), Positives = 168/413 (40%), Gaps = 67/413 (16%)
Query: 305 RRTVEGFVKLFDPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNV 364
++ ++G + K +R+ + EL D + L++ + +E + + +
Sbjct: 171 KKKLQGILSQSQDKSLRRIAELREELQMDQQAKKH------LQEEFDASLEEKDQYISVL 224
Query: 365 QTIPSWLSGT--STPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLL 422
QT S L + P+N+D P L +A V E E VE
Sbjct: 225 QTQVSLLKQRLRNGPMNVDVLKPLPQLE-----PQAEVFTKEENPESDGEPVVE------ 273
Query: 423 DGTAVENIETFQT----EDHTFDEYTEFI----EKFLSLASEIMLLPQWIHYTMVRLD-C 473
DGT+V+ +ET Q +++ E I E+ L SE L + + + L+
Sbjct: 274 DGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKI 333
Query: 474 EDL----KTGLTNKAKAFANILLN-------DIASKYRKENECICSEFEAIKEHALKVPE 522
+DL KT L + + N++ IA R+ +E + + E I + ++ +
Sbjct: 334 KDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 393
Query: 523 TTEEMMDLISYVEKARTVGIEEL------ILRIQESKRQMSYFLDVFL------FPQEDL 570
T + +L EK+ EEL + +E++R++ +D + +E +
Sbjct: 394 MTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERI 453
Query: 571 ALNATVLMWPRKINPIFDE-NDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEF 629
+L + +++ + + ++E I + E EL K ++L +++ R +E +
Sbjct: 454 SLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKV 513
Query: 630 A-------------ELERMQQYVTDVRQLQKR--IQESEEAVQFINKEEELFK 667
A E E+ + + +LQK+ + ESE ++ + +E E ++
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYR 566
Score = 38.9 bits (89), Expect = 0.080
Identities = 133/734 (18%), Positives = 285/734 (38%), Gaps = 92/734 (12%)
Query: 268 INLFTKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFDPKDQQRLPIFK 327
+ + +KE E + E+L+ + T N+L+DL + + R I +
Sbjct: 523 LKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA-----------ETYRTRILE 571
Query: 328 IELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELPEH 387
+E + + E +DL V AE ++ + I + T + +
Sbjct: 572 LESSLEKSLQENKNQSKDL------AVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 388 VLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFI 447
+ + LK +E R+ E EK L D + + + T ++
Sbjct: 626 LWTEKLQVLKQQYQTEMEKLREKCEQ--EKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQ 683
Query: 448 EKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECIC 507
+ SL+SE+ + + H L + T+K K +++ + ++++ + I
Sbjct: 684 TELESLSSELSEVLKARHKLEEEL---SVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI- 739
Query: 508 SEFEAIKEHALKVPETTEEMMDLISYVE-------------KARTVGIEELILRIQESKR 554
IKEH + + T + + D I+ +E +A +E I R + +
Sbjct: 740 -----IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 794
Query: 555 QMSYFLDVFLFPQ-----EDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKR 609
Q S LDVF Q + A + +K+ + E L K+ E+ A++
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-----KQVAEVEAQK 849
Query: 610 EKLILEIEKESRRMEEFTEFAELE--RMQQYVTDVRQ-----LQKRIQESEEAVQ-FINK 661
+ + E++ ++++ + E + M+Q V + Q L+ +E E+ Q + K
Sbjct: 850 KDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEK 909
Query: 662 EEELFKWELTKYPELDKLKVNIEPYQKFFN-----FVLKWQRSEKRWMDGGFLDLNGESM 716
E + + + E++ L + + + + K++ EK+ E +
Sbjct: 910 ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM----------EKV 959
Query: 717 EADVEEFSREIFKTLKFFQTKLKKELQ-------EKRKAARKRSLEEEKIEEEPKDNATI 769
+ +E + K L + KLKKEL+ +K K + LE + +A
Sbjct: 960 KQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVS 1019
Query: 770 TMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKA 829
+ + + ++E+ +L D + K L E E+ +E + K
Sbjct: 1020 RLETNQKEQIESLTEVHRRELN-DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
Query: 830 MNTMIG-TWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEI 888
+ G E++ I+ ++ GV ++++E+Q L + ++ E ++
Sbjct: 1079 KILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD------ETKL 1132
Query: 889 KAWEDRL-IRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMK 947
KA ++L + + +++ E +Q Q + L+ + +E+ +++ E + +T D ++ +
Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKML--AEEDKRKVSELTSKLKTTDEEFQSLKS 1190
Query: 948 FCAKDPKVLAATSL 961
K K L SL
Sbjct: 1191 SHEKSNKSLEDKSL 1204
Score = 33.5 bits (75), Expect = 3.3
Identities = 62/329 (18%), Positives = 125/329 (37%), Gaps = 45/329 (13%)
Query: 483 KAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETT--EEMMDLISYVEKARTV 540
K KA + + I +E + E +K+ + V + + E++ L EK
Sbjct: 432 KLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 491
Query: 541 GIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK 600
+EL ++Q +R+ + V L + L KI+ ++ + L
Sbjct: 492 KEQELTKKLQTREREFQEQMKVALEKSQSEYL---------KISQEKEQQESLALEELEL 542
Query: 601 KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFIN 660
++ ++ + E + ++++E+ T ELE + + LQ+ +S++ +
Sbjct: 543 QKKAILTESENKLRDLQQEAETYR--TRILELESSLE-----KSLQENKNQSKDLAVHLE 595
Query: 661 KEEELFKWELTKYPE-----------------LDKLKVNIEPYQKFFNFVLKWQRSEKRW 703
E+ E+T E +KL+V + YQ + + EK
Sbjct: 596 AEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKET 655
Query: 704 MDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLK---KELQEKRKAARKRSLEEEKIE 760
+ L +A +EE + + + L QT+L+ EL E KA K E ++
Sbjct: 656 L----LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 711
Query: 761 EEP---KDNATITMCRMRARHWKQISEIV 786
++ K M + H +Q+ I+
Sbjct: 712 DQTDKMKQELEAKMDEQKNHHQQQVDSII 740
Score = 32.0 bits (71), Expect = 9.7
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 23/257 (8%)
Query: 584 NPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFA-----ELERMQQY 638
N FD +E+ K K E K L E++ ++ R+ E + E+E + +
Sbjct: 1492 NKRFDCLKGEMEDDKSKMEK----KESNLETELKSQTARIMELEDHITQKTIEIESLNEV 1547
Query: 639 VTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQR 698
+ + Q QK I E +E VQ + +EL + + + E ++ + +E L+ ++
Sbjct: 1548 LKNYNQ-QKDI-EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKK 1605
Query: 699 SEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEK 758
E ++L+ +S E +++ + +LK++ ++K A +K+ L + +
Sbjct: 1606 KELE-----HVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQME 1660
Query: 759 IEEEPKDNAT-------ITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLE 811
+EE T T + R R + E + + S T + N+ Y E
Sbjct: 1661 EKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTE 1720
Query: 812 QFEVISAGASKEFSLEK 828
Q E S G ++ EK
Sbjct: 1721 QEEADSQGCVQKTYEEK 1737
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.0 bits (123), Expect = 9e-06
Identities = 80/372 (21%), Positives = 160/372 (43%), Gaps = 63/372 (16%)
Query: 413 TYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLD 472
TY+EK D ++E T++ ++ E EK + SE + ++L+
Sbjct: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE---------KSEIQLN 240
Query: 473 CEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLIS 532
+DLK L L A + KE + + ++ +A E E+ +L++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE--------NELWNLLN 292
Query: 533 YVEKARTVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDE 592
++ + EE +IQE + +M QE MW ++ E +E
Sbjct: 293 QQQEEKMWRQEE---KIQEQEEKMC--------EQELKIREQEEKMWRQEEK--MHEQEE 339
Query: 593 LIENAKHK--KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQ 650
I + K ++ E + ++E+ I E E++ R EE + E++Q+ ++ + +++I+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD-EKIQEQEEEMWRQEEKIR 398
Query: 651 ESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLD 710
E EE ++E++++ E + +K++ E W++ EK +
Sbjct: 399 EQEE-----KRQEKMWRQEKKMREQDEKIREQEEEM---------WRQEEK------IRE 438
Query: 711 LNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKI-EEEPKDNATI 769
L E M D EE RE+ + K+++E ++ ++ K +EEKI E+E K
Sbjct: 439 L--EEMMQDQEEKLREV-------EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 770 TMCRMRARHWKQ 781
+ + + W+Q
Sbjct: 490 KLLKQEEKIWEQ 501
Score = 47.4 bits (111), Expect = 2e-04
Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 60/251 (23%)
