Guide to the Human Genome
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Search of human proteins with 193211480

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193211480 superkiller viralicidic activity 2-like 2 [Homo
sapiens]
         (1042 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap...  2076   0.0  
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom...   573   e-163
gi|130484567 HFM1 protein [Homo sapiens]                              114   5e-25
gi|76880486 activating signal cointegrator 1 complex subunit 3 i...   111   4e-24
gi|139394648 DNA polymerase theta [Homo sapiens]                      107   8e-23
gi|40217847 activating signal cointegrator 1 complex subunit 3-l...    96   1e-19
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    92   3e-18
gi|110556640 DNA helicase HEL308 [Homo sapiens]                        87   1e-16
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom...    84   9e-16
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap...    80   8e-15
gi|14591902 RecQ protein-like [Homo sapiens]                           41   0.005
gi|14591904 RecQ protein-like [Homo sapiens]                           41   0.005
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...    39   0.020
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...    39   0.020
gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]                39   0.026
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       35   0.28 
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...    35   0.37 
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...    35   0.37 
gi|122937345 myosin VB [Homo sapiens]                                  35   0.48 
gi|116812616 RecQ protein-like 4 [Homo sapiens]                        34   0.63 
gi|110735439 Werner syndrome protein [Homo sapiens]                    34   0.82 
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent...    34   0.82 
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...    33   1.4  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        33   1.8  
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        33   1.8  
gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]        32   3.1  
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]                32   4.1  
gi|13376617 prostaglandin E synthase 2 [Homo sapiens]                  31   5.3  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    31   5.3  
gi|153945715 myosin VC [Homo sapiens]                                  31   5.3  

>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sapiens]
          Length = 1042

 Score = 2076 bits (5378), Expect = 0.0
 Identities = 1042/1042 (100%), Positives = 1042/1042 (100%)

Query: 1    MADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNG 60
            MADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNG
Sbjct: 1    MADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNG 60

Query: 61   KNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEE 120
            KNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEE
Sbjct: 61   KNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEE 120

Query: 121  DYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALR 180
            DYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALR
Sbjct: 121  DYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALR 180

Query: 181  EKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGS 240
            EKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGS
Sbjct: 181  EKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGS 240

Query: 241  EVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLH 300
            EVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLH
Sbjct: 241  EVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLH 300

Query: 301  KQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGD 360
            KQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGD
Sbjct: 301  KQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGD 360

Query: 361  QKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMV 420
            QKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMV
Sbjct: 361  QKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMV 420

Query: 421  EEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALF 480
            EEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALF
Sbjct: 421  EEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALF 480

Query: 481  ATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVD 540
            ATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVD
Sbjct: 481  ATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVD 540

Query: 541  EKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPG 600
            EKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPG
Sbjct: 541  EKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPG 600

Query: 601  VVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLV 660
            VVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLV
Sbjct: 601  VVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLV 660

Query: 661  KVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKP 720
            KVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKP
Sbjct: 661  KVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKP 720

Query: 721  DEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPI 780
            DEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPI
Sbjct: 721  DEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPI 780

Query: 781  DDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELK 840
            DDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELK
Sbjct: 781  DDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELK 840

Query: 841  KARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDL 900
            KARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDL
Sbjct: 841  KARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDL 900

Query: 901  SAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLS 960
            SAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLS
Sbjct: 901  SAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLS 960

Query: 961  SFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELE 1020
            SFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELE
Sbjct: 961  SFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELE 1020

Query: 1021 NKFAEGITKIKRDIVFAASLYL 1042
            NKFAEGITKIKRDIVFAASLYL
Sbjct: 1021 NKFAEGITKIKRDIVFAASLYL 1042


>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
            sapiens]
          Length = 1246

 Score =  573 bits (1478), Expect = e-163
 Identities = 361/1004 (35%), Positives = 542/1004 (53%), Gaps = 68/1004 (6%)

Query: 91   SLADLMPRVKVQSVETVEG----CTHEVALPAEE-----DYLPLKPRVGKAAKEYPFILD 141
            SL DL+ +    +V T E        + A+P +      D+  L P+    A ++ F  D
Sbjct: 256  SLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLIPQ---PAFQWAFEPD 312

Query: 142  AFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYRE 201
             FQ++AI  ++ + SV V+AHTSAGKTV AEYAIALA +   R I+TSPIKALSNQK+R+
Sbjct: 313  VFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRD 372

Query: 202  MYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSE 261
                F DVGL+TGDV ++P ASCL+MTTEILRSMLY GS+V+R++ WVIFDE+HY+ D E
Sbjct: 373  FRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVE 432

Query: 262  RGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIF 321
            RGVVWEE +I+LPD+V  + LSAT+PNA +FA+WI  L ++  +VI T  RP PL+HY+F
Sbjct: 433  RGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLF 492

Query: 322  PAGGD----GLHLVVDENGDFREDNFNTAMQVLRDA----GDLAKGDQKGRKGGTKGPSN 373
                      L L++D  G F    +  A++  ++            Q   +GG      
Sbjct: 493  TGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRG 552

Query: 374  VF-KIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLS 432
            V+  ++  +  R   PV++F+FS+  C+  A  +T LD  T  EK  +       +  L 
Sbjct: 553  VYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLR 612

Query: 433  DEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMP 492
              D++LPQV H+  LL RG+G+HH G+LPILKE +E+LFS GL+K LFATETFAMG+NMP
Sbjct: 613  GSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMP 672

Query: 493  ARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIG-KQL 551
            ARTV+F + RK DG  FR +  GEY+QM+GRAGRRG+D  G VIL+   ++       ++
Sbjct: 673  ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRM 732