Query: 498 KYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMS 557
K R++ E + + E I+E K+ E EEM +E +R QE KRQ
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWR-------------QEEKIREQEEKRQEK 407
Query: 558 YFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK--KENELMAKREKLILE 615
MW ++ E DE I + + ++ E + + E+++ +
Sbjct: 408 --------------------MWRQEKK--MREQDEKIREQEEEMWRQEEKIRELEEMMQD 445
Query: 616 IEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPE 675
E++ R +EE + E E+MQ+ +++ +++IQE EE ++E+L K E + +
Sbjct: 446 QEEKLREVEEKMQEEE-EKMQEQEEKIQRQEEKIQEQEEKTW---RQEKLLKQEEKIWEQ 501
Query: 676 LDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQ 735
+K+ W++ EK W + E M+ EE RE + ++ +Q
Sbjct: 502 EEKM----------------WRQEEKMWEQEEKMQEQEEKMQRQ-EEKMRE--QEVRLWQ 542
Query: 736 TKLKKELQEKR 746
+ K + QE R
Sbjct: 543 QEEKMQEQEVR 553
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 52.0 bits (123), Expect = 9e-06
Identities = 80/372 (21%), Positives = 160/372 (43%), Gaps = 63/372 (16%)
Query: 413 TYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLD 472
TY+EK D ++E T++ ++ E EK + SE + ++L+
Sbjct: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE---------KSEIQLN 240
Query: 473 CEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLIS 532
+DLK L L A + KE + + ++ +A E E+ +L++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE--------NELWNLLN 292
Query: 533 YVEKARTVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDE 592
++ + EE +IQE + +M QE MW ++ E +E
Sbjct: 293 QQQEEKMWRQEE---KIQEQEEKMC--------EQELKIREQEEKMWRQEEK--MHEQEE 339
Query: 593 LIENAKHK--KENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQ 650
I + K ++ E + ++E+ I E E++ R EE + E++Q+ ++ + +++I+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD-EKIQEQEEEMWRQEEKIR 398
Query: 651 ESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLD 710
E EE ++E++++ E + +K++ E W++ EK +
Sbjct: 399 EQEE-----KRQEKMWRQEKKMREQDEKIREQEEEM---------WRQEEK------IRE 438
Query: 711 LNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKI-EEEPKDNATI 769
L E M D EE RE+ + K+++E ++ ++ K +EEKI E+E K
Sbjct: 439 L--EEMMQDQEEKLREV-------EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 770 TMCRMRARHWKQ 781
+ + + W+Q
Sbjct: 490 KLLKQEEKIWEQ 501
Score = 47.4 bits (111), Expect = 2e-04
Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 60/251 (23%)
Query: 498 KYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMS 557
K R++ E + + E I+E K+ E EEM +E +R QE KRQ
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWR-------------QEEKIREQEEKRQEK 407
Query: 558 YFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHK--KENELMAKREKLILE 615
MW ++ E DE I + + ++ E + + E+++ +
Sbjct: 408 --------------------MWRQEKK--MREQDEKIREQEEEMWRQEEKIRELEEMMQD 445
Query: 616 IEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPE 675
E++ R +EE + E E+MQ+ +++ +++IQE EE ++E+L K E + +
Sbjct: 446 QEEKLREVEEKMQEEE-EKMQEQEEKIQRQEEKIQEQEEKTW---RQEKLLKQEEKIWEQ 501
Query: 676 LDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQ 735
+K+ W++ EK W + E M+ EE RE + ++ +Q
Sbjct: 502 EEKM----------------WRQEEKMWEQEEKMQEQEEKMQRQ-EEKMRE--QEVRLWQ 542
Query: 736 TKLKKELQEKR 746
+ K + QE R
Sbjct: 543 QEEKMQEQEVR 553
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.9 bits (115), Expect = 8e-05
Identities = 58/276 (21%), Positives = 128/276 (46%), Gaps = 19/276 (6%)
Query: 492 LNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYV-EKARTVGIEELILRIQ 550
L + K RK+ E + + E ++E K+ E E+M + E+ + + +E LR Q
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 551 ESKRQMSYFL---DVFLFPQEDLALNATVLMWPRKINPIFDENDELIENA-KHKKENELM 606
+ R+ + + ++ QE+ MW R+ ++++ ++ E K + + E M
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMW-RQEERLWEQEKQMREQEQKMRDQEERM 399
Query: 607 AKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELF 666
++++ + E E+ R E+ E ++E+M++ +++ +K+ ++ EE +Q +EE +