Query: 552  LKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQ 611
            + G    L S F LTY M+LNLLRV+ +  E M+++SF +F   +      + +    ++
Sbjct: 733  MMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKR 792

Query: 612  YNKIVIPNEESVVI----YYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGD 667
               +  P+    ++    YY   ++L +    I+  I +    L  L  GR+V VKN+  
Sbjct: 793  LGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEH 852

Query: 668  DFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAK-------- 719
                GV++  S  S  +          V   L+ C K   ++        A+        
Sbjct: 853  HNALGVILQVSSNSTSR----------VFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLV 902

Query: 720  ------PDEKGEMQVVPVLVHLLSAISS--VRLYIPKDLRPVDNRQ-----------SVL 760
                  P+   +  VV +    ++AI++  +R+   K L     RQ           +V 
Sbjct: 903  GFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAAVT 962

Query: 761  KSIQE---VQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLET 817
             ++QE   + +  P G P LDP++D+ ++D  + +   +    E  +      + P    
Sbjct: 963  TAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPA 1022

Query: 818  VYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVA 877
             Y    ++ QI  +++   R L   +++L + E   R  VLR LG+   +  +++ GRVA
Sbjct: 1023 QYLKLRERMQIQKEMERL-RFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVA 1081

Query: 878  CEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQE 937
            C +SS  ELLLTE+MF+   + L  E+  ALLS  V Q       +L   L   + +++ 
Sbjct: 1082 CAMSS-HELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRA 1140

Query: 938  CAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCM 997
             AKRI +V     L    E ++      L++VVY WA G  F+ +  ++   EG ++RC+
Sbjct: 1141 VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI 1200

Query: 998  RRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLY 1041
            +RL E+ R +  AA+ +G   L  K     T ++RDIVFAASLY
Sbjct: 1201 QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244


>gi|130484567 HFM1 protein [Homo sapiens]
          Length = 1435

 Score =  114 bits (285), Expect = 5e-25
 Identities = 105/442 (23%), Positives = 188/442 (42%), Gaps = 85/442 (19%)

Query: 134 KEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ------RVIF 187
           KE+P+      +     +  +++ ++ A T +GKTV  E AI   L E        ++++
Sbjct: 276 KEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVY 335

Query: 188 TSPIKALSNQKYREMYEEFQDVGL----MTGDVTINPT-----ASCLVMTTEILRSML-- 236
            +PIKAL +Q++ +  E+F  +GL    +TGD  ++       A  ++ T E   SM   
Sbjct: 336 MAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRK 395

Query: 237 YRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPD---------------NVHYVF 281
           +R + +++ V   + DE+H ++D  RG   E  +  +                  + +V 
Sbjct: 396 WRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVA 455

Query: 282 LSATIPNARQFAEWICHLHKQP-CHVIYTDYRPTPLQHYI--FPAGGDGLHLVVDENGDF 338
           +SATIPNA   AEW+    +   C  +   +RP  LQ  +  FP   +      D   ++
Sbjct: 456 VSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNY 515

Query: 339 REDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKD 398
           +                                  +  +++M  ++  +P ++F  ++K 
Sbjct: 516 K----------------------------------IASVIQMYSDQ--KPTLVFCATRKG 539

Query: 399 CEAYALQMTK--LDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHH 456
            +  A  + K      T E+K+ +++         S  D KL  +      LK G   HH
Sbjct: 540 VQQAASVLVKDAKFIMTVEQKQRLQKY------AYSVRDSKLRDI------LKDGAAYHH 587

Query: 457 GGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGE 516
            G+    ++ +E  F+ G +  LF T T AMG+N+PA  V+  +   + G  F   S  +
Sbjct: 588 AGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGLFEEYSETD 647

Query: 517 YIQMSGRAGRRGMDDRGIVILM 538
            +QM GRAGR   D     ++M
Sbjct: 648 ILQMIGRAGRPQFDTTATAVIM 669


>gi|76880486 activating signal cointegrator 1 complex subunit 3
            isoform a [Homo sapiens]
          Length = 2202

 Score =  111 bits (277), Expect = 4e-24
 Identities = 118/417 (28%), Positives = 186/417 (44%), Gaps = 84/417 (20%)

Query: 156  SVLVSAHTSAGKTVCAEYAIALALRE--KQRVIFTSPIKALSNQKYREMYEEFQD----- 208
            +VL+ A T +GKTV AE AI     +    + ++ +P+KAL  ++  +     ++     
Sbjct: 1344 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK 1403

Query: 209  VGLMTGDVTIN----PTASCLVMTTE----ILRSMLYRGSEVMREVAWVIFDEIHYMRDS 260
            V  +TGDVT +      A  +V T E    + RS  ++    +++V  +I DEIH + + 
Sbjct: 1404 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRS--WQNRNYVQQVTILIIDEIHLLGE- 1460

Query: 261  ERGVVWEETIILLPDN---------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDY 311
            ERG V E  +I+   N         V  V LS  + NAR  A+W+ ++ +          
Sbjct: 1461 ERGPVLE--VIVSRTNFISSHTEKPVRIVGLSTALANARDLADWL-NIKQMGLFNFRPSV 1517

Query: 312  RPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNT-AMQVLRDAGDLAKGDQKGRKGGTKG 370
            RP PL+ +I   G  G H         R  + N  A Q +R                +  
Sbjct: 1518 RPVPLEVHI--QGFPGQHYCP------RMASMNKPAFQAIR----------------SHS 1553

Query: 371  PSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKK----MVEEVFSN 426
            P+              +PV+IF  S++     AL++      T+E+ K    M E    N
Sbjct: 1554 PA--------------KPVLIFVSSRRQTRLTALELIAF-LATEEDPKQWLNMDEREMEN 1598