Sbjct: 400 WEQDERLREKEERMREQEKMWE--QVEKMRE-EKKMQEQEKKTRDQEEKMQ---EEERIR 453
Query: 667 KWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSRE 726
+ E E + ++ E QK + W++ EK W + + E + + E
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENM--WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 727 IFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEE 762
K ++ + K QE+ K+ +EK+ E+
Sbjct: 512 -----KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Score = 45.8 bits (107), Expect = 7e-04
Identities = 58/300 (19%), Positives = 132/300 (44%), Gaps = 55/300 (18%)
Query: 498 KYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMS 557
K R+E E + + E ++E K+ E E+M + +E ++ QE K
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWE-------------QEEKMQEQEEK---- 639
Query: 558 YFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILE-- 615
++ QE+ MW ++ P ++ ++L E+ K +++ ++ + EK+ +
Sbjct: 640 ------MWEQEEKMWEQEEKMWEQQRLP--EQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 616 IEKESRRMEEFT----EFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELT 671
+EK+++ E+ T + E E M++ +R+ ++ ++E EE +Q +EE++ + E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ--EQEEKMQEQEEE 749
Query: 672 KYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTL 731
+ + +K+ W++ EK W + + E + + +I++
Sbjct: 750 MWEQEEKM----------------WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ- 792
Query: 732 KFFQTKLKKELQEKRKAARKRSLEEEKI--EEEPKDNATITMCRMRARHWKQISEIVGYD 789
+ K++ + ++ R K +EEK+ +EE M + W Q ++ G +
Sbjct: 793 ---EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQE 849
Score = 41.6 bits (96), Expect = 0.012
Identities = 55/260 (21%), Positives = 118/260 (45%), Gaps = 45/260 (17%)
Query: 519 KVPETTEEMMDLISYVEKARTVGIEELILRIQESK--RQMSYFLDVFLFPQEDLALNATV 576
++PE E++ + E+ + +E +R QE ++ + + QED
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ------ 545
Query: 577 LMWPRKINPIFDENDELIENAKHKK--ENELMAKREKLILEIEKESRRMEEFTEFAELER 634
MW E +E + + + K + E M K+ + E+E + ++ + E ER
Sbjct: 546 -MW---------EQEEKMRDQEQKMWDQEERMEKKTQ-----EQEKKTWDQEEKMREEER 590
Query: 635 MQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVL 694
M++ +R+ ++ ++E EE +Q +EE++ + E + + +K++ E +K +
Sbjct: 591 MREREKKMREEEEMMREQEEKMQ--EQEEKMQEQEEKMWEQEEKMQ---EQEEKMWEQEE 645
Query: 695 K-WQRSEKRWMDGGFLDLNGESMEAD-------VEEFSREIFKTLKFFQTKLKKELQEKR 746
K W++ EK W + + E + ++E +I++ Q K++K+ QE+
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE-----QEKMEKKTQEQE 700
Query: 747 KAA--RKRSLEEEKIEEEPK 764
K +++ EEE + E K
Sbjct: 701 KKTWDQEKMREEESMREREK 720
Score = 33.9 bits (76), Expect = 2.6
Identities = 39/186 (20%), Positives = 89/186 (47%), Gaps = 35/186 (18%)
Query: 596 NAKHKKEN----ELMAKREKLILEI----------EKESRRMEEFTEFAELERMQQYVTD 641
+ +HKK + EL +R+ L LE+ +K++ ++E AE E+ + + +
Sbjct: 189 STRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQL-N 247
Query: 642 VRQLQKRIQESE---EAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQR 698
V++L+++++ ++ VQ +EE+++ E + K++ E W++
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM---------WRQ 298
Query: 699 SEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEK 758
E+ + G+ E + + + +E K L+ + +L+++ +E R+ R EE+
Sbjct: 299 EER------LREQEGKMREQEEKMWRQE--KRLREQEKELREQEKELREQKELREQEEQM 350
Query: 759 IEEEPK 764
E+E K
Sbjct: 351 QEQEEK 356
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 48.9 bits (115), Expect = 8e-05
Identities = 69/311 (22%), Positives = 128/311 (41%), Gaps = 58/311 (18%)
Query: 506 ICSEFEAIKEHALKVPETTE-EMMDLISYVEKARTVGIEELILRIQESKRQMSYFL--DV 562
+ + +E KE + T E E + E+AR +E + + +E +RQ+ L +
Sbjct: 162 VVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERM--KAEEERRQLEDKLQAEA 219
Query: 563 FLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRR 622
L E+L L +E K KKE E + K+ + +E+E ++
Sbjct: 220 LLQQMEELKLKE-------------------VEATKLKKEQENLLKQRWELERLEEERKQ 260
Query: 623 MEEFTEFAELERM--QQYVTDVRQLQKRIQESEEAVQ-----FINKEEELFKWELTK--- 672
ME F + AEL R QY + + ++IQE EA + + KE+E + L +
Sbjct: 261 MEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQ 320
Query: 673 -YPELDKLKVNIEPYQKF-------FNFVLK------WQRSEKRW---------MDGGFL 709
++ +K IE + +L+ W++ E W + L
Sbjct: 321 VMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVL 380
Query: 710 DLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATI 769
+ ++ +E+ R ++LK + +L + L+E R+ AR+ E EK++ K
Sbjct: 381 TGRQQQIQEKIEQNRRAQEESLK-HREQLIRNLEEVRELARREKEESEKLKSARKQELEA 439
Query: 770 TMCRMRARHWK 780
+ R + W+
Sbjct: 440 QVAERRLQAWE 450
Score = 38.5 bits (88), Expect = 0.10
Identities = 38/172 (22%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 595 ENAKHKKENELMAKREKLILEIEKE----SRRMEEFTEFAELERMQQYVTDVRQLQKRIQ 650
E K +K L A+REKL +++E +R +EE L+ + +R+ +++
Sbjct: 70 EKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQERR-----IREQHGKLK 124
Query: 651 ESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLD 710
++E + + E+ L++ P+L ++++++ +QK + Q+ EK+ + +
Sbjct: 125 SAKEEQRKLIAEQLLYEHWKKNNPKLREMELDL--HQKHVVNSWEMQKEEKKQQE-ATAE 181
Query: 711 LNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKA-ARKRSLEEEKIEE 761
+ E + E RE + +K + +++L++K +A A + +EE K++E
Sbjct: 182 QENKRYENEYERARREALERMK--AEEERRQLEDKLQAEALLQQMEELKLKE 231
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 48.9 bits (115), Expect = 8e-05
Identities = 69/311 (22%), Positives = 128/311 (41%), Gaps = 58/311 (18%)
Query: 506 ICSEFEAIKEHALKVPETTE-EMMDLISYVEKARTVGIEELILRIQESKRQMSYFL--DV 562
+ + +E KE + T E E + E+AR +E + + +E +RQ+ L +
Sbjct: 162 VVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERM--KAEEERRQLEDKLQAEA 219
Query: 563 FLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRR 622
L E+L L +E K KKE E + K+ + +E+E ++
Sbjct: 220 LLQQMEELKLKE-------------------VEATKLKKEQENLLKQRWELERLEEERKQ 260
Query: 623 MEEFTEFAELERM--QQYVTDVRQLQKRIQESEEAVQ-----FINKEEELFKWELTK--- 672
ME F + AEL R QY + + ++IQE EA + + KE+E + L +
Sbjct: 261 MEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQ 320
Query: 673 -YPELDKLKVNIEPYQKF-------FNFVLK------WQRSEKRW---------MDGGFL 709
++ +K IE + +L+ W++ E W + L
Sbjct: 321 VMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVL 380
Query: 710 DLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATI 769
+ ++ +E+ R ++LK + +L + L+E R+ AR+ E EK++ K
Sbjct: 381 TGRQQQIQEKIEQNRRAQEESLK-HREQLIRNLEEVRELARREKEESEKLKSARKQELEA 439
Query: 770 TMCRMRARHWK 780
+ R + W+
Sbjct: 440 QVAERRLQAWE 450
Score = 38.5 bits (88), Expect = 0.10
Identities = 38/172 (22%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 595 ENAKHKKENELMAKREKLILEIEKE----SRRMEEFTEFAELERMQQYVTDVRQLQKRIQ 650
E K +K L A+REKL +++E +R +EE L+ + +R+ +++
Sbjct: 70 EKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQERR-----IREQHGKLK 124
Query: 651 ESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLD 710
++E + + E+ L++ P+L ++++++ +QK + Q+ EK+ + +
Sbjct: 125 SAKEEQRKLIAEQLLYEHWKKNNPKLREMELDL--HQKHVVNSWEMQKEEKKQQE-ATAE 181
Query: 711 LNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKA-ARKRSLEEEKIEE 761
+ E + E RE + +K + +++L++K +A A + +EE K++E
Sbjct: 182 QENKRYENEYERARREALERMK--AEEERRQLEDKLQAEALLQQMEELKLKE 231
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.5 bits (114), Expect = 1e-04
Identities = 94/463 (20%), Positives = 186/463 (40%), Gaps = 53/463 (11%)
Query: 498 KYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMS 557
K+ E E S K+ A + E + D +S T+ EEL +E ++
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEEL----KEKNAKLQ 227
Query: 558 YFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIE 617
L + + ++ LN L + + +L A H + EL + KL ++E
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK-ELQSVSAKLQAQVE 286
Query: 618 KES-----RRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTK 672