Query: 427  AIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFA 486
             I  + D + KL         L  GIG+HH GL    ++T+E LF    ++ L AT T A
Sbjct: 1599 IIATVRDSNLKLT--------LAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLA 1650

Query: 487  MGINMPARTVLFTNARKFDGKDFRWIS--SGEYIQMSGRAGRRGMDDRGIVILMVDE 541
             G+N PA  V+      +DGK  R++     + +QM GRAGR   DD+G  +++V +
Sbjct: 1651 WGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHD 1707



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 105/457 (22%), Positives = 185/457 (40%), Gaps = 85/457 (18%)

Query: 152 DNNQSVLVSAHTSAGKTVCAEYAIALALRE----------KQRVIFTSPIKALSNQKYRE 201
           + N+++L+ A T AGKT  A   +   +R+          + ++++ +P+KAL+ +    
Sbjct: 490 NTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDY 549

Query: 202 MYEEFQDVGL----MTGDVTINPTASCLVMTTEILRSMLYRGSEVMRE----------VA 247
                + +G+    +TGD+ ++ +    ++ T++L +   +   V R+          V 
Sbjct: 550 FSRRLEPLGIIVKELTGDMQLSKSE---ILRTQMLVTTPEKWDVVTRKSVGDVALSQIVR 606

Query: 248 WVIFDEIHYMRDSERGVVWEETIILL-------PDNVHYVFLSATIPNARQFAEWICHLH 300
            +I DE+H + + +RG V E  +             +  + LSAT+PN    A +   LH
Sbjct: 607 LLILDEVHLLHE-DRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF---LH 662

Query: 301 KQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGD 360
             P               YI     DG    V     F        MQ L +  ++    
Sbjct: 663 VNP---------------YIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCY-- 705

Query: 361 QKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMV 420
                       NV K VK   +     V++F  ++      A+ + +   N        
Sbjct: 706 -----------ENVLKQVKAGHQ-----VMVFVHARNATVRTAMSLIERAKNCGHIPFFF 749

Query: 421 EEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALF 480
                + +  L+++  +  + + V  L   G  IHH G+L   +  +E LFS G IK L 
Sbjct: 750 PTQGHDYV--LAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLV 807

Query: 481 ATETFAMGINMPARTVLFTNARKFDGKDFRWISSG--EYIQMSGRAGRRGMDDRGI-VIL 537
            T T A G+N+PA  V+    + +  K   ++  G  + +Q+ GRAGR   D  G  +I+
Sbjct: 808 CTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIII 867

Query: 538 MVDEKMS---------PTIGKQLLKGSADPLNSAFHL 565
              +K+S           I  Q L+  AD LN+   L
Sbjct: 868 TTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIAL 904


>gi|139394648 DNA polymerase theta [Homo sapiens]
          Length = 2590

 Score =  107 bits (266), Expect = 8e-23
 Identities = 121/458 (26%), Positives = 204/458 (44%), Gaps = 100/458 (21%)

Query: 155 QSVLVSAHTSAGKTVCAEYAIALALRE-KQRVIFTSPIKALSNQKYREMYEEFQDVGLMT 213
           ++++ SA TSAGKT+ AE  I   + E +++ +F  P  +++ +K   +   FQ+VG+  
Sbjct: 109 KNLVYSAPTSAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIKV 168

Query: 214 ----GDVTINPTASCL---VMTTEILRSMLYRGSEV--MREVAWVIFDEIHYMRDSERGV 264
               G  + +   S L   V T E    ++ R  E   M  +  V+ DE+H + DS RG 
Sbjct: 169 DGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGY 228

Query: 265 VWE------------------ETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHV 306
           + E                  +    L + V  V +SAT+PN    A W+         +
Sbjct: 229 LLELLLTKICYITRKSASCQADLASSLSNAVQIVGMSATLPNLELVASWL------NAEL 282

Query: 307 IYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDL--AKGDQKGR 364
            +TD+RP PL                 E+       ++++M+++R+   +   KGD+   
Sbjct: 283 YHTDFRPVPLL----------------ESVKVGNSIYDSSMKLVREFEPMLQVKGDED-- 324

Query: 365 KGGTKGPSNVFKIVKMIMER--NFQPVIIFSFSKKDCEAYALQMTKLDFNTD-------- 414
                       +V +  E   +   V++F  SKK CE  A  + +  +N          
Sbjct: 325 -----------HVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEGLVK 373

Query: 415 ---------EEKKMVEEVFSNAIDCLSDEDKKLPQ-VEHVLP-LLKRGIGIHHGGLLPIL 463
                    E+K+++E         + D+ ++LP  ++ VL   +  G+  HH GL    
Sbjct: 374 PSECPPVILEQKELLE---------VMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEE 424

Query: 464 KETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGR 523
           ++ IE  F +GLI+ L AT T + G+N+PAR V+      F G+    ++   Y QM GR
Sbjct: 425 RDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVII-RTPIFGGRPLDILT---YKQMVGR 480

Query: 524 AGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNS 561
           AGR+G+D  G  IL + +    + G  LL+GS  P+ S
Sbjct: 481 AGRKGVDTVGESIL-ICKNSEKSKGIALLQGSLKPVRS 517


>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
            [Homo sapiens]
          Length = 2136

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 112/461 (24%), Positives = 193/461 (41%), Gaps = 78/461 (16%)

Query: 135  EYPFILDAFQREAIQCVDNNQ-SVLVSAHTSAGKTVCAEYAIALALREKQ--RVIFTSPI 191
            ++PF  +  Q +    V N+  +V V A T +GKT+CAE+AI   L +    R ++ +P+
Sbjct: 1324 KFPFF-NPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPM 1382

Query: 192  KALSNQKYREMYEEFQD-----VGLMTG----DVTINPTASCLVMTTE--ILRSMLYRGS 240
            +AL+ Q Y + YE+FQD     V L+TG    D+ +    + ++ T E   + S  ++  
Sbjct: 1383 EALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQR 1442

Query: 241  EVMREVAWVIFDEIHYMRDSERGVVWEETI-------ILLPDNVHYVFLSATIPNARQFA 293
            + ++ +   + DE+H +   E G V E            +   +  V LS+++ NA+  A
Sbjct: 1443 KNVQNINLFVVDEVHLI-GGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVA 1501

Query: 294  EWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA 353
             W+           + + RP PL+ +I      G ++             +T  ++L  A
Sbjct: 1502 HWL-GCSATSTFNFHPNVRPVPLELHI-----QGFNI------------SHTQTRLLSMA 1543

Query: 354  GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQM---TKLD 410
              +     K        P               +PVI+F  S+K     A+ +      D
Sbjct: 1544 KPVYHAITK------HSPK--------------KPVIVFVPSRKQTRLTAIDILTTCAAD 1583

Query: 411  FNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEIL 470
                      E+     ++ LSD   K          L  G+G  H GL P+ +  +E L
Sbjct: 1584 IQRQRFLHCTEKDLIPYLEKLSDSTLK--------ETLLNGVGYLHEGLSPMERRLVEQL 1635

Query: 471  FSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEY--IQMSGRAGRRG 528
            FS G I+ + A+ +   G+N+ A  V+  + + ++GK   ++    Y  +QM G A R  
Sbjct: 1636 FSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPL 1695

Query: 529  MDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNM 569
             DD G  ++M          K L     +PL    HL + M
Sbjct: 1696 QDDEGRCVIMCQGSKKDFFKKFLY----EPLPVESHLDHCM 1732



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 105/458 (22%), Positives = 191/458 (41%), Gaps = 81/458 (17%)

Query: 118 AEEDYLPLK--PRVGKAAKEYPFILDAFQREAIQC-VDNNQSVLVSAHTSAGKTVCAEYA 174
           +EE  LP++  P+  +A  E    L+  Q +  +  ++ ++++L+ A T AGKT     A
Sbjct: 457 SEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKT---NVA 513

Query: 175 IALALRE--------------KQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTIN- 219
           +   LRE                ++I+ +P+++L  +      +     G+   ++T + 
Sbjct: 514 LMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDH 573

Query: 220 -------PTASCLVMTTEILRSMLYRGSE--VMREVAWVIFDEIHYMRDSERGVVWE--- 267
                       +V T E    +  +G E    + V  +I DEIH + D +RG V E   
Sbjct: 574 QLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALV 632

Query: 268 ----ETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPA 323
                 I +  ++V  + LSAT+PN    A ++     +        +RP PL+      
Sbjct: 633 ARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ----- 687

Query: 324 GGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIME 383
                ++ + E    +        Q++ +                        + + IME
Sbjct: 688 ----TYVGITEKKAIKR------FQIMNEI-----------------------VYEKIME 714

Query: 384 R-NFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVE 442
                 V++F  S+K+    A  +  +    D     + E  S + + L  E ++   +E
Sbjct: 715 HAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG-SASTEVLRTEAEQCKNLE 773

Query: 443 HVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNAR 502
            +  LL  G  IHH G+  + +  +E LF++  I+ L +T T A G+N+PA TV+    +
Sbjct: 774 -LKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 832

Query: 503 KFDGKDFRWISSG--EYIQMSGRAGRRGMDDRGIVILM 538
            +  +  RW   G  + +QM GRAGR   D +G  IL+
Sbjct: 833 VYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILI 870


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
            partial [Homo sapiens]
          Length = 1700

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 110/461 (23%), Positives = 190/461 (41%), Gaps = 78/461 (16%)

Query: 135  EYPFILDAFQREAIQCVDNNQ-SVLVSAHTSAGKTVCAEYAIALALREKQ--RVIFTSPI 191
            ++PF  +  Q +    V N+  +V V A T +GKT+CAE+AI   L +    R ++ +P+
Sbjct: 888  KFPFF-NPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPM 946

Query: 192  KALSNQKYREMYEEFQD-----VGLMTG----DVTINPTASCLVMTTE--ILRSMLYRGS 240
            +    Q Y + YE+FQD     V L+TG    D+ +    + ++ T E   + S  ++  
Sbjct: 947  RLWQEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQR 1006

Query: 241  EVMREVAWVIFDEIHYMRDSERGVVWEETI-------ILLPDNVHYVFLSATIPNARQFA 293
            + ++ +   + DE+H +   E G V E            +   +  V LS+++ NA+  A
Sbjct: 1007 KNVQNINLFVVDEVHLI-GGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVA 1065

Query: 294  EWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA 353
             W+           + + RP PL+ +I      G ++             +T  ++L  A
Sbjct: 1066 HWL-GCSATSTFNFHPNVRPVPLELHI-----QGFNI------------SHTQTRLLSMA 1107

Query: 354  GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQM---TKLD 410
                                VF  +     +  +PVI+F  S+K     A+ +      D
Sbjct: 1108 ------------------KPVFHAITKHSPK--KPVIVFVPSRKQTRLTAIDILTTCAAD 1147

Query: 411  FNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEIL 470
                      E+     ++ LSD   K          L  G+G  H GL P+ +  +E L
Sbjct: 1148 IQRQRFLHCTEKDLIPYLEKLSDSTLK--------ETLLNGVGYLHEGLSPMERRLVEQL 1199