+ + +E + + E++Q++ +++ +++I+E EE ++ +EE++ + E
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR--EQEEKMRRQEEMM 344
Query: 673 YPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLK 732
+ + +K++ E + W++ EK E M + EE R + +
Sbjct: 345 WEKEEKMRRQEE---------MMWEKEEKMRRQ--------EEMMWEKEEKMRRQEEMMW 387
Query: 733 FFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTP 792
+ K++ EL+EK K +EEK +EE K A+ W+Q +I +
Sbjct: 388 EKEEKIR-ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE--- 443
Query: 793 DSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGV 852
K+ + + ++ ++ +E + M E I ++R
Sbjct: 444 ------EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK-- 495
Query: 853 CILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQW 912
+ E + + Q + + R I+ E +I+ E+++ R +E I E + W
Sbjct: 496 ---EKMHEQEEKIRKQ--EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE---QEEMW 547
Query: 913 LYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKV 955
E + E I + EE RQ Q D+ WR K ++ KV
Sbjct: 548 REEEKMHEQEKIWE---EEKRQEQE-DKMWRQEEKIREQEEKV 586
Score = 47.4 bits (111), Expect = 2e-04
Identities = 70/379 (18%), Positives = 164/379 (43%), Gaps = 47/379 (12%)
Query: 408 RKHYETYVEKYNWLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYT 467
+K + Y+E+ D ++E T++ ++ + EK + SE +
Sbjct: 188 KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE---------KS 238
Query: 468 MVRLDCEDLKTGLTNKAKAFANILLNDIASKYRKENECICSEFEA-IKEHAL--KVPETT 524
++L+ ++LK L L A KE + + ++ +A ++E+ L ++ +
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 525 EEMM-----DLISYVEKART----VGIEELILRIQESKRQMSYFLDVFLFPQEDLALNAT 575
EE M + + EK + + +E +R QE K + + ++ +E+
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ---EEMMWEKEEKMRRQE 355
Query: 576 VLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTE------- 628
+MW ++ E + K +++ E+M ++E+ I E+E++ E+ E
Sbjct: 356 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 415
Query: 629 ---FAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLK--VNI 683
E E+ Q+ + + +++I+E EE ++ +E+++++ E K E +K++
Sbjct: 416 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIR--EQEKKMWRQE-EKIHEQEKIREEEKR 472
Query: 684 EPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQ 743
+ ++ + K E+ W + E + E+ R+ + K++++ +
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ--------EEKIREQEE 524
Query: 744 EKRKAARKRSLEEEKIEEE 762
+ R+ K +EEKI E+
Sbjct: 525 KIREQEEKMWRQEEKIREQ 543
Score = 44.7 bits (104), Expect = 0.001
Identities = 58/267 (21%), Positives = 118/267 (44%), Gaps = 30/267 (11%)
Query: 492 LNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQ- 550
+++ K RK+ E + + E I+E K+ E E+M + + + EE + Q
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
Query: 551 ----ESKRQMSYFLDVFLFPQEDLALNATVLMW--PRKINPIFDENDELIE-----NAKH 599
E KRQ + ++ QE+ +W KI ++ E E K
Sbjct: 558 KIWEEEKRQEQ---EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 600 KKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFI 659
+++ E + ++E+ I E E++ R EE T+ E E+M + + + ++++QE EE +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQE-EKMGEQEEKMCEQEEKMQEQEETMW-- 671
Query: 660 NKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEAD 719
+EE++ + E + +K++ E Q ++ EK W + E M+
Sbjct: 672 RQEEKIREQEKKIREQEEKIREQEEMMQ---------EQEEKMWEQEEKMCEQEEKMQEQ 722
Query: 720 VEEFSREIFKTLKFFQTKLKKELQEKR 746
E+ R+ K ++ +++ QE++
Sbjct: 723 EEKMRRQ---EEKMWEQEVRLRQQEEK 746
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.1 bits (113), Expect = 1e-04
Identities = 62/275 (22%), Positives = 118/275 (42%), Gaps = 37/275 (13%)
Query: 492 LNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYV-EKARTVGIEELILRIQ 550
L + K RK+ E + + E ++E K+ E E+M + E+ + + +E LR Q
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 551 ESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKRE 610