Query: 471  FSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEY--IQMSGRAGRRG 528
            FS G I+ + A+ +   G+N+ A  V+  +   ++GK   ++    Y  +QM G A R  
Sbjct: 1200 FSSGAIQVVVASRSLCWGMNVAAHLVIIMDTLYYNGKIHAYVDYPIYDVLQMVGHANRPL 1259

Query: 529  MDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNM 569
             DD G  ++M          K L     +PL    HL + M
Sbjct: 1260 QDDEGRCVIMCQGSKKDFFKKFLY----EPLPVESHLDHCM 1296



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 104/458 (22%), Positives = 190/458 (41%), Gaps = 81/458 (17%)

Query: 118 AEEDYLPLK--PRVGKAAKEYPFILDAFQREAIQC-VDNNQSVLVSAHTSAGKTVCAEYA 174
           +EE  LP++  P+  +A  E    L+  Q +  +  ++ ++++L+ A T AGKT     A
Sbjct: 21  SEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKT---NVA 77

Query: 175 IALALRE--------------KQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTIN- 219
           +   LRE                ++I+ +P+++L  +      +     G+   ++T + 
Sbjct: 78  LMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDH 137

Query: 220 -------PTASCLVMTTEILRSMLYRGSE--VMREVAWVIFDEIHYMRDSERGVVWE--- 267
                       +V T E    +  +G E    + V  ++ DEIH + D +RG V E   
Sbjct: 138 QLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHD-DRGPVLEALV 196

Query: 268 ----ETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPA 323
                 I +  ++V  + LSAT+PN    A ++     +        +RP PL+      
Sbjct: 197 ARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ----- 251

Query: 324 GGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIME 383
                ++ + E    +        Q++ +                        + + IME
Sbjct: 252 ----TYVGITEKKAIKR------FQIMNEI-----------------------VYEKIME 278

Query: 384 R-NFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVE 442
                 V++F  S+K+    A  +  +    D     + E  S + + L  E ++   +E
Sbjct: 279 HAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG-SASTEVLRTEAEQCKNLE 337

Query: 443 HVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNAR 502
            +  LL  G  IHH G+  + +  +E LF +  I+ L +T T A G+N+PA TV+    +
Sbjct: 338 -LKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 396

Query: 503 KFDGKDFRWISSG--EYIQMSGRAGRRGMDDRGIVILM 538
            +  +  RW   G  + +QM GRAGR   D +G  IL+
Sbjct: 397 VYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILI 434


>gi|110556640 DNA helicase HEL308 [Homo sapiens]
          Length = 1101

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 127/575 (22%), Positives = 241/575 (41%), Gaps = 107/575 (18%)

Query: 24  KKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIE 83
           ++ ++ D+   K    S     K     L++  T N K            PIF +  +++
Sbjct: 241 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAK---------AQTPIFSRSKQLK 291

Query: 84  ESI-TEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDA 142
           +++ +E++++A           +TVE  ++++       +  L  +V     ++  I   
Sbjct: 292 DTLLSEEINVAK----------KTVESSSNDLG-----PFYSLPSKVRDLYAQFKGIEKL 336

Query: 143 FQRE----AIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE----KQRVIFTSPIKAL 194
           ++ +     +  V   ++++ S  TS GKT+ AE    L L+E    ++ V+   P  A+
Sbjct: 337 YEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEI---LMLQELLCCRKDVLMILPYVAI 393

Query: 195 SNQKYREMYEEFQDVGLMTGDVT-----INPTA-----SCLVMTTEILRSMLYRGSEVMR 244
             +K   +     ++G    +         PT      S  + T E   S++    E  R
Sbjct: 394 VQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGR 453

Query: 245 --EVAWVIFDEIHYMRDSERGVVWEET---IILLPDNVHYVFLSATIPNARQFAEWICHL 299
              +  V+ DE+H + +  RG   E T   I+        + +SAT+ N     +++   
Sbjct: 454 IDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFL--- 510

Query: 300 HKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVL--RDAGDLA 357
                    + +RP  L+ Y+     D ++ V     D + +N  T  ++L  + +  L 
Sbjct: 511 ---QAEYYTSQFRPVELKEYL--KINDTIYEV-----DSKAENGMTFSRLLNYKYSDTLK 560

Query: 358 KGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKL---DFNTD 414
           K D          P ++  +V  ++       ++F  SKK+CE  A  + K    ++   
Sbjct: 561 KMD----------PDHLVALVTEVIPN--YSCLVFCPSKKNCENVAEMICKFLSKEYLKH 608

Query: 415 EEKKMVEEVFSNAIDCLSDEDKKLPQVEH--VLPLLKR----GIGIHHGGLLPILKETIE 468
           +EK+  E +            K L  + +  + P+LKR    G+  HH GL    ++ +E
Sbjct: 609 KEKEKCEVI------------KNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLE 656

Query: 469 ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRG 528
             +S G++     T T A G+N+PAR V+      +  K+F  +   +Y QM GRAGR G
Sbjct: 657 EAYSTGVLCLFTCTSTLAAGVNLPARRVIL--RAPYVAKEF--LKRNQYKQMIGRAGRAG 712

Query: 529 MDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAF 563
           +D  G  IL++ EK      +Q+L+    PL + +
Sbjct: 713 IDTIGESILILQEKDK----QQVLELITKPLENCY 743


>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
            sapiens]
          Length = 1706

 Score = 83.6 bits (205), Expect = 9e-16
 Identities = 54/128 (42%), Positives = 74/128 (57%), Gaps = 10/128 (7%)

Query: 447  LLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDG 506
            L +RGIG HH  +    KE +EILF +GLI+ + ATET A+GI+MP ++V+F        
Sbjct: 1240 LAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVF-------A 1292

Query: 507  KDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLT 566
            +D  ++ +  Y QMSGRAGRRG D  G V     +   P I K+LL  S   L   F L+
Sbjct: 1293 QDSVYLDALNYRQMSGRAGRRGQDLLGNVYFF--DIPLPKI-KRLLASSVPELRGQFPLS 1349

Query: 567  YNMVLNLL 574
              +VL L+
Sbjct: 1350 ITLVLRLM 1357



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 57/190 (30%), Positives = 89/190 (46%), Gaps = 19/190 (10%)

Query: 122 YLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE 181
           YL    R  +  +   FI +A+Q+E +  VD N+S ++ A TS+GKT  + Y +   LRE
Sbjct: 726 YLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRE 785

Query: 182 KQ--RVIFTSPIKALSNQKYREMYEEFQDV--------GLMTGDVTINPTASCLVMTT-- 229
                V++ +P K+L  Q    +   F           G  T D   N   +C V+ T  
Sbjct: 786 SDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHN-VLNCQVLITVP 844

Query: 230 ---EILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATI 286
              EIL    +R   V R + +VIFDE+HY+        WE  ++++     ++ LSATI
Sbjct: 845 ECFEILLLAPHRQKWVER-IRYVIFDEVHYLGREVGAKFWELLLVII--RCPFLVLSATI 901

Query: 287 PNARQFAEWI 296
            N     +W+
Sbjct: 902 NNPNLLTKWL 911


>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
          Length = 1712

 Score = 80.5 bits (197), Expect = 8e-15
 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 10/133 (7%)

Query: 442  EHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNA 501
            E +  L +RGIG HH  +    K+ +EILF +G ++ + AT T A+G+NMP ++V+F   
Sbjct: 1251 EELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVF--- 1307

Query: 502  RKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNS 561
                 ++  ++ +  Y QMSGRAGRRG D  G V     +   P IGK L+K +   L  
Sbjct: 1308 ----AQNSVYLDALNYRQMSGRAGRRGQDLMGDVYFF--DIPFPKIGK-LIKSNVPELRG 1360

Query: 562  AFHLTYNMVLNLL 574
             F L+  +VL L+
Sbjct: 1361 HFPLSITLVLRLM 1373



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 54/174 (31%), Positives = 88/174 (50%), Gaps = 19/174 (10%)

Query: 138 FILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQR--VIFTSPIKALS 195
           FI D +QRE +  VD N+S ++ A TS+GKT  + Y +   L+E     V++ +P KAL 
Sbjct: 762 FIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALV 821

Query: 196 NQKYREMYEEFQDVGLMTGDVTI--------NPTASCLVMTT-----EILRSMLYRGSEV 242
           NQ    +   F    L +G+V          +   +C V+ T     EIL    +R + V
Sbjct: 822 NQVAATVQNRFTK-NLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWV 880

Query: 243 MREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWI 296
            +++ +VIFDE+H +       +WE  ++++     ++ LSATI N     EW+
Sbjct: 881 -KKIRYVIFDEVHCLGGEIGAEIWEHLLVMI--RCPFLALSATISNPEHLTEWL 931


>gi|14591902 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 12/106 (11%)

Query: 425 SNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATET 484
           S  I C S +D +  QV   L  L    G +H  L P  K T+   +S   I+ + AT  
Sbjct: 316 SGIIYCFSQKDSE--QVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVA 373

Query: 485 FAMGINMP-ARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGM 529
           F MGI+ P  R V+  +  K         S   Y Q SGRAGR  M
Sbjct: 374 FGMGIDKPDVRFVIHHSMSK---------SMENYYQESGRAGRDDM 410


>gi|14591904 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 12/106 (11%)

Query: 425 SNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATET 484
           S  I C S +D +  QV   L  L    G +H  L P  K T+   +S   I+ + AT  
Sbjct: 316 SGIIYCFSQKDSE--QVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVA 373

Query: 485 FAMGINMP-ARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGM 529
           F MGI+ P  R V+  +  K         S   Y Q SGRAGR  M
Sbjct: 374 FGMGIDKPDVRFVIHHSMSK---------SMENYYQESGRAGRDDM 410


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score = 39.3 bits (90), Expect = 0.020
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 16/160 (10%)

Query: 144 QREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-----RVIFTSPIKALSNQK 198
           QR+ I  + + + V+  A T +GKT C    +   L+        R +  SP + L+ Q 
Sbjct: 123 QRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGARALILSPTRELALQT 182

Query: 199 YREMYEEFQDVGLMT-----GD------VTINPTASCLVMTTEILRSMLYRGSEVMREVA 247
            +   E  +  GL T     GD        ++     ++ T   L  +    S  ++ V 
Sbjct: 183 LKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVE 242

Query: 248 WVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIP 287
           +V+FDE   + +       +E I  LP     V  SAT+P
Sbjct: 243 YVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLP 282


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score = 39.3 bits (90), Expect = 0.020
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 16/160 (10%)

Query: 144 QREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-----RVIFTSPIKALSNQK 198
           QR+ I  + + + V+  A T +GKT C    +   L+        R +  SP + L+ Q 
Sbjct: 123 QRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGARALILSPTRELALQT 182

Query: 199 YREMYEEFQDVGLMT-----GD------VTINPTASCLVMTTEILRSMLYRGSEVMREVA 247
            +   E  +  GL T     GD        ++     ++ T   L  +    S  ++ V 
Sbjct: 183 LKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVE 242

Query: 248 WVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIP 287
           +V+FDE   + +       +E I  LP     V  SAT+P
Sbjct: 243 YVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLP 282


>gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]
          Length = 786

 Score = 38.9 bits (89), Expect = 0.026
 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 8/92 (8%)

Query: 477 KALFATETFAMGINMPARTVLF-----TNARKFDGKDFRWISSGEYIQMSGRAGR-RGMD 530
           K L AT+   MG+N+  R ++F      +  +   ++   I++ + +Q++GRAGR     
Sbjct: 419 KILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRF 478

Query: 531 DRGIVILMVDEKMSPTIGKQLLKGSADPLNSA 562
             G V  M  E +S  + K++LK   DP+ +A
Sbjct: 479 KEGEVTTMNHEDLS--LLKEILKRPVDPIRAA 508



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 18/125 (14%)

Query: 160 SAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGD--VT 217
           S  T++GKT    +AI      K  V +  P+K L+++ + +         L+TG+  VT
Sbjct: 206 SGPTNSGKTY---HAIQKYFSAKSGV-YCGPLKLLAHEIFEKSNAAGVPCDLVTGEERVT 261

Query: 218 INPT---ASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETII-LL 273
           + P    AS +  T E+          V       + DEI  +RD  RG  W   ++ L 
Sbjct: 262 VQPNGKQASHVSCTVEMC--------SVTTPYEVAVIDEIQMIRDPARGWAWTRALLGLC 313

Query: 274 PDNVH 278
            + VH
Sbjct: 314 AEEVH 318


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 35.4 bits (80), Expect = 0.28
 Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 16/164 (9%)

Query: 371 PSNVFKIVKMIMERNFQPV-IIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVF----- 424
           P  V+K+ K  M+  ++ V ++   ++K   A  ++   +  +  +   ++ +V      
Sbjct: 330 PQWVYKVAKKYMKSRYEQVDLVGKMTQK--AATTVEHLAIQCHWSQRPAVIGDVLQVYSG 387

Query: 425 SNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATET 484
           S     +  E KK      + P +K+     HG +    +E     F EG  K L AT  
Sbjct: 388 SEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNV 447

Query: 485 FAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRG 528
            A G+++P   ++  ++   D +         YI  SGR GR G
Sbjct: 448 AARGLDIPEVDLVIQSSPPQDVES--------YIHRSGRTGRAG 483


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
           [Homo sapiens]
          Length = 994

 Score = 35.0 bits (79), Expect = 0.37
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 33/175 (18%)

Query: 144 QREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-----RVIFTSP--IKALSN 196
           Q+E +  +DN+Q  ++S  T  GKT      I     E+      R++ T P  I A+S 
Sbjct: 213 QKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISV 272

Query: 197 QKYREMYEEFQDVGLMTGDVT----------INPTASCLVMTTEILRSMLYRGSEVMREV 246
            + R   E  +  G  +G+ T               S L  TT I+   L +    +  V
Sbjct: 273 AE-RVAAERAESCG--SGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWL-QSDPYLSSV 328

Query: 247 AWVIFDEIHYMRDSERGVVWEETIILLPDNVHY------VFLSATIPNARQFAEW 295
           + ++ DEIH     ER +  +  + ++ D +++      + +SAT+ NA +F+E+
Sbjct: 329 SHIVLDEIH-----ERNLQSDVLMTVVKDLLNFRSDLKVILMSATL-NAEKFSEY 377


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
           [Homo sapiens]
          Length = 1008

 Score = 35.0 bits (79), Expect = 0.37
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 33/175 (18%)

Query: 144 QREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-----RVIFTSP--IKALSN 196
           Q+E +  +DN+Q  ++S  T  GKT      I     E+      R++ T P  I A+S 
Sbjct: 213 QKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISV 272

Query: 197 QKYREMYEEFQDVGLMTGDVT----------INPTASCLVMTTEILRSMLYRGSEVMREV 246
            + R   E  +  G  +G+ T               S L  TT I+   L +    +  V
Sbjct: 273 AE-RVAAERAESCG--SGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWL-QSDPYLSSV 328

Query: 247 AWVIFDEIHYMRDSERGVVWEETIILLPDNVHY------VFLSATIPNARQFAEW 295
           + ++ DEIH     ER +  +  + ++ D +++      + +SAT+ NA +F+E+
Sbjct: 329 SHIVLDEIH-----ERNLQSDVLMTVVKDLLNFRSDLKVILMSATL-NAEKFSEY 377


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 10/57 (17%)

Query: 152 DNNQSVLVSAHTSAGKTVCAEYAI---------ALALREKQRVIFTSPI-KALSNQK 198
           + NQS++VS  + AGKTV A+YA+         A     +++V+ +SPI +A+ N K
Sbjct: 154 EKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETNIEEKVLASSPIMEAIGNAK 210


>gi|116812616 RecQ protein-like 4 [Homo sapiens]
          Length = 1208

 Score = 34.3 bits (77), Expect = 0.63
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 455 HHGGLLPILKETIEILFSEGLIKALFATETFAMGINMP-ARTVLFTNARKFDGKDFRWIS 513
           +H G+    +  ++  F +G ++ + AT  F MG++ P  R VL               S
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPP---------S 794

Query: 514 SGEYIQMSGRAGRRG 528
              Y+Q  GRAGR G
Sbjct: 795 FESYVQAVGRAGRDG 809


>gi|110735439 Werner syndrome protein [Homo sapiens]
          Length = 1432

 Score = 33.9 bits (76), Expect = 0.82
 Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 10/95 (10%)

Query: 436 KKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGIN-MPAR 494
           K   QV   L  L    G +H G+    ++ I   F    I+ + AT  F MGIN    R
Sbjct: 775 KMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIR 834