+ R+ QE+ MW E +E K +++ E M ++E
Sbjct: 303 KKLRE-----------QEEQMQEQEEKMW---------EQEE-----KMREQEEKMWRQE 337
Query: 611 KLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESE---EAVQFINKEEELFK 667
+ + E EK+ R E+ E ERM + +R+ ++R++E E E + + +EE + +
Sbjct: 338 ERLWEQEKQMREQEQKMRDQE-ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 668 WELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREI 727
E E + ++ E QK + W++ EK W + + E + + E
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENM--WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE- 453
Query: 728 FKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEE 762
K ++ + K QE+ K+ +EK+ E+
Sbjct: 454 ----KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/176 (23%), Positives = 83/176 (47%), Gaps = 22/176 (12%)
Query: 589 ENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKR 648
E + E K + E + E+ + E EK+ R EE E E+MQ+ +R+ +++
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMREQEEK 596
Query: 649 IQESEEAVQFINKEEELFKWE--LTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDG 706
+ E EE +Q +EE++++ E + + E DK++ E + W++ EK
Sbjct: 597 MWEQEEKMQ--EQEEKMWEQEEKMWEQEEEDKMQEQEE---------MMWEQEEKM---- 641
Query: 707 GFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEE 762
E + EE RE + ++ + K++ + ++ R+ K +EEK+ E+
Sbjct: 642 ----QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Score = 43.5 bits (101), Expect = 0.003
Identities = 38/188 (20%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 595 ENAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEE 654
+ K +++ E M ++EK + E EKE R E+ E E +++++ +++ ++++ E EE
Sbjct: 267 QEGKMREQEEKMRRQEKRLREQEKELREQEK--ELREQKKLREQEEQMQEQEEKMWEQEE 324
Query: 655 AVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGE 714
++ +EE++++ E + + +++ E QK + + ++R + E
Sbjct: 325 KMR--EQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 715 SMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKI-EEEPKDNATITMCR 773
M E+ E + ++ + K+++E + R+ K +EE + E+E K+ +
Sbjct: 380 KMWEQEEKMQEE--ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 774 MRARHWKQ 781
+ + W+Q
Sbjct: 438 QKEKLWEQ 445
Score = 40.0 bits (92), Expect = 0.036
Identities = 34/171 (19%), Positives = 79/171 (46%), Gaps = 17/171 (9%)
Query: 589 ENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKR 648
E + + E K +E E M + ++ ++ ++E R +E + + E+MQ+ + + +++
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 649 IQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGF 708
+ E EE + +EE +++ E + +K+ W++ EK
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM----------------WEQEEKMREQEEK 661
Query: 709 LDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKI 759
+ E M+ EE RE + ++ + K++++ ++ R K +EEK+
Sbjct: 662 MREQEEKMQGQ-EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
Score = 38.9 bits (89), Expect = 0.080
Identities = 72/321 (22%), Positives = 126/321 (39%), Gaps = 54/321 (16%)
Query: 498 KYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMS 557
K +E + + + E ++E K+ E E+M + ++ + EE R+ E ++QM
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMRE-----QEEKMWRQEE---RLWEQEKQMR 348
Query: 558 YFLDVFLFPQEDLALNATVLMWP-----RKINPIFDENDELIENAKHKKENELMAKREKL 612
QE + MW R+ E +++ E + +E E + +REK
Sbjct: 349 --------EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 613 ILEIEKESRRMEE--------FTEFAELERMQQYVTDVRQL---QKRIQESEEAV----Q 657
+ E E+ R EE E E E QQ + + ++ Q+++QE EE + +
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 658 FINKEEELF-----KWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLN 712
I +EE++ W K E + E + + W + E+ W L
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM-WDQEERMWEQDERLREK 519
Query: 713 GESMEA-----DVEEFSREIFKT----LKFFQTKLKKELQEKRKAARKRSLEEEKI---E 760
E M EE RE KT K + + K +E+ + K+ EEE++ +
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 761 EEPKDNATITMCRMRARHWKQ 781
EE M + W+Q
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQ 600
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.1 bits (113), Expect = 1e-04
Identities = 59/271 (21%), Positives = 125/271 (46%), Gaps = 20/271 (7%)
Query: 500 RKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYF 559
R + +C E E + L+ E E++ VE+ + +EE+ L+ +E R++
Sbjct: 527 RMDPKCSFVEKERQRLENLRRKEEAEQLRR--QKVEEDKRRRLEEVKLKREERLRKVLQA 584
Query: 560 LDVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKE 619
+ +E+ ++I F + DE E AK ++ E AK++ ++E+
Sbjct: 585 RERVEQMKEEKK---------KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 635
Query: 620 SRRMEEFTEFAELERMQQYVTDVRQ---LQKRIQESEEAVQFINKEEELFKWELTKYPEL 676
R ++ E L +QQ + R LQK+ +E +E ++ + + L + + E
Sbjct: 636 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695
Query: 677 DKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQT 736
++ + ++ + +R ++R + E ++A+ E RE K L+ +
Sbjct: 696 ERREQERREQERRE----QERREQERQLAEQERRREQERLQAERELQERE--KALRLQKE 749
Query: 737 KLKKELQEKRKAARKRSLEEEKIEEEPKDNA 767
+L++EL+EK+K ++ L E +++EE + A
Sbjct: 750 QLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 47.8 bits (112), Expect = 2e-04
Identities = 124/609 (20%), Positives = 232/609 (38%), Gaps = 93/609 (15%)
Query: 267 VINLFTKKEALEGVKPEKLD---AFYSCVSTLMSNQLKDLLRRTVEGFVKLFDPKDQQRL 323
+ L +K+AL+ + LD A V+TL ++K L + V+ + + + R+
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK--LEQQVDDLEGSLEQEKKVRM 1046
Query: 324 PIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEA----------LQNVQTIPSWLSG 373
+ + + + D + DLE++ L ER+ + +++ Q + S L
Sbjct: 1047 DLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQK 1106
Query: 374 TSTPVNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETF 433
+ E E L A T +A V + + E E+ T+V+ IE
Sbjct: 1107 KLKELQARIEELEEELE-AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ-IEMN 1164
Query: 434 QTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMV-----RLDCEDLKTGLTNKAKAFA 488
+ + F + +E+ + H V ++D K K+
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1224
Query: 489 NILLNDIAS------KYRKENECICSEFE-AIKEHALKVPETTEEMMDLISYVEKARTVG 541
+ L+D+ S K + E +C E + EH K ET + DL S K +T
Sbjct: 1225 KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Query: 542 ---------IEELILRIQESKRQMSYFLDVFL--FPQEDLALNATVLMWPRKINPIFDEN 590
E LI ++ K + L+ +E A NA + +
Sbjct: 1285 GELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA----HALQSARHDC 1340
Query: 591 DELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQ 650
D L E ++++E E A+ ++++ + E + E ++R ++ ++L +R+Q
Sbjct: 1341 DLLRE--QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398
Query: 651 ESEEAVQFIN-KEEELFKWELTKYPELDKLKVNIE-----------PYQKFFNFVLKWQR 698
E+EEAV+ +N K L K + E++ L V++E + F + +W++
Sbjct: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
Query: 699 SEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEK 758
+ ES + + S E+F KLK +E + E +
Sbjct: 1459 KYEESQS------ELESSQKEARSLSTELF--------KLKNAYEESLEHLETFKRENKN 1504
Query: 759 IEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISA 818
++EE D ++E +G SG T+ ++ K+ E+ E+ SA
Sbjct: 1505 LQEEISD----------------LTEQLG-----SSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 819 GASKEFSLE 827
E SLE
Sbjct: 1544 LEEAEASLE 1552
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,250,101
Number of Sequences: 37866
Number of extensions: 5269273
Number of successful extensions: 16789
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 306
Number of HSP's that attempted gapping in prelim test: 14894
Number of HSP's gapped (non-prelim): 1623
length of query: 3092
length of database: 18,247,518
effective HSP length: 121
effective length of query: 2971
effective length of database: 13,665,732
effective search space: 40600889772
effective search space used: 40600889772
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.