Query: 495 TVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGM 529
            V+   A K             Y Q  GRAGR G+
Sbjct: 835 QVIHYGAPK---------DMESYYQEIGRAGRDGL 860


>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
           helicase, partial [Homo sapiens]
          Length = 1140

 Score = 33.9 bits (76), Expect = 0.82
 Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 10/95 (10%)

Query: 436 KKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGIN-MPAR 494
           K   QV   L  L    G +H G+    ++ I   F    I+ + AT  F MGIN    R
Sbjct: 483 KMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIR 542

Query: 495 TVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGM 529
            V+   A K             Y Q  GRAGR G+
Sbjct: 543 QVIHYGAPK---------DMESYYQEIGRAGRDGL 568


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score = 33.1 bits (74), Expect = 1.4
 Identities = 50/266 (18%), Positives = 112/266 (42%), Gaps = 24/266 (9%)

Query: 388 PVIIFSFSKKDCEAYALQ-MTKLDFNTDEEKK-----MVEEVFSNAIDCLSDEDKKLPQV 441
           PV IF  S  D   +  Q   ++  N + +++     ++   F++ +   +   K+  ++
Sbjct: 420 PVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM 479

Query: 442 EHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPA-RTVL-FT 499
             +L L+   +G  HG L    +      F +  I  L AT+  A G+++   +TV+ FT
Sbjct: 480 HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFT 539

Query: 500 NARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPL 559
                            Y+   GR  R G   R + ++  DE+    + K+++K +  P+
Sbjct: 540 MPNTIK----------HYVHRVGRTARAGRAGRSVSLVGEDER---KMLKEIVKAAKAPV 586

Query: 560 NSAFHLTYNMVLNLL-RVEEINPE-YMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVI 617
            +   L  +++L    ++E++  + Y + +   + +  +     +   K   E+  + V+
Sbjct: 587 KARI-LPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVV 645

Query: 618 PNEESVVIYYKIRQQLAKLGKEIEEY 643
              E      K  ++  K+ K ++E+
Sbjct: 646 QEPERSWFQTKEERKKEKIAKALQEF 671


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 10/57 (17%)

Query: 152 DNNQSVLVSAHTSAGKTVCAEYAI---------ALALREKQRVIFTSPI-KALSNQK 198
           + NQS++VS  + AGKTV A+YA+         A     +++V+ ++PI +++ N K
Sbjct: 154 ERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAK 210


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 10/57 (17%)

Query: 152 DNNQSVLVSAHTSAGKTVCAEYAI---------ALALREKQRVIFTSPI-KALSNQK 198
           + NQS++VS  + AGKTV A+YA+         A     +++V+ ++PI +++ N K
Sbjct: 154 ERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAK 210


>gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
          Length = 1132

 Score = 32.0 bits (71), Expect = 3.1
 Identities = 24/103 (23%), Positives = 42/103 (40%), Gaps = 31/103 (30%)

Query: 365  KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQM------------------ 406
            K  T   S +F +VK    ++  P ++ S ++ DC+ Y  +M                  
Sbjct: 1020 KNPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKK 1079

Query: 407  ------------TKLDFNTD-EEKKMVEEVFSNAIDCLSDEDK 436
                         K  FNTD  E   + ++F+NA++ L +E+K
Sbjct: 1080 LVETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDEEEK 1122


>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
          Length = 515

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 19/125 (15%)

Query: 10  FSVFEGDSTTAAGTKKDKEK---DKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDV 66
           +SVFEGD+      ++ KEK    K  W G       + K +D  +   S+NN  N R +
Sbjct: 111 YSVFEGDTLVLRCHRRRKEKLTAVKYTWNG--NILSISNKSWDLLIPQASSNNNGNYRCI 168

Query: 67  DFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVET--VEG----CTHEVALPAEE 120
            + G +  +F    +I       + + +L P  ++++ ++   EG     + E  LP E 
Sbjct: 169 GY-GDENDVFRSNFKI-------IKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPER 220

Query: 121 DYLPL 125
              PL
Sbjct: 221 SDTPL 225


>gi|13376617 prostaglandin E synthase 2 [Homo sapiens]
          Length = 377

 Score = 31.2 bits (69), Expect = 5.3
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 17/85 (20%)

Query: 575 RVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYN--KIVI-----------PNEE 621
           +V E+NP   + ++  +F  YR +P +V +   S +Q N   ++I           P EE
Sbjct: 128 QVVEVNP---VRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEE 184

Query: 622 SVVIYYKIRQQLAKLGKEIEEYIHK 646
            ++ YY   + + + GKE+ E+ +K
Sbjct: 185 -IITYYPAMKAVNEQGKEVTEFGNK 208


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 31.2 bits (69), Expect = 5.3
 Identities = 20/81 (24%), Positives = 35/81 (43%)

Query: 15  GDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEP 74
           GDS+       ++E++        GS    GK+   KL  +     K+KR  + E  D+ 
Sbjct: 83  GDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDD 142

Query: 75  IFGKKPRIEESITEDLSLADL 95
              K+P+    + ED  + D+
Sbjct: 143 DDSKEPKSSAQLLEDWGMEDI 163


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 31.2 bits (69), Expect = 5.3
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 152 DNNQSVLVSAHTSAGKTVCAEYAI 175
           + NQS++VS  + AGKTV A YA+
Sbjct: 152 NRNQSIIVSGESGAGKTVSARYAM 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,692,093
Number of Sequences: 37866
Number of extensions: 1698923
Number of successful extensions: 4594
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 4512
Number of HSP's gapped (non-prelim): 70
length of query: 1042
length of database: 18,247,518
effective HSP length: 112
effective length of query: 930
effective length of database: 14,006,526
effective search space: 13026069180
effective search space used: 13026069180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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